{ "schema_version": "chamgap-public-evidence-check-1.0", "public_id": "v3014-s1", "verdict_number": "3014", "title": "Supervised Nordic walking with poles × Added pole-specific benefit over ordinary walking", "view_version": "1.0", "view_created_date": "2026-10-21", "criteria_version": "1.0", "criteria_date": "2026-10-06", "review_date": null, "legacy_evidence_date": "2026-09-07", "review_scope": { "materials_read": "Existing review summaries and stored records of methodological application", "clinical_papers_directly_read": false, "new_clinical_search": false, "limitation": "Existing stored summary and preserved methodology application records. External papers, abstracts, registration, protocols, SAPs, original result tables and support disclosures are unread, and review of existing content remains incomplete.", "date_meaning": "This is the date the stored materials were checked, not the date of a new search of the clinical literature." }, "claim_context": { "population": "The question concerns ordinary-walking comparisons in mild-to-moderate Parkinson's disease. Trial-specific eligibility, stage, medication state, freezing, orthostatic hypotension and comorbidities remain unverified.", "intervention": "The intervention is supervised Nordic-walking training with poles. Exercise participation, walking, instruction and supervision are distinguished from the added effect of the pole component alone.", "dose": "Session duration, frequency, intensity, pole fitting, instruction and actual participation remain unverified. Matching of exercise dose, instruction and contact with ordinary walking is not filled in as established.", "comparator": "The selected comparator is ordinary walking. Results from other standard-rehabilitation, treadmill, flexibility and relaxation programs are not converted into the same added-pole-effect comparison.", "endpoint": "The selected original result is UPDRS group-by-time P=.352 with no superiority over ordinary walking. Exact UPDRS scale scope, between-group effects, CIs and denominators remain unverified; standard-rehabilitation UPDRS-III is not transferred.", "duration": "The core direct comparison involved 33 participants over 8 weeks; the original citation's 32 completers are retained separately. Reuter's 90 participants over 6 months and standard rehabilitation's 40 participants over 6 weeks are different comparisons; post-training durability is a separate question.", "excluded_extensions": [ "Converting within-group improvement or exercise participation into an added between-group effect of poles alone", "Converting signals against standard rehabilitation, treadmill or other controls into the same ordinary-walking comparison", "Converting lack of superiority or a null group-by-time result into exact effect 0, equivalence or noninferiority", "Promoting an all-null bibliographic narrative into exact endpoint values, CIs or reading of complete original tables", "Extending limited functional results into recovery, fall prevention, durability or safety for every patient", "Adding shared reports, sheets or total samples into new unique trial, participant or independent-replication counts" ] }, "requirements": [ { "item_id": "N01", "question_type": "Evidence condition", "question": "Which added pole effect does this item concern?", "needed": "Existing pole question versus ordinary walking", "role": "Required", "role_reason": "Material on Existing pole question versus ordinary walking is needed to connect the selected added-pole-effect question with population, walking controls, training dose, endpoints, time points, denominators, precision and harm boundaries.", "application_exception": "Selected pole C and absent individual score, status and axes are retained, distinguishing parent C54, separate program C and fall-and-durability D. Within-group improvement or standard-rehabilitation signals are not converted into added pole benefit; null results are not promoted into exact effect 0, equivalence or noninferiority. No new effects, CIs, denominators, totals, grades or individual-care guidance are created.", "criterion": "Original material on Existing pole question versus ordinary walking must link to the same ordinary-walking control, pole component, endpoint, time point and denominators, distinguishing standard-rehabilitation programs, other controls, parent context and unread external material.", "basis": "Preserved principles distinguishing questions, direct comparisons, reports and trials, endpoints, denominators, precision and harms informed production.", "condition_origin": "These are evidence conditions for the existing added-pole-effect question versus ordinary walking. They do not establish preregistration, execution of an official tool or completed clinical content review.", "proposed_research": "Material needed: Materials separating the pole component with walking controls matched for time, intensity and instruction are needed. No new score or independence certification is created. This records needed materials; no new research was executed.", "current_reports": [ "R03" ], "existence": "Displayed selected and parent records exist in the stored summary. External availability, acquisition, content and reading of detailed materials remain separately unverified.", "acquired_read": "Complete stored parent Korean and English summary, selected question and bibliography read; external abstracts, full text, registration, protocols and analysis plans unread", "observation": "The selected question concerns added benefit from poles over ordinary walking. The original subclaim records a lower rating within C because the direct group-by-time result was null.", "condition_status": "Partly verified", "status_reason": "This state links partial information and gaps in the preserved selected and parent accounts. External verification and clinical content review remain incomplete; it does not certify fulfilled conditions, efficacy, safety, prespecification or independence.", "missingness": "Materials separating the pole component with walking controls matched for time, intensity and instruction are needed. No new score or independence certification is created.", "uncertainty": "Target effects, endpoint-specific denominators, measurement, prespecified hierarchy, bias, externally validated important differences, durability, harms, independence and overlap remain unverified. Original numbers, historical verification narratives and registration identifiers are not promoted into new calculations, completed content review or clinical certification.", "review_date": null, "reading_status": "Full text not read · Stored summary read", "additional_material": "Materials separating the pole component with walking controls matched for time, intensity and instruction are needed. No new score or independence certification is created." }, { "item_id": "N02", "question_type": "Evidence condition", "question": "Which trial directly compared ordinary walking?", "needed": "Monteiro's direct ordinary-walking control", "role": "Required", "role_reason": "Material on Monteiro's direct ordinary-walking control is needed to connect the selected added-pole-effect question with population, walking controls, training dose, endpoints, time points, denominators, precision and harm boundaries.", "application_exception": "Selected pole C and absent individual score, status and axes are retained, distinguishing parent C54, separate program C and fall-and-durability D. Within-group improvement or standard-rehabilitation signals are not converted into added pole benefit; null results are not promoted into exact effect 0, equivalence or noninferiority. No new effects, CIs, denominators, totals, grades or individual-care guidance are created.", "criterion": "Original material on Monteiro's direct ordinary-walking control must link to the same ordinary-walking control, pole component, endpoint, time point and denominators, distinguishing standard-rehabilitation programs, other controls, parent context and unread external material.", "basis": "Preserved principles distinguishing questions, direct comparisons, reports and trials, endpoints, denominators, precision and harms informed production.", "condition_origin": "These are evidence conditions for the existing added-pole-effect question versus ordinary walking. They do not establish preregistration, execution of an official tool or completed clinical content review.", "proposed_research": "Material needed: Group sessions, intensity, instruction and contact time, assessor masking, and allocation and analysis denominators are needed. This records needed materials; no new research was executed.", "current_reports": [ "R03" ], "existence": "Displayed selected and parent records exist in the stored summary. External availability, acquisition, content and reading of detailed materials remain separately unverified.", "acquired_read": "Complete stored parent Korean and English summary, selected question and bibliography read; external abstracts, full text, registration, protocols and analysis plans unread", "observation": "Monteiro 2021 was a single-blind randomized Nordic-walking versus walking trial with 33 participants over 8 weeks. Other exercise controls are not converted into the same comparison.", "condition_status": "Partly verified", "status_reason": "This state links partial information and gaps in the preserved selected and parent accounts. External verification and clinical content review remain incomplete; it does not certify fulfilled conditions, efficacy, safety, prespecification or independence.", "missingness": "Group sessions, intensity, instruction and contact time, assessor masking, and allocation and analysis denominators are needed.", "uncertainty": "Target effects, endpoint-specific denominators, measurement, prespecified hierarchy, bias, externally validated important differences, durability, harms, independence and overlap remain unverified. Original numbers, historical verification narratives and registration identifiers are not promoted into new calculations, completed content review or clinical certification.", "review_date": null, "reading_status": "Full text not read · Stored summary read", "additional_material": "Group sessions, intensity, instruction and contact time, assessor masking, and allocation and analysis denominators are needed." }, { "item_id": "N03", "question_type": "Evidence condition", "question": "What is the null UPDRS group-by-time result?", "needed": "Direct group comparison and the original null narrative", "role": "Required", "role_reason": "Material on Direct group comparison and the original null narrative is needed to connect the selected added-pole-effect question with population, walking controls, training dose, endpoints, time points, denominators, precision and harm boundaries.", "application_exception": "Selected pole C and absent individual score, status and axes are retained, distinguishing parent C54, separate program C and fall-and-durability D. Within-group improvement or standard-rehabilitation signals are not converted into added pole benefit; null results are not promoted into exact effect 0, equivalence or noninferiority. No new effects, CIs, denominators, totals, grades or individual-care guidance are created.", "criterion": "Original material on Direct group comparison and the original null narrative must link to the same ordinary-walking control, pole component, endpoint, time point and denominators, distinguishing standard-rehabilitation programs, other controls, parent context and unread external material.", "basis": "Preserved principles distinguishing questions, direct comparisons, reports and trials, endpoints, denominators, precision and harms informed production.", "condition_origin": "These are evidence conditions for the existing added-pole-effect question versus ordinary walking. They do not establish preregistration, execution of an official tool or completed clinical content review.", "proposed_research": "Material needed: The model, exact UPDRS scale scope, between-group effects and CIs, time points and denominators are needed. A P value alone does not establish exact effect 0 or precise equivalence. This records needed materials; no new research was executed.", "current_reports": [ "R03" ], "existence": "Displayed selected and parent records exist in the stored summary. External availability, acquisition, content and reading of detailed materials remain separately unverified.", "acquired_read": "Complete stored parent Korean and English summary, selected question and bibliography read; external abstracts, full text, registration, protocols and analysis plans unread", "observation": "The original UPDRS group-by-time P=.352 and lack of superiority over ordinary walking are retained. They are distinguished from UPDRS-III P=.047 versus standard rehabilitation.", "condition_status": "Partly verified", "status_reason": "This state links partial information and gaps in the preserved selected and parent accounts. External verification and clinical content review remain incomplete; it does not certify fulfilled conditions, efficacy, safety, prespecification or independence.", "missingness": "The model, exact UPDRS scale scope, between-group effects and CIs, time points and denominators are needed. A P value alone does not establish exact effect 0 or precise equivalence.", "uncertainty": "Target effects, endpoint-specific denominators, measurement, prespecified hierarchy, bias, externally validated important differences, durability, harms, independence and overlap remain unverified. Original numbers, historical verification narratives and registration identifiers are not promoted into new calculations, completed content review or clinical certification.", "review_date": null, "reading_status": "Full text not read · Stored summary read", "additional_material": "The model, exact UPDRS scale scope, between-group effects and CIs, time points and denominators are needed. A P value alone does not establish exact effect 0 or precise equivalence." }, { "item_id": "N04", "question_type": "Evidence condition", "question": "Does lack of superiority establish equivalence or noninferiority?", "needed": "Superiority testing versus other designs", "role": "Required", "role_reason": "Material on Superiority testing versus other designs is needed to connect the selected added-pole-effect question with population, walking controls, training dose, endpoints, time points, denominators, precision and harm boundaries.", "application_exception": "Selected pole C and absent individual score, status and axes are retained, distinguishing parent C54, separate program C and fall-and-durability D. Within-group improvement or standard-rehabilitation signals are not converted into added pole benefit; null results are not promoted into exact effect 0, equivalence or noninferiority. No new effects, CIs, denominators, totals, grades or individual-care guidance are created.", "criterion": "Original material on Superiority testing versus other designs must link to the same ordinary-walking control, pole component, endpoint, time point and denominators, distinguishing standard-rehabilitation programs, other controls, parent context and unread external material.", "basis": "Preserved principles distinguishing questions, direct comparisons, reports and trials, endpoints, denominators, precision and harms informed production.", "condition_origin": "These are evidence conditions for the existing added-pole-effect question versus ordinary walking. They do not establish preregistration, execution of an official tool or completed clinical content review.", "proposed_research": "Material needed: Prespecified target effects, analysis plans, margins and corresponding CIs are needed. A nonsignificant superiority test is not converted into an equivalence judgment. This records needed materials; no new research was executed.", "current_reports": [ "R03" ], "existence": "Displayed selected and parent records exist in the stored summary. External availability, acquisition, content and reading of detailed materials remain separately unverified.", "acquired_read": "Complete stored parent Korean and English summary, selected question and bibliography read; external abstracts, full text, registration, protocols and analysis plans unread", "observation": "Lack of superiority is the original trial result. The stored summary lacks prespecified equivalence or noninferiority margins and corresponding CIs, so equivalence between the exercises is not newly judged.", "condition_status": "Partly verified", "status_reason": "This state links partial information and gaps in the preserved selected and parent accounts. External verification and clinical content review remain incomplete; it does not certify fulfilled conditions, efficacy, safety, prespecification or independence.", "missingness": "Prespecified target effects, analysis plans, margins and corresponding CIs are needed. A nonsignificant superiority test is not converted into an equivalence judgment.", "uncertainty": "Target effects, endpoint-specific denominators, measurement, prespecified hierarchy, bias, externally validated important differences, durability, harms, independence and overlap remain unverified. Original numbers, historical verification narratives and registration identifiers are not promoted into new calculations, completed content review or clinical certification.", "review_date": null, "reading_status": "Full text not read · Stored summary read", "additional_material": "Prespecified target effects, analysis plans, margins and corresponding CIs are needed. A nonsignificant superiority test is not converted into an equivalence judgment." }, { "item_id": "N05", "question_type": "Evidence