Non-obligatory postcards × people with any repetition: an evidence sheet distinguishing repeat-event counts

Required evidence, verification status and materials actually read
Item	AVerification status	BReading scope	CReview item	DCurrent findings	EWhy unverified	FRequired materials and conditions	GFurther research
1	Partly verified	Full text not readStored summary read	N01 · Comparative efficacyAre the selected reduction in people with any repetition and the parent repeat-event result distinguished?Required	The selected original question is ‘Fewer people with any repetition’, with original grade D and a note describing 15.1% versus 17.3% and a CI including zero. The parent verdict concerns fewer repeat events, grade C, 56 points and unknown safety. R01	Only the relevant information from the stored summary is recorded. Detailed original materials have not been read, and the original content review remains incomplete. Missing subclaim score, status and axes are not filled with the parent score. No new verdict is made.	Separate records of the original subclaim, grade, note and parent results	Additional materials are linked separately to the selected any-repetition endpoint and the repeat-event endpoint.
2	Partly verified	Full text not readStored summary read	N02 · Comparative efficacyWho was recruited after hospital treatment and what is the scope of application?Required	The recorded study population comprises 772 participants aged 16 or older after hospital treatment in Newcastle, Australia. R01	Only the relevant information from the stored summary is recorded. Detailed original materials have not been read, and the original content review remains incomplete. The results are not automatically applied to other locations, ages, prior treatments or episode types. Detailed eligibility, baseline characteristics and histories of previous repetition have not been read.	Prior episodes, age, location, eligibility, baseline characteristics and denominators	Obtain original eligibility, baseline characteristics, individual histories of repetition and treatment records.
3	Partly verified	Full text not readStored summary read	N03 · Comparative efficacyAre non-obligatory postcard exposure and the existing-treatment comparator distinguished?Required	The original intervention consisted of 8 postcards requiring no reply over 12 months; the comparator was usual care. R01	Only the relevant information from the stored summary is recorded. Detailed original materials have not been read, and the original content review remains incomplete. Detailed mailing times, wording, actual receipt, existing treatment and additional care have not been read. No personal support actions, treatment or implementation instructions are created.	Records of historical study exposure, usual care and concomitant care by group	Obtain original intervention, actual exposure, usual-care and concomitant-care materials.
4	Partly verified	Full text not readStored summary read	N04 · Comparative efficacyAre the units of randomized people, people with repetition and repeat events preserved separately?Required	Among 772 participants, 378 were assigned to postcards and 394 to usual care. People with any repetition and total events are different units. R01	Only the relevant information from the stored summary is recorded. Detailed original materials have not been read, and the original content review remains incomplete. Events are not converted into people, and people with repetition are not added as new participants. The same participants in sibling sheets are not added together.	Distinguishing randomized denominators, individual repetition and event counts	Obtain original mappings of person-level and event-level analyses and follow-up denominators.
5	Partly verified	Full text not readStored summary read	N05 · Comparative efficacyWhat are the definition, follow-up period and ascertainment scope for people with any repetition?Required	The preserved record states that the trial counted hospital-treated episodes through an administrative database over 12 months. R01	Only the relevant information from the stored summary is recorded. Detailed original materials have not been read, and the original content review remains incomplete. Episodes outside hospital, episodes at other institutions, self-reports and deaths are not assigned the same repetition definition. Detailed capture scope and linkage omissions have not been read.	Episode definition, hospital treatment, follow-up period and administrative-data scope	Obtain original episode definitions, database, linkage, observation-period and missing-data materials.
6	Partly verified	Full text not readStored summary read	N06 · Comparative efficacyAre 57/378 versus 68/394 and the proportions preserved as originally recorded?Required	People with any repetition numbered 57/378 (15.1%) in the postcard group versus 68/394 (17.3%) with usual care. R01	Only the relevant information from the stored summary is recorded. Detailed original materials have not been read, and the original content review remains incomplete. Proportions are not recalculated, and new person counts, missing denominators or repetition rates are not created.	People with repetition by group, original denominators, proportions and analysis populations	Obtain original person-level episode tables, group denominators, follow-up completeness and analysis populations.
7	Partly verified	Full text not readStored summary read	N07 · Comparative efficacyAre the difference in repeater proportions, its interval and the missing P value preserved?Required	The stored summary records a difference of −2 percentage points (95% CI −7 to 3) and judges the repeater result null. R01	Only the relevant information from the stored summary is recorded. Detailed original materials have not been read, and the original content review remains incomplete. P values, RR, OR, NNT or new risk differences absent from the original record are not calculated. An interval including zero does not certify every effect as zero or establish equivalence.	Original between-group difference, interval, test, denominators and model	Link original tests, models, intervals, prespecified importance thresholds and denominator materials.
8	Partly verified	Full text not readStored summary read	N08 · Comparative efficacyDo 101 versus 192 repeat events and the IRR describe the selected effect on people with repetition?Required	Total repeat events fell to 101 versus 192, IRR 0.55 (95% CI 0.35–0.87). R01	Only the relevant information from the stored summary is recorded. Detailed original materials have not been read, and the original content review remains incomplete. Fewer events are not repurposed as fewer people with repetition or confirmed prevention. Person-level distributions, exposure time and models have not been read.	Separate records of event counts, person counts, exposure time and incidence rate ratio	Obtain individual repetition distributions, original event tables, exposure and incidence-rate analysis plans.
9	Partly verified	Full text not readStored summary read	N09 · Comparative efficacyAre total events, repeat events per person and the contribution of a small group of repeaters distinguished?Required	The original text explains that only repeated episodes among a small group declined; the recorded endpoints include repeat events per person. R01	Only the relevant information from the stored summary is recorded. Detailed original materials have not been read, and the original content review remains incomplete. Mean event counts, high-frequency subgroup sizes, distributions and sample-specific effects are not newly calculated. The original explanation is not relabelled as a completed subgroup test.	Original data on event distributions, individual repetition, observation time and models	Obtain original person-level distributions, repeated-event models, subgroup plans and denominators.
10	Partly verified	Full text not readStored summary read	N10 · Comparative efficacyAre the split coprimary outcomes and selected subclaim grade D displayed together?Required	The original materials record repeater proportion and repeat-event count as coprimary outcomes, with only one succeeding. The original axis flag for split coprimary outcomes is preserved as true. R01	Only the relevant information from the stored summary is recorded. Detailed original materials have not been read, and the original content review remains incomplete. Success on event count is not retained while failure on repeater proportion is omitted, and parent grade C is not transferred to the selected endpoint. Detailed testing and adjustment plans have not been read.	Coprimary designation, individual effects, tests and multiplicity plans	Obtain original protocols, SAP, coprimary endpoint hierarchy, multiplicity plans and individual original tables.
11	Partly verified	Full text not readStored summary read	N11 · Comparative efficacyWhat is the recorded information on randomization, concealment, blinding and administrative measurement?Required	The stored summary describes a randomized usual-care-controlled trial with unavoidable participant unblinding, while hospital administrative data were used to count episodes. R01	Only the relevant information from the stored summary is recorded. Detailed original materials have not been read, and the original content review remains incomplete. Using administrative data does not certify that all measurement, capture or selection bias was resolved. Allocation-concealment and analyst procedures have not been read.	Allocation, concealment, participant/outcome measurement and analyst procedures	Obtain original methods, administrative linkage, allocation, concealment, measurement and analysis procedures.
12	Unverified	Full text not readStored summary read	N12 · Comparative efficacyDo gaps remain in 12-month follow-up, missing data, deaths, relocation and analysis populations?Required	Randomized denominators, the 12-month period and administrative counting are preserved. R01	Only the relevant information from the stored summary is recorded. Detailed original materials have not been read, and the original content review remains incomplete. Reporting denominators does not establish complete follow-up for everyone. Detailed handling of withdrawals, relocation and deaths, and ITT procedures, have not been read.	Follow-up by group, reasons for missing data, competing events, analysis populations and sensitivity analyses	Obtain original follow-up flows, administrative capture, analysis populations and missing-data/competing-event plans.
13	Unverified	Full text not readStored summary read	N13 · Comparative efficacyCan actual postcard receipt, replies, existing treatment exposure and adherence be verified?Required	Historical exposure to postcards requiring no reply and the usual-care comparator are recorded. R01	Only the relevant information from the stored summary is recorded. Detailed original materials have not been read, and the original content review remains incomplete. Not requiring replies does not mean receipt, contact or treatment use was equal. Numbers received, discontinuation, treatment changes and effect mappings have not been read.	Actual study exposure, receipt, discontinuation, treatment use and concomitant treatment records	Obtain actual exposure, receipt, existing treatment, discontinuation and prespecified effects of interest.
14	Partly verified	Full text not readStored summary read	N14 · Comparative efficacyAre prespecified plans and the registration identifier distinguished from actual reading of the registration?Required	The original recorded registration string is ACTRN012605000050651. Coprimary designation is preserved in the parent text. R01	Only the relevant information from the stored summary is recorded. Detailed original materials have not been read, and the original content review remains incomplete. The identifier is not arbitrarily corrected and no new URL is constructed. External registration, protocol and SAP have not been read.	Original registration, protocol, SAP, amendments and prespecification records	When original registration and planning materials are provided, link their original form and amendment history separately.
15	Partly verified	Full text not readStored summary read	N15 · Comparative efficacyIs the specific postcard study equivalent to a review of several brief-contact interventions?Required	The Milner 2015 review synthesizes 14 trials of letters, postcards, calls and cards as evidence for the intervention class. R02	Only the relevant information from the stored summary is recorded. Detailed original materials have not been read, and the original content review remains incomplete. Effects of all brief contacts are not equated with this eight-postcard exposure. Populations, exposures and endpoints of individual included trials have not been read.	Review populations, interventions, comparators, eligibility and original-trial mapping	Obtain mappings of included trials, interventions, comparators and populations.
16	Partly verified	Full text not readStored summary read	N16 · Comparative efficacyIs the review OR for any repetition distinguished from the difference in the direct trial?Required	The original text preserves the review OR for any repetition as 0.87 (95% CI 0.74–1.04). R02	Only the relevant information from the stored summary is recorded. Detailed original materials have not been read, and the original content review remains incomplete. The OR is not converted into the direct trial's proportion difference, RR or person counts. The summary does not provide the number of trials for this endpoint, total participants, periods or heterogeneity.	Pooled effects on people with repetition, intervals, trial-specific denominators, periods and models	Obtain endpoint-specific included trials, denominators, periods, models and heterogeneity from the review.
17	Partly verified	Full text not readStored summary read	N17 · Comparative efficacyAre the review results for repeat counts and suicide separated from evidence on the selected people-with-repetition endpoint?Required	The review separately records suicide OR 0.58 (0.24–1.38) and repeat events per person IRR 0.66 (0.54–0.80). R02	Only the relevant information from the stored summary is recorded. Detailed original materials have not been read, and the original content review remains incomplete. Interval levels not separately specified in the original stored summary are not newly added. Suicide and event-count effects are not repurposed as effects on people with repetition.	Separate materials on endpoint-specific effects, interval levels, denominators and definitions	Obtain each endpoint's definition, included trials, denominators, intervals and prespecified plans separately.
18	Partly verified	Full text not readStored summary read	N18 · Comparative efficacyAre the review's 14 trials, the Carter trial and sibling sheets protected against double-counting?Required	The original materials explicitly state that synthesis evidence is not double-counted as replication trials in the review's funding field. Subclaim sheets share the Carter materials and parent summary. R01 R02	Only the relevant information from the stored summary is recorded. Detailed original materials have not been read, and the original content review remains incomplete. The 14 trials are not declared a new independent replication count, and trials or participants are not added together. The overlap list of included trials has not been read.	Relationships among original trials, synthesis reports, shared populations and endpoints	Link original-trial lists, shared participants and report relationships from the review without newly certifying independence.
19	Unverified	Full text not readStored summary read	N19 · Comparative efficacyAre gaps in direct evidence for secondary results, subgroups and repeater analyses retained?Required	The original materials focus on two coprimary results, an explanation about a small group of repeaters and the review. R01	Only the relevant information from the stored summary is recorded. Detailed original materials have not been read, and the original content review remains incomplete. Subgroup effects, denominators and P values absent from the original text, including those for sex, age and prior repetition, are not created. Explanations are not upgraded to proof of prespecified subgroup effects.	Outcome hierarchy, prespecified subgroups, interactions, original effects and denominators	Obtain original secondary-outcome and subgroup plans, interactions, denominators and multiplicity materials.
20	Partly verified	Full text not readStored summary read	N20 · Comparative efficacyAre nonsignificant results and intervals distinguished from clinically important reductions in repetition?Required	The preserved subclaim note states that the repeater CI, −7 to 3 percentage points, includes zero. R01	Only the relevant information from the stored summary is recorded. Detailed original materials have not been read, and the original content review remains incomplete. The summary has no prespecified importance threshold, so exclusion of all meaningful effects, equivalence or universal lack of effect is not newly certified.	Importance thresholds, original between-group effects, intervals and prespecified plans	Link prespecified clinical thresholds and original plans for each endpoint, population and period when provided.
21	Partly verified	Full text not readStored summary read	N21 · Comparative efficacyAre repetition, event counts, suicide deaths and other clinical outcomes kept distinct?Required	The stored summary records that the trial did not demonstrate fewer suicide deaths. R01 R02	Only the relevant information from the stored summary is recorded. Detailed original materials have not been read, and the original content review remains incomplete. Reduced repeat-event counts are not extended to fewer deaths, prevention of all repetition or benefits of other clinical treatments.	Direct distinction among people with repetition, events, deaths and other treatment outcomes	Link direct episode definitions, follow-up, denominators and effects separately for each clinical question.
22	Partly verified	Full text not readStored summary read	N22 · Comparative efficacyHas guidance for widespread implementation or treatment replacement been avoided?Required	The preserved text states that the review concluded widespread clinical implementation could not yet be recommended. R01 R02	Only the relevant information from the stored summary is recorded. Detailed original materials have not been read, and the original content review remains incomplete. This production is not guidance for personal contact, support actions, treatment changes or methods of repeating the behavior. A specific trial is not extended to every support approach.	Application boundaries by population, intervention and comparator, and the original verdict context	When direct materials on target populations and support are provided, link them separately for user review.
23	Partly verified	Full text not readStored summary read	N23 · Comparative efficacyAre public/nonprofit support and gaps in detailed involvement distinguished?Required	The Carter study was supported by Hunter Area Health Service, NSW Health and NHMRC. The review records funding as varying among original trials. R01 R02	Only the relevant information from the stored summary is recorded. Detailed original materials have not been read, and the original content review remains incomplete. Funding labels alone do not establish absence of supplied products/services, employee authors or external analysis roles, and do not newly certify independence.	Cash funding, supplied products/services, affiliated authors and external analysis roles	Obtain original support, affiliation, study-role and analysis disclosures separately for the trial and review.
24	Partly verified	Full text not readStored summary read	N24 · Supplementary harm evidenceAre absence of a separate adverse-event endpoint and unknown safety preserved?Required	The stored summary records that safety was insufficiently assessed without a separate adverse-event endpoint; parent safety is unknown. R01	Only the relevant information from the stored summary is recorded. Detailed original materials have not been read, and the original content review remains incomplete. This is not relabelled as zero adverse events, no serious harm or a safe intervention.	Original harm collection, events by group, exposure, denominators and relatedness data	Obtain original harm collection, events by group, exposure, denominators, relatedness and discontinuation materials.
25	Partly verified	Full text not readStored summary read	N25 · Supplementary harm evidenceAre inconclusive mortality results separated from long-term and rare harms?Required	The trial did not establish reduced suicide mortality; the review records the suicide OR interval as 0.24–1.38. R01 R02	Only the relevant information from the stored summary is recorded. Detailed original materials have not been read, and the original content review remains incomplete. Nonsignificance is not described as absence of mortality risk. Death counts, harm rates and long-term safety absent from the original text are not created.	Deaths, severity, periods, exposure, effect intervals and direct harm data	Obtain endpoint-specific deaths, serious events, observation periods, exposure and direct harm data.
26	Unverified	Full text not readStored summary read	N26 · Supplementary harm evidenceAre gaps in harm replication and application to other populations, interventions and contacts retained?Required	The original study involved a specific population after hospital treatment and a postcard intervention; the review covered various brief contacts. R01 R02	Only the relevant information from the stored summary is recorded. Detailed original materials have not been read, and the original content review remains incomplete. Absence of harm or efficacy across all contacts and other populations is not newly established, and clinical implementation is not directed.	Direct harms by population, exposure and service, and shared-population relationships	Link direct materials by intervention and population, harm follow-up and report relationships separately.
27	Partly verified	Full text not readStored summary read	N27 · Comparative efficacyAre reading of summaries and external abstracts, full texts, registrations, protocols and SAP distinguished?Required	The whole stored parent-verdict summary was read for production, linking the two PubMed URLs and the original ACTRN identifier. R01 R02	Only the relevant information from the stored summary is recorded. Detailed original materials have not been read, and the original content review remains incomplete. Existing links do not indicate completed external acquisition, reading or review. Full texts and plans for the review and original trial have not been read.	Original URLs, stored summaries, identifiers and individual actual-access records	Link user-provided materials to their individual types and access status.
28	Partly verified	Full text not readStored summary read	N28 · Comparative efficacyAre the cut-off, original subclaim/parent values, Korean/English texts, corrections and empty fields preserved?Required	The cut-off 2026-08-26, empty correction and deliberation fields, Korean/English texts, parent C56, unknown safety, true split-coprimary flag and subclaim D are preserved. R01 R02	Only the relevant information from the stored summary is recorded. Detailed original materials have not been read, and the original content review remains incomplete. This production date is not substituted as a new clinical-verification date. Original cross-check wording is historical and does not indicate review completion here.	Whole stored summary, selected verdict record and original verdict history	Link new materials and decisions as separate events while preserving the entire original text.
29	Partly verified	Full text not readStored summary read	N29 · Comparative efficacyAre user-review indicators separated from production and independence status?Supplementary	Original review-pending/production-eligible indicators and boundary-review requirements are preserved as history. The original content review remains incomplete; active-pending and completion flags for model, content and boundary reviews are false. R01 R02	Only the relevant information from the stored summary is recorded. Detailed original materials have not been read, and the original content review remains incomplete. No new verdict, split or independence certification is made; added verdict units are 0 and the final independence count is not recorded.	Original candidate history and current production/review status	Reflect only user-provided decisions and materials as separate events.

