Didgeridoo training × daytime sleepiness in moderate OSA

Required evidence, verification status and materials actually read
Item	AVerification status	BReading scope	CReview item	DCurrent findings	EWhy unverified	FRequired materials and conditions	GFurther research
1	Partly verified	Full text not readStored summary read	N01 · Evidence conditionWhich daytime-sleepiness claim is examined?Required	The selected claim is reduced daytime sleepiness in moderate OSA. Original grade C and the ESS between-group difference of −3.0 points in its note are retained. Subclaim score, status and axes are absent; parent C50 does not fill a subclaim score. S01 S02	The selected claim, parent material and reports are distinguished and transferred from the stored summary. Detailed original material is unverified and review of existing content remains incomplete. This does not establish completed clinical review or certification.	Selected sleepiness claim, note/grade and parent verdict	Material needed: Separate subclaim score, status and axes are absent from the original. The selected claim and parent verdict must be distinguished. This records needed materials; no new research was executed.
2	Partly verified	Full text not readStored summary read	N02 · Evidence conditionWhich adults with moderate OSA were studied?Required	The original population is 25 adults with moderate OSA, BMI below 30 and AHI 15–30/h. This is not extended to every BMI, severity, age or sleep-disorder population. S01	The selected claim, parent material and reports are distinguished and transferred from the stored summary. Detailed original material is unverified and review of existing content remains incomplete. This does not establish completed clinical review or certification.	Eligibility, baseline characteristics, diagnosis and arm denominators	Material needed: Exact age, sex, baseline ESS, diagnostic procedures and arm allocation denominators are unverified. This records needed materials; no new research was executed.
3	Partly verified	Full text not readStored summary read	N03 · Evidence conditionWhich program was studied?Required	The original records a structured didgeridoo lesson/home-practice program. This is not changed into a particular instrument-brand effect or an equivalent effect from all playing/breathing training. S01	The selected claim, parent material and reports are distinguished and transferred from the stored summary. Detailed original material is unverified and review of existing content remains incomplete. This does not establish completed clinical review or certification.	Lessons, home practice, developer and intervention specification	Material needed: Lesson components, contact, individual actual practice and generalizable components are unverified. This records needed materials; no new research was executed.
4	Partly verified	Full text not readStored summary read	N04 · Evidence conditionDoes average practice describe an individual procedure?Required	Mean 5.9 days weekly, 25.3 minutes per session and approximately 25 minutes in the original intervention name describe study exposure. They are not treated as equal exposure for everyone or recommended procedures, and totals are not newly converted. S01	The selected claim, parent material and reports are distinguished and transferred from the stored summary. Detailed original material is unverified and review of existing content remains incomplete. This does not establish completed clinical review or certification.	Planned exposure, mean actual exposure, distribution and adherence	Material needed: Planned exposure, individual distributions, discontinuation, adherence assessment and ESS by exposure are unverified. This records needed materials; no new research was executed.
5	Partly verified	Full text not readStored summary read	N05 · Evidence conditionWhat does the wait-list comparison establish?Required	Paper S01 is a randomized wait-list comparison. It is not a direct comparison with standard OSA therapy, another instrument or equal-contact sham. S01	The selected claim, parent material and reports are distinguished and transferred from the stored summary. Detailed original material is unverified and review of existing content remains incomplete. This does not establish completed clinical review or certification.	Control care, contact, expectations and concurrent treatment	Material needed: Detailed wait-list care, contact, expectation differences and concurrent treatment are unverified. This records needed materials; no new research was executed.
6	Partly verified	Full text not readStored summary read	N06 · Evidence conditionAre randomization and concealment detailed?Required	The S01 design and stored report record random allocation. The summary does not establish sequence generation, allocation concealment or processes before/after recruitment. S01	The selected claim, parent material and reports are distinguished and transferred from the stored summary. Detailed original material is unverified and review of existing content remains incomplete. This does not establish completed clinical review or certification.	Allocation sequence, concealment and recruitment processes	Material needed: Sequence generation, concealment, responsible staff and recruitment/allocation processes are unverified. This records needed materials; no new research was executed.
7	Partly verified	Full text not readStored summary read	N07 · Evidence conditionIs unblinded symptom assessment distinguished?Required	The stored report states that participants knew their intervention and identifies unblinded subjective symptom assessment as a limitation. Objective AHI does not substitute for ESS masking or control of expectation effects. S01	The selected claim, parent material and reports are distinguished and transferred from the stored summary. Detailed original material is unverified and review of existing content remains incomplete. This does not establish completed clinical review or certification.	Participant, assessor/analyst masking and expectation differences	Material needed: Assessor/analyst masking, contact/expectation differences and their control are unverified. This records needed materials; no new research was executed.
8	Partly verified	Full text not readStored summary read	N08 · Evidence conditionWhat did ESS assess and when?Required	The S01 main endpoint is the four-month Epworth Sleepiness Scale (ESS) score. AHI/h, PSQI and bed-partner disturbance are different measures. S01	The selected claim, parent material and reports are distinguished and transferred from the stored summary. Detailed original material is unverified and review of existing content remains incomplete. This does not establish completed clinical review or certification.	Scale, assessment window, method and units	Material needed: Scale administration, recall period, assessment timing, standardization and baseline distributions are unverified. This records needed materials; no new research was executed.
9	Partly verified	Full text not readStored summary read	N09 · Evidence conditionWhat is the original ESS difference, CI and P value?Required	The ESS between-group difference of −3.0 points (95% CI −5.7 to −0.3, P=.03) is preserved. It is not transferred into within-arm change, treatment-replacement differences or cure rates. S01	The selected claim, parent material and reports are distinguished and transferred from the stored summary. Detailed original material is unverified and review of existing content remains incomplete. This does not establish completed clinical review or certification.	Comparative estimate, units, denominators and model	Material needed: Original arm values, exact analysis denominators, model, baseline adjustment and outcome-hierarchy details are unverified. This records needed materials; no new research was executed.
10	Unverified	Full text not readStored summary read	N10 · Evidence conditionAre ESS importance and individual distributions verified?Required	The stored report describes a symptom signal from one small trial. −3.0 points and statistical significance alone do not establish perceived or clinically important improvement for every participant. S01	The selected claim, parent material and reports are distinguished and transferred from the stored summary. Detailed original material is unverified and review of existing content remains incomplete. This does not establish completed clinical review or certification.	Relevance thresholds, individual changes and uncertainty	Material needed: Prior relevance thresholds, individual distributions, response definitions and persistence are unverified. This records needed materials; no new research was executed.
11	Partly verified	Full text not readStored summary read	N11 · Evidence conditionDid effects persist after four months?Required	The original study assessed four months. Original statements that long-term complication prevention and standard-treatment replacement were not tested are preserved separately. S01	The selected claim, parent material and reports are distinguished and transferred from the stored summary. Detailed original material is unverified and review of existing content remains incomplete. This does not establish completed clinical review or certification.	Assessment duration, intervention cessation and long-term follow-up	Material needed: ESS persistence beyond four months, post-intervention changes and long-term clinical outcomes have no linked material. This records needed materials; no new research was executed.
12	Partly verified	Full text not readStored summary read	N12 · Evidence conditionIs AHI a separate result from ESS?Required	The AHI between-group difference of −6.2/h (−12.3 to −0.1, P=.05) is a separate sleep-study result. Its same-direction original signal is preserved without transfer to ESS effects/scores, cure or equivalence to standard therapy. S01	The selected claim, parent material and reports are distinguished and transferred from the stored summary. Detailed original material is unverified and review of existing content remains incomplete. This does not establish completed clinical review or certification.	Distinguishing ESS/AHI definitions, results and units	Material needed: Sleep-study methods, AHI calculation, condition-specific denominators and exact prior analysis plans are unverified. This records needed materials; no new research was executed.
13	Partly verified	Full text not readStored summary read	N13 · Evidence conditionIs the null PSQI result also retained?Required	PSQI −0.7 points (−2.1 to 0.6, P=.27) is described as null in the original. The sleepiness signal is not transferred to overall sleep-quality improvement, and nonsignificance does not become an exact zero effect. S01	The selected claim, parent material and reports are distinguished and transferred from the stored summary. Detailed original material is unverified and review of existing content remains incomplete. This does not establish completed clinical review or certification.	Endpoint-specific effects, units and uncertainty	Material needed: PSQI procedures, denominators, model and prespecified hierarchy are unverified. This records needed materials; no new research was executed.
14	Partly verified	Full text not readStored summary read	N14 · Evidence conditionAre the bed-partner respondent and endpoint distinguished?Required	The original describes a −2.8-point improvement in bed-partner sleep disturbance as subjective assessment. It is not transferred to patient ESS, objective AHI or direct replication in an independent trial. S01	The selected claim, parent material and reports are distinguished and transferred from the stored summary. Detailed original material is unverified and review of existing content remains incomplete. This does not establish completed clinical review or certification.	Respondent, scale, endpoint and denominators	Material needed: Bed-partner denominators, scale, exact CIs/P values, masking and prior hierarchy are unverified. This records needed materials; no new research was executed.
15	Partly verified	Full text not readStored summary read	N15 · Evidence conditionDoes completion by everyone establish every analysis denominator?Required	The original records all 25 participants completing follow-up. This does not automatically fill arm n, complete ESS/AHI/PSQI analyses or ITT/PP status. S01	The selected claim, parent material and reports are distinguished and transferred from the stored summary. Detailed original material is unverified and review of existing content remains incomplete. This does not establish completed clinical review or certification.	Allocation, completion, endpoint analyses and missingness	Material needed: Arm allocation, endpoint analysis denominators, missingness, ITT/PP and exclusion reasons are unverified. This records needed materials; no new research was executed.
16	Unverified	Full text not readStored summary read	N16 · Evidence conditionAre concurrent treatment, weight and lifestyle changes verified?Required	The comparison is lessons/home practice versus waiting. The summary is not extended to certify control or absence of concurrent OSA therapy, weight changes or lifestyle changes. S01	The selected claim, parent material and reports are distinguished and transferred from the stored summary. Detailed original material is unverified and review of existing content remains incomplete. This does not establish completed clinical review or certification.	Arm-specific concurrent care, exposure and adjustment	Material needed: Concurrent therapy, weight/activity changes, medication, baseline adjustment and adherence are unverified. This records needed materials; no new research was executed.
17	Partly verified	Full text not readStored summary read	N17 · Evidence conditionWhen was ISRCTN registration made?Required	The preserved registration is ISRCTN31571714; the original records registration after recruitment began. Its identifier/URL does not establish current registration reading or verification of prerecruitment registration. S01 S02	The selected claim, parent material and reports are distinguished and transferred from the stored summary. Detailed original material is unverified and review of existing content remains incomplete. This does not establish completed clinical review or certification.	Registration identity, recruitment/registration timing and original records	Material needed: Exact recruitment/registration dates, original registration and change-history details remain unread. This records needed materials; no new research was executed.
18	Partly verified	Full text not readStored summary read	N18 · Evidence conditionDoes an ESS main endpoint establish the complete prior plan?Required	The original evidence item records four-month ESS as the main endpoint; historical grading describes separation of ESS/AHI/PSQI. In the retrospective-registration context, this is not converted into verified prerecruitment hierarchy or a completely reviewed SAP. S01 S02	The selected claim, parent material and reports are distinguished and transferred from the stored summary. Detailed original material is unverified and review of existing content remains incomplete. This does not establish completed clinical review or certification.	Separating main-endpoint wording, registration, protocol and SAP	Material needed: Prerecruitment ESS hierarchy, protocol, SAP, change history and analysis plans are unverified. This records needed materials; no new research was executed.
19	Unverified	Full text not readStored summary read	N19 · Evidence conditionAre multiple endpoints and test models distinguished?Required	ESS, AHI, PSQI and subjective bed-partner assessment are different results. Some significant results are not extended to success of all endpoints or prior multiplicity adjustment. S01	The selected claim, parent material and reports are distinguished and transferred from the stored summary. Detailed original material is unverified and review of existing content remains incomplete. This does not establish completed clinical review or certification.	All endpoints, tests, adjustment and multiplicity	Material needed: Test direction, exact models, covariates, multiplicity and prior plans for additional endpoints are unverified. This records needed materials; no new research was executed.
20	Partly verified	Full text not readStored summary read	N20 · Evidence conditionAre the paper and registration separate trials?Required	The S01 Puhan 2006 paper and S02 ISRCTN31571714 registration are preserved links to the same 25-person four-month trial. Registration is not counted as another sleepiness-effect report, new participants or an independent trial. S01 S02	The selected claim, parent material and reports are distinguished and transferred from the stored summary. Detailed original material is unverified and review of existing content remains incomplete. This does not establish completed clinical review or certification.	Reports, registration, trial family and population links	Material needed: Detailed original/registration plans and correspondence between analyses remain externally unread. This records needed materials; no new research was executed.
21	Unverified	Full text not readStored summary read	N21 · Evidence conditionWas the sleepiness effect independently replicated?Required	The stored report states that independent replication was absent. Multiple endpoints, paper/registration and two subclaim sheets from one trial do not become independent replication. S01 S02	The selected claim, parent material and reports are distinguished and transferred from the stored summary. Detailed original material is unverified and review of existing content remains incomplete. This does not establish completed clinical review or certification.	Separate trials with the same population/intervention/comparator	Material needed: Separate replication under the same conditions and actual trial-family independence are unverified. This records needed materials; no new research was executed.
22	Unverified	Full text not readStored summary read	N22 · Evidence conditionDoes this apply to other BMIs, severities or ages?Required	The direct population is selected adults with BMI below 30 and AHI 15–30/h. The same effects are not generalized to other severities, BMIs, ages or diseases. S01	The selected claim, parent material and reports are distinguished and transferred from the stored summary. Detailed original material is unverified and review of existing content remains incomplete. This does not establish completed clinical review or certification.	Direct population-specific material and subgroup plans	Material needed: Population-specific ESS, AHI, safety and prior subgroup plans have no linked material. This records needed materials; no new research was executed.
23	Partly verified	Full text not readStored summary read	N23 · Evidence conditionDo sleepiness/AHI signals establish replacement of standard therapy?Required	The parent report describes a wait-list signal and states that noninferiority/replacement versus CPAP or oral appliances was not tested. Sleepiness results do not establish equal standard-treatment effects, cure or grounds to stop treatment. S01 S02	The selected claim, parent material and reports are distinguished and transferred from the stored summary. Detailed original material is unverified and review of existing content remains incomplete. This does not establish completed clinical review or certification.	Direct standard-treatment comparisons and clinical outcomes	Material needed: Direct standard-treatment comparisons, noninferiority and long-term clinical outcomes have no linked material. This records needed materials; no new research was executed.
24	Partly verified	Full text not readStored summary read	N24 · Evidence conditionAre funding, the developer-instructor and conflicts distinguished?Required	Original funding records Zurich Lung Association/clinical support and a training developer-instructor among the authors. This is not converted into complete conflict verification or independence certification. S01	The selected claim, parent material and reports are distinguished and transferred from the stored summary. Detailed original material is unverified and review of existing content remains incomplete. This does not establish completed clinical review or certification.	Original support, product, employee/developer and COI records	Material needed: Funding roles, equipment/instrument support, developer-instructor roles, employee authors, COI and analysis/reporting involvement are unverified. This records needed materials; no new research was executed.
25	Partly verified	Full text not readStored summary read	N25 · Evidence conditionWhat was reported about safety and sample-size limits?Supplementary	The original parent safety label is Good; no unexpected/adverse events were reported in 25 people over four months. This is not extended to absence of rare harms, long-term safety or safety of stopping established treatment. S01	The selected claim, parent material and reports are distinguished and transferred from the stored summary. Detailed original material is unverified and review of existing content remains incomplete. This does not establish completed clinical review or certification.	Harm collection, exposure, arm denominators and follow-up	Material needed: Collection methods, event definitions, arm denominators, rare/long-term harms and treatment-cessation material are unverified. This records needed materials; no new research was executed.
26	Partly verified	Full text not readStored summary read	N26 · Evidence conditionAre parent values, subclaim grade and the evidence date separated?Required	Parent C50, B/P/R1/I1/E+/B2/CX, four false flags, empty override and subclaim C/note are preserved. Original bilingual wording, 2026-09-07, empty corrections array and empty deliberation string are not inherited as the current review date or a subclaim score. S01 S02	The selected claim, parent material and reports are distinguished and transferred from the stored summary. Detailed original material is unverified and review of existing content remains incomplete. This does not establish completed clinical review or certification.	Parent/subclaim original values and historical dates	Material needed: Subclaim score, status and axes are absent from the original. New corrections and external original-text comparisons were not performed. This records needed materials; no new research was executed.
27	Partly verified	Full text not readStored summary read	N27 · Evidence conditionAre historical checks the current reading?Required	Original primary-trial, ISRCTN and effect-size verification is preserved as historical wording. Stored summaries/bibliography were used here; original papers, registration, protocols, SAPs and COI remain unread without access attempts. S01 S02	The selected claim, parent material and reports are distinguished and transferred from the stored summary. Detailed original material is unverified and review of existing content remains incomplete. This does not establish completed clinical review or certification.	Historical review statements, summary use and external access	Material needed: Historical-check details, current external-original acquisition/reading and content review remain incomplete. This records needed materials; no new research was executed.
28	Partly verified	Full text not readStored summary read	N28 · Evidence conditionWhich materials would trigger an update?Required	Original paper/ISRCTN URLs are retained and actual reading is distinguished as summary read versus external material unread. URL presence alone does not raise verification status. S01 S02	The selected claim, parent material and reports are distinguished and transferred from the stored summary. Detailed original material is unverified and review of existing content remains incomplete. This does not establish completed clinical review or certification.	Linking summary reading, unread originals and needed material	Material needed: External-original acquisition, reading, URL verification and content review are needed. Complete pre-change originals, material/condition versions, separate application and change history must be retained. This records needed materials; no new research was executed.

