Multicomponent digital weight management × At least 5% weight loss

Required evidence, verification status and materials actually read
Item	AVerification status	BReading scope	CReview item	DCurrent findings	EWhy unverified	FRequired materials and conditions	GFurther research
1	Partly verified	Full text not readStored summary read	N01 · Evidence conditionSelected 5% claim and original gradeRequired	The selected subclaim is “At least 5% weight loss,” with grade C and a note of a secondary responder result of 40% versus 17%. Subclaim score/status/axes are absent; parent C56 is not used to fill the subclaim score. S01	Only the relevant information in the preserved summary is recorded; detailed originals remain unread and existing content review incomplete. Subclaim score, status and axes are absent. The primary mean endpoint and secondary responder endpoint are not combined. Existing content review remains incomplete.	Distinction between the original responder question/grade and the parent mean-weight verdict	A proposed follow-up comparison specifying the responder question and hierarchy; no new investigation, calculation or trial was performed.
2	Partly verified	Full text not readStored summary read	N02 · Evidence conditionDefinition of the 5% thresholdRequired	The original question concerns attaining the threshold of at least 5% weight loss. This is not converted into mean change in kg, individual final weight or change in every participant. S01	Only the relevant information in the preserved summary is recorded; detailed originals remain unread and existing content review incomplete. Reference weight/calculation formula, rounding/boundaries, evaluation windows, measurement selection and details of advance definitions remain unverified. Existing content review remains incomplete.	Threshold, reference weight, calculation/time point and responder-adjudication rules	A proposed follow-up study specifying thresholds, measurement and time points; no new investigation, calculation or trial was performed.
3	Partly verified	Full text not readStored summary read	N03 · Evidence condition40% versus 17% and P valueRequired	The original result was at least 5% weight loss in 40% versus 17%, P<0.001. No new proportion difference, RR/OR, NNT, CI or event count is calculated. S01	Only the relevant information in the preserved summary is recorded; detailed originals remain unread and existing content review incomplete. Analysis denominators/event counts for each proportion, exact test/model, CI and distinction between observed/estimated values remain unverified. Existing content review remains incomplete.	Distinction between original proportions, group correspondence, P value and new arithmetic	A proposed study reporting proportions together with uncertainty and denominators; no new investigation, calculation or trial was performed.
4	Partly verified	Full text not readStored summary read	N04 · Evidence conditionResponder denominators and event countsRequired	351 randomized participants (176/175) describe the original population. These are not multiplied by 40%/17% to create event counts or used to fill the effective denominator of each proportion. S01	Only the relevant information in the preserved summary is recorded; detailed originals remain unread and existing content review incomplete. Effective denominators for each proportion, responder counts, inclusion/exclusion and measured/estimated criteria remain unverified. Existing content review remains incomplete.	Randomized, observed and model denominators and actual responder counts	A proposed study reporting enrolled, observed and estimated denominators separately; no new investigation, calculation or trial was performed.
5	Partly verified	Full text not readStored summary read	N05 · Evidence conditionProportion effects, CIs and precisionRequired	Original proportions and P value are preserved. Proportion differences, relative effects, CIs or individual success probabilities unlinked in the manuscript are not newly created. S01	Only the relevant information in the preserved summary is recorded; detailed originals remain unread and existing content review incomplete. Planned effect measures, exact estimates, CIs and importance/success criteria remain unverified. Existing content review remains incomplete.	Original proportions, prespecified effect measures, CIs and clinical importance	A proposed follow-up study disclosing effect measures and uncertainty; no new investigation, calculation or trial was performed.
6	Partly verified	Full text not readStored summary read	N06 · Evidence conditionMean change is a different endpointRequired	Mean change of −4.0 kg versus −0.1 kg and a between-group difference of −3.8 kg (95% CI −5.0 to −2.5), P<0.001, form a separate primary endpoint. The 5% proportions, event counts or individual weight loss are not calculated from these. S01	Only the relevant information in the preserved summary is recorded; detailed originals remain unread and existing content review incomplete. Individual baseline/change distributions and data linking mean and responder outcomes remain unverified. Existing content review remains incomplete.	Distinction between continuous means and threshold-attainment distributions/proportions	A proposed follow-up trial distinguishing mean and responder endpoints; no new investigation, calculation or trial was performed.
7	Partly verified	Full text not readStored summary read	N07 · Evidence conditionSecondary endpoint and prespecified hierarchyRequired	The manuscript identifies at least 5% weight loss as a secondary responder result. This is not upgraded into a new primary endpoint, independent confirmatory trial or prespecified success threshold. S01	Only the relevant information in the preserved summary is recorded; detailed originals remain unread and existing content review incomplete. Pre-recruitment specification of responder definitions/analyses, test order, change history and estimation models remain unverified. Existing content review remains incomplete.	Distinction between the primary mean endpoint and secondary 5% responder result	A proposed study distinguishing the primary endpoint from prespecified responder analyses; no new investigation, calculation or trial was performed.
8	Partly verified	Full text not readStored summary read	N08 · Evidence conditionMeasured weight and responder-adjudication valuesRequired	Primary weight change used standardized measurement at research visits. This is distinguished from daily smart-scale/app entries and self-report; actual values/visit rules used for the 5% proportions are not filled in. S01	Only the relevant information in the preserved summary is recorded; detailed originals remain unread and existing content review incomplete. Measurement sources, evaluation windows, equipment/conditions and valid baseline/final values for responder adjudication remain unverified. Existing content review remains incomplete.	Correspondence between visit weight, self-monitoring/self-report and proportion calculations	A proposed study linking measured/remote measurements with responder calculations; no new investigation, calculation or trial was performed.
9	Partly verified	Full text not readStored summary read	N09 · Evidence conditionPopulation, comorbidities and recruitmentRequired	351 people aged 21–65 at community health centers had obesity and at least one of hypertension, diabetes or hyperlipidemia. This is not extended into the probability of attaining 5% loss in other populations. S01	Only the relevant information in the preserved summary is recorded; detailed originals remain unread and existing content review incomplete. Detailed eligibility, baseline weight/condition distributions, recruitment/exclusions and group balance remain unverified. Existing content review remains incomplete.	Obese population aged 21–65 with baseline conditions and applicability scope	A proposed follow-up study specifying applicability by population; no new investigation, calculation or trial was performed.
10	Partly verified	Full text not readStored summary read	N10 · Evidence conditionAttribution within multicomponent TrackRequired	The intervention bundled an app, cellular smart scale, 18 dietitian calls and clinician counseling. The proportion attaining 5% loss is not converted into an effect of a stand-alone app or a specific component. S01	Only the relevant information in the preserved summary is recorded; detailed originals remain unread and existing content review incomplete. Independent component effects, component-separation/combination designs and contributions of actual use remain unverified. Existing content review remains incomplete.	The full bundle versus individual effects of app/counseling and other components	A proposed follow-up comparison distinguishing bundle and component attribution; no new investigation, calculation or trial was performed.
11	Partly verified	Full text not readStored summary read	N11 · Evidence conditionComponent plans and actual useRequired	The manuscript records app self-monitoring/tailored feedback, daily cellular-scale weighing, 18 calls and counseling based on electronic-record recommendations. Plans are not used to imply actual completion by every participant. S01	Only the relevant information in the preserved summary is recorded; detailed originals remain unread and existing content review incomplete. Component-specific delivery/usage, adherence, discontinuation, contact intensity and differences in clinical/concurrent management remain unverified. Existing content review remains incomplete.	Delivery/exposure for app feedback, daily scale use, 18 calls and clinical integration	A proposed follow-up study distinguishing plans from actual exposure and response; no new investigation, calculation or trial was performed.
12	Partly verified	Full text not readStored summary read	N12 · Evidence conditionUsual-care controlRequired	The comparison involved 176 intervention participants versus 175 receiving usual care. Usual care is not described as no management/contact, and equal support in all respects is not established. S01	Only the relevant information in the preserved summary is recorded; detailed originals remain unread and existing content review incomplete. Control content, contact/support, additional programs, crossover use and baseline-condition management remain unverified. Existing content review remains incomplete.	Actual control management, contact and additional-exposure conditions	Proposed follow-up trial disclosing actual comparison conditions; no new investigation, calculation or trial was performed in this production.
13	Partly verified	Full text not readStored summary read	N13 · Evidence condition12-month assessment, maintenance and regainRequired	The responder result in the 12-month study context is preserved. Attaining the threshold once during follow-up, sustained attainment and maintenance/regain beyond 12 months are not made into the same outcome. S01	Only the relevant information in the preserved summary is recorded; detailed originals remain unread and existing content review incomplete. Exact evaluation windows, earlier responses, maintained attainment/regain and long-term/discontinuation follow-up remain unverified. Existing content review remains incomplete.	Distinction between the selected responder time point and persistence during or beyond follow-up	A proposed study reporting threshold attainment separately from maintenance/regain; no new investigation, calculation or trial was performed.
14	Partly verified	Full text not readStored summary read	N14 · Evidence conditionRandomization and allocation concealmentRequired	The manuscript records sequence generation by a statistician and concealment from study staff before allocation. It is not described as current original-source review or verification of allocation records. S01	Only the relevant information in the preserved summary is recorded; detailed originals remain unread and existing content review incomplete. Allocation records, implementation/exceptions, baseline balance and correspondence with the original protocol remain unread. Existing content review remains incomplete.	Historical allocation-procedure narrative and current access to originals	Proposed follow-up trial disclosing allocation procedures; no new investigation, calculation or trial was performed in this production.
15	Partly verified	Full text not readStored summary read	N15 · Evidence conditionAssessor masking and participant expectationsRequired	The manuscript records masked measurement staff and unmasked participants. This is not extended into verification of every responder-calculation/analysis role or exclusion of expectation effects. S01	Only the relevant information in the preserved summary is recorded; detailed originals remain unread and existing content review incomplete. Original materials on responder-adjudication/analysis roles, maintained masking and expectation/behavior effects remain unread. Existing content review remains incomplete.	Scope of masking for outcome assessors and participants	A proposed study distinguishing masking from participant behavior/expectation scope; no new investigation, calculation or trial was performed.
16	Partly verified	Full text not readStored summary read	N16 · Evidence conditionITT and responder-analysis populationRequired	The manuscript’s statement of following ITT is preserved. It is not automatically transferred into details of populations/handling used for the 5% proportions or verification of observation of all participants. S01	Only the relevant information in the preserved summary is recorded; detailed originals remain unread and existing content review incomplete. Responder-analysis inclusion/exclusion, actual population definitions, primary/sensitivity analyses and PPS correspondence remain unverified. Existing content review remains incomplete.	Overall ITT principle versus actual denominators/populations for secondary proportions	A proposed study separately disclosing analysis populations for continuous and responder outcomes; no new investigation, calculation or trial was performed.
17	Partly verified	Full text not readStored summary read	N17 · Evidence conditionMaximum-likelihood missing data and proportion handlingRequired	The manuscript’s prespecified-model maximum-likelihood estimation is preserved. This is not used as identical verification of missing-data handling or denominator rules for responder proportions. S01	Only the relevant information in the preserved summary is recorded; detailed originals remain unread and existing content review incomplete. Missing-data adjudication, imputation/estimation, nonresponse handling and model/sensitivity for the 5% result remain unverified. Existing content review remains incomplete.	Distinction between primary-analysis missing-data estimation and handling of unobserved responders	A proposed study reporting endpoint-specific missing-data handling and effects separately; no new investigation, calculation or trial was performed.
18	Unverified	Full text not readStored summary read	N18 · Evidence conditionAttrition, non-observation and missed visitsRequired	351 participants and 176/175 describe the randomized population. Without distinguishing observed/unobserved measurements and participant attrition, these are not used as outcomes for everyone or absence of missing-data effects. S01	Information currently needed is unverified in the preserved summary. Visit/group-specific observed counts, attrition causes, response-related missingness and follow-up status remain unverified. Existing content review remains incomplete.	Group-specific timing, causes and response effects of attrition/missingness	A proposed follow-up study disclosing effects of non-observation and response adjudication; no new investigation, calculation or trial was performed.
19	Partly verified	Full text not readStored summary read	N19 · Evidence conditionProportion tests, within/between groups and adjustmentRequired	The group correspondence of 40% versus 17% and P<0.001 is preserved as recorded. Within-group changes or rounded proportions are not converted into new adjusted effects or event risk ratios. S01	Only the relevant information in the preserved summary is recorded; detailed originals remain unread and existing content review incomplete. Exact tests, models/covariates, observed/estimated proportions, adjustment/advance plans and CIs remain unverified. Existing content review remains incomplete.	Proportion contrasts and original model, test and adjustment conditions	A proposed study clearly reporting proportion estimands and tests; no new investigation, calculation or trial was performed.
20	Partly verified	Full text not readStored summary read	N20 · Evidence conditionRegistration and advance responder plansRequired	Original NCT01827800, posting on 2013-04-10 and allocation starting on 2013-06-18 are preserved. Prospective registration and agreement with the primary 12-month mean endpoint do not substitute for verification of all 5% analysis conditions. S01	Only the relevant information in the preserved summary is recorded; detailed originals remain unread and existing content review incomplete. Secondary responder plans/definitions, pre-recruitment SAP, change history and full registration remain unread. Existing content review remains incomplete.	NCT identifier and scope of advance plans for primary/secondary proportion endpoints	A proposed study openly linking registration with actual secondary analyses; no new investigation, calculation or trial was performed.
21	Partly verified	Full text not readStored summary read	N21 · Evidence conditionMultiple outcomes, hierarchy and time pointsRequired	5% is a secondary outcome distinct from mean weight. Success at multiple time points, blood-pressure/glucose/other outcomes or independent replication is not newly created. S01	Only the relevant information in the preserved summary is recorded; detailed originals remain unread and existing content review incomplete. Complete lists of secondary outcomes/time points, adjustment, hierarchy and analysis/reporting changes remain unverified. Existing content review remains incomplete.	Multiplicity in testing responders and other time points/endpoints	A proposed study separating primary endpoints from secondary proportions and other outcomes; no new investigation, calculation or trial was performed.
22	Partly verified	Full text not readStored summary read	N22 · Evidence conditionThresholds, importance and disease eventsRequired	The manuscript records no declared prespecified success threshold or externally validated minimum clinically important difference. The secondary 5% threshold is not repurposed as a trial-success boundary or reductions in blood pressure/glucose/disease events. S01	Only the relevant information in the preserved summary is recorded; detailed originals remain unread and existing content review incomplete. Evidence for threshold importance, advance success definitions and patient-important clinical/long-term outcomes remain unverified. Existing content review remains incomplete.	Distinction between 5% response, advance success/importance criteria and clinical outcomes	A proposed follow-up study distinguishing responders from clinical outcomes; no new investigation, calculation or trial was performed.
23	Unverified	Full text not readStored summary read	N23 · Evidence conditionConcurrent management, medication and lifestyleRequired	This bundled trial involved baseline conditions and clinician counseling. Absence of medication/diet/activity/contact differences or effects on attaining 5% loss is not assumed. S01	Information currently needed is unverified in the preserved summary. Group-specific concurrent management/medication changes, lifestyle, additional support and their analyses remain unverified. Existing content review remains incomplete.	Concurrent conditions/medication, lifestyle/clinical exposure and responder outcomes	A proposed follow-up study distinguishing concurrent management from responder outcomes; no new investigation, calculation or trial was performed.
24	Partly verified	Full text not readStored summary read	N24 · Evidence conditionNIH public supportRequired	NIH NIDDK R01DK093829 provided support. This is not used as absence of all commercial/author relationships or new independence certification. S01	Only the relevant information in the preserved summary is recorded; detailed originals remain unread and existing content review incomplete. Funder/researcher roles, agreements, data/publication rights and complete disclosures remain unread. Existing content review remains incomplete.	Distinction between funder/grant, support roles and independence	Proposed follow-up trial disclosing support/research roles; no new investigation, calculation or trial was performed in this production.
25	Partly verified	Full text not readStored summary read	N25 · Evidence conditionNon-reporting of support in the pivotal paperRequired	The manuscript states that commercial sponsorship, donated scales, outsourced analysis, medical writing and publication-fee support were not reported in the pivotal paper. Non-reporting is not judged as actual absence of support. S01	Only the relevant information in the preserved summary is recorded; detailed originals remain unread and existing content review incomplete. Actual presence/scope of each support category, agreements, analysis/writing roles and original disclosures remain unread. Existing content review remains incomplete.	Category-specific scope of commercial, in-kind, outsourced-analysis/writing and publication support	A proposed study disclosing support categories distinctly; no new investigation, calculation or trial was performed.
26	Partly verified	Full text not readStored summary read	N26 · Evidence conditionLater author relationships and disclosure timingRequired	The original record places later-paper disclosures of Gary Bennett’s WW advisory role and equity in Coeus Health after the pivotal trial. Funding/COI during that trial are not retrospectively established. S01	Only the relevant information in the preserved summary is recorded; detailed originals remain unread and existing content review incomplete. Specific later bibliography, disclosure timing, relationships/agreements during the original trial and complete COI remain unlinked/unread. Existing content review remains incomplete.	Distinction between later WW/Coeus disclosures and original-trial timing/roles	A proposed study distinguishing relationship/support attribution by period; no new investigation, calculation or trial was performed.
27	Partly verified	Full text not readStored summary read	N27 · Evidence conditionReferences to null results from other programsRequired	References to null trials of app-only or low-intensity technology support limit generalization because composition/intensity differ. Those reports are not newly created or combined as direct refutations or independent replications of Track’s responder result. S01	Only the relevant information in the preserved summary is recorded; detailed originals remain unread and existing content review incomplete. Specific bibliography, populations, proportions/endpoints, denominators and results for other programs remain unlinked. Existing content review remains incomplete.	Directness of Track’s bundle versus app-only/low-intensity programs	A proposed direct follow-up comparison matching composition and intensity; no new investigation, calculation or trial was performed.
28	Partly verified	Full text not readStored summary read	N28 · Evidence conditionSame report, sibling sheets and independenceRequired	The 5% and mean sheets share the same Bennett2018 Track trial of 351 participants. Groups, time points, thresholds, bibliography/registration and sibling sheets are not added as new independent trials or participants. S01	Only the relevant information in the preserved summary is recorded; detailed originals remain unread and existing content review incomplete. Independent reproduction under the same bundle/responder conditions and unique clinical totals are not established. Existing content review remains incomplete.	Mean/responder, report/registration and group/time-point relationships	A proposed independent follow-up comparison specifying the same secondary threshold; no new investigation, calculation or trial was performed.
29	Partly verified	Full text not readStored summary read	N29 · Evidence conditionPersistence and applicability to other compositions/populationsRequired	The 12-month bundled trial’s responder result is not extended to all apps/products, other populations, maintenance after stopping the intervention or disease treatment. No new recommendations or weight-loss instructions are created. S01	Only the relevant information in the preserved summary is recorded; detailed originals remain unread and existing content review incomplete. Long-term/discontinuation follow-up, other compositions/populations and direct single-component comparisons remain unverified. Existing content review remains incomplete.	Distinction between Track responder results and long-term/stand-alone-app/other-population effects	A proposed study distinguishing threshold attainment from persistence/applicability; no new investigation, calculation or trial was performed.
30	Partly verified	Full text not readStored summary read	N30 · Harm-information gaps supplementing the efficacy tableUnknown safety and collection gapsSupplementary	The original record states that parent safety is unknown and adverse events from a prespecified safety endpoint were not systematically presented in the pivotal paper. Attaining 5% loss is not converted into absence of harm or treatment safety. S01	Only the relevant information in the preserved summary is recorded; detailed originals remain unread and existing content review incomplete. Adverse-event collection/adjudication, group-specific types/frequencies/denominators, discontinuation and vulnerable-population/long-term harms remain unverified. Existing content review remains incomplete.	Prespecification, collection/denominators and follow-up for adverse events	A proposed follow-up study specifying harm collection and follow-up; no new investigation, calculation or trial was performed.
31	Partly verified	Full text not readStored summary read	N31 · Evidence conditionParent/subclaim, Korean/English, corrections and historyRequired	Parent C56, B/S/R1/I2/E+/B0, unrecorded precision, three false flags, empty override reasons and subclaim grade C/note are preserved. Korean/English text, 2026-08-26, empty corrections/deliberation and historical cross-checking are not inherited as current review or a subclaim score. S01	Only the relevant information in the preserved summary is recorded; detailed originals remain unread and existing content review incomplete. Absent subclaim score/status/axes are not filled with parent values, and no new certification is created. Existing content review remains incomplete.	Separate preservation of original values/axes, reference dates and verification narratives	Proposed research distinguishing original values/history from new-update scope; no new investigation, calculation or trial was performed in this production.
32	Partly verified	Full text not readStored summary read	N32 · Evidence conditionSummary reading, external links and updatesRequired	The full preserved JSON summary and bibliography were used for production, and links are retained. Papers, registration, protocol, SAP and original later disclosures/support materials remain unread with no access attempt; links were not tested. S01	Only the relevant information in the preserved summary is recorded; detailed originals remain unread and existing content review incomplete. External originals, exact responder denominators/models and actual accessibility remain unverified. Existing content review remains incomplete.	Actually read scope and access status of external materials	A proposed study updating acquisition, timing and scope of materials separately; no new investigation, calculation or trial was performed.

