CHAMGAP
CATEGORY HUB

Eye

Eye verdicts ranked by evidence score. 121 verdicts in this category.

43 foods and supplements claimed to help eye health, ranked by evidence
Drugs and procedures removed — only what you swallow, ordered by how strong the evidence is.

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Eye Evidence Ranking

Within this category, verdicts with higher evidence scores appear first. Verdicts without a score stay lower in the same list.

A 90 Panretinal photocoagulation (PRP, standard retinal laser, prescribed procedure) Prevention of severe visual loss and blindness in high-risk proliferative diabetic retinopathy
A 90 Focal or grid retinal laser photocoagulation (prescription ophthalmic procedure) Prevention of moderate vision loss in clinically significant diabetic macular edema
A 88 Ranibizumab (anti-VEGF monoclonal antibody, intravitreal injection, prescription medicine) Improved vision and reduced vision loss in center-involved diabetic macular edema
A 86 An additional 40 minutes outdoors on school days Reduced first onset of myopia in children without baseline myopia
A 82 Cefuroxime sodium 1 mg/0.1 mL intracamerally (second-generation cephalosporin; approval status varies by country) Prevention of postoperative endophthalmitis when injected into the anterior chamber at the end of cataract surgery
B 79 Latanoprost (Xalatan, prescription eye drops) Slowing progression of visual-field loss in open-angle glaucoma
B 79 Aflibercept (prescription intravitreal anti-VEGF injection; Eylea) Prevention of vision loss and improvement of vision in neovascular age-related macular degeneration
B 78 Bimatoprost (a prescription prostamide ocular hypotensive; Lumigan) Lowering of intraocular pressure in open-angle glaucoma and ocular hypertension
B 78 Acyclovir or aciclovir (prescription oral guanosine-analogue antiviral) Prevention of recurrent ocular HSV and stromal keratitis in adults with recent ocular herpes simplex disease
B 78 Fenofibrate (PPAR-alpha agonist, prescription drug; retinopathy use is off-label in many jurisdictions) Reduced progression of diabetic retinopathy and need for first laser treatment in type 2 diabetes
B 77 Selective laser trabeculoplasty (SLT, 532-nm frequency-doubled Q-switched Nd:YAG ophthalmic procedure) Reduced disease progression and need for incisional glaucoma surgery as first-line treatment for open-angle glaucoma or ocular hypertension
B 75 Timolol maleate (prescription nonselective beta-blocker ophthalmic drug) Lowered intraocular pressure in open-angle glaucoma and ocular hypertension
B 74 Faricimab (dual VEGF/Ang-2 antibody, Vabysmo, prescription medicine) Maintenance of visual improvement with dosing intervals up to 16 weeks in wet age-related macular degeneration
B 74 Bevacizumab (prescription anti-VEGF monoclonal antibody; off-label ophthalmic use) Improved vision and macular thickness with intravitreal injection in center-involved diabetic macular edema
B 74 Verteporfin (benzoporphyrin photosensitizer for photodynamic therapy, Visudyne, prescription infusion plus laser procedure) Prevention of moderate or severe vision loss in wet age-related macular degeneration with classic choroidal neovascularization
B 74 Adhesive occlusion patch for amblyopia (non-drug ophthalmic product) Visual-acuity improvement and treatment success in residual childhood amblyopia after refractive correction
B 74 Early pars plana vitrectomy (vitreoretinal microsurgery, prescription procedure) Prevention of long-term severe visual loss and recovery of useful vision in severe vitreous hemorrhage and proliferative diabetic retinopathy in type 1 diabetes
B 74 Immediate pars plana vitrectomy (prescribed vitreoretinal surgery) Prevention of severe visual loss in eyes with light-perception-only vision from bacterial endophthalmitis after cataract surgery
B 72 Docosahexaenoic acid (DHA), retinal and visual-development axis Maintenance of retinal function and infant visual development
B 72 Bromfenac ophthalmic solution (prescription topical NSAID; Bronuck) Reduced anterior-segment inflammation and ocular pain after cataract surgery
B 72 Phacoemulsification with intraocular-lens implantation (prescription cataract surgery) Reduced recurrent falls, fall rate, and fracture risk in visually impaired older women
B 72 Daily-wear reusable soft contact lenses that are cleaned and stored for reuse Higher incidence of Acanthamoeba keratitis, a form of microbial keratitis, than with daily disposable lenses
