Supervised wall sits × lower resting SBP at 12 weeks

Required evidence, verification status and materials actually read
Item	AVerification status	BReading scope	CReview item	DCurrent findings	EWhy unverified	FRequired materials and conditions	GFurther research
1	Partly verified	Full text not readStored summary read	N01 · Evidence conditionWhat is the selected 12-week resting-SBP question?Required	The selection is lower resting SBP after 12 weeks of supervised wall sits. Preserve subclaim C and the within-group -12.9 mmHg note. Parent grade C with 54 points is separate context. S01	The selected claim, parent material and reports are distinguished and transferred from the stored summary. Detailed original material is unverified and review of existing content remains incomplete. This does not establish completed clinical review or certification.	Exact subclaim, grade/note and parent verdict	Material needed: The subclaim has no score, status or axis fields. Do not fill them with parent values. This records needed materials; no new research was executed.
2	Partly verified	Full text not readStored summary read	N02 · Evidence conditionWhich adults with hypertension participated?Required	Cohen records 77 untreated adults aged 35–65 with hypertension. S01	The selected claim, parent material and reports are distinguished and transferred from the stored summary. Detailed original material is unverified and review of existing content remains incomplete. This does not establish completed clinical review or certification.	Diagnosis, age, medication status, baseline risk and eligibility	Material needed: Exact diagnosis, baseline severity, eligibility/exclusions, sex, comorbidities and recruitment details are needed. Do not extend to treated people or other ages. This records needed materials; no new research was executed.
3	Partly verified	Full text not readStored summary read	N03 · Evidence conditionWhat was the supervised wall-sit intervention?Required	The original text records angle, intensity and supervision as parts of supervised isometric wall sits. S01	The selected claim, parent material and reports are distinguished and transferred from the stored summary. Detailed original material is unverified and review of existing content remains incomplete. This does not establish completed clinical review or certification.	Supervision, knee angle, intensity calibration, actual delivery and components	Material needed: Individual settings, supervision, actual delivery and adherence are needed. Research conditions are not new exercise instructions. This records needed materials; no new research was executed.
4	Partly verified	Full text not readStored summary read	N04 · Evidence conditionHow do initial training and maintenance differ?Required	Distinguish original initial training 3 times weekly for 12 weeks, 4 holds of 2 minutes with 2-minute seated rests, and later maintenance 1 time weekly. S01	The selected claim, parent material and reports are distinguished and transferred from the stored summary. Detailed original material is unverified and review of existing content remains incomplete. This does not establish completed clinical review or certification.	Separate attribution of initial/maintenance schedules and analyses	Material needed: Maintenance allocation, duration, denominators and detailed results are needed. Do not transfer maintenance into a minimum starting dose. This records needed materials; no new research was executed.
5	Partly verified	Full text not readStored summary read	N05 · Evidence conditionWhat were the actual comparators?Required	77 participants were assigned to 3 handgrip, wall-sit and no-exercise arms. Selected values describe wall sit versus no exercise. S01	The selected claim, parent material and reports are distinguished and transferred from the stored summary. Detailed original material is unverified and review of existing content remains incomplete. This does not establish completed clinical review or certification.	Wall sit versus no exercise and the scope of the other exercise arm	Material needed: Arm allocation, denominators, contact, expectations and usual activity are needed. Do not combine handgrip with the wall-sit intervention. This records needed materials; no new research was executed.
6	Partly verified	Full text not readStored summary read	N06 · Evidence conditionDoes complete follow-up establish endpoint denominators?Required	Preserve the original record that all 77 Cohen participants completed. S01	The selected claim, parent material and reports are distinguished and transferred from the stored summary. Detailed original material is unverified and review of existing content remains incomplete. This does not establish completed clinical review or certification.	Overall allocation/completion versus arm denominators, missing measurements and analysis rules	Material needed: Wall-sit, no-exercise and handgrip denominators, valid/missing measurements and analysis rules are needed. Completion does not establish complete measurement of every outcome. This records needed materials; no new research was executed.
7	Partly verified	Full text not readStored summary read	N07 · Evidence conditionHow was resting office SBP measured?Required	The endpoint is recorded as 12-week office resting blood pressure. S01	The selected claim, parent material and reports are distinguished and transferred from the stored summary. Detailed original material is unverified and review of existing content remains incomplete. This does not establish completed clinical review or certification.	Resting conditions, equipment, repetitions, assessor and timing	Material needed: Equipment, rest, repetitions, assessor blinding, standardization and medication/activity/time conditions are needed. Do not combine with in-exercise pressure. This records needed materials; no new research was executed.
8	Partly verified	Full text not readStored summary read	N08 · Evidence conditionWhich arms do baseline and final values describe?Required	Preserve wall sit 141.2→128.3 and no exercise 138.9→138.5 mmHg. S01	The selected claim, parent material and reports are distinguished and transferred from the stored summary. Detailed original material is unverified and review of existing content remains incomplete. This does not establish completed clinical review or certification.	Original wall-sit/no-exercise values, units and baseline/final correspondence	Material needed: Arm denominators, variance, distributions, models and CIs are needed. Calculate no new difference, change or effect. This records needed materials; no new research was executed.
9	Partly verified	Full text not readStored summary read	N09 · Evidence conditionWhat do within-group changes and P values mean?Required	Parent records give within-wall-sit -12.9 mmHg/P<.001 and no-exercise -0.4 mmHg. The selected note also describes a within-group -12.9 change. S01	The selected claim, parent material and reports are distinguished and transferred from the stored summary. Detailed original material is unverified and review of existing content remains incomplete. This does not establish completed clinical review or certification.	Within-group changes, tests, denominators and scope of estimation	Material needed: A within-group P value is not a between-group P value. Within-group CIs, variance, denominators and between-group tests are needed. This records needed materials; no new research was executed.
10	Partly verified	Full text not readStored summary read	N10 · Evidence conditionIs the historical simple difference an adjusted effect?Required	Parent -12.5 mmHg is recorded as a simple difference between changes, not an adjusted estimate. It was not calculated in this conversion. S01	The selected claim, parent material and reports are distinguished and transferred from the stored summary. Detailed original material is unverified and review of existing content remains incomplete. This does not establish completed clinical review or certification.	Original arithmetic wording versus adjusted between-group estimation	Material needed: Adjusted effects, models, exact between-group 95% CIs and P values are needed. Do not promote a historical value into a new estimate. This records needed materials; no new research was executed.
11	Unverified	Full text not readStored summary read	N11 · Evidence conditionAre endpoint hierarchy and registration verified?Required	The original leaves the exact prospective endpoint hierarchy unverified. Cohen’s evidence summary has no registration-identifier field. S01	The selected claim, parent material and reports are distinguished and transferred from the stored summary. Detailed original material is unverified and review of existing content remains incomplete. This does not establish completed clinical review or certification.	SBP/DBP, initial/maintenance, prospective 1st/2nd outcomes and changes	Material needed: Registration, protocols, SAPs, multiplicity and change history are unread. Do not fill an absent field as unregistered or not applicable. This records needed materials; no new research was executed.
12	Partly verified	Full text not readStored summary read	N12 · Evidence conditionAre randomization and assessment roles verified?Required	Cohen is recorded as a multicenter 3-arm randomized trial. S01	The selected claim, parent material and reports are distinguished and transferred from the stored summary. Detailed original material is unverified and review of existing content remains incomplete. This does not establish completed clinical review or certification.	Allocation, concealment, multicenter structure, blinding and assessment/analysis roles	Material needed: Allocation concealment, center structure, participant/assessor/analyst blinding and expectations are needed. This records needed materials; no new research was executed.
13	Unverified	Full text not readStored summary read	N13 · Evidence conditionAre between-group analysis and missing-data handling verified?Required	Preserve both complete follow-up and gaps in adjusted effects/CIs. S01	The selected claim, parent material and reports are distinguished and transferred from the stored summary. Detailed original material is unverified and review of existing content remains incomplete. This does not establish completed clinical review or certification.	Estimand, baseline adjustment, ITT/PP, repeated/missing data and sensitivity analyses	Material needed: ITT/PP, valid/excluded measurements, center/repeated-measure models, covariates, missing data and sensitivity analyses are needed. This records needed materials; no new research was executed.
14	Partly verified	Full text not readStored summary read	N14 · Evidence conditionHow do SBP and DBP results differ?Required	Distinguish the key trial’s null between-group DBP result from its SBP signal. Diastolic pressure is a separate subclaim. S01	The selected claim, parent material and reports are distinguished and transferred from the stored summary. Detailed original material is unverified and review of existing content remains incomplete. This does not establish completed clinical review or certification.	Values, denominators and prospective analysis for each pressure measure	Material needed: SBP does not substitute for DBP effects. Exact original DBP values, CIs and analyses are needed. This records needed materials; no new research was executed.
15	Partly verified	Full text not readStored summary read	N15 · Evidence conditionWhat does the separate 4-week sham trial show?Required	Decaux has 30 participants over 4 weeks with wall sit, low-intensity sham and no exercise. Preserve SBP -15.2±9.2, DBP -4.6±5.0 mmHg and P<.05 versus controls. S02	The selected claim, parent material and reports are distinguished and transferred from the stored summary. Detailed original material is unverified and review of existing content remains incomplete. This does not establish completed clinical review or certification.	Population, intensity, comparators, duration and each pressure outcome	Material needed: The variance type for ±, arm denominators, original changes/models, comparator-specific contrasts and CIs are needed. Do not turn this into the same 12-week effect or independent confirmation. This records needed materials; no new research was executed.
16	Partly verified	Full text not readStored summary read	N16 · Evidence conditionAre registration identifiers distinct from prospective materials?Required	NCT05025202 appears in Decaux’s citation. Neither evidence summary has a registration-identifier field. S02	The selected claim, parent material and reports are distinguished and transferred from the stored summary. Detailed original material is unverified and review of existing content remains incomplete. This does not establish completed clinical review or certification.	Citation identifier, absent evidence-summary field and prospective plans	Material needed: Registration timing, changes, prospective endpoints, protocols and SAPs are unread. An identifier alone does not certify prospective status or independence. This records needed materials; no new research was executed.
17	Unverified	Full text not readStored summary read	N17 · Evidence conditionAre replication and report/sample relationships verified?Required	Preserve original supportive directions across small trials and no strict upgrade to R2. S01 S02	The selected claim, parent material and reports are distinguished and transferred from the stored summary. Detailed original material is unverified and review of existing content remains incomplete. This does not establish completed clinical review or certification.	Duration, intervention, comparator, support, shared samples and related reports	Material needed: Independent confirmation under the same conditions and unique-trial/participant or replication totals remain unverified. Reports, times, arms and sheets are not new clinical totals. This records needed materials; no new research was executed.
18	Unverified	Full text not readStored summary read	N18 · Evidence conditionDoes resting pressure establish medication replacement or event prevention?Required	The original records that medication replacement and cardiovascular events were not tested. The original grade ? subclaim is separate. S01	The selected claim, parent material and reports are distinguished and transferred from the stored summary. Detailed original material is unverified and review of existing content remains incomplete. This does not establish completed clinical review or certification.	Surrogate, medication comparison, treatment replacement and cardiovascular-event boundaries	Material needed: Do not transfer SBP into medication equivalence, dose reduction/replacement, heart-attack prevention or long-term clinical effects. Create no treatment instructions. This records needed materials; no new research was executed.
19	Unverified	Full text not readStored summary read	N19 · Evidence conditionAre maintenance and long-term persistence verified?Required	Distinguish initial training 3 times weekly for 12 weeks from later maintenance 1 time weekly. S01	The selected claim, parent material and reports are distinguished and transferred from the stored summary. Detailed original material is unverified and review of existing content remains incomplete. This does not establish completed clinical review or certification.	Initial, maintenance and long-term results, populations, denominators and comparisons	Material needed: Exact maintenance/long-term effects, denominators, comparisons and data for other ages or treated people are needed. Propose no new minimum exercise dose. This records needed materials; no new research was executed.
20	Unverified	Full text not readStored summary read	N20 · Evidence conditionAre actual delivery, coactivity and adherence verified?Supplementary	Untreated adults, supervision, angle and intensity are original research conditions. S01	The selected claim, parent material and reports are distinguished and transferred from the stored summary. Detailed original material is unverified and review of existing content remains incomplete. This does not establish completed clinical review or certification.	Concurrent exercise, medication/lifestyle changes, supervision, delivery and data attribution	Material needed: Arm-specific coactivity/changes, actual training, supervision and adherence are needed. Give no personal exercise or medication policy. This records needed materials; no new research was executed.
21	Partly verified	Full text not readStored summary read	N21 · Evidence conditionWhat are Cohen’s public funding and COI declarations?Required	Preserve Cohen’s Colombian Ministry of Science/Colciencias support and declaration of no COI. S01	The selected claim, parent material and reports are distinguished and transferred from the stored summary. Detailed original material is unverified and review of existing content remains incomplete. This does not establish completed clinical review or certification.	Funding, product support, employed authors, analysis/publication roles and COI	Material needed: Original support/product, employed-author, analysis/publication-control and declaration materials are unread. Parent independent-funding wording is not new certification. This records needed materials; no new research was executed.
22	Unverified	Full text not readStored summary read	N22 · Evidence conditionIs Decaux’s funding verified?Required	Decaux’s original record states funding information was not provided. S02	The selected claim, parent material and reports are distinguished and transferred from the stored summary. Detailed original material is unverified and review of existing content remains incomplete. This does not establish completed clinical review or certification.	Separate funding, support, employed-author and interest materials	Material needed: There is no material to fill this as no funding, independent support, no employed authors or no COI. This records needed materials; no new research was executed.
23	Partly verified	Full text not readStored summary read	N23 · Evidence conditionDo 0 reported adverse events guarantee safety?Supplementary	Preserve all 77 key-trial participants completed and 0 reported adverse events. This is a limited supervised sample. S01	The selected claim, parent material and reports are distinguished and transferred from the stored summary. Detailed original material is unverified and review of existing content remains incomplete. This does not establish completed clinical review or certification.	Harm definitions, collection, arm exposure/denominators, discontinuation and missingness	Material needed: Collection, arm exposure/denominators, severity, missingness, discontinuation and long-term harms are needed. Do not turn 0 into new safety certification. This records needed materials; no new research was executed.
24	Partly verified	Full text not readStored summary read	N24 · Evidence conditionAre acute and longer-term resting pressure the same?Supplementary	Parent records mean 196/112 mmHg during a separate acute 90° hold. This is not the 12-week resting value. S01 S02	The selected claim, parent material and reports are distinguished and transferred from the stored summary. Detailed original material is unverified and review of existing content remains incomplete. This does not establish completed clinical review or certification.	Acute holds, resting results, bibliography, population and denominators	Material needed: That acute study’s bibliography, population, denominators and measurement/exposure details are not linked. Do not borrow the other trials’ denominators or create a hypothetical report. This records needed materials; no new research was executed.
25	Unverified	Full text not readStored summary read	N25 · Evidence conditionAre long-term and vulnerable-population harms verified?Supplementary	Preserve parent caution and the acute/resting timing distinction. Give no new exercise, breathing, medication reduction/replacement or treatment instructions. S01 S02	The selected claim, parent material and reports are distinguished and transferred from the stored summary. Detailed original material is unverified and review of existing content remains incomplete. This does not establish completed clinical review or certification.	Supervision, exposure, vulnerable populations, concurrent factors and long-term harms	Material needed: Population/exposure-specific long-term harms, alternative causes and discontinuation materials are needed. Do not extend a small supervised sample into safety certification for other populations or unsupervised settings. This records needed materials; no new research was executed.
26	Partly verified	Full text not readStored summary read	N26 · Evidence conditionHow are original verdicts, dates and corrections preserved?Required	Preserve parent grade C with 54 points, both languages, axes, 2026-09-07, empty corrections and deliberation string, selected C/note and absent subclaim score/status/axes. S01 S02	The selected claim, parent material and reports are distinguished and transferred from the stored summary. Detailed original material is unverified and review of existing content remains incomplete. This does not establish completed clinical review or certification.	Parent/subclaim grades, scores, axes, both languages, dates and absent values	Material needed: Historical key/sham, funding and acute-verification wording is not current review or clinical certification. Create no new grades, effects or hypothetical numbers. This records needed materials; no new research was executed.
27	Partly verified	Full text not readStored summary read	N27 · Evidence conditionWhat material was actually read?Required	The complete stored summary and bibliography were used. Distinguish reading the stored summary from unread external material. S01 S02	The selected claim, parent material and reports are distinguished and transferred from the stored summary. Detailed original material is unverified and review of existing content remains incomplete. This does not establish completed clinical review or certification.	Report/material links and paper, registration, plan and support states	Material needed: External papers, registration, protocols, SAPs, support and acute originals are unread; access was not attempted. Links or historical verification do not establish current reading. This records needed materials; no new research was executed.