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29 itemsWhat the statuses mean

Assessment scope

Stored-material review date: Not recorded
Original evidence cut-off: 2026-08-26
Scope actually checked: Existing review summaries and stored records of methodological application. Full papers, supplements, registrations, plans and original data were not read.
What the dates mean: This is the date the stored materials were checked, not the date of a new search of the clinical literature.
Population: Participants aged 16 or older after hospital treatment in Newcastle, Australia; detailed eligibility and baseline characteristics have not been read
Ingredient, formulation and route: Historical study exposure to eight non-obligatory postcards over 12 months; detailed existing treatment and actual receipt remain unverified
Dose: Only original study exposure is preserved; no mailing schedule, wording, support actions or treatment implementation guidance is generated
Comparator: Usual care in the original trial; detailed existing treatment and concomitant care have not been read
Measured outcome: Selected endpoint: people with any repetition; the coprimary repeat-event count and mortality are separate
Duration: 12 months in the original trial; detailed review periods and follow-up denominators have not been read
Questions outside this scope: Repurposing repeat-event counts as fewer people with repetition; Establishing reductions in repetition or mortality, effects across all contacts, or widespread implementation; Personal support actions or treatment instructions; Descriptions of methods of repeating the behavior

Evidence and sources

The links below lead to the sources. A link alone does not mean the original source was read or its latest publication status verified.

R01 · Carter GL, Clover K, Whyte IM, Dawson AH, D'Este C. Postcards from the EDge project: randomised controlled trial of an intervention using postcards to reduce repetition of hospital treated deliberate self poisoning. BMJ. 2005;331:805. PMID: 16183654.

PubMed

Material type: Trial report
Materials actually read: Summary read; external materials not read
Findings recorded in the stored summary: Repeaters 15.1% vs 17.3%, difference −2 percentage points (−7 to 3); events 101 vs 192, IRR 0.55 (0.35–0.87)
Record level: Stored review summary; not results from directly reading the original paper or review
Study overlap and independent replication: Original Carter trial; the two subquestions concern the same participants. Synthesis report of 14 trials; overlap among included original trials and endpoint-specific denominators have not been read. Family IDs link relationships and do not certify unique-trial counts; reports, time points, reviews, sibling sheets and shared participants are not newly added as independent materials.

