CHAMGAP
VERIFIEDPassed the Codex final verification and publication gate. Evidence-verification cutoff: 2026-07-11. AI was used for research and drafting; the existence of all 2 cited sources was verified at the original page, followed by blind grading, adversarial audit, and build validation. Methodology v1.0.
Verdict No. 260 · Search date 2026-07-11 · Methodology v1.0

Perilla leaf extract,
does it really help with Eye-fatigue relief?

30-Second Summary
C
Evidence Grade C · 45 · Safety acceptable
Short-term accommodation markers show a signal, but independent replication is insufficient
What the
research shows
Perilla leaf aqueous extract improved visual-function measures such as near points and accommodation after smartphone VDT work in a small placebo-controlled study of roughly 30 participants and one week. The paper is internally inconsistent, stating both 30 participants total and 30 per group, so a definitive total is not asserted. The grade is C because the 2017 reports share investigators, may overlap in samples, and focus on accommodative surrogates.
What the
ads claim
Advertising presents 'ciliary muscle relaxation,' 'focus recovery,' and 'smartphone eye-fatigue relief' as a single established effect. The human data directly concern short-term accommodation before and after a VDT challenge, not long-term vision preservation or prevention of eye disease.
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Useful facts when choosing a product

  • The research formulation was a perilla leaf aqueous extract at 500 mg/day.
  • The assessment period was limited to a single intake or one week.
  • Main outcomes were surrogates such as near-point accommodation, near point of convergence, accommodative power, and accommodative facility.
  • The research received a government industrial-support grant, and no independent large replication was identified.
ID

Chamgap Semantic Classification Code

Candidate index · review held

S.perilla-leaf-extract.UNK.eye-fatigue-relief.relieve.placebo

Supplements and nutraceuticals > Perilla leaf extract > Unknown > Eye-fatigue relief > Symptom-relief claim > Placebo

An automated migration candidate, not an issued permanent code; exact claim scope remains under review. This machine-generated migration candidate helps retrieval but is not a permanent assignment. The original verdict ID and URL remain authoritative.

Download semantic index (JSON) · Codebook v1

Gap Measurement · Verdict 260 · C 45
What advertising claims
What independent, higher-quality research supports
△ GAP
01

What the research actually shows

The Kim 2017 study used perilla leaf aqueous extract at 500 mg/day for one week before a two-hour smartphone VDT challenge and reported improved near-point accommodation. Because the paper states both 30 participants total and 30 per group, the definitive total is not asserted and the study is described as roughly 30 participants. The related Jeong 2017 report evaluated similar visual-function measures, but the same-year reports share investigators and similar protocols and may overlap in samples, so they were not counted as independent replications.

02

Why this is classified as C (45)

Direct placebo-controlled human data exist, but the evidence is small, brief, surrogate-centered, and potentially overlapping in investigators and samples, resulting in C with 45 points.

Counterpoint. A short-term signal for reducing deterioration in accommodation after VDT work remains. This judgment does not include long-term vision protection or prevention of eye disease.

Rejudgment record. Reassessment (cross-check reflected) — A positive roughly 30-person, one-week placebo-controlled signal, but internally inconsistent sample reporting, overlapping 2017 investigators and possibly samples, accommodative surrogates, and no independent replication

✓

Cross-check — AI research and Codex final gate

AI was used for research and drafting. Blind grading, adversarial audit, and the methodology boundary rules were then reapplied before Codex performed the final evidence, grade, copy, and build checks. If a grade cannot be narrowed, both evidence positions and their reasons are published.
03

Evidence Table

StudyDesignSampleFundingEndpointResultWeight
Kim J et al. 2017Randomized double-blind placebo-controlled trial30Support program funded by the Korean Ministry of Trade, Industry and EnergyNear-point accommodation after a two-hour VDT challengeOne week of perilla leaf aqueous extract at 500 mg/day improved near-point accommodation versus placebo after the VDT challenge.Key
Jeong KI et al. 2017Placebo-controlled crossover-style visual-function study30Government and research-institute linked; details unknownNear point of convergence, accommodative power, and accommodative facilityFavorable changes followed extract intake, with possible sample overlap with related research.Supportive
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Receipt — 2 References

All 2 cited sources were verified for existence at the original page (as of 2026-07-11).

Kim J, Choi H, Kim MR, et al. Amelioration of Visual Display Terminal-induced Ocular Fatigue by Aqueous Extracts of Perilla frutescens var. acuta. Journal of Food and Nutrition Research. 2017;5(8):553-561. DOI: 10.12691/jfnr-5-8-4.
checked
Jeong KI, Kim J, Choi CY, Yoo GC. Effects of Perilla frutescens var. acuta Aqueous Extract on the Visual Function. Korean J Vis Sci. 2017;19(3):283-291. DOI: 10.17337/JMBI.2017.19.3.283.
checked
Research and draft: AI used · Cross-check: blind grading and adversarial audit
Final verification and publication gate: Codex · Evidence date: 2026-07-11 · Corrections: none
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Cite this verdict

Perilla leaf extract x eye-fatigue relief Evidence Grade C card
[Chamgap] Perilla leaf extract x eye-fatigue relief — Evidence Grade C·45. 2 cited sources checked. Source: https://chamgap.com/en/verdicts/eye/perilla-leaf-eye-fatigue/ · CC BY 4.0

CC BY 4.0 — free to use with attribution; do not distort grades, numbers, or verdict meaning.

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What this document does and does not do

Chamgap is an information source. It reports what research has and has not confirmed; it does not tell readers what to take or buy. That decision belongs to readers and, when needed, medical or legal professionals. This verdict reflects literature available up to the search date and may change as new research appears. Nothing here is medical advice.
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