condition", "question": "How do allocated and completed samples differ?", "needed": "Group allocation, completion and endpoint analysis populations", "role": "Required", "role_reason": "Material on Group allocation, completion and endpoint analysis populations is needed to connect the selected added-pole-effect question with population, walking controls, training dose, endpoints, time points, denominators, precision and harm boundaries.", "application_exception": "Selected pole C and absent individual score, status and axes are retained, distinguishing parent C54, separate program C and fall-and-durability D. Within-group improvement or standard-rehabilitation signals are not converted into added pole benefit; null results are not promoted into exact effect 0, equivalence or noninferiority. No new effects, CIs, denominators, totals, grades or individual-care guidance are created.", "criterion": "Original material on Group allocation, completion and endpoint analysis populations must link to the same ordinary-walking control, pole component, endpoint, time point and denominators, distinguishing standard-rehabilitation programs, other controls, parent context and unread external material.", "basis": "Preserved principles distinguishing questions, direct comparisons, reports and trials, endpoints, denominators, precision and harms informed production.", "condition_origin": "These are evidence conditions for the existing added-pole-effect question versus ordinary walking. They do not establish preregistration, execution of an official tool or completed clinical content review.", "proposed_research": "Material needed: Allocation, completion, measurement and analysis tables, withdrawal and missing-data handling, and ITT definitions are needed. Differences are not newly calculated, and completers are not used as every endpoint's denominator. This records needed materials; no new research was executed.", "current_reports": [ "R03" ], "existence": "Displayed selected and parent records exist in the stored summary. External availability, acquisition, content and reading of detailed materials remain separately unverified.", "acquired_read": "Complete stored parent Korean and English summary, selected question and bibliography read; external abstracts, full text, registration, protocols and analysis plans unread", "observation": "The original evidence's 33 participants and the citation's 32 completers are retained separately. Group-specific and UPDRS analysis denominators and missingness reasons remain unverified.", "condition_status": "Partly verified", "status_reason": "This state links partial information and gaps in the preserved selected and parent accounts. External verification and clinical content review remain incomplete; it does not certify fulfilled conditions, efficacy, safety, prespecification or independence.", "missingness": "Allocation, completion, measurement and analysis tables, withdrawal and missing-data handling, and ITT definitions are needed. Differences are not newly calculated, and completers are not used as every endpoint's denominator.", "uncertainty": "Target effects, endpoint-specific denominators, measurement, prespecified hierarchy, bias, externally validated important differences, durability, harms, independence and overlap remain unverified. Original numbers, historical verification narratives and registration identifiers are not promoted into new calculations, completed content review or clinical certification.", "review_date": null, "reading_status": "Full text not read · Stored summary read", "additional_material": "Allocation, completion, measurement and analysis tables, withdrawal and missing-data handling, and ITT definitions are needed. Differences are not newly calculated, and completers are not used as every endpoint's denominator." }, { "item_id": "N06", "question_type": "Evidence condition", "question": "How far is the summary of all-null results verified?", "needed": "Bibliographic summary versus endpoint-specific original tables", "role": "Required", "role_reason": "Material on Bibliographic summary versus endpoint-specific original tables is needed to connect the selected added-pole-effect question with population, walking controls, training dose, endpoints, time points, denominators, precision and harm boundaries.", "application_exception": "Selected pole C and absent individual score, status and axes are retained, distinguishing parent C54, separate program C and fall-and-durability D. Within-group improvement or standard-rehabilitation signals are not converted into added pole benefit; null results are not promoted into exact effect 0, equivalence or noninferiority. No new effects, CIs, denominators, totals, grades or individual-care guidance are created.", "criterion": "Original material on Bibliographic summary versus endpoint-specific original tables must link to the same ordinary-walking control, pole component, endpoint, time point and denominators, distinguishing standard-rehabilitation programs, other controls, parent context and unread external material.", "basis": "Preserved principles distinguishing questions, direct comparisons, reports and trials, endpoints, denominators, precision and harms informed production.", "condition_origin": "These are evidence conditions for the existing added-pole-effect question versus ordinary walking. They do not establish preregistration, execution of an official tool or completed clinical content review.", "proposed_research": "Material needed: Between-group effects and CIs, denominators and prespecified hierarchy for all endpoints and time points are needed. A single P value is not copied as the exact result for other endpoints. This records needed materials; no new research was executed.", "current_reports": [ "R03" ], "existence": "Displayed selected and parent records exist in the stored summary. External availability, acquisition, content and reading of detailed materials remain separately unverified.", "acquired_read": "Complete stored parent Korean and English summary, selected question and bibliography read; external abstracts, full text, registration, protocols and analysis plans unread", "observation": "The original citation describes null results across outcomes versus ordinary walking over 8 weeks; the evidence lists motor, functional, gait and quality-of-life outcomes. Complete original endpoint tables were not read or verified in this work.", "condition_status": "Partly verified", "status_reason": "This state links partial information and gaps in the preserved selected and parent accounts. External verification and clinical content review remain incomplete; it does not certify fulfilled conditions, efficacy, safety, prespecification or independence.", "missingness": "Between-group effects and CIs, denominators and prespecified hierarchy for all endpoints and time points are needed. A single P value is not copied as the exact result for other endpoints.", "uncertainty": "Target effects, endpoint-specific denominators, measurement, prespecified hierarchy, bias, externally validated important differences, durability, harms, independence and overlap remain unverified. Original numbers, historical verification narratives and registration identifiers are not promoted into new calculations, completed content review or clinical certification.", "review_date": null, "reading_status": "Full text not read · Stored summary read", "additional_material": "Between-group effects and CIs, denominators and prespecified hierarchy for all endpoints and time points are needed. A single P value is not copied as the exact result for other endpoints." }, { "item_id": "N07", "question_type": "Evidence condition", "question": "Is improvement within Nordic walking a pole-specific effect?", "needed": "Exercise participation, within-group improvement and added group effects", "role": "Required", "role_reason": "Material on Exercise participation, within-group improvement and added group effects is needed to connect the selected added-pole-effect question with population, walking controls, training dose, endpoints, time points, denominators, precision and harm boundaries.", "application_exception": "Selected pole C and absent individual score, status and axes are retained, distinguishing parent C54, separate program C and fall-and-durability D. Within-group improvement or standard-rehabilitation signals are not converted into added pole benefit; null results are not promoted into exact effect 0, equivalence or noninferiority. No new effects, CIs, denominators, totals, grades or individual-care guidance are created.", "criterion": "Original material on Exercise participation, within-group improvement and added group effects must link to the same ordinary-walking control, pole component, endpoint, time point and denominators, distinguishing standard-rehabilitation programs, other controls, parent context and unread external material.", "basis": "Preserved principles distinguishing questions, direct comparisons, reports and trials, endpoints, denominators, precision and harms informed production.", "condition_origin": "These are evidence conditions for the existing added-pole-effect question versus ordinary walking. They do not establish preregistration, execution of an official tool or completed clinical content review.", "proposed_research": "Material needed: Between-group target effects, change models, exercise dose, attendance and common instruction are needed. Differences in within-group change are not calculated as new direct effect estimates. This records needed materials; no new research was executed.", "current_reports": [ "R03" ], "existence": "Displayed selected and parent records exist in the stored summary. External availability, acquisition, content and reading of detailed materials remain separately unverified.", "acquired_read": "Complete stored parent Korean and English summary, selected question and bibliography read; external abstracts, full text, registration, protocols and analysis plans unread", "observation": "The original explanation states that ordinary walking can also improve outcomes and that Nordic-group improvement alone does not establish superiority over equal-duration walking.", "condition_status": "Partly verified", "status_reason": "This state links partial information and gaps in the preserved selected and parent accounts. External verification and clinical content review remain incomplete; it does not certify fulfilled conditions, efficacy, safety, prespecification or independence.", "missingness": "Between-group target effects, change models, exercise dose, attendance and common instruction are needed. Differences in within-group change are not calculated as new direct effect estimates.", "uncertainty": "Target effects, endpoint-specific denominators, measurement, prespecified hierarchy, bias, externally validated important differences, durability, harms, independence and overlap remain unverified. Original numbers, historical verification narratives and registration identifiers are not promoted into new calculations, completed content review or clinical certification.", "review_date": null, "reading_status": "Full text not read · Stored summary read", "additional_material": "Between-group target effects, change models, exercise dose, attendance and common instruction are needed. Differences in within-group change are not calculated as new direct effect estimates." }, { "item_id": "N08", "question_type": "Evidence condition", "question": "What context do Reuter's selected-measure signals provide?", "needed": "Actual contrasts by ordinary-walking and flexibility control", "role": "Required", "role_reason": "Material on Actual contrasts by ordinary-walking and flexibility control is needed to connect the selected added-pole-effect question with population, walking controls, training dose, endpoints, time points, denominators, precision and harm boundaries.", "application_exception": "Selected pole C and absent individual score, status and axes are retained, distinguishing parent C54, separate program C and fall-and-durability D. Within-group improvement or standard-rehabilitation signals are not converted into added pole benefit; null results are not promoted into exact effect 0, equivalence or noninferiority. No new effects, CIs, denominators, totals, grades or individual-care guidance are created.", "criterion": "Original material on Actual contrasts by ordinary-walking and flexibility control must link to the same ordinary-walking control, pole component, endpoint, time point and denominators, distinguishing standard-rehabilitation programs, other controls, parent context and unread external material.", "basis": "Preserved principles distinguishing questions, direct comparisons, reports and trials, endpoints, denominators, precision and harms informed production.", "condition_origin": "These are evidence conditions for the existing added-pole-effect question versus ordinary walking. They do not establish preregistration, execution of an official tool or completed clinical content review.", "proposed_research": "Material needed: All measures, denominators, effects and CIs, hierarchy and multiplicity materials by comparator are needed. Selected measures are not expanded into all pole effects. This records needed materials; no new research was executed.", "current_reports": [ "R01", "R03" ], "existence": "Displayed selected and parent records exist in the stored summary. External availability, acquisition, content and reading of detailed materials remain separately unverified.", "acquired_read": "Complete stored parent Korean and English summary, selected question and bibliography read; external abstracts, full text, registration, protocols and analysis plans unread", "observation": "Reuter was a 90-person, 3-arm, 6-month trial with summarized superiority on selected posture, stride and variability measures. Exact comparator-specific contrasts, time points, values and CIs are unlinked.", "condition_status": "Partly verified", "status_reason": "This state links partial information and gaps in the preserved selected and parent accounts. External verification and clinical content review remain incomplete; it does not certify fulfilled conditions, efficacy, safety, prespecification or independence.", "missingness": "All measures, denominators, effects and CIs, hierarchy and multiplicity materials by comparator are needed. Selected measures are not expanded into all pole effects.", "uncertainty": "Target effects, endpoint-specific denominators, measurement, prespecified hierarchy, bias, externally validated important differences, durability, harms, independence and overlap remain unverified. Original numbers, historical verification narratives and registration identifiers are not promoted into new calculations, completed content review or clinical certification.", "review_date": null, "reading_status": "Full text not read · Stored summary read", "additional_material": "All measures, denominators, effects and CIs, hierarchy and multiplicity materials by comparator are needed. Selected measures are not expanded into all pole effects." }, { "item_id": "N09", "question_type": "Evidence condition", "question": "Is the standard-rehabilitation signal the same added pole effect?", "needed": "Whole-program results against another control", "role": "Required", "role_reason": "Material on Whole-program results against another control is needed to connect the selected added-pole-effect question with population, walking controls, training dose, endpoints, time points, denominators, precision and harm boundaries.", "application_exception": "Selected pole C and absent individual score, status and axes are retained, distinguishing parent C54, separate program C and fall-and-durability D. Within-group improvement or standard-rehabilitation signals are not converted into added pole benefit; null results are not promoted into exact effect 0, equivalence or noninferiority. No new effects, CIs, denominators, totals, grades or individual-care guidance are created.", "criterion": "Original material on Whole-program results against another control must link to the same ordinary-walking control, pole component, endpoint, time point and denominators, distinguishing standard-rehabilitation programs, other controls, parent context and unread external material.", "basis": "Preserved principles distinguishing questions, direct comparisons, reports and trials, endpoints, denominators, precision and harms informed production.", "condition_origin": "These are evidence conditions for the existing added-pole-effect question versus ordinary walking. They do not establish preregistration, execution of an official tool or completed clinical content review.", "proposed_research": "Material needed: Standard-rehabilitation content, non-pole exercise and instruction differences, and direct comparisons against the same ordinary walking are needed. This records needed materials; no new research was executed.", "current_reports": [ "R03", "R04" ], "existence": "Displayed selected and parent records exist in the stored summary. External availability, acquisition, content and reading of detailed materials remain separately unverified.", "acquired_read": "Complete stored parent Korean and English summary, selected question and bibliography read; external abstracts, full text, registration, protocols and analysis plans unread", "observation": "Median UPDRS-III reductions of 8.5 versus 6.0, P=.047 and null DGI P=.064 in the 40-person, 6-week standard-rehabilitation comparison are retained separately. They are not the same evidence for added pole benefit over ordinary walking.", "condition_status": "Partly verified", "status_reason": "This