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28 itemsWhat the statuses mean

Assessment scope

Stored-material review date: Not recorded
Original evidence cut-off: 2026-09-07
Scope actually checked: Existing review summaries and stored records of methodological application. Full papers, supplements, registrations, plans and original data were not read.
What the dates mean: This is the date the stored materials were checked, not the date of a new search of the clinical literature.
Population: The original records 25 adults with moderate obstructive sleep apnea (OSA), BMI below 30 and AHI 15–30/h, all completing follow-up. Age, sex, eligibility details, baseline ESS, arm allocation and endpoint analysis denominators are unverified. This is not generalized to all BMIs, severities or ages; completion by everyone does not fill complete analyses for every endpoint.
Ingredient, formulation and route: A structured didgeridoo lesson/home-practice program. This is not converted into a specific instrument-brand effect or equivalent effects from all playing/breathing training. Components, contact, individual actual practice and adherence are unverified. No new playing/breathing methods or procedures are created.
Dose: Original mean 5.9 days weekly, 25.3 minutes per session and approximately 25 minutes in the intervention name are preserved only as study exposure. Plans, individual distributions, discontinuation and adherence details are unverified. Means do not become identical exposure for everyone or a recommended schedule; total time, frequency and individual intensity are not newly converted.
Comparator: A four-month wait-list control. Contact, expectation differences and concurrent-treatment details are unverified. This is not converted into direct comparisons, equivalence or treatment-replacement effects versus standard CPAP, oral appliances, other instruments or equal-contact sham.
Measured outcome: The selected endpoint is four-month Epworth Sleepiness Scale (ESS), with between-group difference −3.0 points (95% CI −5.7 to −0.3, P=.03). AHI −6.2/h (−12.3 to −0.1, P=.05), null PSQI −0.7 points (−2.1 to 0.6, P=.27) and subjective bed-partner assessment −2.8 points are separate. Exact models, denominators and prerecruitment hierarchy are unverified. Units, respondents and endpoints are not mixed; no new effects, CIs or cure rates are created.
Duration: Original four-month assessment and completion by all 25 participants. Boundaries of unverified/untested later ESS persistence, post-intervention change, long-term complication prevention and standard-treatment replacement are retained. Short-term symptom/sleep-study results are not extended to long-term clinical outcomes or safety of stopping established treatment.
Questions outside this scope: Mixing ESS points, AHI/h, PSQI and bed-partner assessment as the same unit, respondent, endpoint or cure rate; Transferring an unblinded wait-list ESS signal into direct comparisons, equivalence, noninferiority or replacement effects versus CPAP/oral appliances; Filling arm n, every endpoint denominator or ITT from all 25 completing, or adding paper/registration/two subclaim sheets as independent trials/participants; Inheriting retrospective registration or original historical checks as prerecruitment plans, current external reading or completed clinical review; Extending parent C50, Good and axes into subclaim scores, all BMIs/severities, long-term clinical effects or safety; Creating new arithmetic, effects, CIs, hypothetical numbers, grades, independence certification, playing/breathing methods, training, treatment-replacement or procedure instructions

Evidence and sources

The links below lead to the sources. A link alone does not mean the original source was read or its latest publication status verified.

S01 · Puhan MA et al. BMJ 2006

PubMed

Material type: Randomized wait-list controlled trial
Materials actually read: Stored summaries read; original external papers, registration, protocols, SAPs and COI unread without access attempts
Findings recorded in the stored summary: ESS −3.0 points (−5.7 to −0.3); AHI −6.2/h (−12.3 to −0.1); PSQI null
Record level: Preserved original-paper result summary. Selected ESS points are distinguished from AHI/h, PSQI and subjective bed-partner assessment. Arm denominators, exact models and prerecruitment plans are unverified; wait-list results are not transferred to replacement of standard therapy.
Study overlap and independent replication: The S01 Puhan 2006 paper and S02 ISRCTN31571714 registration are preserved links to the same 25-person four-month didgeridoo lesson/home-practice versus wait-list trial. ESS, AHI, PSQI, bed-partner endpoints, two subclaim sheets and registration are not added as new independent trials, participants or replications. Detailed originals/registration remain externally unread; confirmed unique-trial, participant and independent-replication totals are unrecorded.

Public availability, access and reading status by material
Material	Public availability	Access status	Actually read	Notes
Stored existing review summary	Preserved copy of the complete parent-verdict stored summary	Stored summary	Summary read	Original PubMed URL, PMID 16377643, PMCID PMC1360393, DOI 10.1136/bmj.38705.470590.55 and same-trial ISRCTN31571714 link are preserved. Identifiers alone do not certify current reading, acquisition, prior plans or condition fulfillment, and new URLs are not inferred.
External paper	Original bibliographic link or needed material; external public availability/access status unverified	Unread; access not attempted	Not read	Original PubMed URL, PMID 16377643, PMCID PMC1360393, DOI 10.1136/bmj.38705.470590.55 and same-trial ISRCTN31571714 link are preserved. Identifiers alone do not certify current reading, acquisition, prior plans or condition fulfillment, and new URLs are not inferred.
Registration material	Original bibliographic link or needed material; external public availability/access status unverified	Unread; access not attempted	Not read	Original PubMed URL, PMID 16377643, PMCID PMC1360393, DOI 10.1136/bmj.38705.470590.55 and same-trial ISRCTN31571714 link are preserved. Identifiers alone do not certify current reading, acquisition, prior plans or condition fulfillment, and new URLs are not inferred.
Protocol	Original bibliographic link or needed material; external public availability/access status unverified	Unread; access not attempted	Not read	Original PubMed URL, PMID 16377643, PMCID PMC1360393, DOI 10.1136/bmj.38705.470590.55 and same-trial ISRCTN31571714 link are preserved. Identifiers alone do not certify current reading, acquisition, prior plans or condition fulfillment, and new URLs are not inferred.
Statistical analysis plan	Original bibliographic link or needed material; external public availability/access status unverified	Unread; access not attempted	Not read	Original PubMed URL, PMID 16377643, PMCID PMC1360393, DOI 10.1136/bmj.38705.470590.55 and same-trial ISRCTN31571714 link are preserved. Identifiers alone do not certify current reading, acquisition, prior plans or condition fulfillment, and new URLs are not inferred.
Funding, product-support and COI material	Original bibliographic link or needed material; external public availability/access status unverified	Unread; access not attempted	Not read	Original PubMed URL, PMID 16377643, PMCID PMC1360393, DOI 10.1136/bmj.38705.470590.55 and same-trial ISRCTN31571714 link are preserved. Identifiers alone do not certify current reading, acquisition, prior plans or condition fulfillment, and new URLs are not inferred.

S02 · ISRCTN31571714. Didgeridoo playing as alternative treatment for obstructive sleep apnoea syndrome.

Official source

Material type: Registration bibliography for the same trial; not a separate clinical-effect report
Materials actually read: Stored summaries read; original external papers, registration, protocols, SAPs and COI unread without access attempts
Findings recorded in the stored summary: The original citation historically states that registration timing and multiple-endpoint descriptions were checked. This does not establish current registration reading or newly verified clinical effects.
Record level: Historical verification wording in preserved registration bibliography, linked to the same trial. The original statement that registration followed recruitment is retained. Exact recruitment/registration dates, change history, protocol and SAP remain unread; no separate effects, CIs or independent trials are created.
Study overlap and independent replication: The S01 Puhan 2006 paper and S02 ISRCTN31571714 registration are preserved links to the same 25-person four-month didgeridoo lesson/home-practice versus wait-list trial. ESS, AHI, PSQI, bed-partner endpoints, two subclaim sheets and registration are not added as new independent trials, participants or replications. Detailed originals/registration remain externally unread; confirmed unique-trial, participant and independent-replication totals are unrecorded.

Public availability, access and reading status by material
Material	Public availability	Access status	Actually read	Notes
Stored existing review summary	Preserved copy of the complete parent-verdict stored summary	Stored summary	Summary read	The original ISRCTN31571714 URL is preserved. It registers the same Puhan 2006, 25-person four-month trial, not separate participants or an effect report. Original post-recruitment registration wording is distinguished from currently unread exact dates/plans.
External registration material	Original bibliographic link or needed material; external public availability/access status unverified	Unread; access not attempted	Not read	The original ISRCTN31571714 URL is preserved. It registers the same Puhan 2006, 25-person four-month trial, not separate participants or an effect report. Original post-recruitment registration wording is distinguished from currently unread exact dates/plans.
Registration amendment history	Original bibliographic link or needed material; external public availability/access status unverified	Unread; access not attempted	Not read	The original ISRCTN31571714 URL is preserved. It registers the same Puhan 2006, 25-person four-month trial, not separate participants or an effect report. Original post-recruitment registration wording is distinguished from currently unread exact dates/plans.
Protocol	Original bibliographic link or needed material; external public availability/access status unverified	Unread; access not attempted	Not read	The original ISRCTN31571714 URL is preserved. It registers the same Puhan 2006, 25-person four-month trial, not separate participants or an effect report. Original post-recruitment registration wording is distinguished from currently unread exact dates/plans.
Statistical analysis plan	Original bibliographic link or needed material; external public availability/access status unverified	Unread; access not attempted	Not read	The original ISRCTN31571714 URL is preserved. It registers the same Puhan 2006, 25-person four-month trial, not separate participants or an effect report. Original post-recruitment registration wording is distinguished from currently unread exact dates/plans.
Funding, product-support and COI material	Original bibliographic link or needed material; external public availability/access status unverified	Unread; access not attempted	Not read	The original ISRCTN31571714 URL is preserved. It registers the same Puhan 2006, 25-person four-month trial, not separate participants or an effect report. Original post-recruitment registration wording is distinguished from currently unread exact dates/plans.

Report counts versus independent study counts

The S01 Puhan 2006 paper and S02 ISRCTN31571714 registration are preserved links to the same 25-person four-month didgeridoo lesson/home-practice versus wait-list trial. ESS, AHI, PSQI, bed-partner endpoints, two subclaim sheets and registration are not added as new independent trials, participants or replications. Detailed originals/registration remain externally unread; confirmed unique-trial, participant and independent-replication totals are unrecorded.

Review criteria

Version 1.0 · Criteria record date 2026-10-06. These are Chamgap's own application conditions, informed by the referenced methods. They do not constitute official assessment-tool certification or a new efficacy score.