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27 itemsWhat the statuses mean

Assessment scope

Stored-material review date: Not recorded
Original evidence cut-off: 2026-09-07
Scope actually checked: Existing review summaries and stored records of methodological application. Full papers, supplements, registrations, plans and original data were not read.
What the dates mean: This is the date the stored materials were checked, not the date of a new search of the clinical literature.
Population: Cohen records 77 untreated adults aged 35–65 with hypertension, all completed. Arm denominators, diagnosis/baseline severity, eligibility/exclusions and measurement completeness are unverified. Decaux has a separate 30 participants; counts are not added.
Ingredient, formulation and route: Knee angle, intensity calibration and supervision belong to the original supervised isometric wall-sit conditions. Exact settings, actual delivery and adherence are unverified. This sheet describes research records and creates no personal exercise, breathing or treatment instructions.
Dose: Distinguish original initial training 3 times weekly for 12 weeks, 4 holds of 2 minutes with 2-minute seated rests, and later maintenance 1 time weekly. Maintenance allocation, denominators and exact results are unverified. 1 time weekly is not treated as an adequate starting dose.
Comparator: Within Cohen’s 3 handgrip, wall-sit and no-exercise arms, the selected comparison is wall sit versus no exercise. Decaux’s 4-week wall-sit, low-intensity sham and no-exercise comparisons are separate. Arm denominators, contact, expectations, activity and exact comparator-specific contrasts are unverified.
Measured outcome: At 12 weeks, office resting SBP is 141.2→128.3 with wall sits versus 138.9→138.5 mmHg with no exercise. Distinguish original within-group changes -12.9/P<.001 and -0.4 from the historical simple difference -12.5. That simple difference is not an adjusted estimate; exact between-group 95% CIs, model and prospective hierarchy are unverified. The null between-group DBP result is separate.
Duration: Initial 12 weeks and later maintenance, Decaux 4 weeks, and mean 196/112 mmHg during a separate acute 90° hold refer to different times. The acute study bibliography, population and denominators are not linked. Do not extend this to long-term effects, treated people, other ages, medication replacement or cardiovascular events.
Questions outside this scope: Transferring within-group changes/P or a historical simple difference into adjusted between-group effects/CIs; Transferring later once-weekly maintenance into a minimum starting dose; Combining resting SBP, DBP and acute in-exercise pressure as one result; Extending a blood-pressure surrogate to medication equivalence, dose reduction/replacement or cardiovascular-event prevention; Adding arms, outcomes, maintenance phases, related reports or sheets into new unique-trial/participant or independent-replication totals; Using original grades, public funding, COI declarations or 0 reported adverse events as new verdicts or independence/safety certification; Creating new numbers, effects, CIs, grades or exercise, breathing, medication reduction/replacement or treatment instructions

Evidence and sources

The links below lead to the sources. A link alone does not mean the original source was read or its latest publication status verified.

S01 · Cohen DD, Aroca-Martinez G, Carreño-Robayo J, et al. Reductions in systolic blood pressure achieved by hypertensives with three isometric training sessions per week are maintained with a single session per week. J Clin Hypertens. 2023;25(4):380-387. PMID: 36965163. PMCID: PMC10085809. DOI: 10.1111/jch.14621.

PubMed

Material type: Multicenter three-arm randomized trial
Materials actually read: Stored summary read; external abstracts, full texts, registration, protocols, SAPs and support disclosures unread
Findings recorded in the stored summary: SBP 141.2 to 128.3 vs 138.9 to 138.5 mmHg; DBP between-group null
Record level: Stored summary directly related to the selected question. Preserve 77 participants all completed, 12-week resting SBP 141.2→128.3 with wall sits versus 138.9→138.5 mmHg with no exercise, within-group -12.9/P<.001 versus -0.4. Historical simple -12.5 is not an adjusted effect. Arm denominators, variance, exact between-group 95% CIs and prospective hierarchy are unverified. Null between-group DBP, maintenance and 0 reported adverse events have separate contexts.
Study overlap and independent replication: Cohen and Decaux have separate preserved bibliographies; the parent and 3 subclaim questions share the same reports. Intervention, comparator, duration and support are not certified identical across the 12-week no-exercise and 4-week sham comparisons. Arms, repeated measures, maintenance, reports and sheets are not counted as new unique-trial/participant or independent-replication totals. An unidentified acute safety description does not create a hypothetical report.

Public availability, access and reading status by material
Material	Public availability	Access status	Actually read	Notes
Stored existing review summary	Preserved copy of the complete parent-verdict stored summary	Stored summary	Summary read	Preserve original PubMed URL, PMID 36965163, DOI 10.1111/jch.14621, PMCID PMC10085809 and bibliography. The evidence summary has no registration-identifier field. No registration identifier is recorded in the citation either. An absent field does not establish no registration; no new identifier/URL, prospective status or external reading is inferred.
External paper	Original bibliographic link or needed material; external public availability/access status unverified	Unread; access not attempted	Not read	Preserve original PubMed URL, PMID 36965163, DOI 10.1111/jch.14621, PMCID PMC10085809 and bibliography. The evidence summary has no registration-identifier field. No registration identifier is recorded in the citation either. An absent field does not establish no registration; no new identifier/URL, prospective status or external reading is inferred.
Registration material	Original bibliographic link or needed material; external public availability/access status unverified	Unread; access not attempted	Not read	Preserve original PubMed URL, PMID 36965163, DOI 10.1111/jch.14621, PMCID PMC10085809 and bibliography. The evidence summary has no registration-identifier field. No registration identifier is recorded in the citation either. An absent field does not establish no registration; no new identifier/URL, prospective status or external reading is inferred.
Protocol	Original bibliographic link or needed material; external public availability/access status unverified	Unread; access not attempted	Not read	Preserve original PubMed URL, PMID 36965163, DOI 10.1111/jch.14621, PMCID PMC10085809 and bibliography. The evidence summary has no registration-identifier field. No registration identifier is recorded in the citation either. An absent field does not establish no registration; no new identifier/URL, prospective status or external reading is inferred.
Statistical analysis plan	Original bibliographic link or needed material; external public availability/access status unverified	Unread; access not attempted	Not read	Preserve original PubMed URL, PMID 36965163, DOI 10.1111/jch.14621, PMCID PMC10085809 and bibliography. The evidence summary has no registration-identifier field. No registration identifier is recorded in the citation either. An absent field does not establish no registration; no new identifier/URL, prospective status or external reading is inferred.
Funding, product-support and COI material	Original bibliographic link or needed material; external public availability/access status unverified	Unread; access not attempted	Not read	Preserve original PubMed URL, PMID 36965163, DOI 10.1111/jch.14621, PMCID PMC10085809 and bibliography. The evidence summary has no registration-identifier field. No registration identifier is recorded in the citation either. An absent field does not establish no registration; no new identifier/URL, prospective status or external reading is inferred.

S02 · Decaux A et al. Blood pressure and cardiac autonomic adaptations to isometric exercise training: A randomized sham-controlled study. Physiol Rep. 2022;10(2):e15112. PMID: 35083878. PMCID: PMC8792514. DOI: 10.14814/phy2.15112. NCT05025202.

PubMed

Material type: Randomized wall-sit, low-intensity sham, and no-exercise trial
Materials actually read: Stored summary read; external abstracts, full texts, registration, protocols, SAPs and support disclosures unread
Findings recorded in the stored summary: SBP -15.2±9.2 and DBP -4.6±5.0 mmHg; P<.05 vs controls
Record level: Separate 30-participant, 4-week wall-sit/low-intensity sham/no-exercise report. Preserve SBP -15.2±9.2, DBP -4.6±5.0 mmHg and P<.05 versus controls. The meaning of ±, arm denominators, comparator-specific contrasts, effects/CIs and prospective hierarchy are unverified. This is not converted into the same 12-week effect or strict independent confirmation.
Study overlap and independent replication: Cohen and Decaux have separate preserved bibliographies; the parent and 3 subclaim questions share the same reports. Intervention, comparator, duration and support are not certified identical across the 12-week no-exercise and 4-week sham comparisons. Arms, repeated measures, maintenance, reports and sheets are not counted as new unique-trial/participant or independent-replication totals. An unidentified acute safety description does not create a hypothetical report.

Public availability, access and reading status by material
Material	Public availability	Access status	Actually read	Notes
Stored existing review summary	Preserved copy of the complete parent-verdict stored summary	Stored summary	Summary read	Preserve original PubMed URL, PMID 35083878, DOI 10.14814/phy2.15112, PMCID PMC8792514 and bibliography. The evidence summary has no registration-identifier field. NCT05025202 is recorded only in the citation. An absent field does not establish no registration; no new identifier/URL, prospective status or external reading is inferred.
External paper	Original bibliographic link or needed material; external public availability/access status unverified	Unread; access not attempted	Not read	Preserve original PubMed URL, PMID 35083878, DOI 10.14814/phy2.15112, PMCID PMC8792514 and bibliography. The evidence summary has no registration-identifier field. NCT05025202 is recorded only in the citation. An absent field does not establish no registration; no new identifier/URL, prospective status or external reading is inferred.
Registration material	Original bibliographic link or needed material; external public availability/access status unverified	Unread; access not attempted	Not read	Preserve original PubMed URL, PMID 35083878, DOI 10.14814/phy2.15112, PMCID PMC8792514 and bibliography. The evidence summary has no registration-identifier field. NCT05025202 is recorded only in the citation. An absent field does not establish no registration; no new identifier/URL, prospective status or external reading is inferred.
Protocol	Original bibliographic link or needed material; external public availability/access status unverified	Unread; access not attempted	Not read	Preserve original PubMed URL, PMID 35083878, DOI 10.14814/phy2.15112, PMCID PMC8792514 and bibliography. The evidence summary has no registration-identifier field. NCT05025202 is recorded only in the citation. An absent field does not establish no registration; no new identifier/URL, prospective status or external reading is inferred.
Statistical analysis plan	Original bibliographic link or needed material; external public availability/access status unverified	Unread; access not attempted	Not read	Preserve original PubMed URL, PMID 35083878, DOI 10.14814/phy2.15112, PMCID PMC8792514 and bibliography. The evidence summary has no registration-identifier field. NCT05025202 is recorded only in the citation. An absent field does not establish no registration; no new identifier/URL, prospective status or external reading is inferred.
Funding, product-support and COI material	Original bibliographic link or needed material; external public availability/access status unverified	Unread; access not attempted	Not read	Preserve original PubMed URL, PMID 35083878, DOI 10.14814/phy2.15112, PMCID PMC8792514 and bibliography. The evidence summary has no registration-identifier field. NCT05025202 is recorded only in the citation. An absent field does not establish no registration; no new identifier/URL, prospective status or external reading is inferred.