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32 itemsWhat the statuses mean

Assessment scope

Stored-material review date: Not recorded
Original evidence cut-off: 2026-08-26
Scope actually checked: Existing review summaries and stored records of methodological application. Full papers, supplements, registrations, plans and original data were not read.
What the dates mean: This is the date the stored materials were checked, not the date of a new search of the clinical literature.
Population: 351 adults aged 21–65 with obesity at US community health centers, with at least one of hypertension, diabetes or hyperlipidemia. Original randomized denominators: 176 intervention/175 usual care. Detailed eligibility, baseline weight/conditions, visit-specific observations/analyses and attrition/missingness remain unverified.
Ingredient, formulation and route: Multicomponent Track: app-based goal self-monitoring, algorithm-tailored feedback, daily cellular smart-scale weighing, 18 dietitian calls and clinician counseling based on electronic-record recommendations. Stand-alone app/scale/counseling effects cannot be separated. Only the research composition is preserved; no implementation instructions or recommendations are created.
Dose: Only original planned elements such as 18 counseling calls and daily self-monitoring, and the 12-month evaluation, are preserved. Actual component-specific delivery/use, cumulative contacts, adherence and discontinuation remain unverified; completion by all participants is not assumed.
Comparator: Parallel comparison with usual care. Actual control management, contact/support, use of other programs, concurrent medication/condition/lifestyle management and crossover use remain unverified. Usual care is not converted into no intervention or contact.
Measured outcome: At least 5% weight loss in 40% versus 17%, P<0.001, is a secondary responder result. Reference values/measurements for threshold calculation, exact denominators/events, proportion models, CIs and missing-data handling remain unverified. Attainment rates or event counts are not calculated from primary mean change or the between-group difference, and 5% is not upgraded into a prespecified success threshold or reduced clinical events.
Duration: Study context for 12-month weight/responder outcomes. Visit windows, changes by time point, continuation/discontinuation beyond 12 months and long-term clinical/harm follow-up remain unverified.
Questions outside this scope: Newly subtracting group-specific −4.0/−0.1 kg to recalculate the original between-group difference of −3.8 kg and CI; Calculating 5% attainment rates, responder events/denominators or individual outcomes from continuous mean change; Applying 176/175 to 40%/17% to calculate event counts or new differences/RR/OR/NNT/CIs; Automatically substituting daily smart-scale/app entries for standardized visit measurements or actual adjudication values for secondary proportions; Repurposing general ITT/prespecified maximum-likelihood narratives as complete verification of responder missingness/denominator rules; Upgrading the secondary 5% endpoint into a primary endpoint, prespecified success threshold, validated minimum clinically important difference or reductions in blood pressure/glucose/disease events; Repurposing the app/smart-scale/counseling bundle result as effects of a stand-alone app, individual components or all products/populations; Using 351 participants, 176/175, groups, time points, components, bibliography/registration or sibling sheets as new independent trial/participant totals; Judging non-reporting of pivotal-trial support as actual absence, or retrospectively confirming later WW/Coeus disclosures as original-trial relationships; Creating unlinked low-intensity null trials or later disclosures as new reports, direct refutations or independent replications; Inheriting original parent values, axes and historical verification as a subclaim score or current content review/registration/original-source reading; New calculations, invented quantities, effects/CIs, grades, independence certification, app/product recommendations or weight/diet/exercise/weight-loss/treatment-replacement instructions

Evidence and sources

The links below lead to the sources. A link alone does not mean the original source was read or its latest publication status verified.

S01 · Bennett GG et al. 2018 Track

PubMed

Material type: Community-health-center randomized usual-care-controlled effectiveness trial
Materials actually read: Summary read; external material unread
Findings recorded in the stored summary: −4.0 kg versus −0.1 kg; between-group difference −3.8 kg (95% CI −5.0 to −2.5), P<0.001. At least 5% weight loss was 40% versus 17%, P<0.001, but this was a secondary responder criterion rather than the primary endpoint. Null trials of app-only or low-intensity technology support are also noted; this result is limited to the Track bundle including counseling.
Record level: Outcome wording in the stored summary
Study overlap and independent replication: S01 Bennett2018 Track is one 12-month parallel report comparing bundled Track with usual care in 351 adults (176/175) aged 21–65 with obesity and at least one of hypertension/diabetes/hyperlipidemia at US community health centers. Individual effects of the app, cellular smart scale, 18 dietitian calls and clinician counseling cannot be separated. The two sheets share the same people/report. Standardized research-visit mean changes of −4.0 kg (95% CI −4.9 to −3.0) versus −0.1 kg (−1.0 to 0.8), and between-group difference −3.8 kg (−5.0 to −2.5), P<0.001, are primary continuous results. At least 5% weight loss, 40% versus 17%, P<0.001, is a secondary responder result; proportions or event counts are not calculated from means. Registration, ITT/maximum likelihood, public funding and later author disclosures are preserved historical narratives, not current external reading/content review. Specific bibliographies for other low-intensity null trials and later disclosures are unlinked, so no new report is created. Groups, time points, thresholds, bibliography/registration and sibling sheets are not added as new independent trials or participants; report-item counts are not unique clinical totals.

Public availability, access and reading status by material
Material	Public availability	Access status	Actually read	Notes
Stored summary	Stored file	Stored summary	Summary read	Only stored-summary and bibliographic content was used for production. External material verification/review is not complete.
External paper	Public availability unverified; only bibliography links preserved	Unread; access not attempted	Not read	No external access or click testing was performed in the original preparation. URLs or registration identifiers alone do not upgrade acquisition/reading status.
Registration material	Public availability unverified; only bibliography links preserved	Unread; access not attempted	Not read	No external access or click testing was performed in the original preparation. URLs or registration identifiers alone do not upgrade acquisition/reading status.
Protocol	Public availability unverified; only bibliography links preserved	Unread; access not attempted	Not read	No external access or click testing was performed in the original preparation. URLs or registration identifiers alone do not upgrade acquisition/reading status.
Statistical analysis plan	Public availability unverified; only bibliography links preserved	Unread; access not attempted	Not read	No external access or click testing was performed in the original preparation. URLs or registration identifiers alone do not upgrade acquisition/reading status.
Funding, product-support and COI material	Public availability unverified; only bibliography links preserved	Unread; access not attempted	Not read	No external access or click testing was performed in the original preparation. URLs or registration identifiers alone do not upgrade acquisition/reading status.

Report counts versus independent study counts

S01 Bennett2018 Track is one 12-month parallel report comparing bundled Track with usual care in 351 adults (176/175) aged 21–65 with obesity and at least one of hypertension/diabetes/hyperlipidemia at US community health centers. Individual effects of the app, cellular smart scale, 18 dietitian calls and clinician counseling cannot be separated. The two sheets share the same people/report. Standardized research-visit mean changes of −4.0 kg (95% CI −4.9 to −3.0) versus −0.1 kg (−1.0 to 0.8), and between-group difference −3.8 kg (−5.0 to −2.5), P<0.001, are primary continuous results. At least 5% weight loss, 40% versus 17%, P<0.001, is a secondary responder result; proportions or event counts are not calculated from means. Registration, ITT/maximum likelihood, public funding and later author disclosures are preserved historical narratives, not current external reading/content review. Specific bibliographies for other low-intensity null trials and later disclosures are unlinked, so no new report is created. Groups, time points, thresholds, bibliography/registration and sibling sheets are not added as new independent trials or participants; report-item counts are not unique clinical totals.

Review criteria

Version 1.0 · Criteria record date 2026-10-06. These are Chamgap's own application conditions, informed by the referenced methods. They do not constitute official assessment-tool certification or a new efficacy score.