B 71 Olopatadine hydrochloride ophthalmic solution (prescription H1 antihistamine and mast-cell stabilizer) Relief of ocular itching and redness in seasonal allergic conjunctivitis
B 70 Zinc in the AREDS and AREDS2 context Reduced risk of intermediate age-related macular degeneration progressing to advanced disease and central vision loss
B 70 Sleeping in standard soft, approved extended-wear silicone-hydrogel, or rigid contact lenses Increased microbial keratitis
B 70 Antibiotic-corticosteroid ear drops for acute otorrhea in children with tympanostomy tubes Improved otorrhea resolution and clinical cure versus oral amoxicillin-clavulanate or observation
B 69 Ketotifen fumarate ophthalmic solution (nonprescription antihistamine and mast-cell stabilizer) Relief of ocular itching and tearing from seasonal allergic conjunctivitis
B 68 Nepafenac (prescription ophthalmic NSAID; Nevanac) Prevention of macular edema and visual loss after cataract surgery in patients with diabetic retinopathy
B 68 Moxifloxacin 0.5% ophthalmic solution, a prescription fourth-generation fluoroquinolone antibiotic marketed as Vigamox Clinical cure and eradication of causative bacteria in bacterial conjunctivitis
B 68 Levofloxacin 0.5% ophthalmic solution, a prescription fluoroquinolone antibiotic marketed as Cravit Clinical cure and eradication of causative organisms in bacterial conjunctivitis
B 68 Dexamethasone intravitreal implant (prescription corticosteroid implant; Ozurdex) Clinically meaningful visual recovery of at least 15 letters in macular edema due to retinal vein occlusion
B 68 Riboflavin-UVA corneal collagen cross-linking (CXL, a photochemical ophthalmic procedure) Prevention of corneal protrusion or K-value progression and visual deterioration in progressive keratoconus
B 68 Intravitreal bevacizumab Noninferior 6-month vision versus aflibercept in macular edema from retinal vein occlusion
B 65 Travoprost 0.004%, a prescription ophthalmic prostaglandin F2-alpha analogue Reduction of intraocular pressure in open-angle glaucoma and ocular hypertension
B 64 Dorzolamide 2% (prescription topical carbonic anhydrase inhibitor ophthalmic solution; Trusopt) Lower intraocular pressure in open-angle glaucoma and ocular hypertension
B 62 Brinzolamide 1% (topical carbonic anhydrase inhibitor ophthalmic prescription medicine) Lower intraocular pressure in open-angle glaucoma and ocular hypertension
B 60 Vitamin A (retinol/beta-carotene) Eye health, night blindness, skin, and immunity
B 60 Maqui berry extract (Aristotelia chilensis) Improvement in dry eye and tear production
B 60 Brolucizumab (anti-VEGF-A single-chain antibody fragment, Beovu, prescription intravitreal injection) Improved vision and prevention of vision loss in neovascular age-related macular degeneration
C 59 Palmitoylethanolamide (PEA) Adjunctive support for intraocular pressure and glaucoma
C 59 Low-dose atropine 0.05% (prescription ophthalmic drops) Slowed childhood myopia progression and axial elongation
C 58 Tisochrysis lutea powder Improvement of dry-eye symptoms and tear secretion
C 58 Trehalose ophthalmic solution (cytoprotective artificial tear) Improvement of dry-eye symptoms and tear-film stability
C 58 Diquafosol sodium ophthalmic solution (Diquas, prescription medicine) Improvement of dry-eye symptoms by increasing fluid and mucin secretion
C 57 Grape-skin enzymatic fermented extract (KL-GEFE) Improvement of dry eye and tear-film measures
C 57 Rebamipide eye drops (Rebaeye, prescription) Improvement of dry-eye symptoms and corneoconjunctival epithelial damage by promoting mucin secretion
C 56 Centella asiatica extract powder Maintenance of macular pigment density and eye health
C 56 Pilocarpine hydrochloride 1.25% ophthalmic solution (muscarinic agonist, VUITY, prescription eye drops) Improved near vision for several hours after dosing in adults with presbyopia
C 55 Astaxanthin (astaxanthin, Haematococcus extract) eye fatigue, skin health, and antioxidant effects
C 55 Sodium hyaluronate ophthalmic solution (artificial tears) Improvement of dry-eye symptoms and tear-film stability
C 55 Repeated low-level red-light therapy (RLRL, desktop ophthalmic light-treatment device) Slowed axial elongation and refractive progression in children with myopia
C 55 High-add multifocal soft contact lenses (peripheral-add optical lenses with +2.50 D add power) Slowed refractive progression and axial elongation in childhood myopia
C 54 Saffron extract Visual function and contrast sensitivity in age-related macular degeneration