Public availability, access and reading status by material
Material	Public availability	Access status	Actually read	Notes
local_summary	Original source link preserved	Summary read	Summary read	Preserved parent verdict summary
abstract	Original source link preserved	Not read	Not read	External material unread; a URL does not mean acquisition, reading or completed review
fulltext	No separate URL in the original material	Not read	Not read	External material unread; a URL does not mean acquisition, reading or completed review
registration	No separate URL in the original material	Not read	Not read	External material unread; a URL does not mean acquisition, reading or completed review
protocol_sap	No separate URL in the original material	Not read	Not read	External material unread; a URL does not mean acquisition, reading or completed review

R02 · Milner AJ, Carter G, Pirkis J, Robinson J, Spittal MJ. Letters, green cards, telephone calls and postcards: systematic and meta-analytic review of brief contact interventions. Br J Psychiatry. 2015;206:184-190. PMID: 25733570.

PubMed

Material type: Systematic review
Materials actually read: Summary read; external materials not read
Findings recorded in the stored summary: OR 0.87(0.74~1.04), OR 0.58(0.24~1.38), IRR 0.66(0.54~0.80)
Record level: Stored review summary; not results from directly reading the original paper or review
Study overlap and independent replication: Original Carter trial; the two subquestions concern the same participants. Synthesis report of 14 trials; overlap among included original trials and endpoint-specific denominators have not been read. Family IDs link relationships and do not certify unique-trial counts; reports, time points, reviews, sibling sheets and shared participants are not newly added as independent materials.

Public availability, access and reading status by material
Material	Public availability	Access status	Actually read	Notes
local_summary	Original source link preserved	Summary read	Summary read	Preserved parent verdict summary
abstract	Original source link preserved	Not read	Not read	External material unread; a URL does not mean acquisition, reading or completed review
fulltext	No separate URL in the original material	Not read	Not read	External material unread; a URL does not mean acquisition, reading or completed review
registration	No separate URL in the original material	Not read	Not read	External material unread; a URL does not mean acquisition, reading or completed review
protocol_sap	No separate URL in the original material	Not read	Not read	External material unread; a URL does not mean acquisition, reading or completed review

Report counts versus independent study counts

Original Carter trial; the two subquestions concern the same participants. Synthesis report of 14 trials; overlap among included original trials and endpoint-specific denominators have not been read. Family IDs link relationships and do not certify unique-trial counts; reports, time points, reviews, sibling sheets and shared participants are not newly added as independent materials.

Review criteria

Version 1.0 · Criteria record date 2026-10-06. These are Chamgap's own application conditions, informed by the referenced methods. They do not constitute official assessment-tool certification or a new efficacy score.

N01 · Are the selected reduction in people with any repetition and the parent repeat-event result distinguished?

Required materials and conditions: Separate records of the original subclaim, grade, note and parent results
Conditions for verification: Separate records of the original subclaim, grade, note and parent results
Requirement and applicability: Required
Application exceptions: Unread external materials, different comparisons or out-of-scope results do not substitute for fulfilled conditions, zero effect or safety.
Why this condition is needed: An individual production condition recording original values, direct comparisons and application boundaries for the selected question
Referenced methods: Fewer people with any repetition

N02 · Who was recruited after hospital treatment and what is the scope of application?

Required materials and conditions: Prior episodes, age, location, eligibility, baseline characteristics and denominators
Conditions for verification: Prior episodes, age, location, eligibility, baseline characteristics and denominators
Requirement and applicability: Required
Application exceptions: Unread external materials, different comparisons or out-of-scope results do not substitute for fulfilled conditions, zero effect or safety.
Why this condition is needed: An individual production condition recording original values, direct comparisons and application boundaries for the selected question
Referenced methods: Fewer people with any repetition

N03 · Are non-obligatory postcard exposure and the existing-treatment comparator distinguished?

Required materials and conditions: Records of historical study exposure, usual care and concomitant care by group
Conditions for verification: Records of historical study exposure, usual care and concomitant care by group
Requirement and applicability: Required
Application exceptions: Unread external materials, different comparisons or out-of-scope results do not substitute for fulfilled conditions, zero effect or safety.
Why this condition is needed: An individual production condition recording original values, direct comparisons and application boundaries for the selected question
Referenced methods: Fewer people with any repetition

N04 · Are the units of randomized people, people with repetition and repeat events preserved separately?

Required materials and conditions: Distinguishing randomized denominators, individual repetition and event counts
Conditions for verification: Distinguishing randomized denominators, individual repetition and event counts
Requirement and applicability: Required
Application exceptions: Unread external materials, different comparisons or out-of-scope results do not substitute for fulfilled conditions, zero effect or safety.
Why this condition is needed: An individual production condition recording original values, direct comparisons and application boundaries for the selected question
Referenced methods: Fewer people with any repetition

N05 · What are the definition, follow-up period and ascertainment scope for people with any repetition?

Required materials and conditions: Episode definition, hospital treatment, follow-up period and administrative-data scope
Conditions for verification: Episode definition, hospital treatment, follow-up period and administrative-data scope
Requirement and applicability: Required
Application exceptions: Unread external materials, different comparisons or out-of-scope results do not substitute for fulfilled conditions, zero effect or safety.
Why this condition is needed: An individual production condition recording original values, direct comparisons and application boundaries for the selected question
Referenced methods: Fewer people with any repetition

N06 · Are 57/378 versus 68/394 and the proportions preserved as originally recorded?

Required materials and conditions: People with repetition by group, original denominators, proportions and analysis populations
Conditions for verification: People with repetition by group, original denominators, proportions and analysis populations
Requirement and applicability: Required
Application exceptions: Unread external materials, different comparisons or out-of-scope results do not substitute for fulfilled conditions, zero effect or safety.
Why this condition is needed: An individual production condition recording original values, direct comparisons and application boundaries for the selected question
Referenced methods: Fewer people with any repetition

N07 · Are the difference in repeater proportions, its interval and the missing P value preserved?

Required materials and conditions: Original between-group difference, interval, test, denominators and model
Conditions for verification: Original between-group difference, interval, test, denominators and model
Requirement and applicability: Required
Application exceptions: Unread external materials, different comparisons or out-of-scope results do not substitute for fulfilled conditions, zero effect or safety.
Why this condition is needed: An individual production condition recording original values, direct comparisons and application boundaries for the selected question
Referenced methods: Fewer people with any repetition

N08 · Do 101 versus 192 repeat events and the IRR describe the selected effect on people with repetition?

Required materials and conditions: Separate records of event counts, person counts, exposure time and incidence rate ratio
Conditions for verification: Separate records of event counts, person counts, exposure time and incidence rate ratio
Requirement and applicability: Required
Application exceptions: Unread external materials, different comparisons or out-of-scope results do not substitute for fulfilled conditions, zero effect or safety.
Why this condition is needed: An individual production condition recording original values, direct comparisons and application boundaries for the selected question
Referenced methods: Fewer people with any repetition

N09 · Are total events, repeat events per person and the contribution of a small group of repeaters distinguished?

Required materials and conditions: Original data on event distributions, individual repetition, observation time and models
Conditions for verification: Original data on event distributions, individual repetition, observation time and models
Requirement and applicability: Required
Application exceptions: Unread external materials, different comparisons or out-of-scope results do not substitute for fulfilled conditions, zero effect or safety.
Why this condition is needed: An individual production condition recording original values, direct comparisons and application boundaries for the selected question
Referenced methods: Fewer people with any repetition

N10 · Are the split coprimary outcomes and selected subclaim grade D displayed together?

Required materials and conditions: Coprimary designation, individual effects, tests and multiplicity plans
Conditions for verification: Coprimary designation, individual effects, tests and multiplicity plans
Requirement and applicability: Required
Application exceptions: Unread external materials, different comparisons or out-of-scope results do not substitute for fulfilled conditions, zero effect or safety.
Why this condition is needed: An individual production condition recording original values, direct comparisons and application boundaries for the selected question
Referenced methods: Fewer people with any repetition

N11 · What is the recorded information on randomization, concealment, blinding and administrative measurement?

Required materials and conditions: Allocation, concealment, participant/outcome measurement and analyst procedures
Conditions for verification: Allocation, concealment, participant/outcome measurement and analyst procedures
Requirement and applicability: Required
Application exceptions: Unread external materials, different comparisons or out-of-scope results do not substitute for fulfilled conditions, zero effect or safety.
Why this condition is needed: An individual production condition recording original values, direct comparisons and application boundaries for the selected question
Referenced methods: Fewer people with any repetition

N12 · Do gaps remain in 12-month follow-up, missing data, deaths, relocation and analysis populations?

Required materials and conditions: Follow-up by group, reasons for missing data, competing events, analysis populations and sensitivity analyses
Conditions for verification: Follow-up by group, reasons for missing data, competing events, analysis populations and sensitivity analyses
Requirement and applicability: Required
Application exceptions: Unread external materials, different comparisons or out-of-scope results do not substitute for fulfilled conditions, zero effect or safety.
Why this condition is needed: An individual production condition recording original values, direct comparisons and application boundaries for the selected question
Referenced methods: Fewer people with any repetition

N13 · Can actual postcard receipt, replies, existing treatment exposure and adherence be verified?

Required materials and conditions: Actual study exposure, receipt, discontinuation, treatment use and concomitant treatment records
Conditions for verification: Actual study exposure, receipt, discontinuation, treatment use and concomitant treatment records
Requirement and applicability: Required
Application exceptions: Unread external materials, different comparisons or out-of-scope results do not substitute for fulfilled conditions, zero effect or safety.
Why this condition is needed: An individual production condition recording original values, direct comparisons and application boundaries for the selected question
Referenced methods: Fewer people with any repetition

N14 · Are prespecified plans and the registration identifier distinguished from actual reading of the registration?

Required materials and conditions: Original registration, protocol, SAP, amendments and prespecification records
Conditions for verification: Original registration, protocol, SAP, amendments and prespecification records
Requirement and applicability: Required
Application exceptions: Unread external materials, different comparisons or out-of-scope results do not substitute for fulfilled conditions, zero effect or safety.
Why this condition is needed: An individual production condition recording original values, direct comparisons and application boundaries for the selected question
Referenced methods: Fewer people with any repetition

N15 · Is the specific postcard study equivalent to a review of several brief-contact interventions?

Required materials and conditions: Review populations, interventions, comparators, eligibility and original-trial mapping
Conditions for verification: Review populations, interventions, comparators, eligibility and original-trial mapping
Requirement and applicability: Required
Application exceptions: Unread external materials, different comparisons or out-of-scope results do not substitute for fulfilled conditions, zero effect or safety.
Why this condition is needed: An individual production condition recording original values, direct comparisons and application boundaries for the selected question
Referenced methods: Fewer people with any repetition

N16 · Is the review OR for any repetition distinguished from the difference in the direct trial?