Report counts versus independent study counts

Cohen and Decaux have separate preserved bibliographies; the parent and 3 subclaim questions share the same reports. Intervention, comparator, duration and support are not certified identical across the 12-week no-exercise and 4-week sham comparisons. Arms, repeated measures, maintenance, reports and sheets are not counted as new unique-trial/participant or independent-replication totals. An unidentified acute safety description does not create a hypothetical report.

Review criteria

Version 1.0 · Criteria record date 2026-10-06. These are Chamgap's own application conditions, informed by the referenced methods. They do not constitute official assessment-tool certification or a new efficacy score.

N01 · What is the selected 12-week resting-SBP question?

Required materials and conditions: Exact subclaim, grade/note and parent verdict
Conditions for verification: Material for Exact subclaim, grade/note and parent verdict must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.
Requirement and applicability: Required
Application exceptions: Preserve selected subclaim C and its within-group -12.9 mmHg note. Distinguish absent subclaim score/status/axes from parent grade C with 54 points. Within-group changes or a historical simple difference are not adjusted between-group effects; maintenance is not a minimum starting dose. Create no new numbers, CIs, totals, grades, independence/safety certification or exercise, breathing, medication or treatment instructions.
Why this condition is needed: This condition connects Exact subclaim, grade/note and parent verdict with selected 12-week resting systolic pressure, within- versus between-group comparisons, initial training versus maintenance, and measurement, denominator, support and harm boundaries.
Referenced methods: Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.

N02 · Which adults with hypertension participated?

Required materials and conditions: Diagnosis, age, medication status, baseline risk and eligibility
Conditions for verification: Material for Diagnosis, age, medication status, baseline risk and eligibility must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.
Requirement and applicability: Required
Application exceptions: Preserve selected subclaim C and its within-group -12.9 mmHg note. Distinguish absent subclaim score/status/axes from parent grade C with 54 points. Within-group changes or a historical simple difference are not adjusted between-group effects; maintenance is not a minimum starting dose. Create no new numbers, CIs, totals, grades, independence/safety certification or exercise, breathing, medication or treatment instructions.
Why this condition is needed: This condition connects Diagnosis, age, medication status, baseline risk and eligibility with selected 12-week resting systolic pressure, within- versus between-group comparisons, initial training versus maintenance, and measurement, denominator, support and harm boundaries.
Referenced methods: Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.

N03 · What was the supervised wall-sit intervention?

Required materials and conditions: Supervision, knee angle, intensity calibration, actual delivery and components
Conditions for verification: Material for Supervision, knee angle, intensity calibration, actual delivery and components must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.
Requirement and applicability: Required
Application exceptions: Preserve selected subclaim C and its within-group -12.9 mmHg note. Distinguish absent subclaim score/status/axes from parent grade C with 54 points. Within-group changes or a historical simple difference are not adjusted between-group effects; maintenance is not a minimum starting dose. Create no new numbers, CIs, totals, grades, independence/safety certification or exercise, breathing, medication or treatment instructions.
Why this condition is needed: This condition connects Supervision, knee angle, intensity calibration, actual delivery and components with selected 12-week resting systolic pressure, within- versus between-group comparisons, initial training versus maintenance, and measurement, denominator, support and harm boundaries.
Referenced methods: Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.

N04 · How do initial training and maintenance differ?

Required materials and conditions: Separate attribution of initial/maintenance schedules and analyses
Conditions for verification: Material for Separate attribution of initial/maintenance schedules and analyses must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.
Requirement and applicability: Required
Application exceptions: Preserve selected subclaim C and its within-group -12.9 mmHg note. Distinguish absent subclaim score/status/axes from parent grade C with 54 points. Within-group changes or a historical simple difference are not adjusted between-group effects; maintenance is not a minimum starting dose. Create no new numbers, CIs, totals, grades, independence/safety certification or exercise, breathing, medication or treatment instructions.
Why this condition is needed: This condition connects Separate attribution of initial/maintenance schedules and analyses with selected 12-week resting systolic pressure, within- versus between-group comparisons, initial training versus maintenance, and measurement, denominator, support and harm boundaries.
Referenced methods: Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.

N05 · What were the actual comparators?

Required materials and conditions: Wall sit versus no exercise and the scope of the other exercise arm
Conditions for verification: Material for Wall sit versus no exercise and the scope of the other exercise arm must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.
Requirement and applicability: Required
Application exceptions: Preserve selected subclaim C and its within-group -12.9 mmHg note. Distinguish absent subclaim score/status/axes from parent grade C with 54 points. Within-group changes or a historical simple difference are not adjusted between-group effects; maintenance is not a minimum starting dose. Create no new numbers, CIs, totals, grades, independence/safety certification or exercise, breathing, medication or treatment instructions.
Why this condition is needed: This condition connects Wall sit versus no exercise and the scope of the other exercise arm with selected 12-week resting systolic pressure, within- versus between-group comparisons, initial training versus maintenance, and measurement, denominator, support and harm boundaries.
Referenced methods: Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.

N06 · Does complete follow-up establish endpoint denominators?

Required materials and conditions: Overall allocation/completion versus arm denominators, missing measurements and analysis rules
Conditions for verification: Material for Overall allocation/completion versus arm denominators, missing measurements and analysis rules must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.
Requirement and applicability: Required
Application exceptions: Preserve selected subclaim C and its within-group -12.9 mmHg note. Distinguish absent subclaim score/status/axes from parent grade C with 54 points. Within-group changes or a historical simple difference are not adjusted between-group effects; maintenance is not a minimum starting dose. Create no new numbers, CIs, totals, grades, independence/safety certification or exercise, breathing, medication or treatment instructions.
Why this condition is needed: This condition connects Overall allocation/completion versus arm denominators, missing measurements and analysis rules with selected 12-week resting systolic pressure, within- versus between-group comparisons, initial training versus maintenance, and measurement, denominator, support and harm boundaries.
Referenced methods: Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.

N07 · How was resting office SBP measured?

Required materials and conditions: Resting conditions, equipment, repetitions, assessor and timing
Conditions for verification: Material for Resting conditions, equipment, repetitions, assessor and timing must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.
Requirement and applicability: Required
Application exceptions: Preserve selected subclaim C and its within-group -12.9 mmHg note. Distinguish absent subclaim score/status/axes from parent grade C with 54 points. Within-group changes or a historical simple difference are not adjusted between-group effects; maintenance is not a minimum starting dose. Create no new numbers, CIs, totals, grades, independence/safety certification or exercise, breathing, medication or treatment instructions.
Why this condition is needed: This condition connects Resting conditions, equipment, repetitions, assessor and timing with selected 12-week resting systolic pressure, within- versus between-group comparisons, initial training versus maintenance, and measurement, denominator, support and harm boundaries.
Referenced methods: Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.

N08 · Which arms do baseline and final values describe?

Required materials and conditions: Original wall-sit/no-exercise values, units and baseline/final correspondence
Conditions for verification: Material for Original wall-sit/no-exercise values, units and baseline/final correspondence must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.
Requirement and applicability: Required
Application exceptions: Preserve selected subclaim C and its within-group -12.9 mmHg note. Distinguish absent subclaim score/status/axes from parent grade C with 54 points. Within-group changes or a historical simple difference are not adjusted between-group effects; maintenance is not a minimum starting dose. Create no new numbers, CIs, totals, grades, independence/safety certification or exercise, breathing, medication or treatment instructions.
Why this condition is needed: This condition connects Original wall-sit/no-exercise values, units and baseline/final correspondence with selected 12-week resting systolic pressure, within- versus between-group comparisons, initial training versus maintenance, and measurement, denominator, support and harm boundaries.
Referenced methods: Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.

N09 · What do within-group changes and P values mean?

Required materials and conditions: Within-group changes, tests, denominators and scope of estimation
Conditions for verification: Material for Within-group changes, tests, denominators and scope of estimation must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.
Requirement and applicability: Required
Application exceptions: Preserve selected subclaim C and its within-group -12.9 mmHg note. Distinguish absent subclaim score/status/axes from parent grade C with 54 points. Within-group changes or a historical simple difference are not adjusted between-group effects; maintenance is not a minimum starting dose. Create no new numbers, CIs, totals, grades, independence/safety certification or exercise, breathing, medication or treatment instructions.
Why this condition is needed: This condition connects Within-group changes, tests, denominators and scope of estimation with selected 12-week resting systolic pressure, within- versus between-group comparisons, initial training versus maintenance, and measurement, denominator, support and harm boundaries.
Referenced methods: Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.

N10 · Is the historical simple difference an adjusted effect?

Required materials and conditions: Original arithmetic wording versus adjusted between-group estimation
Conditions for verification: Material for Original arithmetic wording versus adjusted between-group estimation must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.
Requirement and applicability: Required
Application exceptions: Preserve selected subclaim C and its within-group -12.9 mmHg note. Distinguish absent subclaim score/status/axes from parent grade C with 54 points. Within-group changes or a historical simple difference are not adjusted between-group effects; maintenance is not a minimum starting dose. Create no new numbers, CIs, totals, grades, independence/safety certification or exercise, breathing, medication or treatment instructions.
Why this condition is needed: This condition connects Original arithmetic wording versus adjusted between-group estimation with selected 12-week resting systolic pressure, within- versus between-group comparisons, initial training versus maintenance, and measurement, denominator, support and harm boundaries.
Referenced methods: Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.

N11 · Are endpoint hierarchy and registration verified?

Required materials and conditions: SBP/DBP, initial/maintenance, prospective 1st/2nd outcomes and changes
Conditions for verification: Material for SBP/DBP, initial/maintenance, prospective 1st/2nd outcomes and changes must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.
Requirement and applicability: Required
Application exceptions: Preserve selected subclaim C and its within-group -12.9 mmHg note. Distinguish absent subclaim score/status/axes from parent grade C with 54 points. Within-group changes or a historical simple difference are not adjusted between-group effects; maintenance is not a minimum starting dose. Create no new numbers, CIs, totals, grades, independence/safety certification or exercise, breathing, medication or treatment instructions.
Why this condition is needed: This condition connects SBP/DBP, initial/maintenance, prospective 1st/2nd outcomes and changes with selected 12-week resting systolic pressure, within- versus between-group comparisons, initial training versus maintenance, and measurement, denominator, support and harm boundaries.
Referenced methods: Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.

N12 · Are randomization and assessment roles verified?

Required materials and conditions: Allocation, concealment, multicenter structure, blinding and assessment/analysis roles
Conditions for verification: Material for Allocation, concealment, multicenter structure, blinding and assessment/analysis roles must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.
Requirement and applicability: Required
Application exceptions: Preserve selected subclaim C and its within-group -12.9 mmHg note. Distinguish absent subclaim score/status/axes from parent grade C with 54 points. Within-group changes or a historical simple difference are not adjusted between-group effects; maintenance is not a minimum starting dose. Create no new numbers, CIs, totals, grades, independence/safety certification or exercise, breathing, medication or treatment instructions.
Why this condition is needed: This condition connects Allocation, concealment, multicenter structure, blinding and assessment/analysis roles with selected 12-week resting systolic pressure, within- versus between-group comparisons, initial training versus maintenance, and measurement, denominator, support and harm boundaries.
Referenced methods: Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.

N13 · Are between-group analysis and missing-data handling verified?

Required materials and conditions: Estimand, baseline adjustment, ITT/PP, repeated/missing data and sensitivity analyses
Conditions for verification: Material for Estimand, baseline adjustment, ITT/PP, repeated/missing data and sensitivity analyses must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.
Requirement and applicability: Required
Application exceptions: Preserve selected subclaim C and its within-group -12.9 mmHg note. Distinguish absent subclaim score/status/axes from parent grade C with 54 points. Within-group changes or a historical simple difference are not adjusted between-group effects; maintenance is not a minimum starting dose. Create no new numbers, CIs, totals, grades, independence/safety certification or exercise, breathing, medication or treatment instructions.
Why this condition is needed: This condition connects Estimand, baseline adjustment, ITT/PP, repeated/missing data and sensitivity analyses with selected 12-week resting systolic pressure, within- versus between-group comparisons, initial training versus maintenance, and measurement, denominator, support and harm boundaries.
Referenced methods: Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.

N14 · How do SBP and DBP results differ?