state links partial information and gaps in the preserved selected and parent accounts. External verification and clinical content review remain incomplete; it does not certify fulfilled conditions, efficacy, safety, prespecification or independence.", "missingness": "Standard-rehabilitation content, non-pole exercise and instruction differences, and direct comparisons against the same ordinary walking are needed.", "uncertainty": "Target effects, endpoint-specific denominators, measurement, prespecified hierarchy, bias, externally validated important differences, durability, harms, independence and overlap remain unverified. Original numbers, historical verification narratives and registration identifiers are not promoted into new calculations, completed content review or clinical certification.", "review_date": null, "reading_status": "Full text not read · Stored summary read", "additional_material": "Standard-rehabilitation content, non-pole exercise and instruction differences, and direct comparisons against the same ordinary walking are needed." }, { "item_id": "N10", "question_type": "Evidence condition", "question": "Does the treadmill pilot isolate poles alone?", "needed": "Directness limits of another active control", "role": "Required", "role_reason": "Material on Directness limits of another active control is needed to connect the selected added-pole-effect question with population, walking controls, training dose, endpoints, time points, denominators, precision and harm boundaries.", "application_exception": "Selected pole C and absent individual score, status and axes are retained, distinguishing parent C54, separate program C and fall-and-durability D. Within-group improvement or standard-rehabilitation signals are not converted into added pole benefit; null results are not promoted into exact effect 0, equivalence or noninferiority. No new effects, CIs, denominators, totals, grades or individual-care guidance are created.", "criterion": "Original material on Directness limits of another active control must link to the same ordinary-walking control, pole component, endpoint, time point and denominators, distinguishing standard-rehabilitation programs, other controls, parent context and unread external material.", "basis": "Preserved principles distinguishing questions, direct comparisons, reports and trials, endpoints, denominators, precision and harms informed production.", "condition_origin": "These are evidence conditions for the existing added-pole-effect question versus ordinary walking. They do not establish preregistration, execution of an official tool or completed clinical content review.", "proposed_research": "Material needed: Program details, control exercise dose and instruction, denominators, endpoints, effects and CIs, and recruitment identifiers are needed. This records needed materials; no new research was executed.", "current_reports": [ "R02", "R03" ], "existence": "Displayed selected and parent records exist in the stored summary. External availability, acquisition, content and reading of detailed materials remain separately unverified.", "acquired_read": "Complete stored parent Korean and English summary, selected question and bibliography read; external abstracts, full text, registration, protocols and analysis plans unread", "observation": "Cugusi's citation-only 20-person treadmill pilot and functional signals are retained. There is no separate original evidence entry or exact effect, and isolation of poles alone remains unverified.", "condition_status": "Partly verified", "status_reason": "This state links partial information and gaps in the preserved selected and parent accounts. External verification and clinical content review remain incomplete; it does not certify fulfilled conditions, efficacy, safety, prespecification or independence.", "missingness": "Program details, control exercise dose and instruction, denominators, endpoints, effects and CIs, and recruitment identifiers are needed.", "uncertainty": "Target effects, endpoint-specific denominators, measurement, prespecified hierarchy, bias, externally validated important differences, durability, harms, independence and overlap remain unverified. Original numbers, historical verification narratives and registration identifiers are not promoted into new calculations, completed content review or clinical certification.", "review_date": null, "reading_status": "Full text not read · Stored summary read", "additional_material": "Program details, control exercise dose and instruction, denominators, endpoints, effects and CIs, and recruitment identifiers are needed." }, { "item_id": "N11", "question_type": "Evidence condition", "question": "Are different trial results combined as consistent replication?", "needed": "Differences in duration, controls, endpoints and training", "role": "Required", "role_reason": "Material on Differences in duration, controls, endpoints and training is needed to connect the selected added-pole-effect question with population, walking controls, training dose, endpoints, time points, denominators, precision and harm boundaries.", "application_exception": "Selected pole C and absent individual score, status and axes are retained, distinguishing parent C54, separate program C and fall-and-durability D. Within-group improvement or standard-rehabilitation signals are not converted into added pole benefit; null results are not promoted into exact effect 0, equivalence or noninferiority. No new effects, CIs, denominators, totals, grades or individual-care guidance are created.", "criterion": "Original material on Differences in duration, controls, endpoints and training must link to the same ordinary-walking control, pole component, endpoint, time point and denominators, distinguishing standard-rehabilitation programs, other controls, parent context and unread external material.", "basis": "Preserved principles distinguishing questions, direct comparisons, reports and trials, endpoints, denominators, precision and harms informed production.", "condition_origin": "These are evidence conditions for the existing added-pole-effect question versus ordinary walking. They do not establish preregistration, execution of an official tool or completed clinical content review.", "proposed_research": "Material needed: Walking controls with matched exercise dose, replication of prespecified primary endpoints, trial-specific controls, and original effects and CIs are needed. Unique trial and participant totals remain unverified. This records needed materials; no new research was executed.", "current_reports": [ "R01", "R02", "R03", "R04" ], "existence": "Displayed selected and parent records exist in the stored summary. External availability, acquisition, content and reading of detailed materials remain separately unverified.", "acquired_read": "Complete stored parent Korean and English summary, selected question and bibliography read; external abstracts, full text, registration, protocols and analysis plans unread", "observation": "The parent records variation in added pole benefit across trials. Selected-measure signals, a null direct walking comparison and other active controls are not combined as the same independent replication.", "condition_status": "Partly verified", "status_reason": "This state links partial information and gaps in the preserved selected and parent accounts. External verification and clinical content review remain incomplete; it does not certify fulfilled conditions, efficacy, safety, prespecification or independence.", "missingness": "Walking controls with matched exercise dose, replication of prespecified primary endpoints, trial-specific controls, and original effects and CIs are needed. Unique trial and participant totals remain unverified.", "uncertainty": "Target effects, endpoint-specific denominators, measurement, prespecified hierarchy, bias, externally validated important differences, durability, harms, independence and overlap remain unverified. Original numbers, historical verification narratives and registration identifiers are not promoted into new calculations, completed content review or clinical certification.", "review_date": null, "reading_status": "Full text not read · Stored summary read", "additional_material": "Walking controls with matched exercise dose, replication of prespecified primary endpoints, trial-specific controls, and original effects and CIs are needed. Unique trial and participant totals remain unverified." }, { "item_id": "N12", "question_type": "Evidence condition", "question": "Do public funding and supplied poles verify independence?", "needed": "Funding, supplier, affiliation, design and analysis roles", "role": "Required", "role_reason": "Material on Funding, supplier, affiliation, design and analysis roles is needed to connect the selected added-pole-effect question with population, walking controls, training dose, endpoints, time points, denominators, precision and harm boundaries.", "application_exception": "Selected pole C and absent individual score, status and axes are retained, distinguishing parent C54, separate program C and fall-and-durability D. Within-group improvement or standard-rehabilitation signals are not converted into added pole benefit; null results are not promoted into exact effect 0, equivalence or noninferiority. No new effects, CIs, denominators, totals, grades or individual-care guidance are created.", "criterion": "Original material on Funding, supplier, affiliation, design and analysis roles must link to the same ordinary-walking control, pole component, endpoint, time point and denominators, distinguishing standard-rehabilitation programs, other controls, parent context and unread external material.", "basis": "Preserved principles distinguishing questions, direct comparisons, reports and trials, endpoints, denominators, precision and harms informed production.", "condition_origin": "These are evidence conditions for the existing added-pole-effect question versus ordinary walking. They do not establish preregistration, execution of an official tool or completed clinical content review.", "proposed_research": "Material needed: Disclosures on poles, financial support, company and author relationships, and design, analysis and publication involvement are needed. Unverified items are not labeled absent. This records needed materials; no new research was executed.", "current_reports": [ "R03" ], "existence": "Displayed selected and parent records exist in the stored summary. External availability, acquisition, content and reading of detailed materials remain separately unverified.", "acquired_read": "Complete stored parent Korean and English summary, selected question and bibliography read; external abstracts, full text, registration, protocols and analysis plans unread", "observation": "The direct walking comparison records public funding and supplied poles. Supplier identity and roles, author relationships and analysis involvement remain unverified in the summary.", "condition_status": "Partly verified", "status_reason": "This state links partial information and gaps in the preserved selected and parent accounts. External verification and clinical content review remain incomplete; it does not certify fulfilled conditions, efficacy, safety, prespecification or independence.", "missingness": "Disclosures on poles, financial support, company and author relationships, and design, analysis and publication involvement are needed. Unverified items are not labeled absent.", "uncertainty": "Target effects, endpoint-specific denominators, measurement, prespecified hierarchy, bias, externally validated important differences, durability, harms, independence and overlap remain unverified. Original numbers, historical verification narratives and registration identifiers are not promoted into new calculations, completed content review or clinical certification.", "review_date": null, "reading_status": "Full text not read · Stored summary read", "additional_material": "Disclosures on poles, financial support, company and author relationships, and design, analysis and publication involvement are needed. Unverified items are not labeled absent." }, { "item_id": "N13", "question_type": "Evidence condition", "question": "Do functional results also answer fall prevention and durability?", "needed": "Function, meaningful differences, falls and post-training follow-up", "role": "Required", "role_reason": "Material on Function, meaningful differences, falls and post-training follow-up is needed to connect the selected added-pole-effect question with population, walking controls, training dose, endpoints, time points, denominators, precision and harm boundaries.", "application_exception": "Selected pole C and absent individual score, status and axes are retained, distinguishing parent C54, separate program C and fall-and-durability D. Within-group improvement or standard-rehabilitation signals are not converted into added pole benefit; null results are not promoted into exact effect 0, equivalence or noninferiority. No new effects, CIs, denominators, totals, grades or individual-care guidance are created.", "criterion": "Original material on Function, meaningful differences, falls and post-training follow-up must link to the same ordinary-walking control, pole component, endpoint, time point and denominators, distinguishing standard-rehabilitation programs, other controls, parent context and unread external material.", "basis": "Preserved principles distinguishing questions, direct comparisons, reports and trials, endpoints, denominators, precision and harms informed production.", "condition_origin": "These are evidence conditions for the existing added-pole-effect question versus ordinary walking. They do not establish preregistration, execution of an official tool or completed clinical content review.", "proposed_research": "Material needed: CIs for direct functional effects, patient-important differences, separate fall events and exposure, and post-training follow-up are needed. Events are not calculated as new rates. This records needed materials; no new research was executed.", "current_reports": [ "R01", "R03" ], "existence": "Displayed selected and parent records exist in the stored summary. External availability, acquisition, content and reading of detailed materials remain separately unverified.", "acquired_read": "Complete stored parent Korean and English summary, selected question and bibliography read; external abstracts, full text, registration, protocols and analysis plans unread", "observation": "The original account describes weak added pole benefit over ordinary walking and incompletely established fall prevention and durability. Null functional results are not converted into a fall-prevention conclusion.", "condition_status": "Partly verified", "status_reason": "This state links partial information and gaps in the preserved selected and parent accounts. External verification and clinical content review remain incomplete; it does not certify fulfilled conditions, efficacy, safety, prespecification or independence.", "missingness": "CIs for direct functional effects, patient-important differences, separate fall events and exposure, and post-training follow-up are needed. Events are not calculated as new rates.", "uncertainty": "Target effects, endpoint-specific denominators, measurement, prespecified hierarchy, bias, externally validated important differences, durability, harms, independence and overlap remain unverified. Original numbers, historical verification narratives and registration identifiers are not promoted into new calculations, completed content review or clinical certification.", "review_date": null, "reading_status": "Full text not read · Stored summary read", "additional_material": "CIs for direct functional effects, patient-important differences, separate fall events and exposure, and post-training follow-up are needed. Events are not calculated as new rates." }, { "item_id": "N14", "question_type": "Evidence condition", "question": "Which patients does the question concern?", "needed": "Detailed eligibility in mild-to-moderate Parkinson's disease", "role": "Required", "role_reason": "Material on Detailed eligibility in mild-to-moderate Parkinson's disease is needed to connect the selected added-pole-effect question with population, walking controls, training dose, endpoints, time points, denominators, precision and harm boundaries.", "application_exception": "Selected pole C and absent individual score, status and axes are retained, distinguishing parent C54, separate program C and fall-and-durability D. Within-group improvement or standard-rehabilitation signals are not converted into added pole benefit; null results are not promoted into exact effect 0, equivalence or noninferiority. No new effects, CIs, denominators, totals, grades or individual-care guidance are created.", "criterion": "Original material on Detailed eligibility in mild-to-moderate Parkinson's disease must link to the same ordinary-walking control, pole component, endpoint, time point and denominators, distinguishing standard-rehabilitation programs, other controls, parent context and unread external material.", "basis": "Preserved principles distinguishing questions, direct comparisons, reports and trials, endpoints, denominators, precision and harms informed production.", "condition_origin": "These are evidence conditions for the existing added-pole-effect question versus ordinary walking. They do not establish preregistration, execution of an official tool or completed clinical content review.", "proposed_research": "Material needed: Trial-specific diagnosis, stage, medication state, freezing, orthostatic