{
  "schema_version": "chamgap-public-criteria-1.0",
  "title": "Stand-Alone Single-Leg Standing × Overall Hip BMD — Null Overall; Signal in a Small Age Subgroup · Evidence and Gaps Sheet",
  "language": "en",
  "translation_date": "2026-10-19",
  "criteria_version": "1.0",
  "criteria_date": "2026-10-06",
  "condition_origin": "Chamgap's own application conditions",
  "method_sources": [
    {
      "id": "M03",
      "version": "Cochrane Handbook 6.5 (2024), chapter updated 2023-08",
      "url": "https://www.cochrane.org/authors/handbooks-and-manuals/handbook/current/chapter-03",
      "section": "§3.1, §3.2.1–3.2.3, MECIR C5/C7/C13",
      "official_principle": "Clearly record the question, eligibility conditions and reasons for changes, and distinguish variations in interventions.",
      "review_level": "Existing methodological links were reused for production. External originals were not reread and methodological content was not reassessed."
    },
    {
      "id": "M04",
      "version": "Cochrane Handbook 6.5.1 (2025), chapter updated 2025-03",
      "url": "https://www.cochrane.org/authors/handbooks-and-manuals/handbook/current/chapter-04",
      "section": "§4.5, §4.6.1–4.6.3, MECIR C42",
      "official_principle": "Distinguish studies from reports and link them; do not omit a study solely because results are unreported.",
      "review_level": "Existing methodological links were reused for production. External originals were not reread and methodological content was not reassessed."
    },
    {
      "id": "M08",
      "version": "Cochrane Handbook 6.5 (2024), chapter updated 2019-10",
      "url": "https://www.cochrane.org/authors/handbooks-and-manuals/handbook/current/chapter-08",
      "section": "§8.1–8.2.3, Table 8.2.a",
      "official_principle": "Define the outcome and effect of interest, then examine randomization, deviations, missing data, measurement and selective reporting.",
      "review_level": "Existing methodological links were reused for production. External originals were not reread and methodological content was not reassessed."
    },
    {
      "id": "M15",
      "version": "Cochrane Handbook 6.5 (2024), chapter updated 2023-08",
      "url": "https://www.cochrane.org/authors/handbooks-and-manuals/handbook/current/chapter-15",
      "section": "§15.2.4, §15.3.1–15.3.3",
      "official_principle": "Distinguish effect estimates, intervals, importance and applicability. Sample size alone does not determine precision.",
      "review_level": "Existing methodological links were reused for production. External originals were not reread and methodological content was not reassessed."
    },
    {
      "id": "M19",
      "version": "Cochrane Handbook 6.5 (2024), chapter updated 2019-10",
      "url": "https://www.cochrane.org/authors/handbooks-and-manuals/handbook/current/chapter-19",
      "section": "§19.1.2, §19.2.1–19.2.4",
      "official_principle": "Harm questions may require different designs, populations and follow-up from efficacy questions. Case reports do not establish incidence rates.",
      "review_level": "Existing methodological links were reused for production. External originals were not reread and methodological content was not reassessed."
    }
  ],
  "status_dictionary": {
    "Partly verified": "Partial information from the stored summary is linked; detailed originals and content review remain incomplete.",
    "Unverified": "Required details cannot be established within the preserved scope. This does not establish absence of effects or studies, or safety.",
    "Review incomplete": "Review of existing content remains incomplete.",
    "Met": "This state is used only within the relevant conditions after material verification and content review. It was not automatically assigned in this work.",
    "Not reported": "Unreported within material actually read. Unread external material is not relabeled as unreported.",
    "Inaccessible": "This means actual access failure. External access was not attempted in this work, so this state was not assigned.",
    "Not applicable": "Used only with an application exception and reason based on the question scope.",
    "Conflicting data": "This requires actual comparison of materials; no new conflict judgment was made in this work.",
    "Insufficient evidence for the conditions": "This indicates gaps in additional material for the selected conditions. Unread material as a whole is not converted into an efficacy grade."
  },
  "requirements": [
    {
      "item_id": "N01",
      "question_type": "Evidence condition",
      "question": "Which existing BMD question and verdict are being transferred?",
      "needed": "Original claim, grade and explanation for increased overall hip BMD",
      "role": "Required",
      "role_reason": "This condition connects Original claim, grade and explanation for increased overall hip BMD with populations, comparators, measurement sites, ROIs, overall and subgroup findings, denominators, timing, prespecification, precision, reports, errata and harms for the selected overall-hip-BMD question.",
      "application_exception": "Retain original subclaim D and absent score, status and axes without inheriting parent C50 or axes. Null overall findings do not establish a precise absence of effect, equivalence or null findings at every site, and a small age subgroup is not extended into an overall effect. Falls, fractures and BMD, and female fallers versus BMD age subgroups, are distinguished. No erratum details, effects, CIs, P values, denominators, unique counts, independence or safety certification, or new exercise, prevention or treatment methods are created.",
      "criterion": "Original material and analysis scope for Original claim, grade and explanation for increased overall hip BMD must be linked to populations, comparators, measurement sites, denominators, overall and subgroup findings and timing for the selected BMD question, distinguishing stored summaries, unverified details and other outcomes.",
      "basis": "Preserved application conditions concerning questions, comparisons, reports versus trials, outcomes, denominators, errata and harms were referenced.",
      "condition_origin": "These are in-house application conditions preserved for the existing subclaim. They do not establish clinical preregistration, official-tool certification or completed content review.",
      "proposed_research": "Material needed: Original measurement sites, analysis populations, arm values and changes, denominators, effects, CIs and plans are needed. An existing subclaim is transferred without creating new claims, grades or independence certification. This records needed materials; no new research was executed."
