{ "schema_version": "chamgap-public-criteria-1.0", "title": "Raw or heat-treated ginger powder, 2 g/day × Reduction of muscle pain 24 hours after eccentric exercise", "language": "en", "translation_date": "2026-10-25", "criteria_version": "1.0", "criteria_date": "2026-10-06", "condition_origin": "Chamgap's own application conditions", "method_sources": [ { "id": "M03", "version": "Cochrane Handbook 6.5 (2024), chapter updated 2023-08", "url": "https://www.cochrane.org/authors/handbooks-and-manuals/handbook/current/chapter-03", "section": "§3.1, §3.2.1–3.2.3, MECIR C5/C7/C13", "official_principle": "Clearly record the question, eligibility conditions and reasons for changes, and distinguish variations in interventions.", "review_level": "Retained method-application records were reused. External originals were not reread and method content was not reassessed." }, { "id": "M04", "version": "Cochrane Handbook 6.5.1 (2025), chapter updated 2025-03", "url": "https://www.cochrane.org/authors/handbooks-and-manuals/handbook/current/chapter-04", "section": "§4.5, §4.6.1–4.6.3, MECIR C42", "official_principle": "Distinguish studies from reports and link them; do not omit a study solely because results are unreported.", "review_level": "Retained method-application records were reused. External originals were not reread and method content was not reassessed." }, { "id": "M08", "version": "Cochrane Handbook 6.5 (2024), chapter updated 2019-10", "url": "https://www.cochrane.org/authors/handbooks-and-manuals/handbook/current/chapter-08", "section": "§8.1–8.2.3, Table 8.2.a", "official_principle": "Define the outcome and effect of interest, then examine randomization, deviations, missing data, measurement and selective reporting.", "review_level": "Retained method-application records were reused. External originals were not reread and method content was not reassessed." }, { "id": "M15", "version": "Cochrane Handbook 6.5 (2024), chapter updated 2023-08", "url": "https://www.cochrane.org/authors/handbooks-and-manuals/handbook/current/chapter-15", "section": "§15.2.4, §15.3.1–15.3.3", "official_principle": "Distinguish effect estimates, intervals, importance and applicability. Sample size alone does not determine precision.", "review_level": "Retained method-application records were reused. External originals were not reread and method content was not reassessed." }, { "id": "M19", "version": "Cochrane Handbook 6.5 (2024), chapter updated 2019-10", "url": "https://www.cochrane.org/authors/handbooks-and-manuals/handbook/current/chapter-19", "section": "§19.1.2, §19.2.1–19.2.4", "official_principle": "Harm questions may require different designs, populations and follow-up from efficacy questions. Case reports do not establish incidence rates.", "review_level": "Retained method-application records were reused. External originals were not reread and method content was not reassessed." } ], "status_dictionary": { "Met": "Limited verification of the retained identity, observation or scope required by this item. This is separate from clinical sufficiency or full-text certification.", "Partly verified": "Some facts needed for the question are known, while the stated analysis, population, formulation, denominator or other details remain unverified.", "Unverified": "Direct information for this question has not been verified within the retained scope. This does not mean effect 0, no research, no harm or an unreviewed sheet.", "Not applicable": "An extension obligation outside the narrow question does not apply. This is not a replacement state for unread or unverified material.", "Not applicable (display alias)": "An alternate grey display label for Not applicable.", "Not read": "No current direct reading of external material. This is separate from reading the retained local summary.", "Conflicting data": "An actual inconsistency between reports under the same regimen; differences between questions alone do not establish a conflict." }, "requirements": [ { "item_id": "N01", "question_type": "Evidence condition", "question": "Which raw ginger-powder capsule comparison was selected as this sheet's single question?", "needed": "The current retained record and final boundary selection, with locations of formulation-specific results; later confirmation of formulation and comparator in the original protocol.", "role": "Required", "role_reason": "The parent question describes raw and heat-treated formulations together, so attribution of the raw ginger-powder capsule result needs to be traced as a separate question.", "application_exception": "This formulation-specific comparison is a derived question identifier, not an index in the original subclaim list. The other formulation is not deleted, and no new clinical score is assigned.", "criterion": "Link the selected formulation, oral 2 g/day, 11 days, healthy adults, placebo and 24-hour pain, while distinguishing the parent question, other formulation and original arrays.", "basis": "Existing method principles distinguish population, formulation, dose, timing, endpoint, comparison, denominators, overlap, support and harms in the retained reports. Detailed conditions are Chamgap's own application.", "condition_origin": "These are Chamgap in-house conditions developed with knowledge of the retained record for raw ginger powder, healthy adults, pain after eccentric exercise and matching placebo. They do not establish blinding, clinical-trial preregistration, official-tool certification, new independent clinical validation or a new formulation-specific grade.", "proposed_research": "Material needed: The current retained record and final boundary selection, with locations of formulation-specific results; later confirmation of formulation and comparator in the original protocol. This records needed materials; no new research was executed." }, { "item_id": "N02", "question_type": "Evidence condition", "question": "Is the raw ginger-powder capsule result being counted as replication by two independent research teams?", "needed": "Protocols, registration, participant overlap and recruitment periods for the two experiments, plus a map linking related reports.", "role": "Required", "role_reason": "Reports, experiments and team independence need to be distinguished so that the two sheets are not read as a count of independent replications.", "application_exception": "S01 contains two experiments, but this sheet selects one formulation versus placebo. The samples of 34/40 are not summed into unique participants, and overlap with S02 is not inferred.", "criterion": "Link the original statement that S01 contains two experiments in one paper by the same team to the different S02 regimen, leaving unconfirmed total unique participants unverified.", "basis": "Existing method principles distinguish population, formulation, dose, timing, endpoint, comparison, denominators, overlap, support and harms in the retained reports. Detailed conditions are Chamgap's own application.", "condition_origin": "These are Chamgap in-house conditions developed with knowledge of the retained record for raw ginger powder, healthy adults, pain after eccentric exercise and matching placebo. They do not establish blinding, clinical-trial preregistration, official-tool certification, new independent clinical validation or a new formulation-specific grade.", "proposed_research": "Material needed: Protocols, registration, participant overlap and recruitment periods for the two experiments, plus a map linking related reports. This records needed materials; no new research was executed." }, { "item_id": "N03", "question_type": "Evidence condition", "question": "What material was actually read when preparing the raw ginger-powder capsule sheet?", "needed": "The current retained summary, original source locations and identity, actual review date and separate material-specific access records.", "role": "Required", "role_reason": "It is necessary to distinguish actual reading of the local summary from reading the original abstract or full text.", "application_exception": "Reading the retained English summary is not reading the full English paper. Summary-reading links point