Required materials and conditions: Values, denominators and prospective analysis for each pressure measure
Conditions for verification: Material for Values, denominators and prospective analysis for each pressure measure must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.
Requirement and applicability: Required
Application exceptions: Preserve selected subclaim C and its within-group -12.9 mmHg note. Distinguish absent subclaim score/status/axes from parent grade C with 54 points. Within-group changes or a historical simple difference are not adjusted between-group effects; maintenance is not a minimum starting dose. Create no new numbers, CIs, totals, grades, independence/safety certification or exercise, breathing, medication or treatment instructions.
Why this condition is needed: This condition connects Values, denominators and prospective analysis for each pressure measure with selected 12-week resting systolic pressure, within- versus between-group comparisons, initial training versus maintenance, and measurement, denominator, support and harm boundaries.
Referenced methods: Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.

N15 · What does the separate 4-week sham trial show?

Required materials and conditions: Population, intensity, comparators, duration and each pressure outcome
Conditions for verification: Material for Population, intensity, comparators, duration and each pressure outcome must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.
Requirement and applicability: Required
Application exceptions: Preserve selected subclaim C and its within-group -12.9 mmHg note. Distinguish absent subclaim score/status/axes from parent grade C with 54 points. Within-group changes or a historical simple difference are not adjusted between-group effects; maintenance is not a minimum starting dose. Create no new numbers, CIs, totals, grades, independence/safety certification or exercise, breathing, medication or treatment instructions.
Why this condition is needed: This condition connects Population, intensity, comparators, duration and each pressure outcome with selected 12-week resting systolic pressure, within- versus between-group comparisons, initial training versus maintenance, and measurement, denominator, support and harm boundaries.
Referenced methods: Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.

N16 · Are registration identifiers distinct from prospective materials?

Required materials and conditions: Citation identifier, absent evidence-summary field and prospective plans
Conditions for verification: Material for Citation identifier, absent evidence-summary field and prospective plans must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.
Requirement and applicability: Required
Application exceptions: Preserve selected subclaim C and its within-group -12.9 mmHg note. Distinguish absent subclaim score/status/axes from parent grade C with 54 points. Within-group changes or a historical simple difference are not adjusted between-group effects; maintenance is not a minimum starting dose. Create no new numbers, CIs, totals, grades, independence/safety certification or exercise, breathing, medication or treatment instructions.
Why this condition is needed: This condition connects Citation identifier, absent evidence-summary field and prospective plans with selected 12-week resting systolic pressure, within- versus between-group comparisons, initial training versus maintenance, and measurement, denominator, support and harm boundaries.
Referenced methods: Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.

N17 · Are replication and report/sample relationships verified?

Required materials and conditions: Duration, intervention, comparator, support, shared samples and related reports
Conditions for verification: Material for Duration, intervention, comparator, support, shared samples and related reports must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.
Requirement and applicability: Required
Application exceptions: Preserve selected subclaim C and its within-group -12.9 mmHg note. Distinguish absent subclaim score/status/axes from parent grade C with 54 points. Within-group changes or a historical simple difference are not adjusted between-group effects; maintenance is not a minimum starting dose. Create no new numbers, CIs, totals, grades, independence/safety certification or exercise, breathing, medication or treatment instructions.
Why this condition is needed: This condition connects Duration, intervention, comparator, support, shared samples and related reports with selected 12-week resting systolic pressure, within- versus between-group comparisons, initial training versus maintenance, and measurement, denominator, support and harm boundaries.
Referenced methods: Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.

N18 · Does resting pressure establish medication replacement or event prevention?

Required materials and conditions: Surrogate, medication comparison, treatment replacement and cardiovascular-event boundaries
Conditions for verification: Material for Surrogate, medication comparison, treatment replacement and cardiovascular-event boundaries must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.
Requirement and applicability: Required
Application exceptions: Preserve selected subclaim C and its within-group -12.9 mmHg note. Distinguish absent subclaim score/status/axes from parent grade C with 54 points. Within-group changes or a historical simple difference are not adjusted between-group effects; maintenance is not a minimum starting dose. Create no new numbers, CIs, totals, grades, independence/safety certification or exercise, breathing, medication or treatment instructions.
Why this condition is needed: This condition connects Surrogate, medication comparison, treatment replacement and cardiovascular-event boundaries with selected 12-week resting systolic pressure, within- versus between-group comparisons, initial training versus maintenance, and measurement, denominator, support and harm boundaries.
Referenced methods: Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.

N19 · Are maintenance and long-term persistence verified?

Required materials and conditions: Initial, maintenance and long-term results, populations, denominators and comparisons
Conditions for verification: Material for Initial, maintenance and long-term results, populations, denominators and comparisons must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.
Requirement and applicability: Required
Application exceptions: Preserve selected subclaim C and its within-group -12.9 mmHg note. Distinguish absent subclaim score/status/axes from parent grade C with 54 points. Within-group changes or a historical simple difference are not adjusted between-group effects; maintenance is not a minimum starting dose. Create no new numbers, CIs, totals, grades, independence/safety certification or exercise, breathing, medication or treatment instructions.
Why this condition is needed: This condition connects Initial, maintenance and long-term results, populations, denominators and comparisons with selected 12-week resting systolic pressure, within- versus between-group comparisons, initial training versus maintenance, and measurement, denominator, support and harm boundaries.
Referenced methods: Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.

N20 · Are actual delivery, coactivity and adherence verified?

Required materials and conditions: Concurrent exercise, medication/lifestyle changes, supervision, delivery and data attribution
Conditions for verification: Material for Concurrent exercise, medication/lifestyle changes, supervision, delivery and data attribution must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.
Requirement and applicability: Supplementary
Application exceptions: Preserve selected subclaim C and its within-group -12.9 mmHg note. Distinguish absent subclaim score/status/axes from parent grade C with 54 points. Within-group changes or a historical simple difference are not adjusted between-group effects; maintenance is not a minimum starting dose. Create no new numbers, CIs, totals, grades, independence/safety certification or exercise, breathing, medication or treatment instructions.
Why this condition is needed: This condition connects Concurrent exercise, medication/lifestyle changes, supervision, delivery and data attribution with selected 12-week resting systolic pressure, within- versus between-group comparisons, initial training versus maintenance, and measurement, denominator, support and harm boundaries.
Referenced methods: Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.

N21 · What are Cohen’s public funding and COI declarations?

Required materials and conditions: Funding, product support, employed authors, analysis/publication roles and COI
Conditions for verification: Material for Funding, product support, employed authors, analysis/publication roles and COI must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.
Requirement and applicability: Required
Application exceptions: Preserve selected subclaim C and its within-group -12.9 mmHg note. Distinguish absent subclaim score/status/axes from parent grade C with 54 points. Within-group changes or a historical simple difference are not adjusted between-group effects; maintenance is not a minimum starting dose. Create no new numbers, CIs, totals, grades, independence/safety certification or exercise, breathing, medication or treatment instructions.
Why this condition is needed: This condition connects Funding, product support, employed authors, analysis/publication roles and COI with selected 12-week resting systolic pressure, within- versus between-group comparisons, initial training versus maintenance, and measurement, denominator, support and harm boundaries.
Referenced methods: Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.

N22 · Is Decaux’s funding verified?

Required materials and conditions: Separate funding, support, employed-author and interest materials
Conditions for verification: Material for Separate funding, support, employed-author and interest materials must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.
Requirement and applicability: Required
Application exceptions: Preserve selected subclaim C and its within-group -12.9 mmHg note. Distinguish absent subclaim score/status/axes from parent grade C with 54 points. Within-group changes or a historical simple difference are not adjusted between-group effects; maintenance is not a minimum starting dose. Create no new numbers, CIs, totals, grades, independence/safety certification or exercise, breathing, medication or treatment instructions.
Why this condition is needed: This condition connects Separate funding, support, employed-author and interest materials with selected 12-week resting systolic pressure, within- versus between-group comparisons, initial training versus maintenance, and measurement, denominator, support and harm boundaries.
Referenced methods: Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.

N23 · Do 0 reported adverse events guarantee safety?

Required materials and conditions: Harm definitions, collection, arm exposure/denominators, discontinuation and missingness
Conditions for verification: Material for Harm definitions, collection, arm exposure/denominators, discontinuation and missingness must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.
Requirement and applicability: Supplementary
Application exceptions: Preserve selected subclaim C and its within-group -12.9 mmHg note. Distinguish absent subclaim score/status/axes from parent grade C with 54 points. Within-group changes or a historical simple difference are not adjusted between-group effects; maintenance is not a minimum starting dose. Create no new numbers, CIs, totals, grades, independence/safety certification or exercise, breathing, medication or treatment instructions.
Why this condition is needed: This condition connects Harm definitions, collection, arm exposure/denominators, discontinuation and missingness with selected 12-week resting systolic pressure, within- versus between-group comparisons, initial training versus maintenance, and measurement, denominator, support and harm boundaries.
Referenced methods: Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.

N24 · Are acute and longer-term resting pressure the same?

Required materials and conditions: Acute holds, resting results, bibliography, population and denominators
Conditions for verification: Material for Acute holds, resting results, bibliography, population and denominators must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.
Requirement and applicability: Supplementary
Application exceptions: Preserve selected subclaim C and its within-group -12.9 mmHg note. Distinguish absent subclaim score/status/axes from parent grade C with 54 points. Within-group changes or a historical simple difference are not adjusted between-group effects; maintenance is not a minimum starting dose. Create no new numbers, CIs, totals, grades, independence/safety certification or exercise, breathing, medication or treatment instructions.
Why this condition is needed: This condition connects Acute holds, resting results, bibliography, population and denominators with selected 12-week resting systolic pressure, within- versus between-group comparisons, initial training versus maintenance, and measurement, denominator, support and harm boundaries.
Referenced methods: Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.

N25 · Are long-term and vulnerable-population harms verified?

Required materials and conditions: Supervision, exposure, vulnerable populations, concurrent factors and long-term harms
Conditions for verification: Material for Supervision, exposure, vulnerable populations, concurrent factors and long-term harms must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.
Requirement and applicability: Supplementary
Application exceptions: Preserve selected subclaim C and its within-group -12.9 mmHg note. Distinguish absent subclaim score/status/axes from parent grade C with 54 points. Within-group changes or a historical simple difference are not adjusted between-group effects; maintenance is not a minimum starting dose. Create no new numbers, CIs, totals, grades, independence/safety certification or exercise, breathing, medication or treatment instructions.
Why this condition is needed: This condition connects Supervision, exposure, vulnerable populations, concurrent factors and long-term harms with selected 12-week resting systolic pressure, within- versus between-group comparisons, initial training versus maintenance, and measurement, denominator, support and harm boundaries.
Referenced methods: Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.

N26 · How are original verdicts, dates and corrections preserved?

Required materials and conditions: Parent/subclaim grades, scores, axes, both languages, dates and absent values
Conditions for verification: Material for Parent/subclaim grades, scores, axes, both languages, dates and absent values must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.
Requirement and applicability: Required
Application exceptions: Preserve selected subclaim C and its within-group -12.9 mmHg note. Distinguish absent subclaim score/status/axes from parent grade C with 54 points. Within-group changes or a historical simple difference are not adjusted between-group effects; maintenance is not a minimum starting dose. Create no new numbers, CIs, totals, grades, independence/safety certification or exercise, breathing, medication or treatment instructions.
Why this condition is needed: This condition connects Parent/subclaim grades, scores, axes, both languages, dates and absent values with selected 12-week resting systolic pressure, within- versus between-group comparisons, initial training versus maintenance, and measurement, denominator, support and harm boundaries.
Referenced methods: Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.

N27 · What material was actually read?

Required materials and conditions: Report/material links and paper, registration, plan and support states
Conditions for verification: Material for Report/material links and paper, registration, plan and support states must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.
Requirement and applicability: Required
Application exceptions: Preserve selected subclaim C and its within-group -12.9 mmHg note. Distinguish absent subclaim score/status/axes from parent grade C with 54 points. Within-group changes or a historical simple difference are not adjusted between-group effects; maintenance is not a minimum starting dose. Create no new numbers, CIs, totals, grades, independence/safety certification or exercise, breathing, medication or treatment instructions.
Why this condition is needed: This condition connects Report/material links and paper, registration, plan and support states with selected 12-week resting systolic pressure, within- versus between-group comparisons, initial training versus maintenance, and measurement, denominator, support and harm boundaries.
Referenced methods: Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.

Referenced methods and the sections actually reviewed

M03 · Cochrane Handbook 6.5 (2024), chapter updated 2023-08

Official methodology · §3.1, §3.2.1–3.2.3, MECIR C5/C7/C13

Referenced principle: Clearly record the question, eligibility conditions and reasons for changes, and distinguish variations in interventions.
Extent of review: Existing methodological links were reused for production. External originals were not reread and methodological content was not reassessed.

M04 · Cochrane Handbook 6.5.1 (2025), chapter updated 2025-03

Official methodology · §4.5, §4.6.1–4.6.3, MECIR C42

Referenced principle: Distinguish studies from reports and link them; do not omit a study solely because results are unreported.
Extent of review: Existing methodological links were reused for production. External originals were not reread and methodological content was not reassessed.

M08 · Cochrane Handbook 6.5 (2024), chapter updated 2019-10

Official methodology · §8.1–8.2.3, Table 8.2.a

Referenced principle: Define the outcome and effect of interest, then examine randomization, deviations, missing data, measurement and selective reporting.
Extent of review: Existing methodological links were reused for production. External originals were not reread and methodological content was not reassessed.

