{ "schema_version": "chamgap-public-evidence-check-1.0", "public_id": "v3005-s0", "verdict_number": "3005", "title": "Laughter Yoga for Perceived Stress—Improvement Signal With Unclear Prespecification and Controls", "view_version": "1.0", "view_created_date": "2026-10-19", "criteria_version": "1.0", "criteria_date": "2026-10-06", "review_date": null, "legacy_evidence_date": "2026-09-07", "review_scope": { "materials_read": "Existing review summaries and stored records of methodological application", "clinical_papers_directly_read": false, "new_clinical_search": false, "limitation": "Existing stored summary and preserved methodology application records. External papers, abstracts, registration, protocols, SAPs, original result tables and support disclosures are unread, and review of existing content remains incomplete.", "date_meaning": "This is the date the stored materials were checked, not the date of a new search of the clinical literature." }, "claim_context": { "population": "The original populations are nonclinical students and nurses. Nurses working in psychiatric settings are not psychiatric patients. Report-specific diagnoses, selection, baseline stress, occupational distributions and applicability to other adults are unverified. Do not extend occupational samples to diagnosed patients or all adults.", "intervention": "The program combines laughter, clapping, breathing, playful movement and group interaction. Humorous video is a separate intervention. Report-specific components, instructors, contact, expectations, adherence and laughter-only contributions are unverified. Create no new yoga, breathing or treatment instructions.", "dose": "The key program used 8 sessions of 30 minutes as an original observation condition. Actual schedules, exposure, attendance, discontinuation and adherence in other reports are unverified. Do not turn recorded exposure into a recommended frequency or new practice method.", "comparator": "Distinguish no intervention in the key 70-person trial from laughter yoga, video and reading in the acute 120-person trial. Arm-specific attention, contact, expectations, social participation, breathing and direct perceived-stress comparisons with active social controls are unverified. Do not attribute video-related changes to laughter yoga.", "endpoint": "The selection is reduced perceived stress in nonclinical adults; preserve original subclaim C and concerns about no-intervention controls, prespecification and blinding. PSS, GHQ, burnout, well-being, self-efficacy, mental symptoms and cortisol/DHEA are distinct outcomes. Direct score differences, CIs and clinical-importance thresholds are unverified.", "duration": "Distinguish the original single-session, 5-week or 8-session contexts. Exact visits, measurement windows, persistence after completion and long-term observation for each report are unverified. Do not assign a general duration as identical follow-up for every report/measure or extend acute findings to long-term effects.", "excluded_extensions": [ "Back-calculating new score differences, CIs, standardized effects or clinical importance from F, P or partial-effect statistics", "Combining PSS, GHQ, burnout, well-being, self-efficacy, mental symptoms or cortisol/DHEA as one effect", "Selecting only favorable abstract/multivariate/session-level wording or newly resolving the recorded conflict", "Treating no intervention, active social controls, video and reading as the same control, or attributing video effects to laughter yoga", "Using all completed/analyzed or total samples as valid denominators for every measure, time or harm", "Counting shared reports, registration identifiers or repeated samples/arms/sessions as new independent-trial, participant or event totals", "Inheriting parent C with 50 points, Unknown safety or historical axes/verification as subclaim scores or new independence/safety certification", "Creating new yoga, breathing or medical practice instructions, cortisol-normalization or psychiatric-treatment recommendations" ] }, "requirements": [ { "item_id": "N01", "question_type": "Evidence condition", "question": "Which question is covered?", "needed": "The selected subclaim's population and outcome", "role": "Required", "role_reason": "This condition connects The selected subclaim's population and outcome with populations, programs, actual controls, measures, timing, denominators, models, prespecification, direct effects/CIs or harms for nonclinical perceived stress, distinguishing other mental-symptom measures, biomarkers and treatment claims.", "application_exception": "Preserve original subclaim C, positive signals and no-intervention/prespecification/blinding gaps. Distinguish absent subclaim score/status/axes from parent C with 50 points, Unknown safety and unrecorded precision. Do not convert large F/P or partial-effect statistics to direct score differences, CIs, importance thresholds or laughter-specific effects. Do not transfer other measures, cortisol, video, brief exposure or original samples to the same PSS effects/denominators. Create no new effects, CIs, totals, independence/safety certification or yoga/medical instructions.", "criterion": "Material for The selected subclaim's population and outcome must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.", "basis": "Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.", "condition_origin": "Internally applied conditions preserved for the existing subclaim. They do