{
  "schema_version": "chamgap-public-criteria-1.0",
  "title": "Supervised wall sits × lower resting SBP at 12 weeks",
  "language": "en",
  "translation_date": "2026-10-16",
  "criteria_version": "1.0",
  "criteria_date": "2026-10-06",
  "condition_origin": "Chamgap's own application conditions",
  "method_sources": [
    {
      "id": "M03",
      "version": "Cochrane Handbook 6.5 (2024), chapter updated 2023-08",
      "url": "https://www.cochrane.org/authors/handbooks-and-manuals/handbook/current/chapter-03",
      "section": "§3.1, §3.2.1–3.2.3, MECIR C5/C7/C13",
      "official_principle": "Clearly record the question, eligibility conditions and reasons for changes, and distinguish variations in interventions.",
      "review_level": "Existing methodological links were reused for production. External originals were not reread and methodological content was not reassessed."
    },
    {
      "id": "M04",
      "version": "Cochrane Handbook 6.5.1 (2025), chapter updated 2025-03",
      "url": "https://www.cochrane.org/authors/handbooks-and-manuals/handbook/current/chapter-04",
      "section": "§4.5, §4.6.1–4.6.3, MECIR C42",
      "official_principle": "Distinguish studies from reports and link them; do not omit a study solely because results are unreported.",
      "review_level": "Existing methodological links were reused for production. External originals were not reread and methodological content was not reassessed."
    },
    {
      "id": "M08",
      "version": "Cochrane Handbook 6.5 (2024), chapter updated 2019-10",
      "url": "https://www.cochrane.org/authors/handbooks-and-manuals/handbook/current/chapter-08",
      "section": "§8.1–8.2.3, Table 8.2.a",
      "official_principle": "Define the outcome and effect of interest, then examine randomization, deviations, missing data, measurement and selective reporting.",
      "review_level": "Existing methodological links were reused for production. External originals were not reread and methodological content was not reassessed."
    },
    {
      "id": "M15",
      "version": "Cochrane Handbook 6.5 (2024), chapter updated 2023-08",
      "url": "https://www.cochrane.org/authors/handbooks-and-manuals/handbook/current/chapter-15",
      "section": "§15.2.4, §15.3.1–15.3.3",
      "official_principle": "Distinguish effect estimates, intervals, importance and applicability. Sample size alone does not determine precision.",
      "review_level": "Existing methodological links were reused for production. External originals were not reread and methodological content was not reassessed."
    },
    {
      "id": "M19",
      "version": "Cochrane Handbook 6.5 (2024), chapter updated 2019-10",
      "url": "https://www.cochrane.org/authors/handbooks-and-manuals/handbook/current/chapter-19",
      "section": "§19.1.2, §19.2.1–19.2.4",
      "official_principle": "Harm questions may require different designs, populations and follow-up from efficacy questions. Case reports do not establish incidence rates.",
      "review_level": "Existing methodological links were reused for production. External originals were not reread and methodological content was not reassessed."
    }
  ],
  "status_dictionary": {
    "Met": "A state used when required evidence is confirmed after user review. This production does not declare that review complete.",
    "Partly verified": "Some information in the stored summary is linked into the table. External comparison/content review is not complete.",
    "Unverified": "The article leaves this unverified, or required material is absent from the current stored summary. This is distinct from zero, absence or safety.",
    "Review incomplete": "User review pending.",
    "Not reported": "Not reported within the stored material actually read; not extended to the entire primary paper.",
    "Inaccessible": "Means an actual access failure. Access not attempted here is not assigned this state.",
    "Not applicable": "Not used as a substitute for an evidence gap.",
    "Conflicting data": "Requires an observed disagreement under the same comparison criteria; not automatically judged in this production.",
    "Insufficient evidence for the conditions": "Marks a gap in additional material required by the selected conditions; not a new efficacy grade."
  },
  "requirements": [
    {
      "item_id": "N01",
      "question_type": "Evidence condition",
      "question": "What is the selected 12-week resting-SBP question?",
      "needed": "Exact subclaim, grade/note and parent verdict",
      "role": "Required",
      "role_reason": "This condition connects Exact subclaim, grade/note and parent verdict with selected 12-week resting systolic pressure, within- versus between-group comparisons, initial training versus maintenance, and measurement, denominator, support and harm boundaries.",
      "application_exception": "Preserve selected subclaim C and its within-group -12.9 mmHg note. Distinguish absent subclaim score/status/axes from parent grade C with 54 points. Within-group changes or a historical simple difference are not adjusted between-group effects; maintenance is not a minimum starting dose. Create no new numbers, CIs, totals, grades, independence/safety certification or exercise, breathing, medication or treatment instructions.",
      "criterion": "Material for Exact subclaim, grade/note and parent verdict must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.",
      "basis": "Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.",
      "condition_origin": "Internally applied conditions preserved for the existing subclaim. They do not establish preregistration, official-tool certification or completed content review.",
      "proposed_research": "Material needed: The subclaim has no score, status or axis fields. Do not fill them with parent values. This records needed materials; no new research was executed."