M15 · Cochrane Handbook 6.5 (2024), chapter updated 2023-08

Official methodology · §15.2.4, §15.3.1–15.3.3

Referenced principle: Distinguish effect estimates, intervals, importance and applicability. Sample size alone does not determine precision.
Extent of review: Existing methodological links were reused for production. External originals were not reread and methodological content was not reassessed.

M19 · Cochrane Handbook 6.5 (2024), chapter updated 2019-10

Official methodology · §19.1.2, §19.2.1–19.2.4

Referenced principle: Harm questions may require different designs, populations and follow-up from efficacy questions. Case reports do not establish incidence rates.
Extent of review: Existing methodological links were reused for production. External originals were not reread and methodological content was not reassessed.

What the statuses mean

Met: A state used when required evidence is confirmed after user review. This production does not declare that review complete.
Partly verified: Some information in the stored summary is linked into the table. External comparison/content review is not complete.
Unverified: The article leaves this unverified, or required material is absent from the current stored summary. This is distinct from zero, absence or safety.
Review incomplete: User review pending.
Not reported: Not reported within the stored material actually read; not extended to the entire primary paper.
Inaccessible: Means an actual access failure. Access not attempted here is not assigned this state.
Not applicable: Not used as a substitute for an evidence gap.
Conflicting data: Requires an observed disagreement under the same comparison criteria; not automatically judged in this production.
Insufficient evidence for the conditions: Marks a gap in additional material required by the selected conditions; not a new efficacy grade.

Change history

2026-10-16 · Public page/material version 1.0

Public pages and materials were prepared from the existing 27 items. No new clinical search, verification-status change or scoring was performed.

The stored-material review date (Not recorded) and original evidence cut-off (2026-09-07) were retained unchanged.

Researcher downloads

These materials provide the same evidence, scope and verification status as this page.

View all item details

N01 · What is the selected 12-week resting-SBP question?

Current findings: The selection is lower resting SBP after 12 weeks of supervised wall sits. Preserve subclaim C and the within-group -12.9 mmHg note. Parent grade C with 54 points is separate context.
Verification status: Partly verified
Materials actually read: Stored summary read; external abstracts, full texts, registration, protocols, SAPs and support disclosures unread
Why unverified: The selected claim, parent material and reports are distinguished and transferred from the stored summary. Detailed original material is unverified and review of existing content remains incomplete. This does not establish completed clinical review or certification.
Reason for missing information: The subclaim has no score, status or axis fields. Do not fill them with parent values.
Required materials and conditions: Exact subclaim, grade/note and parent verdict
Materials to obtain first: The subclaim has no score, status or axis fields. Do not fill them with parent values.
Further research: Material needed: The subclaim has no score, status or axis fields. Do not fill them with parent values. This records needed materials; no new research was executed.
Remaining uncertainty: External original material is unread and review of existing content remains incomplete. Original grades, scores, axes, historical verification and independence statements are not treated as new verdicts or certification.
Conditions for verification: Material for Exact subclaim, grade/note and parent verdict must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.
Why this condition is needed: This condition connects Exact subclaim, grade/note and parent verdict with selected 12-week resting systolic pressure, within- versus between-group comparisons, initial training versus maintenance, and measurement, denominator, support and harm boundaries.
Application exceptions: Preserve selected subclaim C and its within-group -12.9 mmHg note. Distinguish absent subclaim score/status/axes from parent grade C with 54 points. Within-group changes or a historical simple difference are not adjusted between-group effects; maintenance is not a minimum starting dose. Create no new numbers, CIs, totals, grades, independence/safety certification or exercise, breathing, medication or treatment instructions.
Referenced methods: Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.

Related sources S01

N02 · Which adults with hypertension participated?

Current findings: Cohen records 77 untreated adults aged 35–65 with hypertension.
Verification status: Partly verified
Materials actually read: Stored summary read; external abstracts, full texts, registration, protocols, SAPs and support disclosures unread
Why unverified: The selected claim, parent material and reports are distinguished and transferred from the stored summary. Detailed original material is unverified and review of existing content remains incomplete. This does not establish completed clinical review or certification.
Reason for missing information: Exact diagnosis, baseline severity, eligibility/exclusions, sex, comorbidities and recruitment details are needed. Do not extend to treated people or other ages.
Required materials and conditions: Diagnosis, age, medication status, baseline risk and eligibility
Materials to obtain first: Exact diagnosis, baseline severity, eligibility/exclusions, sex, comorbidities and recruitment details are needed. Do not extend to treated people or other ages.
Further research: Material needed: Exact diagnosis, baseline severity, eligibility/exclusions, sex, comorbidities and recruitment details are needed. Do not extend to treated people or other ages. This records needed materials; no new research was executed.
Remaining uncertainty: External original material is unread and review of existing content remains incomplete. Original grades, scores, axes, historical verification and independence statements are not treated as new verdicts or certification.
Conditions for verification: Material for Diagnosis, age, medication status, baseline risk and eligibility must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.
Why this condition is needed: This condition connects Diagnosis, age, medication status, baseline risk and eligibility with selected 12-week resting systolic pressure, within- versus between-group comparisons, initial training versus maintenance, and measurement, denominator, support and harm boundaries.
Application exceptions: Preserve selected subclaim C and its within-group -12.9 mmHg note. Distinguish absent subclaim score/status/axes from parent grade C with 54 points. Within-group changes or a historical simple difference are not adjusted between-group effects; maintenance is not a minimum starting dose. Create no new numbers, CIs, totals, grades, independence/safety certification or exercise, breathing, medication or treatment instructions.
Referenced methods: Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.

Related sources S01

N03 · What was the supervised wall-sit intervention?

Current findings: The original text records angle, intensity and supervision as parts of supervised isometric wall sits.
Verification status: Partly verified
Materials actually read: Stored summary read; external abstracts, full texts, registration, protocols, SAPs and support disclosures unread
Why unverified: The selected claim, parent material and reports are distinguished and transferred from the stored summary. Detailed original material is unverified and review of existing content remains incomplete. This does not establish completed clinical review or certification.
Reason for missing information: Individual settings, supervision, actual delivery and adherence are needed. Research conditions are not new exercise instructions.
Required materials and conditions: Supervision, knee angle, intensity calibration, actual delivery and components
Materials to obtain first: Individual settings, supervision, actual delivery and adherence are needed. Research conditions are not new exercise instructions.
Further research: Material needed: Individual settings, supervision, actual delivery and adherence are needed. Research conditions are not new exercise instructions. This records needed materials; no new research was executed.
Remaining uncertainty: External original material is unread and review of existing content remains incomplete. Original grades, scores, axes, historical verification and independence statements are not treated as new verdicts or certification.
Conditions for verification: Material for Supervision, knee angle, intensity calibration, actual delivery and components must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.
Why this condition is needed: This condition connects Supervision, knee angle, intensity calibration, actual delivery and components with selected 12-week resting systolic pressure, within- versus between-group comparisons, initial training versus maintenance, and measurement, denominator, support and harm boundaries.
Application exceptions: Preserve selected subclaim C and its within-group -12.9 mmHg note. Distinguish absent subclaim score/status/axes from parent grade C with 54 points. Within-group changes or a historical simple difference are not adjusted between-group effects; maintenance is not a minimum starting dose. Create no new numbers, CIs, totals, grades, independence/safety certification or exercise, breathing, medication or treatment instructions.
Referenced methods: Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.

Related sources S01

N04 · How do initial training and maintenance differ?

Current findings: Distinguish original initial training 3 times weekly for 12 weeks, 4 holds of 2 minutes with 2-minute seated rests, and later maintenance 1 time weekly.
Verification status: Partly verified
Materials actually read: Stored summary read; external abstracts, full texts, registration, protocols, SAPs and support disclosures unread
Why unverified: The selected claim, parent material and reports are distinguished and transferred from the stored summary. Detailed original material is unverified and review of existing content remains incomplete. This does not establish completed clinical review or certification.
Reason for missing information: Maintenance allocation, duration, denominators and detailed results are needed. Do not transfer maintenance into a minimum starting dose.
Required materials and conditions: Separate attribution of initial/maintenance schedules and analyses
Materials to obtain first: Maintenance allocation, duration, denominators and detailed results are needed. Do not transfer maintenance into a minimum starting dose.
Further research: Material needed: Maintenance allocation, duration, denominators and detailed results are needed. Do not transfer maintenance into a minimum starting dose. This records needed materials; no new research was executed.
Remaining uncertainty: External original material is unread and review of existing content remains incomplete. Original grades, scores, axes, historical verification and independence statements are not treated as new verdicts or certification.
Conditions for verification: Material for Separate attribution of initial/maintenance schedules and analyses must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.
Why this condition is needed: This condition connects Separate attribution of initial/maintenance schedules and analyses with selected 12-week resting systolic pressure, within- versus between-group comparisons, initial training versus maintenance, and measurement, denominator, support and harm boundaries.
Application exceptions: Preserve selected subclaim C and its within-group -12.9 mmHg note. Distinguish absent subclaim score/status/axes from parent grade C with 54 points. Within-group changes or a historical simple difference are not adjusted between-group effects; maintenance is not a minimum starting dose. Create no new numbers, CIs, totals, grades, independence/safety certification or exercise, breathing, medication or treatment instructions.
Referenced methods: Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.

Related sources S01

N05 · What were the actual comparators?

Current findings: 77 participants were assigned to 3 handgrip, wall-sit and no-exercise arms. Selected values describe wall sit versus no exercise.
Verification status: Partly verified
Materials actually read: Stored summary read; external abstracts, full texts, registration, protocols, SAPs and support disclosures unread
Why unverified: The selected claim, parent material and reports are distinguished and transferred from the stored summary. Detailed original material is unverified and review of existing content remains incomplete. This does not establish completed clinical review or certification.
Reason for missing information: Arm allocation, denominators, contact, expectations and usual activity are needed. Do not combine handgrip with the wall-sit intervention.
Required materials and conditions: Wall sit versus no exercise and the scope of the other exercise arm
Materials to obtain first: Arm allocation, denominators, contact, expectations and usual activity are needed. Do not combine handgrip with the wall-sit intervention.
Further research: Material needed: Arm allocation, denominators, contact, expectations and usual activity are needed. Do not combine handgrip with the wall-sit intervention. This records needed materials; no new research was executed.
Remaining uncertainty: External original material is unread and review of existing content remains incomplete. Original grades, scores, axes, historical verification and independence statements are not treated as new verdicts or certification.
Conditions for verification: Material for Wall sit versus no exercise and the scope of the other exercise arm must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.
Why this condition is needed: This condition connects Wall sit versus no exercise and the scope of the other exercise arm with selected 12-week resting systolic pressure, within- versus between-group comparisons, initial training versus maintenance, and measurement, denominator, support and harm boundaries.
Application exceptions: Preserve selected subclaim C and its within-group -12.9 mmHg note. Distinguish absent subclaim score/status/axes from parent grade C with 54 points. Within-group changes or a historical simple difference are not adjusted between-group effects; maintenance is not a minimum starting dose. Create no new numbers, CIs, totals, grades, independence/safety certification or exercise, breathing, medication or treatment instructions.
Referenced methods: Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.

Related sources S01

N06 · Does complete follow-up establish endpoint denominators?

Current findings: Preserve the original record that all 77 Cohen participants completed.
Verification status: Partly verified
Materials actually read: Stored summary read; external abstracts, full texts, registration, protocols, SAPs and support disclosures unread
Why unverified: The selected claim, parent material and reports are distinguished and transferred from the stored summary. Detailed original material is unverified and review of existing content remains incomplete. This does not establish completed clinical review or certification.
Reason for missing information: Wall-sit, no-exercise and handgrip denominators, valid/missing measurements and analysis rules are needed. Completion does not establish complete measurement of every outcome.
Required materials and conditions: Overall allocation/completion versus arm denominators, missing measurements and analysis rules
Materials to obtain first: Wall-sit, no-exercise and handgrip denominators, valid/missing measurements and analysis rules are needed. Completion does not establish complete measurement of every outcome.
Further research: Material needed: Wall-sit, no-exercise and handgrip denominators, valid/missing measurements and analysis rules are needed. Completion does not establish complete measurement of every outcome. This records needed materials; no new research was executed.
Remaining uncertainty: External original material is unread and review of existing content remains incomplete. Original grades, scores, axes, historical verification and independence statements are not treated as new verdicts or certification.
Conditions for verification: Material for Overall allocation/completion versus arm denominators, missing measurements and analysis rules must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.
Why this condition is needed: This condition connects Overall allocation/completion versus arm denominators, missing measurements and analysis rules with selected 12-week resting systolic pressure, within- versus between-group comparisons, initial training versus maintenance, and measurement, denominator, support and harm boundaries.
Application exceptions: Preserve selected subclaim C and its within-group -12.9 mmHg note. Distinguish absent subclaim score/status/axes from parent grade C with 54 points. Within-group changes or a historical simple difference are not adjusted between-group effects; maintenance is not a minimum starting dose. Create no new numbers, CIs, totals, grades, independence/safety certification or exercise, breathing, medication or treatment instructions.
Referenced methods: Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.

Related sources S01

N07 · How was resting office SBP measured?