N01 · Which daytime-sleepiness claim is examined?

Required materials and conditions: Selected sleepiness claim, note/grade and parent verdict
Conditions for verification: Material for Selected sleepiness claim, note/grade and parent verdict must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.
Requirement and applicability: Required
Application exceptions: Preserve original numbers, CIs, P values and study exposure only. Distinguish ESS points from AHI/h, PSQI and subjective bed-partner assessment; waiting from standard care; mean exposure from individual adherence; 25 completers from endpoint denominators; and the same paper/registration. Retrospective registration/historical checks do not become prerecruitment plans or current clinical review. No new arithmetic, effects, CIs, hypothetical numbers, grades, independence certification, playing/breathing methods, training, treatment-replacement or procedure instructions are created.
Why this condition is needed: This condition connects Selected sleepiness claim, note/grade and parent verdict with selected daytime sleepiness in moderate OSA, the structured program/wait list, the same paper/registration, respondents, ESS versus other endpoints, times, denominators and harms.
Referenced methods: Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.

N02 · Which adults with moderate OSA were studied?

Required materials and conditions: Eligibility, baseline characteristics, diagnosis and arm denominators
Conditions for verification: Material for Eligibility, baseline characteristics, diagnosis and arm denominators must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.
Requirement and applicability: Required
Application exceptions: Preserve original numbers, CIs, P values and study exposure only. Distinguish ESS points from AHI/h, PSQI and subjective bed-partner assessment; waiting from standard care; mean exposure from individual adherence; 25 completers from endpoint denominators; and the same paper/registration. Retrospective registration/historical checks do not become prerecruitment plans or current clinical review. No new arithmetic, effects, CIs, hypothetical numbers, grades, independence certification, playing/breathing methods, training, treatment-replacement or procedure instructions are created.
Why this condition is needed: This condition connects Eligibility, baseline characteristics, diagnosis and arm denominators with selected daytime sleepiness in moderate OSA, the structured program/wait list, the same paper/registration, respondents, ESS versus other endpoints, times, denominators and harms.
Referenced methods: Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.

N03 · Which program was studied?

Required materials and conditions: Lessons, home practice, developer and intervention specification
Conditions for verification: Material for Lessons, home practice, developer and intervention specification must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.
Requirement and applicability: Required
Application exceptions: Preserve original numbers, CIs, P values and study exposure only. Distinguish ESS points from AHI/h, PSQI and subjective bed-partner assessment; waiting from standard care; mean exposure from individual adherence; 25 completers from endpoint denominators; and the same paper/registration. Retrospective registration/historical checks do not become prerecruitment plans or current clinical review. No new arithmetic, effects, CIs, hypothetical numbers, grades, independence certification, playing/breathing methods, training, treatment-replacement or procedure instructions are created.
Why this condition is needed: This condition connects Lessons, home practice, developer and intervention specification with selected daytime sleepiness in moderate OSA, the structured program/wait list, the same paper/registration, respondents, ESS versus other endpoints, times, denominators and harms.
Referenced methods: Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.

N04 · Does average practice describe an individual procedure?

Required materials and conditions: Planned exposure, mean actual exposure, distribution and adherence
Conditions for verification: Material for Planned exposure, mean actual exposure, distribution and adherence must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.
Requirement and applicability: Required
Application exceptions: Preserve original numbers, CIs, P values and study exposure only. Distinguish ESS points from AHI/h, PSQI and subjective bed-partner assessment; waiting from standard care; mean exposure from individual adherence; 25 completers from endpoint denominators; and the same paper/registration. Retrospective registration/historical checks do not become prerecruitment plans or current clinical review. No new arithmetic, effects, CIs, hypothetical numbers, grades, independence certification, playing/breathing methods, training, treatment-replacement or procedure instructions are created.
Why this condition is needed: This condition connects Planned exposure, mean actual exposure, distribution and adherence with selected daytime sleepiness in moderate OSA, the structured program/wait list, the same paper/registration, respondents, ESS versus other endpoints, times, denominators and harms.
Referenced methods: Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.

N05 · What does the wait-list comparison establish?

Required materials and conditions: Control care, contact, expectations and concurrent treatment
Conditions for verification: Material for Control care, contact, expectations and concurrent treatment must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.
Requirement and applicability: Required
Application exceptions: Preserve original numbers, CIs, P values and study exposure only. Distinguish ESS points from AHI/h, PSQI and subjective bed-partner assessment; waiting from standard care; mean exposure from individual adherence; 25 completers from endpoint denominators; and the same paper/registration. Retrospective registration/historical checks do not become prerecruitment plans or current clinical review. No new arithmetic, effects, CIs, hypothetical numbers, grades, independence certification, playing/breathing methods, training, treatment-replacement or procedure instructions are created.
Why this condition is needed: This condition connects Control care, contact, expectations and concurrent treatment with selected daytime sleepiness in moderate OSA, the structured program/wait list, the same paper/registration, respondents, ESS versus other endpoints, times, denominators and harms.
Referenced methods: Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.

N06 · Are randomization and concealment detailed?

Required materials and conditions: Allocation sequence, concealment and recruitment processes
Conditions for verification: Material for Allocation sequence, concealment and recruitment processes must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.
Requirement and applicability: Required
Application exceptions: Preserve original numbers, CIs, P values and study exposure only. Distinguish ESS points from AHI/h, PSQI and subjective bed-partner assessment; waiting from standard care; mean exposure from individual adherence; 25 completers from endpoint denominators; and the same paper/registration. Retrospective registration/historical checks do not become prerecruitment plans or current clinical review. No new arithmetic, effects, CIs, hypothetical numbers, grades, independence certification, playing/breathing methods, training, treatment-replacement or procedure instructions are created.
Why this condition is needed: This condition connects Allocation sequence, concealment and recruitment processes with selected daytime sleepiness in moderate OSA, the structured program/wait list, the same paper/registration, respondents, ESS versus other endpoints, times, denominators and harms.
Referenced methods: Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.

N07 · Is unblinded symptom assessment distinguished?

Required materials and conditions: Participant, assessor/analyst masking and expectation differences
Conditions for verification: Material for Participant, assessor/analyst masking and expectation differences must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.
Requirement and applicability: Required
Application exceptions: Preserve original numbers, CIs, P values and study exposure only. Distinguish ESS points from AHI/h, PSQI and subjective bed-partner assessment; waiting from standard care; mean exposure from individual adherence; 25 completers from endpoint denominators; and the same paper/registration. Retrospective registration/historical checks do not become prerecruitment plans or current clinical review. No new arithmetic, effects, CIs, hypothetical numbers, grades, independence certification, playing/breathing methods, training, treatment-replacement or procedure instructions are created.
Why this condition is needed: This condition connects Participant, assessor/analyst masking and expectation differences with selected daytime sleepiness in moderate OSA, the structured program/wait list, the same paper/registration, respondents, ESS versus other endpoints, times, denominators and harms.
Referenced methods: Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.

N08 · What did ESS assess and when?

Required materials and conditions: Scale, assessment window, method and units
Conditions for verification: Material for Scale, assessment window, method and units must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.
Requirement and applicability: Required
Application exceptions: Preserve original numbers, CIs, P values and study exposure only. Distinguish ESS points from AHI/h, PSQI and subjective bed-partner assessment; waiting from standard care; mean exposure from individual adherence; 25 completers from endpoint denominators; and the same paper/registration. Retrospective registration/historical checks do not become prerecruitment plans or current clinical review. No new arithmetic, effects, CIs, hypothetical numbers, grades, independence certification, playing/breathing methods, training, treatment-replacement or procedure instructions are created.
Why this condition is needed: This condition connects Scale, assessment window, method and units with selected daytime sleepiness in moderate OSA, the structured program/wait list, the same paper/registration, respondents, ESS versus other endpoints, times, denominators and harms.
Referenced methods: Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.

N09 · What is the original ESS difference, CI and P value?

Required materials and conditions: Comparative estimate, units, denominators and model
Conditions for verification: Material for Comparative estimate, units, denominators and model must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.
Requirement and applicability: Required
Application exceptions: Preserve original numbers, CIs, P values and study exposure only. Distinguish ESS points from AHI/h, PSQI and subjective bed-partner assessment; waiting from standard care; mean exposure from individual adherence; 25 completers from endpoint denominators; and the same paper/registration. Retrospective registration/historical checks do not become prerecruitment plans or current clinical review. No new arithmetic, effects, CIs, hypothetical numbers, grades, independence certification, playing/breathing methods, training, treatment-replacement or procedure instructions are created.
Why this condition is needed: This condition connects Comparative estimate, units, denominators and model with selected daytime sleepiness in moderate OSA, the structured program/wait list, the same paper/registration, respondents, ESS versus other endpoints, times, denominators and harms.
Referenced methods: Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.

N10 · Are ESS importance and individual distributions verified?

Required materials and conditions: Relevance thresholds, individual changes and uncertainty
Conditions for verification: Material for Relevance thresholds, individual changes and uncertainty must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.
Requirement and applicability: Required
Application exceptions: Preserve original numbers, CIs, P values and study exposure only. Distinguish ESS points from AHI/h, PSQI and subjective bed-partner assessment; waiting from standard care; mean exposure from individual adherence; 25 completers from endpoint denominators; and the same paper/registration. Retrospective registration/historical checks do not become prerecruitment plans or current clinical review. No new arithmetic, effects, CIs, hypothetical numbers, grades, independence certification, playing/breathing methods, training, treatment-replacement or procedure instructions are created.
Why this condition is needed: This condition connects Relevance thresholds, individual changes and uncertainty with selected daytime sleepiness in moderate OSA, the structured program/wait list, the same paper/registration, respondents, ESS versus other endpoints, times, denominators and harms.
Referenced methods: Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.

N11 · Did effects persist after four months?

Required materials and conditions: Assessment duration, intervention cessation and long-term follow-up
Conditions for verification: Material for Assessment duration, intervention cessation and long-term follow-up must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.
Requirement and applicability: Required
Application exceptions: Preserve original numbers, CIs, P values and study exposure only. Distinguish ESS points from AHI/h, PSQI and subjective bed-partner assessment; waiting from standard care; mean exposure from individual adherence; 25 completers from endpoint denominators; and the same paper/registration. Retrospective registration/historical checks do not become prerecruitment plans or current clinical review. No new arithmetic, effects, CIs, hypothetical numbers, grades, independence certification, playing/breathing methods, training, treatment-replacement or procedure instructions are created.
Why this condition is needed: This condition connects Assessment duration, intervention cessation and long-term follow-up with selected daytime sleepiness in moderate OSA, the structured program/wait list, the same paper/registration, respondents, ESS versus other endpoints, times, denominators and harms.
Referenced methods: Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.

N12 · Is AHI a separate result from ESS?

Required materials and conditions: Distinguishing ESS/AHI definitions, results and units
Conditions for verification: Material for Distinguishing ESS/AHI definitions, results and units must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.
Requirement and applicability: Required
Application exceptions: Preserve original numbers, CIs, P values and study exposure only. Distinguish ESS points from AHI/h, PSQI and subjective bed-partner assessment; waiting from standard care; mean exposure from individual adherence; 25 completers from endpoint denominators; and the same paper/registration. Retrospective registration/historical checks do not become prerecruitment plans or current clinical review. No new arithmetic, effects, CIs, hypothetical numbers, grades, independence certification, playing/breathing methods, training, treatment-replacement or procedure instructions are created.
Why this condition is needed: This condition connects Distinguishing ESS/AHI definitions, results and units with selected daytime sleepiness in moderate OSA, the structured program/wait list, the same paper/registration, respondents, ESS versus other endpoints, times, denominators and harms.
Referenced methods: Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.

N13 · Is the null PSQI result also retained?

Required materials and conditions: Endpoint-specific effects, units and uncertainty
Conditions for verification: Material for Endpoint-specific effects, units and uncertainty must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.
Requirement and applicability: Required
Application exceptions: Preserve original numbers, CIs, P values and study exposure only. Distinguish ESS points from AHI/h, PSQI and subjective bed-partner assessment; waiting from standard care; mean exposure from individual adherence; 25 completers from endpoint denominators; and the same paper/registration. Retrospective registration/historical checks do not become prerecruitment plans or current clinical review. No new arithmetic, effects, CIs, hypothetical numbers, grades, independence certification, playing/breathing methods, training, treatment-replacement or procedure instructions are created.
Why this condition is needed: This condition connects Endpoint-specific effects, units and uncertainty with selected daytime sleepiness in moderate OSA, the structured program/wait list, the same paper/registration, respondents, ESS versus other endpoints, times, denominators and harms.
Referenced methods: Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.

N14 · Are the bed-partner respondent and endpoint distinguished?

Required materials and conditions: Respondent, scale, endpoint and denominators
Conditions for verification: Material for Respondent, scale, endpoint and denominators must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.
Requirement and applicability: Required
Application exceptions: Preserve original numbers, CIs, P values and study exposure only. Distinguish ESS points from AHI/h, PSQI and subjective bed-partner assessment; waiting from standard care; mean exposure from individual adherence; 25 completers from endpoint denominators; and the same paper/registration. Retrospective registration/historical checks do not become prerecruitment plans or current clinical review. No new arithmetic, effects, CIs, hypothetical numbers, grades, independence certification, playing/breathing methods, training, treatment-replacement or procedure instructions are created.
Why this condition is needed: This condition connects Respondent, scale, endpoint and denominators with selected daytime sleepiness in moderate OSA, the structured program/wait list, the same paper/registration, respondents, ESS versus other endpoints, times, denominators and harms.
Referenced methods: Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.

N15 · Does completion by everyone establish every analysis denominator?

Required materials and conditions: Allocation, completion, endpoint analyses and missingness
Conditions for verification: Material for Allocation, completion, endpoint analyses and missingness must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.
Requirement and applicability: Required
Application exceptions: Preserve original numbers, CIs, P values and study exposure only. Distinguish ESS points from AHI/h, PSQI and subjective bed-partner assessment; waiting from standard care; mean exposure from individual adherence; 25 completers from endpoint denominators; and the same paper/registration. Retrospective registration/historical checks do not become prerecruitment plans or current clinical review. No new arithmetic, effects, CIs, hypothetical numbers, grades, independence certification, playing/breathing methods, training, treatment-replacement or procedure instructions are created.
Why this condition is needed: This condition connects Allocation, completion, endpoint analyses and missingness with selected daytime sleepiness in moderate OSA, the structured program/wait list, the same paper/registration, respondents, ESS versus other endpoints, times, denominators and harms.
Referenced methods: Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.