N01 · Selected 5% claim and original grade

Required materials and conditions: Distinction between the original responder question/grade and the parent mean-weight verdict
Conditions for verification: Corresponding original materials and analysis scope for distinction between the original responder question/grade and the parent mean-weight verdict must be available and unverified matters distinguishable. Preserved wording is linked here; existing content review remains incomplete.
Requirement and applicability: Required
Application exceptions: Limited to the preserved summary’s selected strategy/population/endpoint/period. It does not replace numbers for other strategies/trials/endpoints or unread external materials.
Why this condition is needed: An applied item distinguishing distinction between the original responder question/grade and the parent mean-weight verdict to connect the selected question’s needed materials with current materials.
Referenced methods: M03 §3.1, §3.2.1–3.2.4 question-clarification principles; detailed separation rules are custom design; M03 §3.2.4, M15 §15.3.1–15.3.3; question-specific outcome adaptation is custom design; M04 §4.5, §4.6.3; limits on current material conversion reflect the review scope and custom design

N02 · Definition of the 5% threshold

Required materials and conditions: Threshold, reference weight, calculation/time point and responder-adjudication rules
Conditions for verification: Corresponding original materials and analysis scope for threshold, reference weight, calculation/time point and responder-adjudication rules must be available and unverified matters distinguishable. Preserved wording is linked here; existing content review remains incomplete.
Requirement and applicability: Required
Application exceptions: Limited to the preserved summary’s selected strategy/population/endpoint/period. It does not replace numbers for other strategies/trials/endpoints or unread external materials.
Why this condition is needed: An applied item distinguishing threshold, reference weight, calculation/time point and responder-adjudication rules to connect the selected question’s needed materials with current materials.
Referenced methods: M03 §3.2.4, M15 §15.3.1–15.3.3; question-specific outcome adaptation is custom design; M08 §8.2.2, M15 §15.3.1; custom application; M08 Table 8.2.a, M04 §4.6.3; custom application

N03 · 40% versus 17% and P value

Required materials and conditions: Distinction between original proportions, group correspondence, P value and new arithmetic
Conditions for verification: Corresponding original materials and analysis scope for distinction between original proportions, group correspondence, P value and new arithmetic must be available and unverified matters distinguishable. Preserved wording is linked here; existing content review remains incomplete.
Requirement and applicability: Required
Application exceptions: Limited to the preserved summary’s selected strategy/population/endpoint/period. It does not replace numbers for other strategies/trials/endpoints or unread external materials.
Why this condition is needed: An applied item distinguishing distinction between original proportions, group correspondence, P value and new arithmetic to connect the selected question’s needed materials with current materials.
Referenced methods: M15 §15.3.1–15.3.3; CHAMGAP adaptation; M08 Table 8.2.a, M15 §15.3, M19 §19.1.2–19.2.4; Design-specific adaptations are designed by CHAMGAP; M08 §8.2.2, M15 §15.3.1; CHAMGAP adaptation

N04 · Responder denominators and event counts

Required materials and conditions: Randomized, observed and model denominators and actual responder counts
Conditions for verification: Corresponding original materials and analysis scope for randomized, observed and model denominators and actual responder counts must be available and unverified matters distinguishable. Preserved wording is linked here; existing content review remains incomplete.
Requirement and applicability: Required
Application exceptions: Limited to the preserved summary’s selected strategy/population/endpoint/period. It does not replace numbers for other strategies/trials/endpoints or unread external materials.
Why this condition is needed: An applied item distinguishing randomized, observed and model denominators and actual responder counts to connect the selected question’s needed materials with current materials.
Referenced methods: M08 Table 8.2.a, M15 §15.3 and M19 §19.1.2–19.2.4; Design-specific adaptation is Chamgap design; M08 §8.2.2 and M15 §15.3.1; Chamgap application

N05 · Proportion effects, CIs and precision

Required materials and conditions: Original proportions, prespecified effect measures, CIs and clinical importance
Conditions for verification: Corresponding original materials and analysis scope for original proportions, prespecified effect measures, CIs and clinical importance must be available and unverified matters distinguishable. Preserved wording is linked here; existing content review remains incomplete.
Requirement and applicability: Required
Application exceptions: Limited to the preserved summary’s selected strategy/population/endpoint/period. It does not replace numbers for other strategies/trials/endpoints or unread external materials.
Why this condition is needed: An applied item distinguishing original proportions, prespecified effect measures, CIs and clinical importance to connect the selected question’s needed materials with current materials.
Referenced methods: M15 §15.3.1–15.3.3; custom application; M08 Table 8.2.a, M15 §15.3, M19 §19.1.2–19.2.4; design-specific adaptation is custom design; M08 Table 8.2.a, M04 §4.6.3; custom application

N06 · Mean change is a different endpoint

Required materials and conditions: Distinction between continuous means and threshold-attainment distributions/proportions
Conditions for verification: Corresponding original materials and analysis scope for distinction between continuous means and threshold-attainment distributions/proportions must be available and unverified matters distinguishable. Preserved wording is linked here; existing content review remains incomplete.
Requirement and applicability: Required
Application exceptions: Limited to the preserved summary’s selected strategy/population/endpoint/period. It does not replace numbers for other strategies/trials/endpoints or unread external materials.
Why this condition is needed: An applied item distinguishing distinction between continuous means and threshold-attainment distributions/proportions to connect the selected question’s needed materials with current materials.
Referenced methods: M03 §3.2.4, M15 §15.3.1–15.3.3; question-specific outcome adaptations are Chamgap's own design; M08 §8.2.2, M15 §15.3.1; Chamgap's own application; M15 §15.3.1–15.3.3; Chamgap's own application

N07 · Secondary endpoint and prespecified hierarchy

Required materials and conditions: Distinction between the primary mean endpoint and secondary 5% responder result
Conditions for verification: Corresponding original materials and analysis scope for distinction between the primary mean endpoint and secondary 5% responder result must be available and unverified matters distinguishable. Preserved wording is linked here; existing content review remains incomplete.
Requirement and applicability: Required
Application exceptions: Limited to the preserved summary’s selected strategy/population/endpoint/period. It does not replace numbers for other strategies/trials/endpoints or unread external materials.
Why this condition is needed: An applied item distinguishing distinction between the primary mean endpoint and secondary 5% responder result to connect the selected question’s needed materials with current materials.
Referenced methods: M08 Table 8.2.a, M04 §4.6.3; internal application; M04 §4.6.3, M15 §15.3.1–15.3.3; status separation is internally designed; M04 §4.6.1–4.6.2 distinguishes studies from reports; cohort/outcome links are an internal application

N08 · Measured weight and responder-adjudication values

Required materials and conditions: Correspondence between visit weight, self-monitoring/self-report and proportion calculations
Conditions for verification: Corresponding original materials and analysis scope for correspondence between visit weight, self-monitoring/self-report and proportion calculations must be available and unverified matters distinguishable. Preserved wording is linked here; existing content review remains incomplete.
Requirement and applicability: Required
Application exceptions: Limited to the preserved summary’s selected strategy/population/endpoint/period. It does not replace numbers for other strategies/trials/endpoints or unread external materials.
Why this condition is needed: An applied item distinguishing correspondence between visit weight, self-monitoring/self-report and proportion calculations to connect the selected question’s needed materials with current materials.
Referenced methods: M03 §3.2.4, M15 §15.3.1–15.3.3; question-specific outcome adaptations are internally designed; M08 Table 8.2.a, M03 §3.2.4; internal application; M08 §8.2.2, M15 §15.3.1; internal application

N09 · Population, comorbidities and recruitment

Required materials and conditions: Obese population aged 21–65 with baseline conditions and applicability scope
Conditions for verification: Corresponding original materials and analysis scope for obese population aged 21–65 with baseline conditions and applicability scope must be available and unverified matters distinguishable. Preserved wording is linked here; existing content review remains incomplete.
Requirement and applicability: Required
Application exceptions: Limited to the preserved summary’s selected strategy/population/endpoint/period. It does not replace numbers for other strategies/trials/endpoints or unread external materials.
Why this condition is needed: An applied item distinguishing obese population aged 21–65 with baseline conditions and applicability scope to connect the selected question’s needed materials with current materials.
Referenced methods: M03 §3.2.1; Detailed population conditions are Chamgap design; M03 §3.2.1–3.2.4; Dose, duration and effect-modifier details are Chamgap design

N10 · Attribution within multicomponent Track

Required materials and conditions: The full bundle versus individual effects of app/counseling and other components
Conditions for verification: Corresponding original materials and analysis scope for the full bundle versus individual effects of app/counseling and other components must be available and unverified matters distinguishable. Preserved wording is linked here; existing content review remains incomplete.
Requirement and applicability: Required
Application exceptions: Limited to the preserved summary’s selected strategy/population/endpoint/period. It does not replace numbers for other strategies/trials/endpoints or unread external materials.
Why this condition is needed: An applied item distinguishing the full bundle versus individual effects of app/counseling and other components to connect the selected question’s needed materials with current materials.
Referenced methods: M03 §3.2.2–3.2.3; Reverse-direction labels and assessment adaptation are Chamgap design; M03 §3.2.3 and M08 §8.2.2–8.2.3; Chamgap application

N11 · Component plans and actual use

Required materials and conditions: Delivery/exposure for app feedback, daily scale use, 18 calls and clinical integration
Conditions for verification: Corresponding original materials and analysis scope for delivery/exposure for app feedback, daily scale use, 18 calls and clinical integration must be available and unverified matters distinguishable. Preserved wording is linked here; existing content review remains incomplete.
Requirement and applicability: Required
Application exceptions: Limited to the preserved summary’s selected strategy/population/endpoint/period. It does not replace numbers for other strategies/trials/endpoints or unread external materials.
Why this condition is needed: An applied item distinguishing delivery/exposure for app feedback, daily scale use, 18 calls and clinical integration to connect the selected question’s needed materials with current materials.
Referenced methods: M03 §3.2.3, M08 §8.2.2–8.2.3; own application; M03 §3.2.2–3.2.3; reverse-direction labels and test adaptations are our own design

N12 · Usual-care control

Required materials and conditions: Actual control management, contact and additional-exposure conditions
Conditions for verification: Corresponding original materials and analysis scope for actual control management, contact and additional-exposure conditions must be available and unverified matters distinguishable. Preserved wording is linked here; existing content review remains incomplete.
Requirement and applicability: Required
Application exceptions: Limited to the preserved summary’s selected strategy/population/endpoint/period. It does not replace numbers for other strategies/trials/endpoints or unread external materials.
Why this condition is needed: An applied item distinguishing actual control management, contact and additional-exposure conditions to connect the selected question’s needed materials with current materials.
Referenced methods: M03 §3.2.2–3.2.3; Reverse-direction labels and assessment adaptation are Chamgap design; M03 §3.2.3 and M08 §8.2.2–8.2.3; Chamgap application

N13 · 12-month assessment, maintenance and regain

Required materials and conditions: Distinction between the selected responder time point and persistence during or beyond follow-up
Conditions for verification: Corresponding original materials and analysis scope for distinction between the selected responder time point and persistence during or beyond follow-up must be available and unverified matters distinguishable. Preserved wording is linked here; existing content review remains incomplete.
Requirement and applicability: Required
Application exceptions: Limited to the preserved summary’s selected strategy/population/endpoint/period. It does not replace numbers for other strategies/trials/endpoints or unread external materials.
Why this condition is needed: An applied item distinguishing distinction between the selected responder time point and persistence during or beyond follow-up to connect the selected question’s needed materials with current materials.
Referenced methods: M03 §3.2.4, M15 §15.3.1–15.3.3; question-specific outcome adaptations are internally designed; M03 §3.2.1–3.2.4; dose, duration and effect-modification details are internally designed

N14 · Randomization and allocation concealment

Required materials and conditions: Historical allocation-procedure narrative and current access to originals
Conditions for verification: Corresponding original materials and analysis scope for historical allocation-procedure narrative and current access to originals must be available and unverified matters distinguishable. Preserved wording is linked here; existing content review remains incomplete.
Requirement and applicability: Required
Application exceptions: Limited to the preserved summary’s selected strategy/population/endpoint/period. It does not replace numbers for other strategies/trials/endpoints or unread external materials.
Why this condition is needed: An applied item distinguishing historical allocation-procedure narrative and current access to originals to connect the selected question’s needed materials with current materials.
Referenced methods: M08 §8.1–8.2.3; internal application; M04 §4.5–4.6 collection/selection principles; access/reading separation and hyperlink specifications are internally designed

N15 · Assessor masking and participant expectations

Required materials and conditions: Scope of masking for outcome assessors and participants
Conditions for verification: Corresponding original materials and analysis scope for scope of masking for outcome assessors and participants must be available and unverified matters distinguishable. Preserved wording is linked here; existing content review remains incomplete.
Requirement and applicability: Required
Application exceptions: Limited to the preserved summary’s selected strategy/population/endpoint/period. It does not replace numbers for other strategies/trials/endpoints or unread external materials.
Why this condition is needed: An applied item distinguishing scope of masking for outcome assessors and participants to connect the selected question’s needed materials with current materials.
Referenced methods: M08 Table 8.2.a, M03 §3.2.4; CHAMGAP adaptation; Material collection/selection principles in M04 §4.5–4.6; Separating access from reading and defining hyperlink behavior are designed by CHAMGAP

N16 · ITT and responder-analysis population

Required materials and conditions: Overall ITT principle versus actual denominators/populations for secondary proportions
Conditions for verification: Corresponding original materials and analysis scope for overall ITT principle versus actual denominators/populations for secondary proportions must be available and unverified matters distinguishable. Preserved wording is linked here; existing content review remains incomplete.
Requirement and applicability: Required
Application exceptions: Limited to the preserved summary’s selected strategy/population/endpoint/period. It does not replace numbers for other strategies/trials/endpoints or unread external materials.
Why this condition is needed: An applied item distinguishing overall ITT principle versus actual denominators/populations for secondary proportions to connect the selected question’s needed materials with current materials.
Referenced methods: M08 §8.2.2 and M15 §15.3.1: in-house application; M08 Table 8.2.a, M15 §15.3 and M19 §19.1.2–19.2.4: design-specific adaptation is in-house.