hypotension, comorbidities and exclusions are needed. The scope is not expanded to severe disease or other patients. This records needed materials; no new research was executed.", "current_reports": [ "R01", "R02", "R03", "R04" ], "existence": "Displayed selected and parent records exist in the stored summary. External availability, acquisition, content and reading of detailed materials remain separately unverified.", "acquired_read": "Complete stored parent Korean and English summary, selected question and bibliography read; external abstracts, full text, registration, protocols and analysis plans unread", "observation": "The parent Korean and English scope concerns mild-to-moderate Parkinson's disease. A representative trial's size and duration are not treated as eligibility criteria for all patients.", "condition_status": "Partly verified", "status_reason": "This state links partial information and gaps in the preserved selected and parent accounts. External verification and clinical content review remain incomplete; it does not certify fulfilled conditions, efficacy, safety, prespecification or independence.", "missingness": "Trial-specific diagnosis, stage, medication state, freezing, orthostatic hypotension, comorbidities and exclusions are needed. The scope is not expanded to severe disease or other patients.", "uncertainty": "Target effects, endpoint-specific denominators, measurement, prespecified hierarchy, bias, externally validated important differences, durability, harms, independence and overlap remain unverified. Original numbers, historical verification narratives and registration identifiers are not promoted into new calculations, completed content review or clinical certification.", "review_date": null, "reading_status": "Full text not read · Stored summary read", "additional_material": "Trial-specific diagnosis, stage, medication state, freezing, orthostatic hypotension, comorbidities and exclusions are needed. The scope is not expanded to severe disease or other patients." }, { "item_id": "N15", "question_type": "Evidence condition", "question": "Are actual training dose and supervision known?", "needed": "Sessions, frequency, intensity, pole fitting and adherence", "role": "Required", "role_reason": "Material on Sessions, frequency, intensity, pole fitting and adherence is needed to connect the selected added-pole-effect question with population, walking controls, training dose, endpoints, time points, denominators, precision and harm boundaries.", "application_exception": "Selected pole C and absent individual score, status and axes are retained, distinguishing parent C54, separate program C and fall-and-durability D. Within-group improvement or standard-rehabilitation signals are not converted into added pole benefit; null results are not promoted into exact effect 0, equivalence or noninferiority. No new effects, CIs, denominators, totals, grades or individual-care guidance are created.", "criterion": "Original material on Sessions, frequency, intensity, pole fitting and adherence must link to the same ordinary-walking control, pole component, endpoint, time point and denominators, distinguishing standard-rehabilitation programs, other controls, parent context and unread external material.", "basis": "Preserved principles distinguishing questions, direct comparisons, reports and trials, endpoints, denominators, precision and harms informed production.", "condition_origin": "These are evidence conditions for the existing added-pole-effect question versus ordinary walking. They do not establish preregistration, execution of an official tool or completed clinical content review.", "proposed_research": "Material needed: Trial-specific time, frequency, intensity, technique instruction, pole fitting, attendance and control exposure are needed. This records needed materials; no new research was executed.", "current_reports": [ "R01", "R02", "R03", "R04" ], "existence": "Displayed selected and parent records exist in the stored summary. External availability, acquisition, content and reading of detailed materials remain separately unverified.", "acquired_read": "Complete stored parent Korean and English summary, selected question and bibliography read; external abstracts, full text, registration, protocols and analysis plans unread", "observation": "The original intervention is supervised training with poles. A program name is not a numeric exercise dose; detailed sessions and actual participation remain unverified.", "condition_status": "Partly verified", "status_reason": "This state links partial information and gaps in the preserved selected and parent accounts. External verification and clinical content review remain incomplete; it does not certify fulfilled conditions, efficacy, safety, prespecification or independence.", "missingness": "Trial-specific time, frequency, intensity, technique instruction, pole fitting, attendance and control exposure are needed.", "uncertainty": "Target effects, endpoint-specific denominators, measurement, prespecified hierarchy, bias, externally validated important differences, durability, harms, independence and overlap remain unverified. Original numbers, historical verification narratives and registration identifiers are not promoted into new calculations, completed content review or clinical certification.", "review_date": null, "reading_status": "Full text not read · Stored summary read", "additional_material": "Trial-specific time, frequency, intensity, technique instruction, pole fitting, attendance and control exposure are needed." }, { "item_id": "N16", "question_type": "Evidence condition", "question": "Are all active exercise controls equivalent?", "needed": "Standard rehabilitation, walking, treadmill, flexibility and relaxation", "role": "Required", "role_reason": "Material on Standard rehabilitation, walking, treadmill, flexibility and relaxation is needed to connect the selected added-pole-effect question with population, walking controls, training dose, endpoints, time points, denominators, precision and harm boundaries.", "application_exception": "Selected pole C and absent individual score, status and axes are retained, distinguishing parent C54, separate program C and fall-and-durability D. Within-group improvement or standard-rehabilitation signals are not converted into added pole benefit; null results are not promoted into exact effect 0, equivalence or noninferiority. No new effects, CIs, denominators, totals, grades or individual-care guidance are created.", "criterion": "Original material on Standard rehabilitation, walking, treadmill, flexibility and relaxation must link to the same ordinary-walking control, pole component, endpoint, time point and denominators, distinguishing standard-rehabilitation programs, other controls, parent context and unread external material.", "basis": "Preserved principles distinguishing questions, direct comparisons, reports and trials, endpoints, denominators, precision and harms informed production.", "condition_origin": "These are evidence conditions for the existing added-pole-effect question versus ordinary walking. They do not establish preregistration, execution of an official tool or completed clinical content review.", "proposed_research": "Material needed: Comparator-specific content, exercise dose, contact time and supervision are needed. Estimates from different comparisons are not copied or pooled. This records needed materials; no new research was executed.", "current_reports": [ "R01", "R02", "R03", "R04" ], "existence": "Displayed selected and parent records exist in the stored summary. External availability, acquisition, content and reading of detailed materials remain separately unverified.", "acquired_read": "Complete stored parent Korean and English summary, selected question and bibliography read; external abstracts, full text, registration, protocols and analysis plans unread", "observation": "The original account distinguishes different exercise controls. An active-exercise label alone does not make them the same comparator or question.", "condition_status": "Partly verified", "status_reason": "This state links partial information and gaps in the preserved selected and parent accounts. External verification and clinical content review remain incomplete; it does not certify fulfilled conditions, efficacy, safety, prespecification or independence.", "missingness": "Comparator-specific content, exercise dose, contact time and supervision are needed. Estimates from different comparisons are not copied or pooled.", "uncertainty": "Target effects, endpoint-specific denominators, measurement, prespecified hierarchy, bias, externally validated important differences, durability, harms, independence and overlap remain unverified. Original numbers, historical verification narratives and registration identifiers are not promoted into new calculations, completed content review or clinical certification.", "review_date": null, "reading_status": "Full text not read · Stored summary read", "additional_material": "Comparator-specific content, exercise dose, contact time and supervision are needed. Estimates from different comparisons are not copied or pooled." }, { "item_id": "N17", "question_type": "Evidence condition", "question": "Were medication, medication timing and concurrent rehabilitation matched?", "needed": "Group-specific concurrent care and medication state", "role": "Required", "role_reason": "Material on Group-specific concurrent care and medication state is needed to connect the selected added-pole-effect question with population, walking controls, training dose, endpoints, time points, denominators, precision and harm boundaries.", "application_exception": "Selected pole C and absent individual score, status and axes are retained, distinguishing parent C54, separate program C and fall-and-durability D. Within-group improvement or standard-rehabilitation signals are not converted into added pole benefit; null results are not promoted into exact effect 0, equivalence or noninferiority. No new effects, CIs, denominators, totals, grades or individual-care guidance are created.", "criterion": "Original material on Group-specific concurrent care and medication state must link to the same ordinary-walking control, pole component, endpoint, time point and denominators, distinguishing standard-rehabilitation programs, other controls, parent context and unread external material.", "basis": "Preserved principles distinguishing questions, direct comparisons, reports and trials, endpoints, denominators, precision and harms informed production.", "condition_origin": "These are evidence conditions for the existing added-pole-effect question versus ordinary walking. They do not establish preregistration, execution of an official tool or completed clinical content review.", "proposed_research": "Material needed: Group medications, concurrent exercise and rehabilitation, medication timing, changes and withdrawal reasons are needed. Missing records are not treated as matched care. This records needed materials; no new research was executed.", "current_reports": [ "R01", "R02", "R03", "R04" ], "existence": "Displayed selected and parent records exist in the stored summary. External availability, acquisition, content and reading of detailed materials remain separately unverified.", "acquired_read": "Complete stored parent Korean and English summary, selected question and bibliography read; external abstracts, full text, registration, protocols and analysis plans unread", "observation": "The original safety narrative mentions medication-timing assessment, but the summary lacks trial-specific medication changes and ON/OFF state at measurement.", "condition_status": "Unverified", "status_reason": "This state links partial information and gaps in the preserved selected and parent accounts. External verification and clinical content review remain incomplete; it does not certify fulfilled conditions, efficacy, safety, prespecification or independence.", "missingness": "Group medications, concurrent exercise and rehabilitation, medication timing, changes and withdrawal reasons are needed. Missing records are not treated as matched care.", "uncertainty": "Target effects, endpoint-specific denominators, measurement, prespecified hierarchy, bias, externally validated important differences, durability, harms, independence and overlap remain unverified. Original numbers, historical verification narratives and registration identifiers are not promoted into new calculations, completed content review or clinical certification.", "review_date": null, "reading_status": "Full text not read · Stored summary read", "additional_material": "Group medications, concurrent exercise and rehabilitation, medication timing, changes and withdrawal reasons are needed. Missing records are not treated as matched care." }, { "item_id": "N18", "question_type": "Evidence condition", "question": "How do total samples differ from analysis denominators?", "needed": "Allocated, completed and endpoint-specific analysis samples", "role": "Required", "role_reason": "Material on Allocated, completed and endpoint-specific analysis samples is needed to connect the selected added-pole-effect question with population, walking controls, training dose, endpoints, time points, denominators, precision and harm boundaries.", "application_exception": "Selected pole C and absent individual score, status and axes are retained, distinguishing parent C54, separate program C and fall-and-durability D. Within-group improvement or standard-rehabilitation signals are not converted into added pole benefit; null results are not promoted into exact effect 0, equivalence or noninferiority. No new effects, CIs, denominators, totals, grades or individual-care guidance are created.", "criterion": "Original material on Allocated, completed and endpoint-specific analysis samples must link to the same ordinary-walking control, pole component, endpoint, time point and denominators, distinguishing standard-rehabilitation programs, other controls, parent context and unread external material.", "basis": "Preserved principles distinguishing questions, direct comparisons, reports and trials, endpoints, denominators, precision and harms informed production.", "condition_origin": "These are evidence conditions for the existing added-pole-effect question versus ordinary walking. They do not establish preregistration, execution of an official tool or completed clinical content review.", "proposed_research": "Material needed: Group allocation, completion, assessment and analysis counts, missing-data handling and ITT materials are needed. Differences and totals are not newly calculated or summed. This records needed materials; no new research was executed.", "current_reports": [ "R01", "R02", "R03", "R04" ], "existence": "Displayed selected and parent records exist in the stored summary. External availability, acquisition, content and reading of detailed materials remain separately unverified.", "acquired_read": "Complete stored parent Korean and English summary, selected question and bibliography read; external abstracts, full text, registration, protocols and analysis plans unread", "observation": "Reuter's 90 participants and 3 arms, Monteiro's 33 participants and 8 weeks with 32 completers in the citation, Szefler-Derela's 40 participants and 6 weeks, and Cugusi's 20-person pilot are distinguished.", "condition_status": "Partly verified", "status_reason": "This state links partial information and gaps in the preserved selected and parent accounts. External verification and clinical content review remain incomplete; it does not certify fulfilled conditions, efficacy, safety, prespecification or independence.", "missingness": "Group allocation, completion, assessment and analysis counts, missing-data handling and ITT materials are needed. Differences and totals are not newly calculated or summed.", "uncertainty": "Target effects, endpoint-specific denominators, measurement, prespecified hierarchy, bias, externally validated important differences, durability, harms, independence and overlap remain unverified. Original numbers, historical verification narratives and registration identifiers are not promoted into new calculations, completed content review or clinical certification.", "review_date": null, "reading_status": "Full text not read · Stored summary read", "additional_material": "Group allocation, completion, assessment and analysis counts, missing-data handling and ITT materials are needed. Differences and totals are not newly calculated or summed." }, { "item_id": "N19", "question_type": "Evidence condition", "question": "What is known about randomization and masking?", "needed": "Allocation, concealment, assessors, deviations and measurement", "role": "Required", "role_reason": "Material on Allocation, concealment, assessors, deviations and measurement is needed to connect the selected added-pole-effect question with population, walking controls, training dose, endpoints, time points, denominators, precision and harm boundaries.", "application_exception": "Selected pole C and absent individual score, status and axes are retained, distinguishing parent C54, separate program C and fall-and-durability D. Within-group improvement or standard-rehabilitation signals are not converted into added pole benefit; null results are not promoted into exact effect 0, equivalence or noninferiority. No new effects, CIs, denominators, totals, grades or individual-care guidance are created.", "criterion": "Original material on Allocation, concealment, assessors, deviations and measurement must link to the same ordinary-walking control, pole