General

General Evidence Ranking

Within this category, verdicts with higher evidence scores appear first. Verdicts without a score stay lower in the same list.

• B 74 Cranberry (proanthocyanidins, PAC) x Urinary tract and bladder health: inhibition of harmful bacterial adhesion in the urinary tract and reduced risk of recurrent urinary tract infection
  There is clinical RCT and meta-analysis evidence for prevention of recurrent UTI, but broadening this to treatment of current cystitis or improveme... · View verdict →
• C 58 Folate/folic acid (vitamin B9) x Compound claims for anemia, pregnancy, and cardiovascular health
  Periconceptional neural-tube-defect prevention is A-grade, but advertising that bundles general anemia and cardiovascular prevention extends beyond... · View verdict →
• C 52 Iodine x Thyroid function
  Evidence for correcting deficiency is established, but general thyroid-function-improvement supplementation claims in iodine-sufficient regions are... · View verdict →
• C 48 Chlorella (chlorella) x Detoxification, immunity, and cholesterol
  There are signals for cholesterol and immune markers, but the detoxification claim has very weak human efficacy evidence. · View verdict →
• C 46 Low-molecular-weight collagen (hydrolyzed collagen peptides) x claims of superior absorption rate and molecular weight
  The evidence is conflicting or limited · View verdict →
• C 45 Noni (noni, Morinda citrifolia) x Anti-inflammatory and cure-all-style claims
  The core leap is extending ingredient/animal mechanisms and smoker surrogate markers into perceived or disease effects described as 'removing infla... · View verdict →
• C 44 Krill oil (phospholipid omega-3) x superior absorption and blood markers versus omega-3
  Repeatedly positive lipid-marker meta-analyses make grade C more appropriate than D, but small studies, product variation, conflicting findings, an... · View verdict →
• C 44 Chlorophyllin (distinct from liquid chlorophyll) x Body-odor reduction and detoxification
  Human trials evaluated chlorophyllin rather than liquid chlorophyll; general odor is D, the aflatoxin surrogate is C, and general detoxification is... · View verdict →
• C 43 Multivitamin/multimineral x General health, fatigue, and disease prevention
  Deficiency correction is a separate issue; consistent clinical evidence does not support healthy adults' general health, fatigue, and disease-preve... · View verdict →
• C 42 Balloon flower root (Platycodon grandiflorus, platycodin/platycodin D-series saponins) x bronchial health, cough, and phlegm
  There is no RCT showing that balloon flower root/platycodin alone reduces cough or phlegm in humans; evidence remains preclinical, surrogate-marker... · View verdict →
• C 42 Modified citrus pectin x Heavy-metal elimination and detoxification
  Only uncontrolled excretion-surrogate signals exist for the specific low-molecular-weight PectaSol product, so they cannot be generalized to generi... · View verdict →
• C 42 Clinoptilolite zeolite x Heavy-metal adsorption and systemic detoxification
  One sponsored RCT supports reduced intestinal uptake of simultaneously ingested lead, but removal of stored metals and systemic detoxification are... · View verdict →
• C 42 Bentonite clay x Gut cleansing and systemic toxin removal
  Reduction of aflatoxin absorption has been repeated with a specific refined material, but gut cleansing and general systemic detoxification remain... · View verdict →
• D 27 Cilantro leaf extract x Heavy-metal elimination and detoxification
  Widely cited evidence comes from animals and laboratory systems, while the identified 32-person controlled human trial was negative for lead elimin... · View verdict →
• D 22 D-mannose x Prevention of recurrent urinary tract infection
  The independent 598-person placebo-controlled trial and subsequent null RCT meta-analysis receive more weight than the early unblinded positive res... · View verdict →
• F 12 Colloidal silver x Infection prevention and enhanced immunity
  Regulators did not recognize disease-treatment or prevention efficacy, and intranasal chronic-rhinosinusitis trials found no significant improvemen... · View verdict →
• ? score not listed Activated charcoal capsules x Systemic toxin removal and detoxification
  Gastrointestinal adsorption soon after an acute ingestion and routine systemic detoxification are different claims, and the latter has no human eff... · View verdict →
• ? score not listed Irish sea moss (Chondrus crispus) x Thyroid, immune, and general health
  Iodine-content and animal data exist, but no direct human trial tested the target benefits, resulting in a question-mark grade. · View verdict →
• ? score not listed Monolaurin (glycerol monolaurate) x Antibacterial, antiviral, and immune support
  Strong in vitro signals and a null topical RCT exist, but oral infection and immune efficacy literature does not, resulting in a question-mark grade. · View verdict →