Required materials and conditions: Pooled effects on people with repetition, intervals, trial-specific denominators, periods and models
Conditions for verification: Pooled effects on people with repetition, intervals, trial-specific denominators, periods and models
Requirement and applicability: Required
Application exceptions: Unread external materials, different comparisons or out-of-scope results do not substitute for fulfilled conditions, zero effect or safety.
Why this condition is needed: An individual production condition recording original values, direct comparisons and application boundaries for the selected question
Referenced methods: Fewer people with any repetition

N17 · Are the review results for repeat counts and suicide separated from evidence on the selected people-with-repetition endpoint?

Required materials and conditions: Separate materials on endpoint-specific effects, interval levels, denominators and definitions
Conditions for verification: Separate materials on endpoint-specific effects, interval levels, denominators and definitions
Requirement and applicability: Required
Application exceptions: Unread external materials, different comparisons or out-of-scope results do not substitute for fulfilled conditions, zero effect or safety.
Why this condition is needed: An individual production condition recording original values, direct comparisons and application boundaries for the selected question
Referenced methods: Fewer people with any repetition

N18 · Are the review's 14 trials, the Carter trial and sibling sheets protected against double-counting?

Required materials and conditions: Relationships among original trials, synthesis reports, shared populations and endpoints
Conditions for verification: Relationships among original trials, synthesis reports, shared populations and endpoints
Requirement and applicability: Required
Application exceptions: Unread external materials, different comparisons or out-of-scope results do not substitute for fulfilled conditions, zero effect or safety.
Why this condition is needed: An individual production condition recording original values, direct comparisons and application boundaries for the selected question
Referenced methods: Fewer people with any repetition

N19 · Are gaps in direct evidence for secondary results, subgroups and repeater analyses retained?

Required materials and conditions: Outcome hierarchy, prespecified subgroups, interactions, original effects and denominators
Conditions for verification: Outcome hierarchy, prespecified subgroups, interactions, original effects and denominators
Requirement and applicability: Required
Application exceptions: Unread external materials, different comparisons or out-of-scope results do not substitute for fulfilled conditions, zero effect or safety.
Why this condition is needed: An individual production condition recording original values, direct comparisons and application boundaries for the selected question
Referenced methods: Fewer people with any repetition

N20 · Are nonsignificant results and intervals distinguished from clinically important reductions in repetition?

Required materials and conditions: Importance thresholds, original between-group effects, intervals and prespecified plans
Conditions for verification: Importance thresholds, original between-group effects, intervals and prespecified plans
Requirement and applicability: Required
Application exceptions: Unread external materials, different comparisons or out-of-scope results do not substitute for fulfilled conditions, zero effect or safety.
Why this condition is needed: An individual production condition recording original values, direct comparisons and application boundaries for the selected question
Referenced methods: Fewer people with any repetition

N21 · Are repetition, event counts, suicide deaths and other clinical outcomes kept distinct?

Required materials and conditions: Direct distinction among people with repetition, events, deaths and other treatment outcomes
Conditions for verification: Direct distinction among people with repetition, events, deaths and other treatment outcomes
Requirement and applicability: Required
Application exceptions: Unread external materials, different comparisons or out-of-scope results do not substitute for fulfilled conditions, zero effect or safety.
Why this condition is needed: An individual production condition recording original values, direct comparisons and application boundaries for the selected question
Referenced methods: Fewer people with any repetition

N22 · Has guidance for widespread implementation or treatment replacement been avoided?

Required materials and conditions: Application boundaries by population, intervention and comparator, and the original verdict context
Conditions for verification: Application boundaries by population, intervention and comparator, and the original verdict context
Requirement and applicability: Required
Application exceptions: Unread external materials, different comparisons or out-of-scope results do not substitute for fulfilled conditions, zero effect or safety.
Why this condition is needed: An individual production condition recording original values, direct comparisons and application boundaries for the selected question
Referenced methods: Fewer people with any repetition

N23 · Are public/nonprofit support and gaps in detailed involvement distinguished?

Required materials and conditions: Cash funding, supplied products/services, affiliated authors and external analysis roles
Conditions for verification: Cash funding, supplied products/services, affiliated authors and external analysis roles
Requirement and applicability: Required
Application exceptions: Unread external materials, different comparisons or out-of-scope results do not substitute for fulfilled conditions, zero effect or safety.
Why this condition is needed: An individual production condition recording original values, direct comparisons and application boundaries for the selected question
Referenced methods: Fewer people with any repetition

N24 · Are absence of a separate adverse-event endpoint and unknown safety preserved?

Required materials and conditions: Original harm collection, events by group, exposure, denominators and relatedness data
Conditions for verification: Original harm collection, events by group, exposure, denominators and relatedness data
Requirement and applicability: Required
Application exceptions: Unread external materials, different comparisons or out-of-scope results do not substitute for fulfilled conditions, zero effect or safety.
Why this condition is needed: An individual production condition recording original values, direct comparisons and application boundaries for the selected question
Referenced methods: Fewer people with any repetition

N25 · Are inconclusive mortality results separated from long-term and rare harms?

Required materials and conditions: Deaths, severity, periods, exposure, effect intervals and direct harm data
Conditions for verification: Deaths, severity, periods, exposure, effect intervals and direct harm data
Requirement and applicability: Required
Application exceptions: Unread external materials, different comparisons or out-of-scope results do not substitute for fulfilled conditions, zero effect or safety.
Why this condition is needed: An individual production condition recording original values, direct comparisons and application boundaries for the selected question
Referenced methods: Fewer people with any repetition

N26 · Are gaps in harm replication and application to other populations, interventions and contacts retained?

Required materials and conditions: Direct harms by population, exposure and service, and shared-population relationships
Conditions for verification: Direct harms by population, exposure and service, and shared-population relationships
Requirement and applicability: Required
Application exceptions: Unread external materials, different comparisons or out-of-scope results do not substitute for fulfilled conditions, zero effect or safety.
Why this condition is needed: An individual production condition recording original values, direct comparisons and application boundaries for the selected question
Referenced methods: Fewer people with any repetition

N27 · Are reading of summaries and external abstracts, full texts, registrations, protocols and SAP distinguished?

Required materials and conditions: Original URLs, stored summaries, identifiers and individual actual-access records
Conditions for verification: Original URLs, stored summaries, identifiers and individual actual-access records
Requirement and applicability: Required
Application exceptions: Unread external materials, different comparisons or out-of-scope results do not substitute for fulfilled conditions, zero effect or safety.
Why this condition is needed: An individual production condition recording original values, direct comparisons and application boundaries for the selected question
Referenced methods: Fewer people with any repetition

N28 · Are the cut-off, original subclaim/parent values, Korean/English texts, corrections and empty fields preserved?

Required materials and conditions: Whole stored summary, selected verdict record and original verdict history
Conditions for verification: Whole stored summary, selected verdict record and original verdict history
Requirement and applicability: Required
Application exceptions: Unread external materials, different comparisons or out-of-scope results do not substitute for fulfilled conditions, zero effect or safety.
Why this condition is needed: An individual production condition recording original values, direct comparisons and application boundaries for the selected question
Referenced methods: Fewer people with any repetition

N29 · Are user-review indicators separated from production and independence status?

Required materials and conditions: Original candidate history and current production/review status
Conditions for verification: Original candidate history and current production/review status
Requirement and applicability: Supplementary
Application exceptions: Unread external materials, different comparisons or out-of-scope results do not substitute for fulfilled conditions, zero effect or safety.
Why this condition is needed: An individual production condition recording original values, direct comparisons and application boundaries for the selected question
Referenced methods: Fewer people with any repetition

Referenced methods and the sections actually reviewed

M03 · Cochrane Handbook 6.5 (2024), chapter updated 2023-08

Official methodology · §3.1, §3.2.1–3.2.3, MECIR C5/C7/C13

Referenced principle: Clearly record the question, eligibility conditions and reasons for changes, and distinguish variations in interventions.
Extent of review: Preserved methodology connections were reused for preparation. No new review of methodological content, reassessment or external-link checks were performed.

M04 · Cochrane Handbook 6.5.1 (2025), chapter updated 2025-03

Official methodology · §4.5, §4.6.1–4.6.3, MECIR C42

Referenced principle: Distinguish studies from reports and link them; do not omit a study solely because results are unreported.
Extent of review: Preserved methodology connections were reused for preparation. No new review of methodological content, reassessment or external-link checks were performed.

M08 · Cochrane Handbook 6.5 (2024), chapter updated 2019-10

Official methodology · §8.1–8.2.3, Table 8.2.a

Referenced principle: Define the outcome and effect of interest, then examine randomization, deviations, missing data, measurement and selective reporting.
Extent of review: Preserved methodology connections were reused for preparation. No new review of methodological content, reassessment or external-link checks were performed.

M15 · Cochrane Handbook 6.5 (2024), chapter updated 2023-08

Official methodology · §15.2.4, §15.3.1–15.3.3

Referenced principle: Distinguish effect estimates, intervals, importance and applicability. Sample size alone does not determine precision.
Extent of review: Preserved methodology connections were reused for preparation. No new review of methodological content, reassessment or external-link checks were performed.

M19 · Cochrane Handbook 6.5 (2024), chapter updated 2019-10

Official methodology · §19.1.2, §19.2.1–19.2.4

Referenced principle: Harm questions may require different designs, populations and follow-up from efficacy questions. Case reports do not establish incidence rates.
Extent of review: Preserved methodology connections were reused for preparation. No new review of methodological content, reassessment or external-link checks were performed.

What the statuses mean

Partly verified: Some information exists in the preserved review summary; detailed original materials remain unverified. This does not certify a passed review or clinical efficacy.
Unverified: Detailed materials for the selected condition could not be established within the stored scope; this does not mean zero effect, zero studies or safety
Review incomplete: Review of existing content incomplete
Met: Use only within the relevant conditions after existing content review; no automatic designation in this preparation
Not reported: Distinguish only within materials actually read; do not turn unread external materials into unreported findings
Inaccessible: Not applied during this preparation because actual access was not tested
Not applicable: Use with a reason for non-applicability based on an explicit question boundary
Conflicting data: Judge after actual material comparison; review was not performed during this preparation
Insufficient evidence for the conditions: Do not use as a clinical grade encompassing currently unread materials

Change history

2026-10-11 · Public page/material version 1.0

Public pages and materials were created from the existing 29 items. No new clinical search, verification-status change or scoring was performed.