N17 · Maximum-likelihood missing data and proportion handling

Required materials and conditions: Distinction between primary-analysis missing-data estimation and handling of unobserved responders
Conditions for verification: Corresponding original materials and analysis scope for distinction between primary-analysis missing-data estimation and handling of unobserved responders must be available and unverified matters distinguishable. Preserved wording is linked here; existing content review remains incomplete.
Requirement and applicability: Required
Application exceptions: Limited to the preserved summary’s selected strategy/population/endpoint/period. It does not replace numbers for other strategies/trials/endpoints or unread external materials.
Why this condition is needed: An applied item distinguishing distinction between primary-analysis missing-data estimation and handling of unobserved responders to connect the selected question’s needed materials with current materials.
Referenced methods: M08 Table 8.2.a, M15 §15.3 and M19 §19.1.2–19.2.4; Design-specific adaptation is Chamgap design; M08 §8.2.2 and M15 §15.3.1; Chamgap application

N18 · Attrition, non-observation and missed visits

Required materials and conditions: Group-specific timing, causes and response effects of attrition/missingness
Conditions for verification: Corresponding original materials and analysis scope for group-specific timing, causes and response effects of attrition/missingness must be available and unverified matters distinguishable. Preserved wording is linked here; existing content review remains incomplete.
Requirement and applicability: Required
Application exceptions: Limited to the preserved summary’s selected strategy/population/endpoint/period. It does not replace numbers for other strategies/trials/endpoints or unread external materials.
Why this condition is needed: An applied item distinguishing group-specific timing, causes and response effects of attrition/missingness to connect the selected question’s needed materials with current materials.
Referenced methods: M08 Table 8.2.a, M15 §15.3 and M19 §19.1.2–19.2.4; Design-specific adaptation is Chamgap design; M08 §8.2.2 and M15 §15.3.1; Chamgap application

N19 · Proportion tests, within/between groups and adjustment

Required materials and conditions: Proportion contrasts and original model, test and adjustment conditions
Conditions for verification: Corresponding original materials and analysis scope for proportion contrasts and original model, test and adjustment conditions must be available and unverified matters distinguishable. Preserved wording is linked here; existing content review remains incomplete.
Requirement and applicability: Required
Application exceptions: Limited to the preserved summary’s selected strategy/population/endpoint/period. It does not replace numbers for other strategies/trials/endpoints or unread external materials.
Why this condition is needed: An applied item distinguishing proportion contrasts and original model, test and adjustment conditions to connect the selected question’s needed materials with current materials.
Referenced methods: M08 §8.2.2, M15 §15.3.1; internal application; M15 §15.3.1–15.3.3; internal application; M08 Table 8.2.a, M04 §4.6.3; internal application

N20 · Registration and advance responder plans

Required materials and conditions: NCT identifier and scope of advance plans for primary/secondary proportion endpoints
Conditions for verification: Corresponding original materials and analysis scope for nCT identifier and scope of advance plans for primary/secondary proportion endpoints must be available and unverified matters distinguishable. Preserved wording is linked here; existing content review remains incomplete.
Requirement and applicability: Required
Application exceptions: Limited to the preserved summary’s selected strategy/population/endpoint/period. It does not replace numbers for other strategies/trials/endpoints or unread external materials.
Why this condition is needed: An applied item distinguishing nCT identifier and scope of advance plans for primary/secondary proportion endpoints to connect the selected question’s needed materials with current materials.
Referenced methods: M08 Table 8.2.a, M04 §4.6.3; custom application; M04 §4.5–4.6 material-collection/selection principles; separation of access/reading and hyperlink conventions are custom design; M04 §4.5, §4.6.3; limits on current material conversion reflect the review scope and custom design

N21 · Multiple outcomes, hierarchy and time points

Required materials and conditions: Multiplicity in testing responders and other time points/endpoints
Conditions for verification: Corresponding original materials and analysis scope for multiplicity in testing responders and other time points/endpoints must be available and unverified matters distinguishable. Preserved wording is linked here; existing content review remains incomplete.
Requirement and applicability: Required
Application exceptions: Limited to the preserved summary’s selected strategy/population/endpoint/period. It does not replace numbers for other strategies/trials/endpoints or unread external materials.
Why this condition is needed: An applied item distinguishing multiplicity in testing responders and other time points/endpoints to connect the selected question’s needed materials with current materials.
Referenced methods: M08 Table 8.2.a, M04 §4.6.3; own application; M04 §4.6.1–4.6.2 on distinguishing studies from reports; cohort/outcome linkage is independently applied; M03 §3.2.4, M15 §15.3.1–15.3.3; question-specific outcome adaptation is independently designed

N22 · Thresholds, importance and disease events

Required materials and conditions: Distinction between 5% response, advance success/importance criteria and clinical outcomes
Conditions for verification: Corresponding original materials and analysis scope for distinction between 5% response, advance success/importance criteria and clinical outcomes must be available and unverified matters distinguishable. Preserved wording is linked here; existing content review remains incomplete.
Requirement and applicability: Required
Application exceptions: Limited to the preserved summary’s selected strategy/population/endpoint/period. It does not replace numbers for other strategies/trials/endpoints or unread external materials.
Why this condition is needed: An applied item distinguishing distinction between 5% response, advance success/importance criteria and clinical outcomes to connect the selected question’s needed materials with current materials.
Referenced methods: M15 §15.3.1–15.3.3; custom application; M03 §3.2.4; custom extension boundary; M08 Table 8.2.a, M04 §4.6.3; custom application

N23 · Concurrent management, medication and lifestyle

Required materials and conditions: Concurrent conditions/medication, lifestyle/clinical exposure and responder outcomes
Conditions for verification: Corresponding original materials and analysis scope for concurrent conditions/medication, lifestyle/clinical exposure and responder outcomes must be available and unverified matters distinguishable. Preserved wording is linked here; existing content review remains incomplete.
Requirement and applicability: Required
Application exceptions: Limited to the preserved summary’s selected strategy/population/endpoint/period. It does not replace numbers for other strategies/trials/endpoints or unread external materials.
Why this condition is needed: An applied item distinguishing concurrent conditions/medication, lifestyle/clinical exposure and responder outcomes to connect the selected question’s needed materials with current materials.
Referenced methods: M03 §3.2.3, M08 §8.2.2–8.2.3; own application; M03 §3.2.2–3.2.3; reverse-direction labels and test adaptations are our own design

N24 · NIH public support

Required materials and conditions: Distinction between funder/grant, support roles and independence
Conditions for verification: Corresponding original materials and analysis scope for distinction between funder/grant, support roles and independence must be available and unverified matters distinguishable. Preserved wording is linked here; existing content review remains incomplete.
Requirement and applicability: Required
Application exceptions: Limited to the preserved summary’s selected strategy/population/endpoint/period. It does not replace numbers for other strategies/trials/endpoints or unread external materials.
Why this condition is needed: An applied item distinguishing distinction between funder/grant, support roles and independence to connect the selected question’s needed materials with current materials.
Referenced methods: Chamgap's own conditions for independence and attribution. The official methodological sections used in this example do not validate every detail of these items.

N25 · Non-reporting of support in the pivotal paper

Required materials and conditions: Category-specific scope of commercial, in-kind, outsourced-analysis/writing and publication support
Conditions for verification: Corresponding original materials and analysis scope for category-specific scope of commercial, in-kind, outsourced-analysis/writing and publication support must be available and unverified matters distinguishable. Preserved wording is linked here; existing content review remains incomplete.
Requirement and applicability: Required
Application exceptions: Limited to the preserved summary’s selected strategy/population/endpoint/period. It does not replace numbers for other strategies/trials/endpoints or unread external materials.
Why this condition is needed: An applied item distinguishing category-specific scope of commercial, in-kind, outsourced-analysis/writing and publication support to connect the selected question’s needed materials with current materials.
Referenced methods: Chamgap independence/attribution conditions. The referenced official method sections do not certify every detail of these items; Data collection/selection principles in M04 §4.5–4.6; Access/reading separation and hyperlink rules are Chamgap design

N26 · Later author relationships and disclosure timing

Required materials and conditions: Distinction between later WW/Coeus disclosures and original-trial timing/roles
Conditions for verification: Corresponding original materials and analysis scope for distinction between later WW/Coeus disclosures and original-trial timing/roles must be available and unverified matters distinguishable. Preserved wording is linked here; existing content review remains incomplete.
Requirement and applicability: Required
Application exceptions: Limited to the preserved summary’s selected strategy/population/endpoint/period. It does not replace numbers for other strategies/trials/endpoints or unread external materials.
Why this condition is needed: An applied item distinguishing distinction between later WW/Coeus disclosures and original-trial timing/roles to connect the selected question’s needed materials with current materials.
Referenced methods: Chamgap’s custom independence/attribution conditions. The official methodology sections used in this pilot do not guarantee all these detailed items; M04 §4.5, §4.6.3; current conversion limits reflect review scope and custom design; M04 §4.6.1–4.6.2 distinction between studies and reports; cohort/outcome linkage is custom application

N27 · References to null results from other programs

Required materials and conditions: Directness of Track’s bundle versus app-only/low-intensity programs
Conditions for verification: Corresponding original materials and analysis scope for directness of Track’s bundle versus app-only/low-intensity programs must be available and unverified matters distinguishable. Preserved wording is linked here; existing content review remains incomplete.
Requirement and applicability: Required
Application exceptions: Limited to the preserved summary’s selected strategy/population/endpoint/period. It does not replace numbers for other strategies/trials/endpoints or unread external materials.
Why this condition is needed: An applied item distinguishing directness of Track’s bundle versus app-only/low-intensity programs to connect the selected question’s needed materials with current materials.
Referenced methods: M04 §4.6.3, M15 §15.3.1–15.3.3; status separation is custom design; M04 §4.6.1–4.6.2 distinction between studies and reports; cohort/outcome linkage is custom application; M03 §3.2.2–3.2.3; reverse-direction labeling and test adaptation are custom design

N28 · Same report, sibling sheets and independence

Required materials and conditions: Mean/responder, report/registration and group/time-point relationships
Conditions for verification: Corresponding original materials and analysis scope for mean/responder, report/registration and group/time-point relationships must be available and unverified matters distinguishable. Preserved wording is linked here; existing content review remains incomplete.
Requirement and applicability: Required
Application exceptions: Limited to the preserved summary’s selected strategy/population/endpoint/period. It does not replace numbers for other strategies/trials/endpoints or unread external materials.
Why this condition is needed: An applied item distinguishing mean/responder, report/registration and group/time-point relationships to connect the selected question’s needed materials with current materials.
Referenced methods: Study/report distinction in M04 §4.6.1–4.6.2; Cohort/outcome linkage is Chamgap application; M04 §4.6.1–4.6.2 and M15 §15.3.1; Chamgap application

N29 · Persistence and applicability to other compositions/populations

Required materials and conditions: Distinction between Track responder results and long-term/stand-alone-app/other-population effects
Conditions for verification: Corresponding original materials and analysis scope for distinction between Track responder results and long-term/stand-alone-app/other-population effects must be available and unverified matters distinguishable. Preserved wording is linked here; existing content review remains incomplete.
Requirement and applicability: Required
Application exceptions: Limited to the preserved summary’s selected strategy/population/endpoint/period. It does not replace numbers for other strategies/trials/endpoints or unread external materials.
Why this condition is needed: An applied item distinguishing distinction between Track responder results and long-term/stand-alone-app/other-population effects to connect the selected question’s needed materials with current materials.
Referenced methods: M03 §3.2.1–3.2.4; dose, persistence and effect-modification details are custom design; M03 §3.2.4; custom extension boundary; M03 §3.2.2–3.2.3; reverse-direction labeling and test adaptation are custom design

N30 · Unknown safety and collection gaps

Required materials and conditions: Prespecification, collection/denominators and follow-up for adverse events
Conditions for verification: Corresponding original materials and analysis scope for prespecification, collection/denominators and follow-up for adverse events must be available and unverified matters distinguishable. Preserved wording is linked here; existing content review remains incomplete.
Requirement and applicability: Supplementary
Application exceptions: Supplements safety-data gaps for the selected subclaim. Mean weight, 5% responder results and parent caution wording are not used to judge safety or generate harm incidence or new use instructions.
Why this condition is needed: An applied item distinguishing prespecification, collection/denominators and follow-up for adverse events to connect the selected question’s needed materials with current materials.
Referenced methods: M19 §19.1.2–19.2.4; detailed distinctions are Chamgap’s own design; M19 §19.1.2–19.2.4; Chamgap application; M19 §19.1.2–19.2.4; Chamgap application; M19 §19.1.2–19.2.4; Chamgap application

N31 · Parent/subclaim, Korean/English, corrections and history

Required materials and conditions: Separate preservation of original values/axes, reference dates and verification narratives
Conditions for verification: Corresponding original materials and analysis scope for separate preservation of original values/axes, reference dates and verification narratives must be available and unverified matters distinguishable. Preserved wording is linked here; existing content review remains incomplete.
Requirement and applicability: Required
Application exceptions: Limited to the preserved summary’s selected strategy/population/endpoint/period. It does not replace numbers for other strategies/trials/endpoints or unread external materials.
Why this condition is needed: An applied item distinguishing separate preservation of original values/axes, reference dates and verification narratives to connect the selected question’s needed materials with current materials.
Referenced methods: M04 §4.5, §4.6.3; limits of this material conversion follow the review scope and internal design; M03 §3.1, §3.2.1–3.2.4 question-clarification principles; detailed separation rules are internally designed

N32 · Summary reading, external links and updates

Required materials and conditions: Actually read scope and access status of external materials
Conditions for verification: Corresponding original materials and analysis scope for actually read scope and access status of external materials must be available and unverified matters distinguishable. Preserved wording is linked here; existing content review remains incomplete.
Requirement and applicability: Required
Application exceptions: Limited to the preserved summary’s selected strategy/population/endpoint/period. It does not replace numbers for other strategies/trials/endpoints or unread external materials.
Why this condition is needed: An applied item distinguishing actually read scope and access status of external materials to connect the selected question’s needed materials with current materials.
Referenced methods: M04 §4.5–4.6 material collection/selection principles; acquisition/reading separation and hyperlink specifications are internally designed; M04 §4.5, §4.6.3; limits of this material conversion follow the review scope and internal design

Referenced methods and the sections actually reviewed

M03 · Cochrane Handbook 6.5 (2024), chapter updated 2023-08

Official methodology · §3.1, §3.2.1–3.2.3, MECIR C5/C7/C13

Referenced principle: Clearly record the question, eligibility conditions and reasons for changes, and distinguish variations in interventions.
Extent of review: Preserved method HTML copies; no current method-content re-review or official tool execution

M04 · Cochrane Handbook 6.5.1 (2025), chapter updated 2025-03

Official methodology · §4.5, §4.6.1–4.6.3, MECIR C42

Referenced principle: Distinguish studies from reports and link them; do not omit a study solely because results are unreported.
Extent of review: Preserved method HTML copies; no current method-content re-review or official tool execution

M08 · Cochrane Handbook 6.5 (2024), chapter updated 2019-10

Official methodology · §8.1–8.2.3, Table 8.2.a

Referenced principle: Define the outcome and effect of interest, then examine randomization, deviations, missing data, measurement and selective reporting.
Extent of review: Preserved method HTML copies; no current method-content re-review or official tool execution

M15 · Cochrane Handbook 6.5 (2024), chapter updated 2023-08

Official methodology · §15.2.4, §15.3.1–15.3.3

Referenced principle: Distinguish effect estimates, intervals, importance and applicability. Sample size alone does not determine precision.
Extent of review: Preserved method HTML copies; no current method-content re-review or official tool execution

M19 · Cochrane Handbook 6.5 (2024), chapter updated 2019-10

Official methodology · §19.1.2, §19.2.1–19.2.4

Referenced principle: Harm questions may require different designs, populations and follow-up from efficacy questions. Case reports do not establish incidence rates.
Extent of review: Preserved method HTML copies; no current method-content re-review or official tool execution

What the statuses mean

Met: Status for necessary evidence confirmed after existing content review. No completion is declared in the current presentation.
Partly verified: Some information in the stored summary is linked into the table. External comparison/content review is not complete.
Unverified: The article leaves this unverified, or required material is absent from the current stored summary. This is distinct from zero, absence or safety.
Review incomplete: Existing content review remains incomplete.
Not reported: Not reported within the stored material actually read; not extended to the entire primary paper.
Inaccessible: Means an actual access failure. Access not attempted here is not assigned this state.
Not applicable: Not used as a substitute for an evidence gap.
Conflicting data: Requires an observed disagreement under the same comparison criteria; not automatically judged in this production.
Insufficient evidence for the conditions: Marks a gap in additional material required by the selected conditions; not a new efficacy grade.