to the retained source location and identity.", "criterion": "Read all Korean/English text, intervention/population details, axes, evidence, bibliography and corrections in the retained original summary, linking the locations and source identity.", "basis": "Existing method principles distinguish population, formulation, dose, timing, endpoint, comparison, denominators, overlap, support and harms in the retained reports. Detailed conditions are Chamgap's own application.", "condition_origin": "These are Chamgap in-house conditions developed with knowledge of the retained record for raw ginger powder, healthy adults, pain after eccentric exercise and matching placebo. They do not establish blinding, clinical-trial preregistration, official-tool certification, new independent clinical validation or a new formulation-specific grade.", "proposed_research": "Material needed: The current retained summary, original source locations and identity, actual review date and separate material-specific access records. This records needed materials; no new research was executed." }, { "item_id": "N04", "question_type": "Evidence condition", "question": "Do the raw ginger-powder capsule PubMed and DOI links also establish current reading of those materials?", "needed": "Actual acquired original/abstract, registration and protocol/SAP files, with success/failure, version and reading-date records.", "role": "Required", "role_reason": "Providing a safe link must not be mistaken for reading an abstract/full text or confirming that registration exists.", "application_exception": "External links are not visited in this work. An unidentified registration does not establish that the trial was unregistered or that registration is absent.", "criterion": "Distinguish entry points constructed from original bibliography URLs and DOIs from unacquired full text, registration and plans for each material. Do not label unattempted access as failed access.", "basis": "Existing method principles distinguish population, formulation, dose, timing, endpoint, comparison, denominators, overlap, support and harms in the retained reports. Detailed conditions are Chamgap's own application.", "condition_origin": "These are Chamgap in-house conditions developed with knowledge of the retained record for raw ginger powder, healthy adults, pain after eccentric exercise and matching placebo. They do not establish blinding, clinical-trial preregistration, official-tool certification, new independent clinical validation or a new formulation-specific grade.", "proposed_research": "Material needed: Actual acquired original/abstract, registration and protocol/SAP files, with success/failure, version and reading-date records. This records needed materials; no new research was executed." }, { "item_id": "N05", "question_type": "Evidence condition", "question": "How were the healthy adults contributing to the raw ginger-powder capsule result selected?", "needed": "Eligibility, recruitment setting, baseline characteristics, training status and formulation-specific population tables for each experiment.", "role": "Required", "role_reason": "The label healthy adults does not establish applicability to all ages, training levels or patients with injuries.", "application_exception": "The original samples of 34 and 40 describe populations; they are not assigned as the analysis denominator for this formulation.", "criterion": "Distinguish the verified description of healthy adult volunteers from unverified age, sex, exercise training, recruitment and exclusion details.", "basis": "Existing method principles distinguish population, formulation, dose, timing, endpoint, comparison, denominators, overlap, support and harms in the retained reports. Detailed conditions are Chamgap's own application.", "condition_origin": "These are Chamgap in-house conditions developed with knowledge of the retained record for raw ginger powder, healthy adults, pain after eccentric exercise and matching placebo. They do not establish blinding, clinical-trial preregistration, official-tool certification, new independent clinical validation or a new formulation-specific grade.", "proposed_research": "Material needed: Eligibility, recruitment setting, baseline characteristics, training status and formulation-specific population tables for each experiment. This records needed materials; no new research was executed." }, { "item_id": "N06", "question_type": "Evidence condition", "question": "How much of the actual formulation and ingredient specification of raw ginger-powder capsules is verified?", "needed": "Product/batch and raw-material specifications, drying/grinding and processing of raw powder, gingerol/shogaol batch content and actual content per capsule for the selected experiment.", "role": "Required", "role_reason": "Even with the same 2 g label, raw ginger-powder capsules cannot be substituted by heat-treated ginger-powder capsules, food, extracts or essential oils.", "application_exception": "Nominal powder mass is not converted into an active-ingredient dose, and another formulation's result does not replace batch verification.", "criterion": "Identify raw ginger-powder capsules as a distinct formulation, retaining uncertainty about drying/grinding, raw-material processing, gingerol/shogaol batch content, purity and actual capsule content.", "basis": "Existing method principles distinguish population, formulation, dose, timing, endpoint, comparison, denominators, overlap, support and harms in the retained reports. Detailed conditions are Chamgap's own application.", "condition_origin": "These are Chamgap in-house conditions developed with knowledge of the retained record for raw ginger powder, healthy adults, pain after eccentric exercise and matching placebo. They do not establish blinding, clinical-trial preregistration, official-tool certification, new independent clinical validation or a new formulation-specific grade.", "proposed_research": "Material needed: Product/batch and raw-material specifications, drying/grinding and processing of raw powder, gingerol/shogaol batch content and actual content per capsule for the selected experiment. This records needed materials; no new research was executed." }, { "item_id": "N07", "question_type": "Evidence condition", "question": "What are the 2 g/day, 11-day dosing and exercise/assessment schedules for raw ginger-powder capsules?", "needed": "Formulation-specific dosing logs, capsule frequency, first/last dose, exercise workload and assessment-time protocol.", "role": "Required", "role_reason": "It is necessary to avoid confusing single dosing with 11-day repeated dosing or replacing treatment duration with follow-up duration.", "application_exception": "Do not fill in a particular exercise day within the 11 days from outside the retained record. Timing of the single 2 g comparison remains separate context.", "criterion": "Link nominal oral 2 g/day for 11 days to the selected 24-hour assessment within 3 days of postexercise follow-up, without inferring the exact dosing/exercise schedule.", "basis": "Existing method principles distinguish population, formulation, dose, timing, endpoint, comparison, denominators, overlap, support and harms in the retained reports. Detailed conditions are Chamgap's own application.", "condition_origin": "These are Chamgap in-house conditions developed with knowledge of the retained record for raw ginger powder, healthy adults, pain after eccentric exercise and matching placebo. They do not establish blinding, clinical-trial preregistration, official-tool certification, new independent clinical validation or a new formulation-specific grade.", "proposed_research": "Material needed: Formulation-specific dosing logs, capsule frequency, first/last dose, exercise workload and assessment-time protocol. This records needed materials; no new research was executed." }, { "item_id": "N08", "question_type": "Evidence condition", "question": "Which placebo was compared with raw ginger-powder capsules, and in which direction?", "needed": "Composition, mass, capsule/taste/odor matching and actual allocated use of placebo in the relevant