The stored-material review date (Not recorded) and original evidence cut-off (2026-08-26) were retained unchanged.

Researcher downloads

These materials provide the same evidence, scope and verification status as this page.

View all item details

N01 · Are the selected reduction in people with any repetition and the parent repeat-event result distinguished?

Current findings: The selected original question is ‘Fewer people with any repetition’, with original grade D and a note describing 15.1% versus 17.3% and a CI including zero. The parent verdict concerns fewer repeat events, grade C, 56 points and unknown safety.
Verification status: Partly verified
Materials actually read: Summary read; external materials not read
Why unverified: Only the relevant information from the stored summary is recorded. Detailed original materials have not been read, and the original content review remains incomplete. Missing subclaim score, status and axes are not filled with the parent score. No new verdict is made.
Reason for missing information: Missing subclaim score, status and axes are not filled with the parent score. No new verdict is made.
Required materials and conditions: Separate records of the original subclaim, grade, note and parent results
Materials to obtain first: Missing subclaim score, status and axes are not filled with the parent score. No new verdict is made.
Further research: Additional materials are linked separately to the selected any-repetition endpoint and the repeat-event endpoint.
Remaining uncertainty: Unread or unverified materials do not mean zero effect, zero events, safety or new clinical certification.
Conditions for verification: Separate records of the original subclaim, grade, note and parent results
Why this condition is needed: An individual production condition recording original values, direct comparisons and application boundaries for the selected question
Application exceptions: Unread external materials, different comparisons or out-of-scope results do not substitute for fulfilled conditions, zero effect or safety.
Referenced methods: Fewer people with any repetition

Related sources R01

N02 · Who was recruited after hospital treatment and what is the scope of application?

Current findings: The recorded study population comprises 772 participants aged 16 or older after hospital treatment in Newcastle, Australia.
Verification status: Partly verified
Materials actually read: Summary read; external materials not read
Why unverified: Only the relevant information from the stored summary is recorded. Detailed original materials have not been read, and the original content review remains incomplete. The results are not automatically applied to other locations, ages, prior treatments or episode types. Detailed eligibility, baseline characteristics and histories of previous repetition have not been read.
Reason for missing information: The results are not automatically applied to other locations, ages, prior treatments or episode types. Detailed eligibility, baseline characteristics and histories of previous repetition have not been read.
Required materials and conditions: Prior episodes, age, location, eligibility, baseline characteristics and denominators
Materials to obtain first: The results are not automatically applied to other locations, ages, prior treatments or episode types. Detailed eligibility, baseline characteristics and histories of previous repetition have not been read.
Further research: Obtain original eligibility, baseline characteristics, individual histories of repetition and treatment records.
Remaining uncertainty: Unread or unverified materials do not mean zero effect, zero events, safety or new clinical certification.
Conditions for verification: Prior episodes, age, location, eligibility, baseline characteristics and denominators
Why this condition is needed: An individual production condition recording original values, direct comparisons and application boundaries for the selected question
Application exceptions: Unread external materials, different comparisons or out-of-scope results do not substitute for fulfilled conditions, zero effect or safety.
Referenced methods: Fewer people with any repetition

Related sources R01

N03 · Are non-obligatory postcard exposure and the existing-treatment comparator distinguished?

Current findings: The original intervention consisted of 8 postcards requiring no reply over 12 months; the comparator was usual care.
Verification status: Partly verified
Materials actually read: Summary read; external materials not read
Why unverified: Only the relevant information from the stored summary is recorded. Detailed original materials have not been read, and the original content review remains incomplete. Detailed mailing times, wording, actual receipt, existing treatment and additional care have not been read. No personal support actions, treatment or implementation instructions are created.
Reason for missing information: Detailed mailing times, wording, actual receipt, existing treatment and additional care have not been read. No personal support actions, treatment or implementation instructions are created.
Required materials and conditions: Records of historical study exposure, usual care and concomitant care by group
Materials to obtain first: Detailed mailing times, wording, actual receipt, existing treatment and additional care have not been read. No personal support actions, treatment or implementation instructions are created.
Further research: Obtain original intervention, actual exposure, usual-care and concomitant-care materials.
Remaining uncertainty: Unread or unverified materials do not mean zero effect, zero events, safety or new clinical certification.
Conditions for verification: Records of historical study exposure, usual care and concomitant care by group
Why this condition is needed: An individual production condition recording original values, direct comparisons and application boundaries for the selected question
Application exceptions: Unread external materials, different comparisons or out-of-scope results do not substitute for fulfilled conditions, zero effect or safety.
Referenced methods: Fewer people with any repetition

Related sources R01

N04 · Are the units of randomized people, people with repetition and repeat events preserved separately?

Current findings: Among 772 participants, 378 were assigned to postcards and 394 to usual care. People with any repetition and total events are different units.
Verification status: Partly verified
Materials actually read: Summary read; external materials not read
Why unverified: Only the relevant information from the stored summary is recorded. Detailed original materials have not been read, and the original content review remains incomplete. Events are not converted into people, and people with repetition are not added as new participants. The same participants in sibling sheets are not added together.
Reason for missing information: Events are not converted into people, and people with repetition are not added as new participants. The same participants in sibling sheets are not added together.
Required materials and conditions: Distinguishing randomized denominators, individual repetition and event counts
Materials to obtain first: Events are not converted into people, and people with repetition are not added as new participants. The same participants in sibling sheets are not added together.
Further research: Obtain original mappings of person-level and event-level analyses and follow-up denominators.
Remaining uncertainty: Unread or unverified materials do not mean zero effect, zero events, safety or new clinical certification.
Conditions for verification: Distinguishing randomized denominators, individual repetition and event counts
Why this condition is needed: An individual production condition recording original values, direct comparisons and application boundaries for the selected question
Application exceptions: Unread external materials, different comparisons or out-of-scope results do not substitute for fulfilled conditions, zero effect or safety.
Referenced methods: Fewer people with any repetition

Related sources R01

N05 · What are the definition, follow-up period and ascertainment scope for people with any repetition?

Current findings: The preserved record states that the trial counted hospital-treated episodes through an administrative database over 12 months.
Verification status: Partly verified
Materials actually read: Summary read; external materials not read
Why unverified: Only the relevant information from the stored summary is recorded. Detailed original materials have not been read, and the original content review remains incomplete. Episodes outside hospital, episodes at other institutions, self-reports and deaths are not assigned the same repetition definition. Detailed capture scope and linkage omissions have not been read.
Reason for missing information: Episodes outside hospital, episodes at other institutions, self-reports and deaths are not assigned the same repetition definition. Detailed capture scope and linkage omissions have not been read.
Required materials and conditions: Episode definition, hospital treatment, follow-up period and administrative-data scope
Materials to obtain first: Episodes outside hospital, episodes at other institutions, self-reports and deaths are not assigned the same repetition definition. Detailed capture scope and linkage omissions have not been read.
Further research: Obtain original episode definitions, database, linkage, observation-period and missing-data materials.
Remaining uncertainty: Unread or unverified materials do not mean zero effect, zero events, safety or new clinical certification.
Conditions for verification: Episode definition, hospital treatment, follow-up period and administrative-data scope
Why this condition is needed: An individual production condition recording original values, direct comparisons and application boundaries for the selected question
Application exceptions: Unread external materials, different comparisons or out-of-scope results do not substitute for fulfilled conditions, zero effect or safety.
Referenced methods: Fewer people with any repetition

Related sources R01

N06 · Are 57/378 versus 68/394 and the proportions preserved as originally recorded?

Current findings: People with any repetition numbered 57/378 (15.1%) in the postcard group versus 68/394 (17.3%) with usual care.
Verification status: Partly verified
Materials actually read: Summary read; external materials not read
Why unverified: Only the relevant information from the stored summary is recorded. Detailed original materials have not been read, and the original content review remains incomplete. Proportions are not recalculated, and new person counts, missing denominators or repetition rates are not created.
Reason for missing information: Proportions are not recalculated, and new person counts, missing denominators or repetition rates are not created.
Required materials and conditions: People with repetition by group, original denominators, proportions and analysis populations
Materials to obtain first: Proportions are not recalculated, and new person counts, missing denominators or repetition rates are not created.
Further research: Obtain original person-level episode tables, group denominators, follow-up completeness and analysis populations.
Remaining uncertainty: Unread or unverified materials do not mean zero effect, zero events, safety or new clinical certification.
Conditions for verification: People with repetition by group, original denominators, proportions and analysis populations
Why this condition is needed: An individual production condition recording original values, direct comparisons and application boundaries for the selected question
Application exceptions: Unread external materials, different comparisons or out-of-scope results do not substitute for fulfilled conditions, zero effect or safety.
Referenced methods: Fewer people with any repetition

Related sources R01

N07 · Are the difference in repeater proportions, its interval and the missing P value preserved?

Current findings: The stored summary records a difference of −2 percentage points (95% CI −7 to 3) and judges the repeater result null.
Verification status: Partly verified
Materials actually read: Summary read; external materials not read
Why unverified: Only the relevant information from the stored summary is recorded. Detailed original materials have not been read, and the original content review remains incomplete. P values, RR, OR, NNT or new risk differences absent from the original record are not calculated. An interval including zero does not certify every effect as zero or establish equivalence.
Reason for missing information: P values, RR, OR, NNT or new risk differences absent from the original record are not calculated. An interval including zero does not certify every effect as zero or establish equivalence.
Required materials and conditions: Original between-group difference, interval, test, denominators and model
Materials to obtain first: P values, RR, OR, NNT or new risk differences absent from the original record are not calculated. An interval including zero does not certify every effect as zero or establish equivalence.
Further research: Link original tests, models, intervals, prespecified importance thresholds and denominator materials.
Remaining uncertainty: Unread or unverified materials do not mean zero effect, zero events, safety or new clinical certification.
Conditions for verification: Original between-group difference, interval, test, denominators and model
Why this condition is needed: An individual production condition recording original values, direct comparisons and application boundaries for the selected question
Application exceptions: Unread external materials, different comparisons or out-of-scope results do not substitute for fulfilled conditions, zero effect or safety.
Referenced methods: Fewer people with any repetition

Related sources R01

N08 · Do 101 versus 192 repeat events and the IRR describe the selected effect on people with repetition?