component, endpoint, time point and denominators, distinguishing standard-rehabilitation programs, other controls, parent context and unread external material.", "basis": "Preserved principles distinguishing questions, direct comparisons, reports and trials, endpoints, denominators, precision and harms informed production.", "condition_origin": "These are evidence conditions for the existing added-pole-effect question versus ordinary walking. They do not establish preregistration, execution of an official tool or completed clinical content review.", "proposed_research": "Material needed: Sequence generation, concealment, masking roles and maintenance, missingness, deviations and measurement procedures are needed. No new official RoB2 assessment is executed. This records needed materials; no new research was executed.", "current_reports": [ "R01", "R02", "R03", "R04" ], "existence": "Displayed selected and parent records exist in the stored summary. External availability, acquisition, content and reading of detailed materials remain separately unverified.", "acquired_read": "Complete stored parent Korean and English summary, selected question and bibliography read; external abstracts, full text, registration, protocols and analysis plans unread", "observation": "The stored evidence labels randomized trials, with single masking for Monteiro and lack of masking plus multiple endpoints for Reuter. Actual masking by role remains unverified.", "condition_status": "Partly verified", "status_reason": "This state links partial information and gaps in the preserved selected and parent accounts. External verification and clinical content review remain incomplete; it does not certify fulfilled conditions, efficacy, safety, prespecification or independence.", "missingness": "Sequence generation, concealment, masking roles and maintenance, missingness, deviations and measurement procedures are needed. No new official RoB2 assessment is executed.", "uncertainty": "Target effects, endpoint-specific denominators, measurement, prespecified hierarchy, bias, externally validated important differences, durability, harms, independence and overlap remain unverified. Original numbers, historical verification narratives and registration identifiers are not promoted into new calculations, completed content review or clinical certification.", "review_date": null, "reading_status": "Full text not read · Stored summary read", "additional_material": "Sequence generation, concealment, masking roles and maintenance, missingness, deviations and measurement procedures are needed. No new official RoB2 assessment is executed." }, { "item_id": "N20", "question_type": "Evidence condition", "question": "How do shared reports link to original trials?", "needed": "Report, cohort and participant overlap", "role": "Required", "role_reason": "Material on Report, cohort and participant overlap is needed to connect the selected added-pole-effect question with population, walking controls, training dose, endpoints, time points, denominators, precision and harm boundaries.", "application_exception": "Selected pole C and absent individual score, status and axes are retained, distinguishing parent C54, separate program C and fall-and-durability D. Within-group improvement or standard-rehabilitation signals are not converted into added pole benefit; null results are not promoted into exact effect 0, equivalence or noninferiority. No new effects, CIs, denominators, totals, grades or individual-care guidance are created.", "criterion": "Original material on Report, cohort and participant overlap must link to the same ordinary-walking control, pole component, endpoint, time point and denominators, distinguishing standard-rehabilitation programs, other controls, parent context and unread external material.", "basis": "Preserved principles distinguishing questions, direct comparisons, reports and trials, endpoints, denominators, precision and harms informed production.", "condition_origin": "These are evidence conditions for the existing added-pole-effect question versus ordinary walking. They do not establish preregistration, execution of an official tool or completed clinical content review.", "proposed_research": "Material needed: Author, institution, recruitment-period, registration and cohort links are needed. Report slots and sheets are not certified as unique trials, participants or independent replications. This records needed materials; no new research was executed.", "current_reports": [ "R01", "R02", "R03", "R04" ], "existence": "Displayed selected and parent records exist in the stored summary. External availability, acquisition, content and reading of detailed materials remain separately unverified.", "acquired_read": "Complete stored parent Korean and English summary, selected question and bibliography read; external abstracts, full text, registration, protocols and analysis plans unread", "observation": "Parent 3014 and its subclaims share reports. There are 3 original evidence entries and 4 citations; Cugusi is a bibliographic summary without a separate evidence entry.", "condition_status": "Partly verified", "status_reason": "This state links partial information and gaps in the preserved selected and parent accounts. External verification and clinical content review remain incomplete; it does not certify fulfilled conditions, efficacy, safety, prespecification or independence.", "missingness": "Author, institution, recruitment-period, registration and cohort links are needed. Report slots and sheets are not certified as unique trials, participants or independent replications.", "uncertainty": "Target effects, endpoint-specific denominators, measurement, prespecified hierarchy, bias, externally validated important differences, durability, harms, independence and overlap remain unverified. Original numbers, historical verification narratives and registration identifiers are not promoted into new calculations, completed content review or clinical certification.", "review_date": null, "reading_status": "Full text not read · Stored summary read", "additional_material": "Author, institution, recruitment-period, registration and cohort links are needed. Report slots and sheets are not certified as unique trials, participants or independent replications." }, { "item_id": "N21", "question_type": "Evidence condition", "question": "Were registration and prespecified plans actually read?", "needed": "Registration, protocols, SAPs and endpoint hierarchy", "role": "Required", "role_reason": "Material on Registration, protocols, SAPs and endpoint hierarchy is needed to connect the selected added-pole-effect question with population, walking controls, training dose, endpoints, time points, denominators, precision and harm boundaries.", "application_exception": "Selected pole C and absent individual score, status and axes are retained, distinguishing parent C54, separate program C and fall-and-durability D. Within-group improvement or standard-rehabilitation signals are not converted into added pole benefit; null results are not promoted into exact effect 0, equivalence or noninferiority. No new effects, CIs, denominators, totals, grades or individual-care guidance are created.", "criterion": "Original material on Registration, protocols, SAPs and endpoint hierarchy must link to the same ordinary-walking control, pole component, endpoint, time point and denominators, distinguishing standard-rehabilitation programs, other controls, parent context and unread external material.", "basis": "Preserved principles distinguishing questions, direct comparisons, reports and trials, endpoints, denominators, precision and harms informed production.", "condition_origin": "These are evidence conditions for the existing added-pole-effect question versus ordinary walking. They do not establish preregistration, execution of an official tool or completed clinical content review.", "proposed_research": "Material needed: Trial registration, change histories, protocols, SAPs and prespecified analyses are needed. Unverified registration is not asserted to be absent. This records needed materials; no new research was executed.", "current_reports": [ "R01", "R02", "R03", "R04" ], "existence": "Displayed selected and parent records exist in the stored summary. External availability, acquisition, content and reading of detailed materials remain separately unverified.", "acquired_read": "Complete stored parent Korean and English summary, selected question and bibliography read; external abstracts, full text, registration, protocols and analysis plans unread", "observation": "Original evidence records registration as unverified. The standard-rehabilitation report's prespecified-primary UPDRS-III narrative is separate context; registration and plans for the selected ordinary-walking trial remain unread.", "condition_status": "Partly verified", "status_reason": "This state links partial information and gaps in the preserved selected and parent accounts. External verification and clinical content review remain incomplete; it does not certify fulfilled conditions, efficacy, safety, prespecification or independence.", "missingness": "Trial registration, change histories, protocols, SAPs and prespecified analyses are needed. Unverified registration is not asserted to be absent.", "uncertainty": "Target effects, endpoint-specific denominators, measurement, prespecified hierarchy, bias, externally validated important differences, durability, harms, independence and overlap remain unverified. Original numbers, historical verification narratives and registration identifiers are not promoted into new calculations, completed content review or clinical certification.", "review_date": null, "reading_status": "Full text not read · Stored summary read", "additional_material": "Trial registration, change histories, protocols, SAPs and prespecified analyses are needed. Unverified registration is not asserted to be absent." }, { "item_id": "N22", "question_type": "Evidence condition", "question": "How were multiple endpoints and selective reporting handled?", "needed": "Prespecified hierarchy, multiplicity and complete results", "role": "Required", "role_reason": "Material on Prespecified hierarchy, multiplicity and complete results is needed to connect the selected added-pole-effect question with population, walking controls, training dose, endpoints, time points, denominators, precision and harm boundaries.", "application_exception": "Selected pole C and absent individual score, status and axes are retained, distinguishing parent C54, separate program C and fall-and-durability D. Within-group improvement or standard-rehabilitation signals are not converted into added pole benefit; null results are not promoted into exact effect 0, equivalence or noninferiority. No new effects, CIs, denominators, totals, grades or individual-care guidance are created.", "criterion": "Original material on Prespecified hierarchy, multiplicity and complete results must link to the same ordinary-walking control, pole component, endpoint, time point and denominators, distinguishing standard-rehabilitation programs, other controls, parent context and unread external material.", "basis": "Preserved principles distinguishing questions, direct comparisons, reports and trials, endpoints, denominators, precision and harms informed production.", "condition_origin": "These are evidence conditions for the existing added-pole-effect question versus ordinary walking. They do not establish preregistration, execution of an official tool or completed clinical content review.", "proposed_research": "Material needed: Original endpoint lists, analysis order, time points, multiplicity handling and complete results are needed. Selected positive findings are not expanded into recovery of every function. This records needed materials; no new research was executed.", "current_reports": [ "R01", "R02", "R03", "R04" ], "existence": "Displayed selected and parent records exist in the stored summary. External availability, acquisition, content and reading of detailed materials remain separately unverified.", "acquired_read": "Complete stored parent Korean and English summary, selected question and bibliography read; external abstracts, full text, registration, protocols and analysis plans unread", "observation": "The parent records small samples, lack of masking, multiple endpoints and selected functional signals. The primary endpoint and other outcomes are not combined at the same evidential level.", "condition_status": "Partly verified", "status_reason": "This state links partial information and gaps in the preserved selected and parent accounts. External verification and clinical content review remain incomplete; it does not certify fulfilled conditions, efficacy, safety, prespecification or independence.", "missingness": "Original endpoint lists, analysis order, time points, multiplicity handling and complete results are needed. Selected positive findings are not expanded into recovery of every function.", "uncertainty": "Target effects, endpoint-specific denominators, measurement, prespecified hierarchy, bias, externally validated important differences, durability, harms, independence and overlap remain unverified. Original numbers, historical verification narratives and registration identifiers are not promoted into new calculations, completed content review or clinical certification.", "review_date": null, "reading_status": "Full text not read · Stored summary read", "additional_material": "Original endpoint lists, analysis order, time points, multiplicity handling and complete results are needed. Selected positive findings are not expanded into recovery of every function." }, { "item_id": "N23", "question_type": "Evidence condition", "question": "Are funding, equipment, affiliation and analysis involvement separated?", "needed": "Separate checks of company involvement", "role": "Required", "role_reason": "Material on Separate checks of company involvement is needed to connect the selected added-pole-effect question with population, walking controls, training dose, endpoints, time points, denominators, precision and harm boundaries.", "application_exception": "Selected pole C and absent individual score, status and axes are retained, distinguishing parent C54, separate program C and fall-and-durability D. Within-group improvement or standard-rehabilitation signals are not converted into added pole benefit; null results are not promoted into exact effect 0, equivalence or noninferiority. No new effects, CIs, denominators, totals, grades or individual-care guidance are created.", "criterion": "Original material on Separate checks of company involvement must link to the same ordinary-walking control, pole component, endpoint, time point and denominators, distinguishing standard-rehabilitation programs, other controls, parent context and unread external material.", "basis": "Preserved principles distinguishing questions, direct comparisons, reports and trials, endpoints, denominators, precision and harms informed production.", "condition_origin": "These are evidence conditions for the existing added-pole-effect question versus ordinary walking. They do not establish preregistration, execution of an official tool or completed clinical content review.", "proposed_research": "Material needed: Disclosures on funding, equipment, company affiliation and COI, and design, analysis and publication involvement are needed. Public funding or no external funding does not certify absence of other involvement. This records needed materials; no new research was executed.", "current_reports": [ "R01", "R02", "R03", "R04" ], "existence": "Displayed selected and parent records exist in the stored summary. External availability, acquisition, content and reading of detailed materials remain separately unverified.", "acquired_read": "Complete stored parent Korean and English summary, selected question and bibliography read; external abstracts, full text, registration, protocols and analysis plans unread", "observation": "Specific Reuter funding is unverified. Monteiro records public funding and supplied poles; Szefler-Derela records no external funding and 1 author employed by Novartis. Cugusi funding remains unverified.", "condition_status": "Partly verified", "status_reason": "This state links partial information and gaps in the preserved selected and parent accounts. External verification and clinical content review remain incomplete; it does not certify fulfilled conditions, efficacy, safety, prespecification or independence.", "missingness": "Disclosures on funding, equipment, company affiliation and COI, and design, analysis and publication involvement are needed. Public funding or no external funding does not certify absence of other involvement.", "uncertainty": "Target effects, endpoint-specific denominators, measurement, prespecified hierarchy, bias, externally validated important differences, durability, harms, independence and overlap remain unverified. Original numbers, historical verification narratives and registration identifiers are not promoted into new calculations, completed content review or clinical certification.", "review_date": null, "reading_status": "Full text not read · Stored summary read", "additional_material": "Disclosures on funding, equipment, company affiliation and COI, and design, analysis and publication involvement are needed. Public funding or no external funding does not certify absence of other involvement." }, { "item_id": "N24", "question_type": "Evidence condition", "question": "What do the fall and injury records mean?", "needed": "Harm events, affected people, exposure and denominators", "role": "Supplementary", "role_reason": "Material