Current findings: The endpoint is recorded as 12-week office resting blood pressure.
Verification status: Partly verified
Materials actually read: Stored summary read; external abstracts, full texts, registration, protocols, SAPs and support disclosures unread
Why unverified: The selected claim, parent material and reports are distinguished and transferred from the stored summary. Detailed original material is unverified and review of existing content remains incomplete. This does not establish completed clinical review or certification.
Reason for missing information: Equipment, rest, repetitions, assessor blinding, standardization and medication/activity/time conditions are needed. Do not combine with in-exercise pressure.
Required materials and conditions: Resting conditions, equipment, repetitions, assessor and timing
Materials to obtain first: Equipment, rest, repetitions, assessor blinding, standardization and medication/activity/time conditions are needed. Do not combine with in-exercise pressure.
Further research: Material needed: Equipment, rest, repetitions, assessor blinding, standardization and medication/activity/time conditions are needed. Do not combine with in-exercise pressure. This records needed materials; no new research was executed.
Remaining uncertainty: External original material is unread and review of existing content remains incomplete. Original grades, scores, axes, historical verification and independence statements are not treated as new verdicts or certification.
Conditions for verification: Material for Resting conditions, equipment, repetitions, assessor and timing must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.
Why this condition is needed: This condition connects Resting conditions, equipment, repetitions, assessor and timing with selected 12-week resting systolic pressure, within- versus between-group comparisons, initial training versus maintenance, and measurement, denominator, support and harm boundaries.
Application exceptions: Preserve selected subclaim C and its within-group -12.9 mmHg note. Distinguish absent subclaim score/status/axes from parent grade C with 54 points. Within-group changes or a historical simple difference are not adjusted between-group effects; maintenance is not a minimum starting dose. Create no new numbers, CIs, totals, grades, independence/safety certification or exercise, breathing, medication or treatment instructions.
Referenced methods: Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.

Related sources S01

N08 · Which arms do baseline and final values describe?

Current findings: Preserve wall sit 141.2→128.3 and no exercise 138.9→138.5 mmHg.
Verification status: Partly verified
Materials actually read: Stored summary read; external abstracts, full texts, registration, protocols, SAPs and support disclosures unread
Why unverified: The selected claim, parent material and reports are distinguished and transferred from the stored summary. Detailed original material is unverified and review of existing content remains incomplete. This does not establish completed clinical review or certification.
Reason for missing information: Arm denominators, variance, distributions, models and CIs are needed. Calculate no new difference, change or effect.
Required materials and conditions: Original wall-sit/no-exercise values, units and baseline/final correspondence
Materials to obtain first: Arm denominators, variance, distributions, models and CIs are needed. Calculate no new difference, change or effect.
Further research: Material needed: Arm denominators, variance, distributions, models and CIs are needed. Calculate no new difference, change or effect. This records needed materials; no new research was executed.
Remaining uncertainty: External original material is unread and review of existing content remains incomplete. Original grades, scores, axes, historical verification and independence statements are not treated as new verdicts or certification.
Conditions for verification: Material for Original wall-sit/no-exercise values, units and baseline/final correspondence must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.
Why this condition is needed: This condition connects Original wall-sit/no-exercise values, units and baseline/final correspondence with selected 12-week resting systolic pressure, within- versus between-group comparisons, initial training versus maintenance, and measurement, denominator, support and harm boundaries.
Application exceptions: Preserve selected subclaim C and its within-group -12.9 mmHg note. Distinguish absent subclaim score/status/axes from parent grade C with 54 points. Within-group changes or a historical simple difference are not adjusted between-group effects; maintenance is not a minimum starting dose. Create no new numbers, CIs, totals, grades, independence/safety certification or exercise, breathing, medication or treatment instructions.
Referenced methods: Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.

Related sources S01

N09 · What do within-group changes and P values mean?

Current findings: Parent records give within-wall-sit -12.9 mmHg/P<.001 and no-exercise -0.4 mmHg. The selected note also describes a within-group -12.9 change.
Verification status: Partly verified
Materials actually read: Stored summary read; external abstracts, full texts, registration, protocols, SAPs and support disclosures unread
Why unverified: The selected claim, parent material and reports are distinguished and transferred from the stored summary. Detailed original material is unverified and review of existing content remains incomplete. This does not establish completed clinical review or certification.
Reason for missing information: A within-group P value is not a between-group P value. Within-group CIs, variance, denominators and between-group tests are needed.
Required materials and conditions: Within-group changes, tests, denominators and scope of estimation
Materials to obtain first: A within-group P value is not a between-group P value. Within-group CIs, variance, denominators and between-group tests are needed.
Further research: Material needed: A within-group P value is not a between-group P value. Within-group CIs, variance, denominators and between-group tests are needed. This records needed materials; no new research was executed.
Remaining uncertainty: External original material is unread and review of existing content remains incomplete. Original grades, scores, axes, historical verification and independence statements are not treated as new verdicts or certification.
Conditions for verification: Material for Within-group changes, tests, denominators and scope of estimation must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.
Why this condition is needed: This condition connects Within-group changes, tests, denominators and scope of estimation with selected 12-week resting systolic pressure, within- versus between-group comparisons, initial training versus maintenance, and measurement, denominator, support and harm boundaries.
Application exceptions: Preserve selected subclaim C and its within-group -12.9 mmHg note. Distinguish absent subclaim score/status/axes from parent grade C with 54 points. Within-group changes or a historical simple difference are not adjusted between-group effects; maintenance is not a minimum starting dose. Create no new numbers, CIs, totals, grades, independence/safety certification or exercise, breathing, medication or treatment instructions.
Referenced methods: Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.

Related sources S01

N10 · Is the historical simple difference an adjusted effect?

Current findings: Parent -12.5 mmHg is recorded as a simple difference between changes, not an adjusted estimate. It was not calculated in this conversion.
Verification status: Partly verified
Materials actually read: Stored summary read; external abstracts, full texts, registration, protocols, SAPs and support disclosures unread
Why unverified: The selected claim, parent material and reports are distinguished and transferred from the stored summary. Detailed original material is unverified and review of existing content remains incomplete. This does not establish completed clinical review or certification.
Reason for missing information: Adjusted effects, models, exact between-group 95% CIs and P values are needed. Do not promote a historical value into a new estimate.
Required materials and conditions: Original arithmetic wording versus adjusted between-group estimation
Materials to obtain first: Adjusted effects, models, exact between-group 95% CIs and P values are needed. Do not promote a historical value into a new estimate.
Further research: Material needed: Adjusted effects, models, exact between-group 95% CIs and P values are needed. Do not promote a historical value into a new estimate. This records needed materials; no new research was executed.
Remaining uncertainty: External original material is unread and review of existing content remains incomplete. Original grades, scores, axes, historical verification and independence statements are not treated as new verdicts or certification.
Conditions for verification: Material for Original arithmetic wording versus adjusted between-group estimation must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.
Why this condition is needed: This condition connects Original arithmetic wording versus adjusted between-group estimation with selected 12-week resting systolic pressure, within- versus between-group comparisons, initial training versus maintenance, and measurement, denominator, support and harm boundaries.
Application exceptions: Preserve selected subclaim C and its within-group -12.9 mmHg note. Distinguish absent subclaim score/status/axes from parent grade C with 54 points. Within-group changes or a historical simple difference are not adjusted between-group effects; maintenance is not a minimum starting dose. Create no new numbers, CIs, totals, grades, independence/safety certification or exercise, breathing, medication or treatment instructions.
Referenced methods: Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.

Related sources S01

N11 · Are endpoint hierarchy and registration verified?

Current findings: The original leaves the exact prospective endpoint hierarchy unverified. Cohen’s evidence summary has no registration-identifier field.
Verification status: Unverified
Materials actually read: Stored summary read; external abstracts, full texts, registration, protocols, SAPs and support disclosures unread
Why unverified: The selected claim, parent material and reports are distinguished and transferred from the stored summary. Detailed original material is unverified and review of existing content remains incomplete. This does not establish completed clinical review or certification.
Reason for missing information: Registration, protocols, SAPs, multiplicity and change history are unread. Do not fill an absent field as unregistered or not applicable.
Required materials and conditions: SBP/DBP, initial/maintenance, prospective 1st/2nd outcomes and changes
Materials to obtain first: Registration, protocols, SAPs, multiplicity and change history are unread. Do not fill an absent field as unregistered or not applicable.
Further research: Material needed: Registration, protocols, SAPs, multiplicity and change history are unread. Do not fill an absent field as unregistered or not applicable. This records needed materials; no new research was executed.
Remaining uncertainty: External original material is unread and review of existing content remains incomplete. Original grades, scores, axes, historical verification and independence statements are not treated as new verdicts or certification.
Conditions for verification: Material for SBP/DBP, initial/maintenance, prospective 1st/2nd outcomes and changes must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.
Why this condition is needed: This condition connects SBP/DBP, initial/maintenance, prospective 1st/2nd outcomes and changes with selected 12-week resting systolic pressure, within- versus between-group comparisons, initial training versus maintenance, and measurement, denominator, support and harm boundaries.
Application exceptions: Preserve selected subclaim C and its within-group -12.9 mmHg note. Distinguish absent subclaim score/status/axes from parent grade C with 54 points. Within-group changes or a historical simple difference are not adjusted between-group effects; maintenance is not a minimum starting dose. Create no new numbers, CIs, totals, grades, independence/safety certification or exercise, breathing, medication or treatment instructions.
Referenced methods: Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.

Related sources S01

N12 · Are randomization and assessment roles verified?

Current findings: Cohen is recorded as a multicenter 3-arm randomized trial.
Verification status: Partly verified
Materials actually read: Stored summary read; external abstracts, full texts, registration, protocols, SAPs and support disclosures unread
Why unverified: The selected claim, parent material and reports are distinguished and transferred from the stored summary. Detailed original material is unverified and review of existing content remains incomplete. This does not establish completed clinical review or certification.
Reason for missing information: Allocation concealment, center structure, participant/assessor/analyst blinding and expectations are needed.
Required materials and conditions: Allocation, concealment, multicenter structure, blinding and assessment/analysis roles
Materials to obtain first: Allocation concealment, center structure, participant/assessor/analyst blinding and expectations are needed.
Further research: Material needed: Allocation concealment, center structure, participant/assessor/analyst blinding and expectations are needed. This records needed materials; no new research was executed.
Remaining uncertainty: External original material is unread and review of existing content remains incomplete. Original grades, scores, axes, historical verification and independence statements are not treated as new verdicts or certification.
Conditions for verification: Material for Allocation, concealment, multicenter structure, blinding and assessment/analysis roles must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.
Why this condition is needed: This condition connects Allocation, concealment, multicenter structure, blinding and assessment/analysis roles with selected 12-week resting systolic pressure, within- versus between-group comparisons, initial training versus maintenance, and measurement, denominator, support and harm boundaries.
Application exceptions: Preserve selected subclaim C and its within-group -12.9 mmHg note. Distinguish absent subclaim score/status/axes from parent grade C with 54 points. Within-group changes or a historical simple difference are not adjusted between-group effects; maintenance is not a minimum starting dose. Create no new numbers, CIs, totals, grades, independence/safety certification or exercise, breathing, medication or treatment instructions.
Referenced methods: Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.

Related sources S01

N13 · Are between-group analysis and missing-data handling verified?

Current findings: Preserve both complete follow-up and gaps in adjusted effects/CIs.
Verification status: Unverified
Materials actually read: Stored summary read; external abstracts, full texts, registration, protocols, SAPs and support disclosures unread
Why unverified: The selected claim, parent material and reports are distinguished and transferred from the stored summary. Detailed original material is unverified and review of existing content remains incomplete. This does not establish completed clinical review or certification.
Reason for missing information: ITT/PP, valid/excluded measurements, center/repeated-measure models, covariates, missing data and sensitivity analyses are needed.
Required materials and conditions: Estimand, baseline adjustment, ITT/PP, repeated/missing data and sensitivity analyses
Materials to obtain first: ITT/PP, valid/excluded measurements, center/repeated-measure models, covariates, missing data and sensitivity analyses are needed.
Further research: Material needed: ITT/PP, valid/excluded measurements, center/repeated-measure models, covariates, missing data and sensitivity analyses are needed. This records needed materials; no new research was executed.
Remaining uncertainty: External original material is unread and review of existing content remains incomplete. Original grades, scores, axes, historical verification and independence statements are not treated as new verdicts or certification.
Conditions for verification: Material for Estimand, baseline adjustment, ITT/PP, repeated/missing data and sensitivity analyses must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.
Why this condition is needed: This condition connects Estimand, baseline adjustment, ITT/PP, repeated/missing data and sensitivity analyses with selected 12-week resting systolic pressure, within- versus between-group comparisons, initial training versus maintenance, and measurement, denominator, support and harm boundaries.
Application exceptions: Preserve selected subclaim C and its within-group -12.9 mmHg note. Distinguish absent subclaim score/status/axes from parent grade C with 54 points. Within-group changes or a historical simple difference are not adjusted between-group effects; maintenance is not a minimum starting dose. Create no new numbers, CIs, totals, grades, independence/safety certification or exercise, breathing, medication or treatment instructions.
Referenced methods: Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.

Related sources S01

N14 · How do SBP and DBP results differ?