N16 · Are concurrent treatment, weight and lifestyle changes verified?

Required materials and conditions: Arm-specific concurrent care, exposure and adjustment
Conditions for verification: Material for Arm-specific concurrent care, exposure and adjustment must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.
Requirement and applicability: Required
Application exceptions: Preserve original numbers, CIs, P values and study exposure only. Distinguish ESS points from AHI/h, PSQI and subjective bed-partner assessment; waiting from standard care; mean exposure from individual adherence; 25 completers from endpoint denominators; and the same paper/registration. Retrospective registration/historical checks do not become prerecruitment plans or current clinical review. No new arithmetic, effects, CIs, hypothetical numbers, grades, independence certification, playing/breathing methods, training, treatment-replacement or procedure instructions are created.
Why this condition is needed: This condition connects Arm-specific concurrent care, exposure and adjustment with selected daytime sleepiness in moderate OSA, the structured program/wait list, the same paper/registration, respondents, ESS versus other endpoints, times, denominators and harms.
Referenced methods: Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.

N17 · When was ISRCTN registration made?

Required materials and conditions: Registration identity, recruitment/registration timing and original records
Conditions for verification: Material for Registration identity, recruitment/registration timing and original records must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.
Requirement and applicability: Required
Application exceptions: Preserve original numbers, CIs, P values and study exposure only. Distinguish ESS points from AHI/h, PSQI and subjective bed-partner assessment; waiting from standard care; mean exposure from individual adherence; 25 completers from endpoint denominators; and the same paper/registration. Retrospective registration/historical checks do not become prerecruitment plans or current clinical review. No new arithmetic, effects, CIs, hypothetical numbers, grades, independence certification, playing/breathing methods, training, treatment-replacement or procedure instructions are created.
Why this condition is needed: This condition connects Registration identity, recruitment/registration timing and original records with selected daytime sleepiness in moderate OSA, the structured program/wait list, the same paper/registration, respondents, ESS versus other endpoints, times, denominators and harms.
Referenced methods: Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.

N18 · Does an ESS main endpoint establish the complete prior plan?

Required materials and conditions: Separating main-endpoint wording, registration, protocol and SAP
Conditions for verification: Material for Separating main-endpoint wording, registration, protocol and SAP must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.
Requirement and applicability: Required
Application exceptions: Preserve original numbers, CIs, P values and study exposure only. Distinguish ESS points from AHI/h, PSQI and subjective bed-partner assessment; waiting from standard care; mean exposure from individual adherence; 25 completers from endpoint denominators; and the same paper/registration. Retrospective registration/historical checks do not become prerecruitment plans or current clinical review. No new arithmetic, effects, CIs, hypothetical numbers, grades, independence certification, playing/breathing methods, training, treatment-replacement or procedure instructions are created.
Why this condition is needed: This condition connects Separating main-endpoint wording, registration, protocol and SAP with selected daytime sleepiness in moderate OSA, the structured program/wait list, the same paper/registration, respondents, ESS versus other endpoints, times, denominators and harms.
Referenced methods: Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.

N19 · Are multiple endpoints and test models distinguished?

Required materials and conditions: All endpoints, tests, adjustment and multiplicity
Conditions for verification: Material for All endpoints, tests, adjustment and multiplicity must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.
Requirement and applicability: Required
Application exceptions: Preserve original numbers, CIs, P values and study exposure only. Distinguish ESS points from AHI/h, PSQI and subjective bed-partner assessment; waiting from standard care; mean exposure from individual adherence; 25 completers from endpoint denominators; and the same paper/registration. Retrospective registration/historical checks do not become prerecruitment plans or current clinical review. No new arithmetic, effects, CIs, hypothetical numbers, grades, independence certification, playing/breathing methods, training, treatment-replacement or procedure instructions are created.
Why this condition is needed: This condition connects All endpoints, tests, adjustment and multiplicity with selected daytime sleepiness in moderate OSA, the structured program/wait list, the same paper/registration, respondents, ESS versus other endpoints, times, denominators and harms.
Referenced methods: Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.

N20 · Are the paper and registration separate trials?

Required materials and conditions: Reports, registration, trial family and population links
Conditions for verification: Material for Reports, registration, trial family and population links must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.
Requirement and applicability: Required
Application exceptions: Preserve original numbers, CIs, P values and study exposure only. Distinguish ESS points from AHI/h, PSQI and subjective bed-partner assessment; waiting from standard care; mean exposure from individual adherence; 25 completers from endpoint denominators; and the same paper/registration. Retrospective registration/historical checks do not become prerecruitment plans or current clinical review. No new arithmetic, effects, CIs, hypothetical numbers, grades, independence certification, playing/breathing methods, training, treatment-replacement or procedure instructions are created.
Why this condition is needed: This condition connects Reports, registration, trial family and population links with selected daytime sleepiness in moderate OSA, the structured program/wait list, the same paper/registration, respondents, ESS versus other endpoints, times, denominators and harms.
Referenced methods: Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.

N21 · Was the sleepiness effect independently replicated?

Required materials and conditions: Separate trials with the same population/intervention/comparator
Conditions for verification: Material for Separate trials with the same population/intervention/comparator must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.
Requirement and applicability: Required
Application exceptions: Preserve original numbers, CIs, P values and study exposure only. Distinguish ESS points from AHI/h, PSQI and subjective bed-partner assessment; waiting from standard care; mean exposure from individual adherence; 25 completers from endpoint denominators; and the same paper/registration. Retrospective registration/historical checks do not become prerecruitment plans or current clinical review. No new arithmetic, effects, CIs, hypothetical numbers, grades, independence certification, playing/breathing methods, training, treatment-replacement or procedure instructions are created.
Why this condition is needed: This condition connects Separate trials with the same population/intervention/comparator with selected daytime sleepiness in moderate OSA, the structured program/wait list, the same paper/registration, respondents, ESS versus other endpoints, times, denominators and harms.
Referenced methods: Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.

N22 · Does this apply to other BMIs, severities or ages?

Required materials and conditions: Direct population-specific material and subgroup plans
Conditions for verification: Material for Direct population-specific material and subgroup plans must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.
Requirement and applicability: Required
Application exceptions: Preserve original numbers, CIs, P values and study exposure only. Distinguish ESS points from AHI/h, PSQI and subjective bed-partner assessment; waiting from standard care; mean exposure from individual adherence; 25 completers from endpoint denominators; and the same paper/registration. Retrospective registration/historical checks do not become prerecruitment plans or current clinical review. No new arithmetic, effects, CIs, hypothetical numbers, grades, independence certification, playing/breathing methods, training, treatment-replacement or procedure instructions are created.
Why this condition is needed: This condition connects Direct population-specific material and subgroup plans with selected daytime sleepiness in moderate OSA, the structured program/wait list, the same paper/registration, respondents, ESS versus other endpoints, times, denominators and harms.
Referenced methods: Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.

N23 · Do sleepiness/AHI signals establish replacement of standard therapy?

Required materials and conditions: Direct standard-treatment comparisons and clinical outcomes
Conditions for verification: Material for Direct standard-treatment comparisons and clinical outcomes must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.
Requirement and applicability: Required
Application exceptions: Preserve original numbers, CIs, P values and study exposure only. Distinguish ESS points from AHI/h, PSQI and subjective bed-partner assessment; waiting from standard care; mean exposure from individual adherence; 25 completers from endpoint denominators; and the same paper/registration. Retrospective registration/historical checks do not become prerecruitment plans or current clinical review. No new arithmetic, effects, CIs, hypothetical numbers, grades, independence certification, playing/breathing methods, training, treatment-replacement or procedure instructions are created.
Why this condition is needed: This condition connects Direct standard-treatment comparisons and clinical outcomes with selected daytime sleepiness in moderate OSA, the structured program/wait list, the same paper/registration, respondents, ESS versus other endpoints, times, denominators and harms.
Referenced methods: Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.

N24 · Are funding, the developer-instructor and conflicts distinguished?

Required materials and conditions: Original support, product, employee/developer and COI records
Conditions for verification: Material for Original support, product, employee/developer and COI records must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.
Requirement and applicability: Required
Application exceptions: Preserve original numbers, CIs, P values and study exposure only. Distinguish ESS points from AHI/h, PSQI and subjective bed-partner assessment; waiting from standard care; mean exposure from individual adherence; 25 completers from endpoint denominators; and the same paper/registration. Retrospective registration/historical checks do not become prerecruitment plans or current clinical review. No new arithmetic, effects, CIs, hypothetical numbers, grades, independence certification, playing/breathing methods, training, treatment-replacement or procedure instructions are created.
Why this condition is needed: This condition connects Original support, product, employee/developer and COI records with selected daytime sleepiness in moderate OSA, the structured program/wait list, the same paper/registration, respondents, ESS versus other endpoints, times, denominators and harms.
Referenced methods: Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.

N25 · What was reported about safety and sample-size limits?

Required materials and conditions: Harm collection, exposure, arm denominators and follow-up
Conditions for verification: Material for Harm collection, exposure, arm denominators and follow-up must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.
Requirement and applicability: Supplementary
Application exceptions: Preserve original numbers, CIs, P values and study exposure only. Distinguish ESS points from AHI/h, PSQI and subjective bed-partner assessment; waiting from standard care; mean exposure from individual adherence; 25 completers from endpoint denominators; and the same paper/registration. Retrospective registration/historical checks do not become prerecruitment plans or current clinical review. No new arithmetic, effects, CIs, hypothetical numbers, grades, independence certification, playing/breathing methods, training, treatment-replacement or procedure instructions are created.
Why this condition is needed: This condition connects Harm collection, exposure, arm denominators and follow-up with selected daytime sleepiness in moderate OSA, the structured program/wait list, the same paper/registration, respondents, ESS versus other endpoints, times, denominators and harms.
Referenced methods: Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.

N26 · Are parent values, subclaim grade and the evidence date separated?

Required materials and conditions: Parent/subclaim original values and historical dates
Conditions for verification: Material for Parent/subclaim original values and historical dates must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.
Requirement and applicability: Required
Application exceptions: Preserve original numbers, CIs, P values and study exposure only. Distinguish ESS points from AHI/h, PSQI and subjective bed-partner assessment; waiting from standard care; mean exposure from individual adherence; 25 completers from endpoint denominators; and the same paper/registration. Retrospective registration/historical checks do not become prerecruitment plans or current clinical review. No new arithmetic, effects, CIs, hypothetical numbers, grades, independence certification, playing/breathing methods, training, treatment-replacement or procedure instructions are created.
Why this condition is needed: This condition connects Parent/subclaim original values and historical dates with selected daytime sleepiness in moderate OSA, the structured program/wait list, the same paper/registration, respondents, ESS versus other endpoints, times, denominators and harms.
Referenced methods: Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.

N27 · Are historical checks the current reading?

Required materials and conditions: Historical review statements, summary use and external access
Conditions for verification: Material for Historical review statements, summary use and external access must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.
Requirement and applicability: Required
Application exceptions: Preserve original numbers, CIs, P values and study exposure only. Distinguish ESS points from AHI/h, PSQI and subjective bed-partner assessment; waiting from standard care; mean exposure from individual adherence; 25 completers from endpoint denominators; and the same paper/registration. Retrospective registration/historical checks do not become prerecruitment plans or current clinical review. No new arithmetic, effects, CIs, hypothetical numbers, grades, independence certification, playing/breathing methods, training, treatment-replacement or procedure instructions are created.
Why this condition is needed: This condition connects Historical review statements, summary use and external access with selected daytime sleepiness in moderate OSA, the structured program/wait list, the same paper/registration, respondents, ESS versus other endpoints, times, denominators and harms.
Referenced methods: Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.

N28 · Which materials would trigger an update?

Required materials and conditions: Linking summary reading, unread originals and needed material
Conditions for verification: Material for Linking summary reading, unread originals and needed material must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.
Requirement and applicability: Required
Application exceptions: Preserve original numbers, CIs, P values and study exposure only. Distinguish ESS points from AHI/h, PSQI and subjective bed-partner assessment; waiting from standard care; mean exposure from individual adherence; 25 completers from endpoint denominators; and the same paper/registration. Retrospective registration/historical checks do not become prerecruitment plans or current clinical review. No new arithmetic, effects, CIs, hypothetical numbers, grades, independence certification, playing/breathing methods, training, treatment-replacement or procedure instructions are created.
Why this condition is needed: This condition connects Linking summary reading, unread originals and needed material with selected daytime sleepiness in moderate OSA, the structured program/wait list, the same paper/registration, respondents, ESS versus other endpoints, times, denominators and harms.
Referenced methods: Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.