    },
    {
      "item_id": "N02",
      "question_type": "Evidence condition",
      "question": "Which adults with hypertension participated?",
      "needed": "Diagnosis, age, medication status, baseline risk and eligibility",
      "role": "Required",
      "role_reason": "This condition connects Diagnosis, age, medication status, baseline risk and eligibility with selected 12-week resting systolic pressure, within- versus between-group comparisons, initial training versus maintenance, and measurement, denominator, support and harm boundaries.",
      "application_exception": "Preserve selected subclaim C and its within-group -12.9 mmHg note. Distinguish absent subclaim score/status/axes from parent grade C with 54 points. Within-group changes or a historical simple difference are not adjusted between-group effects; maintenance is not a minimum starting dose. Create no new numbers, CIs, totals, grades, independence/safety certification or exercise, breathing, medication or treatment instructions.",
      "criterion": "Material for Diagnosis, age, medication status, baseline risk and eligibility must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.",
      "basis": "Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.",
      "condition_origin": "Internally applied conditions preserved for the existing subclaim. They do not establish preregistration, official-tool certification or completed content review.",
      "proposed_research": "Material needed: Exact diagnosis, baseline severity, eligibility/exclusions, sex, comorbidities and recruitment details are needed. Do not extend to treated people or other ages. This records needed materials; no new research was executed."
    },
    {
      "item_id": "N03",
      "question_type": "Evidence condition",
      "question": "What was the supervised wall-sit intervention?",
      "needed": "Supervision, knee angle, intensity calibration, actual delivery and components",
      "role": "Required",
      "role_reason": "This condition connects Supervision, knee angle, intensity calibration, actual delivery and components with selected 12-week resting systolic pressure, within- versus between-group comparisons, initial training versus maintenance, and measurement, denominator, support and harm boundaries.",
      "application_exception": "Preserve selected subclaim C and its within-group -12.9 mmHg note. Distinguish absent subclaim score/status/axes from parent grade C with 54 points. Within-group changes or a historical simple difference are not adjusted between-group effects; maintenance is not a minimum starting dose. Create no new numbers, CIs, totals, grades, independence/safety certification or exercise, breathing, medication or treatment instructions.",
      "criterion": "Material for Supervision, knee angle, intensity calibration, actual delivery and components must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.",
      "basis": "Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.",
      "condition_origin": "Internally applied conditions preserved for the existing subclaim. They do not establish preregistration, official-tool certification or completed content review.",
      "proposed_research": "Material needed: Individual settings, supervision, actual delivery and adherence are needed. Research conditions are not new exercise instructions. This records needed materials; no new research was executed."
    },
    {
      "item_id": "N04",
      "question_type": "Evidence condition",
      "question": "How do initial training and maintenance differ?",
      "needed": "Separate attribution of initial/maintenance schedules and analyses",
      "role": "Required",
      "role_reason": "This condition connects Separate attribution of initial/maintenance schedules and analyses with selected 12-week resting systolic pressure, within- versus between-group comparisons, initial training versus maintenance, and measurement, denominator, support and harm boundaries.",
      "application_exception": "Preserve selected subclaim C and its within-group -12.9 mmHg note. Distinguish absent subclaim score/status/axes from parent grade C with 54 points. Within-group changes or a historical simple difference are not adjusted between-group effects; maintenance is not a minimum starting dose. Create no new numbers, CIs, totals, grades, independence/safety certification or exercise, breathing, medication or treatment instructions.",
      "criterion": "Material for Separate attribution of initial/maintenance schedules and analyses must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.",
      "basis": "Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.",
      "condition_origin": "Internally applied conditions preserved for the existing subclaim. They do not establish preregistration, official-tool certification or completed content review.",
      "proposed_research": "Material needed: Maintenance allocation, duration, denominators and detailed results are needed. Do not transfer maintenance into a minimum starting dose. This records needed materials; no new research was executed."
    },
    {
      "item_id": "N05",
      "question_type": "Evidence condition",
      "question": "What were the actual comparators?",
      "needed": "Wall sit versus no exercise and the scope of the other exercise arm",
      "role": "Required",
      "role_reason": "This condition connects Wall sit versus no exercise and the scope of the other exercise arm with selected 12-week resting systolic pressure, within- versus between-group comparisons, initial training versus maintenance, and measurement, denominator, support and harm boundaries.",
      "application_exception": "Preserve selected subclaim C and its within-group -12.9 mmHg note. Distinguish absent subclaim score/status/axes from parent grade C with 54 points. Within-group changes or a historical simple difference are not adjusted between-group effects; maintenance is not a minimum starting dose. Create no new numbers, CIs, totals, grades, independence/safety certification or exercise, breathing, medication or treatment instructions.",
      "criterion": "Material for Wall sit versus no exercise and the scope of the other exercise arm must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.",
      "basis": "Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.",
      "condition_origin": "Internally applied conditions preserved for the existing subclaim. They do not establish preregistration, official-tool certification or completed content review.",
      "proposed_research": "Material needed: Arm allocation, denominators, contact, expectations and usual activity are needed. Do not combine handgrip with the wall-sit intervention. This records needed materials; no new research was executed."