Current findings: Total repeat events fell to 101 versus 192, IRR 0.55 (95% CI 0.35–0.87).
Verification status: Partly verified
Materials actually read: Summary read; external materials not read
Why unverified: Only the relevant information from the stored summary is recorded. Detailed original materials have not been read, and the original content review remains incomplete. Fewer events are not repurposed as fewer people with repetition or confirmed prevention. Person-level distributions, exposure time and models have not been read.
Reason for missing information: Fewer events are not repurposed as fewer people with repetition or confirmed prevention. Person-level distributions, exposure time and models have not been read.
Required materials and conditions: Separate records of event counts, person counts, exposure time and incidence rate ratio
Materials to obtain first: Fewer events are not repurposed as fewer people with repetition or confirmed prevention. Person-level distributions, exposure time and models have not been read.
Further research: Obtain individual repetition distributions, original event tables, exposure and incidence-rate analysis plans.
Remaining uncertainty: Unread or unverified materials do not mean zero effect, zero events, safety or new clinical certification.
Conditions for verification: Separate records of event counts, person counts, exposure time and incidence rate ratio
Why this condition is needed: An individual production condition recording original values, direct comparisons and application boundaries for the selected question
Application exceptions: Unread external materials, different comparisons or out-of-scope results do not substitute for fulfilled conditions, zero effect or safety.
Referenced methods: Fewer people with any repetition

Related sources R01

N09 · Are total events, repeat events per person and the contribution of a small group of repeaters distinguished?

Current findings: The original text explains that only repeated episodes among a small group declined; the recorded endpoints include repeat events per person.
Verification status: Partly verified
Materials actually read: Summary read; external materials not read
Why unverified: Only the relevant information from the stored summary is recorded. Detailed original materials have not been read, and the original content review remains incomplete. Mean event counts, high-frequency subgroup sizes, distributions and sample-specific effects are not newly calculated. The original explanation is not relabelled as a completed subgroup test.
Reason for missing information: Mean event counts, high-frequency subgroup sizes, distributions and sample-specific effects are not newly calculated. The original explanation is not relabelled as a completed subgroup test.
Required materials and conditions: Original data on event distributions, individual repetition, observation time and models
Materials to obtain first: Mean event counts, high-frequency subgroup sizes, distributions and sample-specific effects are not newly calculated. The original explanation is not relabelled as a completed subgroup test.
Further research: Obtain original person-level distributions, repeated-event models, subgroup plans and denominators.
Remaining uncertainty: Unread or unverified materials do not mean zero effect, zero events, safety or new clinical certification.
Conditions for verification: Original data on event distributions, individual repetition, observation time and models
Why this condition is needed: An individual production condition recording original values, direct comparisons and application boundaries for the selected question
Application exceptions: Unread external materials, different comparisons or out-of-scope results do not substitute for fulfilled conditions, zero effect or safety.
Referenced methods: Fewer people with any repetition

Related sources R01

N10 · Are the split coprimary outcomes and selected subclaim grade D displayed together?

Current findings: The original materials record repeater proportion and repeat-event count as coprimary outcomes, with only one succeeding. The original axis flag for split coprimary outcomes is preserved as true.
Verification status: Partly verified
Materials actually read: Summary read; external materials not read
Why unverified: Only the relevant information from the stored summary is recorded. Detailed original materials have not been read, and the original content review remains incomplete. Success on event count is not retained while failure on repeater proportion is omitted, and parent grade C is not transferred to the selected endpoint. Detailed testing and adjustment plans have not been read.
Reason for missing information: Success on event count is not retained while failure on repeater proportion is omitted, and parent grade C is not transferred to the selected endpoint. Detailed testing and adjustment plans have not been read.
Required materials and conditions: Coprimary designation, individual effects, tests and multiplicity plans
Materials to obtain first: Success on event count is not retained while failure on repeater proportion is omitted, and parent grade C is not transferred to the selected endpoint. Detailed testing and adjustment plans have not been read.
Further research: Obtain original protocols, SAP, coprimary endpoint hierarchy, multiplicity plans and individual original tables.
Remaining uncertainty: Unread or unverified materials do not mean zero effect, zero events, safety or new clinical certification.
Conditions for verification: Coprimary designation, individual effects, tests and multiplicity plans
Why this condition is needed: An individual production condition recording original values, direct comparisons and application boundaries for the selected question
Application exceptions: Unread external materials, different comparisons or out-of-scope results do not substitute for fulfilled conditions, zero effect or safety.
Referenced methods: Fewer people with any repetition

Related sources R01

N11 · What is the recorded information on randomization, concealment, blinding and administrative measurement?

Current findings: The stored summary describes a randomized usual-care-controlled trial with unavoidable participant unblinding, while hospital administrative data were used to count episodes.
Verification status: Partly verified
Materials actually read: Summary read; external materials not read
Why unverified: Only the relevant information from the stored summary is recorded. Detailed original materials have not been read, and the original content review remains incomplete. Using administrative data does not certify that all measurement, capture or selection bias was resolved. Allocation-concealment and analyst procedures have not been read.
Reason for missing information: Using administrative data does not certify that all measurement, capture or selection bias was resolved. Allocation-concealment and analyst procedures have not been read.
Required materials and conditions: Allocation, concealment, participant/outcome measurement and analyst procedures
Materials to obtain first: Using administrative data does not certify that all measurement, capture or selection bias was resolved. Allocation-concealment and analyst procedures have not been read.
Further research: Obtain original methods, administrative linkage, allocation, concealment, measurement and analysis procedures.
Remaining uncertainty: Unread or unverified materials do not mean zero effect, zero events, safety or new clinical certification.
Conditions for verification: Allocation, concealment, participant/outcome measurement and analyst procedures
Why this condition is needed: An individual production condition recording original values, direct comparisons and application boundaries for the selected question
Application exceptions: Unread external materials, different comparisons or out-of-scope results do not substitute for fulfilled conditions, zero effect or safety.
Referenced methods: Fewer people with any repetition

Related sources R01

N12 · Do gaps remain in 12-month follow-up, missing data, deaths, relocation and analysis populations?

Current findings: Randomized denominators, the 12-month period and administrative counting are preserved.
Verification status: Unverified
Materials actually read: Summary read; external materials not read
Why unverified: Only the relevant information from the stored summary is recorded. Detailed original materials have not been read, and the original content review remains incomplete. Reporting denominators does not establish complete follow-up for everyone. Detailed handling of withdrawals, relocation and deaths, and ITT procedures, have not been read.
Reason for missing information: Reporting denominators does not establish complete follow-up for everyone. Detailed handling of withdrawals, relocation and deaths, and ITT procedures, have not been read.
Required materials and conditions: Follow-up by group, reasons for missing data, competing events, analysis populations and sensitivity analyses
Materials to obtain first: Reporting denominators does not establish complete follow-up for everyone. Detailed handling of withdrawals, relocation and deaths, and ITT procedures, have not been read.
Further research: Obtain original follow-up flows, administrative capture, analysis populations and missing-data/competing-event plans.
Remaining uncertainty: Unread or unverified materials do not mean zero effect, zero events, safety or new clinical certification.
Conditions for verification: Follow-up by group, reasons for missing data, competing events, analysis populations and sensitivity analyses
Why this condition is needed: An individual production condition recording original values, direct comparisons and application boundaries for the selected question
Application exceptions: Unread external materials, different comparisons or out-of-scope results do not substitute for fulfilled conditions, zero effect or safety.
Referenced methods: Fewer people with any repetition

Related sources R01

N13 · Can actual postcard receipt, replies, existing treatment exposure and adherence be verified?

Current findings: Historical exposure to postcards requiring no reply and the usual-care comparator are recorded.
Verification status: Unverified
Materials actually read: Summary read; external materials not read
Why unverified: Only the relevant information from the stored summary is recorded. Detailed original materials have not been read, and the original content review remains incomplete. Not requiring replies does not mean receipt, contact or treatment use was equal. Numbers received, discontinuation, treatment changes and effect mappings have not been read.
Reason for missing information: Not requiring replies does not mean receipt, contact or treatment use was equal. Numbers received, discontinuation, treatment changes and effect mappings have not been read.
Required materials and conditions: Actual study exposure, receipt, discontinuation, treatment use and concomitant treatment records
Materials to obtain first: Not requiring replies does not mean receipt, contact or treatment use was equal. Numbers received, discontinuation, treatment changes and effect mappings have not been read.
Further research: Obtain actual exposure, receipt, existing treatment, discontinuation and prespecified effects of interest.
Remaining uncertainty: Unread or unverified materials do not mean zero effect, zero events, safety or new clinical certification.
Conditions for verification: Actual study exposure, receipt, discontinuation, treatment use and concomitant treatment records
Why this condition is needed: An individual production condition recording original values, direct comparisons and application boundaries for the selected question
Application exceptions: Unread external materials, different comparisons or out-of-scope results do not substitute for fulfilled conditions, zero effect or safety.
Referenced methods: Fewer people with any repetition

Related sources R01

N14 · Are prespecified plans and the registration identifier distinguished from actual reading of the registration?

Current findings: The original recorded registration string is ACTRN012605000050651. Coprimary designation is preserved in the parent text.
Verification status: Partly verified
Materials actually read: Summary read; external materials not read
Why unverified: Only the relevant information from the stored summary is recorded. Detailed original materials have not been read, and the original content review remains incomplete. The identifier is not arbitrarily corrected and no new URL is constructed. External registration, protocol and SAP have not been read.
Reason for missing information: The identifier is not arbitrarily corrected and no new URL is constructed. External registration, protocol and SAP have not been read.
Required materials and conditions: Original registration, protocol, SAP, amendments and prespecification records
Materials to obtain first: The identifier is not arbitrarily corrected and no new URL is constructed. External registration, protocol and SAP have not been read.
Further research: When original registration and planning materials are provided, link their original form and amendment history separately.
Remaining uncertainty: Unread or unverified materials do not mean zero effect, zero events, safety or new clinical certification.
Conditions for verification: Original registration, protocol, SAP, amendments and prespecification records
Why this condition is needed: An individual production condition recording original values, direct comparisons and application boundaries for the selected question
Application exceptions: Unread external materials, different comparisons or out-of-scope results do not substitute for fulfilled conditions, zero effect or safety.
Referenced methods: Fewer people with any repetition

Related sources R01

N15 · Is the specific postcard study equivalent to a review of several brief-contact interventions?