Current findings: Distinguish the key trial’s null between-group DBP result from its SBP signal. Diastolic pressure is a separate subclaim.
Verification status: Partly verified
Materials actually read: Stored summary read; external abstracts, full texts, registration, protocols, SAPs and support disclosures unread
Why unverified: The selected claim, parent material and reports are distinguished and transferred from the stored summary. Detailed original material is unverified and review of existing content remains incomplete. This does not establish completed clinical review or certification.
Reason for missing information: SBP does not substitute for DBP effects. Exact original DBP values, CIs and analyses are needed.
Required materials and conditions: Values, denominators and prospective analysis for each pressure measure
Materials to obtain first: SBP does not substitute for DBP effects. Exact original DBP values, CIs and analyses are needed.
Further research: Material needed: SBP does not substitute for DBP effects. Exact original DBP values, CIs and analyses are needed. This records needed materials; no new research was executed.
Remaining uncertainty: External original material is unread and review of existing content remains incomplete. Original grades, scores, axes, historical verification and independence statements are not treated as new verdicts or certification.
Conditions for verification: Material for Values, denominators and prospective analysis for each pressure measure must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.
Why this condition is needed: This condition connects Values, denominators and prospective analysis for each pressure measure with selected 12-week resting systolic pressure, within- versus between-group comparisons, initial training versus maintenance, and measurement, denominator, support and harm boundaries.
Application exceptions: Preserve selected subclaim C and its within-group -12.9 mmHg note. Distinguish absent subclaim score/status/axes from parent grade C with 54 points. Within-group changes or a historical simple difference are not adjusted between-group effects; maintenance is not a minimum starting dose. Create no new numbers, CIs, totals, grades, independence/safety certification or exercise, breathing, medication or treatment instructions.
Referenced methods: Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.

Related sources S01

N15 · What does the separate 4-week sham trial show?

Current findings: Decaux has 30 participants over 4 weeks with wall sit, low-intensity sham and no exercise. Preserve SBP -15.2±9.2, DBP -4.6±5.0 mmHg and P<.05 versus controls.
Verification status: Partly verified
Materials actually read: Stored summary read; external abstracts, full texts, registration, protocols, SAPs and support disclosures unread
Why unverified: The selected claim, parent material and reports are distinguished and transferred from the stored summary. Detailed original material is unverified and review of existing content remains incomplete. This does not establish completed clinical review or certification.
Reason for missing information: The variance type for ±, arm denominators, original changes/models, comparator-specific contrasts and CIs are needed. Do not turn this into the same 12-week effect or independent confirmation.
Required materials and conditions: Population, intensity, comparators, duration and each pressure outcome
Materials to obtain first: The variance type for ±, arm denominators, original changes/models, comparator-specific contrasts and CIs are needed. Do not turn this into the same 12-week effect or independent confirmation.
Further research: Material needed: The variance type for ±, arm denominators, original changes/models, comparator-specific contrasts and CIs are needed. Do not turn this into the same 12-week effect or independent confirmation. This records needed materials; no new research was executed.
Remaining uncertainty: External original material is unread and review of existing content remains incomplete. Original grades, scores, axes, historical verification and independence statements are not treated as new verdicts or certification.
Conditions for verification: Material for Population, intensity, comparators, duration and each pressure outcome must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.
Why this condition is needed: This condition connects Population, intensity, comparators, duration and each pressure outcome with selected 12-week resting systolic pressure, within- versus between-group comparisons, initial training versus maintenance, and measurement, denominator, support and harm boundaries.
Application exceptions: Preserve selected subclaim C and its within-group -12.9 mmHg note. Distinguish absent subclaim score/status/axes from parent grade C with 54 points. Within-group changes or a historical simple difference are not adjusted between-group effects; maintenance is not a minimum starting dose. Create no new numbers, CIs, totals, grades, independence/safety certification or exercise, breathing, medication or treatment instructions.
Referenced methods: Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.

Related sources S02

N16 · Are registration identifiers distinct from prospective materials?

Current findings: NCT05025202 appears in Decaux’s citation. Neither evidence summary has a registration-identifier field.
Verification status: Partly verified
Materials actually read: Stored summary read; external abstracts, full texts, registration, protocols, SAPs and support disclosures unread
Why unverified: The selected claim, parent material and reports are distinguished and transferred from the stored summary. Detailed original material is unverified and review of existing content remains incomplete. This does not establish completed clinical review or certification.
Reason for missing information: Registration timing, changes, prospective endpoints, protocols and SAPs are unread. An identifier alone does not certify prospective status or independence.
Required materials and conditions: Citation identifier, absent evidence-summary field and prospective plans
Materials to obtain first: Registration timing, changes, prospective endpoints, protocols and SAPs are unread. An identifier alone does not certify prospective status or independence.
Further research: Material needed: Registration timing, changes, prospective endpoints, protocols and SAPs are unread. An identifier alone does not certify prospective status or independence. This records needed materials; no new research was executed.
Remaining uncertainty: External original material is unread and review of existing content remains incomplete. Original grades, scores, axes, historical verification and independence statements are not treated as new verdicts or certification.
Conditions for verification: Material for Citation identifier, absent evidence-summary field and prospective plans must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.
Why this condition is needed: This condition connects Citation identifier, absent evidence-summary field and prospective plans with selected 12-week resting systolic pressure, within- versus between-group comparisons, initial training versus maintenance, and measurement, denominator, support and harm boundaries.
Application exceptions: Preserve selected subclaim C and its within-group -12.9 mmHg note. Distinguish absent subclaim score/status/axes from parent grade C with 54 points. Within-group changes or a historical simple difference are not adjusted between-group effects; maintenance is not a minimum starting dose. Create no new numbers, CIs, totals, grades, independence/safety certification or exercise, breathing, medication or treatment instructions.
Referenced methods: Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.

Related sources S02

N17 · Are replication and report/sample relationships verified?

Current findings: Preserve original supportive directions across small trials and no strict upgrade to R2.
Verification status: Unverified
Materials actually read: Stored summary read; external abstracts, full texts, registration, protocols, SAPs and support disclosures unread
Why unverified: The selected claim, parent material and reports are distinguished and transferred from the stored summary. Detailed original material is unverified and review of existing content remains incomplete. This does not establish completed clinical review or certification.
Reason for missing information: Independent confirmation under the same conditions and unique-trial/participant or replication totals remain unverified. Reports, times, arms and sheets are not new clinical totals.
Required materials and conditions: Duration, intervention, comparator, support, shared samples and related reports
Materials to obtain first: Independent confirmation under the same conditions and unique-trial/participant or replication totals remain unverified. Reports, times, arms and sheets are not new clinical totals.
Further research: Material needed: Independent confirmation under the same conditions and unique-trial/participant or replication totals remain unverified. Reports, times, arms and sheets are not new clinical totals. This records needed materials; no new research was executed.
Remaining uncertainty: External original material is unread and review of existing content remains incomplete. Original grades, scores, axes, historical verification and independence statements are not treated as new verdicts or certification.
Conditions for verification: Material for Duration, intervention, comparator, support, shared samples and related reports must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.
Why this condition is needed: This condition connects Duration, intervention, comparator, support, shared samples and related reports with selected 12-week resting systolic pressure, within- versus between-group comparisons, initial training versus maintenance, and measurement, denominator, support and harm boundaries.
Application exceptions: Preserve selected subclaim C and its within-group -12.9 mmHg note. Distinguish absent subclaim score/status/axes from parent grade C with 54 points. Within-group changes or a historical simple difference are not adjusted between-group effects; maintenance is not a minimum starting dose. Create no new numbers, CIs, totals, grades, independence/safety certification or exercise, breathing, medication or treatment instructions.
Referenced methods: Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.

Related sources S01 S02

N18 · Does resting pressure establish medication replacement or event prevention?

Current findings: The original records that medication replacement and cardiovascular events were not tested. The original grade ? subclaim is separate.
Verification status: Unverified
Materials actually read: Stored summary read; external abstracts, full texts, registration, protocols, SAPs and support disclosures unread
Why unverified: The selected claim, parent material and reports are distinguished and transferred from the stored summary. Detailed original material is unverified and review of existing content remains incomplete. This does not establish completed clinical review or certification.
Reason for missing information: Do not transfer SBP into medication equivalence, dose reduction/replacement, heart-attack prevention or long-term clinical effects. Create no treatment instructions.
Required materials and conditions: Surrogate, medication comparison, treatment replacement and cardiovascular-event boundaries
Materials to obtain first: Do not transfer SBP into medication equivalence, dose reduction/replacement, heart-attack prevention or long-term clinical effects. Create no treatment instructions.
Further research: Material needed: Do not transfer SBP into medication equivalence, dose reduction/replacement, heart-attack prevention or long-term clinical effects. Create no treatment instructions. This records needed materials; no new research was executed.
Remaining uncertainty: External original material is unread and review of existing content remains incomplete. Original grades, scores, axes, historical verification and independence statements are not treated as new verdicts or certification.
Conditions for verification: Material for Surrogate, medication comparison, treatment replacement and cardiovascular-event boundaries must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.
Why this condition is needed: This condition connects Surrogate, medication comparison, treatment replacement and cardiovascular-event boundaries with selected 12-week resting systolic pressure, within- versus between-group comparisons, initial training versus maintenance, and measurement, denominator, support and harm boundaries.
Application exceptions: Preserve selected subclaim C and its within-group -12.9 mmHg note. Distinguish absent subclaim score/status/axes from parent grade C with 54 points. Within-group changes or a historical simple difference are not adjusted between-group effects; maintenance is not a minimum starting dose. Create no new numbers, CIs, totals, grades, independence/safety certification or exercise, breathing, medication or treatment instructions.
Referenced methods: Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.

Related sources S01

N19 · Are maintenance and long-term persistence verified?

Current findings: Distinguish initial training 3 times weekly for 12 weeks from later maintenance 1 time weekly.
Verification status: Unverified
Materials actually read: Stored summary read; external abstracts, full texts, registration, protocols, SAPs and support disclosures unread
Why unverified: The selected claim, parent material and reports are distinguished and transferred from the stored summary. Detailed original material is unverified and review of existing content remains incomplete. This does not establish completed clinical review or certification.
Reason for missing information: Exact maintenance/long-term effects, denominators, comparisons and data for other ages or treated people are needed. Propose no new minimum exercise dose.
Required materials and conditions: Initial, maintenance and long-term results, populations, denominators and comparisons
Materials to obtain first: Exact maintenance/long-term effects, denominators, comparisons and data for other ages or treated people are needed. Propose no new minimum exercise dose.
Further research: Material needed: Exact maintenance/long-term effects, denominators, comparisons and data for other ages or treated people are needed. Propose no new minimum exercise dose. This records needed materials; no new research was executed.
Remaining uncertainty: External original material is unread and review of existing content remains incomplete. Original grades, scores, axes, historical verification and independence statements are not treated as new verdicts or certification.
Conditions for verification: Material for Initial, maintenance and long-term results, populations, denominators and comparisons must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.
Why this condition is needed: This condition connects Initial, maintenance and long-term results, populations, denominators and comparisons with selected 12-week resting systolic pressure, within- versus between-group comparisons, initial training versus maintenance, and measurement, denominator, support and harm boundaries.
Application exceptions: Preserve selected subclaim C and its within-group -12.9 mmHg note. Distinguish absent subclaim score/status/axes from parent grade C with 54 points. Within-group changes or a historical simple difference are not adjusted between-group effects; maintenance is not a minimum starting dose. Create no new numbers, CIs, totals, grades, independence/safety certification or exercise, breathing, medication or treatment instructions.
Referenced methods: Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.

Related sources S01

N20 · Are actual delivery, coactivity and adherence verified?

Current findings: Untreated adults, supervision, angle and intensity are original research conditions.
Verification status: Unverified
Materials actually read: Stored summary read; external abstracts, full texts, registration, protocols, SAPs and support disclosures unread
Why unverified: The selected claim, parent material and reports are distinguished and transferred from the stored summary. Detailed original material is unverified and review of existing content remains incomplete. This does not establish completed clinical review or certification.
Reason for missing information: Arm-specific coactivity/changes, actual training, supervision and adherence are needed. Give no personal exercise or medication policy.
Required materials and conditions: Concurrent exercise, medication/lifestyle changes, supervision, delivery and data attribution
Materials to obtain first: Arm-specific coactivity/changes, actual training, supervision and adherence are needed. Give no personal exercise or medication policy.
Further research: Material needed: Arm-specific coactivity/changes, actual training, supervision and adherence are needed. Give no personal exercise or medication policy. This records needed materials; no new research was executed.
Remaining uncertainty: External original material is unread and review of existing content remains incomplete. Original grades, scores, axes, historical verification and independence statements are not treated as new verdicts or certification.
Conditions for verification: Material for Concurrent exercise, medication/lifestyle changes, supervision, delivery and data attribution must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.
Why this condition is needed: This condition connects Concurrent exercise, medication/lifestyle changes, supervision, delivery and data attribution with selected 12-week resting systolic pressure, within- versus between-group comparisons, initial training versus maintenance, and measurement, denominator, support and harm boundaries.
Application exceptions: Preserve selected subclaim C and its within-group -12.9 mmHg note. Distinguish absent subclaim score/status/axes from parent grade C with 54 points. Within-group changes or a historical simple difference are not adjusted between-group effects; maintenance is not a minimum starting dose. Create no new numbers, CIs, totals, grades, independence/safety certification or exercise, breathing, medication or treatment instructions.
Referenced methods: Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.

Related sources S01

N21 · What are Cohen’s public funding and COI declarations?