    },
    {
      "item_id": "N06",
      "question_type": "Evidence condition",
      "question": "Does complete follow-up establish endpoint denominators?",
      "needed": "Overall allocation/completion versus arm denominators, missing measurements and analysis rules",
      "role": "Required",
      "role_reason": "This condition connects Overall allocation/completion versus arm denominators, missing measurements and analysis rules with selected 12-week resting systolic pressure, within- versus between-group comparisons, initial training versus maintenance, and measurement, denominator, support and harm boundaries.",
      "application_exception": "Preserve selected subclaim C and its within-group -12.9 mmHg note. Distinguish absent subclaim score/status/axes from parent grade C with 54 points. Within-group changes or a historical simple difference are not adjusted between-group effects; maintenance is not a minimum starting dose. Create no new numbers, CIs, totals, grades, independence/safety certification or exercise, breathing, medication or treatment instructions.",
      "criterion": "Material for Overall allocation/completion versus arm denominators, missing measurements and analysis rules must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.",
      "basis": "Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.",
      "condition_origin": "Internally applied conditions preserved for the existing subclaim. They do not establish preregistration, official-tool certification or completed content review.",
      "proposed_research": "Material needed: Wall-sit, no-exercise and handgrip denominators, valid/missing measurements and analysis rules are needed. Completion does not establish complete measurement of every outcome. This records needed materials; no new research was executed."
    },
    {
      "item_id": "N07",
      "question_type": "Evidence condition",
      "question": "How was resting office SBP measured?",
      "needed": "Resting conditions, equipment, repetitions, assessor and timing",
      "role": "Required",
      "role_reason": "This condition connects Resting conditions, equipment, repetitions, assessor and timing with selected 12-week resting systolic pressure, within- versus between-group comparisons, initial training versus maintenance, and measurement, denominator, support and harm boundaries.",
      "application_exception": "Preserve selected subclaim C and its within-group -12.9 mmHg note. Distinguish absent subclaim score/status/axes from parent grade C with 54 points. Within-group changes or a historical simple difference are not adjusted between-group effects; maintenance is not a minimum starting dose. Create no new numbers, CIs, totals, grades, independence/safety certification or exercise, breathing, medication or treatment instructions.",
      "criterion": "Material for Resting conditions, equipment, repetitions, assessor and timing must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.",
      "basis": "Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.",
      "condition_origin": "Internally applied conditions preserved for the existing subclaim. They do not establish preregistration, official-tool certification or completed content review.",
      "proposed_research": "Material needed: Equipment, rest, repetitions, assessor blinding, standardization and medication/activity/time conditions are needed. Do not combine with in-exercise pressure. This records needed materials; no new research was executed."
    },
    {
      "item_id": "N08",
      "question_type": "Evidence condition",
      "question": "Which arms do baseline and final values describe?",
      "needed": "Original wall-sit/no-exercise values, units and baseline/final correspondence",
      "role": "Required",
      "role_reason": "This condition connects Original wall-sit/no-exercise values, units and baseline/final correspondence with selected 12-week resting systolic pressure, within- versus between-group comparisons, initial training versus maintenance, and measurement, denominator, support and harm boundaries.",
      "application_exception": "Preserve selected subclaim C and its within-group -12.9 mmHg note. Distinguish absent subclaim score/status/axes from parent grade C with 54 points. Within-group changes or a historical simple difference are not adjusted between-group effects; maintenance is not a minimum starting dose. Create no new numbers, CIs, totals, grades, independence/safety certification or exercise, breathing, medication or treatment instructions.",
      "criterion": "Material for Original wall-sit/no-exercise values, units and baseline/final correspondence must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.",
      "basis": "Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.",
      "condition_origin": "Internally applied conditions preserved for the existing subclaim. They do not establish preregistration, official-tool certification or completed content review.",
      "proposed_research": "Material needed: Arm denominators, variance, distributions, models and CIs are needed. Calculate no new difference, change or effect. This records needed materials; no new research was executed."