Current findings: The Milner 2015 review synthesizes 14 trials of letters, postcards, calls and cards as evidence for the intervention class.
Verification status: Partly verified
Materials actually read: Summary read; external materials not read
Why unverified: Only the relevant information from the stored summary is recorded. Detailed original materials have not been read, and the original content review remains incomplete. Effects of all brief contacts are not equated with this eight-postcard exposure. Populations, exposures and endpoints of individual included trials have not been read.
Reason for missing information: Effects of all brief contacts are not equated with this eight-postcard exposure. Populations, exposures and endpoints of individual included trials have not been read.
Required materials and conditions: Review populations, interventions, comparators, eligibility and original-trial mapping
Materials to obtain first: Effects of all brief contacts are not equated with this eight-postcard exposure. Populations, exposures and endpoints of individual included trials have not been read.
Further research: Obtain mappings of included trials, interventions, comparators and populations.
Remaining uncertainty: Unread or unverified materials do not mean zero effect, zero events, safety or new clinical certification.
Conditions for verification: Review populations, interventions, comparators, eligibility and original-trial mapping
Why this condition is needed: An individual production condition recording original values, direct comparisons and application boundaries for the selected question
Application exceptions: Unread external materials, different comparisons or out-of-scope results do not substitute for fulfilled conditions, zero effect or safety.
Referenced methods: Fewer people with any repetition

Related sources R02

N16 · Is the review OR for any repetition distinguished from the difference in the direct trial?

Current findings: The original text preserves the review OR for any repetition as 0.87 (95% CI 0.74–1.04).
Verification status: Partly verified
Materials actually read: Summary read; external materials not read
Why unverified: Only the relevant information from the stored summary is recorded. Detailed original materials have not been read, and the original content review remains incomplete. The OR is not converted into the direct trial's proportion difference, RR or person counts. The summary does not provide the number of trials for this endpoint, total participants, periods or heterogeneity.
Reason for missing information: The OR is not converted into the direct trial's proportion difference, RR or person counts. The summary does not provide the number of trials for this endpoint, total participants, periods or heterogeneity.
Required materials and conditions: Pooled effects on people with repetition, intervals, trial-specific denominators, periods and models
Materials to obtain first: The OR is not converted into the direct trial's proportion difference, RR or person counts. The summary does not provide the number of trials for this endpoint, total participants, periods or heterogeneity.
Further research: Obtain endpoint-specific included trials, denominators, periods, models and heterogeneity from the review.
Remaining uncertainty: Unread or unverified materials do not mean zero effect, zero events, safety or new clinical certification.
Conditions for verification: Pooled effects on people with repetition, intervals, trial-specific denominators, periods and models
Why this condition is needed: An individual production condition recording original values, direct comparisons and application boundaries for the selected question
Application exceptions: Unread external materials, different comparisons or out-of-scope results do not substitute for fulfilled conditions, zero effect or safety.
Referenced methods: Fewer people with any repetition

Related sources R02

N17 · Are the review results for repeat counts and suicide separated from evidence on the selected people-with-repetition endpoint?

Current findings: The review separately records suicide OR 0.58 (0.24–1.38) and repeat events per person IRR 0.66 (0.54–0.80).
Verification status: Partly verified
Materials actually read: Summary read; external materials not read
Why unverified: Only the relevant information from the stored summary is recorded. Detailed original materials have not been read, and the original content review remains incomplete. Interval levels not separately specified in the original stored summary are not newly added. Suicide and event-count effects are not repurposed as effects on people with repetition.
Reason for missing information: Interval levels not separately specified in the original stored summary are not newly added. Suicide and event-count effects are not repurposed as effects on people with repetition.
Required materials and conditions: Separate materials on endpoint-specific effects, interval levels, denominators and definitions
Materials to obtain first: Interval levels not separately specified in the original stored summary are not newly added. Suicide and event-count effects are not repurposed as effects on people with repetition.
Further research: Obtain each endpoint's definition, included trials, denominators, intervals and prespecified plans separately.
Remaining uncertainty: Unread or unverified materials do not mean zero effect, zero events, safety or new clinical certification.
Conditions for verification: Separate materials on endpoint-specific effects, interval levels, denominators and definitions
Why this condition is needed: An individual production condition recording original values, direct comparisons and application boundaries for the selected question
Application exceptions: Unread external materials, different comparisons or out-of-scope results do not substitute for fulfilled conditions, zero effect or safety.
Referenced methods: Fewer people with any repetition

Related sources R02

N18 · Are the review's 14 trials, the Carter trial and sibling sheets protected against double-counting?

Current findings: The original materials explicitly state that synthesis evidence is not double-counted as replication trials in the review's funding field. Subclaim sheets share the Carter materials and parent summary.
Verification status: Partly verified
Materials actually read: Summary read; external materials not read
Why unverified: Only the relevant information from the stored summary is recorded. Detailed original materials have not been read, and the original content review remains incomplete. The 14 trials are not declared a new independent replication count, and trials or participants are not added together. The overlap list of included trials has not been read.
Reason for missing information: The 14 trials are not declared a new independent replication count, and trials or participants are not added together. The overlap list of included trials has not been read.
Required materials and conditions: Relationships among original trials, synthesis reports, shared populations and endpoints
Materials to obtain first: The 14 trials are not declared a new independent replication count, and trials or participants are not added together. The overlap list of included trials has not been read.
Further research: Link original-trial lists, shared participants and report relationships from the review without newly certifying independence.
Remaining uncertainty: Unread or unverified materials do not mean zero effect, zero events, safety or new clinical certification.
Conditions for verification: Relationships among original trials, synthesis reports, shared populations and endpoints
Why this condition is needed: An individual production condition recording original values, direct comparisons and application boundaries for the selected question
Application exceptions: Unread external materials, different comparisons or out-of-scope results do not substitute for fulfilled conditions, zero effect or safety.
Referenced methods: Fewer people with any repetition

Related sources R01 R02

N19 · Are gaps in direct evidence for secondary results, subgroups and repeater analyses retained?

Current findings: The original materials focus on two coprimary results, an explanation about a small group of repeaters and the review.
Verification status: Unverified
Materials actually read: Summary read; external materials not read
Why unverified: Only the relevant information from the stored summary is recorded. Detailed original materials have not been read, and the original content review remains incomplete. Subgroup effects, denominators and P values absent from the original text, including those for sex, age and prior repetition, are not created. Explanations are not upgraded to proof of prespecified subgroup effects.
Reason for missing information: Subgroup effects, denominators and P values absent from the original text, including those for sex, age and prior repetition, are not created. Explanations are not upgraded to proof of prespecified subgroup effects.
Required materials and conditions: Outcome hierarchy, prespecified subgroups, interactions, original effects and denominators
Materials to obtain first: Subgroup effects, denominators and P values absent from the original text, including those for sex, age and prior repetition, are not created. Explanations are not upgraded to proof of prespecified subgroup effects.
Further research: Obtain original secondary-outcome and subgroup plans, interactions, denominators and multiplicity materials.
Remaining uncertainty: Unread or unverified materials do not mean zero effect, zero events, safety or new clinical certification.
Conditions for verification: Outcome hierarchy, prespecified subgroups, interactions, original effects and denominators
Why this condition is needed: An individual production condition recording original values, direct comparisons and application boundaries for the selected question
Application exceptions: Unread external materials, different comparisons or out-of-scope results do not substitute for fulfilled conditions, zero effect or safety.
Referenced methods: Fewer people with any repetition

Related sources R01

N20 · Are nonsignificant results and intervals distinguished from clinically important reductions in repetition?

Current findings: The preserved subclaim note states that the repeater CI, −7 to 3 percentage points, includes zero.
Verification status: Partly verified
Materials actually read: Summary read; external materials not read
Why unverified: Only the relevant information from the stored summary is recorded. Detailed original materials have not been read, and the original content review remains incomplete. The summary has no prespecified importance threshold, so exclusion of all meaningful effects, equivalence or universal lack of effect is not newly certified.
Reason for missing information: The summary has no prespecified importance threshold, so exclusion of all meaningful effects, equivalence or universal lack of effect is not newly certified.
Required materials and conditions: Importance thresholds, original between-group effects, intervals and prespecified plans
Materials to obtain first: The summary has no prespecified importance threshold, so exclusion of all meaningful effects, equivalence or universal lack of effect is not newly certified.
Further research: Link prespecified clinical thresholds and original plans for each endpoint, population and period when provided.
Remaining uncertainty: Unread or unverified materials do not mean zero effect, zero events, safety or new clinical certification.
Conditions for verification: Importance thresholds, original between-group effects, intervals and prespecified plans
Why this condition is needed: An individual production condition recording original values, direct comparisons and application boundaries for the selected question
Application exceptions: Unread external materials, different comparisons or out-of-scope results do not substitute for fulfilled conditions, zero effect or safety.
Referenced methods: Fewer people with any repetition

Related sources R01

N21 · Are repetition, event counts, suicide deaths and other clinical outcomes kept distinct?

Current findings: The stored summary records that the trial did not demonstrate fewer suicide deaths.
Verification status: Partly verified
Materials actually read: Summary read; external materials not read
Why unverified: Only the relevant information from the stored summary is recorded. Detailed original materials have not been read, and the original content review remains incomplete. Reduced repeat-event counts are not extended to fewer deaths, prevention of all repetition or benefits of other clinical treatments.
Reason for missing information: Reduced repeat-event counts are not extended to fewer deaths, prevention of all repetition or benefits of other clinical treatments.
Required materials and conditions: Direct distinction among people with repetition, events, deaths and other treatment outcomes
Materials to obtain first: Reduced repeat-event counts are not extended to fewer deaths, prevention of all repetition or benefits of other clinical treatments.
Further research: Link direct episode definitions, follow-up, denominators and effects separately for each clinical question.
Remaining uncertainty: Unread or unverified materials do not mean zero effect, zero events, safety or new clinical certification.
Conditions for verification: Direct distinction among people with repetition, events, deaths and other treatment outcomes
Why this condition is needed: An individual production condition recording original values, direct comparisons and application boundaries for the selected question
Application exceptions: Unread external materials, different comparisons or out-of-scope results do not substitute for fulfilled conditions, zero effect or safety.
Referenced methods: Fewer people with any repetition

Related sources R01 R02

N22 · Has guidance for widespread implementation or treatment replacement been avoided?