    },
    {
      "item_id": "N02",
      "question_type": "Evidence condition",
      "question": "Who participated in the direct BMD trial, and how many?",
      "needed": "Sakai 2010; 94 postmenopausal women; 49 versus 45",
      "role": "Required",
      "role_reason": "This condition connects Sakai 2010; 94 postmenopausal women; 49 versus 45 with populations, comparators, measurement sites, ROIs, overall and subgroup findings, denominators, timing, prespecification, precision, reports, errata and harms for the selected overall-hip-BMD question.",
      "application_exception": "Retain original subclaim D and absent score, status and axes without inheriting parent C50 or axes. Null overall findings do not establish a precise absence of effect, equivalence or null findings at every site, and a small age subgroup is not extended into an overall effect. Falls, fractures and BMD, and female fallers versus BMD age subgroups, are distinguished. No erratum details, effects, CIs, P values, denominators, unique counts, independence or safety certification, or new exercise, prevention or treatment methods are created.",
      "criterion": "Original material and analysis scope for Sakai 2010; 94 postmenopausal women; 49 versus 45 must be linked to populations, comparators, measurement sites, denominators, overall and subgroup findings and timing for the selected BMD question, distinguishing stored summaries, unverified details and other outcomes.",
      "basis": "Preserved application conditions concerning questions, comparisons, reports versus trials, outcomes, denominators, errata and harms were referenced.",
      "condition_origin": "These are in-house application conditions preserved for the existing subclaim. They do not establish clinical preregistration, official-tool certification or completed content review.",
      "proposed_research": "Material needed: Diagnosis, baseline BMD, bone disease, age, medications, eligibility and exclusions, and arm-specific allocation, analysis and missingness are needed. The total of 94 is not used as a completion denominator for every BMD outcome. This records needed materials; no new research was executed."
    },
    {
      "item_id": "N03",
      "question_type": "Evidence condition",
      "question": "What are the arm values, direct effects and CIs behind null overall BMD?",
      "needed": "Gaps in 6-month overall findings and direct between-group estimates",
      "role": "Required",
      "role_reason": "This condition connects Gaps in 6-month overall findings and direct between-group estimates with populations, comparators, measurement sites, ROIs, overall and subgroup findings, denominators, timing, prespecification, precision, reports, errata and harms for the selected overall-hip-BMD question.",
      "application_exception": "Retain original subclaim D and absent score, status and axes without inheriting parent C50 or axes. Null overall findings do not establish a precise absence of effect, equivalence or null findings at every site, and a small age subgroup is not extended into an overall effect. Falls, fractures and BMD, and female fallers versus BMD age subgroups, are distinguished. No erratum details, effects, CIs, P values, denominators, unique counts, independence or safety certification, or new exercise, prevention or treatment methods are created.",
      "criterion": "Original material and analysis scope for Gaps in 6-month overall findings and direct between-group estimates must be linked to populations, comparators, measurement sites, denominators, overall and subgroup findings and timing for the selected BMD question, distinguishing stored summaries, unverified details and other outcomes.",
      "basis": "Preserved application conditions concerning questions, comparisons, reports versus trials, outcomes, denominators, errata and harms were referenced.",
      "condition_origin": "These are in-house application conditions preserved for the existing subclaim. They do not establish clinical preregistration, official-tool certification or completed content review.",
      "proposed_research": "Material needed: Original BMD result tables, units, comparators and analyses, arm denominators, direct effects, CIs and P values are needed. No new changes, proportions or intervals are calculated. This records needed materials; no new research was executed."
    },
    {
      "item_id": "N04",
      "question_type": "Evidence condition",
      "question": "Are overall findings distinguished from exact hip measurement sites?",
      "needed": "Overall findings and anatomical hip BMD sites, ROIs and equipment",
      "role": "Required",
      "role_reason": "This condition connects Overall findings and anatomical hip BMD sites, ROIs and equipment with populations, comparators, measurement sites, ROIs, overall and subgroup findings, denominators, timing, prespecification, precision, reports, errata and harms for the selected overall-hip-BMD question.",
      "application_exception": "Retain original subclaim D and absent score, status and axes without inheriting parent C50 or axes. Null overall findings do not establish a precise absence of effect, equivalence or null findings at every site, and a small age subgroup is not extended into an overall effect. Falls, fractures and BMD, and female fallers versus BMD age subgroups, are distinguished. No erratum details, effects, CIs, P values, denominators, unique counts, independence or safety certification, or new exercise, prevention or treatment methods are created.",
      "criterion": "Original material and analysis scope for Overall findings and anatomical hip BMD sites, ROIs and equipment must be linked to populations, comparators, measurement sites, denominators, overall and subgroup findings and timing for the selected BMD question, distinguishing stored summaries, unverified details and other outcomes.",
      "basis": "Preserved application conditions concerning questions, comparisons, reports versus trials, outcomes, denominators, errata and harms were referenced.",
      "condition_origin": "These are in-house application conditions preserved for the existing subclaim. They do not establish clinical preregistration, official-tool certification or completed content review.",
      "proposed_research": "Material needed: Original measurement sites, ROIs, equipment, analysis populations, site-specific findings, denominators and CIs are needed. Site names or numbers absent from the summary are not invented. This records needed materials; no new research was executed."
    },
    {
      "item_id": "N05",
      "question_type": "Evidence condition",
      "question": "Is the small subgroup signal in people aged at least 70 extended to the whole population?",
      "needed": "Site-specific age-subgroup signals and null overall findings",
      "role": "Required",
      "role_reason": "This condition connects Site-specific age-subgroup signals and null overall findings with populations, comparators, measurement sites, ROIs, overall and subgroup findings, denominators, timing, prespecification, precision, reports, errata and harms for the selected overall-hip-BMD question.",
      "application_exception": "Retain original subclaim D and absent score, status and axes without inheriting parent C50 or axes. Null overall findings do not establish a precise absence of effect, equivalence or null findings at every site, and a small age subgroup is not extended into an overall effect. Falls, fractures and BMD, and female fallers versus BMD age subgroups, are distinguished. No erratum details, effects, CIs, P values, denominators, unique counts, independence or safety certification, or new exercise, prevention or treatment methods are created.",
      "criterion": "Original material and analysis scope for Site-specific age-subgroup signals and null overall findings must be linked to populations, comparators, measurement sites, denominators, overall and subgroup findings and timing for the selected BMD question, distinguishing stored summaries, unverified details and other outcomes.",
      "basis": "Preserved application conditions concerning questions, comparisons, reports versus trials, outcomes, denominators, errata and harms were referenced.",
      "condition_origin": "These are in-house application conditions preserved for the existing subclaim. They do not establish clinical preregistration, official-tool certification or completed content review.",
      "proposed_research": "Material needed: Age-subgroup denominators, sites, timing, original values, CIs, prespecification, interactions and multiple-comparison methods are needed. Subgroup populations or effects are not invented. This records needed materials; no new research was executed."