    },
    {
      "item_id": "N09",
      "question_type": "Evidence condition",
      "question": "What do within-group changes and P values mean?",
      "needed": "Within-group changes, tests, denominators and scope of estimation",
      "role": "Required",
      "role_reason": "This condition connects Within-group changes, tests, denominators and scope of estimation with selected 12-week resting systolic pressure, within- versus between-group comparisons, initial training versus maintenance, and measurement, denominator, support and harm boundaries.",
      "application_exception": "Preserve selected subclaim C and its within-group -12.9 mmHg note. Distinguish absent subclaim score/status/axes from parent grade C with 54 points. Within-group changes or a historical simple difference are not adjusted between-group effects; maintenance is not a minimum starting dose. Create no new numbers, CIs, totals, grades, independence/safety certification or exercise, breathing, medication or treatment instructions.",
      "criterion": "Material for Within-group changes, tests, denominators and scope of estimation must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.",
      "basis": "Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.",
      "condition_origin": "Internally applied conditions preserved for the existing subclaim. They do not establish preregistration, official-tool certification or completed content review.",
      "proposed_research": "Material needed: A within-group P value is not a between-group P value. Within-group CIs, variance, denominators and between-group tests are needed. This records needed materials; no new research was executed."
    },
    {
      "item_id": "N10",
      "question_type": "Evidence condition",
      "question": "Is the historical simple difference an adjusted effect?",
      "needed": "Original arithmetic wording versus adjusted between-group estimation",
      "role": "Required",
      "role_reason": "This condition connects Original arithmetic wording versus adjusted between-group estimation with selected 12-week resting systolic pressure, within- versus between-group comparisons, initial training versus maintenance, and measurement, denominator, support and harm boundaries.",
      "application_exception": "Preserve selected subclaim C and its within-group -12.9 mmHg note. Distinguish absent subclaim score/status/axes from parent grade C with 54 points. Within-group changes or a historical simple difference are not adjusted between-group effects; maintenance is not a minimum starting dose. Create no new numbers, CIs, totals, grades, independence/safety certification or exercise, breathing, medication or treatment instructions.",
      "criterion": "Material for Original arithmetic wording versus adjusted between-group estimation must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.",
      "basis": "Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.",
      "condition_origin": "Internally applied conditions preserved for the existing subclaim. They do not establish preregistration, official-tool certification or completed content review.",
      "proposed_research": "Material needed: Adjusted effects, models, exact between-group 95% CIs and P values are needed. Do not promote a historical value into a new estimate. This records needed materials; no new research was executed."
    },
    {
      "item_id": "N11",
      "question_type": "Evidence condition",
      "question": "Are endpoint hierarchy and registration verified?",
      "needed": "SBP/DBP, initial/maintenance, prospective 1st/2nd outcomes and changes",
      "role": "Required",
      "role_reason": "This condition connects SBP/DBP, initial/maintenance, prospective 1st/2nd outcomes and changes with selected 12-week resting systolic pressure, within- versus between-group comparisons, initial training versus maintenance, and measurement, denominator, support and harm boundaries.",
      "application_exception": "Preserve selected subclaim C and its within-group -12.9 mmHg note. Distinguish absent subclaim score/status/axes from parent grade C with 54 points. Within-group changes or a historical simple difference are not adjusted between-group effects; maintenance is not a minimum starting dose. Create no new numbers, CIs, totals, grades, independence/safety certification or exercise, breathing, medication or treatment instructions.",
      "criterion": "Material for SBP/DBP, initial/maintenance, prospective 1st/2nd outcomes and changes must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.",
      "basis": "Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.",
      "condition_origin": "Internally applied conditions preserved for the existing subclaim. They do not establish preregistration, official-tool certification or completed content review.",
      "proposed_research": "Material needed: Registration, protocols, SAPs, multiplicity and change history are unread. Do not fill an absent field as unregistered or not applicable. This records needed materials; no new research was executed."
    },
    {
      "item_id": "N12",
      "question_type": "Evidence condition",
      "question": "Are randomization and assessment roles verified?",
      "needed": "Allocation, concealment, multicenter structure, blinding and assessment/analysis roles",
      "role": "Required",
      "role_reason": "This condition connects Allocation, concealment, multicenter structure, blinding and assessment/analysis roles with selected 12-week resting systolic pressure, within- versus between-group comparisons, initial training versus maintenance, and measurement, denominator, support and harm boundaries.",
      "application_exception": "Preserve selected subclaim C and its within-group -12.9 mmHg note. Distinguish absent subclaim score/status/axes from parent grade C with 54 points. Within-group changes or a historical simple difference are not adjusted between-group effects; maintenance is not a minimum starting dose. Create no new numbers, CIs, totals, grades, independence/safety certification or exercise, breathing, medication or treatment instructions.",
      "criterion": "Material for Allocation, concealment, multicenter structure, blinding and assessment/analysis roles must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.",
      "basis": "Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.",
      "condition_origin": "Internally applied conditions preserved for the existing subclaim. They do not establish preregistration, official-tool certification or completed content review.",
      "proposed_research": "Material needed: Allocation concealment, center structure, participant/assessor/analyst blinding and expectations are needed. This records needed materials; no new research was executed."