not establish preregistration, official-tool certification or completed content review.", "proposed_research": "Material needed: Individual content review and independent verification of the population and outcome boundaries remain incomplete. This records needed materials; no new research was executed.", "current_reports": [], "existence": "Display information in the original parent stored summary is preserved. Public availability, acquisition and actual reading of detailed external material are separately unverified.", "acquired_read": "Stored summary read; external abstracts, full texts, registration, protocols, SAPs and support disclosures unread", "observation": "The selection is reduced perceived stress in nonclinical adults. The existing subclaim is retained; no new claim is created.", "condition_status": "Partly verified", "status_reason": "The selected claim, parent material and reports are distinguished and transferred from the stored summary. Detailed original material is unverified and review of existing content remains incomplete. This does not establish completed clinical review or certification.", "missingness": "Individual content review and independent verification of the population and outcome boundaries remain incomplete.", "uncertainty": "External original material is unread and review of existing content remains incomplete. Original grades, scores, axes, historical verification and independence statements are not treated as new verdicts or certification.", "review_date": null, "reading_status": "Full text not read · Stored summary read", "additional_material": "Individual content review and independent verification of the population and outcome boundaries remain incomplete." }, { "item_id": "N02", "question_type": "Evidence condition", "question": "How does selected grade C differ from the parent verdict?", "needed": "The scope of the selected grade and overall verdict", "role": "Required", "role_reason": "This condition connects The scope of the selected grade and overall verdict with populations, programs, actual controls, measures, timing, denominators, models, prespecification, direct effects/CIs or harms for nonclinical perceived stress, distinguishing other mental-symptom measures, biomarkers and treatment claims.", "application_exception": "Preserve original subclaim C, positive signals and no-intervention/prespecification/blinding gaps. Distinguish absent subclaim score/status/axes from parent C with 50 points, Unknown safety and unrecorded precision. Do not convert large F/P or partial-effect statistics to direct score differences, CIs, importance thresholds or laughter-specific effects. Do not transfer other measures, cortisol, video, brief exposure or original samples to the same PSS effects/denominators. Create no new effects, CIs, totals, independence/safety certification or yoga/medical instructions.", "criterion": "Material for The scope of the selected grade and overall verdict must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.", "basis": "Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.", "condition_origin": "Internally applied conditions preserved for the existing subclaim. They do not establish preregistration, official-tool certification or completed content review.", "proposed_research": "Material needed: The selection has no separate score, status or assessment axes. No new grade or score is assigned. This records needed materials; no new research was executed.", "current_reports": [], "existence": "Display information in the original parent stored summary is preserved. Public availability, acquisition and actual reading of detailed external material are separately unverified.", "acquired_read": "Stored summary read; external abstracts, full texts, registration, protocols, SAPs and support disclosures unread", "observation": "Selected C includes positive trials alongside gaps in no-intervention controls, prespecification and blinding. Parent C50 and Unknown safety provide overall context, not a separate score or safety verdict for the selection.", "condition_status": "Partly verified", "status_reason": "The selected claim, parent material and reports are distinguished and transferred from the stored summary. Detailed original material is unverified and review of existing content remains incomplete. This does not establish completed clinical review or certification.", "missingness": "The selection has no separate score, status or assessment axes. No new grade or score is assigned.", "uncertainty": "External original material is unread and review of existing content remains incomplete. Original grades, scores, axes, historical verification and independence statements are not treated as new verdicts or certification.", "review_date": null, "reading_status": "Full text not read · Stored summary read", "additional_material": "The selection has no separate score, status or assessment axes. No new grade or score is assigned." }, { "item_id": "N03", "question_type": "Evidence condition", "question": "Are psychiatric nurses psychiatric patients?", "needed": "Report-specific populations, diagnoses and selection criteria", "role": "Required", "role_reason": "This condition connects Report-specific populations, diagnoses and selection criteria with populations, programs, actual controls, measures, timing, denominators, models, prespecification, direct effects/CIs or harms for nonclinical perceived stress, distinguishing other mental-symptom