    },
    {
      "item_id": "N06",
      "question_type": "Evidence condition",
      "question": "Were positive subgroup and site findings prespecified confirmation?",
      "needed": "Prespecified age boundaries, site and time hierarchies, and multiple selection",
      "role": "Required",
      "role_reason": "This condition connects Prespecified age boundaries, site and time hierarchies, and multiple selection with populations, comparators, measurement sites, ROIs, overall and subgroup findings, denominators, timing, prespecification, precision, reports, errata and harms for the selected overall-hip-BMD question.",
      "application_exception": "Retain original subclaim D and absent score, status and axes without inheriting parent C50 or axes. Null overall findings do not establish a precise absence of effect, equivalence or null findings at every site, and a small age subgroup is not extended into an overall effect. Falls, fractures and BMD, and female fallers versus BMD age subgroups, are distinguished. No erratum details, effects, CIs, P values, denominators, unique counts, independence or safety certification, or new exercise, prevention or treatment methods are created.",
      "criterion": "Original material and analysis scope for Prespecified age boundaries, site and time hierarchies, and multiple selection must be linked to populations, comparators, measurement sites, denominators, overall and subgroup findings and timing for the selected BMD question, distinguishing stored summaries, unverified details and other outcomes.",
      "basis": "Preserved application conditions concerning questions, comparisons, reports versus trials, outcomes, denominators, errata and harms were referenced.",
      "condition_origin": "These are in-house application conditions preserved for the existing subclaim. They do not establish clinical preregistration, official-tool certification or completed content review.",
      "proposed_research": "Material needed: Registration, protocols, analysis plans, prespecified subgroups, sites, timing, success rules, interactions and complete result tables are needed. Prespecification or official-tool review was not verified in this work. This records needed materials; no new research was executed."
    },
    {
      "item_id": "N07",
      "question_type": "Evidence condition",
      "question": "Do null overall findings prove that even small benefits are absent?",
      "needed": "Gaps in precision and clinical importance around null BMD findings",
      "role": "Required",
      "role_reason": "This condition connects Gaps in precision and clinical importance around null BMD findings with populations, comparators, measurement sites, ROIs, overall and subgroup findings, denominators, timing, prespecification, precision, reports, errata and harms for the selected overall-hip-BMD question.",
      "application_exception": "Retain original subclaim D and absent score, status and axes without inheriting parent C50 or axes. Null overall findings do not establish a precise absence of effect, equivalence or null findings at every site, and a small age subgroup is not extended into an overall effect. Falls, fractures and BMD, and female fallers versus BMD age subgroups, are distinguished. No erratum details, effects, CIs, P values, denominators, unique counts, independence or safety certification, or new exercise, prevention or treatment methods are created.",
      "criterion": "Original material and analysis scope for Gaps in precision and clinical importance around null BMD findings must be linked to populations, comparators, measurement sites, denominators, overall and subgroup findings and timing for the selected BMD question, distinguishing stored summaries, unverified details and other outcomes.",
      "basis": "Preserved application conditions concerning questions, comparisons, reports versus trials, outcomes, denominators, errata and harms were referenced.",
      "condition_origin": "These are in-house application conditions preserved for the existing subclaim. They do not establish clinical preregistration, official-tool certification or completed content review.",
      "proposed_research": "Material needed: Original effects, CIs, clinical-importance boundaries, measurement error, power and denominators are needed. No new subclaim grades, effects or CIs are calculated. This records needed materials; no new research was executed."
    },
    {
      "item_id": "N08",
      "question_type": "Evidence condition",
      "question": "Are BMD changes direct hip-fracture prevention outcomes?",
      "needed": "Distinguishing the BMD surrogate from fracture events",
      "role": "Required",
      "role_reason": "This condition connects Distinguishing the BMD surrogate from fracture events with populations, comparators, measurement sites, ROIs, overall and subgroup findings, denominators, timing, prespecification, precision, reports, errata and harms for the selected overall-hip-BMD question.",
      "application_exception": "Retain original subclaim D and absent score, status and axes without inheriting parent C50 or axes. Null overall findings do not establish a precise absence of effect, equivalence or null findings at every site, and a small age subgroup is not extended into an overall effect. Falls, fractures and BMD, and female fallers versus BMD age subgroups, are distinguished. No erratum details, effects, CIs, P values, denominators, unique counts, independence or safety certification, or new exercise, prevention or treatment methods are created.",
      "criterion": "Original material and analysis scope for Distinguishing the BMD surrogate from fracture events must be linked to populations, comparators, measurement sites, denominators, overall and subgroup findings and timing for the selected BMD question, distinguishing stored summaries, unverified details and other outcomes.",
      "basis": "Preserved application conditions concerning questions, comparisons, reports versus trials, outcomes, denominators, errata and harms were referenced.",
      "condition_origin": "These are in-house application conditions preserved for the existing subclaim. They do not establish clinical preregistration, official-tool certification or completed content review.",
      "proposed_research": "Material needed: Fracture events, exposure, denominators, clinical effects, CIs and material connecting BMD changes with importance are needed. BMD values are not converted into fracture risks. This records needed materials; no new research was executed."
    },
    {
      "item_id": "N09",
      "question_type": "Evidence condition",
      "question": "Does the signal of 118 versus 121 falls mean increased BMD?",
      "needed": "Directness of cumulative falls, fractures and BMD",
      "role": "Required",
      "role_reason": "This condition connects Directness of cumulative falls, fractures and BMD with populations, comparators, measurement sites, ROIs, overall and subgroup findings, denominators, timing, prespecification, precision, reports, errata and harms for the selected overall-hip-BMD question.",
      "application_exception": "Retain original subclaim D and absent score, status and axes without inheriting parent C50 or axes. Null overall findings do not establish a precise absence of effect, equivalence or null findings at every site, and a small age subgroup is not extended into an overall effect. Falls, fractures and BMD, and female fallers versus BMD age subgroups, are distinguished. No erratum details, effects, CIs, P values, denominators, unique counts, independence or safety certification, or new exercise, prevention or treatment methods are created.",
      "criterion": "Original material and analysis scope for Directness of cumulative falls, fractures and BMD must be linked to populations, comparators, measurement sites, denominators, overall and subgroup findings and timing for the selected BMD question, distinguishing stored summaries, unverified details and other outcomes.",
      "basis": "Preserved application conditions concerning questions, comparisons, reports versus trials, outcomes, denominators, errata and harms were referenced.",
      "condition_origin": "These are in-house application conditions preserved for the existing subclaim. They do not establish clinical preregistration, official-tool certification or completed content review.",
      "proposed_research": "Material needed: Original arm values, denominators, estimates, CIs, exposure and timing for each trial and outcome are needed. No new faller proportions, risks or BMD effects are calculated. This records needed materials; no new research was executed."