on Harm events, affected people, exposure and denominators is needed to connect the selected added-pole-effect question with population, walking controls, training dose, endpoints, time points, denominators, precision and harm boundaries.", "application_exception": "Selected pole C and absent individual score, status and axes are retained, distinguishing parent C54, separate program C and fall-and-durability D. Within-group improvement or standard-rehabilitation signals are not converted into added pole benefit; null results are not promoted into exact effect 0, equivalence or noninferiority. No new effects, CIs, denominators, totals, grades or individual-care guidance are created.", "criterion": "Original material on Harm events, affected people, exposure and denominators must link to the same ordinary-walking control, pole component, endpoint, time point and denominators, distinguishing standard-rehabilitation programs, other controls, parent context and unread external material.", "basis": "Preserved principles distinguishing questions, direct comparisons, reports and trials, endpoints, denominators, precision and harms informed production.", "condition_origin": "These are evidence conditions for the existing added-pole-effect question versus ordinary walking. They do not establish preregistration, execution of an official tool or completed clinical content review.", "proposed_research": "Material needed: Active collection, severity, repeated events versus affected people, harm denominators, exposure and causality are needed. Event records are not calculated as incidence rates or fall-prevention effects. This records needed materials; no new research was executed.", "current_reports": [ "R01", "R02", "R03", "R04" ], "existence": "Displayed selected and parent records exist in the stored summary. External availability, acquisition, content and reading of detailed materials remain separately unverified.", "acquired_read": "Complete stored parent Korean and English summary, selected question and bibliography read; external abstracts, full text, registration, protocols and analysis plans unread", "observation": "Falls in the 6-month trial were 4 with Nordic walking, 4 with ordinary walking and 1 with flexibility and relaxation. The original also records sprains, shoulder pain and heat-related hypotension.", "condition_status": "Partly verified", "status_reason": "This state links partial information and gaps in the preserved selected and parent accounts. External verification and clinical content review remain incomplete; it does not certify fulfilled conditions, efficacy, safety, prespecification or independence.", "missingness": "Active collection, severity, repeated events versus affected people, harm denominators, exposure and causality are needed. Event records are not calculated as incidence rates or fall-prevention effects.", "uncertainty": "Target effects, endpoint-specific denominators, measurement, prespecified hierarchy, bias, externally validated important differences, durability, harms, independence and overlap remain unverified. Original numbers, historical verification narratives and registration identifiers are not promoted into new calculations, completed content review or clinical certification.", "review_date": null, "reading_status": "Full text not read · Stored summary read", "additional_material": "Active collection, severity, repeated events versus affected people, harm denominators, exposure and causality are needed. Event records are not calculated as incidence rates or fall-prevention effects." }, { "item_id": "N25", "question_type": "Evidence condition", "question": "Are safety boundaries for vulnerable patients established?", "needed": "Freezing, impaired balance, orthostatic hypotension and supervision", "role": "Supplementary", "role_reason": "Material on Freezing, impaired balance, orthostatic hypotension and supervision is needed to connect the selected added-pole-effect question with population, walking controls, training dose, endpoints, time points, denominators, precision and harm boundaries.", "application_exception": "Selected pole C and absent individual score, status and axes are retained, distinguishing parent C54, separate program C and fall-and-durability D. Within-group improvement or standard-rehabilitation signals are not converted into added pole benefit; null results are not promoted into exact effect 0, equivalence or noninferiority. No new effects, CIs, denominators, totals, grades or individual-care guidance are created.", "criterion": "Original material on Freezing, impaired balance, orthostatic hypotension and supervision must link to the same ordinary-walking control, pole component, endpoint, time point and denominators, distinguishing standard-rehabilitation programs, other controls, parent context and unread external material.", "basis": "Preserved principles distinguishing questions, direct comparisons, reports and trials, endpoints, denominators, precision and harms informed production.", "condition_origin": "These are evidence conditions for the existing added-pole-effect question versus ordinary walking. They do not establish preregistration, execution of an official tool or completed clinical content review.", "proposed_research": "Material needed: Vulnerable-patient eligibility and exclusions, assistance, supervision, stopping criteria and harms by medication state are needed. No new individual-care instructions or universal safety certification are created. This records needed materials; no new research was executed.", "current_reports": [ "R01", "R02", "R03", "R04" ], "existence": "Displayed selected and parent records exist in the stored summary. External availability, acquisition, content and reading of detailed materials remain separately unverified.", "acquired_read": "Complete stored parent Korean and English summary, selected question and bibliography read; external abstracts, full text, registration, protocols and analysis plans unread", "observation": "The original safety narrative states that poles do not correct freezing or orthostatic hypotension and records the need for professional assessment and a fall-prevention plan.", "condition_status": "Partly verified", "status_reason": "This state links partial information and gaps in the preserved selected and parent accounts. External verification and clinical content review remain incomplete; it does not certify fulfilled conditions, efficacy, safety, prespecification or independence.", "missingness": "Vulnerable-patient eligibility and exclusions, assistance, supervision, stopping criteria and harms by medication state are needed. No new individual-care instructions or universal safety certification are created.", "uncertainty": "Target effects, endpoint-specific denominators, measurement, prespecified hierarchy, bias, externally validated important differences, durability, harms, independence and overlap remain unverified. Original numbers, historical verification narratives and registration identifiers are not promoted into new calculations, completed content review or clinical certification.", "review_date": null, "reading_status": "Full text not read · Stored summary read", "additional_material": "Vulnerable-patient eligibility and exclusions, assistance, supervision, stopping criteria and harms by medication state are needed. No new individual-care instructions or universal safety certification are created." }, { "item_id": "N26", "question_type": "Evidence condition", "question": "What is known about post-training durability and harms?", "needed": "During-training duration versus post-training follow-up", "role": "Supplementary", "role_reason": "Material on During-training duration versus post-training follow-up is needed to connect the selected added-pole-effect question with population, walking controls, training dose, endpoints, time points, denominators, precision and harm boundaries.", "application_exception": "Selected pole C and absent individual score, status and axes are retained, distinguishing parent C54, separate program C and fall-and-durability D. Within-group improvement or standard-rehabilitation signals are not converted into added pole benefit; null results are not promoted into exact effect 0, equivalence or noninferiority. No new effects, CIs, denominators, totals, grades or individual-care guidance are created.", "criterion": "Original material on During-training duration versus post-training follow-up must link to the same ordinary-walking control, pole component, endpoint, time point and denominators, distinguishing standard-rehabilitation programs, other controls, parent context and unread external material.", "basis": "Preserved principles distinguishing questions, direct comparisons, reports and trials, endpoints, denominators, precision and harms informed production.", "condition_origin": "These are evidence conditions for the existing added-pole-effect question versus ordinary walking. They do not establish preregistration, execution of an official tool or completed clinical content review.", "proposed_research": "Material needed: Independent post-training follow-up, maintenance exercise, adherence, falls, injuries, rare harms and group denominators are needed. This records needed materials; no new research was executed.", "current_reports": [ "R01", "R02", "R03", "R04" ], "existence": "Displayed selected and parent records exist in the stored summary. External availability, acquisition, content and reading of detailed materials remain separately unverified.", "acquired_read": "Complete stored parent Korean and English summary, selected question and bibliography read; external abstracts, full text, registration, protocols and analysis plans unread", "observation": "Training lasting weeks to 6 months is not post-training durability evidence. The separate subclaim leaves fall prevention and post-training durability unestablished.", "condition_status": "Partly verified", "status_reason": "This state links partial information and gaps in the preserved selected and parent accounts. External verification and clinical content review remain incomplete; it does not certify fulfilled conditions, efficacy, safety, prespecification or independence.", "missingness": "Independent post-training follow-up, maintenance exercise, adherence, falls, injuries, rare harms and group denominators are needed.", "uncertainty": "Target effects, endpoint-specific denominators, measurement, prespecified hierarchy, bias, externally validated important differences, durability, harms, independence and overlap remain unverified. Original numbers, historical verification narratives and registration identifiers are not promoted into new calculations, completed content review or clinical certification.", "review_date": null, "reading_status": "Full text not read · Stored summary read", "additional_material": "Independent post-training follow-up, maintenance exercise, adherence, falls, injuries, rare harms and group denominators are needed." }, { "item_id": "N27", "question_type": "Evidence condition", "question": "How does stored-summary reading differ from external-original reading?", "needed": "Actual reading of summaries, abstracts, full texts, registration and plans", "role": "Required", "role_reason": "Material on Actual reading of summaries, abstracts, full texts, registration and plans is needed to connect the selected added-pole-effect question with population, walking controls, training dose, endpoints, time points, denominators, precision and harm boundaries.", "application_exception": "Selected pole C and absent individual score, status and axes are retained, distinguishing parent C54, separate program C and fall-and-durability D. Within-group improvement or standard-rehabilitation signals are not converted into added pole benefit; null results are not promoted into exact effect 0, equivalence or noninferiority. No new effects, CIs, denominators, totals, grades or individual-care guidance are created.", "criterion": "Original material on Actual reading of summaries, abstracts, full texts, registration and plans must link to the same ordinary-walking control, pole component, endpoint, time point and denominators, distinguishing standard-rehabilitation programs, other controls, parent context and unread external material.", "basis": "Preserved principles distinguishing questions, direct comparisons, reports and trials, endpoints, denominators, precision and harms informed production.", "condition_origin": "These are evidence conditions for the existing added-pole-effect question versus ordinary walking. They do not establish preregistration, execution of an official tool or completed clinical content review.", "proposed_research": "Material needed: Acquisition, access and reading histories for originals are needed. A URL is not promoted into actual full-text reading, successful access or completed content review. This records needed materials; no new research was executed.", "current_reports": [ "R01", "R02", "R03", "R04" ], "existence": "Displayed selected and parent records exist in the stored summary. External availability, acquisition, content and reading of detailed materials remain separately unverified.", "acquired_read": "Complete stored parent Korean and English summary, selected question and bibliography read; external abstracts, full text, registration, protocols and analysis plans unread", "observation": "The complete stored parent JSON was read. Historical citation-verification narratives and cross-check records are retained; external abstracts, full texts, registration, protocols and SAPs remain unread.", "condition_status": "Partly verified", "status_reason": "This state links partial information and gaps in the preserved selected and parent accounts. External verification and clinical content review remain incomplete; it does not certify fulfilled conditions, efficacy, safety, prespecification or independence.", "missingness": "Acquisition, access and reading histories for originals are needed. A URL is not promoted into actual full-text reading, successful access or completed content review.", "uncertainty": "Target effects, endpoint-specific denominators, measurement, prespecified hierarchy, bias, externally validated important differences, durability, harms, independence and overlap remain unverified. Original numbers, historical verification narratives and registration identifiers are not promoted into new calculations, completed content review or clinical certification.", "review_date": null, "reading_status": "Full text not read · Stored summary read", "additional_material": "Acquisition, access and reading histories for originals are needed. A URL is not promoted into actual full-text reading, successful access or completed content review." }, { "item_id": "N28", "question_type": "Evidence condition", "question": "How do bilingual wording and representative facets relate?", "needed": "Trial-specific populations, durations and comparisons", "role": "Required", "role_reason": "Material on Trial-specific populations, durations and comparisons is needed to connect the selected added-pole-effect question with population, walking controls, training dose, endpoints, time points, denominators, precision and harm boundaries.", "application_exception": "Selected pole C and absent individual score, status and axes are retained, distinguishing parent C54, separate program C and fall-and-durability D. Within-group improvement or standard-rehabilitation signals are not converted into added pole benefit; null results are not promoted into exact effect 0, equivalence or noninferiority. No new effects, CIs, denominators, totals, grades or individual-care guidance are created.", "criterion": "Original material on Trial-specific populations, durations and comparisons must link to the same ordinary-walking control, pole component, endpoint, time point and denominators, distinguishing standard-rehabilitation programs, other controls, parent context and unread external material.", "basis": "Preserved principles distinguishing questions, direct comparisons, reports and trials, endpoints, denominators, precision and harms informed production.", "condition_origin": "These are evidence conditions for the existing added-pole-effect question versus ordinary walking. They do not establish preregistration, execution of an official tool or completed clinical content review.", "proposed_research": "Material needed: Report-specific recruitment, programs, time points, endpoints and original terminology are needed. English translation is not labeled external English full-text verification. This records needed materials; no new research was executed.", "current_reports": [ "R01", "R02", "R03", "R04" ], "existence": "Displayed selected and parent records exist in the stored summary. External availability, acquisition, content and reading of detailed materials remain separately unverified.", "acquired_read": "Complete stored parent Korean and English summary, selected question and bibliography read; external abstracts, full text, registration, protocols and analysis plans unread", "observation": "Parent Korean, English and facets are retained. The representative 90-person, 6-month record is not used as a common value for the 40-person, 6-week or 33-person, 8-week comparisons.", "condition_status": "Partly verified", "status_reason": "This state links partial information and gaps in the preserved selected and parent accounts. External verification and clinical content review remain incomplete; it does not certify fulfilled conditions, efficacy, safety, prespecification or independence.", "missingness": "Report-specific recruitment, programs, time