    },
    {
      "item_id": "N13",
      "question_type": "Evidence condition",
      "question": "Are between-group analysis and missing-data handling verified?",
      "needed": "Estimand, baseline adjustment, ITT/PP, repeated/missing data and sensitivity analyses",
      "role": "Required",
      "role_reason": "This condition connects Estimand, baseline adjustment, ITT/PP, repeated/missing data and sensitivity analyses with selected 12-week resting systolic pressure, within- versus between-group comparisons, initial training versus maintenance, and measurement, denominator, support and harm boundaries.",
      "application_exception": "Preserve selected subclaim C and its within-group -12.9 mmHg note. Distinguish absent subclaim score/status/axes from parent grade C with 54 points. Within-group changes or a historical simple difference are not adjusted between-group effects; maintenance is not a minimum starting dose. Create no new numbers, CIs, totals, grades, independence/safety certification or exercise, breathing, medication or treatment instructions.",
      "criterion": "Material for Estimand, baseline adjustment, ITT/PP, repeated/missing data and sensitivity analyses must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.",
      "basis": "Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.",
      "condition_origin": "Internally applied conditions preserved for the existing subclaim. They do not establish preregistration, official-tool certification or completed content review.",
      "proposed_research": "Material needed: ITT/PP, valid/excluded measurements, center/repeated-measure models, covariates, missing data and sensitivity analyses are needed. This records needed materials; no new research was executed."
    },
    {
      "item_id": "N14",
      "question_type": "Evidence condition",
      "question": "How do SBP and DBP results differ?",
      "needed": "Values, denominators and prospective analysis for each pressure measure",
      "role": "Required",
      "role_reason": "This condition connects Values, denominators and prospective analysis for each pressure measure with selected 12-week resting systolic pressure, within- versus between-group comparisons, initial training versus maintenance, and measurement, denominator, support and harm boundaries.",
      "application_exception": "Preserve selected subclaim C and its within-group -12.9 mmHg note. Distinguish absent subclaim score/status/axes from parent grade C with 54 points. Within-group changes or a historical simple difference are not adjusted between-group effects; maintenance is not a minimum starting dose. Create no new numbers, CIs, totals, grades, independence/safety certification or exercise, breathing, medication or treatment instructions.",
      "criterion": "Material for Values, denominators and prospective analysis for each pressure measure must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.",
      "basis": "Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.",
      "condition_origin": "Internally applied conditions preserved for the existing subclaim. They do not establish preregistration, official-tool certification or completed content review.",
      "proposed_research": "Material needed: SBP does not substitute for DBP effects. Exact original DBP values, CIs and analyses are needed. This records needed materials; no new research was executed."
    },
    {
      "item_id": "N15",
      "question_type": "Evidence condition",
      "question": "What does the separate 4-week sham trial show?",
      "needed": "Population, intensity, comparators, duration and each pressure outcome",
      "role": "Required",
      "role_reason": "This condition connects Population, intensity, comparators, duration and each pressure outcome with selected 12-week resting systolic pressure, within- versus between-group comparisons, initial training versus maintenance, and measurement, denominator, support and harm boundaries.",
      "application_exception": "Preserve selected subclaim C and its within-group -12.9 mmHg note. Distinguish absent subclaim score/status/axes from parent grade C with 54 points. Within-group changes or a historical simple difference are not adjusted between-group effects; maintenance is not a minimum starting dose. Create no new numbers, CIs, totals, grades, independence/safety certification or exercise, breathing, medication or treatment instructions.",
      "criterion": "Material for Population, intensity, comparators, duration and each pressure outcome must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.",
      "basis": "Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.",
      "condition_origin": "Internally applied conditions preserved for the existing subclaim. They do not establish preregistration, official-tool certification or completed content review.",
      "proposed_research": "Material needed: The variance type for ±, arm denominators, original changes/models, comparator-specific contrasts and CIs are needed. Do not turn this into the same 12-week effect or independent confirmation. This records needed materials; no new research was executed."
    },
    {
      "item_id": "N16",
      "question_type": "Evidence condition",
      "question": "Are registration identifiers distinct from prospective materials?",
      "needed": "Citation identifier, absent evidence-summary field and prospective plans",
      "role": "Required",
      "role_reason": "This condition connects Citation identifier, absent evidence-summary field and prospective plans with selected 12-week resting systolic pressure, within- versus between-group comparisons, initial training versus maintenance, and measurement, denominator, support and harm boundaries.",
      "application_exception": "Preserve selected subclaim C and its within-group -12.9 mmHg note. Distinguish absent subclaim score/status/axes from parent grade C with 54 points. Within-group changes or a historical simple difference are not adjusted between-group effects; maintenance is not a minimum starting dose. Create no new numbers, CIs, totals, grades, independence/safety certification or exercise, breathing, medication or treatment instructions.",
      "criterion": "Material for Citation identifier, absent evidence-summary field and prospective plans must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.",
      "basis": "Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.",
      "condition_origin": "Internally applied conditions preserved for the existing subclaim. They do not establish preregistration, official-tool certification or completed content review.",
      "proposed_research": "Material needed: Registration timing, changes, prospective endpoints, protocols and SAPs are unread. An identifier alone does not certify prospective status or independence. This records needed materials; no new research was executed."