    },
    {
      "item_id": "N10",
      "question_type": "Evidence condition",
      "question": "Are later female-faller signals the same as the BMD age subgroup?",
      "needed": "Female and age subgroups with distinct outcomes",
      "role": "Required",
      "role_reason": "This condition connects Female and age subgroups with distinct outcomes with populations, comparators, measurement sites, ROIs, overall and subgroup findings, denominators, timing, prespecification, precision, reports, errata and harms for the selected overall-hip-BMD question.",
      "application_exception": "Retain original subclaim D and absent score, status and axes without inheriting parent C50 or axes. Null overall findings do not establish a precise absence of effect, equivalence or null findings at every site, and a small age subgroup is not extended into an overall effect. Falls, fractures and BMD, and female fallers versus BMD age subgroups, are distinguished. No erratum details, effects, CIs, P values, denominators, unique counts, independence or safety certification, or new exercise, prevention or treatment methods are created.",
      "criterion": "Original material and analysis scope for Female and age subgroups with distinct outcomes must be linked to populations, comparators, measurement sites, denominators, overall and subgroup findings and timing for the selected BMD question, distinguishing stored summaries, unverified details and other outcomes.",
      "basis": "Preserved application conditions concerning questions, comparisons, reports versus trials, outcomes, denominators, errata and harms were referenced.",
      "condition_origin": "These are in-house application conditions preserved for the existing subclaim. They do not establish clinical preregistration, official-tool certification or completed content review.",
      "proposed_research": "Material needed: Population, prespecification, denominators, outcomes, timing, effects, CIs and report relationships for each subgroup analysis are needed. This records needed materials; no new research was executed."
    },
    {
      "item_id": "N11",
      "question_type": "Evidence condition",
      "question": "Does a historical description as an independent BMD trial certify independence now?",
      "needed": "Sakai and Sakamoto research groups, support and recruitment relationships",
      "role": "Required",
      "role_reason": "This condition connects Sakai and Sakamoto research groups, support and recruitment relationships with populations, comparators, measurement sites, ROIs, overall and subgroup findings, denominators, timing, prespecification, precision, reports, errata and harms for the selected overall-hip-BMD question.",
      "application_exception": "Retain original subclaim D and absent score, status and axes without inheriting parent C50 or axes. Null overall findings do not establish a precise absence of effect, equivalence or null findings at every site, and a small age subgroup is not extended into an overall effect. Falls, fractures and BMD, and female fallers versus BMD age subgroups, are distinguished. No erratum details, effects, CIs, P values, denominators, unique counts, independence or safety certification, or new exercise, prevention or treatment methods are created.",
      "criterion": "Original material and analysis scope for Sakai and Sakamoto research groups, support and recruitment relationships must be linked to populations, comparators, measurement sites, denominators, overall and subgroup findings and timing for the selected BMD question, distinguishing stored summaries, unverified details and other outcomes.",
      "basis": "Preserved application conditions concerning questions, comparisons, reports versus trials, outcomes, denominators, errata and harms were referenced.",
      "condition_origin": "These are in-house application conditions preserved for the existing subclaim. They do not establish clinical preregistration, official-tool certification or completed content review.",
      "proposed_research": "Material needed: Institutions, support, recruitment, participants, registration, report overlap and original methods and results are needed. Unique trial and participant totals remain unverified. This records needed materials; no new research was executed."
    },
    {
      "item_id": "N12",
      "question_type": "Evidence condition",
      "question": "Are 6-month measurements extended to long-term or post-discontinuation effects?",
      "needed": "Boundaries between 6-month BMD, long-term effects, maintenance and other sites",
      "role": "Required",
      "role_reason": "This condition connects Boundaries between 6-month BMD, long-term effects, maintenance and other sites with populations, comparators, measurement sites, ROIs, overall and subgroup findings, denominators, timing, prespecification, precision, reports, errata and harms for the selected overall-hip-BMD question.",
      "application_exception": "Retain original subclaim D and absent score, status and axes without inheriting parent C50 or axes. Null overall findings do not establish a precise absence of effect, equivalence or null findings at every site, and a small age subgroup is not extended into an overall effect. Falls, fractures and BMD, and female fallers versus BMD age subgroups, are distinguished. No erratum details, effects, CIs, P values, denominators, unique counts, independence or safety certification, or new exercise, prevention or treatment methods are created.",
      "criterion": "Original material and analysis scope for Boundaries between 6-month BMD, long-term effects, maintenance and other sites must be linked to populations, comparators, measurement sites, denominators, overall and subgroup findings and timing for the selected BMD question, distinguishing stored summaries, unverified details and other outcomes.",
      "basis": "Preserved application conditions concerning questions, comparisons, reports versus trials, outcomes, denominators, errata and harms were referenced.",
      "condition_origin": "These are in-house application conditions preserved for the existing subclaim. They do not establish clinical preregistration, official-tool certification or completed content review.",
      "proposed_research": "Material needed: Measurement and follow-up periods, post-discontinuation exercise, treatment, adherence, site-specific original values, denominators, effects and CIs are needed. This records needed materials; no new research was executed."