Referenced methods and the sections actually reviewed

M03 · Cochrane Handbook 6.5 (2024), chapter updated 2023-08

Official methodology · §3.1, §3.2.1–3.2.3, MECIR C5/C7/C13

Referenced principle: Clearly record the question, eligibility conditions and reasons for changes, and distinguish variations in interventions.
Extent of review: Preserved method HTML copies; no current method-content re-review or official tool execution

M04 · Cochrane Handbook 6.5.1 (2025), chapter updated 2025-03

Official methodology · §4.5, §4.6.1–4.6.3, MECIR C42

Referenced principle: Distinguish studies from reports and link them; do not omit a study solely because results are unreported.
Extent of review: Preserved method HTML copies; no current method-content re-review or official tool execution

M08 · Cochrane Handbook 6.5 (2024), chapter updated 2019-10

Official methodology · §8.1–8.2.3, Table 8.2.a

Referenced principle: Define the outcome and effect of interest, then examine randomization, deviations, missing data, measurement and selective reporting.
Extent of review: Preserved method HTML copies; no current method-content re-review or official tool execution

M15 · Cochrane Handbook 6.5 (2024), chapter updated 2023-08

Official methodology · §15.2.4, §15.3.1–15.3.3

Referenced principle: Distinguish effect estimates, intervals, importance and applicability. Sample size alone does not determine precision.
Extent of review: Preserved method HTML copies; no current method-content re-review or official tool execution

M19 · Cochrane Handbook 6.5 (2024), chapter updated 2019-10

Official methodology · §19.1.2, §19.2.1–19.2.4

Referenced principle: Harm questions may require different designs, populations and follow-up from efficacy questions. Case reports do not establish incidence rates.
Extent of review: Preserved method HTML copies; no current method-content re-review or official tool execution

What the statuses mean

Met: A state used when required evidence is confirmed after user review. This production does not declare that review complete.
Partly verified: Some information in the stored summary is linked into the table. External comparison/content review is not complete.
Unverified: The article leaves this unverified, or required material is absent from the current stored summary. This is distinct from zero, absence or safety.
Review incomplete: User review pending.
Not reported: Not reported within the stored material actually read; not extended to the entire primary paper.
Inaccessible: Means an actual access failure. Access not attempted here is not assigned this state.
Not applicable: Not used as a substitute for an evidence gap.
Conflicting data: Requires an observed disagreement under the same comparison criteria; not automatically judged in this production.
Insufficient evidence for the conditions: Marks a gap in additional material required by the selected conditions; not a new efficacy grade.

Change history

2026-10-16 · Public page/material version 1.0

Public reader pages and material were prepared from the existing 28 items. No new clinical searches, verification-state changes or scoring were performed.

The stored-material review date (Not recorded) and original evidence cut-off (2026-09-07) were retained unchanged.

Researcher downloads

These materials provide the same evidence, scope and verification status as this page.

View all item details

N01 · Which daytime-sleepiness claim is examined?

Current findings: The selected claim is reduced daytime sleepiness in moderate OSA. Original grade C and the ESS between-group difference of −3.0 points in its note are retained. Subclaim score, status and axes are absent; parent C50 does not fill a subclaim score.
Verification status: Partly verified
Materials actually read: Stored summary read; external abstracts, full texts, registration, protocols, SAPs and support disclosures unread
Why unverified: The selected claim, parent material and reports are distinguished and transferred from the stored summary. Detailed original material is unverified and review of existing content remains incomplete. This does not establish completed clinical review or certification.
Reason for missing information: Separate subclaim score, status and axes are absent from the original. The selected claim and parent verdict must be distinguished.
Required materials and conditions: Selected sleepiness claim, note/grade and parent verdict
Materials to obtain first: Separate subclaim score, status and axes are absent from the original. The selected claim and parent verdict must be distinguished.
Further research: Material needed: Separate subclaim score, status and axes are absent from the original. The selected claim and parent verdict must be distinguished. This records needed materials; no new research was executed.
Remaining uncertainty: External original material is unread and review of existing content remains incomplete. Original grades, scores, axes, historical verification and independence statements are not treated as new verdicts or certification.
Conditions for verification: Material for Selected sleepiness claim, note/grade and parent verdict must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.
Why this condition is needed: This condition connects Selected sleepiness claim, note/grade and parent verdict with selected daytime sleepiness in moderate OSA, the structured program/wait list, the same paper/registration, respondents, ESS versus other endpoints, times, denominators and harms.
Application exceptions: Preserve original numbers, CIs, P values and study exposure only. Distinguish ESS points from AHI/h, PSQI and subjective bed-partner assessment; waiting from standard care; mean exposure from individual adherence; 25 completers from endpoint denominators; and the same paper/registration. Retrospective registration/historical checks do not become prerecruitment plans or current clinical review. No new arithmetic, effects, CIs, hypothetical numbers, grades, independence certification, playing/breathing methods, training, treatment-replacement or procedure instructions are created.
Referenced methods: Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.

Related sources S01 S02

N02 · Which adults with moderate OSA were studied?

Current findings: The original population is 25 adults with moderate OSA, BMI below 30 and AHI 15–30/h. This is not extended to every BMI, severity, age or sleep-disorder population.
Verification status: Partly verified
Materials actually read: Stored summary read; external abstracts, full texts, registration, protocols, SAPs and support disclosures unread
Why unverified: The selected claim, parent material and reports are distinguished and transferred from the stored summary. Detailed original material is unverified and review of existing content remains incomplete. This does not establish completed clinical review or certification.
Reason for missing information: Exact age, sex, baseline ESS, diagnostic procedures and arm allocation denominators are unverified.
Required materials and conditions: Eligibility, baseline characteristics, diagnosis and arm denominators
Materials to obtain first: Exact age, sex, baseline ESS, diagnostic procedures and arm allocation denominators are unverified.
Further research: Material needed: Exact age, sex, baseline ESS, diagnostic procedures and arm allocation denominators are unverified. This records needed materials; no new research was executed.
Remaining uncertainty: External original material is unread and review of existing content remains incomplete. Original grades, scores, axes, historical verification and independence statements are not treated as new verdicts or certification.
Conditions for verification: Material for Eligibility, baseline characteristics, diagnosis and arm denominators must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.
Why this condition is needed: This condition connects Eligibility, baseline characteristics, diagnosis and arm denominators with selected daytime sleepiness in moderate OSA, the structured program/wait list, the same paper/registration, respondents, ESS versus other endpoints, times, denominators and harms.
Application exceptions: Preserve original numbers, CIs, P values and study exposure only. Distinguish ESS points from AHI/h, PSQI and subjective bed-partner assessment; waiting from standard care; mean exposure from individual adherence; 25 completers from endpoint denominators; and the same paper/registration. Retrospective registration/historical checks do not become prerecruitment plans or current clinical review. No new arithmetic, effects, CIs, hypothetical numbers, grades, independence certification, playing/breathing methods, training, treatment-replacement or procedure instructions are created.
Referenced methods: Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.

Related sources S01

N03 · Which program was studied?

Current findings: The original records a structured didgeridoo lesson/home-practice program. This is not changed into a particular instrument-brand effect or an equivalent effect from all playing/breathing training.
Verification status: Partly verified
Materials actually read: Stored summary read; external abstracts, full texts, registration, protocols, SAPs and support disclosures unread
Why unverified: The selected claim, parent material and reports are distinguished and transferred from the stored summary. Detailed original material is unverified and review of existing content remains incomplete. This does not establish completed clinical review or certification.
Reason for missing information: Lesson components, contact, individual actual practice and generalizable components are unverified.
Required materials and conditions: Lessons, home practice, developer and intervention specification
Materials to obtain first: Lesson components, contact, individual actual practice and generalizable components are unverified.
Further research: Material needed: Lesson components, contact, individual actual practice and generalizable components are unverified. This records needed materials; no new research was executed.
Remaining uncertainty: External original material is unread and review of existing content remains incomplete. Original grades, scores, axes, historical verification and independence statements are not treated as new verdicts or certification.
Conditions for verification: Material for Lessons, home practice, developer and intervention specification must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.
Why this condition is needed: This condition connects Lessons, home practice, developer and intervention specification with selected daytime sleepiness in moderate OSA, the structured program/wait list, the same paper/registration, respondents, ESS versus other endpoints, times, denominators and harms.
Application exceptions: Preserve original numbers, CIs, P values and study exposure only. Distinguish ESS points from AHI/h, PSQI and subjective bed-partner assessment; waiting from standard care; mean exposure from individual adherence; 25 completers from endpoint denominators; and the same paper/registration. Retrospective registration/historical checks do not become prerecruitment plans or current clinical review. No new arithmetic, effects, CIs, hypothetical numbers, grades, independence certification, playing/breathing methods, training, treatment-replacement or procedure instructions are created.
Referenced methods: Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.

Related sources S01

N04 · Does average practice describe an individual procedure?

Current findings: Mean 5.9 days weekly, 25.3 minutes per session and approximately 25 minutes in the original intervention name describe study exposure. They are not treated as equal exposure for everyone or recommended procedures, and totals are not newly converted.
Verification status: Partly verified
Materials actually read: Stored summary read; external abstracts, full texts, registration, protocols, SAPs and support disclosures unread
Why unverified: The selected claim, parent material and reports are distinguished and transferred from the stored summary. Detailed original material is unverified and review of existing content remains incomplete. This does not establish completed clinical review or certification.
Reason for missing information: Planned exposure, individual distributions, discontinuation, adherence assessment and ESS by exposure are unverified.
Required materials and conditions: Planned exposure, mean actual exposure, distribution and adherence
Materials to obtain first: Planned exposure, individual distributions, discontinuation, adherence assessment and ESS by exposure are unverified.
Further research: Material needed: Planned exposure, individual distributions, discontinuation, adherence assessment and ESS by exposure are unverified. This records needed materials; no new research was executed.
Remaining uncertainty: External original material is unread and review of existing content remains incomplete. Original grades, scores, axes, historical verification and independence statements are not treated as new verdicts or certification.
Conditions for verification: Material for Planned exposure, mean actual exposure, distribution and adherence must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.
Why this condition is needed: This condition connects Planned exposure, mean actual exposure, distribution and adherence with selected daytime sleepiness in moderate OSA, the structured program/wait list, the same paper/registration, respondents, ESS versus other endpoints, times, denominators and harms.
Application exceptions: Preserve original numbers, CIs, P values and study exposure only. Distinguish ESS points from AHI/h, PSQI and subjective bed-partner assessment; waiting from standard care; mean exposure from individual adherence; 25 completers from endpoint denominators; and the same paper/registration. Retrospective registration/historical checks do not become prerecruitment plans or current clinical review. No new arithmetic, effects, CIs, hypothetical numbers, grades, independence certification, playing/breathing methods, training, treatment-replacement or procedure instructions are created.
Referenced methods: Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.

Related sources S01

N05 · What does the wait-list comparison establish?

Current findings: Paper S01 is a randomized wait-list comparison. It is not a direct comparison with standard OSA therapy, another instrument or equal-contact sham.
Verification status: Partly verified
Materials actually read: Stored summary read; external abstracts, full texts, registration, protocols, SAPs and support disclosures unread
Why unverified: The selected claim, parent material and reports are distinguished and transferred from the stored summary. Detailed original material is unverified and review of existing content remains incomplete. This does not establish completed clinical review or certification.
Reason for missing information: Detailed wait-list care, contact, expectation differences and concurrent treatment are unverified.
Required materials and conditions: Control care, contact, expectations and concurrent treatment
Materials to obtain first: Detailed wait-list care, contact, expectation differences and concurrent treatment are unverified.
Further research: Material needed: Detailed wait-list care, contact, expectation differences and concurrent treatment are unverified. This records needed materials; no new research was executed.
Remaining uncertainty: External original material is unread and review of existing content remains incomplete. Original grades, scores, axes, historical verification and independence statements are not treated as new verdicts or certification.
Conditions for verification: Material for Control care, contact, expectations and concurrent treatment must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.
Why this condition is needed: This condition connects Control care, contact, expectations and concurrent treatment with selected daytime sleepiness in moderate OSA, the structured program/wait list, the same paper/registration, respondents, ESS versus other endpoints, times, denominators and harms.
Application exceptions: Preserve original numbers, CIs, P values and study exposure only. Distinguish ESS points from AHI/h, PSQI and subjective bed-partner assessment; waiting from standard care; mean exposure from individual adherence; 25 completers from endpoint denominators; and the same paper/registration. Retrospective registration/historical checks do not become prerecruitment plans or current clinical review. No new arithmetic, effects, CIs, hypothetical numbers, grades, independence certification, playing/breathing methods, training, treatment-replacement or procedure instructions are created.
Referenced methods: Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.

Related sources S01

N06 · Are randomization and concealment detailed?

Current findings: The S01 design and stored report record random allocation. The summary does not establish sequence generation, allocation concealment or processes before/after recruitment.
Verification status: Partly verified
Materials actually read: Stored summary read; external abstracts, full texts, registration, protocols, SAPs and support disclosures unread
Why unverified: The selected claim, parent material and reports are distinguished and transferred from the stored summary. Detailed original material is unverified and review of existing content remains incomplete. This does not establish completed clinical review or certification.
Reason for missing information: Sequence generation, concealment, responsible staff and recruitment/allocation processes are unverified.
Required materials and conditions: Allocation sequence, concealment and recruitment processes
Materials to obtain first: Sequence generation, concealment, responsible staff and recruitment/allocation processes are unverified.
Further research: Material needed: Sequence generation, concealment, responsible staff and recruitment/allocation processes are unverified. This records needed materials; no new research was executed.
Remaining uncertainty: External original material is unread and review of existing content remains incomplete. Original grades, scores, axes, historical verification and independence statements are not treated as new verdicts or certification.
Conditions for verification: Material for Allocation sequence, concealment and recruitment processes must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.
Why this condition is needed: This condition connects Allocation sequence, concealment and recruitment processes with selected daytime sleepiness in moderate OSA, the structured program/wait list, the same paper/registration, respondents, ESS versus other endpoints, times, denominators and harms.
Application exceptions: Preserve original numbers, CIs, P values and study exposure only. Distinguish ESS points from AHI/h, PSQI and subjective bed-partner assessment; waiting from standard care; mean exposure from individual adherence; 25 completers from endpoint denominators; and the same paper/registration. Retrospective registration/historical checks do not become prerecruitment plans or current clinical review. No new arithmetic, effects, CIs, hypothetical numbers, grades, independence certification, playing/breathing methods, training, treatment-replacement or procedure instructions are created.
Referenced methods: Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.

Related sources S01

N07 · Is unblinded symptom assessment distinguished?