points, endpoints and original terminology are needed. English translation is not labeled external English full-text verification.", "uncertainty": "Target effects, endpoint-specific denominators, measurement, prespecified hierarchy, bias, externally validated important differences, durability, harms, independence and overlap remain unverified. Original numbers, historical verification narratives and registration identifiers are not promoted into new calculations, completed content review or clinical certification.", "review_date": null, "reading_status": "Full text not read · Stored summary read", "additional_material": "Report-specific recruitment, programs, time points, endpoints and original terminology are needed. English translation is not labeled external English full-text verification." }, { "item_id": "N29", "question_type": "Evidence condition", "question": "How do selected C and parent C54 differ?", "needed": "Selected grade versus parent score, axes and safety label", "role": "Required", "role_reason": "Material on Selected grade versus parent score, axes and safety label is needed to connect the selected added-pole-effect question with population, walking controls, training dose, endpoints, time points, denominators, precision and harm boundaries.", "application_exception": "Selected pole C and absent individual score, status and axes are retained, distinguishing parent C54, separate program C and fall-and-durability D. Within-group improvement or standard-rehabilitation signals are not converted into added pole benefit; null results are not promoted into exact effect 0, equivalence or noninferiority. No new effects, CIs, denominators, totals, grades or individual-care guidance are created.", "criterion": "Original material on Selected grade versus parent score, axes and safety label must link to the same ordinary-walking control, pole component, endpoint, time point and denominators, distinguishing standard-rehabilitation programs, other controls, parent context and unread external material.", "basis": "Preserved principles distinguishing questions, direct comparisons, reports and trials, endpoints, denominators, precision and harms informed production.", "condition_origin": "These are evidence conditions for the existing added-pole-effect question versus ordinary walking. They do not establish preregistration, execution of an official tool or completed clinical content review.", "proposed_research": "Material needed: The selected-to-parent application boundary and original values must be preserved. No new grade, score or independent clinical certification is created. This records needed materials; no new research was executed.", "current_reports": [ "R01", "R02", "R03", "R04" ], "existence": "Displayed selected and parent records exist in the stored summary. External availability, acquisition, content and reading of detailed materials remain separately unverified.", "acquired_read": "Complete stored parent Korean and English summary, selected question and bibliography read; external abstracts, full text, registration, protocols and analysis plans unread", "observation": "Selected C has no individual score, status or axes. Parent C54, Caution and B/P/R1/I2/E+/B2/CX remain parent context; the lower C narrative for the pole question is not converted into a new score.", "condition_status": "Partly verified", "status_reason": "This state links partial information and gaps in the preserved selected and parent accounts. External verification and clinical content review remain incomplete; it does not certify fulfilled conditions, efficacy, safety, prespecification or independence.", "missingness": "The selected-to-parent application boundary and original values must be preserved. No new grade, score or independent clinical certification is created.", "uncertainty": "Target effects, endpoint-specific denominators, measurement, prespecified hierarchy, bias, externally validated important differences, durability, harms, independence and overlap remain unverified. Original numbers, historical verification narratives and registration identifiers are not promoted into new calculations, completed content review or clinical certification.", "review_date": null, "reading_status": "Full text not read · Stored summary read", "additional_material": "The selected-to-parent application boundary and original values must be preserved. No new grade, score or independent clinical certification is created." }, { "item_id": "N30", "question_type": "Evidence condition", "question": "How are evidence dates, production and correction events separated?", "needed": "Original evidence date, empty corrections and update records", "role": "Required", "role_reason": "Material on Original evidence date, empty corrections and update records is needed to connect the selected added-pole-effect question with population, walking controls, training dose, endpoints, time points, denominators, precision and harm boundaries.", "application_exception": "Selected pole C and absent individual score, status and axes are retained, distinguishing parent C54, separate program C and fall-and-durability D. Within-group improvement or standard-rehabilitation signals are not converted into added pole benefit; null results are not promoted into exact effect 0, equivalence or noninferiority. No new effects, CIs, denominators, totals, grades or individual-care guidance are created.", "criterion": "Original material on Original evidence date, empty corrections and update records must link to the same ordinary-walking control, pole component, endpoint, time point and denominators, distinguishing standard-rehabilitation programs, other controls, parent context and unread external material.", "basis": "Preserved principles distinguishing questions, direct comparisons, reports and trials, endpoints, denominators, precision and harms informed production.", "condition_origin": "These are evidence conditions for the existing added-pole-effect question versus ordinary walking. They do not establish preregistration, execution of an official tool or completed clinical content review.", "proposed_research": "Material needed: Material additions, condition revisions and verdict changes must remain separate events. Corrections or new evidence absent from the original are not invented. This records needed materials; no new research was executed.", "current_reports": [ "R01", "R02", "R03", "R04" ], "existence": "Displayed selected and parent records exist in the stored summary. External availability, acquisition, content and reading of detailed materials remain separately unverified.", "acquired_read": "Complete stored parent Korean and English summary, selected question and bibliography read; external abstracts, full text, registration, protocols and analysis plans unread", "observation": "The existing evidence date 2026-09-07, empty corrections array and empty deliberation string are retained. The production date does not replace them as a new evidence-verification date.", "condition_status": "Partly verified", "status_reason": "This state links partial information and gaps in the preserved selected and parent accounts. External verification and clinical content review remain incomplete; it does not certify fulfilled conditions, efficacy, safety, prespecification or independence.", "missingness": "Material additions, condition revisions and verdict changes must remain separate events. Corrections or new evidence absent from the original are not invented.", "uncertainty": "Target effects, endpoint-specific denominators, measurement, prespecified hierarchy, bias, externally validated important differences, durability, harms, independence and overlap remain unverified. Original numbers, historical verification narratives and registration identifiers are not promoted into new calculations, completed content review or clinical certification.", "review_date": null, "reading_status": "Full text not read · Stored summary read", "additional_material": "Material additions, condition revisions and verdict changes must remain separate events. Corrections or new evidence absent from the original are not invented." } ], "reports": [ { "report_id": "R01", "title": "Reuter I et al. 2011", "url": "https://pubmed.ncbi.nlm.nih.gov/21603199/", "report_type": "3-arm randomized flexibility, walking and Nordic-walking trial", "existence": "Reports and bibliographic records exist in the parent account. External original-material acquisition and reading remain unverified in this work.", "acquired_read": "The complete stored parent Korean and English accounts, original evidence and citations were read. External abstracts, full texts, registration, protocols and SAPs remain unread.", "study_family": "Parent 3014 and the standard-rehabilitation, added-pole-effect, and falls-and-durability subclaims share reports. Reuter, Cugusi, Monteiro and Szefler-Derela are distinguished by controls, durations, endpoints and denominators; reports and sheets are not added into new unique trial, participant or independent-replication counts. Those totals remain unverified.", "independent_replication": "Parent 3014 and the standard-rehabilitation, added-pole-effect, and falls-and-durability subclaims share reports. Reuter, Cugusi, Monteiro and Szefler-Derela are distinguished by controls, durations, endpoints and denominators; reports and sheets are not added into new unique trial, participant or independent-replication counts. Those totals remain unverified.", "observed_result": "Selected posture, stride and variability superiority was summarized in a 90-person, 6-month trial.", "result_level": "These are selected-measure signals from a multi-arm trial including ordinary-walking and flexibility controls. Exact comparator-specific contrasts, time points, between-group values and CIs are unlinked; the signals are not expanded into all pole effects or used to remove another null direct walking result.", "source_evidence_date": "2026-09-07", "materials": [ { "material_type": "Stored existing review summary", "public_status": "Preserved copy of the complete parent-verdict stored summary", "access_status": "Stored summary", "acquired": true, "actually_read": "Summary read", "as_of": "2026-09-07", "qualification": "PMID21603199 and DOI10.4061/2011/232473 are retained. Academic-study, specific-funding-unverified, multiple-endpoint and unmasked descriptions are original records. The stored summary date 2026-09-07 is a historical evidence date. Dates for unread external materials were originally unrecorded; acquisition, access, reading and current completed-review dates are not filled in. Unverified registration identifiers are not converted into absence of registration." }, { "material_type": "External abstract", "public_status": "Original bibliographic link or needed material; external public availability/access status unverified", "access_status": "Unread; access not attempted", "acquired": false, "actually_read": "Not read", "as_of": null, "qualification": "PMID21603199 and DOI10.4061/2011/232473 are retained. Academic-study, specific-funding-unverified, multiple-endpoint and unmasked descriptions are original records. The stored summary date 2026-09-07 is a historical evidence date. Dates for unread external materials were originally unrecorded; acquisition, access, reading and current completed-review dates are not filled in. Unverified registration identifiers are not converted into absence of registration." }, { "material_type": "External full text", "public_status": "Original bibliographic link or needed material; external public availability/access status unverified", "access_status": "Unread; access not attempted", "acquired": false, "actually_read": "Not read", "as_of": null, "qualification": "PMID21603199 and DOI10.4061/2011/232473 are retained. Academic-study, specific-funding-unverified, multiple-endpoint and unmasked descriptions are original records. The stored summary date 2026-09-07 is a historical evidence date. Dates for unread external materials were originally unrecorded; acquisition, access, reading and current completed-review dates are not filled in. Unverified registration identifiers are not converted into absence of registration." }, { "material_type": "Registration material", "public_status": "Original bibliographic link or needed material; external public availability/access status unverified", "access_status": "Unread; access not attempted", "acquired": false, "actually_read": "Not read", "as_of": null, "qualification": "PMID21603199 and DOI10.4061/2011/232473 are retained. Academic-study, specific-funding-unverified, multiple-endpoint and unmasked descriptions are original records. The stored summary date 2026-09-07 is a historical evidence date. Dates for unread external materials were originally unrecorded; acquisition, access, reading and current completed-review dates are not filled in. Unverified registration identifiers are not converted into absence of registration." }, { "material_type": "Protocol and analysis plan", "public_status": "Original bibliographic link or needed material; external public availability/access status unverified", "access_status": "Unread; access not attempted", "acquired": false, "actually_read": "Not read", "as_of": null, "qualification": "PMID21603199 and DOI10.4061/2011/232473 are retained. Academic-study, specific-funding-unverified, multiple-endpoint and unmasked descriptions are original records. The stored summary date 2026-09-07 is a historical evidence date. Dates for unread external materials were originally unrecorded; acquisition, access, reading and current completed-review dates are not filled in. Unverified registration identifiers are not converted into absence of registration." } ], "links": [ { "label": "PubMed", "url": "https://pubmed.ncbi.nlm.nih.gov/21603199/" } ] }, { "report_id": "R02", "title": "Cugusi L et al. 2017 · Bibliographic summary", "url": "https://pubmed.ncbi.nlm.nih.gov/27798812/", "report_type": "Citation-only randomized treadmill-control pilot", "existence": "Reports and bibliographic records exist in the parent account. External original-material acquisition and reading remain unverified in this work.", "acquired_read": "The complete stored parent Korean and English accounts, original evidence and citations were read. External abstracts, full texts, registration, protocols and SAPs remain unread.", "study_family": "Parent 3014 and the standard-rehabilitation, added-pole-effect, and falls-and-durability subclaims share reports. Reuter, Cugusi, Monteiro and Szefler-Derela are distinguished by controls, durations, endpoints and denominators; reports and sheets are not added into new unique trial, participant or independent-replication counts. Those totals remain unverified.", "independent_replication": "Parent 3014 and the standard-rehabilitation, added-pole-effect, and falls-and-durability subclaims share reports. Reuter, Cugusi, Monteiro and Szefler-Derela are distinguished by controls, durations, endpoints and denominators; reports and sheets are not added into new unique trial, participant or independent-replication counts. Those totals remain unverified.", "observed_result": "The original citation summarizes functional signals from a 20-person treadmill pilot.", "result_level": "This is a citation-only treadmill pilot without a separate original evidence entry, exact effects or CIs. Separation of exercise dose, instruction and the pole component remains unverified. Values from other trials are not copied.", "source_evidence_date": "2026-09-07", "materials": [ { "material_type": "Stored existing review summary", "public_status": "Preserved copy of the complete parent-verdict stored summary", "access_status": "Stored summary", "acquired": true, "actually_read": "Summary read", "as_of": "2026-09-07", "qualification": "This is the citation-only pilot with PMID27798812 and DOI10.1007/s40520-016-0648-9. No separate original evidence entry or quantitative effect is created. The stored summary date 2026-09-07 is a historical evidence date. Dates for unread external materials were originally unrecorded; acquisition, access, reading and current completed-review dates are not filled in. Unverified registration identifiers are not converted into absence of registration." }, { "material_type": "External abstract", "public_status": "Original bibliographic link or needed material; external public availability/access status unverified", "access_status": "Unread; access not attempted", "acquired": false, "actually_read": "Not read", "as_of": null, "qualification": "This is the citation-only pilot with PMID27798812 and DOI10.1007/s40520-016-0648-9. No separate original evidence entry or quantitative effect is created. The stored summary date 2026-09-07 is a historical evidence date. Dates for unread external materials were originally unrecorded; acquisition, access, reading and current completed-review dates are not filled in. Unverified registration identifiers are not converted into absence of registration." }, { "material_type": "External full text", "public_status": "Original bibliographic link or needed material; external public availability/access status unverified", "access_status": "Unread; access not attempted", "acquired": false, "actually_read": "Not read", "as_of": null, "qualification": "This is the citation-only pilot with PMID27798812 and DOI10.1007/s40520-016-0648-9. No separate original evidence entry or quantitative effect is created. The stored summary date 2026-09-07 is a historical evidence date. Dates for unread external materials were originally unrecorded; acquisition, access, reading and current completed-review dates are not filled in. Unverified registration identifiers are not