measures, biomarkers and treatment claims.", "application_exception": "Preserve original subclaim C, positive signals and no-intervention/prespecification/blinding gaps. Distinguish absent subclaim score/status/axes from parent C with 50 points, Unknown safety and unrecorded precision. Do not convert large F/P or partial-effect statistics to direct score differences, CIs, importance thresholds or laughter-specific effects. Do not transfer other measures, cortisol, video, brief exposure or original samples to the same PSS effects/denominators. Create no new effects, CIs, totals, independence/safety certification or yoga/medical instructions.", "criterion": "Material for Report-specific populations, diagnoses and selection criteria must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.", "basis": "Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.", "condition_origin": "Internally applied conditions preserved for the existing subclaim. They do not establish preregistration, official-tool certification or completed content review.", "proposed_research": "Material needed: Report-specific diagnoses, exclusions, baseline stress, age, occupational distributions and applicability to other adults are unverified. This records needed materials; no new research was executed.", "current_reports": [ "R01", "R02", "R03", "R04" ], "existence": "Display information in the original parent stored summary is preserved. Public availability, acquisition and actual reading of detailed external material are separately unverified.", "acquired_read": "Stored summary read; external abstracts, full texts, registration, protocols, SAPs and support disclosures unread", "observation": "The original populations are healthy students and nurses. Nurses working in psychiatric settings are not psychiatric patients.", "condition_status": "Partly verified", "status_reason": "The selected claim, parent material and reports are distinguished and transferred from the stored summary. Detailed original material is unverified and review of existing content remains incomplete. This does not establish completed clinical review or certification.", "missingness": "Report-specific diagnoses, exclusions, baseline stress, age, occupational distributions and applicability to other adults are unverified.", "uncertainty": "External original material is unread and review of existing content remains incomplete. Original grades, scores, axes, historical verification and independence statements are not treated as new verdicts or certification.", "review_date": null, "reading_status": "Full text not read · Stored summary read", "additional_material": "Report-specific diagnoses, exclusions, baseline stress, age, occupational distributions and applicability to other adults are unverified." }, { "item_id": "N04", "question_type": "Evidence condition", "question": "Is laughter itself the same as the group program?", "needed": "Program components and actual participation", "role": "Required", "role_reason": "This condition connects Program components and actual participation with populations, programs, actual controls, measures, timing, denominators, models, prespecification, direct effects/CIs or harms for nonclinical perceived stress, distinguishing other mental-symptom measures, biomarkers and treatment claims.", "application_exception": "Preserve original subclaim C, positive signals and no-intervention/prespecification/blinding gaps. Distinguish absent subclaim score/status/axes from parent C with 50 points, Unknown safety and unrecorded precision. Do not convert large F/P or partial-effect statistics to direct score differences, CIs, importance thresholds or laughter-specific effects. Do not transfer other measures, cortisol, video, brief exposure or original samples to the same PSS effects/denominators. Create no new effects, CIs, totals, independence/safety certification or yoga/medical instructions.", "criterion": "Material for Program components and actual participation must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.", "basis": "Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.", "condition_origin": "Internally applied conditions preserved for the existing subclaim. They do not establish preregistration, official-tool certification or completed content review.", "proposed_research": "Material needed: Report-specific components, instructors, contact, expectations, adherence and each component's contribution are unverified. This records needed materials; no new research was executed.", "current_reports": [ "R01", "R02", "R03", "R04" ], "existence": "Display information in the original parent stored summary is preserved. Public availability, acquisition and actual reading of detailed external material are separately unverified.", "acquired_read": "Stored summary read; external abstracts, full texts, registration, protocols, SAPs and support disclosures unread", "observation": "The program combines laughter, clapping, breathing, playful movements and group activity. It is not treated as a laughter-only effect.", "condition_status": "Partly verified", "status_reason": "The selected claim, parent material and reports are distinguished and transferred from the stored summary. Detailed original material is unverified and review of existing content remains incomplete. This does not establish completed clinical review or certification.", "missingness": "Report-specific components, instructors, contact, expectations, adherence