Current findings: The stored report states that participants knew their intervention and identifies unblinded subjective symptom assessment as a limitation. Objective AHI does not substitute for ESS masking or control of expectation effects.
Verification status: Partly verified
Materials actually read: Stored summary read; external abstracts, full texts, registration, protocols, SAPs and support disclosures unread
Why unverified: The selected claim, parent material and reports are distinguished and transferred from the stored summary. Detailed original material is unverified and review of existing content remains incomplete. This does not establish completed clinical review or certification.
Reason for missing information: Assessor/analyst masking, contact/expectation differences and their control are unverified.
Required materials and conditions: Participant, assessor/analyst masking and expectation differences
Materials to obtain first: Assessor/analyst masking, contact/expectation differences and their control are unverified.
Further research: Material needed: Assessor/analyst masking, contact/expectation differences and their control are unverified. This records needed materials; no new research was executed.
Remaining uncertainty: External original material is unread and review of existing content remains incomplete. Original grades, scores, axes, historical verification and independence statements are not treated as new verdicts or certification.
Conditions for verification: Material for Participant, assessor/analyst masking and expectation differences must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.
Why this condition is needed: This condition connects Participant, assessor/analyst masking and expectation differences with selected daytime sleepiness in moderate OSA, the structured program/wait list, the same paper/registration, respondents, ESS versus other endpoints, times, denominators and harms.
Application exceptions: Preserve original numbers, CIs, P values and study exposure only. Distinguish ESS points from AHI/h, PSQI and subjective bed-partner assessment; waiting from standard care; mean exposure from individual adherence; 25 completers from endpoint denominators; and the same paper/registration. Retrospective registration/historical checks do not become prerecruitment plans or current clinical review. No new arithmetic, effects, CIs, hypothetical numbers, grades, independence certification, playing/breathing methods, training, treatment-replacement or procedure instructions are created.
Referenced methods: Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.

Related sources S01

N08 · What did ESS assess and when?

Current findings: The S01 main endpoint is the four-month Epworth Sleepiness Scale (ESS) score. AHI/h, PSQI and bed-partner disturbance are different measures.
Verification status: Partly verified
Materials actually read: Stored summary read; external abstracts, full texts, registration, protocols, SAPs and support disclosures unread
Why unverified: The selected claim, parent material and reports are distinguished and transferred from the stored summary. Detailed original material is unverified and review of existing content remains incomplete. This does not establish completed clinical review or certification.
Reason for missing information: Scale administration, recall period, assessment timing, standardization and baseline distributions are unverified.
Required materials and conditions: Scale, assessment window, method and units
Materials to obtain first: Scale administration, recall period, assessment timing, standardization and baseline distributions are unverified.
Further research: Material needed: Scale administration, recall period, assessment timing, standardization and baseline distributions are unverified. This records needed materials; no new research was executed.
Remaining uncertainty: External original material is unread and review of existing content remains incomplete. Original grades, scores, axes, historical verification and independence statements are not treated as new verdicts or certification.
Conditions for verification: Material for Scale, assessment window, method and units must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.
Why this condition is needed: This condition connects Scale, assessment window, method and units with selected daytime sleepiness in moderate OSA, the structured program/wait list, the same paper/registration, respondents, ESS versus other endpoints, times, denominators and harms.
Application exceptions: Preserve original numbers, CIs, P values and study exposure only. Distinguish ESS points from AHI/h, PSQI and subjective bed-partner assessment; waiting from standard care; mean exposure from individual adherence; 25 completers from endpoint denominators; and the same paper/registration. Retrospective registration/historical checks do not become prerecruitment plans or current clinical review. No new arithmetic, effects, CIs, hypothetical numbers, grades, independence certification, playing/breathing methods, training, treatment-replacement or procedure instructions are created.
Referenced methods: Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.

Related sources S01

N09 · What is the original ESS difference, CI and P value?

Current findings: The ESS between-group difference of −3.0 points (95% CI −5.7 to −0.3, P=.03) is preserved. It is not transferred into within-arm change, treatment-replacement differences or cure rates.
Verification status: Partly verified
Materials actually read: Stored summary read; external abstracts, full texts, registration, protocols, SAPs and support disclosures unread
Why unverified: The selected claim, parent material and reports are distinguished and transferred from the stored summary. Detailed original material is unverified and review of existing content remains incomplete. This does not establish completed clinical review or certification.
Reason for missing information: Original arm values, exact analysis denominators, model, baseline adjustment and outcome-hierarchy details are unverified.
Required materials and conditions: Comparative estimate, units, denominators and model
Materials to obtain first: Original arm values, exact analysis denominators, model, baseline adjustment and outcome-hierarchy details are unverified.
Further research: Material needed: Original arm values, exact analysis denominators, model, baseline adjustment and outcome-hierarchy details are unverified. This records needed materials; no new research was executed.
Remaining uncertainty: External original material is unread and review of existing content remains incomplete. Original grades, scores, axes, historical verification and independence statements are not treated as new verdicts or certification.
Conditions for verification: Material for Comparative estimate, units, denominators and model must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.
Why this condition is needed: This condition connects Comparative estimate, units, denominators and model with selected daytime sleepiness in moderate OSA, the structured program/wait list, the same paper/registration, respondents, ESS versus other endpoints, times, denominators and harms.
Application exceptions: Preserve original numbers, CIs, P values and study exposure only. Distinguish ESS points from AHI/h, PSQI and subjective bed-partner assessment; waiting from standard care; mean exposure from individual adherence; 25 completers from endpoint denominators; and the same paper/registration. Retrospective registration/historical checks do not become prerecruitment plans or current clinical review. No new arithmetic, effects, CIs, hypothetical numbers, grades, independence certification, playing/breathing methods, training, treatment-replacement or procedure instructions are created.
Referenced methods: Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.

Related sources S01

N10 · Are ESS importance and individual distributions verified?

Current findings: The stored report describes a symptom signal from one small trial. −3.0 points and statistical significance alone do not establish perceived or clinically important improvement for every participant.
Verification status: Unverified
Materials actually read: Stored summary read; external abstracts, full texts, registration, protocols, SAPs and support disclosures unread
Why unverified: The selected claim, parent material and reports are distinguished and transferred from the stored summary. Detailed original material is unverified and review of existing content remains incomplete. This does not establish completed clinical review or certification.
Reason for missing information: Prior relevance thresholds, individual distributions, response definitions and persistence are unverified.
Required materials and conditions: Relevance thresholds, individual changes and uncertainty
Materials to obtain first: Prior relevance thresholds, individual distributions, response definitions and persistence are unverified.
Further research: Material needed: Prior relevance thresholds, individual distributions, response definitions and persistence are unverified. This records needed materials; no new research was executed.
Remaining uncertainty: External original material is unread and review of existing content remains incomplete. Original grades, scores, axes, historical verification and independence statements are not treated as new verdicts or certification.
Conditions for verification: Material for Relevance thresholds, individual changes and uncertainty must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.
Why this condition is needed: This condition connects Relevance thresholds, individual changes and uncertainty with selected daytime sleepiness in moderate OSA, the structured program/wait list, the same paper/registration, respondents, ESS versus other endpoints, times, denominators and harms.
Application exceptions: Preserve original numbers, CIs, P values and study exposure only. Distinguish ESS points from AHI/h, PSQI and subjective bed-partner assessment; waiting from standard care; mean exposure from individual adherence; 25 completers from endpoint denominators; and the same paper/registration. Retrospective registration/historical checks do not become prerecruitment plans or current clinical review. No new arithmetic, effects, CIs, hypothetical numbers, grades, independence certification, playing/breathing methods, training, treatment-replacement or procedure instructions are created.
Referenced methods: Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.

Related sources S01

N11 · Did effects persist after four months?

Current findings: The original study assessed four months. Original statements that long-term complication prevention and standard-treatment replacement were not tested are preserved separately.
Verification status: Partly verified
Materials actually read: Stored summary read; external abstracts, full texts, registration, protocols, SAPs and support disclosures unread
Why unverified: The selected claim, parent material and reports are distinguished and transferred from the stored summary. Detailed original material is unverified and review of existing content remains incomplete. This does not establish completed clinical review or certification.
Reason for missing information: ESS persistence beyond four months, post-intervention changes and long-term clinical outcomes have no linked material.
Required materials and conditions: Assessment duration, intervention cessation and long-term follow-up
Materials to obtain first: ESS persistence beyond four months, post-intervention changes and long-term clinical outcomes have no linked material.
Further research: Material needed: ESS persistence beyond four months, post-intervention changes and long-term clinical outcomes have no linked material. This records needed materials; no new research was executed.
Remaining uncertainty: External original material is unread and review of existing content remains incomplete. Original grades, scores, axes, historical verification and independence statements are not treated as new verdicts or certification.
Conditions for verification: Material for Assessment duration, intervention cessation and long-term follow-up must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.
Why this condition is needed: This condition connects Assessment duration, intervention cessation and long-term follow-up with selected daytime sleepiness in moderate OSA, the structured program/wait list, the same paper/registration, respondents, ESS versus other endpoints, times, denominators and harms.
Application exceptions: Preserve original numbers, CIs, P values and study exposure only. Distinguish ESS points from AHI/h, PSQI and subjective bed-partner assessment; waiting from standard care; mean exposure from individual adherence; 25 completers from endpoint denominators; and the same paper/registration. Retrospective registration/historical checks do not become prerecruitment plans or current clinical review. No new arithmetic, effects, CIs, hypothetical numbers, grades, independence certification, playing/breathing methods, training, treatment-replacement or procedure instructions are created.
Referenced methods: Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.

Related sources S01

N12 · Is AHI a separate result from ESS?

Current findings: The AHI between-group difference of −6.2/h (−12.3 to −0.1, P=.05) is a separate sleep-study result. Its same-direction original signal is preserved without transfer to ESS effects/scores, cure or equivalence to standard therapy.
Verification status: Partly verified
Materials actually read: Stored summary read; external abstracts, full texts, registration, protocols, SAPs and support disclosures unread
Why unverified: The selected claim, parent material and reports are distinguished and transferred from the stored summary. Detailed original material is unverified and review of existing content remains incomplete. This does not establish completed clinical review or certification.
Reason for missing information: Sleep-study methods, AHI calculation, condition-specific denominators and exact prior analysis plans are unverified.
Required materials and conditions: Distinguishing ESS/AHI definitions, results and units
Materials to obtain first: Sleep-study methods, AHI calculation, condition-specific denominators and exact prior analysis plans are unverified.
Further research: Material needed: Sleep-study methods, AHI calculation, condition-specific denominators and exact prior analysis plans are unverified. This records needed materials; no new research was executed.
Remaining uncertainty: External original material is unread and review of existing content remains incomplete. Original grades, scores, axes, historical verification and independence statements are not treated as new verdicts or certification.
Conditions for verification: Material for Distinguishing ESS/AHI definitions, results and units must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.
Why this condition is needed: This condition connects Distinguishing ESS/AHI definitions, results and units with selected daytime sleepiness in moderate OSA, the structured program/wait list, the same paper/registration, respondents, ESS versus other endpoints, times, denominators and harms.
Application exceptions: Preserve original numbers, CIs, P values and study exposure only. Distinguish ESS points from AHI/h, PSQI and subjective bed-partner assessment; waiting from standard care; mean exposure from individual adherence; 25 completers from endpoint denominators; and the same paper/registration. Retrospective registration/historical checks do not become prerecruitment plans or current clinical review. No new arithmetic, effects, CIs, hypothetical numbers, grades, independence certification, playing/breathing methods, training, treatment-replacement or procedure instructions are created.
Referenced methods: Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.

Related sources S01

N13 · Is the null PSQI result also retained?

Current findings: PSQI −0.7 points (−2.1 to 0.6, P=.27) is described as null in the original. The sleepiness signal is not transferred to overall sleep-quality improvement, and nonsignificance does not become an exact zero effect.
Verification status: Partly verified
Materials actually read: Stored summary read; external abstracts, full texts, registration, protocols, SAPs and support disclosures unread
Why unverified: The selected claim, parent material and reports are distinguished and transferred from the stored summary. Detailed original material is unverified and review of existing content remains incomplete. This does not establish completed clinical review or certification.
Reason for missing information: PSQI procedures, denominators, model and prespecified hierarchy are unverified.
Required materials and conditions: Endpoint-specific effects, units and uncertainty
Materials to obtain first: PSQI procedures, denominators, model and prespecified hierarchy are unverified.
Further research: Material needed: PSQI procedures, denominators, model and prespecified hierarchy are unverified. This records needed materials; no new research was executed.
Remaining uncertainty: External original material is unread and review of existing content remains incomplete. Original grades, scores, axes, historical verification and independence statements are not treated as new verdicts or certification.
Conditions for verification: Material for Endpoint-specific effects, units and uncertainty must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.
Why this condition is needed: This condition connects Endpoint-specific effects, units and uncertainty with selected daytime sleepiness in moderate OSA, the structured program/wait list, the same paper/registration, respondents, ESS versus other endpoints, times, denominators and harms.
Application exceptions: Preserve original numbers, CIs, P values and study exposure only. Distinguish ESS points from AHI/h, PSQI and subjective bed-partner assessment; waiting from standard care; mean exposure from individual adherence; 25 completers from endpoint denominators; and the same paper/registration. Retrospective registration/historical checks do not become prerecruitment plans or current clinical review. No new arithmetic, effects, CIs, hypothetical numbers, grades, independence certification, playing/breathing methods, training, treatment-replacement or procedure instructions are created.
Referenced methods: Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.

Related sources S01

N14 · Are the bed-partner respondent and endpoint distinguished?

Current findings: The original describes a −2.8-point improvement in bed-partner sleep disturbance as subjective assessment. It is not transferred to patient ESS, objective AHI or direct replication in an independent trial.
Verification status: Partly verified
Materials actually read: Stored summary read; external abstracts, full texts, registration, protocols, SAPs and support disclosures unread
Why unverified: The selected claim, parent material and reports are distinguished and transferred from the stored summary. Detailed original material is unverified and review of existing content remains incomplete. This does not establish completed clinical review or certification.
Reason for missing information: Bed-partner denominators, scale, exact CIs/P values, masking and prior hierarchy are unverified.
Required materials and conditions: Respondent, scale, endpoint and denominators
Materials to obtain first: Bed-partner denominators, scale, exact CIs/P values, masking and prior hierarchy are unverified.
Further research: Material needed: Bed-partner denominators, scale, exact CIs/P values, masking and prior hierarchy are unverified. This records needed materials; no new research was executed.
Remaining uncertainty: External original material is unread and review of existing content remains incomplete. Original grades, scores, axes, historical verification and independence statements are not treated as new verdicts or certification.
Conditions for verification: Material for Respondent, scale, endpoint and denominators must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.
Why this condition is needed: This condition connects Respondent, scale, endpoint and denominators with selected daytime sleepiness in moderate OSA, the structured program/wait list, the same paper/registration, respondents, ESS versus other endpoints, times, denominators and harms.
Application exceptions: Preserve original numbers, CIs, P values and study exposure only. Distinguish ESS points from AHI/h, PSQI and subjective bed-partner assessment; waiting from standard care; mean exposure from individual adherence; 25 completers from endpoint denominators; and the same paper/registration. Retrospective registration/historical checks do not become prerecruitment plans or current clinical review. No new arithmetic, effects, CIs, hypothetical numbers, grades, independence certification, playing/breathing methods, training, treatment-replacement or procedure instructions are created.
Referenced methods: Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.

