CHAMGAP
VERIFIEDPassed the Codex final verification and publication gate. Evidence-verification cutoff: 2026-07-11. AI was used for research and drafting; the existence of all 3 cited sources was verified at the original page, followed by blind grading, adversarial audit, and build validation. Methodology v1.0.
Verdict No. 277 · Search date 2026-07-11 · Methodology v1.0

Fadogia agrestis,
does it really help with Increased testosterone and male vitality?

30-Second Summary
?
Evidence Grade ? · Safety caution
Human efficacy trials are absent, so testosterone and vitality effects cannot be judged
What the
research shows
No human efficacy trial evaluating testosterone or male vitality was identified. The known positive signals come from hormone and sexual-behavior outcomes in male rats, so the human efficacy grade is ?.
What the
ads claim
Advertisements combine claims of testosterone boosting, libido, strength, and vitality, but no human study has directly tested them.
*

Useful facts when choosing a product

  • Positive efficacy signals come from male-rat studies, not human studies.
  • The aqueous extract used in animal research has not been shown to match the source material or standardization of marketed capsules.
  • No effective human dose or long-term human safety profile has been established.
ID

Chamgap Semantic Classification Code

Candidate index · review held

UNK.fadogia-agrestis.UNK.testosterone-and-male-vitality.increase.UNK

Unknown > Fadogia agrestis > Unknown > testosterone and male vitality > Increase claim > Unknown

An automated migration candidate, not an issued permanent code; exact claim scope remains under review. This machine-generated migration candidate helps retrieval but is not a permanent assignment. The original verdict ID and URL remain authoritative.

Download semantic index (JSON) · Codebook v1

Gap Measurement · Verdict 277 · ?
What advertising claims
What independent, higher-quality research supports
△ GAP
01

What the research actually shows

Yakubu 2005 reported increased serum testosterone and sexual behavior after five days of an aqueous stem extract in male rats. Yakubu 2008 and 2009 reported abnormal signals in testicular-function markers and liver and kidney cell-membrane integrity after 28-day repeat dosing. No human efficacy trial was identified.

02

Why this is classified as ?

Because no human efficacy literature exists, the grade is ? and the score is null regardless of the direction of preclinical evidence.

Counterpoint. A testosterone signal exists in rodents, but it cannot be converted into a human effect estimate.

Rejudgment record. New verdict — No human testosterone or vitality efficacy trial; only animal evidence is available

✓

Cross-check — AI research and Codex final gate

AI was used for research and drafting. Blind grading, adversarial audit, and the methodology boundary rules were then reapplied before Codex performed the final evidence, grade, copy, and build checks. If a grade cannot be narrowed, both evidence positions and their reasons are published.
03

Evidence Table

StudyDesignSampleFundingEndpointResultWeight
Yakubu MT et al. 2005Male-rat animal studyUnknownSerum testosterone and sexual behaviorFive-day dosing increased testosterone and selected sexual-behavior measures.Preclinical
Yakubu MT et al. 2008Twenty-eight-day repeat-dose male-rat study4UnknownBiochemical markers of testicular functionAbnormal changes related to testicular function were reported at all tested doses.Safety, preclinical
Yakubu MT et al. 2009Twenty-eight-day male-rat toxicity study4UnknownLiver and kidney enzymes and lipid peroxidationPossible compromise of hepatocyte and nephron cell-membrane integrity was reported.Safety, preclinical
§

Receipt — 3 References

All 3 cited sources were verified for existence at the original page (as of 2026-07-11).

Yakubu MT, Akanji MA, Oladiji AT. Aphrodisiac potentials of the aqueous extract of Fadogia agrestis (Schweinf. Ex Hiern) stem in male albino rats. Asian J Androl. 2005;7(4):399-404. DOI: 10.1111/j.1745-7262.2005.00052.x.
checked
Yakubu MT, Akanji MA, Oladiji AT. Effects of oral administration of aqueous extract of Fadogia agrestis (Schweinf. Ex Hiern) stem on some testicular function indices of male rats. J Ethnopharmacol. 2008;115(2):288-292. PMID: 18023305. DOI: 10.1016/j.jep.2007.10.004.
checked
Yakubu MT, Oladiji AT, Akanji MA. Mode of cellular toxicity of aqueous extract of Fadogia agrestis (Schweinf. Ex Hiern) stem in male rat liver and kidney. Hum Exp Toxicol. 2009;28(8):469-478. PMID: 19755438. DOI: 10.1177/0960327109106973.
checked
Research and draft: AI used · Cross-check: blind grading and adversarial audit
Final verification and publication gate: Codex · Evidence date: 2026-07-11 · Corrections: none
↗

Cite this verdict

Fadogia agrestis x increased testosterone and male vitality Evidence Grade ? card
[Chamgap] Fadogia agrestis x increased testosterone and male vitality — Evidence Grade ?. 3 cited sources checked. Source: https://chamgap.com/en/verdicts/mens/fadogia-agrestis-testosterone-vitality/ · CC BY 4.0

CC BY 4.0 — free to use with attribution; do not distort grades, numbers, or verdict meaning.

!

What this document does and does not do

Chamgap is an information source. It reports what research has and has not confirmed; it does not tell readers what to take or buy. That decision belongs to readers and, when needed, medical or legal professionals. This verdict reflects literature available up to the search date and may change as new research appears. Nothing here is medical advice.
↑