experiment.", "role": "Required", "role_reason": "It is necessary to avoid turning the result into a direct raw-versus-heat-treated comparison or an uncontrolled within-group change.", "application_exception": "The heat-treated ginger-powder capsule result is not used as placebo for raw ginger-powder capsules. A matching label alone does not establish successful sensory blinding.", "criterion": "Preserve the original direction of lower pain at 24 hours with the selected formulation versus matching placebo, while separately recording uncertainty about placebo composition and sensory matching.", "basis": "Existing method principles distinguish population, formulation, dose, timing, endpoint, comparison, denominators, overlap, support and harms in the retained reports. Detailed conditions are Chamgap's own application.", "condition_origin": "These are Chamgap in-house conditions developed with knowledge of the retained record for raw ginger powder, healthy adults, pain after eccentric exercise and matching placebo. They do not establish blinding, clinical-trial preregistration, official-tool certification, new independent clinical validation or a new formulation-specific grade.", "proposed_research": "Material needed: Composition, mass, capsule/taste/odor matching and actual allocated use of placebo in the relevant experiment. This records needed materials; no new research was executed." }, { "item_id": "N09", "question_type": "Evidence condition", "question": "Which scale and procedures measured pain intensity at 24 hours for raw ginger-powder capsules?", "needed": "The original pain scale, range/direction, resting/movement/palpation conditions, assessor and assessment-time report.", "role": "Required", "role_reason": "Different scales, pain-provoking conditions or time points must not be combined as the same effect.", "application_exception": "The original designation of 24 hours as the principal endpoint is separate from verification of a preregistered primary endpoint.", "criterion": "Specify pain intensity 24 hours after eccentric elbow-flexor exercise, describing unverified scale, range, conditions and assessor details.", "basis": "Existing method principles distinguish population, formulation, dose, timing, endpoint, comparison, denominators, overlap, support and harms in the retained reports. Detailed conditions are Chamgap's own application.", "condition_origin": "These are Chamgap in-house conditions developed with knowledge of the retained record for raw ginger powder, healthy adults, pain after eccentric exercise and matching placebo. They do not establish blinding, clinical-trial preregistration, official-tool certification, new independent clinical validation or a new formulation-specific grade.", "proposed_research": "Material needed: The original pain scale, range/direction, resting/movement/palpation conditions, assessor and assessment-time report. This records needed materials; no new research was executed." }, { "item_id": "N10", "question_type": "Evidence condition", "question": "Which measure, denominator and analysis do the raw ginger-powder capsule reports represent?", "needed": "Formulation-specific original pain results at 24 hours, absolute means/variances, percentage denominator/calculation, the definition of the SD label and CI/analysis tables.", "role": "Required", "role_reason": "The two formulations' 25%/23%, SD and P must not be exchanged or interpreted as direct formulation superiority.", "application_exception": "Do not rename SD as SMD without evidence, combine percentages with SD, or subtract another formulation's value.", "criterion": "Preserve 25%, −0.78 SD, P=.041 as the original report for this formulation versus placebo. Do not fill in formal percentage/SD measures, calculation, absolute units or CI.", "basis": "Existing method principles distinguish population, formulation, dose, timing, endpoint, comparison, denominators, overlap, support and harms in the retained reports. Detailed conditions are Chamgap's own application.", "condition_origin": "These are Chamgap in-house conditions developed with knowledge of the retained record for raw ginger powder, healthy adults, pain after eccentric exercise and matching placebo. They do not establish blinding, clinical-trial preregistration, official-tool certification, new independent clinical validation or a new formulation-specific grade.", "proposed_research": "Material needed: Formulation-specific original pain results at 24 hours, absolute means/variances, percentage denominator/calculation, the definition of the SD label and CI/analysis tables. This records needed materials; no new research was executed." }, { "item_id": "N11", "question_type": "Evidence condition", "question": "Among the samples of 34 and 40, what are the randomized, analyzed and completed denominators for raw ginger-powder capsules?", "needed": "Formulation-specific CONSORT flow, randomized/measured/analyzed/completed counts, withdrawal reasons and handling, and original result CI.", "role": "Required", "role_reason": "Do not fill the selected effect's sample basis and precision using another formulation's sample or a completed-participant count.", "application_exception": "Do not assign 34 to raw and 40 to heat-treated powder from source order, or generate a total, equal arm split or ITT population.", "criterion": "Retain the original samples of 34 and 40, distinguishing unverified formulation mapping, per-arm randomized/analyzed/completed/missing counts and CI.", "basis": "Existing method principles distinguish population, formulation, dose, timing, endpoint, comparison, denominators, overlap, support and harms in the retained reports. Detailed conditions are Chamgap's own application.", "condition_origin": "These are Chamgap in-house conditions developed with knowledge of the retained record for raw ginger powder, healthy adults, pain after eccentric exercise and matching placebo. They do not establish blinding, clinical-trial preregistration, official-tool certification, new independent clinical validation or a new formulation-specific grade.", "proposed_research": "Material needed: Formulation-specific CONSORT flow, randomized/measured/analyzed/completed counts, withdrawal reasons and handling, and original result CI. This records needed materials; no new research was executed." }, { "item_id": "N12", "question_type": "Evidence condition", "question": "What are the evidence date and actual verification scope of this raw ginger-powder capsule conversion?", "needed": "The retained review date, current input identity, actual actions in this work and later authorized search/correction/retraction-check records.", "role": "Required", "role_reason": "The retained-summary conversion must not be presented as a current complete literature or registration search.", "application_exception": "No search in this work does not mean 0 studies. A historical verdict date is not inherited as a current external-access date.", "criterion": "Distinguish the original verdict date from this review date, accurately recording that new searching, retraction/correction and registration checks were not performed.", "basis": "Existing method principles distinguish population, formulation, dose, timing, endpoint, comparison, denominators, overlap, support and harms in the retained reports. Detailed conditions are Chamgap's own application.", "condition_origin": "These are Chamgap in-house conditions developed with knowledge of the retained record for raw ginger powder, healthy adults, pain after eccentric exercise and matching placebo. They do not establish blinding, clinical-trial preregistration, official-tool certification, new independent clinical validation or a new formulation-specific grade.", "proposed_research": "Material needed: The retained review date, current input identity, actual actions in this work and later authorized search/correction/retraction-check records. This records needed materials; no new research was executed." }, { "item_id": "N13", "question_type": "Evidence condition", "question": "How much is verified about funding, product support and author interests in the raw ginger-powder capsule