and each component's contribution are unverified.", "uncertainty": "External original material is unread and review of existing content remains incomplete. Original grades, scores, axes, historical verification and independence statements are not treated as new verdicts or certification.", "review_date": null, "reading_status": "Full text not read · Stored summary read", "additional_material": "Report-specific components, instructors, contact, expectations, adherence and each component's contribution are unverified." }, { "item_id": "N05", "question_type": "Evidence condition", "question": "How do no intervention and active social controls differ?", "needed": "Arm-specific attention, contact, expectations and control content", "role": "Required", "role_reason": "This condition connects Arm-specific attention, contact, expectations and control content with populations, programs, actual controls, measures, timing, denominators, models, prespecification, direct effects/CIs or harms for nonclinical perceived stress, distinguishing other mental-symptom measures, biomarkers and treatment claims.", "application_exception": "Preserve original subclaim C, positive signals and no-intervention/prespecification/blinding gaps. Distinguish absent subclaim score/status/axes from parent C with 50 points, Unknown safety and unrecorded precision. Do not convert large F/P or partial-effect statistics to direct score differences, CIs, importance thresholds or laughter-specific effects. Do not transfer other measures, cortisol, video, brief exposure or original samples to the same PSS effects/denominators. Create no new effects, CIs, totals, independence/safety certification or yoga/medical instructions.", "criterion": "Material for Arm-specific attention, contact, expectations and control content must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.", "basis": "Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.", "condition_origin": "Internally applied conditions preserved for the existing subclaim. They do not establish preregistration, official-tool certification or completed content review.", "proposed_research": "Material needed: Arm-specific attention, contact and expectations, control specifications in other reports and direct comparisons of laughter-specific effects are unverified. This records needed materials; no new research was executed.", "current_reports": [ "R01", "R02", "R03" ], "existence": "Display information in the original parent stored summary is preserved. Public availability, acquisition and actual reading of detailed external material are separately unverified.", "acquired_read": "Stored summary read; external abstracts, full texts, registration, protocols, SAPs and support disclosures unread", "observation": "The key 70-person report compared a small-group program with no intervention. The original explanation identifies insufficient active social controls as a limitation.", "condition_status": "Partly verified", "status_reason": "The selected claim, parent material and reports are distinguished and transferred from the stored summary. Detailed original material is unverified and review of existing content remains incomplete. This does not establish completed clinical review or certification.", "missingness": "Arm-specific attention, contact and expectations, control specifications in other reports and direct comparisons of laughter-specific effects are unverified.", "uncertainty": "External original material is unread and review of existing content remains incomplete. Original grades, scores, axes, historical verification and independence statements are not treated as new verdicts or certification.", "review_date": null, "reading_status": "Full text not read · Stored summary read", "additional_material": "Arm-specific attention, contact and expectations, control specifications in other reports and direct comparisons of laughter-specific effects are unverified." }, { "item_id": "N06", "question_type": "Evidence condition", "question": "Do single and repeated programs show the same effect?", "needed": "Report-specific duration, frequency, exposure and follow-up", "role": "Required", "role_reason": "This condition connects Report-specific duration, frequency, exposure and follow-up with populations, programs, actual controls, measures, timing, denominators, models, prespecification, direct effects/CIs or harms for nonclinical perceived stress, distinguishing other mental-symptom measures, biomarkers and treatment claims.", "application_exception": "Preserve original subclaim C, positive signals and no-intervention/prespecification/blinding gaps. Distinguish absent subclaim score/status/axes from parent C with 50 points, Unknown safety and unrecorded precision. Do not convert large F/P or partial-effect statistics to direct score differences, CIs, importance thresholds or laughter-specific effects. Do not transfer other measures, cortisol, video, brief exposure or original samples to the same PSS effects/denominators. Create no new effects, CIs, totals, independence/safety certification or yoga/medical instructions.", "criterion": "Material for Report-specific duration, frequency, exposure and follow-up must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.", "basis": "Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.", "condition_origin": "Internally applied conditions preserved for the existing subclaim. They do not establish preregistration, official-tool