Related sources S01

N15 · Does completion by everyone establish every analysis denominator?

Current findings: The original records all 25 participants completing follow-up. This does not automatically fill arm n, complete ESS/AHI/PSQI analyses or ITT/PP status.
Verification status: Partly verified
Materials actually read: Stored summary read; external abstracts, full texts, registration, protocols, SAPs and support disclosures unread
Why unverified: The selected claim, parent material and reports are distinguished and transferred from the stored summary. Detailed original material is unverified and review of existing content remains incomplete. This does not establish completed clinical review or certification.
Reason for missing information: Arm allocation, endpoint analysis denominators, missingness, ITT/PP and exclusion reasons are unverified.
Required materials and conditions: Allocation, completion, endpoint analyses and missingness
Materials to obtain first: Arm allocation, endpoint analysis denominators, missingness, ITT/PP and exclusion reasons are unverified.
Further research: Material needed: Arm allocation, endpoint analysis denominators, missingness, ITT/PP and exclusion reasons are unverified. This records needed materials; no new research was executed.
Remaining uncertainty: External original material is unread and review of existing content remains incomplete. Original grades, scores, axes, historical verification and independence statements are not treated as new verdicts or certification.
Conditions for verification: Material for Allocation, completion, endpoint analyses and missingness must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.
Why this condition is needed: This condition connects Allocation, completion, endpoint analyses and missingness with selected daytime sleepiness in moderate OSA, the structured program/wait list, the same paper/registration, respondents, ESS versus other endpoints, times, denominators and harms.
Application exceptions: Preserve original numbers, CIs, P values and study exposure only. Distinguish ESS points from AHI/h, PSQI and subjective bed-partner assessment; waiting from standard care; mean exposure from individual adherence; 25 completers from endpoint denominators; and the same paper/registration. Retrospective registration/historical checks do not become prerecruitment plans or current clinical review. No new arithmetic, effects, CIs, hypothetical numbers, grades, independence certification, playing/breathing methods, training, treatment-replacement or procedure instructions are created.
Referenced methods: Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.

Related sources S01

N16 · Are concurrent treatment, weight and lifestyle changes verified?

Current findings: The comparison is lessons/home practice versus waiting. The summary is not extended to certify control or absence of concurrent OSA therapy, weight changes or lifestyle changes.
Verification status: Unverified
Materials actually read: Stored summary read; external abstracts, full texts, registration, protocols, SAPs and support disclosures unread
Why unverified: The selected claim, parent material and reports are distinguished and transferred from the stored summary. Detailed original material is unverified and review of existing content remains incomplete. This does not establish completed clinical review or certification.
Reason for missing information: Concurrent therapy, weight/activity changes, medication, baseline adjustment and adherence are unverified.
Required materials and conditions: Arm-specific concurrent care, exposure and adjustment
Materials to obtain first: Concurrent therapy, weight/activity changes, medication, baseline adjustment and adherence are unverified.
Further research: Material needed: Concurrent therapy, weight/activity changes, medication, baseline adjustment and adherence are unverified. This records needed materials; no new research was executed.
Remaining uncertainty: External original material is unread and review of existing content remains incomplete. Original grades, scores, axes, historical verification and independence statements are not treated as new verdicts or certification.
Conditions for verification: Material for Arm-specific concurrent care, exposure and adjustment must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.
Why this condition is needed: This condition connects Arm-specific concurrent care, exposure and adjustment with selected daytime sleepiness in moderate OSA, the structured program/wait list, the same paper/registration, respondents, ESS versus other endpoints, times, denominators and harms.
Application exceptions: Preserve original numbers, CIs, P values and study exposure only. Distinguish ESS points from AHI/h, PSQI and subjective bed-partner assessment; waiting from standard care; mean exposure from individual adherence; 25 completers from endpoint denominators; and the same paper/registration. Retrospective registration/historical checks do not become prerecruitment plans or current clinical review. No new arithmetic, effects, CIs, hypothetical numbers, grades, independence certification, playing/breathing methods, training, treatment-replacement or procedure instructions are created.
Referenced methods: Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.

Related sources S01

N17 · When was ISRCTN registration made?

Current findings: The preserved registration is ISRCTN31571714; the original records registration after recruitment began. Its identifier/URL does not establish current registration reading or verification of prerecruitment registration.
Verification status: Partly verified
Materials actually read: Stored summary read; external abstracts, full texts, registration, protocols, SAPs and support disclosures unread
Why unverified: The selected claim, parent material and reports are distinguished and transferred from the stored summary. Detailed original material is unverified and review of existing content remains incomplete. This does not establish completed clinical review or certification.
Reason for missing information: Exact recruitment/registration dates, original registration and change-history details remain unread.
Required materials and conditions: Registration identity, recruitment/registration timing and original records
Materials to obtain first: Exact recruitment/registration dates, original registration and change-history details remain unread.
Further research: Material needed: Exact recruitment/registration dates, original registration and change-history details remain unread. This records needed materials; no new research was executed.
Remaining uncertainty: External original material is unread and review of existing content remains incomplete. Original grades, scores, axes, historical verification and independence statements are not treated as new verdicts or certification.
Conditions for verification: Material for Registration identity, recruitment/registration timing and original records must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.
Why this condition is needed: This condition connects Registration identity, recruitment/registration timing and original records with selected daytime sleepiness in moderate OSA, the structured program/wait list, the same paper/registration, respondents, ESS versus other endpoints, times, denominators and harms.
Application exceptions: Preserve original numbers, CIs, P values and study exposure only. Distinguish ESS points from AHI/h, PSQI and subjective bed-partner assessment; waiting from standard care; mean exposure from individual adherence; 25 completers from endpoint denominators; and the same paper/registration. Retrospective registration/historical checks do not become prerecruitment plans or current clinical review. No new arithmetic, effects, CIs, hypothetical numbers, grades, independence certification, playing/breathing methods, training, treatment-replacement or procedure instructions are created.
Referenced methods: Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.

Related sources S01 S02

N18 · Does an ESS main endpoint establish the complete prior plan?

Current findings: The original evidence item records four-month ESS as the main endpoint; historical grading describes separation of ESS/AHI/PSQI. In the retrospective-registration context, this is not converted into verified prerecruitment hierarchy or a completely reviewed SAP.
Verification status: Partly verified
Materials actually read: Stored summary read; external abstracts, full texts, registration, protocols, SAPs and support disclosures unread
Why unverified: The selected claim, parent material and reports are distinguished and transferred from the stored summary. Detailed original material is unverified and review of existing content remains incomplete. This does not establish completed clinical review or certification.
Reason for missing information: Prerecruitment ESS hierarchy, protocol, SAP, change history and analysis plans are unverified.
Required materials and conditions: Separating main-endpoint wording, registration, protocol and SAP
Materials to obtain first: Prerecruitment ESS hierarchy, protocol, SAP, change history and analysis plans are unverified.
Further research: Material needed: Prerecruitment ESS hierarchy, protocol, SAP, change history and analysis plans are unverified. This records needed materials; no new research was executed.
Remaining uncertainty: External original material is unread and review of existing content remains incomplete. Original grades, scores, axes, historical verification and independence statements are not treated as new verdicts or certification.
Conditions for verification: Material for Separating main-endpoint wording, registration, protocol and SAP must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.
Why this condition is needed: This condition connects Separating main-endpoint wording, registration, protocol and SAP with selected daytime sleepiness in moderate OSA, the structured program/wait list, the same paper/registration, respondents, ESS versus other endpoints, times, denominators and harms.
Application exceptions: Preserve original numbers, CIs, P values and study exposure only. Distinguish ESS points from AHI/h, PSQI and subjective bed-partner assessment; waiting from standard care; mean exposure from individual adherence; 25 completers from endpoint denominators; and the same paper/registration. Retrospective registration/historical checks do not become prerecruitment plans or current clinical review. No new arithmetic, effects, CIs, hypothetical numbers, grades, independence certification, playing/breathing methods, training, treatment-replacement or procedure instructions are created.
Referenced methods: Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.

Related sources S01 S02

N19 · Are multiple endpoints and test models distinguished?

Current findings: ESS, AHI, PSQI and subjective bed-partner assessment are different results. Some significant results are not extended to success of all endpoints or prior multiplicity adjustment.
Verification status: Unverified
Materials actually read: Stored summary read; external abstracts, full texts, registration, protocols, SAPs and support disclosures unread
Why unverified: The selected claim, parent material and reports are distinguished and transferred from the stored summary. Detailed original material is unverified and review of existing content remains incomplete. This does not establish completed clinical review or certification.
Reason for missing information: Test direction, exact models, covariates, multiplicity and prior plans for additional endpoints are unverified.
Required materials and conditions: All endpoints, tests, adjustment and multiplicity
Materials to obtain first: Test direction, exact models, covariates, multiplicity and prior plans for additional endpoints are unverified.
Further research: Material needed: Test direction, exact models, covariates, multiplicity and prior plans for additional endpoints are unverified. This records needed materials; no new research was executed.
Remaining uncertainty: External original material is unread and review of existing content remains incomplete. Original grades, scores, axes, historical verification and independence statements are not treated as new verdicts or certification.
Conditions for verification: Material for All endpoints, tests, adjustment and multiplicity must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.
Why this condition is needed: This condition connects All endpoints, tests, adjustment and multiplicity with selected daytime sleepiness in moderate OSA, the structured program/wait list, the same paper/registration, respondents, ESS versus other endpoints, times, denominators and harms.
Application exceptions: Preserve original numbers, CIs, P values and study exposure only. Distinguish ESS points from AHI/h, PSQI and subjective bed-partner assessment; waiting from standard care; mean exposure from individual adherence; 25 completers from endpoint denominators; and the same paper/registration. Retrospective registration/historical checks do not become prerecruitment plans or current clinical review. No new arithmetic, effects, CIs, hypothetical numbers, grades, independence certification, playing/breathing methods, training, treatment-replacement or procedure instructions are created.
Referenced methods: Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.

Related sources S01

N20 · Are the paper and registration separate trials?

Current findings: The S01 Puhan 2006 paper and S02 ISRCTN31571714 registration are preserved links to the same 25-person four-month trial. Registration is not counted as another sleepiness-effect report, new participants or an independent trial.
Verification status: Partly verified
Materials actually read: Stored summary read; external abstracts, full texts, registration, protocols, SAPs and support disclosures unread
Why unverified: The selected claim, parent material and reports are distinguished and transferred from the stored summary. Detailed original material is unverified and review of existing content remains incomplete. This does not establish completed clinical review or certification.
Reason for missing information: Detailed original/registration plans and correspondence between analyses remain externally unread.
Required materials and conditions: Reports, registration, trial family and population links
Materials to obtain first: Detailed original/registration plans and correspondence between analyses remain externally unread.
Further research: Material needed: Detailed original/registration plans and correspondence between analyses remain externally unread. This records needed materials; no new research was executed.
Remaining uncertainty: External original material is unread and review of existing content remains incomplete. Original grades, scores, axes, historical verification and independence statements are not treated as new verdicts or certification.
Conditions for verification: Material for Reports, registration, trial family and population links must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.
Why this condition is needed: This condition connects Reports, registration, trial family and population links with selected daytime sleepiness in moderate OSA, the structured program/wait list, the same paper/registration, respondents, ESS versus other endpoints, times, denominators and harms.
Application exceptions: Preserve original numbers, CIs, P values and study exposure only. Distinguish ESS points from AHI/h, PSQI and subjective bed-partner assessment; waiting from standard care; mean exposure from individual adherence; 25 completers from endpoint denominators; and the same paper/registration. Retrospective registration/historical checks do not become prerecruitment plans or current clinical review. No new arithmetic, effects, CIs, hypothetical numbers, grades, independence certification, playing/breathing methods, training, treatment-replacement or procedure instructions are created.
Referenced methods: Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.

Related sources S01 S02

N21 · Was the sleepiness effect independently replicated?

Current findings: The stored report states that independent replication was absent. Multiple endpoints, paper/registration and two subclaim sheets from one trial do not become independent replication.
Verification status: Unverified
Materials actually read: Stored summary read; external abstracts, full texts, registration, protocols, SAPs and support disclosures unread
Why unverified: The selected claim, parent material and reports are distinguished and transferred from the stored summary. Detailed original material is unverified and review of existing content remains incomplete. This does not establish completed clinical review or certification.
Reason for missing information: Separate replication under the same conditions and actual trial-family independence are unverified.
Required materials and conditions: Separate trials with the same population/intervention/comparator
Materials to obtain first: Separate replication under the same conditions and actual trial-family independence are unverified.
Further research: Material needed: Separate replication under the same conditions and actual trial-family independence are unverified. This records needed materials; no new research was executed.
Remaining uncertainty: External original material is unread and review of existing content remains incomplete. Original grades, scores, axes, historical verification and independence statements are not treated as new verdicts or certification.
Conditions for verification: Material for Separate trials with the same population/intervention/comparator must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.
Why this condition is needed: This condition connects Separate trials with the same population/intervention/comparator with selected daytime sleepiness in moderate OSA, the structured program/wait list, the same paper/registration, respondents, ESS versus other endpoints, times, denominators and harms.
Application exceptions: Preserve original numbers, CIs, P values and study exposure only. Distinguish ESS points from AHI/h, PSQI and subjective bed-partner assessment; waiting from standard care; mean exposure from individual adherence; 25 completers from endpoint denominators; and the same paper/registration. Retrospective registration/historical checks do not become prerecruitment plans or current clinical review. No new arithmetic, effects, CIs, hypothetical numbers, grades, independence certification, playing/breathing methods, training, treatment-replacement or procedure instructions are created.
Referenced methods: Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.