    },
    {
      "item_id": "N17",
      "question_type": "Evidence condition",
      "question": "Are replication and report/sample relationships verified?",
      "needed": "Duration, intervention, comparator, support, shared samples and related reports",
      "role": "Required",
      "role_reason": "This condition connects Duration, intervention, comparator, support, shared samples and related reports with selected 12-week resting systolic pressure, within- versus between-group comparisons, initial training versus maintenance, and measurement, denominator, support and harm boundaries.",
      "application_exception": "Preserve selected subclaim C and its within-group -12.9 mmHg note. Distinguish absent subclaim score/status/axes from parent grade C with 54 points. Within-group changes or a historical simple difference are not adjusted between-group effects; maintenance is not a minimum starting dose. Create no new numbers, CIs, totals, grades, independence/safety certification or exercise, breathing, medication or treatment instructions.",
      "criterion": "Material for Duration, intervention, comparator, support, shared samples and related reports must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.",
      "basis": "Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.",
      "condition_origin": "Internally applied conditions preserved for the existing subclaim. They do not establish preregistration, official-tool certification or completed content review.",
      "proposed_research": "Material needed: Independent confirmation under the same conditions and unique-trial/participant or replication totals remain unverified. Reports, times, arms and sheets are not new clinical totals. This records needed materials; no new research was executed."
    },
    {
      "item_id": "N18",
      "question_type": "Evidence condition",
      "question": "Does resting pressure establish medication replacement or event prevention?",
      "needed": "Surrogate, medication comparison, treatment replacement and cardiovascular-event boundaries",
      "role": "Required",
      "role_reason": "This condition connects Surrogate, medication comparison, treatment replacement and cardiovascular-event boundaries with selected 12-week resting systolic pressure, within- versus between-group comparisons, initial training versus maintenance, and measurement, denominator, support and harm boundaries.",
      "application_exception": "Preserve selected subclaim C and its within-group -12.9 mmHg note. Distinguish absent subclaim score/status/axes from parent grade C with 54 points. Within-group changes or a historical simple difference are not adjusted between-group effects; maintenance is not a minimum starting dose. Create no new numbers, CIs, totals, grades, independence/safety certification or exercise, breathing, medication or treatment instructions.",
      "criterion": "Material for Surrogate, medication comparison, treatment replacement and cardiovascular-event boundaries must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.",
      "basis": "Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.",
      "condition_origin": "Internally applied conditions preserved for the existing subclaim. They do not establish preregistration, official-tool certification or completed content review.",
      "proposed_research": "Material needed: Do not transfer SBP into medication equivalence, dose reduction/replacement, heart-attack prevention or long-term clinical effects. Create no treatment instructions. This records needed materials; no new research was executed."
    },
    {
      "item_id": "N19",
      "question_type": "Evidence condition",
      "question": "Are maintenance and long-term persistence verified?",
      "needed": "Initial, maintenance and long-term results, populations, denominators and comparisons",
      "role": "Required",
      "role_reason": "This condition connects Initial, maintenance and long-term results, populations, denominators and comparisons with selected 12-week resting systolic pressure, within- versus between-group comparisons, initial training versus maintenance, and measurement, denominator, support and harm boundaries.",
      "application_exception": "Preserve selected subclaim C and its within-group -12.9 mmHg note. Distinguish absent subclaim score/status/axes from parent grade C with 54 points. Within-group changes or a historical simple difference are not adjusted between-group effects; maintenance is not a minimum starting dose. Create no new numbers, CIs, totals, grades, independence/safety certification or exercise, breathing, medication or treatment instructions.",
      "criterion": "Material for Initial, maintenance and long-term results, populations, denominators and comparisons must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.",
      "basis": "Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.",
      "condition_origin": "Internally applied conditions preserved for the existing subclaim. They do not establish preregistration, official-tool certification or completed content review.",
      "proposed_research": "Material needed: Exact maintenance/long-term effects, denominators, comparisons and data for other ages or treated people are needed. Propose no new minimum exercise dose. This records needed materials; no new research was executed."
    },
    {
      "item_id": "N20",
      "question_type": "Evidence condition",
      "question": "Are actual delivery, coactivity and adherence verified?",
      "needed": "Concurrent exercise, medication/lifestyle changes, supervision, delivery and data attribution",
      "role": "Supplementary",
      "role_reason": "This condition connects Concurrent exercise, medication/lifestyle changes, supervision, delivery and data attribution with selected 12-week resting systolic pressure, within- versus between-group comparisons, initial training versus maintenance, and measurement, denominator, support and harm boundaries.",
      "application_exception": "Preserve selected subclaim C and its within-group -12.9 mmHg note. Distinguish absent subclaim score/status/axes from parent grade C with 54 points. Within-group changes or a historical simple difference are not adjusted between-group effects; maintenance is not a minimum starting dose. Create no new numbers, CIs, totals, grades, independence/safety certification or exercise, breathing, medication or treatment instructions.",
      "criterion": "Material for Concurrent exercise, medication/lifestyle changes, supervision, delivery and data attribution must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.",
      "basis": "Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.",
      "condition_origin": "Internally applied conditions preserved for the existing subclaim. They do not establish preregistration, official-tool certification or completed content review.",
      "proposed_research": "Material needed: Arm-specific coactivity/changes, actual training, supervision and adherence are needed. Give no personal exercise or medication policy. This records needed materials; no new research was executed."