C 54 Carboxymethylcellulose sodium eye drops (CMC, Refresh, nonprescription) Improvement of dry-eye symptoms, irritation, and tear-film instability
C 54 Daily digital screen time Higher myopia risk in children and adolescents
C 54 Immediate sequential bilateral cataract surgery Achievement of refractive target versus delayed sequential surgery
C 52 Cyclosporine ophthalmic emulsion (Restasis, prescription medicine) Improved tear production and symptoms in inflammatory dry eye
C 52 DIMS defocus spectacle lenses (Defocus Incorporated Multiple Segments; MiyoSmart; a peripheral myopic-defocus optical medical device) Reduced two-year refractive progression and axial elongation in children with myopia
C 50 Lutein and zeaxanthin macular health and eye health
C 50 Vitamin D3 (cholecalciferol, fat-soluble vitamin supplement) Improvement in OSDI, tear-film stability, and tear secretion in patients with dry eye and vitamin D deficiency
C 50 Orthokeratology overnight corneal-reshaping lens Slower childhood myopia progression and axial elongation
C 50 Lifitegrast 5% ophthalmic solution, an LFA-1 antagonist Improved eye-dryness and ocular-discomfort symptoms
C 50 Raw vegetable salad eaten with 0, 75, or 150 g scrambled whole egg Increased 10-hour plasma TRL AUC for total and individual carotenoids
C 50 Pre-moistened eyelid-cleansing wipe containing aloe, purslane extract, panthenol, and surfactants Reduction of blepharitis-associated ocular symptoms
C 50 A workplace hearing-conservation program with sustained use of hearing protection Reduced standard hearing-threshold shifts
C 50 A photocatalytic micro-mist desktop humidifier operated near the face during a visual display terminal task Longer noninvasive tear-film breakup time after one hour of screen work
C 50 Glasses with pads containing ethanol extracts of four medicinal plants Reduced OSDI symptoms in mild dry eye
C 49 Persimmon-leaf ethanolic extract Improvement of dry eye
C 49 Nicotinamide or niacinamide (high-dose oral supplement) Improved retinal ganglion-cell function and short-term visual function in glaucoma during intraocular-pressure-lowering treatment
C 47 Purple corn cob and husk extract powder Improvement of dry eyes
C 46 Bilberry extract (anthocyanins/anthocyanosides) eye fatigue, eye health, vision/night vision, and dry-eye-related claims
C 46 Meso-zeaxanthin Increased macular pigment, improved contrast sensitivity, and reduced glare disability
C 46 Mirtogenol combination (Mirtoselect bilberry plus Pycnogenol) Lower intraocular pressure and slowed glaucoma progression
C 46 Tafluprost (prostaglandin F2 alpha analogue eye drops, Taflotan, prescription drug) Slowing progression of glaucomatous visual-field loss beyond lowering intraocular pressure
C 46 Pegcetacoplan 15 mg intravitreal injection Slowed geographic atrophy lesion enlargement in nonexudative age-related macular degeneration
C 46 Avacincaptad pegol (Izervay, intravitreal injection) Slowed geographic atrophy lesion enlargement in age-related macular degeneration
C 46 Raw vegetable salad with dressings containing 0, 2, 4, 8, or 32 g soybean oil Increased postprandial chylomicron carotenoid AUC and peak concentration
C 46 A unilateral inferior punctal plug in prostaglandin-treated glaucoma patients Improvement in ocular-surface symptoms and tear-film measures
C 46 Prescription-matched free eyeglasses delivered directly at school Improved end-of-year mathematics scores compared with prescription-only access
C 46 A botanical formula containing lutein ester, zeaxanthin, blackcurrant, chrysanthemum, and goji berry extracts Reduced digital eye fatigue in adults using video displays
C 45 Perilla leaf extract Eye-fatigue relief
C 45 Nicotinamide (niacinamide, the amide form of vitamin B3) High-dose supplementation to slow long-term visual-field loss in open-angle or normal-tension glaucoma
C 44 Sea buckthorn oil (Hippophae rhamnoides) Dry-eye symptoms and tear-film improvement
C 44 Valacyclovir (prescription guanosine antiviral prodrug; Valtrex) Prevention of recurrent keratitis and iritis with one year of suppressive therapy after herpes zoster ophthalmicus
C 43 Goji berry (wolfberry, Lycium barbarum/goji berry) Eye, fatigue, immunity, antioxidant
C 43 Gardenia-derived crocetin Improvement of eye fatigue and accommodation
C 42 Dried Tetraselmis chuii powder Improvement of dry eye and tear secretion
C 40 Blackcurrant anthocyanins VDT-related eye fatigue and dark adaptation
C 40 Cyanidin-3-glucoside-rich black soybean seed-coat extract Eye fatigue and accommodative function