experiments?", "needed": "Original funding, product-support, author-role/employment, patent and COI statements, with institutional/family links.", "role": "Supplementary; required for independence claims", "role_reason": "Recorded support must not automatically exclude the result or turn another formulation's result into independent funding or independent-team replication.", "application_exception": "Preserve the historical description of industry support without assigning a new bias grade or an exact bias magnitude.", "criterion": "Retain McCormick Science Institute support and the same-team relationship, separately recording unverified product support, employment, patents and declared COI.", "basis": "Existing method principles distinguish population, formulation, dose, timing, endpoint, comparison, denominators, overlap, support and harms in the retained reports. Detailed conditions are Chamgap's own application.", "condition_origin": "These are Chamgap in-house conditions developed with knowledge of the retained record for raw ginger powder, healthy adults, pain after eccentric exercise and matching placebo. They do not establish blinding, clinical-trial preregistration, official-tool certification, new independent clinical validation or a new formulation-specific grade.", "proposed_research": "Material needed: Original funding, product-support, author-role/employment, patent and COI statements, with institutional/family links. This records needed materials; no new research was executed." }, { "item_id": "N14", "question_type": "Evidence condition", "question": "What were the actual allocation and concealment procedures for raw ginger-powder capsules versus placebo?", "needed": "Group structure, sequence generation, concealment, baseline balance and implementation records for the selected experiment.", "role": "Required", "role_reason": "An RCT label alone must not be taken to resolve allocation or confounding issues.", "application_exception": "Do not inherit the S02 crossover design into S01 or automatically fill in parallel/crossover details for S01 while they remain unverified.", "criterion": "Distinguish the recorded randomized, double-blind, placebo-controlled design from unverified formulation-specific design, sequence generation, concealment and baseline tables.", "basis": "Existing method principles distinguish population, formulation, dose, timing, endpoint, comparison, denominators, overlap, support and harms in the retained reports. Detailed conditions are Chamgap's own application.", "condition_origin": "These are Chamgap in-house conditions developed with knowledge of the retained record for raw ginger powder, healthy adults, pain after eccentric exercise and matching placebo. They do not establish blinding, clinical-trial preregistration, official-tool certification, new independent clinical validation or a new formulation-specific grade.", "proposed_research": "Material needed: Group structure, sequence generation, concealment, baseline balance and implementation records for the selected experiment. This records needed materials; no new research was executed." }, { "item_id": "N15", "question_type": "Evidence condition", "question": "Can adherence, co-interventions and rescue-analgesic differences between raw ginger-powder capsule and placebo groups be distinguished?", "needed": "Per-arm dosing adherence, exercise implementation, diet/other supplements, rescue analgesics, changes/deviations and their analytical handling.", "role": "Required", "role_reason": "Differences in concurrent treatment or exercise workload must not be attributed to the powder effect.", "application_exception": "Missing information does not mean co-interventions/rescue treatments were absent or identical between arms.", "criterion": "Link actual formulation-specific dosing/exercise adherence, co-interventions/analgesics and deviation handling to observed pain.", "basis": "Existing method principles distinguish population, formulation, dose, timing, endpoint, comparison, denominators, overlap, support and harms in the retained reports. Detailed conditions are Chamgap's own application.", "condition_origin": "These are Chamgap in-house conditions developed with knowledge of the retained record for raw ginger powder, healthy adults, pain after eccentric exercise and matching placebo. They do not establish blinding, clinical-trial preregistration, official-tool certification, new independent clinical validation or a new formulation-specific grade.", "proposed_research": "Material needed: Per-arm dosing adherence, exercise implementation, diet/other supplements, rescue analgesics, changes/deviations and their analytical handling. This records needed materials; no new research was executed." }, { "item_id": "N16", "question_type": "Evidence condition", "question": "Who was blinded during subjective pain assessment for raw ginger-powder capsules, and were sensory differences checked?", "needed": "Participant/assessor/analyst blinding by role, taste/odor/capsule differences, blinding assessment and measurement procedures.", "role": "Required", "role_reason": "Expectancy and measurement differences can affect interpretation of subjective pain, so the actual blinded roles need to be identified.", "application_exception": "Unverified blinding is not confirmed blinding failure, and a matching-placebo label does not replace a success assessment.", "criterion": "Distinguish the double-blind label from actual verification of participant/assessor roles, sensory matching and blinding success.", "basis": "Existing method principles distinguish population, formulation, dose, timing, endpoint, comparison, denominators, overlap, support and harms in the retained reports. Detailed conditions are Chamgap's own application.", "condition_origin": "These are Chamgap in-house conditions developed with knowledge of the retained record for raw ginger powder, healthy adults, pain after eccentric exercise and matching placebo. They do not establish blinding, clinical-trial preregistration, official-tool certification, new independent clinical validation or a new formulation-specific grade.", "proposed_research": "Material needed: Participant/assessor/analyst blinding by role, taste/odor/capsule differences, blinding assessment and measurement procedures. This records needed materials; no new research was executed." }, { "item_id": "N17", "question_type": "Evidence condition", "question": "Does the reported raw ginger-powder capsule effect represent an assignment effect or an adherence effect?", "needed": "Planned/actual analysis populations, ITT/PP definitions, formulation-specific models, adjustment, repeated measures and original missing-data handling tables.", "role": "Required", "role_reason": "Even the same P value must not transfer results from different analyses or populations as the same effect.", "application_exception": "Generic English denominator/result wording that mentions separation or verification does not establish actual ITT or model verification.", "criterion": "Specify ITT/PP, analysis population, repeated-measures/between-group comparisons and adjustment/missing-data handling only to the extent verified, retaining unknowns.", "basis": "Existing method principles distinguish population, formulation, dose, timing, endpoint, comparison, denominators, overlap, support and harms in the retained reports. Detailed conditions are Chamgap's own application.", "condition_origin": "These are Chamgap in-house conditions developed with knowledge of the retained record for raw ginger powder, healthy adults, pain after eccentric exercise and matching placebo. They do not establish blinding, clinical-trial preregistration, official-tool certification, new independent clinical validation or a new formulation-specific grade.", "proposed_research": "Material needed: Planned/actual analysis populations, ITT/PP definitions, formulation-specific models, adjustment, repeated measures and original missing-data handling tables. This records needed materials; no new research was executed." }, { "item_id": "N18", "question_type": "Evidence condition", "question": "Can uncertainty