    },
    {
      "item_id": "N13",
      "question_type": "Evidence condition",
      "question": "Were measurement, allocation, baseline imbalance and missingness verified?",
      "needed": "BMD equipment, precision, blinding, baseline adjustment and denominators",
      "role": "Required",
      "role_reason": "This condition connects BMD equipment, precision, blinding, baseline adjustment and denominators with populations, comparators, measurement sites, ROIs, overall and subgroup findings, denominators, timing, prespecification, precision, reports, errata and harms for the selected overall-hip-BMD question.",
      "application_exception": "Retain original subclaim D and absent score, status and axes without inheriting parent C50 or axes. Null overall findings do not establish a precise absence of effect, equivalence or null findings at every site, and a small age subgroup is not extended into an overall effect. Falls, fractures and BMD, and female fallers versus BMD age subgroups, are distinguished. No erratum details, effects, CIs, P values, denominators, unique counts, independence or safety certification, or new exercise, prevention or treatment methods are created.",
      "criterion": "Original material and analysis scope for BMD equipment, precision, blinding, baseline adjustment and denominators must be linked to populations, comparators, measurement sites, denominators, overall and subgroup findings and timing for the selected BMD question, distinguishing stored summaries, unverified details and other outcomes.",
      "basis": "Preserved application conditions concerning questions, comparisons, reports versus trials, outcomes, denominators, errata and harms were referenced.",
      "condition_origin": "These are in-house application conditions preserved for the existing subclaim. They do not establish clinical preregistration, official-tool certification or completed content review.",
      "proposed_research": "Material needed: Original equipment, ROIs, measurement consistency, allocation, concealment, baseline and analysis adjustment, missingness, withdrawals and prespecified plans are needed. No official risk-of-bias assessment or regrading was performed. This records needed materials; no new research was executed."
    },
    {
      "item_id": "N14",
      "question_type": "Evidence condition",
      "question": "How are the stand-alone intervention, control and concurrent bone treatments attributed?",
      "needed": "Exercise exposure, comparators, bone treatment, supplementation and adherence",
      "role": "Required",
      "role_reason": "This condition connects Exercise exposure, comparators, bone treatment, supplementation and adherence with populations, comparators, measurement sites, ROIs, overall and subgroup findings, denominators, timing, prespecification, precision, reports, errata and harms for the selected overall-hip-BMD question.",
      "application_exception": "Retain original subclaim D and absent score, status and axes without inheriting parent C50 or axes. Null overall findings do not establish a precise absence of effect, equivalence or null findings at every site, and a small age subgroup is not extended into an overall effect. Falls, fractures and BMD, and female fallers versus BMD age subgroups, are distinguished. No erratum details, effects, CIs, P values, denominators, unique counts, independence or safety certification, or new exercise, prevention or treatment methods are created.",
      "criterion": "Original material and analysis scope for Exercise exposure, comparators, bone treatment, supplementation and adherence must be linked to populations, comparators, measurement sites, denominators, overall and subgroup findings and timing for the selected BMD question, distinguishing stored summaries, unverified details and other outcomes.",
      "basis": "Preserved application conditions concerning questions, comparisons, reports versus trials, outcomes, denominators, errata and harms were referenced.",
      "condition_origin": "These are in-house application conditions preserved for the existing subclaim. They do not establish clinical preregistration, official-tool certification or completed content review.",
      "proposed_research": "Material needed: Sakai's original exercise, controls, concurrent bone treatment and medications, exposure, participation, denominators and timing are needed. No new exercise or treatment methods are provided. This records needed materials; no new research was executed."
    },
    {
      "item_id": "N15",
      "question_type": "Evidence condition",
      "question": "Is multicomponent balance-and-strength exercise reassigned as a stand-alone BMD effect?",
      "needed": "Distinguishing the stand-alone intervention from the broader program in verdict 1557",
      "role": "Required",
      "role_reason": "This condition connects Distinguishing the stand-alone intervention from the broader program in verdict 1557 with populations, comparators, measurement sites, ROIs, overall and subgroup findings, denominators, timing, prespecification, precision, reports, errata and harms for the selected overall-hip-BMD question.",
      "application_exception": "Retain original subclaim D and absent score, status and axes without inheriting parent C50 or axes. Null overall findings do not establish a precise absence of effect, equivalence or null findings at every site, and a small age subgroup is not extended into an overall effect. Falls, fractures and BMD, and female fallers versus BMD age subgroups, are distinguished. No erratum details, effects, CIs, P values, denominators, unique counts, independence or safety certification, or new exercise, prevention or treatment methods are created.",
      "criterion": "Original material and analysis scope for Distinguishing the stand-alone intervention from the broader program in verdict 1557 must be linked to populations, comparators, measurement sites, denominators, overall and subgroup findings and timing for the selected BMD question, distinguishing stored summaries, unverified details and other outcomes.",
      "basis": "Preserved application conditions concerning questions, comparisons, reports versus trials, outcomes, denominators, errata and harms were referenced.",
      "condition_origin": "These are in-house application conditions preserved for the existing subclaim. They do not establish clinical preregistration, official-tool certification or completed content review.",
      "proposed_research": "Material needed: Direct material for the same stand-alone intervention, population, control and prespecified BMD sites and timing is needed. No new reading or lookup of verdict 1557 materials or practice instructions was performed. This records needed materials; no new research was executed."
    },
    {
      "item_id": "N16",
      "question_type": "Evidence condition",
      "question": "Are a literature erratum and the parent's empty correction history distinguished?",
      "needed": "Erratum to the 2013 trial, target report and parent correction history",
      "role": "Required",
      "role_reason": "This condition connects Erratum to the 2013 trial, target report and parent correction history with populations, comparators, measurement sites, ROIs, overall and subgroup findings, denominators, timing, prespecification, precision, reports, errata and harms for the selected overall-hip-BMD question.",
      "application_exception": "Retain original subclaim D and absent score, status and axes without inheriting parent C50 or axes. Null overall findings do not establish a precise absence of effect, equivalence or null findings at every site, and a small age subgroup is not extended into an overall effect. Falls, fractures and BMD, and female fallers versus BMD age subgroups, are distinguished. No erratum details, effects, CIs, P values, denominators, unique counts, independence or safety certification, or new exercise, prevention or treatment methods are created.",
      "criterion": "Original material and analysis scope for Erratum to the 2013 trial, target report and parent correction history must be linked to populations, comparators, measurement sites, denominators, overall and subgroup findings and timing for the selected BMD question, distinguishing stored summaries, unverified details and other outcomes.",
      "basis": "Preserved application conditions concerning questions, comparisons, reports versus trials, outcomes, denominators, errata and harms were referenced.",
      "condition_origin": "These are in-house application conditions preserved for the existing subclaim. They do not establish clinical preregistration, official-tool certification or completed content review.",
      "proposed_research": "Material needed: The complete erratum, original and corrected values, target reports, outcomes and effects are needed. An erratum is a separate report and is not counted as a new randomized trial. This records needed materials; no new research was executed."