converted into absence of registration." }, { "material_type": "Registration material", "public_status": "Original bibliographic link or needed material; external public availability/access status unverified", "access_status": "Unread; access not attempted", "acquired": false, "actually_read": "Not read", "as_of": null, "qualification": "This is the citation-only pilot with PMID27798812 and DOI10.1007/s40520-016-0648-9. No separate original evidence entry or quantitative effect is created. The stored summary date 2026-09-07 is a historical evidence date. Dates for unread external materials were originally unrecorded; acquisition, access, reading and current completed-review dates are not filled in. Unverified registration identifiers are not converted into absence of registration." }, { "material_type": "Protocol and analysis plan", "public_status": "Original bibliographic link or needed material; external public availability/access status unverified", "access_status": "Unread; access not attempted", "acquired": false, "actually_read": "Not read", "as_of": null, "qualification": "This is the citation-only pilot with PMID27798812 and DOI10.1007/s40520-016-0648-9. No separate original evidence entry or quantitative effect is created. The stored summary date 2026-09-07 is a historical evidence date. Dates for unread external materials were originally unrecorded; acquisition, access, reading and current completed-review dates are not filled in. Unverified registration identifiers are not converted into absence of registration." } ], "links": [ { "label": "PubMed", "url": "https://pubmed.ncbi.nlm.nih.gov/27798812/" } ] }, { "report_id": "R03", "title": "Monteiro EP et al. 2021", "url": "https://pubmed.ncbi.nlm.nih.gov/32529596/", "report_type": "Single-blind randomized Nordic-walking versus ordinary-walking trial", "existence": "Reports and bibliographic records exist in the parent account. External original-material acquisition and reading remain unverified in this work.", "acquired_read": "The complete stored parent Korean and English accounts, original evidence and citations were read. External abstracts, full texts, registration, protocols and SAPs remain unread.", "study_family": "Parent 3014 and the standard-rehabilitation, added-pole-effect, and falls-and-durability subclaims share reports. Reuter, Cugusi, Monteiro and Szefler-Derela are distinguished by controls, durations, endpoints and denominators; reports and sheets are not added into new unique trial, participant or independent-replication counts. Those totals remain unverified.", "independent_replication": "Parent 3014 and the standard-rehabilitation, added-pole-effect, and falls-and-durability subclaims share reports. Reuter, Cugusi, Monteiro and Szefler-Derela are distinguished by controls, durations, endpoints and denominators; reports and sheets are not added into new unique trial, participant or independent-replication counts. Those totals remain unverified.", "observed_result": "The 33-person, 8-week report records no superiority with UPDRS group-by-time P=.352. The original citation separately records 32 completers.", "result_level": "This is the core direct ordinary-walking comparison for the selected question. The null UPDRS group-by-time result, lack of superiority and citation's all-null narrative are retained, while exact scale scope, complete endpoint tables, effects, CIs and denominators remain unverified. Null results are not converted into exact effect 0, equivalence or noninferiority.", "source_evidence_date": "2026-09-07", "materials": [ { "material_type": "Stored existing review summary", "public_status": "Preserved copy of the complete parent-verdict stored summary", "access_status": "Stored summary", "acquired": true, "actually_read": "Summary read", "as_of": "2026-09-07", "qualification": "PMID32529596 and DOI10.1007/s40520-020-01617-w are retained. Public-funding and supplied-pole narratives are distinguished without promotion into independence certification. The stored summary date 2026-09-07 is a historical evidence date. Dates for unread external materials were originally unrecorded; acquisition, access, reading and current completed-review dates are not filled in. Unverified registration identifiers are not converted into absence of registration." }, { "material_type": "External abstract", "public_status": "Original bibliographic link or needed material; external public availability/access status unverified", "access_status": "Unread; access not attempted", "acquired": false, "actually_read": "Not read", "as_of": null, "qualification": "PMID32529596 and DOI10.1007/s40520-020-01617-w are retained. Public-funding and supplied-pole narratives are distinguished without promotion into independence certification. The stored summary date 2026-09-07 is a historical evidence date. Dates for unread external materials were originally unrecorded; acquisition, access, reading and current completed-review dates are not filled in. Unverified registration identifiers are not converted into absence of registration." }, { "material_type": "External full text", "public_status": "Original bibliographic link or needed material; external public availability/access status unverified", "access_status": "Unread; access not attempted", "acquired": false, "actually_read": "Not read", "as_of": null, "qualification": "PMID32529596 and DOI10.1007/s40520-020-01617-w are retained. Public-funding and supplied-pole narratives are distinguished without promotion into independence certification. The stored summary date 2026-09-07 is a historical evidence date. Dates for unread external materials were originally unrecorded; acquisition, access, reading and current completed-review dates are not filled in. Unverified registration identifiers are not converted into absence of registration." }, { "material_type": "Registration material", "public_status": "Original bibliographic link or needed material; external public availability/access status unverified", "access_status": "Unread; access not attempted", "acquired": false, "actually_read": "Not read", "as_of": null, "qualification": "PMID32529596 and DOI10.1007/s40520-020-01617-w are retained. Public-funding and supplied-pole narratives are distinguished without promotion into independence certification. The stored summary date 2026-09-07 is a historical evidence date. Dates for unread external materials were originally unrecorded; acquisition, access, reading and current completed-review dates are not filled in. Unverified registration identifiers are not converted into absence of registration." }, { "material_type": "Protocol and analysis plan", "public_status": "Original bibliographic link or needed material; external public availability/access status unverified", "access_status": "Unread; access not attempted", "acquired": false, "actually_read": "Not read", "as_of": null, "qualification": "PMID32529596 and DOI10.1007/s40520-020-01617-w are retained. Public-funding and supplied-pole narratives are distinguished without promotion into independence certification. The stored summary date 2026-09-07 is a historical evidence date. Dates for unread external materials were originally unrecorded; acquisition, access, reading and current completed-review dates are not filled in. Unverified registration identifiers are not converted into absence of registration." } ], "links": [ { "label": "PubMed", "url": "https://pubmed.ncbi.nlm.nih.gov/32529596/" } ] }, { "report_id": "R04", "title": "Szefler-Derela J et al. 2020", "url": "https://pubmed.ncbi.nlm.nih.gov/32708938/", "report_type": "Randomized Nordic-walking versus standard-rehabilitation trial", "existence": "Reports and bibliographic records exist in the parent account. External original-material acquisition and reading remain unverified in this work.", "acquired_read": "The complete stored parent Korean and English accounts, original evidence and citations were read. External abstracts, full texts, registration, protocols and SAPs remain unread.", "study_family": "Parent 3014 and the standard-rehabilitation, added-pole-effect, and falls-and-durability subclaims share reports. Reuter, Cugusi, Monteiro and Szefler-Derela are distinguished by controls, durations, endpoints and denominators; reports and sheets are not added into new unique trial, participant or independent-replication counts. Those totals remain unverified.", "independent_replication": "Parent 3014 and the standard-rehabilitation, added-pole-effect, and falls-and-durability subclaims share reports. Reuter, Cugusi, Monteiro and Szefler-Derela are distinguished by controls, durations, endpoints and denominators; reports and sheets are not added into new unique trial, participant or independent-replication counts. Those totals remain unverified.", "observed_result": "Median UPDRS-III reductions of 8.5 versus 6.0, P=.047 and null DGI P=.064 in the 40-person, 6-week trial are distinguished.", "result_level": "This is a separate whole-program comparison versus standard rehabilitation. The original primary UPDRS-III signal and null DGI are retained without conversion into the same evidence for added pole benefit over ordinary walking. Registration, plans, original CIs and denominators remain unread or unverified.", "source_evidence_date": "2026-09-07", "materials": [ { "material_type": "Stored existing review summary", "public_status": "Preserved copy of the complete parent-verdict stored summary", "access_status": "Stored summary", "acquired": true, "actually_read": "Summary read", "as_of": "2026-09-07", "qualification": "PMID32708938 and DOI10.3390/medicina56070356 are retained. Both reported absence of external funding and 1 author employed by Novartis are preserved. The stored summary date 2026-09-07 is a historical evidence date. Dates for unread external materials were originally unrecorded; acquisition, access, reading and current completed-review dates are not filled in. Unverified registration identifiers are not converted into absence of registration." }, { "material_type": "External abstract", "public_status": "Original bibliographic link or needed material; external public availability/access status unverified", "access_status": "Unread; access not attempted", "acquired": false, "actually_read": "Not read", "as_of": null, "qualification": "PMID32708938 and DOI10.3390/medicina56070356 are retained. Both reported absence of external funding and 1 author employed by Novartis are preserved. The stored summary date 2026-09-07 is a historical evidence date. Dates for unread external materials were originally unrecorded; acquisition, access, reading and current completed-review dates are not filled in. Unverified registration identifiers are not converted into absence of registration." }, { "material_type": "External full text", "public_status": "Original bibliographic link or needed material; external public availability/access status unverified", "access_status": "Unread; access not attempted", "acquired": false, "actually_read": "Not read", "as_of": null, "qualification": "PMID32708938 and DOI10.3390/medicina56070356 are retained. Both reported absence of external funding and 1 author employed by Novartis are preserved. The stored summary date 2026-09-07 is a historical evidence date. Dates for unread external materials were originally unrecorded; acquisition, access, reading and current completed-review dates are not filled in. Unverified registration identifiers are not converted into absence of registration." }, { "material_type": "Registration material", "public_status": "Original bibliographic link or needed material; external public availability/access status unverified", "access_status": "Unread; access not attempted", "acquired": false, "actually_read": "Not read", "as_of": null, "qualification": "PMID32708938 and DOI10.3390/medicina56070356 are retained. Both reported absence of external funding and 1 author employed by Novartis are preserved. The stored summary date 2026-09-07 is a historical evidence date. Dates for unread external materials were originally unrecorded; acquisition, access, reading and current completed-review dates are not filled in. Unverified registration identifiers are not converted into absence of registration." }, { "material_type": "Protocol and analysis plan", "public_status": "Original bibliographic link or needed material; external public availability/access status unverified", "access_status": "Unread; access not attempted", "acquired": false, "actually_read": "Not read", "as_of": null, "qualification": "PMID32708938 and DOI10.3390/medicina56070356 are retained. Both reported absence of external funding and 1 author employed by Novartis are preserved. The stored summary date 2026-09-07 is a historical evidence date. Dates for unread external materials were originally unrecorded; acquisition, access, reading and current completed-review dates are not filled in. Unverified registration identifiers are not converted into absence of registration." } ], "links": [ { "label": "PubMed", "url": "https://pubmed.ncbi.nlm.nih.gov/32708938/" } ] } ], "method_sources": [ { "id": "M03", "version": "Cochrane Handbook 6.5 (2024), chapter updated 2023-08", "url": "https://www.cochrane.org/authors/handbooks-and-manuals/handbook/current/chapter-03", "section": "§3.1, §3.2.1–3.2.3, MECIR C5/C7/C13", "official_principle": "Clearly record the question, eligibility conditions and reasons for changes, and distinguish variations in interventions.", "review_level": "Existing methodological links were reused for production. External originals were not reread and methodological content was not reassessed." }, { "id": "M04", "version": "Cochrane Handbook 6.5.1 (2025), chapter updated 2025-03", "url": "https://www.cochrane.org/authors/handbooks-and-manuals/handbook/current/chapter-04", "section": "§4.5, §4.6.1–4.6.3, MECIR C42", "official_principle": "Distinguish studies from reports and link them; do not omit a study solely because results are unreported.", "review_level": "Existing methodological links were reused for production. External originals were not reread and methodological content was not reassessed." }, { "id": "M08", "version": "Cochrane Handbook 6.5 (2024), chapter updated 2019-10", "url": "https://www.cochrane.org/authors/handbooks-and-manuals/handbook/current/chapter-08", "section": "§8.1–8.2.3, Table 8.2.a", "official_principle": "Define the outcome and effect of interest, then examine randomization, deviations, missing data, measurement and selective reporting.", "review_level": "Existing methodological links were reused for production. External originals were not reread and methodological content was not reassessed." }, { "id": "M15", "version": "Cochrane Handbook 6.5 (2024), chapter updated 2023-08", "url": "https://www.cochrane.org/authors/handbooks-and-manuals/handbook/current/chapter-15", "section": "§15.2.4, §15.3.1–15.3.3", "official_principle": "Distinguish effect estimates, intervals, importance and applicability. Sample size alone does not determine precision.", "review_level": "Existing methodological links were reused for production. External originals were not reread and methodological content was not reassessed." }, { "id": "M19", "version": "Cochrane Handbook 6.5 (2024), chapter updated 2019-10", "url": "https://www.cochrane.org/authors/handbooks-and-manuals/handbook/current/chapter-19", "section": "§19.1.2, §19.2.1–19.2.4", "official_principle": "Harm questions may require different designs, populations and follow-up from efficacy questions. Case reports do not establish incidence rates.", "review_level": "Existing methodological links were reused for production. External originals were not reread and methodological content was not reassessed." } ], "status_dictionary": { "Partly verified": "Partial information from the stored summary is linked; detailed originals and content review remain incomplete.", "Unverified": "Required details cannot be established within the preserved scope. This does not establish absence of effects or studies, or safety.", "Review incomplete": "Review of existing content remains incomplete.", "Met": "This state is used only within the relevant conditions after material verification and content review. It was not automatically assigned in this work.", "Not reported": "Unreported within material actually read. Unread external material is not relabeled as unreported.", "Inaccessible": "This means actual access failure. External access was not attempted in this work, so this state was not assigned.", "Not applicable": "Used only with an application exception and reason based on the question scope.", "Conflicting data": "This requires actual comparison of materials; no new conflict judgment was made in this work.", "Insufficient evidence for the conditions": "This indicates gaps in additional material for the selected conditions. Unread material as a whole is not converted into an efficacy grade." }, "study_overlap": { "state": "Unverified", "unique_trial_count": null, "unique_participant_count": null, "reason": "Parent 3014 and the standard-rehabilitation, added-pole-effect, and falls-and-durability subclaims share reports. Reuter, Cugusi, Monteiro and Szefler-Derela are distinguished by controls, durations, endpoints and denominators; reports and sheets are not added into new unique trial, participant or independent-replication counts. Those totals remain unverified." }, "history": [ { "date": "2026-10-21", "kind": "Separation of public-facing pages and materials", "view_version": "1.0", "change": "Public-facing views and materials were prepared from the existing 30 items. No new clinical search, verification-status change or scoring was performed." } ], "language": "en", "translation_date": "2026-10-21" }