    },
    {
      "item_id": "N21",
      "question_type": "Evidence condition",
      "question": "What are Cohen’s public funding and COI declarations?",
      "needed": "Funding, product support, employed authors, analysis/publication roles and COI",
      "role": "Required",
      "role_reason": "This condition connects Funding, product support, employed authors, analysis/publication roles and COI with selected 12-week resting systolic pressure, within- versus between-group comparisons, initial training versus maintenance, and measurement, denominator, support and harm boundaries.",
      "application_exception": "Preserve selected subclaim C and its within-group -12.9 mmHg note. Distinguish absent subclaim score/status/axes from parent grade C with 54 points. Within-group changes or a historical simple difference are not adjusted between-group effects; maintenance is not a minimum starting dose. Create no new numbers, CIs, totals, grades, independence/safety certification or exercise, breathing, medication or treatment instructions.",
      "criterion": "Material for Funding, product support, employed authors, analysis/publication roles and COI must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.",
      "basis": "Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.",
      "condition_origin": "Internally applied conditions preserved for the existing subclaim. They do not establish preregistration, official-tool certification or completed content review.",
      "proposed_research": "Material needed: Original support/product, employed-author, analysis/publication-control and declaration materials are unread. Parent independent-funding wording is not new certification. This records needed materials; no new research was executed."
    },
    {
      "item_id": "N22",
      "question_type": "Evidence condition",
      "question": "Is Decaux’s funding verified?",
      "needed": "Separate funding, support, employed-author and interest materials",
      "role": "Required",
      "role_reason": "This condition connects Separate funding, support, employed-author and interest materials with selected 12-week resting systolic pressure, within- versus between-group comparisons, initial training versus maintenance, and measurement, denominator, support and harm boundaries.",
      "application_exception": "Preserve selected subclaim C and its within-group -12.9 mmHg note. Distinguish absent subclaim score/status/axes from parent grade C with 54 points. Within-group changes or a historical simple difference are not adjusted between-group effects; maintenance is not a minimum starting dose. Create no new numbers, CIs, totals, grades, independence/safety certification or exercise, breathing, medication or treatment instructions.",
      "criterion": "Material for Separate funding, support, employed-author and interest materials must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.",
      "basis": "Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.",
      "condition_origin": "Internally applied conditions preserved for the existing subclaim. They do not establish preregistration, official-tool certification or completed content review.",
      "proposed_research": "Material needed: There is no material to fill this as no funding, independent support, no employed authors or no COI. This records needed materials; no new research was executed."
    },
    {
      "item_id": "N23",
      "question_type": "Evidence condition",
      "question": "Do 0 reported adverse events guarantee safety?",
      "needed": "Harm definitions, collection, arm exposure/denominators, discontinuation and missingness",
      "role": "Supplementary",
      "role_reason": "This condition connects Harm definitions, collection, arm exposure/denominators, discontinuation and missingness with selected 12-week resting systolic pressure, within- versus between-group comparisons, initial training versus maintenance, and measurement, denominator, support and harm boundaries.",
      "application_exception": "Preserve selected subclaim C and its within-group -12.9 mmHg note. Distinguish absent subclaim score/status/axes from parent grade C with 54 points. Within-group changes or a historical simple difference are not adjusted between-group effects; maintenance is not a minimum starting dose. Create no new numbers, CIs, totals, grades, independence/safety certification or exercise, breathing, medication or treatment instructions.",
      "criterion": "Material for Harm definitions, collection, arm exposure/denominators, discontinuation and missingness must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.",
      "basis": "Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.",
      "condition_origin": "Internally applied conditions preserved for the existing subclaim. They do not establish preregistration, official-tool certification or completed content review.",
      "proposed_research": "Material needed: Collection, arm exposure/denominators, severity, missingness, discontinuation and long-term harms are needed. Do not turn 0 into new safety certification. This records needed materials; no new research was executed."