    },
    {
      "item_id": "N17",
      "question_type": "Evidence condition",
      "question": "Are original research conditions turned into new exercise or fracture-prevention instructions?",
      "needed": "Boundaries between preserved intervention conditions and personal practice instructions",
      "role": "Supplementary",
      "role_reason": "This condition connects Boundaries between preserved intervention conditions and personal practice instructions with populations, comparators, measurement sites, ROIs, overall and subgroup findings, denominators, timing, prespecification, precision, reports, errata and harms for the selected overall-hip-BMD question.",
      "application_exception": "Retain original subclaim D and absent score, status and axes without inheriting parent C50 or axes. Null overall findings do not establish a precise absence of effect, equivalence or null findings at every site, and a small age subgroup is not extended into an overall effect. Falls, fractures and BMD, and female fallers versus BMD age subgroups, are distinguished. No erratum details, effects, CIs, P values, denominators, unique counts, independence or safety certification, or new exercise, prevention or treatment methods are created.",
      "criterion": "Original material and analysis scope for Boundaries between preserved intervention conditions and personal practice instructions must be linked to populations, comparators, measurement sites, denominators, overall and subgroup findings and timing for the selected BMD question, distinguishing stored summaries, unverified details and other outcomes.",
      "basis": "Preserved application conditions concerning questions, comparisons, reports versus trials, outcomes, denominators, errata and harms were referenced.",
      "condition_origin": "These are in-house application conditions preserved for the existing subclaim. They do not establish clinical preregistration, official-tool certification or completed content review.",
      "proposed_research": "Material needed: Actual exercise and treatment decisions are a separate scope. Original methods, populations, controls, exposure and adherence materials must be acquired and reviewed. This records needed materials; no new research was executed."
    },
    {
      "item_id": "N18",
      "question_type": "Evidence condition",
      "question": "Are company funding, products, authors and design or analysis roles distinguished?",
      "needed": "Report-specific company-involvement categories and independence",
      "role": "Required",
      "role_reason": "This condition connects Report-specific company-involvement categories and independence with populations, comparators, measurement sites, ROIs, overall and subgroup findings, denominators, timing, prespecification, precision, reports, errata and harms for the selected overall-hip-BMD question.",
      "application_exception": "Retain original subclaim D and absent score, status and axes without inheriting parent C50 or axes. Null overall findings do not establish a precise absence of effect, equivalence or null findings at every site, and a small age subgroup is not extended into an overall effect. Falls, fractures and BMD, and female fallers versus BMD age subgroups, are distinguished. No erratum details, effects, CIs, P values, denominators, unique counts, independence or safety certification, or new exercise, prevention or treatment methods are created.",
      "criterion": "Original material and analysis scope for Report-specific company-involvement categories and independence must be linked to populations, comparators, measurement sites, denominators, overall and subgroup findings and timing for the selected BMD question, distinguishing stored summaries, unverified details and other outcomes.",
      "basis": "Preserved application conditions concerning questions, comparisons, reports versus trials, outcomes, denominators, errata and harms were referenced.",
      "condition_origin": "These are in-house application conditions preserved for the existing subclaim. They do not establish clinical preregistration, official-tool certification or completed content review.",
      "proposed_research": "Material needed: Documents are needed for money, product and equipment support, company and author affiliations, design, analysis and publication roles, and supporter identities separately. This records needed materials; no new research was executed."
    },
    {
      "item_id": "N19",
      "question_type": "Evidence condition",
      "question": "Are reports, errata and shared populations summed as independent trials?",
      "needed": "Report, trial and participant relationships for 3 papers and 1 erratum",
      "role": "Required",
      "role_reason": "This condition connects Report, trial and participant relationships for 3 papers and 1 erratum with populations, comparators, measurement sites, ROIs, overall and subgroup findings, denominators, timing, prespecification, precision, reports, errata and harms for the selected overall-hip-BMD question.",
      "application_exception": "Retain original subclaim D and absent score, status and axes without inheriting parent C50 or axes. Null overall findings do not establish a precise absence of effect, equivalence or null findings at every site, and a small age subgroup is not extended into an overall effect. Falls, fractures and BMD, and female fallers versus BMD age subgroups, are distinguished. No erratum details, effects, CIs, P values, denominators, unique counts, independence or safety certification, or new exercise, prevention or treatment methods are created.",
      "criterion": "Original material and analysis scope for Report, trial and participant relationships for 3 papers and 1 erratum must be linked to populations, comparators, measurement sites, denominators, overall and subgroup findings and timing for the selected BMD question, distinguishing stored summaries, unverified details and other outcomes.",
      "basis": "Preserved application conditions concerning questions, comparisons, reports versus trials, outcomes, denominators, errata and harms were referenced.",
      "condition_origin": "These are in-house application conditions preserved for the existing subclaim. They do not establish clinical preregistration, official-tool certification or completed content review.",
      "proposed_research": "Material needed: Material linking reports, trials, erratum versions, registration, institutions, recruitment and participants is needed. Unique trial and participant counts remain unverified. This records needed materials; no new research was executed."
    },
    {
      "item_id": "N20",
      "question_type": "Evidence condition",
      "question": "Were original registration and prespecified plans actually read?",
      "needed": "Reading levels for registration, protocols, analysis plans, changes and denominators",
      "role": "Required",
      "role_reason": "This condition connects Reading levels for registration, protocols, analysis plans, changes and denominators with populations, comparators, measurement sites, ROIs, overall and subgroup findings, denominators, timing, prespecification, precision, reports, errata and harms for the selected overall-hip-BMD question.",
      "application_exception": "Retain original subclaim D and absent score, status and axes without inheriting parent C50 or axes. Null overall findings do not establish a precise absence of effect, equivalence or null findings at every site, and a small age subgroup is not extended into an overall effect. Falls, fractures and BMD, and female fallers versus BMD age subgroups, are distinguished. No erratum details, effects, CIs, P values, denominators, unique counts, independence or safety certification, or new exercise, prevention or treatment methods are created.",
      "criterion": "Original material and analysis scope for Reading levels for registration, protocols, analysis plans, changes and denominators must be linked to populations, comparators, measurement sites, denominators, overall and subgroup findings and timing for the selected BMD question, distinguishing stored summaries, unverified details and other outcomes.",
      "basis": "Preserved application conditions concerning questions, comparisons, reports versus trials, outcomes, denominators, errata and harms were referenced.",
      "condition_origin": "These are in-house application conditions preserved for the existing subclaim. They do not establish clinical preregistration, official-tool certification or completed content review.",
      "proposed_research": "Material needed: Original registration, protocols, analysis plans, changes, exclusions, subgroups, outcomes and denominator materials are needed. No external lookup or access test was performed. This records needed materials; no new research was executed."