and importance of the raw ginger-powder capsule pain difference at 24 hours be assessed?", "needed": "Formulation-specific effect CI, scale-specific variance, analysis denominator, MID/important-difference evidence and the effect definition.", "role": "Required", "role_reason": "A significant P, an SD label or a description of a small sample must not create a new sufficiency/precision verdict.", "application_exception": "Do not impose common minimum participant, trial or duration thresholds, or recalculate CI from SD/P.", "criterion": "Relate precision and importance only when verified CI, variance and justified important-difference criteria are available. Do not determine sufficiency from P or a historical effect-size description.", "basis": "Existing method principles distinguish population, formulation, dose, timing, endpoint, comparison, denominators, overlap, support and harms in the retained reports. Detailed conditions are Chamgap's own application.", "condition_origin": "These are Chamgap in-house conditions developed with knowledge of the retained record for raw ginger powder, healthy adults, pain after eccentric exercise and matching placebo. They do not establish blinding, clinical-trial preregistration, official-tool certification, new independent clinical validation or a new formulation-specific grade.", "proposed_research": "Material needed: Formulation-specific effect CI, scale-specific variance, analysis denominator, MID/important-difference evidence and the effect definition. This records needed materials; no new research was executed." }, { "item_id": "N19", "question_type": "Evidence condition", "question": "Were the raw ginger-powder capsule endpoint at 24 hours and its analysis specified in advance?", "needed": "Exact trial registration, prospective protocol/SAP, endpoint/time/formulation testing hierarchy, multiplicity handling and reasons for changes.", "role": "Required", "role_reason": "The information gap needed to examine favorable time-point or analysis selection must remain visible.", "application_exception": "Unidentified registration is not proof of an unregistered trial. PMID/DOI does not replace registration/SAP verification.", "criterion": "Confirm only portions actually compared between registration/protocol/SAP and reporting. Do not inherit the principal-endpoint field or P axis as confirmation of prospective planning.", "basis": "Existing method principles distinguish population, formulation, dose, timing, endpoint, comparison, denominators, overlap, support and harms in the retained reports. Detailed conditions are Chamgap's own application.", "condition_origin": "These are Chamgap in-house conditions developed with knowledge of the retained record for raw ginger powder, healthy adults, pain after eccentric exercise and matching placebo. They do not establish blinding, clinical-trial preregistration, official-tool certification, new independent clinical validation or a new formulation-specific grade.", "proposed_research": "Material needed: Exact trial registration, prospective protocol/SAP, endpoint/time/formulation testing hierarchy, multiplicity handling and reasons for changes. This records needed materials; no new research was executed." }, { "item_id": "N20", "question_type": "Evidence condition", "question": "Can the heat-treated ginger-powder capsule result be read as independent reproduction of raw ginger-powder capsules or a superiority comparison?", "needed": "Formulation-specific experiment regimens, direct head-to-head analyses and direct evidence for the same formulation from other teams.", "role": "Required", "role_reason": "Creating two sheets or having two different numbers does not establish independent replication or heat-treated superiority.", "application_exception": "Do not subtract the two values to establish superiority or equivalence. Whether the original paper reported a direct comparison has not been verified in this work.", "criterion": "Retain the other formulation's placebo comparison in the same paper/team as context, without adding it as independent-team direct replication of the selected formulation or a direct between-formulation effect.", "basis": "Existing method principles distinguish population, formulation, dose, timing, endpoint, comparison, denominators, overlap, support and harms in the retained reports. Detailed conditions are Chamgap's own application.", "condition_origin": "These are Chamgap in-house conditions developed with knowledge of the retained record for raw ginger powder, healthy adults, pain after eccentric exercise and matching placebo. They do not establish blinding, clinical-trial preregistration, official-tool certification, new independent clinical validation or a new formulation-specific grade.", "proposed_research": "Material needed: Formulation-specific experiment regimens, direct head-to-head analyses and direct evidence for the same formulation from other teams. This records needed materials; no new research was executed." }, { "item_id": "N21", "question_type": "Evidence condition", "question": "How does the single 2 g crossover trial S02 relate to the raw ginger-powder capsule, 11-day question?", "needed": "The exact S02 formulation, dosing/exercise timing, washout/periods, pain time points, analysis/CI and participant flow.", "role": "Required", "role_reason": "The unfavorable observation must be retained while avoiding mixing a different regimen into direct replication of the selected formulation.", "application_exception": "Do not infer the 25 people as each period's denominator, completers or formulation-specific counts. Retain the Korean immediately-before and English around wording without inventing harmonized exact timing.", "criterion": "Retain the single/repeated dosing, timing and endpoint differences and the negative observation. Do not turn them into proof of no effect/equivalence or conflicting results under the same regimen.", "basis": "Existing method principles distinguish population, formulation, dose, timing, endpoint, comparison, denominators, overlap, support and harms in the retained reports. Detailed conditions are Chamgap's own application.", "condition_origin": "These are Chamgap in-house conditions developed with knowledge of the retained record for raw ginger powder, healthy adults, pain after eccentric exercise and matching placebo. They do not establish blinding, clinical-trial preregistration, official-tool certification, new independent clinical validation or a new formulation-specific grade.", "proposed_research": "Material needed: The exact S02 formulation, dosing/exercise timing, washout/periods, pain time points, analysis/CI and participant flow. This records needed materials; no new research was executed." }, { "item_id": "N22", "question_type": "Evidence condition", "question": "Must this 24-hour question also establish the optimal dose of raw ginger-powder capsules?", "needed": "Direct formulation-specific dose comparisons and analysis/safety material, distinguished from material required for the current narrow regimen.", "role": "Supplementary; required for the relevant extension question", "role_reason": "Do not automatically append an optimal-dose claim; retain the review scope of the selected 24-hour result.", "application_exception": "Not applicable applies only to the obligation to require extension research as a prerequisite for the current result. Direct evidence remains unverified.", "criterion": "Do not require proof of an optimal dose as mandatory for the narrow 24-hour, healthy-adult, 2 g/day for 11 days question. Separately retain that the relevant material remains unverified.", "basis": "Existing method principles distinguish population, formulation, dose, timing, endpoint, comparison, denominators, overlap, support and harms in the retained reports. Detailed conditions are Chamgap's own application.", "condition_origin": "These are Chamgap in-house conditions developed with knowledge of the retained record for raw ginger powder, healthy adults, pain after eccentric exercise and matching placebo. They do not establish blinding, clinical-trial preregistration, official-tool