    },
    {
      "item_id": "N24",
      "question_type": "Evidence condition",
      "question": "Are acute and longer-term resting pressure the same?",
      "needed": "Acute holds, resting results, bibliography, population and denominators",
      "role": "Supplementary",
      "role_reason": "This condition connects Acute holds, resting results, bibliography, population and denominators with selected 12-week resting systolic pressure, within- versus between-group comparisons, initial training versus maintenance, and measurement, denominator, support and harm boundaries.",
      "application_exception": "Preserve selected subclaim C and its within-group -12.9 mmHg note. Distinguish absent subclaim score/status/axes from parent grade C with 54 points. Within-group changes or a historical simple difference are not adjusted between-group effects; maintenance is not a minimum starting dose. Create no new numbers, CIs, totals, grades, independence/safety certification or exercise, breathing, medication or treatment instructions.",
      "criterion": "Material for Acute holds, resting results, bibliography, population and denominators must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.",
      "basis": "Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.",
      "condition_origin": "Internally applied conditions preserved for the existing subclaim. They do not establish preregistration, official-tool certification or completed content review.",
      "proposed_research": "Material needed: That acute study’s bibliography, population, denominators and measurement/exposure details are not linked. Do not borrow the other trials’ denominators or create a hypothetical report. This records needed materials; no new research was executed."
    },
    {
      "item_id": "N25",
      "question_type": "Evidence condition",
      "question": "Are long-term and vulnerable-population harms verified?",
      "needed": "Supervision, exposure, vulnerable populations, concurrent factors and long-term harms",
      "role": "Supplementary",
      "role_reason": "This condition connects Supervision, exposure, vulnerable populations, concurrent factors and long-term harms with selected 12-week resting systolic pressure, within- versus between-group comparisons, initial training versus maintenance, and measurement, denominator, support and harm boundaries.",
      "application_exception": "Preserve selected subclaim C and its within-group -12.9 mmHg note. Distinguish absent subclaim score/status/axes from parent grade C with 54 points. Within-group changes or a historical simple difference are not adjusted between-group effects; maintenance is not a minimum starting dose. Create no new numbers, CIs, totals, grades, independence/safety certification or exercise, breathing, medication or treatment instructions.",
      "criterion": "Material for Supervision, exposure, vulnerable populations, concurrent factors and long-term harms must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.",
      "basis": "Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.",
      "condition_origin": "Internally applied conditions preserved for the existing subclaim. They do not establish preregistration, official-tool certification or completed content review.",
      "proposed_research": "Material needed: Population/exposure-specific long-term harms, alternative causes and discontinuation materials are needed. Do not extend a small supervised sample into safety certification for other populations or unsupervised settings. This records needed materials; no new research was executed."
    },
    {
      "item_id": "N26",
      "question_type": "Evidence condition",
      "question": "How are original verdicts, dates and corrections preserved?",
      "needed": "Parent/subclaim grades, scores, axes, both languages, dates and absent values",
      "role": "Required",
      "role_reason": "This condition connects Parent/subclaim grades, scores, axes, both languages, dates and absent values with selected 12-week resting systolic pressure, within- versus between-group comparisons, initial training versus maintenance, and measurement, denominator, support and harm boundaries.",
      "application_exception": "Preserve selected subclaim C and its within-group -12.9 mmHg note. Distinguish absent subclaim score/status/axes from parent grade C with 54 points. Within-group changes or a historical simple difference are not adjusted between-group effects; maintenance is not a minimum starting dose. Create no new numbers, CIs, totals, grades, independence/safety certification or exercise, breathing, medication or treatment instructions.",
      "criterion": "Material for Parent/subclaim grades, scores, axes, both languages, dates and absent values must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.",
      "basis": "Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.",
      "condition_origin": "Internally applied conditions preserved for the existing subclaim. They do not establish preregistration, official-tool certification or completed content review.",
      "proposed_research": "Material needed: Historical key/sham, funding and acute-verification wording is not current review or clinical certification. Create no new grades, effects or hypothetical numbers. This records needed materials; no new research was executed."
    },
    {
      "item_id": "N27",
      "question_type": "Evidence condition",
      "question": "What material was actually read?",
      "needed": "Report/material links and paper, registration, plan and support states",
      "role": "Required",
      "role_reason": "This condition connects Report/material links and paper, registration, plan and support states with selected 12-week resting systolic pressure, within- versus between-group comparisons, initial training versus maintenance, and measurement, denominator, support and harm boundaries.",
      "application_exception": "Preserve selected subclaim C and its within-group -12.9 mmHg note. Distinguish absent subclaim score/status/axes from parent grade C with 54 points. Within-group changes or a historical simple difference are not adjusted between-group effects; maintenance is not a minimum starting dose. Create no new numbers, CIs, totals, grades, independence/safety certification or exercise, breathing, medication or treatment instructions.",
      "criterion": "Material for Report/material links and paper, registration, plan and support states must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.",
      "basis": "Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.",
      "condition_origin": "Internally applied conditions preserved for the existing subclaim. They do not establish preregistration, official-tool certification or completed content review.",
      "proposed_research": "Material needed: External papers, registration, protocols, SAPs, support and acute originals are unread; access was not attempted. Links or historical verification do not establish current reading. This records needed materials; no new research was executed."
    }
  ]
}