    },
    {
      "item_id": "N21",
      "question_type": "Evidence condition",
      "question": "Were details on harms, vulnerable populations, exposure and denominators acquired?",
      "needed": "Falls or injuries during exercise, support, supervision and harm collection",
      "role": "Supplementary",
      "role_reason": "This condition connects Falls or injuries during exercise, support, supervision and harm collection with populations, comparators, measurement sites, ROIs, overall and subgroup findings, denominators, timing, prespecification, precision, reports, errata and harms for the selected overall-hip-BMD question.",
      "application_exception": "Retain original subclaim D and absent score, status and axes without inheriting parent C50 or axes. Null overall findings do not establish a precise absence of effect, equivalence or null findings at every site, and a small age subgroup is not extended into an overall effect. Falls, fractures and BMD, and female fallers versus BMD age subgroups, are distinguished. No erratum details, effects, CIs, P values, denominators, unique counts, independence or safety certification, or new exercise, prevention or treatment methods are created.",
      "criterion": "Original material and analysis scope for Falls or injuries during exercise, support, supervision and harm collection must be linked to populations, comparators, measurement sites, denominators, overall and subgroup findings and timing for the selected BMD question, distinguishing stored summaries, unverified details and other outcomes.",
      "basis": "Preserved application conditions concerning questions, comparisons, reports versus trials, outcomes, denominators, errata and harms were referenced.",
      "condition_origin": "These are in-house application conditions preserved for the existing subclaim. They do not establish clinical preregistration, official-tool certification or completed content review.",
      "proposed_research": "Material needed: Active harm collection, timing, severity, falls, injuries, discontinuation, concurrent treatment, arm denominators, exposure, support, supervision, vulnerable populations and long-term material are needed. No new exercise or treatment recommendations are created. This records needed materials; no new research was executed."
    },
    {
      "item_id": "N22",
      "question_type": "Evidence condition",
      "question": "How do subclaim D and parent C50, axes and unrecorded precision differ?",
      "needed": "Original subclaim grade, absent score, status and axes, and parent context",
      "role": "Required",
      "role_reason": "This condition connects Original subclaim grade, absent score, status and axes, and parent context with populations, comparators, measurement sites, ROIs, overall and subgroup findings, denominators, timing, prespecification, precision, reports, errata and harms for the selected overall-hip-BMD question.",
      "application_exception": "Retain original subclaim D and absent score, status and axes without inheriting parent C50 or axes. Null overall findings do not establish a precise absence of effect, equivalence or null findings at every site, and a small age subgroup is not extended into an overall effect. Falls, fractures and BMD, and female fallers versus BMD age subgroups, are distinguished. No erratum details, effects, CIs, P values, denominators, unique counts, independence or safety certification, or new exercise, prevention or treatment methods are created.",
      "criterion": "Original material and analysis scope for Original subclaim grade, absent score, status and axes, and parent context must be linked to populations, comparators, measurement sites, denominators, overall and subgroup findings and timing for the selected BMD question, distinguishing stored summaries, unverified details and other outcomes.",
      "basis": "Preserved application conditions concerning questions, comparisons, reports versus trials, outcomes, denominators, errata and harms were referenced.",
      "condition_origin": "These are in-house application conditions preserved for the existing subclaim. They do not establish clinical preregistration, official-tool certification or completed content review.",
      "proposed_research": "Material needed: The application boundary between parent and subclaims needs content review. Unrecorded values are not replaced by defaults, and no new grades, scores or independence certification are created. This records needed materials; no new research was executed."
    },
    {
      "item_id": "N23",
      "question_type": "Evidence condition",
      "question": "How does reading a stored summary differ from reading external originals or an erratum?",
      "needed": "Distinguishing summaries, abstracts, full texts, registration, plans and errata",
      "role": "Required",
      "role_reason": "This condition connects Distinguishing summaries, abstracts, full texts, registration, plans and errata with populations, comparators, measurement sites, ROIs, overall and subgroup findings, denominators, timing, prespecification, precision, reports, errata and harms for the selected overall-hip-BMD question.",
      "application_exception": "Retain original subclaim D and absent score, status and axes without inheriting parent C50 or axes. Null overall findings do not establish a precise absence of effect, equivalence or null findings at every site, and a small age subgroup is not extended into an overall effect. Falls, fractures and BMD, and female fallers versus BMD age subgroups, are distinguished. No erratum details, effects, CIs, P values, denominators, unique counts, independence or safety certification, or new exercise, prevention or treatment methods are created.",
      "criterion": "Original material and analysis scope for Distinguishing summaries, abstracts, full texts, registration, plans and errata must be linked to populations, comparators, measurement sites, denominators, overall and subgroup findings and timing for the selected BMD question, distinguishing stored summaries, unverified details and other outcomes.",
      "basis": "Preserved application conditions concerning questions, comparisons, reports versus trials, outcomes, denominators, errata and harms were referenced.",
      "condition_origin": "These are in-house application conditions preserved for the existing subclaim. They do not establish clinical preregistration, official-tool certification or completed content review.",
      "proposed_research": "Material needed: Acquisition, reading and content review of external materials require separate records. A URL does not establish reading, accessibility or completed review. This records needed materials; no new research was executed."