certification, new independent clinical validation or a new formulation-specific grade.", "proposed_research": "Material needed: Direct formulation-specific dose comparisons and analysis/safety material, distinguished from material required for the current narrow regimen. This records needed materials; no new research was executed." }, { "item_id": "N23", "question_type": "Evidence condition", "question": "Must this question also establish long-term pain effects after stopping raw ginger-powder capsules?", "needed": "Post-discontinuation/long-term follow-up, exposure logs, time-specific pain estimates and missing-data material, distinguished from material required for the current narrow regimen.", "role": "Supplementary; required for the relevant extension question", "role_reason": "Do not automatically append a persistence-after-stopping claim; retain the review scope of the selected 24-hour result.", "application_exception": "Not applicable applies only to the obligation to require extension research as a prerequisite for the current result. Direct evidence remains unverified.", "criterion": "Do not require proof of persistence after stopping as mandatory for the narrow 24-hour, healthy-adult, 2 g/day for 11 days question. Separately retain that the relevant material remains unverified.", "basis": "Existing method principles distinguish population, formulation, dose, timing, endpoint, comparison, denominators, overlap, support and harms in the retained reports. Detailed conditions are Chamgap's own application.", "condition_origin": "These are Chamgap in-house conditions developed with knowledge of the retained record for raw ginger powder, healthy adults, pain after eccentric exercise and matching placebo. They do not establish blinding, clinical-trial preregistration, official-tool certification, new independent clinical validation or a new formulation-specific grade.", "proposed_research": "Material needed: Post-discontinuation/long-term follow-up, exposure logs, time-specific pain estimates and missing-data material, distinguished from material required for the current narrow regimen. This records needed materials; no new research was executed." }, { "item_id": "N24", "question_type": "Evidence condition", "question": "Must this question also establish raw ginger-powder capsule effects in particular age or training subgroups?", "needed": "Prospective subgroup plans, composition/denominators, interaction tests and direct estimates, distinguished from material required for the current narrow regimen.", "role": "Supplementary; required for the relevant extension question", "role_reason": "Do not automatically append a particular-subgroup claim; retain the review scope of the selected 24-hour result.", "application_exception": "Not applicable applies only to the obligation to require extension research as a prerequisite for the current result. Direct evidence remains unverified.", "criterion": "Do not require proof of particular subgroup effects as mandatory for the narrow 24-hour, healthy-adult, 2 g/day for 11 days question. Separately retain that the relevant material remains unverified.", "basis": "Existing method principles distinguish population, formulation, dose, timing, endpoint, comparison, denominators, overlap, support and harms in the retained reports. Detailed conditions are Chamgap's own application.", "condition_origin": "These are Chamgap in-house conditions developed with knowledge of the retained record for raw ginger powder, healthy adults, pain after eccentric exercise and matching placebo. They do not establish blinding, clinical-trial preregistration, official-tool certification, new independent clinical validation or a new formulation-specific grade.", "proposed_research": "Material needed: Prospective subgroup plans, composition/denominators, interaction tests and direct estimates, distinguished from material required for the current narrow regimen. This records needed materials; no new research was executed." }, { "item_id": "N25", "question_type": "Evidence condition", "question": "Is the raw ginger-powder capsule pain result at 24 hours extended into guaranteed recovery or prevention of muscle injury?", "needed": "Direct clinical endpoints, duration/denominators, comparisons and precision if recovery or injury prevention is claimed.", "role": "Supplementary; required for extension to recovery or injury prevention", "role_reason": "A symptom difference must not automatically be promoted to other functions, events or guarantees.", "application_exception": "Not applicable applies only to the obligation to prove a separate clinical extension. Unverified recovery/prevention material is not changed into evidence of no effect.", "criterion": "Distinguish pain intensity itself from the clinical questions of exercise recovery/injury prevention. Do not require a separate event trial as mandatory for the narrow pain result.", "basis": "Existing method principles distinguish population, formulation, dose, timing, endpoint, comparison, denominators, overlap, support and harms in the retained reports. Detailed conditions are Chamgap's own application.", "condition_origin": "These are Chamgap in-house conditions developed with knowledge of the retained record for raw ginger powder, healthy adults, pain after eccentric exercise and matching placebo. They do not establish blinding, clinical-trial preregistration, official-tool certification, new independent clinical validation or a new formulation-specific grade.", "proposed_research": "Material needed: Direct clinical endpoints, duration/denominators, comparisons and precision if recovery or injury prevention is claimed. This records needed materials; no new research was executed." }, { "item_id": "N26", "question_type": "Evidence condition", "question": "Which adverse events were collected, and how, in the raw ginger-powder capsule experiment?", "needed": "Formulation-specific original AE definitions, systematic/spontaneous collection, diagnosis/severity and discontinuation tables and protocol.", "role": "Supplementary; required for harm or safety questions", "role_reason": "An efficacy summary or general caution must not replace actual event counts or establish safety.", "application_exception": "Unverified information in the summary does not establish nonreporting throughout the original paper. Insufficient harm verification is not a reason to delete the retained efficacy report.", "criterion": "Distinguish original caution wording from actual AE definitions, collection, severity and discontinuation in the relevant experiment. Do not infer that events were absent.", "basis": "Existing method principles distinguish population, formulation, dose, timing, endpoint, comparison, denominators, overlap, support and harms in the retained reports. Detailed conditions are Chamgap's own application.", "condition_origin": "These are Chamgap in-house conditions developed with knowledge of the retained record for raw ginger powder, healthy adults, pain after eccentric exercise and matching placebo. They do not establish blinding, clinical-trial preregistration, official-tool certification, new independent clinical validation or a new formulation-specific grade.", "proposed_research": "Material needed: Formulation-specific original AE definitions, systematic/spontaneous collection, diagnosis/severity and discontinuation tables and protocol. This records needed materials; no new research was executed." }, { "item_id": "N27", "question_type": "Evidence condition", "question": "Is the timing of raw ginger-powder capsule exposure, harm onset, stopping and recovery verified?", "needed": "Individual AE onset/recovery times, dosing logs, stopping/rechallenge and follow-up duration.", "role": "Supplementary; required for harm timing or causality", "role_reason": "The efficacy regimen of 11 days of dosing and 3 days of follow-up must not be converted into a complete harm timeline.", "application_exception": "No event record does not mean latency, stopping or rechallenge did not occur.", "criterion": "Distinguish dosing duration from actual event onset/latency, stopping, recovery and