Current findings: Preserve Cohen’s Colombian Ministry of Science/Colciencias support and declaration of no COI.
Verification status: Partly verified
Materials actually read: Stored summary read; external abstracts, full texts, registration, protocols, SAPs and support disclosures unread
Why unverified: The selected claim, parent material and reports are distinguished and transferred from the stored summary. Detailed original material is unverified and review of existing content remains incomplete. This does not establish completed clinical review or certification.
Reason for missing information: Original support/product, employed-author, analysis/publication-control and declaration materials are unread. Parent independent-funding wording is not new certification.
Required materials and conditions: Funding, product support, employed authors, analysis/publication roles and COI
Materials to obtain first: Original support/product, employed-author, analysis/publication-control and declaration materials are unread. Parent independent-funding wording is not new certification.
Further research: Material needed: Original support/product, employed-author, analysis/publication-control and declaration materials are unread. Parent independent-funding wording is not new certification. This records needed materials; no new research was executed.
Remaining uncertainty: External original material is unread and review of existing content remains incomplete. Original grades, scores, axes, historical verification and independence statements are not treated as new verdicts or certification.
Conditions for verification: Material for Funding, product support, employed authors, analysis/publication roles and COI must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.
Why this condition is needed: This condition connects Funding, product support, employed authors, analysis/publication roles and COI with selected 12-week resting systolic pressure, within- versus between-group comparisons, initial training versus maintenance, and measurement, denominator, support and harm boundaries.
Application exceptions: Preserve selected subclaim C and its within-group -12.9 mmHg note. Distinguish absent subclaim score/status/axes from parent grade C with 54 points. Within-group changes or a historical simple difference are not adjusted between-group effects; maintenance is not a minimum starting dose. Create no new numbers, CIs, totals, grades, independence/safety certification or exercise, breathing, medication or treatment instructions.
Referenced methods: Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.

Related sources S01

N22 · Is Decaux’s funding verified?

Current findings: Decaux’s original record states funding information was not provided.
Verification status: Unverified
Materials actually read: Stored summary read; external abstracts, full texts, registration, protocols, SAPs and support disclosures unread
Why unverified: The selected claim, parent material and reports are distinguished and transferred from the stored summary. Detailed original material is unverified and review of existing content remains incomplete. This does not establish completed clinical review or certification.
Reason for missing information: There is no material to fill this as no funding, independent support, no employed authors or no COI.
Required materials and conditions: Separate funding, support, employed-author and interest materials
Materials to obtain first: There is no material to fill this as no funding, independent support, no employed authors or no COI.
Further research: Material needed: There is no material to fill this as no funding, independent support, no employed authors or no COI. This records needed materials; no new research was executed.
Remaining uncertainty: External original material is unread and review of existing content remains incomplete. Original grades, scores, axes, historical verification and independence statements are not treated as new verdicts or certification.
Conditions for verification: Material for Separate funding, support, employed-author and interest materials must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.
Why this condition is needed: This condition connects Separate funding, support, employed-author and interest materials with selected 12-week resting systolic pressure, within- versus between-group comparisons, initial training versus maintenance, and measurement, denominator, support and harm boundaries.
Application exceptions: Preserve selected subclaim C and its within-group -12.9 mmHg note. Distinguish absent subclaim score/status/axes from parent grade C with 54 points. Within-group changes or a historical simple difference are not adjusted between-group effects; maintenance is not a minimum starting dose. Create no new numbers, CIs, totals, grades, independence/safety certification or exercise, breathing, medication or treatment instructions.
Referenced methods: Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.

Related sources S02

N23 · Do 0 reported adverse events guarantee safety?

Current findings: Preserve all 77 key-trial participants completed and 0 reported adverse events. This is a limited supervised sample.
Verification status: Partly verified
Materials actually read: Stored summary read; external abstracts, full texts, registration, protocols, SAPs and support disclosures unread
Why unverified: The selected claim, parent material and reports are distinguished and transferred from the stored summary. Detailed original material is unverified and review of existing content remains incomplete. This does not establish completed clinical review or certification.
Reason for missing information: Collection, arm exposure/denominators, severity, missingness, discontinuation and long-term harms are needed. Do not turn 0 into new safety certification.
Required materials and conditions: Harm definitions, collection, arm exposure/denominators, discontinuation and missingness
Materials to obtain first: Collection, arm exposure/denominators, severity, missingness, discontinuation and long-term harms are needed. Do not turn 0 into new safety certification.
Further research: Material needed: Collection, arm exposure/denominators, severity, missingness, discontinuation and long-term harms are needed. Do not turn 0 into new safety certification. This records needed materials; no new research was executed.
Remaining uncertainty: External original material is unread and review of existing content remains incomplete. Original grades, scores, axes, historical verification and independence statements are not treated as new verdicts or certification.
Conditions for verification: Material for Harm definitions, collection, arm exposure/denominators, discontinuation and missingness must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.
Why this condition is needed: This condition connects Harm definitions, collection, arm exposure/denominators, discontinuation and missingness with selected 12-week resting systolic pressure, within- versus between-group comparisons, initial training versus maintenance, and measurement, denominator, support and harm boundaries.
Application exceptions: Preserve selected subclaim C and its within-group -12.9 mmHg note. Distinguish absent subclaim score/status/axes from parent grade C with 54 points. Within-group changes or a historical simple difference are not adjusted between-group effects; maintenance is not a minimum starting dose. Create no new numbers, CIs, totals, grades, independence/safety certification or exercise, breathing, medication or treatment instructions.
Referenced methods: Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.

Related sources S01

N24 · Are acute and longer-term resting pressure the same?

Current findings: Parent records mean 196/112 mmHg during a separate acute 90° hold. This is not the 12-week resting value.
Verification status: Partly verified
Materials actually read: Stored summary read; external abstracts, full texts, registration, protocols, SAPs and support disclosures unread
Why unverified: The selected claim, parent material and reports are distinguished and transferred from the stored summary. Detailed original material is unverified and review of existing content remains incomplete. This does not establish completed clinical review or certification.
Reason for missing information: That acute study’s bibliography, population, denominators and measurement/exposure details are not linked. Do not borrow the other trials’ denominators or create a hypothetical report.
Required materials and conditions: Acute holds, resting results, bibliography, population and denominators
Materials to obtain first: That acute study’s bibliography, population, denominators and measurement/exposure details are not linked. Do not borrow the other trials’ denominators or create a hypothetical report.
Further research: Material needed: That acute study’s bibliography, population, denominators and measurement/exposure details are not linked. Do not borrow the other trials’ denominators or create a hypothetical report. This records needed materials; no new research was executed.
Remaining uncertainty: External original material is unread and review of existing content remains incomplete. Original grades, scores, axes, historical verification and independence statements are not treated as new verdicts or certification.
Conditions for verification: Material for Acute holds, resting results, bibliography, population and denominators must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.
Why this condition is needed: This condition connects Acute holds, resting results, bibliography, population and denominators with selected 12-week resting systolic pressure, within- versus between-group comparisons, initial training versus maintenance, and measurement, denominator, support and harm boundaries.
Application exceptions: Preserve selected subclaim C and its within-group -12.9 mmHg note. Distinguish absent subclaim score/status/axes from parent grade C with 54 points. Within-group changes or a historical simple difference are not adjusted between-group effects; maintenance is not a minimum starting dose. Create no new numbers, CIs, totals, grades, independence/safety certification or exercise, breathing, medication or treatment instructions.
Referenced methods: Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.

Related sources S01 S02

N25 · Are long-term and vulnerable-population harms verified?

Current findings: Preserve parent caution and the acute/resting timing distinction. Give no new exercise, breathing, medication reduction/replacement or treatment instructions.
Verification status: Unverified
Materials actually read: Stored summary read; external abstracts, full texts, registration, protocols, SAPs and support disclosures unread
Why unverified: The selected claim, parent material and reports are distinguished and transferred from the stored summary. Detailed original material is unverified and review of existing content remains incomplete. This does not establish completed clinical review or certification.
Reason for missing information: Population/exposure-specific long-term harms, alternative causes and discontinuation materials are needed. Do not extend a small supervised sample into safety certification for other populations or unsupervised settings.
Required materials and conditions: Supervision, exposure, vulnerable populations, concurrent factors and long-term harms
Materials to obtain first: Population/exposure-specific long-term harms, alternative causes and discontinuation materials are needed. Do not extend a small supervised sample into safety certification for other populations or unsupervised settings.
Further research: Material needed: Population/exposure-specific long-term harms, alternative causes and discontinuation materials are needed. Do not extend a small supervised sample into safety certification for other populations or unsupervised settings. This records needed materials; no new research was executed.
Remaining uncertainty: External original material is unread and review of existing content remains incomplete. Original grades, scores, axes, historical verification and independence statements are not treated as new verdicts or certification.
Conditions for verification: Material for Supervision, exposure, vulnerable populations, concurrent factors and long-term harms must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.
Why this condition is needed: This condition connects Supervision, exposure, vulnerable populations, concurrent factors and long-term harms with selected 12-week resting systolic pressure, within- versus between-group comparisons, initial training versus maintenance, and measurement, denominator, support and harm boundaries.
Application exceptions: Preserve selected subclaim C and its within-group -12.9 mmHg note. Distinguish absent subclaim score/status/axes from parent grade C with 54 points. Within-group changes or a historical simple difference are not adjusted between-group effects; maintenance is not a minimum starting dose. Create no new numbers, CIs, totals, grades, independence/safety certification or exercise, breathing, medication or treatment instructions.
Referenced methods: Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.

Related sources S01 S02

N26 · How are original verdicts, dates and corrections preserved?

Current findings: Preserve parent grade C with 54 points, both languages, axes, 2026-09-07, empty corrections and deliberation string, selected C/note and absent subclaim score/status/axes.
Verification status: Partly verified
Materials actually read: Stored summary read; external abstracts, full texts, registration, protocols, SAPs and support disclosures unread
Why unverified: The selected claim, parent material and reports are distinguished and transferred from the stored summary. Detailed original material is unverified and review of existing content remains incomplete. This does not establish completed clinical review or certification.
Reason for missing information: Historical key/sham, funding and acute-verification wording is not current review or clinical certification. Create no new grades, effects or hypothetical numbers.
Required materials and conditions: Parent/subclaim grades, scores, axes, both languages, dates and absent values
Materials to obtain first: Historical key/sham, funding and acute-verification wording is not current review or clinical certification. Create no new grades, effects or hypothetical numbers.
Further research: Material needed: Historical key/sham, funding and acute-verification wording is not current review or clinical certification. Create no new grades, effects or hypothetical numbers. This records needed materials; no new research was executed.
Remaining uncertainty: External original material is unread and review of existing content remains incomplete. Original grades, scores, axes, historical verification and independence statements are not treated as new verdicts or certification.
Conditions for verification: Material for Parent/subclaim grades, scores, axes, both languages, dates and absent values must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.
Why this condition is needed: This condition connects Parent/subclaim grades, scores, axes, both languages, dates and absent values with selected 12-week resting systolic pressure, within- versus between-group comparisons, initial training versus maintenance, and measurement, denominator, support and harm boundaries.
Application exceptions: Preserve selected subclaim C and its within-group -12.9 mmHg note. Distinguish absent subclaim score/status/axes from parent grade C with 54 points. Within-group changes or a historical simple difference are not adjusted between-group effects; maintenance is not a minimum starting dose. Create no new numbers, CIs, totals, grades, independence/safety certification or exercise, breathing, medication or treatment instructions.
Referenced methods: Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.

Related sources S01 S02

N27 · What material was actually read?

Current findings: The complete stored summary and bibliography were used. Distinguish reading the stored summary from unread external material.
Verification status: Partly verified
Materials actually read: Stored summary read; external abstracts, full texts, registration, protocols, SAPs and support disclosures unread
Why unverified: The selected claim, parent material and reports are distinguished and transferred from the stored summary. Detailed original material is unverified and review of existing content remains incomplete. This does not establish completed clinical review or certification.
Reason for missing information: External papers, registration, protocols, SAPs, support and acute originals are unread; access was not attempted. Links or historical verification do not establish current reading.
Required materials and conditions: Report/material links and paper, registration, plan and support states
Materials to obtain first: External papers, registration, protocols, SAPs, support and acute originals are unread; access was not attempted. Links or historical verification do not establish current reading.
Further research: Material needed: External papers, registration, protocols, SAPs, support and acute originals are unread; access was not attempted. Links or historical verification do not establish current reading. This records needed materials; no new research was executed.
Remaining uncertainty: External original material is unread and review of existing content remains incomplete. Original grades, scores, axes, historical verification and independence statements are not treated as new verdicts or certification.
Conditions for verification: Material for Report/material links and paper, registration, plan and support states must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.
Why this condition is needed: This condition connects Report/material links and paper, registration, plan and support states with selected 12-week resting systolic pressure, within- versus between-group comparisons, initial training versus maintenance, and measurement, denominator, support and harm boundaries.
Application exceptions: Preserve selected subclaim C and its within-group -12.9 mmHg note. Distinguish absent subclaim score/status/axes from parent grade C with 54 points. Within-group changes or a historical simple difference are not adjusted between-group effects; maintenance is not a minimum starting dose. Create no new numbers, CIs, totals, grades, independence/safety certification or exercise, breathing, medication or treatment instructions.
Referenced methods: Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.

Related sources S01 S02