    },
    {
      "item_id": "N24",
      "question_type": "Evidence condition",
      "question": "Are representative populations, periods or language values copied to other reports?",
      "needed": "Preserving parent Korean and English content, populations, timing and denominators",
      "role": "Required",
      "role_reason": "This condition connects Preserving parent Korean and English content, populations, timing and denominators with populations, comparators, measurement sites, ROIs, overall and subgroup findings, denominators, timing, prespecification, precision, reports, errata and harms for the selected overall-hip-BMD question.",
      "application_exception": "Retain original subclaim D and absent score, status and axes without inheriting parent C50 or axes. Null overall findings do not establish a precise absence of effect, equivalence or null findings at every site, and a small age subgroup is not extended into an overall effect. Falls, fractures and BMD, and female fallers versus BMD age subgroups, are distinguished. No erratum details, effects, CIs, P values, denominators, unique counts, independence or safety certification, or new exercise, prevention or treatment methods are created.",
      "criterion": "Original material and analysis scope for Preserving parent Korean and English content, populations, timing and denominators must be linked to populations, comparators, measurement sites, denominators, overall and subgroup findings and timing for the selected BMD question, distinguishing stored summaries, unverified details and other outcomes.",
      "basis": "Preserved application conditions concerning questions, comparisons, reports versus trials, outcomes, denominators, errata and harms were referenced.",
      "condition_origin": "These are in-house application conditions preserved for the existing subclaim. They do not establish clinical preregistration, official-tool certification or completed content review.",
      "proposed_research": "Material needed: Original populations, interventions, controls, denominators, outcomes, timing and English content for each report are needed for comparison. No new external English comparison or erratum-content review was performed. This records needed materials; no new research was executed."
    },
    {
      "item_id": "N25",
      "question_type": "Evidence condition",
      "question": "Are original evidence dates, empty correction history and production dates distinguished?",
      "needed": "Preserving the original cut-off, correction and deliberation histories, and original URL",
      "role": "Required",
      "role_reason": "This condition connects Preserving the original cut-off, correction and deliberation histories, and original URL with populations, comparators, measurement sites, ROIs, overall and subgroup findings, denominators, timing, prespecification, precision, reports, errata and harms for the selected overall-hip-BMD question.",
      "application_exception": "Retain original subclaim D and absent score, status and axes without inheriting parent C50 or axes. Null overall findings do not establish a precise absence of effect, equivalence or null findings at every site, and a small age subgroup is not extended into an overall effect. Falls, fractures and BMD, and female fallers versus BMD age subgroups, are distinguished. No erratum details, effects, CIs, P values, denominators, unique counts, independence or safety certification, or new exercise, prevention or treatment methods are created.",
      "criterion": "Original material and analysis scope for Preserving the original cut-off, correction and deliberation histories, and original URL must be linked to populations, comparators, measurement sites, denominators, overall and subgroup findings and timing for the selected BMD question, distinguishing stored summaries, unverified details and other outcomes.",
      "basis": "Preserved application conditions concerning questions, comparisons, reports versus trials, outcomes, denominators, errata and harms were referenced.",
      "condition_origin": "These are in-house application conditions preserved for the existing subclaim. They do not establish clinical preregistration, official-tool certification or completed content review.",
      "proposed_research": "Material needed: Material additions, condition revisions, applied observations and verdict changes must be linked as separate events and versions after preserving complete originals. This records needed materials; no new research was executed."
    },
    {
      "item_id": "N26",
      "question_type": "Evidence condition",
      "question": "Are material-slot counts external acquisition or quality scores?",
      "needed": "Report links, local and external slots and unique clinical units",
      "role": "Required",
      "role_reason": "This condition connects Report links, local and external slots, and unique clinical units with populations, comparators, measurement sites, ROIs, overall and subgroup findings, denominators, timing, prespecification, precision, reports, errata and harms for the selected overall-hip-BMD question.",
      "application_exception": "Retain original subclaim D and absent score, status and axes without inheriting parent C50 or axes. Null overall findings do not establish a precise absence of effect, equivalence or null findings at every site, and a small age subgroup is not extended into an overall effect. Falls, fractures and BMD, and female fallers versus BMD age subgroups, are distinguished. No erratum details, effects, CIs, P values, denominators, unique counts, independence or safety certification, or new exercise, prevention or treatment methods are created.",
      "criterion": "Original material and analysis scope for Report links, local and external slots, and unique clinical units must be linked to populations, comparators, measurement sites, denominators, overall and subgroup findings and timing for the selected BMD question, distinguishing stored summaries, unverified details and other outcomes.",
      "basis": "Preserved application conditions concerning questions, comparisons, reports versus trials, outcomes, denominators, errata and harms were referenced.",
      "condition_origin": "These are in-house application conditions preserved for the existing subclaim. They do not establish clinical preregistration, official-tool certification or completed content review.",
      "proposed_research": "Material needed: Actual acquisition and reading of originals, and trial, report and cohort relationships, are needed. Existing content review remains incomplete, external materials unread and unique counts unverified. This records needed materials; no new research was executed."
    },
    {
      "item_id": "N27",
      "question_type": "Evidence condition",
      "question": "How are new materials or changes to the question updated?",
      "needed": "Distinguishing evidence updates, condition revisions and original-verdict changes",
      "role": "Required",
      "role_reason": "This condition connects Distinguishing evidence updates, condition revisions and original-verdict changes with populations, comparators, measurement sites, ROIs, overall and subgroup findings, denominators, timing, prespecification, precision, reports, errata and harms for the selected overall-hip-BMD question.",
      "application_exception": "Retain original subclaim D and absent score, status and axes without inheriting parent C50 or axes. Null overall findings do not establish a precise absence of effect, equivalence or null findings at every site, and a small age subgroup is not extended into an overall effect. Falls, fractures and BMD, and female fallers versus BMD age subgroups, are distinguished. No erratum details, effects, CIs, P values, denominators, unique counts, independence or safety certification, or new exercise, prevention or treatment methods are created.",
      "criterion": "Original material and analysis scope for Distinguishing evidence updates, condition revisions and original-verdict changes must be linked to populations, comparators, measurement sites, denominators, overall and subgroup findings and timing for the selected BMD question, distinguishing stored summaries, unverified details and other outcomes.",
      "basis": "Preserved application conditions concerning questions, comparisons, reports versus trials, outcomes, denominators, errata and harms were referenced.",
      "condition_origin": "These are in-house application conditions preserved for the existing subclaim. They do not establish clinical preregistration, official-tool certification or completed content review.",
      "proposed_research": "Material needed: Complete originals, events, versions and change reasons must be retained and content reviewed. No new clinical calculations, effects, CIs, independence certification or exercise, prevention or treatment instructions are created. This records needed materials; no new research was executed."
    }
  ]
}