Related sources S01 S02

N22 · Does this apply to other BMIs, severities or ages?

Current findings: The direct population is selected adults with BMI below 30 and AHI 15–30/h. The same effects are not generalized to other severities, BMIs, ages or diseases.
Verification status: Unverified
Materials actually read: Stored summary read; external abstracts, full texts, registration, protocols, SAPs and support disclosures unread
Why unverified: The selected claim, parent material and reports are distinguished and transferred from the stored summary. Detailed original material is unverified and review of existing content remains incomplete. This does not establish completed clinical review or certification.
Reason for missing information: Population-specific ESS, AHI, safety and prior subgroup plans have no linked material.
Required materials and conditions: Direct population-specific material and subgroup plans
Materials to obtain first: Population-specific ESS, AHI, safety and prior subgroup plans have no linked material.
Further research: Material needed: Population-specific ESS, AHI, safety and prior subgroup plans have no linked material. This records needed materials; no new research was executed.
Remaining uncertainty: External original material is unread and review of existing content remains incomplete. Original grades, scores, axes, historical verification and independence statements are not treated as new verdicts or certification.
Conditions for verification: Material for Direct population-specific material and subgroup plans must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.
Why this condition is needed: This condition connects Direct population-specific material and subgroup plans with selected daytime sleepiness in moderate OSA, the structured program/wait list, the same paper/registration, respondents, ESS versus other endpoints, times, denominators and harms.
Application exceptions: Preserve original numbers, CIs, P values and study exposure only. Distinguish ESS points from AHI/h, PSQI and subjective bed-partner assessment; waiting from standard care; mean exposure from individual adherence; 25 completers from endpoint denominators; and the same paper/registration. Retrospective registration/historical checks do not become prerecruitment plans or current clinical review. No new arithmetic, effects, CIs, hypothetical numbers, grades, independence certification, playing/breathing methods, training, treatment-replacement or procedure instructions are created.
Referenced methods: Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.

Related sources S01

N23 · Do sleepiness/AHI signals establish replacement of standard therapy?

Current findings: The parent report describes a wait-list signal and states that noninferiority/replacement versus CPAP or oral appliances was not tested. Sleepiness results do not establish equal standard-treatment effects, cure or grounds to stop treatment.
Verification status: Partly verified
Materials actually read: Stored summary read; external abstracts, full texts, registration, protocols, SAPs and support disclosures unread
Why unverified: The selected claim, parent material and reports are distinguished and transferred from the stored summary. Detailed original material is unverified and review of existing content remains incomplete. This does not establish completed clinical review or certification.
Reason for missing information: Direct standard-treatment comparisons, noninferiority and long-term clinical outcomes have no linked material.
Required materials and conditions: Direct standard-treatment comparisons and clinical outcomes
Materials to obtain first: Direct standard-treatment comparisons, noninferiority and long-term clinical outcomes have no linked material.
Further research: Material needed: Direct standard-treatment comparisons, noninferiority and long-term clinical outcomes have no linked material. This records needed materials; no new research was executed.
Remaining uncertainty: External original material is unread and review of existing content remains incomplete. Original grades, scores, axes, historical verification and independence statements are not treated as new verdicts or certification.
Conditions for verification: Material for Direct standard-treatment comparisons and clinical outcomes must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.
Why this condition is needed: This condition connects Direct standard-treatment comparisons and clinical outcomes with selected daytime sleepiness in moderate OSA, the structured program/wait list, the same paper/registration, respondents, ESS versus other endpoints, times, denominators and harms.
Application exceptions: Preserve original numbers, CIs, P values and study exposure only. Distinguish ESS points from AHI/h, PSQI and subjective bed-partner assessment; waiting from standard care; mean exposure from individual adherence; 25 completers from endpoint denominators; and the same paper/registration. Retrospective registration/historical checks do not become prerecruitment plans or current clinical review. No new arithmetic, effects, CIs, hypothetical numbers, grades, independence certification, playing/breathing methods, training, treatment-replacement or procedure instructions are created.
Referenced methods: Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.

Related sources S01 S02

N24 · Are funding, the developer-instructor and conflicts distinguished?

Current findings: Original funding records Zurich Lung Association/clinical support and a training developer-instructor among the authors. This is not converted into complete conflict verification or independence certification.
Verification status: Partly verified
Materials actually read: Stored summary read; external abstracts, full texts, registration, protocols, SAPs and support disclosures unread
Why unverified: The selected claim, parent material and reports are distinguished and transferred from the stored summary. Detailed original material is unverified and review of existing content remains incomplete. This does not establish completed clinical review or certification.
Reason for missing information: Funding roles, equipment/instrument support, developer-instructor roles, employee authors, COI and analysis/reporting involvement are unverified.
Required materials and conditions: Original support, product, employee/developer and COI records
Materials to obtain first: Funding roles, equipment/instrument support, developer-instructor roles, employee authors, COI and analysis/reporting involvement are unverified.
Further research: Material needed: Funding roles, equipment/instrument support, developer-instructor roles, employee authors, COI and analysis/reporting involvement are unverified. This records needed materials; no new research was executed.
Remaining uncertainty: External original material is unread and review of existing content remains incomplete. Original grades, scores, axes, historical verification and independence statements are not treated as new verdicts or certification.
Conditions for verification: Material for Original support, product, employee/developer and COI records must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.
Why this condition is needed: This condition connects Original support, product, employee/developer and COI records with selected daytime sleepiness in moderate OSA, the structured program/wait list, the same paper/registration, respondents, ESS versus other endpoints, times, denominators and harms.
Application exceptions: Preserve original numbers, CIs, P values and study exposure only. Distinguish ESS points from AHI/h, PSQI and subjective bed-partner assessment; waiting from standard care; mean exposure from individual adherence; 25 completers from endpoint denominators; and the same paper/registration. Retrospective registration/historical checks do not become prerecruitment plans or current clinical review. No new arithmetic, effects, CIs, hypothetical numbers, grades, independence certification, playing/breathing methods, training, treatment-replacement or procedure instructions are created.
Referenced methods: Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.

Related sources S01

N25 · What was reported about safety and sample-size limits?

Current findings: The original parent safety label is Good; no unexpected/adverse events were reported in 25 people over four months. This is not extended to absence of rare harms, long-term safety or safety of stopping established treatment.
Verification status: Partly verified
Materials actually read: Stored summary read; external abstracts, full texts, registration, protocols, SAPs and support disclosures unread
Why unverified: The selected claim, parent material and reports are distinguished and transferred from the stored summary. Detailed original material is unverified and review of existing content remains incomplete. This does not establish completed clinical review or certification.
Reason for missing information: Collection methods, event definitions, arm denominators, rare/long-term harms and treatment-cessation material are unverified.
Required materials and conditions: Harm collection, exposure, arm denominators and follow-up
Materials to obtain first: Collection methods, event definitions, arm denominators, rare/long-term harms and treatment-cessation material are unverified.
Further research: Material needed: Collection methods, event definitions, arm denominators, rare/long-term harms and treatment-cessation material are unverified. This records needed materials; no new research was executed.
Remaining uncertainty: External original material is unread and review of existing content remains incomplete. Original grades, scores, axes, historical verification and independence statements are not treated as new verdicts or certification.
Conditions for verification: Material for Harm collection, exposure, arm denominators and follow-up must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.
Why this condition is needed: This condition connects Harm collection, exposure, arm denominators and follow-up with selected daytime sleepiness in moderate OSA, the structured program/wait list, the same paper/registration, respondents, ESS versus other endpoints, times, denominators and harms.
Application exceptions: Preserve original numbers, CIs, P values and study exposure only. Distinguish ESS points from AHI/h, PSQI and subjective bed-partner assessment; waiting from standard care; mean exposure from individual adherence; 25 completers from endpoint denominators; and the same paper/registration. Retrospective registration/historical checks do not become prerecruitment plans or current clinical review. No new arithmetic, effects, CIs, hypothetical numbers, grades, independence certification, playing/breathing methods, training, treatment-replacement or procedure instructions are created.
Referenced methods: Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.

Related sources S01

N26 · Are parent values, subclaim grade and the evidence date separated?

Current findings: Parent C50, B/P/R1/I1/E+/B2/CX, four false flags, empty override and subclaim C/note are preserved. Original bilingual wording, 2026-09-07, empty corrections array and empty deliberation string are not inherited as the current review date or a subclaim score.
Verification status: Partly verified
Materials actually read: Stored summary read; external abstracts, full texts, registration, protocols, SAPs and support disclosures unread
Why unverified: The selected claim, parent material and reports are distinguished and transferred from the stored summary. Detailed original material is unverified and review of existing content remains incomplete. This does not establish completed clinical review or certification.
Reason for missing information: Subclaim score, status and axes are absent from the original. New corrections and external original-text comparisons were not performed.
Required materials and conditions: Parent/subclaim original values and historical dates
Materials to obtain first: Subclaim score, status and axes are absent from the original. New corrections and external original-text comparisons were not performed.
Further research: Material needed: Subclaim score, status and axes are absent from the original. New corrections and external original-text comparisons were not performed. This records needed materials; no new research was executed.
Remaining uncertainty: External original material is unread and review of existing content remains incomplete. Original grades, scores, axes, historical verification and independence statements are not treated as new verdicts or certification.
Conditions for verification: Material for Parent/subclaim original values and historical dates must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.
Why this condition is needed: This condition connects Parent/subclaim original values and historical dates with selected daytime sleepiness in moderate OSA, the structured program/wait list, the same paper/registration, respondents, ESS versus other endpoints, times, denominators and harms.
Application exceptions: Preserve original numbers, CIs, P values and study exposure only. Distinguish ESS points from AHI/h, PSQI and subjective bed-partner assessment; waiting from standard care; mean exposure from individual adherence; 25 completers from endpoint denominators; and the same paper/registration. Retrospective registration/historical checks do not become prerecruitment plans or current clinical review. No new arithmetic, effects, CIs, hypothetical numbers, grades, independence certification, playing/breathing methods, training, treatment-replacement or procedure instructions are created.
Referenced methods: Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.

Related sources S01 S02

N27 · Are historical checks the current reading?

Current findings: Original primary-trial, ISRCTN and effect-size verification is preserved as historical wording. Stored summaries/bibliography were used here; original papers, registration, protocols, SAPs and COI remain unread without access attempts.
Verification status: Partly verified
Materials actually read: Stored summary read; external abstracts, full texts, registration, protocols, SAPs and support disclosures unread
Why unverified: The selected claim, parent material and reports are distinguished and transferred from the stored summary. Detailed original material is unverified and review of existing content remains incomplete. This does not establish completed clinical review or certification.
Reason for missing information: Historical-check details, current external-original acquisition/reading and content review remain incomplete.
Required materials and conditions: Historical review statements, summary use and external access
Materials to obtain first: Historical-check details, current external-original acquisition/reading and content review remain incomplete.
Further research: Material needed: Historical-check details, current external-original acquisition/reading and content review remain incomplete. This records needed materials; no new research was executed.
Remaining uncertainty: External original material is unread and review of existing content remains incomplete. Original grades, scores, axes, historical verification and independence statements are not treated as new verdicts or certification.
Conditions for verification: Material for Historical review statements, summary use and external access must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.
Why this condition is needed: This condition connects Historical review statements, summary use and external access with selected daytime sleepiness in moderate OSA, the structured program/wait list, the same paper/registration, respondents, ESS versus other endpoints, times, denominators and harms.
Application exceptions: Preserve original numbers, CIs, P values and study exposure only. Distinguish ESS points from AHI/h, PSQI and subjective bed-partner assessment; waiting from standard care; mean exposure from individual adherence; 25 completers from endpoint denominators; and the same paper/registration. Retrospective registration/historical checks do not become prerecruitment plans or current clinical review. No new arithmetic, effects, CIs, hypothetical numbers, grades, independence certification, playing/breathing methods, training, treatment-replacement or procedure instructions are created.
Referenced methods: Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.

Related sources S01 S02

N28 · Which materials would trigger an update?

Current findings: Original paper/ISRCTN URLs are retained and actual reading is distinguished as summary read versus external material unread. URL presence alone does not raise verification status.
Verification status: Partly verified
Materials actually read: Stored summary read; external abstracts, full texts, registration, protocols, SAPs and support disclosures unread
Why unverified: The selected claim, parent material and reports are distinguished and transferred from the stored summary. Detailed original material is unverified and review of existing content remains incomplete. This does not establish completed clinical review or certification.
Reason for missing information: External-original acquisition, reading, URL verification and content review are needed. Complete pre-change originals, material/condition versions, separate application and change history must be retained.
Required materials and conditions: Linking summary reading, unread originals and needed material
Materials to obtain first: External-original acquisition, reading, URL verification and content review are needed. Complete pre-change originals, material/condition versions, separate application and change history must be retained.
Further research: Material needed: External-original acquisition, reading, URL verification and content review are needed. Complete pre-change originals, material/condition versions, separate application and change history must be retained. This records needed materials; no new research was executed.
Remaining uncertainty: External original material is unread and review of existing content remains incomplete. Original grades, scores, axes, historical verification and independence statements are not treated as new verdicts or certification.
Conditions for verification: Material for Linking summary reading, unread originals and needed material must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.
Why this condition is needed: This condition connects Linking summary reading, unread originals and needed material with selected daytime sleepiness in moderate OSA, the structured program/wait list, the same paper/registration, respondents, ESS versus other endpoints, times, denominators and harms.
Application exceptions: Preserve original numbers, CIs, P values and study exposure only. Distinguish ESS points from AHI/h, PSQI and subjective bed-partner assessment; waiting from standard care; mean exposure from individual adherence; 25 completers from endpoint denominators; and the same paper/registration. Retrospective registration/historical checks do not become prerecruitment plans or current clinical review. No new arithmetic, effects, CIs, hypothetical numbers, grades, independence certification, playing/breathing methods, training, treatment-replacement or procedure instructions are created.
Referenced methods: Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.

Related sources S01 S02