C 40 Brimonidine ophthalmic solution (alpha-2 agonist eye drop, Alphagan, prescription) Neuroprotection beyond intraocular-pressure lowering that inhibits visual-field progression in normal-tension glaucoma
C 40 Saffron extract (Crocus sativus; crocin-containing botanical extract and supplement) Lowering intraocular pressure and inhibiting progression when added to existing eye-drop treatment for primary open-angle glaucoma
C 40 LipiFlow thermal pulsation (ophthalmic medical-device procedure) Improvement of symptoms and tear-film measures in meibomian-gland-dysfunction dry eye
D 36 Eyelid warming mask (a moist-heat or steam non-drug eye-care product) Improved dryness, foreign-body sensation, and tear-film stability in evaporative dry eye caused by meibomian gland dysfunction
D 35 Bates-type eye exercises (device-free vision training) Reduced myopic refractive power and permanently restored unaided vision through repeated training
D 35 Intense pulsed light therapy (IPL, ophthalmic procedure) Improved tear-film measures and symptoms in dry eye due to meibomian gland dysfunction
D 34 Citicoline or CDP-choline (phospholipid precursor, supplement and medicine in some countries) Adjunctive inhibition of glaucomatous visual-field progression during pressure-lowering treatment
D 34 Femtosecond laser-assisted cataract surgery (FLACS) Superior three-month uncorrected distance visual acuity versus phacoemulsification
D 32 Omega-3 (EPA/DHA) Dry eye disease
D 30 Yellow-lens night-driving glasses Faster pedestrian detection under headlight glare
D 30 Rinsing, cleaning, or storing contact lenses in tap water Safe use without increased Acanthamoeba or fungal keratitis
D 30 Air-travel earplugs containing a pressure-regulating filter Prevention of ear pain and middle-ear barotrauma during aircraft descent
D 30 Routine water precautions after pediatric tympanostomy tubes, using earplugs during bathing and swimming or avoiding swimming Prevention of tympanostomy-tube otorrhea within one year
D 28 Pirenoxine eye drops (Kary Uni or Catalin, prescription) Slowing progression of early senile cataract
D 28 Looking about 20 feet away for 20 seconds every 20 minutes Relief of digital eye strain and dry-eye symptoms
D 28 Eye patching for simple corneal abrasion Faster healing and less pain
D 28 Tea tree oil eyelid scrub Symptom improvement in Demodex blepharitis
D 27 Marine omega-3 EPA and DHA from fish-oil supplements Improvement of dry-eye symptoms and tear-film status
D 25 Lutein and zeaxanthin (xanthophyll carotenoid supplements) Prevention of age-related cataract progression, moderate vision loss, and cataract surgery
D 24 N-acetylcarnosine eye drops (NAC eye drops, Can-C) Reversal or slowed progression of age-related cataract and restoration of vision
D 24 Pinhole glasses (non-drug multiple-aperture optical vision-training product) Permanent reduction of myopic refractive error and restoration of unaided vision through continued wear
D 23 Ginkgo biloba extract (flavonoid- and terpene-lactone supplement or herbal medicine) Lower intraocular pressure and slower visual-field loss in normal-tension glaucoma
D 22 Omega-3 fatty acids (EPA and DHA; fish-oil supplement) Suppression of age-related macular degeneration progression and vision loss when added to an AREDS formulation
F 10 Blue-light filtering spectacles (non-drug optical filters) Relief of eye strain and dry eye and protection of the retina in digital-screen users
F 10 Vitamin C (oral 500 mg/day supplement) Long-term prevention of age-related cataract onset, progression, and cataract surgery
F 8 High-dose vitamin E (alpha-tocopherol 400 to 600 IU, a fat-soluble antioxidant vitamin supplement and ingredient in some nonprescription products) Reduced incidence and progression of age-related cataract and lower risk of cataract surgery
? score not listed Chrysanthemum flower (Chrysanthemum indicum) Eye-fatigue relief and vision protection
? score not listed Eyebright (Euphrasia officinalis) Eye-fatigue relief and vision protection
? score not listed Bromelain (vitreous-floater efficacy claim) Reduction of vitreous floaters and opacities
? score not listed Self-instillation of 100% castor oil (ricinoleic-acid-rich plant oil; nonsterile general-purpose oil) Dissolution or reversal of age-related cataract with restored vision after ocular instillation
? score not listed Whole carrots or carrot juice (Daucus carota) Improved vision in people with normal sight and no vitamin A deficiency
? score not listed Whole bell peppers and sweet peppers Improved eye fatigue and visual function