rechallenge. Temporal sequence alone does not establish causality.", "basis": "Existing method principles distinguish population, formulation, dose, timing, endpoint, comparison, denominators, overlap, support and harms in the retained reports. Detailed conditions are Chamgap's own application.", "condition_origin": "These are Chamgap in-house conditions developed with knowledge of the retained record for raw ginger powder, healthy adults, pain after eccentric exercise and matching placebo. They do not establish blinding, clinical-trial preregistration, official-tool certification, new independent clinical validation or a new formulation-specific grade.", "proposed_research": "Material needed: Individual AE onset/recovery times, dosing logs, stopping/rechallenge and follow-up duration. This records needed materials; no new research was executed." }, { "item_id": "N28", "question_type": "Evidence condition", "question": "Were adverse-event differences between raw ginger-powder capsules and placebo directly compared?", "needed": "Actual AE people/event counts, collection periods/methods, between-group estimates and CI for formulation/placebo arms.", "role": "Supplementary; required for comparative harms", "role_reason": "The placebo-controlled efficacy label must not be inherited as verification of a harm comparison.", "application_exception": "The comparator may be known while harm tables remain unverified. Do not fill them with external background incidence.", "criterion": "Separate the efficacy placebo comparison from actual per-arm harm collection/estimation. Do not infer risk differences or incidence.", "basis": "Existing method principles distinguish population, formulation, dose, timing, endpoint, comparison, denominators, overlap, support and harms in the retained reports. Detailed conditions are Chamgap's own application.", "condition_origin": "These are Chamgap in-house conditions developed with knowledge of the retained record for raw ginger powder, healthy adults, pain after eccentric exercise and matching placebo. They do not establish blinding, clinical-trial preregistration, official-tool certification, new independent clinical validation or a new formulation-specific grade.", "proposed_research": "Material needed: Actual AE people/event counts, collection periods/methods, between-group estimates and CI for formulation/placebo arms. This records needed materials; no new research was executed." }, { "item_id": "N29", "question_type": "Evidence condition", "question": "Are there exposure denominators and event counts to calculate harm frequency for raw ginger-powder capsules?", "needed": "Formulation-specific exposure/safety-analysis counts, AE people and event counts, exposure time, follow-up losses and recruitment/reporting systems.", "role": "Supplementary; required for harm frequency", "role_reason": "Reported trial sample sizes must not be misread as incidence denominators.", "application_exception": "Do not use the 34/40 samples, whose efficacy mapping is itself unverified, as incidence denominators or add the single-dose trial's 25 people.", "criterion": "Use only reports linking formulation-specific exposure/safety-analysis denominators, people/event counts and time. Do not inherit 34/40 as harm denominators.", "basis": "Existing method principles distinguish population, formulation, dose, timing, endpoint, comparison, denominators, overlap, support and harms in the retained reports. Detailed conditions are Chamgap's own application.", "condition_origin": "These are Chamgap in-house conditions developed with knowledge of the retained record for raw ginger powder, healthy adults, pain after eccentric exercise and matching placebo. They do not establish blinding, clinical-trial preregistration, official-tool certification, new independent clinical validation or a new formulation-specific grade.", "proposed_research": "Material needed: Formulation-specific exposure/safety-analysis counts, AE people and event counts, exposure time, follow-up losses and recruitment/reporting systems. This records needed materials; no new research was executed." }, { "item_id": "N30", "question_type": "Evidence condition", "question": "Are concomitant medicines, baseline conditions and other exposures that might explain harms with raw ginger-powder capsules verified?", "needed": "Concomitant medicines/supplements, baseline GI conditions, exercise workload/lifestyle exposures, alternative-explanation assessment and adjustment material.", "role": "Supplementary; required for causal or comparative harms", "role_reason": "A general interaction caution must not be turned into an observed trial interaction or attribution to one exposure.", "application_exception": "Unverified alternatives do not mean no alternative cause existed. Do not generate personal dosing instructions.", "criterion": "Attribute harms only to the extent actual concurrent exposures, baseline symptoms and alternative explanations/adjustment have been verified.", "basis": "Existing method principles distinguish population, formulation, dose, timing, endpoint, comparison, denominators, overlap, support and harms in the retained reports. Detailed conditions are Chamgap's own application.", "condition_origin": "These are Chamgap in-house conditions developed with knowledge of the retained record for raw ginger powder, healthy adults, pain after eccentric exercise and matching placebo. They do not establish blinding, clinical-trial preregistration, official-tool certification, new independent clinical validation or a new formulation-specific grade.", "proposed_research": "Material needed: Concomitant medicines/supplements, baseline GI conditions, exercise workload/lifestyle exposures, alternative-explanation assessment and adjustment material. This records needed materials; no new research was executed." }, { "item_id": "N31", "question_type": "Evidence condition", "question": "What are the reporting selection, detection differences and follow-up losses in raw ginger-powder capsule harm material?", "needed": "AE collection tools, scope of complete event disclosure, per-arm detection/withdrawals and safety missing-data handling.", "role": "Supplementary; required for review of harm material", "role_reason": "Reporting a pain effect and completely reporting safety material are distinct facts.", "application_exception": "Unverified possible bias is not converted into a definite bias magnitude or invalidation of the result.", "criterion": "Verify collection/selection, disclosure of all events, per-arm detection and follow-up losses. Do not turn summary-level unknowns into absence of events.", "basis": "Existing method principles distinguish population, formulation, dose, timing, endpoint, comparison, denominators, overlap, support and harms in the retained reports. Detailed conditions are Chamgap's own application.", "condition_origin": "These are Chamgap in-house conditions developed with knowledge of the retained record for raw ginger powder, healthy adults, pain after eccentric exercise and matching placebo. They do not establish blinding, clinical-trial preregistration, official-tool certification, new independent clinical validation or a new formulation-specific grade.", "proposed_research": "Material needed: AE collection tools, scope of complete event disclosure, per-arm detection/withdrawals and safety missing-data handling. This records needed materials; no new research was executed." }, { "item_id": "N32", "question_type": "Evidence condition", "question": "Was the same harm with raw ginger-powder capsules recorded in other independent material?", "needed": "Actual harm source material for the selected formulation, event/study families, independence/re-citation and contrary records.", "role": "Supplementary; required for repeated-harm claims", "role_reason": "Two same-team pain experiments or two sheets must not be counted as independent safety replication.", "application_exception": "No new harm search is performed in this work. Unverified material is not changed into 0 replications or no events.", "criterion": "Link actual event/harm-study families, re-citation and exposure matching