Change history

2026-10-14 · Public page/material version 1.0

Public pages and materials were prepared from the existing 32 items. No new clinical search, verification-status change or scoring was performed.

The stored-material review date (Not recorded) and original evidence cut-off (2026-08-26) were retained unchanged.

Researcher downloads

These materials provide the same evidence, scope and verification status as this page.

View all item details

N01 · Selected 5% claim and original grade

Current findings: The selected subclaim is “At least 5% weight loss,” with grade C and a note of a secondary responder result of 40% versus 17%. Subclaim score/status/axes are absent; parent C56 is not used to fill the subclaim score.
Verification status: Partly verified
Materials actually read: Summary read; external material unread
Why unverified: Only the relevant information in the preserved summary is recorded; detailed originals remain unread and existing content review incomplete. Subclaim score, status and axes are absent. The primary mean endpoint and secondary responder endpoint are not combined. Existing content review remains incomplete.
Reason for missing information: Subclaim score, status and axes are absent. The primary mean endpoint and secondary responder endpoint are not combined.
Required materials and conditions: Distinction between the original responder question/grade and the parent mean-weight verdict
Materials to obtain first: Original selected subclaim and parent verdict, and user correction comments
Further research: A proposed follow-up comparison specifying the responder question and hierarchy; no new investigation, calculation or trial was performed.
Remaining uncertainty: This record links preserved-summary statements; it does not establish external-paper comparison, a new efficacy verdict or completed content review.
Conditions for verification: Corresponding original materials and analysis scope for distinction between the original responder question/grade and the parent mean-weight verdict must be available and unverified matters distinguishable. Preserved wording is linked here; existing content review remains incomplete.
Why this condition is needed: An applied item distinguishing distinction between the original responder question/grade and the parent mean-weight verdict to connect the selected question’s needed materials with current materials.
Application exceptions: Limited to the preserved summary’s selected strategy/population/endpoint/period. It does not replace numbers for other strategies/trials/endpoints or unread external materials.
Referenced methods: M03 §3.1, §3.2.1–3.2.4 question-clarification principles; detailed separation rules are custom design; M03 §3.2.4, M15 §15.3.1–15.3.3; question-specific outcome adaptation is custom design; M04 §4.5, §4.6.3; limits on current material conversion reflect the review scope and custom design

Related sources S01

N02 · Definition of the 5% threshold

Current findings: The original question concerns attaining the threshold of at least 5% weight loss. This is not converted into mean change in kg, individual final weight or change in every participant.
Verification status: Partly verified
Materials actually read: Summary read; external material unread
Why unverified: Only the relevant information in the preserved summary is recorded; detailed originals remain unread and existing content review incomplete. Reference weight/calculation formula, rounding/boundaries, evaluation windows, measurement selection and details of advance definitions remain unverified. Existing content review remains incomplete.
Reason for missing information: Reference weight/calculation formula, rounding/boundaries, evaluation windows, measurement selection and details of advance definitions remain unverified.
Required materials and conditions: Threshold, reference weight, calculation/time point and responder-adjudication rules
Materials to obtain first: Responder definitions, baseline/final measurements and adjudication rules
Further research: A proposed follow-up study specifying thresholds, measurement and time points; no new investigation, calculation or trial was performed.
Remaining uncertainty: This record links preserved-summary statements; it does not establish external-paper comparison, a new efficacy verdict or completed content review.
Conditions for verification: Corresponding original materials and analysis scope for threshold, reference weight, calculation/time point and responder-adjudication rules must be available and unverified matters distinguishable. Preserved wording is linked here; existing content review remains incomplete.
Why this condition is needed: An applied item distinguishing threshold, reference weight, calculation/time point and responder-adjudication rules to connect the selected question’s needed materials with current materials.
Application exceptions: Limited to the preserved summary’s selected strategy/population/endpoint/period. It does not replace numbers for other strategies/trials/endpoints or unread external materials.
Referenced methods: M03 §3.2.4, M15 §15.3.1–15.3.3; question-specific outcome adaptation is custom design; M08 §8.2.2, M15 §15.3.1; custom application; M08 Table 8.2.a, M04 §4.6.3; custom application

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N03 · 40% versus 17% and P value

Current findings: The original result was at least 5% weight loss in 40% versus 17%, P<0.001. No new proportion difference, RR/OR, NNT, CI or event count is calculated.
Verification status: Partly verified
Materials actually read: Summary read; external material unread
Why unverified: Only the relevant information in the preserved summary is recorded; detailed originals remain unread and existing content review incomplete. Analysis denominators/event counts for each proportion, exact test/model, CI and distinction between observed/estimated values remain unverified. Existing content review remains incomplete.
Reason for missing information: Analysis denominators/event counts for each proportion, exact test/model, CI and distinction between observed/estimated values remain unverified.
Required materials and conditions: Distinction between original proportions, group correspondence, P value and new arithmetic
Materials to obtain first: Responder-result tables and original denominator/event/effect/CI data
Further research: A proposed study reporting proportions together with uncertainty and denominators; no new investigation, calculation or trial was performed.
Remaining uncertainty: This record links preserved-summary statements; it does not establish external-paper comparison, a new efficacy verdict or completed content review.
Conditions for verification: Corresponding original materials and analysis scope for distinction between original proportions, group correspondence, P value and new arithmetic must be available and unverified matters distinguishable. Preserved wording is linked here; existing content review remains incomplete.
Why this condition is needed: An applied item distinguishing distinction between original proportions, group correspondence, P value and new arithmetic to connect the selected question’s needed materials with current materials.
Application exceptions: Limited to the preserved summary’s selected strategy/population/endpoint/period. It does not replace numbers for other strategies/trials/endpoints or unread external materials.
Referenced methods: M15 §15.3.1–15.3.3; CHAMGAP adaptation; M08 Table 8.2.a, M15 §15.3, M19 §19.1.2–19.2.4; Design-specific adaptations are designed by CHAMGAP; M08 §8.2.2, M15 §15.3.1; CHAMGAP adaptation

Related sources S01

N04 · Responder denominators and event counts

Current findings: 351 randomized participants (176/175) describe the original population. These are not multiplied by 40%/17% to create event counts or used to fill the effective denominator of each proportion.
Verification status: Partly verified
Materials actually read: Summary read; external material unread
Why unverified: Only the relevant information in the preserved summary is recorded; detailed originals remain unread and existing content review incomplete. Effective denominators for each proportion, responder counts, inclusion/exclusion and measured/estimated criteria remain unverified. Existing content review remains incomplete.
Reason for missing information: Effective denominators for each proportion, responder counts, inclusion/exclusion and measured/estimated criteria remain unverified.
Required materials and conditions: Randomized, observed and model denominators and actual responder counts
Materials to obtain first: Responder denominators/events, participant flow and analysis-population data
Further research: A proposed study reporting enrolled, observed and estimated denominators separately; no new investigation, calculation or trial was performed.
Remaining uncertainty: This record links preserved-summary statements; it does not establish external-paper comparison, a new efficacy verdict or completed content review.
Conditions for verification: Corresponding original materials and analysis scope for randomized, observed and model denominators and actual responder counts must be available and unverified matters distinguishable. Preserved wording is linked here; existing content review remains incomplete.
Why this condition is needed: An applied item distinguishing randomized, observed and model denominators and actual responder counts to connect the selected question’s needed materials with current materials.
Application exceptions: Limited to the preserved summary’s selected strategy/population/endpoint/period. It does not replace numbers for other strategies/trials/endpoints or unread external materials.
Referenced methods: M08 Table 8.2.a, M15 §15.3 and M19 §19.1.2–19.2.4; Design-specific adaptation is Chamgap design; M08 §8.2.2 and M15 §15.3.1; Chamgap application

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N05 · Proportion effects, CIs and precision

Current findings: Original proportions and P value are preserved. Proportion differences, relative effects, CIs or individual success probabilities unlinked in the manuscript are not newly created.
Verification status: Partly verified
Materials actually read: Summary read; external material unread
Why unverified: Only the relevant information in the preserved summary is recorded; detailed originals remain unread and existing content review incomplete. Planned effect measures, exact estimates, CIs and importance/success criteria remain unverified. Existing content review remains incomplete.
Reason for missing information: Planned effect measures, exact estimates, CIs and importance/success criteria remain unverified.
Required materials and conditions: Original proportions, prespecified effect measures, CIs and clinical importance
Materials to obtain first: Original proportion-effect/CI data and prespecified importance criteria
Further research: A proposed follow-up study disclosing effect measures and uncertainty; no new investigation, calculation or trial was performed.
Remaining uncertainty: This record links preserved-summary statements; it does not establish external-paper comparison, a new efficacy verdict or completed content review.
Conditions for verification: Corresponding original materials and analysis scope for original proportions, prespecified effect measures, CIs and clinical importance must be available and unverified matters distinguishable. Preserved wording is linked here; existing content review remains incomplete.
Why this condition is needed: An applied item distinguishing original proportions, prespecified effect measures, CIs and clinical importance to connect the selected question’s needed materials with current materials.
Application exceptions: Limited to the preserved summary’s selected strategy/population/endpoint/period. It does not replace numbers for other strategies/trials/endpoints or unread external materials.
Referenced methods: M15 §15.3.1–15.3.3; custom application; M08 Table 8.2.a, M15 §15.3, M19 §19.1.2–19.2.4; design-specific adaptation is custom design; M08 Table 8.2.a, M04 §4.6.3; custom application

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N06 · Mean change is a different endpoint

Current findings: Mean change of −4.0 kg versus −0.1 kg and a between-group difference of −3.8 kg (95% CI −5.0 to −2.5), P<0.001, form a separate primary endpoint. The 5% proportions, event counts or individual weight loss are not calculated from these.
Verification status: Partly verified
Materials actually read: Summary read; external material unread
Why unverified: Only the relevant information in the preserved summary is recorded; detailed originals remain unread and existing content review incomplete. Individual baseline/change distributions and data linking mean and responder outcomes remain unverified. Existing content review remains incomplete.
Reason for missing information: Individual baseline/change distributions and data linking mean and responder outcomes remain unverified.
Required materials and conditions: Distinction between continuous means and threshold-attainment distributions/proportions
Materials to obtain first: Individual/group distributions and results for each endpoint
Further research: A proposed follow-up trial distinguishing mean and responder endpoints; no new investigation, calculation or trial was performed.
Remaining uncertainty: This record links preserved-summary statements; it does not establish external-paper comparison, a new efficacy verdict or completed content review.
Conditions for verification: Corresponding original materials and analysis scope for distinction between continuous means and threshold-attainment distributions/proportions must be available and unverified matters distinguishable. Preserved wording is linked here; existing content review remains incomplete.
Why this condition is needed: An applied item distinguishing distinction between continuous means and threshold-attainment distributions/proportions to connect the selected question’s needed materials with current materials.
Application exceptions: Limited to the preserved summary’s selected strategy/population/endpoint/period. It does not replace numbers for other strategies/trials/endpoints or unread external materials.
Referenced methods: M03 §3.2.4, M15 §15.3.1–15.3.3; question-specific outcome adaptations are Chamgap's own design; M08 §8.2.2, M15 §15.3.1; Chamgap's own application; M15 §15.3.1–15.3.3; Chamgap's own application

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N07 · Secondary endpoint and prespecified hierarchy

Current findings: The manuscript identifies at least 5% weight loss as a secondary responder result. This is not upgraded into a new primary endpoint, independent confirmatory trial or prespecified success threshold.
Verification status: Partly verified
Materials actually read: Summary read; external material unread
Why unverified: Only the relevant information in the preserved summary is recorded; detailed originals remain unread and existing content review incomplete. Pre-recruitment specification of responder definitions/analyses, test order, change history and estimation models remain unverified. Existing content review remains incomplete.
Reason for missing information: Pre-recruitment specification of responder definitions/analyses, test order, change history and estimation models remain unverified.
Required materials and conditions: Distinction between the primary mean endpoint and secondary 5% responder result
Materials to obtain first: Responder hierarchy/plans in registration, protocol and SAP
Further research: A proposed study distinguishing the primary endpoint from prespecified responder analyses; no new investigation, calculation or trial was performed.
Remaining uncertainty: This record links preserved-summary statements; it does not establish external-paper comparison, a new efficacy verdict or completed content review.
Conditions for verification: Corresponding original materials and analysis scope for distinction between the primary mean endpoint and secondary 5% responder result must be available and unverified matters distinguishable. Preserved wording is linked here; existing content review remains incomplete.
Why this condition is needed: An applied item distinguishing distinction between the primary mean endpoint and secondary 5% responder result to connect the selected question’s needed materials with current materials.
Application exceptions: Limited to the preserved summary’s selected strategy/population/endpoint/period. It does not replace numbers for other strategies/trials/endpoints or unread external materials.
Referenced methods: M08 Table 8.2.a, M04 §4.6.3; internal application; M04 §4.6.3, M15 §15.3.1–15.3.3; status separation is internally designed; M04 §4.6.1–4.6.2 distinguishes studies from reports; cohort/outcome links are an internal application

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N08 · Measured weight and responder-adjudication values