Current findings: The preserved text states that the review concluded widespread clinical implementation could not yet be recommended.
Verification status: Partly verified
Materials actually read: Summary read; external materials not read
Why unverified: Only the relevant information from the stored summary is recorded. Detailed original materials have not been read, and the original content review remains incomplete. This production is not guidance for personal contact, support actions, treatment changes or methods of repeating the behavior. A specific trial is not extended to every support approach.
Reason for missing information: This production is not guidance for personal contact, support actions, treatment changes or methods of repeating the behavior. A specific trial is not extended to every support approach.
Required materials and conditions: Application boundaries by population, intervention and comparator, and the original verdict context
Materials to obtain first: This production is not guidance for personal contact, support actions, treatment changes or methods of repeating the behavior. A specific trial is not extended to every support approach.
Further research: When direct materials on target populations and support are provided, link them separately for user review.
Remaining uncertainty: Unread or unverified materials do not mean zero effect, zero events, safety or new clinical certification.
Conditions for verification: Application boundaries by population, intervention and comparator, and the original verdict context
Why this condition is needed: An individual production condition recording original values, direct comparisons and application boundaries for the selected question
Application exceptions: Unread external materials, different comparisons or out-of-scope results do not substitute for fulfilled conditions, zero effect or safety.
Referenced methods: Fewer people with any repetition

Related sources R01 R02

N23 · Are public/nonprofit support and gaps in detailed involvement distinguished?

Current findings: The Carter study was supported by Hunter Area Health Service, NSW Health and NHMRC. The review records funding as varying among original trials.
Verification status: Partly verified
Materials actually read: Summary read; external materials not read
Why unverified: Only the relevant information from the stored summary is recorded. Detailed original materials have not been read, and the original content review remains incomplete. Funding labels alone do not establish absence of supplied products/services, employee authors or external analysis roles, and do not newly certify independence.
Reason for missing information: Funding labels alone do not establish absence of supplied products/services, employee authors or external analysis roles, and do not newly certify independence.
Required materials and conditions: Cash funding, supplied products/services, affiliated authors and external analysis roles
Materials to obtain first: Funding labels alone do not establish absence of supplied products/services, employee authors or external analysis roles, and do not newly certify independence.
Further research: Obtain original support, affiliation, study-role and analysis disclosures separately for the trial and review.
Remaining uncertainty: Unread or unverified materials do not mean zero effect, zero events, safety or new clinical certification.
Conditions for verification: Cash funding, supplied products/services, affiliated authors and external analysis roles
Why this condition is needed: An individual production condition recording original values, direct comparisons and application boundaries for the selected question
Application exceptions: Unread external materials, different comparisons or out-of-scope results do not substitute for fulfilled conditions, zero effect or safety.
Referenced methods: Fewer people with any repetition

Related sources R01 R02

N24 · Are absence of a separate adverse-event endpoint and unknown safety preserved?

Current findings: The stored summary records that safety was insufficiently assessed without a separate adverse-event endpoint; parent safety is unknown.
Verification status: Partly verified
Materials actually read: Summary read; external materials not read
Why unverified: Only the relevant information from the stored summary is recorded. Detailed original materials have not been read, and the original content review remains incomplete. This is not relabelled as zero adverse events, no serious harm or a safe intervention.
Reason for missing information: This is not relabelled as zero adverse events, no serious harm or a safe intervention.
Required materials and conditions: Original harm collection, events by group, exposure, denominators and relatedness data
Materials to obtain first: This is not relabelled as zero adverse events, no serious harm or a safe intervention.
Further research: Obtain original harm collection, events by group, exposure, denominators, relatedness and discontinuation materials.
Remaining uncertainty: Unread or unverified materials do not mean zero effect, zero events, safety or new clinical certification.
Conditions for verification: Original harm collection, events by group, exposure, denominators and relatedness data
Why this condition is needed: An individual production condition recording original values, direct comparisons and application boundaries for the selected question
Application exceptions: Unread external materials, different comparisons or out-of-scope results do not substitute for fulfilled conditions, zero effect or safety.
Referenced methods: Fewer people with any repetition

Related sources R01

N25 · Are inconclusive mortality results separated from long-term and rare harms?

Current findings: The trial did not establish reduced suicide mortality; the review records the suicide OR interval as 0.24–1.38.
Verification status: Partly verified
Materials actually read: Summary read; external materials not read
Why unverified: Only the relevant information from the stored summary is recorded. Detailed original materials have not been read, and the original content review remains incomplete. Nonsignificance is not described as absence of mortality risk. Death counts, harm rates and long-term safety absent from the original text are not created.
Reason for missing information: Nonsignificance is not described as absence of mortality risk. Death counts, harm rates and long-term safety absent from the original text are not created.
Required materials and conditions: Deaths, severity, periods, exposure, effect intervals and direct harm data
Materials to obtain first: Nonsignificance is not described as absence of mortality risk. Death counts, harm rates and long-term safety absent from the original text are not created.
Further research: Obtain endpoint-specific deaths, serious events, observation periods, exposure and direct harm data.
Remaining uncertainty: Unread or unverified materials do not mean zero effect, zero events, safety or new clinical certification.
Conditions for verification: Deaths, severity, periods, exposure, effect intervals and direct harm data
Why this condition is needed: An individual production condition recording original values, direct comparisons and application boundaries for the selected question
Application exceptions: Unread external materials, different comparisons or out-of-scope results do not substitute for fulfilled conditions, zero effect or safety.
Referenced methods: Fewer people with any repetition

Related sources R01 R02

N26 · Are gaps in harm replication and application to other populations, interventions and contacts retained?

Current findings: The original study involved a specific population after hospital treatment and a postcard intervention; the review covered various brief contacts.
Verification status: Unverified
Materials actually read: Summary read; external materials not read
Why unverified: Only the relevant information from the stored summary is recorded. Detailed original materials have not been read, and the original content review remains incomplete. Absence of harm or efficacy across all contacts and other populations is not newly established, and clinical implementation is not directed.
Reason for missing information: Absence of harm or efficacy across all contacts and other populations is not newly established, and clinical implementation is not directed.
Required materials and conditions: Direct harms by population, exposure and service, and shared-population relationships
Materials to obtain first: Absence of harm or efficacy across all contacts and other populations is not newly established, and clinical implementation is not directed.
Further research: Link direct materials by intervention and population, harm follow-up and report relationships separately.
Remaining uncertainty: Unread or unverified materials do not mean zero effect, zero events, safety or new clinical certification.
Conditions for verification: Direct harms by population, exposure and service, and shared-population relationships
Why this condition is needed: An individual production condition recording original values, direct comparisons and application boundaries for the selected question
Application exceptions: Unread external materials, different comparisons or out-of-scope results do not substitute for fulfilled conditions, zero effect or safety.
Referenced methods: Fewer people with any repetition

Related sources R01 R02

N27 · Are reading of summaries and external abstracts, full texts, registrations, protocols and SAP distinguished?

Current findings: The whole stored parent-verdict summary was read for production, linking the two PubMed URLs and the original ACTRN identifier.
Verification status: Partly verified
Materials actually read: Summary read; external materials not read
Why unverified: Only the relevant information from the stored summary is recorded. Detailed original materials have not been read, and the original content review remains incomplete. Existing links do not indicate completed external acquisition, reading or review. Full texts and plans for the review and original trial have not been read.
Reason for missing information: Existing links do not indicate completed external acquisition, reading or review. Full texts and plans for the review and original trial have not been read.
Required materials and conditions: Original URLs, stored summaries, identifiers and individual actual-access records
Materials to obtain first: Existing links do not indicate completed external acquisition, reading or review. Full texts and plans for the review and original trial have not been read.
Further research: Link user-provided materials to their individual types and access status.
Remaining uncertainty: Unread or unverified materials do not mean zero effect, zero events, safety or new clinical certification.
Conditions for verification: Original URLs, stored summaries, identifiers and individual actual-access records
Why this condition is needed: An individual production condition recording original values, direct comparisons and application boundaries for the selected question
Application exceptions: Unread external materials, different comparisons or out-of-scope results do not substitute for fulfilled conditions, zero effect or safety.
Referenced methods: Fewer people with any repetition

Related sources R01 R02

N28 · Are the cut-off, original subclaim/parent values, Korean/English texts, corrections and empty fields preserved?

Current findings: The cut-off 2026-08-26, empty correction and deliberation fields, Korean/English texts, parent C56, unknown safety, true split-coprimary flag and subclaim D are preserved.
Verification status: Partly verified
Materials actually read: Summary read; external materials not read
Why unverified: Only the relevant information from the stored summary is recorded. Detailed original materials have not been read, and the original content review remains incomplete. This production date is not substituted as a new clinical-verification date. Original cross-check wording is historical and does not indicate review completion here.
Reason for missing information: This production date is not substituted as a new clinical-verification date. Original cross-check wording is historical and does not indicate review completion here.
Required materials and conditions: Whole stored summary, selected verdict record and original verdict history
Materials to obtain first: This production date is not substituted as a new clinical-verification date. Original cross-check wording is historical and does not indicate review completion here.
Further research: Link new materials and decisions as separate events while preserving the entire original text.
Remaining uncertainty: Unread or unverified materials do not mean zero effect, zero events, safety or new clinical certification.
Conditions for verification: Whole stored summary, selected verdict record and original verdict history
Why this condition is needed: An individual production condition recording original values, direct comparisons and application boundaries for the selected question
Application exceptions: Unread external materials, different comparisons or out-of-scope results do not substitute for fulfilled conditions, zero effect or safety.
Referenced methods: Fewer people with any repetition

Related sources R01 R02

N29 · Are user-review indicators separated from production and independence status?

Current findings: Original review-pending/production-eligible indicators and boundary-review requirements are preserved as history. The original content review remains incomplete; active-pending and completion flags for model, content and boundary reviews are false.
Verification status: Partly verified
Materials actually read: Summary read; external materials not read
Why unverified: Only the relevant information from the stored summary is recorded. Detailed original materials have not been read, and the original content review remains incomplete. No new verdict, split or independence certification is made; added verdict units are 0 and the final independence count is not recorded.
Reason for missing information: No new verdict, split or independence certification is made; added verdict units are 0 and the final independence count is not recorded.
Required materials and conditions: Original candidate history and current production/review status
Materials to obtain first: No new verdict, split or independence certification is made; added verdict units are 0 and the final independence count is not recorded.
Further research: Reflect only user-provided decisions and materials as separate events.
Remaining uncertainty: Unread or unverified materials do not mean zero effect, zero events, safety or new clinical certification.
Conditions for verification: Original candidate history and current production/review status
Why this condition is needed: An individual production condition recording original values, direct comparisons and application boundaries for the selected question
Application exceptions: Unread external materials, different comparisons or out-of-scope results do not substitute for fulfilled conditions, zero effect or safety.
Referenced methods: Fewer people with any repetition

Related sources R01 R02