only to the extent verified. Do not count pain experiments as harm replications.", "basis": "Existing method principles distinguish population, formulation, dose, timing, endpoint, comparison, denominators, overlap, support and harms in the retained reports. Detailed conditions are Chamgap's own application.", "condition_origin": "These are Chamgap in-house conditions developed with knowledge of the retained record for raw ginger powder, healthy adults, pain after eccentric exercise and matching placebo. They do not establish blinding, clinical-trial preregistration, official-tool certification, new independent clinical validation or a new formulation-specific grade.", "proposed_research": "Material needed: Actual harm source material for the selected formulation, event/study families, independence/re-citation and contrary records. This records needed materials; no new research was executed." }, { "item_id": "N33", "question_type": "Evidence condition", "question": "Must a short-term healthy-adult pain question about raw ginger-powder capsules require proof of all long-term, rare and vulnerable-population harms?", "needed": "Direct long-term exposure, rare-event, vulnerable-population/interaction material and suitable designs if the harm scope is extended.", "role": "Supplementary; required for long-term or vulnerable-population harm questions", "role_reason": "Short-term efficacy material must not be turned into overall safety or make all extension research mandatory for the current pain sheet.", "application_exception": "Not applicable applies only to the extension-proof obligation. Direct long-term, rare and vulnerable-population information remains unverified, and general caution is retained.", "criterion": "Do not require proof of every long-term, rare or vulnerable-population harm to prepare the current narrow efficacy question, while retaining the unverified status of that direct information.", "basis": "Existing method principles distinguish population, formulation, dose, timing, endpoint, comparison, denominators, overlap, support and harms in the retained reports. Detailed conditions are Chamgap's own application.", "condition_origin": "These are Chamgap in-house conditions developed with knowledge of the retained record for raw ginger powder, healthy adults, pain after eccentric exercise and matching placebo. They do not establish blinding, clinical-trial preregistration, official-tool certification, new independent clinical validation or a new formulation-specific grade.", "proposed_research": "Material needed: Direct long-term exposure, rare-event, vulnerable-population/interaction material and suitable designs if the harm scope is extended. This records needed materials; no new research was executed." }, { "item_id": "N34", "question_type": "Evidence condition", "question": "Is the original raw ginger-powder capsule caution wording being turned into incidence, causal attribution or safety certification?", "needed": "Design, comparison, denominator, time and alternative explanations in original harm material, and the attribution/interpretive scope of caution wording.", "role": "Supplementary; required for harm interpretation", "role_reason": "General caution must not be promoted into confirmed experimental AEs or a safety grade.", "application_exception": "This retained-summary conversion is not execution of a causality tool, a new safety verdict or dosing instructions. Uncertain cautions are not deleted.", "criterion": "Separate the historical parent C50/Caution wording from unverified actual harm observations. Do not create personal dosing instructions or determinate incidence/causal claims.", "basis": "Existing method principles distinguish population, formulation, dose, timing, endpoint, comparison, denominators, overlap, support and harms in the retained reports. Detailed conditions are Chamgap's own application.", "condition_origin": "These are Chamgap in-house conditions developed with knowledge of the retained record for raw ginger powder, healthy adults, pain after eccentric exercise and matching placebo. They do not establish blinding, clinical-trial preregistration, official-tool certification, new independent clinical validation or a new formulation-specific grade.", "proposed_research": "Material needed: Design, comparison, denominator, time and alternative explanations in original harm material, and the attribution/interpretive scope of caution wording. This records needed materials; no new research was executed." }, { "item_id": "N35", "question_type": "Evidence condition", "question": "Does the raw ginger-powder capsule sheet preserve the original Korean/English text, C50, axes, corrections and empty/unverified value types?", "needed": "The complete current original and source identity, Korean/English text and axes, evidence/bibliography, corrections and typed equality of original empty values.", "role": "Required", "role_reason": "Track that conversion into formulation-specific sheets does not newly modify the original verdict, English placeholder correction or historical grade.", "application_exception": "The correction describes specific replacement of 2 fields, while generic wording remains in the current English evidence table. Preserve both without reading them as actual denominator, funding or CI verification.", "criterion": "Preserve the complete current original with its types. Do not automatically inherit generic English wording, original corrections, scores or axes as evidence of new verification or a new verdict.", "basis": "Existing method principles distinguish population, formulation, dose, timing, endpoint, comparison, denominators, overlap, support and harms in the retained reports. Detailed conditions are Chamgap's own application.", "condition_origin": "These are Chamgap in-house conditions developed with knowledge of the retained record for raw ginger powder, healthy adults, pain after eccentric exercise and matching placebo. They do not establish blinding, clinical-trial preregistration, official-tool certification, new independent clinical validation or a new formulation-specific grade.", "proposed_research": "Material needed: The complete current original and source identity, Korean/English text and axes, evidence/bibliography, corrections and typed equality of original empty values. This records needed materials; no new research was executed." }, { "item_id": "N36", "question_type": "Evidence condition", "question": "Is the raw ginger-powder capsule pain result at 24 hours combined with 48/72-hour pain, strength, ROM or CK?", "needed": "Original tables of time-specific pain, strength/ROM/CK and inflammatory-marker definitions, prospective hierarchy, denominators, analysis and CI.", "role": "Required", "role_reason": "A favorable 24-hour value must not make every other endpoint successful or turn separate handling into a statement of failure.", "application_exception": "Other endpoints are retained with separate scope. The original explanation/scope note says to treat them separately; it does not explicitly report each result as 0 or nonsignificant.", "criterion": "Keep selected 24-hour pain distinct from other times, functions and markers. Do not create individual values or determinate success/failure results not supplied by the original record.", "basis": "Existing method principles distinguish population, formulation, dose, timing, endpoint, comparison, denominators, overlap, support and harms in the retained reports. Detailed conditions are Chamgap's own application.", "condition_origin": "These are Chamgap in-house conditions developed with knowledge of the retained record for raw ginger powder, healthy adults, pain after eccentric exercise and matching placebo. They do not establish blinding, clinical-trial preregistration, official-tool certification, new independent clinical validation or a new formulation-specific grade.", "proposed_research": "Material needed: Original tables of time-specific pain, strength/ROM/CK and inflammatory-marker definitions, prospective hierarchy, denominators, analysis and CI. This records needed materials; no new research was executed." } ] }