Current findings: Primary weight change used standardized measurement at research visits. This is distinguished from daily smart-scale/app entries and self-report; actual values/visit rules used for the 5% proportions are not filled in.
Verification status: Partly verified
Materials actually read: Summary read; external material unread
Why unverified: Only the relevant information in the preserved summary is recorded; detailed originals remain unread and existing content review incomplete. Measurement sources, evaluation windows, equipment/conditions and valid baseline/final values for responder adjudication remain unverified. Existing content review remains incomplete.
Reason for missing information: Measurement sources, evaluation windows, equipment/conditions and valid baseline/final values for responder adjudication remain unverified.
Required materials and conditions: Correspondence between visit weight, self-monitoring/self-report and proportion calculations
Materials to obtain first: Responder adjudication/measurement protocols and original weight data
Further research: A proposed study linking measured/remote measurements with responder calculations; no new investigation, calculation or trial was performed.
Remaining uncertainty: This record links preserved-summary statements; it does not establish external-paper comparison, a new efficacy verdict or completed content review.
Conditions for verification: Corresponding original materials and analysis scope for correspondence between visit weight, self-monitoring/self-report and proportion calculations must be available and unverified matters distinguishable. Preserved wording is linked here; existing content review remains incomplete.
Why this condition is needed: An applied item distinguishing correspondence between visit weight, self-monitoring/self-report and proportion calculations to connect the selected question’s needed materials with current materials.
Application exceptions: Limited to the preserved summary’s selected strategy/population/endpoint/period. It does not replace numbers for other strategies/trials/endpoints or unread external materials.
Referenced methods: M03 §3.2.4, M15 §15.3.1–15.3.3; question-specific outcome adaptations are internally designed; M08 Table 8.2.a, M03 §3.2.4; internal application; M08 §8.2.2, M15 §15.3.1; internal application

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N09 · Population, comorbidities and recruitment

Current findings: 351 people aged 21–65 at community health centers had obesity and at least one of hypertension, diabetes or hyperlipidemia. This is not extended into the probability of attaining 5% loss in other populations.
Verification status: Partly verified
Materials actually read: Summary read; external material unread
Why unverified: Only the relevant information in the preserved summary is recorded; detailed originals remain unread and existing content review incomplete. Detailed eligibility, baseline weight/condition distributions, recruitment/exclusions and group balance remain unverified. Existing content review remains incomplete.
Reason for missing information: Detailed eligibility, baseline weight/condition distributions, recruitment/exclusions and group balance remain unverified.
Required materials and conditions: Obese population aged 21–65 with baseline conditions and applicability scope
Materials to obtain first: Eligibility, baseline-characteristics and recruitment tables
Further research: A proposed follow-up study specifying applicability by population; no new investigation, calculation or trial was performed.
Remaining uncertainty: This record links preserved-summary statements; it does not establish external-paper comparison, a new efficacy verdict or completed content review.
Conditions for verification: Corresponding original materials and analysis scope for obese population aged 21–65 with baseline conditions and applicability scope must be available and unverified matters distinguishable. Preserved wording is linked here; existing content review remains incomplete.
Why this condition is needed: An applied item distinguishing obese population aged 21–65 with baseline conditions and applicability scope to connect the selected question’s needed materials with current materials.
Application exceptions: Limited to the preserved summary’s selected strategy/population/endpoint/period. It does not replace numbers for other strategies/trials/endpoints or unread external materials.
Referenced methods: M03 §3.2.1; Detailed population conditions are Chamgap design; M03 §3.2.1–3.2.4; Dose, duration and effect-modifier details are Chamgap design

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N10 · Attribution within multicomponent Track

Current findings: The intervention bundled an app, cellular smart scale, 18 dietitian calls and clinician counseling. The proportion attaining 5% loss is not converted into an effect of a stand-alone app or a specific component.
Verification status: Partly verified
Materials actually read: Summary read; external material unread
Why unverified: Only the relevant information in the preserved summary is recorded; detailed originals remain unread and existing content review incomplete. Independent component effects, component-separation/combination designs and contributions of actual use remain unverified. Existing content review remains incomplete.
Reason for missing information: Independent component effects, component-separation/combination designs and contributions of actual use remain unverified.
Required materials and conditions: The full bundle versus individual effects of app/counseling and other components
Materials to obtain first: Full intervention composition, delivery/use and component-separation designs
Further research: A proposed follow-up comparison distinguishing bundle and component attribution; no new investigation, calculation or trial was performed.
Remaining uncertainty: This record links preserved-summary statements; it does not establish external-paper comparison, a new efficacy verdict or completed content review.
Conditions for verification: Corresponding original materials and analysis scope for the full bundle versus individual effects of app/counseling and other components must be available and unverified matters distinguishable. Preserved wording is linked here; existing content review remains incomplete.
Why this condition is needed: An applied item distinguishing the full bundle versus individual effects of app/counseling and other components to connect the selected question’s needed materials with current materials.
Application exceptions: Limited to the preserved summary’s selected strategy/population/endpoint/period. It does not replace numbers for other strategies/trials/endpoints or unread external materials.
Referenced methods: M03 §3.2.2–3.2.3; Reverse-direction labels and assessment adaptation are Chamgap design; M03 §3.2.3 and M08 §8.2.2–8.2.3; Chamgap application

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N11 · Component plans and actual use

Current findings: The manuscript records app self-monitoring/tailored feedback, daily cellular-scale weighing, 18 calls and counseling based on electronic-record recommendations. Plans are not used to imply actual completion by every participant.
Verification status: Partly verified
Materials actually read: Summary read; external material unread
Why unverified: Only the relevant information in the preserved summary is recorded; detailed originals remain unread and existing content review incomplete. Component-specific delivery/usage, adherence, discontinuation, contact intensity and differences in clinical/concurrent management remain unverified. Existing content review remains incomplete.
Reason for missing information: Component-specific delivery/usage, adherence, discontinuation, contact intensity and differences in clinical/concurrent management remain unverified.
Required materials and conditions: Delivery/exposure for app feedback, daily scale use, 18 calls and clinical integration
Materials to obtain first: Delivery, use and contact records for the app/device/counseling/clinical care
Further research: A proposed follow-up study distinguishing plans from actual exposure and response; no new investigation, calculation or trial was performed.
Remaining uncertainty: This record links preserved-summary statements; it does not establish external-paper comparison, a new efficacy verdict or completed content review.
Conditions for verification: Corresponding original materials and analysis scope for delivery/exposure for app feedback, daily scale use, 18 calls and clinical integration must be available and unverified matters distinguishable. Preserved wording is linked here; existing content review remains incomplete.
Why this condition is needed: An applied item distinguishing delivery/exposure for app feedback, daily scale use, 18 calls and clinical integration to connect the selected question’s needed materials with current materials.
Application exceptions: Limited to the preserved summary’s selected strategy/population/endpoint/period. It does not replace numbers for other strategies/trials/endpoints or unread external materials.
Referenced methods: M03 §3.2.3, M08 §8.2.2–8.2.3; own application; M03 §3.2.2–3.2.3; reverse-direction labels and test adaptations are our own design

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N12 · Usual-care control

Current findings: The comparison involved 176 intervention participants versus 175 receiving usual care. Usual care is not described as no management/contact, and equal support in all respects is not established.
Verification status: Partly verified
Materials actually read: Summary read; external material unread
Why unverified: Only the relevant information in the preserved summary is recorded; detailed originals remain unread and existing content review incomplete. Control content, contact/support, additional programs, crossover use and baseline-condition management remain unverified. Existing content review remains incomplete.
Reason for missing information: Control content, contact/support, additional programs, crossover use and baseline-condition management remain unverified.
Required materials and conditions: Actual control management, contact and additional-exposure conditions
Materials to obtain first: Usual-care and concurrent-exposure/contact records
Further research: Proposed follow-up trial disclosing actual comparison conditions; no new investigation, calculation or trial was performed in this production.
Remaining uncertainty: This record links preserved-summary statements; it does not establish external-paper comparison, a new efficacy verdict or completed content review.
Conditions for verification: Corresponding original materials and analysis scope for actual control management, contact and additional-exposure conditions must be available and unverified matters distinguishable. Preserved wording is linked here; existing content review remains incomplete.
Why this condition is needed: An applied item distinguishing actual control management, contact and additional-exposure conditions to connect the selected question’s needed materials with current materials.
Application exceptions: Limited to the preserved summary’s selected strategy/population/endpoint/period. It does not replace numbers for other strategies/trials/endpoints or unread external materials.
Referenced methods: M03 §3.2.2–3.2.3; Reverse-direction labels and assessment adaptation are Chamgap design; M03 §3.2.3 and M08 §8.2.2–8.2.3; Chamgap application

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N13 · 12-month assessment, maintenance and regain

Current findings: The responder result in the 12-month study context is preserved. Attaining the threshold once during follow-up, sustained attainment and maintenance/regain beyond 12 months are not made into the same outcome.
Verification status: Partly verified
Materials actually read: Summary read; external material unread
Why unverified: Only the relevant information in the preserved summary is recorded; detailed originals remain unread and existing content review incomplete. Exact evaluation windows, earlier responses, maintained attainment/regain and long-term/discontinuation follow-up remain unverified. Existing content review remains incomplete.
Reason for missing information: Exact evaluation windows, earlier responses, maintained attainment/regain and long-term/discontinuation follow-up remain unverified.
Required materials and conditions: Distinction between the selected responder time point and persistence during or beyond follow-up
Materials to obtain first: Responder visit/time-point definitions and long-term follow-up materials
Further research: A proposed study reporting threshold attainment separately from maintenance/regain; no new investigation, calculation or trial was performed.
Remaining uncertainty: This record links preserved-summary statements; it does not establish external-paper comparison, a new efficacy verdict or completed content review.
Conditions for verification: Corresponding original materials and analysis scope for distinction between the selected responder time point and persistence during or beyond follow-up must be available and unverified matters distinguishable. Preserved wording is linked here; existing content review remains incomplete.
Why this condition is needed: An applied item distinguishing distinction between the selected responder time point and persistence during or beyond follow-up to connect the selected question’s needed materials with current materials.
Application exceptions: Limited to the preserved summary’s selected strategy/population/endpoint/period. It does not replace numbers for other strategies/trials/endpoints or unread external materials.
Referenced methods: M03 §3.2.4, M15 §15.3.1–15.3.3; question-specific outcome adaptations are internally designed; M03 §3.2.1–3.2.4; dose, duration and effect-modification details are internally designed

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N14 · Randomization and allocation concealment

Current findings: The manuscript records sequence generation by a statistician and concealment from study staff before allocation. It is not described as current original-source review or verification of allocation records.
Verification status: Partly verified
Materials actually read: Summary read; external material unread
Why unverified: Only the relevant information in the preserved summary is recorded; detailed originals remain unread and existing content review incomplete. Allocation records, implementation/exceptions, baseline balance and correspondence with the original protocol remain unread. Existing content review remains incomplete.
Reason for missing information: Allocation records, implementation/exceptions, baseline balance and correspondence with the original protocol remain unread.
Required materials and conditions: Historical allocation-procedure narrative and current access to originals
Materials to obtain first: Original allocation/concealment, baseline and protocol materials
Further research: Proposed follow-up trial disclosing allocation procedures; no new investigation, calculation or trial was performed in this production.
Remaining uncertainty: This record links preserved-summary statements; it does not establish external-paper comparison, a new efficacy verdict or completed content review.
Conditions for verification: Corresponding original materials and analysis scope for historical allocation-procedure narrative and current access to originals must be available and unverified matters distinguishable. Preserved wording is linked here; existing content review remains incomplete.
Why this condition is needed: An applied item distinguishing historical allocation-procedure narrative and current access to originals to connect the selected question’s needed materials with current materials.
Application exceptions: Limited to the preserved summary’s selected strategy/population/endpoint/period. It does not replace numbers for other strategies/trials/endpoints or unread external materials.
Referenced methods: M08 §8.1–8.2.3; internal application; M04 §4.5–4.6 collection/selection principles; access/reading separation and hyperlink specifications are internally designed

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N15 · Assessor masking and participant expectations

Current findings: The manuscript records masked measurement staff and unmasked participants. This is not extended into verification of every responder-calculation/analysis role or exclusion of expectation effects.
Verification status: Partly verified
Materials actually read: Summary read; external material unread
Why unverified: Only the relevant information in the preserved summary is recorded; detailed originals remain unread and existing content review incomplete. Original materials on responder-adjudication/analysis roles, maintained masking and expectation/behavior effects remain unread. Existing content review remains incomplete.
Reason for missing information: Original materials on responder-adjudication/analysis roles, maintained masking and expectation/behavior effects remain unread.
Required materials and conditions: Scope of masking for outcome assessors and participants
Materials to obtain first: Masking-role materials for measurement, adjudication and analysis
Further research: A proposed study distinguishing masking from participant behavior/expectation scope; no new investigation, calculation or trial was performed.
Remaining uncertainty: This record links preserved-summary statements; it does not establish external-paper comparison, a new efficacy verdict or completed content review.
Conditions for verification: Corresponding original materials and analysis scope for scope of masking for outcome assessors and participants must be available and unverified matters distinguishable. Preserved wording is linked here; existing content review remains incomplete.
Why this condition is needed: An applied item distinguishing scope of masking for outcome assessors and participants to connect the selected question’s needed materials with current materials.
Application exceptions: Limited to the preserved summary’s selected strategy/population/endpoint/period. It does not replace numbers for other strategies/trials/endpoints or unread external materials.
Referenced methods: M08 Table 8.2.a, M03 §3.2.4; CHAMGAP adaptation; Material collection/selection principles in M04 §4.5–4.6; Separating access from reading and defining hyperlink behavior are designed by CHAMGAP

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N16 · ITT and responder-analysis population

Current findings: The manuscript’s statement of following ITT is preserved. It is not automatically transferred into details of populations/handling used for the 5% proportions or verification of observation of all participants.
Verification status: Partly verified
Materials actually read: Summary read; external material unread
Why unverified: Only the relevant information in the preserved summary is recorded; detailed originals remain unread and existing content review incomplete. Responder-analysis inclusion/exclusion, actual population definitions, primary/sensitivity analyses and PPS correspondence remain unverified. Existing content review remains incomplete.
Reason for missing information: Responder-analysis inclusion/exclusion, actual population definitions, primary/sensitivity analyses and PPS correspondence remain unverified.
Required materials and conditions: Overall ITT principle versus actual denominators/populations for secondary proportions
Materials to obtain first: Original responder-analysis populations, ITT application and sensitivity materials
Further research: A proposed study separately disclosing analysis populations for continuous and responder outcomes; no new investigation, calculation or trial was performed.
Remaining uncertainty: This record links preserved-summary statements; it does not establish external-paper comparison, a new efficacy verdict or completed content review.
Conditions for verification: Corresponding original materials and analysis scope for overall ITT principle versus actual denominators/populations for secondary proportions must be available and unverified matters distinguishable. Preserved wording is linked here; existing content review remains incomplete.
Why this condition is needed: An applied item distinguishing overall ITT principle versus actual denominators/populations for secondary proportions to connect the selected question’s needed materials with current materials.
Application exceptions: Limited to the preserved summary’s selected strategy/population/endpoint/period. It does not replace numbers for other strategies/trials/endpoints or unread external materials.
Referenced methods: M08 §8.2.2 and M15 §15.3.1: in-house application; M08 Table 8.2.a, M15 §15.3 and M19 §19.1.2–19.2.4: design-specific adaptation is in-house.

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N17 · Maximum-likelihood missing data and proportion handling

Current findings: The manuscript’s prespecified-model maximum-likelihood estimation is preserved. This is not used as identical verification of missing-data handling or denominator rules for responder proportions.
Verification status: Partly verified
Materials actually read: Summary read; external material unread
Why unverified: Only the relevant information in the preserved summary is recorded; detailed originals remain unread and existing content review incomplete. Missing-data adjudication, imputation/estimation, nonresponse handling and model/sensitivity for the 5% result remain unverified. Existing content review remains incomplete.
Reason for missing information: Missing-data adjudication, imputation/estimation, nonresponse handling and model/sensitivity for the 5% result remain unverified.
Required materials and conditions: Distinction between primary-analysis missing-data estimation and handling of unobserved responders
Materials to obtain first: Continuous/responder missing-data handling, models and sensitivity materials
Further research: A proposed study reporting endpoint-specific missing-data handling and effects separately; no new investigation, calculation or trial was performed.
Remaining uncertainty: This record links preserved-summary statements; it does not establish external-paper comparison, a new efficacy verdict or completed content review.
Conditions for verification: Corresponding original materials and analysis scope for distinction between primary-analysis missing-data estimation and handling of unobserved responders must be available and unverified matters distinguishable. Preserved wording is linked here; existing content review remains incomplete.
Why this condition is needed: An applied item distinguishing distinction between primary-analysis missing-data estimation and handling of unobserved responders to connect the selected question’s needed materials with current materials.
Application exceptions: Limited to the preserved summary’s selected strategy/population/endpoint/period. It does not replace numbers for other strategies/trials/endpoints or unread external materials.
Referenced methods: M08 Table 8.2.a, M15 §15.3 and M19 §19.1.2–19.2.4; Design-specific adaptation is Chamgap design; M08 §8.2.2 and M15 §15.3.1; Chamgap application

Related sources S01

N18 · Attrition, non-observation and missed visits

Current findings: 351 participants and 176/175 describe the randomized population. Without distinguishing observed/unobserved measurements and participant attrition, these are not used as outcomes for everyone or absence of missing-data effects.
Verification status: Unverified
Materials actually read: Summary read; external material unread
Why unverified: Information currently needed is unverified in the preserved summary. Visit/group-specific observed counts, attrition causes, response-related missingness and follow-up status remain unverified. Existing content review remains incomplete.
Reason for missing information: Visit/group-specific observed counts, attrition causes, response-related missingness and follow-up status remain unverified.
Required materials and conditions: Group-specific timing, causes and response effects of attrition/missingness
Materials to obtain first: Flow diagrams, visit/group denominators and attrition/follow-up materials
Further research: A proposed follow-up study disclosing effects of non-observation and response adjudication; no new investigation, calculation or trial was performed.
Remaining uncertainty: This record links preserved-summary statements; it does not establish external-paper comparison, a new efficacy verdict or completed content review.
Conditions for verification: Corresponding original materials and analysis scope for group-specific timing, causes and response effects of attrition/missingness must be available and unverified matters distinguishable. Preserved wording is linked here; existing content review remains incomplete.
Why this condition is needed: An applied item distinguishing group-specific timing, causes and response effects of attrition/missingness to connect the selected question’s needed materials with current materials.
Application exceptions: Limited to the preserved summary’s selected strategy/population/endpoint/period. It does not replace numbers for other strategies/trials/endpoints or unread external materials.
Referenced methods: M08 Table 8.2.a, M15 §15.3 and M19 §19.1.2–19.2.4; Design-specific adaptation is Chamgap design; M08 §8.2.2 and M15 §15.3.1; Chamgap application

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N19 · Proportion tests, within/between groups and adjustment

Current findings: The group correspondence of 40% versus 17% and P<0.001 is preserved as recorded. Within-group changes or rounded proportions are not converted into new adjusted effects or event risk ratios.
Verification status: Partly verified
Materials actually read: Summary read; external material unread
Why unverified: Only the relevant information in the preserved summary is recorded; detailed originals remain unread and existing content review incomplete. Exact tests, models/covariates, observed/estimated proportions, adjustment/advance plans and CIs remain unverified. Existing content review remains incomplete.
Reason for missing information: Exact tests, models/covariates, observed/estimated proportions, adjustment/advance plans and CIs remain unverified.
Required materials and conditions: Proportion contrasts and original model, test and adjustment conditions
Materials to obtain first: Original proportion-analysis models, contrasts, adjustments and CIs
Further research: A proposed study clearly reporting proportion estimands and tests; no new investigation, calculation or trial was performed.
Remaining uncertainty: This record links preserved-summary statements; it does not establish external-paper comparison, a new efficacy verdict or completed content review.
Conditions for verification: Corresponding original materials and analysis scope for proportion contrasts and original model, test and adjustment conditions must be available and unverified matters distinguishable. Preserved wording is linked here; existing content review remains incomplete.
Why this condition is needed: An applied item distinguishing proportion contrasts and original model, test and adjustment conditions to connect the selected question’s needed materials with current materials.
Application exceptions: Limited to the preserved summary’s selected strategy/population/endpoint/period. It does not replace numbers for other strategies/trials/endpoints or unread external materials.
Referenced methods: M08 §8.2.2, M15 §15.3.1; internal application; M15 §15.3.1–15.3.3; internal application; M08 Table 8.2.a, M04 §4.6.3; internal application

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N20 · Registration and advance responder plans

Current findings: Original NCT01827800, posting on 2013-04-10 and allocation starting on 2013-06-18 are preserved. Prospective registration and agreement with the primary 12-month mean endpoint do not substitute for verification of all 5% analysis conditions.
Verification status: Partly verified
Materials actually read: Summary read; external material unread
Why unverified: Only the relevant information in the preserved summary is recorded; detailed originals remain unread and existing content review incomplete. Secondary responder plans/definitions, pre-recruitment SAP, change history and full registration remain unread. Existing content review remains incomplete.
Reason for missing information: Secondary responder plans/definitions, pre-recruitment SAP, change history and full registration remain unread.
Required materials and conditions: NCT identifier and scope of advance plans for primary/secondary proportion endpoints
Materials to obtain first: Responder plans in registration history, protocol and SAP
Further research: A proposed study openly linking registration with actual secondary analyses; no new investigation, calculation or trial was performed.
Remaining uncertainty: This record links preserved-summary statements; it does not establish external-paper comparison, a new efficacy verdict or completed content review.
Conditions for verification: Corresponding original materials and analysis scope for nCT identifier and scope of advance plans for primary/secondary proportion endpoints must be available and unverified matters distinguishable. Preserved wording is linked here; existing content review remains incomplete.
Why this condition is needed: An applied item distinguishing nCT identifier and scope of advance plans for primary/secondary proportion endpoints to connect the selected question’s needed materials with current materials.
Application exceptions: Limited to the preserved summary’s selected strategy/population/endpoint/period. It does not replace numbers for other strategies/trials/endpoints or unread external materials.
Referenced methods: M08 Table 8.2.a, M04 §4.6.3; custom application; M04 §4.5–4.6 material-collection/selection principles; separation of access/reading and hyperlink conventions are custom design; M04 §4.5, §4.6.3; limits on current material conversion reflect the review scope and custom design

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N21 · Multiple outcomes, hierarchy and time points

Current findings: 5% is a secondary outcome distinct from mean weight. Success at multiple time points, blood-pressure/glucose/other outcomes or independent replication is not newly created.
Verification status: Partly verified
Materials actually read: Summary read; external material unread
Why unverified: Only the relevant information in the preserved summary is recorded; detailed originals remain unread and existing content review incomplete. Complete lists of secondary outcomes/time points, adjustment, hierarchy and analysis/reporting changes remain unverified. Existing content review remains incomplete.
Reason for missing information: Complete lists of secondary outcomes/time points, adjustment, hierarchy and analysis/reporting changes remain unverified.
Required materials and conditions: Multiplicity in testing responders and other time points/endpoints
Materials to obtain first: Complete results, SAP and hierarchy/multiplicity materials
Further research: A proposed study separating primary endpoints from secondary proportions and other outcomes; no new investigation, calculation or trial was performed.
Remaining uncertainty: This record links preserved-summary statements; it does not establish external-paper comparison, a new efficacy verdict or completed content review.
Conditions for verification: Corresponding original materials and analysis scope for multiplicity in testing responders and other time points/endpoints must be available and unverified matters distinguishable. Preserved wording is linked here; existing content review remains incomplete.
Why this condition is needed: An applied item distinguishing multiplicity in testing responders and other time points/endpoints to connect the selected question’s needed materials with current materials.
Application exceptions: Limited to the preserved summary’s selected strategy/population/endpoint/period. It does not replace numbers for other strategies/trials/endpoints or unread external materials.
Referenced methods: M08 Table 8.2.a, M04 §4.6.3; own application; M04 §4.6.1–4.6.2 on distinguishing studies from reports; cohort/outcome linkage is independently applied; M03 §3.2.4, M15 §15.3.1–15.3.3; question-specific outcome adaptation is independently designed

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N22 · Thresholds, importance and disease events

Current findings: The manuscript records no declared prespecified success threshold or externally validated minimum clinically important difference. The secondary 5% threshold is not repurposed as a trial-success boundary or reductions in blood pressure/glucose/disease events.
Verification status: Partly verified
Materials actually read: Summary read; external material unread
Why unverified: Only the relevant information in the preserved summary is recorded; detailed originals remain unread and existing content review incomplete. Evidence for threshold importance, advance success definitions and patient-important clinical/long-term outcomes remain unverified. Existing content review remains incomplete.
Reason for missing information: Evidence for threshold importance, advance success definitions and patient-important clinical/long-term outcomes remain unverified.
Required materials and conditions: Distinction between 5% response, advance success/importance criteria and clinical outcomes
Materials to obtain first: Threshold/importance criteria and clinical-outcome/follow-up materials
Further research: A proposed follow-up study distinguishing responders from clinical outcomes; no new investigation, calculation or trial was performed.
Remaining uncertainty: This record links preserved-summary statements; it does not establish external-paper comparison, a new efficacy verdict or completed content review.
Conditions for verification: Corresponding original materials and analysis scope for distinction between 5% response, advance success/importance criteria and clinical outcomes must be available and unverified matters distinguishable. Preserved wording is linked here; existing content review remains incomplete.
Why this condition is needed: An applied item distinguishing distinction between 5% response, advance success/importance criteria and clinical outcomes to connect the selected question’s needed materials with current materials.
Application exceptions: Limited to the preserved summary’s selected strategy/population/endpoint/period. It does not replace numbers for other strategies/trials/endpoints or unread external materials.
Referenced methods: M15 §15.3.1–15.3.3; custom application; M03 §3.2.4; custom extension boundary; M08 Table 8.2.a, M04 §4.6.3; custom application

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N23 · Concurrent management, medication and lifestyle

Current findings: This bundled trial involved baseline conditions and clinician counseling. Absence of medication/diet/activity/contact differences or effects on attaining 5% loss is not assumed.
Verification status: Unverified
Materials actually read: Summary read; external material unread
Why unverified: Information currently needed is unverified in the preserved summary. Group-specific concurrent management/medication changes, lifestyle, additional support and their analyses remain unverified. Existing content review remains incomplete.
Reason for missing information: Group-specific concurrent management/medication changes, lifestyle, additional support and their analyses remain unverified.
Required materials and conditions: Concurrent conditions/medication, lifestyle/clinical exposure and responder outcomes
Materials to obtain first: Concurrent-exposure, lifestyle/condition-management and analysis materials
Further research: A proposed follow-up study distinguishing concurrent management from responder outcomes; no new investigation, calculation or trial was performed.
Remaining uncertainty: This record links preserved-summary statements; it does not establish external-paper comparison, a new efficacy verdict or completed content review.
Conditions for verification: Corresponding original materials and analysis scope for concurrent conditions/medication, lifestyle/clinical exposure and responder outcomes must be available and unverified matters distinguishable. Preserved wording is linked here; existing content review remains incomplete.
Why this condition is needed: An applied item distinguishing concurrent conditions/medication, lifestyle/clinical exposure and responder outcomes to connect the selected question’s needed materials with current materials.
Application exceptions: Limited to the preserved summary’s selected strategy/population/endpoint/period. It does not replace numbers for other strategies/trials/endpoints or unread external materials.
Referenced methods: M03 §3.2.3, M08 §8.2.2–8.2.3; own application; M03 §3.2.2–3.2.3; reverse-direction labels and test adaptations are our own design

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N24 · NIH public support

Current findings: NIH NIDDK R01DK093829 provided support. This is not used as absence of all commercial/author relationships or new independence certification.
Verification status: Partly verified
Materials actually read: Summary read; external material unread
Why unverified: Only the relevant information in the preserved summary is recorded; detailed originals remain unread and existing content review incomplete. Funder/researcher roles, agreements, data/publication rights and complete disclosures remain unread. Existing content review remains incomplete.
Reason for missing information: Funder/researcher roles, agreements, data/publication rights and complete disclosures remain unread.
Required materials and conditions: Distinction between funder/grant, support roles and independence
Materials to obtain first: Funding, support-role and agreement disclosures
Further research: Proposed follow-up trial disclosing support/research roles; no new investigation, calculation or trial was performed in this production.
Remaining uncertainty: This record links preserved-summary statements; it does not establish external-paper comparison, a new efficacy verdict or completed content review.
Conditions for verification: Corresponding original materials and analysis scope for distinction between funder/grant, support roles and independence must be available and unverified matters distinguishable. Preserved wording is linked here; existing content review remains incomplete.
Why this condition is needed: An applied item distinguishing distinction between funder/grant, support roles and independence to connect the selected question’s needed materials with current materials.
Application exceptions: Limited to the preserved summary’s selected strategy/population/endpoint/period. It does not replace numbers for other strategies/trials/endpoints or unread external materials.
Referenced methods: Chamgap's own conditions for independence and attribution. The official methodological sections used in this example do not validate every detail of these items.

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N25 · Non-reporting of support in the pivotal paper

Current findings: The manuscript states that commercial sponsorship, donated scales, outsourced analysis, medical writing and publication-fee support were not reported in the pivotal paper. Non-reporting is not judged as actual absence of support.
Verification status: Partly verified
Materials actually read: Summary read; external material unread
Why unverified: Only the relevant information in the preserved summary is recorded; detailed originals remain unread and existing content review incomplete. Actual presence/scope of each support category, agreements, analysis/writing roles and original disclosures remain unread. Existing content review remains incomplete.
Reason for missing information: Actual presence/scope of each support category, agreements, analysis/writing roles and original disclosures remain unread.
Required materials and conditions: Category-specific scope of commercial, in-kind, outsourced-analysis/writing and publication support
Materials to obtain first: Commercial/in-kind, analysis and writing/publication support disclosures
Further research: A proposed study disclosing support categories distinctly; no new investigation, calculation or trial was performed.
Remaining uncertainty: This record links preserved-summary statements; it does not establish external-paper comparison, a new efficacy verdict or completed content review.
Conditions for verification: Corresponding original materials and analysis scope for category-specific scope of commercial, in-kind, outsourced-analysis/writing and publication support must be available and unverified matters distinguishable. Preserved wording is linked here; existing content review remains incomplete.
Why this condition is needed: An applied item distinguishing category-specific scope of commercial, in-kind, outsourced-analysis/writing and publication support to connect the selected question’s needed materials with current materials.
Application exceptions: Limited to the preserved summary’s selected strategy/population/endpoint/period. It does not replace numbers for other strategies/trials/endpoints or unread external materials.
Referenced methods: Chamgap independence/attribution conditions. The referenced official method sections do not certify every detail of these items; Data collection/selection principles in M04 §4.5–4.6; Access/reading separation and hyperlink rules are Chamgap design

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N26 · Later author relationships and disclosure timing

Current findings: The original record places later-paper disclosures of Gary Bennett’s WW advisory role and equity in Coeus Health after the pivotal trial. Funding/COI during that trial are not retrospectively established.
Verification status: Partly verified
Materials actually read: Summary read; external material unread
Why unverified: Only the relevant information in the preserved summary is recorded; detailed originals remain unread and existing content review incomplete. Specific later bibliography, disclosure timing, relationships/agreements during the original trial and complete COI remain unlinked/unread. Existing content review remains incomplete.
Reason for missing information: Specific later bibliography, disclosure timing, relationships/agreements during the original trial and complete COI remain unlinked/unread.
Required materials and conditions: Distinction between later WW/Coeus disclosures and original-trial timing/roles
Materials to obtain first: Later disclosures, dates and relationship materials with original-trial statements
Further research: A proposed study distinguishing relationship/support attribution by period; no new investigation, calculation or trial was performed.
Remaining uncertainty: This record links preserved-summary statements; it does not establish external-paper comparison, a new efficacy verdict or completed content review.
Conditions for verification: Corresponding original materials and analysis scope for distinction between later WW/Coeus disclosures and original-trial timing/roles must be available and unverified matters distinguishable. Preserved wording is linked here; existing content review remains incomplete.
Why this condition is needed: An applied item distinguishing distinction between later WW/Coeus disclosures and original-trial timing/roles to connect the selected question’s needed materials with current materials.
Application exceptions: Limited to the preserved summary’s selected strategy/population/endpoint/period. It does not replace numbers for other strategies/trials/endpoints or unread external materials.
Referenced methods: Chamgap’s custom independence/attribution conditions. The official methodology sections used in this pilot do not guarantee all these detailed items; M04 §4.5, §4.6.3; current conversion limits reflect review scope and custom design; M04 §4.6.1–4.6.2 distinction between studies and reports; cohort/outcome linkage is custom application

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N27 · References to null results from other programs

Current findings: References to null trials of app-only or low-intensity technology support limit generalization because composition/intensity differ. Those reports are not newly created or combined as direct refutations or independent replications of Track’s responder result.
Verification status: Partly verified
Materials actually read: Summary read; external material unread
Why unverified: Only the relevant information in the preserved summary is recorded; detailed originals remain unread and existing content review incomplete. Specific bibliography, populations, proportions/endpoints, denominators and results for other programs remain unlinked. Existing content review remains incomplete.
Reason for missing information: Specific bibliography, populations, proportions/endpoints, denominators and results for other programs remain unlinked.
Required materials and conditions: Directness of Track’s bundle versus app-only/low-intensity programs
Materials to obtain first: Other-program originals and composition/endpoint relationships
Further research: A proposed direct follow-up comparison matching composition and intensity; no new investigation, calculation or trial was performed.
Remaining uncertainty: This record links preserved-summary statements; it does not establish external-paper comparison, a new efficacy verdict or completed content review.
Conditions for verification: Corresponding original materials and analysis scope for directness of Track’s bundle versus app-only/low-intensity programs must be available and unverified matters distinguishable. Preserved wording is linked here; existing content review remains incomplete.
Why this condition is needed: An applied item distinguishing directness of Track’s bundle versus app-only/low-intensity programs to connect the selected question’s needed materials with current materials.
Application exceptions: Limited to the preserved summary’s selected strategy/population/endpoint/period. It does not replace numbers for other strategies/trials/endpoints or unread external materials.
Referenced methods: M04 §4.6.3, M15 §15.3.1–15.3.3; status separation is custom design; M04 §4.6.1–4.6.2 distinction between studies and reports; cohort/outcome linkage is custom application; M03 §3.2.2–3.2.3; reverse-direction labeling and test adaptation are custom design

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N28 · Same report, sibling sheets and independence

Current findings: The 5% and mean sheets share the same Bennett2018 Track trial of 351 participants. Groups, time points, thresholds, bibliography/registration and sibling sheets are not added as new independent trials or participants.
Verification status: Partly verified
Materials actually read: Summary read; external material unread
Why unverified: Only the relevant information in the preserved summary is recorded; detailed originals remain unread and existing content review incomplete. Independent reproduction under the same bundle/responder conditions and unique clinical totals are not established. Existing content review remains incomplete.
Reason for missing information: Independent reproduction under the same bundle/responder conditions and unique clinical totals are not established.
Required materials and conditions: Mean/responder, report/registration and group/time-point relationships
Materials to obtain first: Report/cohort relationships and originals of separate independent trials
Further research: A proposed independent follow-up comparison specifying the same secondary threshold; no new investigation, calculation or trial was performed.
Remaining uncertainty: This record links preserved-summary statements; it does not establish external-paper comparison, a new efficacy verdict or completed content review.
Conditions for verification: Corresponding original materials and analysis scope for mean/responder, report/registration and group/time-point relationships must be available and unverified matters distinguishable. Preserved wording is linked here; existing content review remains incomplete.
Why this condition is needed: An applied item distinguishing mean/responder, report/registration and group/time-point relationships to connect the selected question’s needed materials with current materials.
Application exceptions: Limited to the preserved summary’s selected strategy/population/endpoint/period. It does not replace numbers for other strategies/trials/endpoints or unread external materials.
Referenced methods: Study/report distinction in M04 §4.6.1–4.6.2; Cohort/outcome linkage is Chamgap application; M04 §4.6.1–4.6.2 and M15 §15.3.1; Chamgap application

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N29 · Persistence and applicability to other compositions/populations

Current findings: The 12-month bundled trial’s responder result is not extended to all apps/products, other populations, maintenance after stopping the intervention or disease treatment. No new recommendations or weight-loss instructions are created.
Verification status: Partly verified
Materials actually read: Summary read; external material unread
Why unverified: Only the relevant information in the preserved summary is recorded; detailed originals remain unread and existing content review incomplete. Long-term/discontinuation follow-up, other compositions/populations and direct single-component comparisons remain unverified. Existing content review remains incomplete.
Reason for missing information: Long-term/discontinuation follow-up, other compositions/populations and direct single-component comparisons remain unverified.
Required materials and conditions: Distinction between Track responder results and long-term/stand-alone-app/other-population effects
Materials to obtain first: Long-term follow-up and direct comparisons by composition/population
Further research: A proposed study distinguishing threshold attainment from persistence/applicability; no new investigation, calculation or trial was performed.
Remaining uncertainty: This record links preserved-summary statements; it does not establish external-paper comparison, a new efficacy verdict or completed content review.
Conditions for verification: Corresponding original materials and analysis scope for distinction between Track responder results and long-term/stand-alone-app/other-population effects must be available and unverified matters distinguishable. Preserved wording is linked here; existing content review remains incomplete.
Why this condition is needed: An applied item distinguishing distinction between Track responder results and long-term/stand-alone-app/other-population effects to connect the selected question’s needed materials with current materials.
Application exceptions: Limited to the preserved summary’s selected strategy/population/endpoint/period. It does not replace numbers for other strategies/trials/endpoints or unread external materials.
Referenced methods: M03 §3.2.1–3.2.4; dose, persistence and effect-modification details are custom design; M03 §3.2.4; custom extension boundary; M03 §3.2.2–3.2.3; reverse-direction labeling and test adaptation are custom design

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N30 · Unknown safety and collection gaps

Current findings: The original record states that parent safety is unknown and adverse events from a prespecified safety endpoint were not systematically presented in the pivotal paper. Attaining 5% loss is not converted into absence of harm or treatment safety.
Verification status: Partly verified
Materials actually read: Summary read; external material unread
Why unverified: Only the relevant information in the preserved summary is recorded; detailed originals remain unread and existing content review incomplete. Adverse-event collection/adjudication, group-specific types/frequencies/denominators, discontinuation and vulnerable-population/long-term harms remain unverified. Existing content review remains incomplete.
Reason for missing information: Adverse-event collection/adjudication, group-specific types/frequencies/denominators, discontinuation and vulnerable-population/long-term harms remain unverified.
Required materials and conditions: Prespecification, collection/denominators and follow-up for adverse events
Materials to obtain first: Safety plans, adverse events and discontinuation/long-term follow-up
Further research: A proposed follow-up study specifying harm collection and follow-up; no new investigation, calculation or trial was performed.
Remaining uncertainty: This record links preserved-summary statements; it does not establish external-paper comparison, a new efficacy verdict or completed content review.
Conditions for verification: Corresponding original materials and analysis scope for prespecification, collection/denominators and follow-up for adverse events must be available and unverified matters distinguishable. Preserved wording is linked here; existing content review remains incomplete.
Why this condition is needed: An applied item distinguishing prespecification, collection/denominators and follow-up for adverse events to connect the selected question’s needed materials with current materials.
Application exceptions: Supplements safety-data gaps for the selected subclaim. Mean weight, 5% responder results and parent caution wording are not used to judge safety or generate harm incidence or new use instructions.
Referenced methods: M19 §19.1.2–19.2.4; detailed distinctions are Chamgap’s own design; M19 §19.1.2–19.2.4; Chamgap application; M19 §19.1.2–19.2.4; Chamgap application; M19 §19.1.2–19.2.4; Chamgap application

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N31 · Parent/subclaim, Korean/English, corrections and history

Current findings: Parent C56, B/S/R1/I2/E+/B0, unrecorded precision, three false flags, empty override reasons and subclaim grade C/note are preserved. Korean/English text, 2026-08-26, empty corrections/deliberation and historical cross-checking are not inherited as current review or a subclaim score.
Verification status: Partly verified
Materials actually read: Summary read; external material unread
Why unverified: Only the relevant information in the preserved summary is recorded; detailed originals remain unread and existing content review incomplete. Absent subclaim score/status/axes are not filled with parent values, and no new certification is created. Existing content review remains incomplete.
Reason for missing information: Absent subclaim score/status/axes are not filled with parent values, and no new certification is created.
Required materials and conditions: Separate preservation of original values/axes, reference dates and verification narratives
Materials to obtain first: Original corrections, versions and user correction comments
Further research: Proposed research distinguishing original values/history from new-update scope; no new investigation, calculation or trial was performed in this production.
Remaining uncertainty: This record links preserved-summary statements; it does not establish external-paper comparison, a new efficacy verdict or completed content review.
Conditions for verification: Corresponding original materials and analysis scope for separate preservation of original values/axes, reference dates and verification narratives must be available and unverified matters distinguishable. Preserved wording is linked here; existing content review remains incomplete.
Why this condition is needed: An applied item distinguishing separate preservation of original values/axes, reference dates and verification narratives to connect the selected question’s needed materials with current materials.
Application exceptions: Limited to the preserved summary’s selected strategy/population/endpoint/period. It does not replace numbers for other strategies/trials/endpoints or unread external materials.
Referenced methods: M04 §4.5, §4.6.3; limits of this material conversion follow the review scope and internal design; M03 §3.1, §3.2.1–3.2.4 question-clarification principles; detailed separation rules are internally designed

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N32 · Summary reading, external links and updates

Current findings: The full preserved JSON summary and bibliography were used for production, and links are retained. Papers, registration, protocol, SAP and original later disclosures/support materials remain unread with no access attempt; links were not tested.
Verification status: Partly verified
Materials actually read: Summary read; external material unread
Why unverified: Only the relevant information in the preserved summary is recorded; detailed originals remain unread and existing content review incomplete. External originals, exact responder denominators/models and actual accessibility remain unverified. Existing content review remains incomplete.
Reason for missing information: External originals, exact responder denominators/models and actual accessibility remain unverified.
Required materials and conditions: Actually read scope and access status of external materials
Materials to obtain first: Originals, registration, protocol, SAP, support/COI materials or user comments
Further research: A proposed study updating acquisition, timing and scope of materials separately; no new investigation, calculation or trial was performed.
Remaining uncertainty: This record links preserved-summary statements; it does not establish external-paper comparison, a new efficacy verdict or completed content review.
Conditions for verification: Corresponding original materials and analysis scope for actually read scope and access status of external materials must be available and unverified matters distinguishable. Preserved wording is linked here; existing content review remains incomplete.
Why this condition is needed: An applied item distinguishing actually read scope and access status of external materials to connect the selected question’s needed materials with current materials.
Application exceptions: Limited to the preserved summary’s selected strategy/population/endpoint/period. It does not replace numbers for other strategies/trials/endpoints or unread external materials.
Referenced methods: M04 §4.5–4.6 material collection/selection principles; acquisition/reading separation and hyperlink specifications are internally designed; M04 §4.5, §4.6.3; limits of this material conversion follow the review scope and internal design

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