certification or completed content review.", "proposed_research": "Material needed: Exact report-specific schedules, observation windows, actual exposure, adherence, valid denominators and persistence after completion are unverified. These are not practice recommendations. This records needed materials; no new research was executed.", "current_reports": [ "R01", "R02", "R03", "R04" ], "existence": "Display information in the original parent stored summary is preserved. Public availability, acquisition and actual reading of detailed external material are separately unverified.", "acquired_read": "Stored summary read; external abstracts, full texts, registration, protocols, SAPs and support disclosures unread", "observation": "The original summary distinguishes a single exposure in 120 participants from 5 weeks or 8 sessions in samples of 75/83/70. The key program's 8 sessions of 30 minutes are original observation conditions.", "condition_status": "Partly verified", "status_reason": "The selected claim, parent material and reports are distinguished and transferred from the stored summary. Detailed original material is unverified and review of existing content remains incomplete. This does not establish completed clinical review or certification.", "missingness": "Exact report-specific schedules, observation windows, actual exposure, adherence, valid denominators and persistence after completion are unverified. These are not practice recommendations.", "uncertainty": "External original material is unread and review of existing content remains incomplete. Original grades, scores, axes, historical verification and independence statements are not treated as new verdicts or certification.", "review_date": null, "reading_status": "Full text not read · Stored summary read", "additional_material": "Exact report-specific schedules, observation windows, actual exposure, adherence, valid denominators and persistence after completion are unverified. These are not practice recommendations." }, { "item_id": "N07", "question_type": "Evidence condition", "question": "What does the perceived-stress measure represent?", "needed": "Measure version, range, direction, timing and scores", "role": "Required", "role_reason": "This condition connects Measure version, range, direction, timing and scores with populations, programs, actual controls, measures, timing, denominators, models, prespecification, direct effects/CIs or harms for nonclinical perceived stress, distinguishing other mental-symptom measures, biomarkers and treatment claims.", "application_exception": "Preserve original subclaim C, positive signals and no-intervention/prespecification/blinding gaps. Distinguish absent subclaim score/status/axes from parent C with 50 points, Unknown safety and unrecorded precision. Do not convert large F/P or partial-effect statistics to direct score differences, CIs, importance thresholds or laughter-specific effects. Do not transfer other measures, cortisol, video, brief exposure or original samples to the same PSS effects/denominators. Create no new effects, CIs, totals, independence/safety certification or yoga/medical instructions.", "criterion": "Material for Measure version, range, direction, timing and scores must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.", "basis": "Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.", "condition_origin": "Internally applied conditions preserved for the existing subclaim. They do not establish preregistration, official-tool certification or completed content review.", "proposed_research": "Material needed: PSS version, range, direction, units, baseline and final scores, changes, aggregation, denominators and intervals are unverified. This records needed materials; no new research was executed.", "current_reports": [ "R01", "R02" ], "existence": "Display information in the original parent stored summary is preserved. Public availability, acquisition and actual reading of detailed external material are separately unverified.", "acquired_read": "Stored summary read; external abstracts, full texts, registration, protocols, SAPs and support disclosures unread", "observation": "The key report covers PSS/GHQ/burnout after 8 sessions. The selected outcome is perceived stress; PSS statistics are kept separate from other measures.", "condition_status": "Partly verified", "status_reason": "The selected claim, parent material and reports are distinguished and transferred from the stored summary. Detailed original material is unverified and review of existing content remains incomplete. This does not establish completed clinical review or certification.", "missingness": "PSS version, range, direction, units, baseline and final scores, changes, aggregation, denominators and intervals are unverified.", "uncertainty": "External original material is unread and review of existing content remains incomplete. Original grades, scores, axes, historical verification and independence statements are not treated as new verdicts or certification.", "review_date": null, "reading_status": "Full text not read · Stored summary read", "additional_material": "PSS version, range, direction, units, baseline and final scores, changes, aggregation, denominators and intervals are unverified." }, { "item_id": "N08", "question_type": "Evidence condition", "question": "Are other psychological measures also perceived stress?", "needed": "Definitions and outcome hierarchy for each measure", "role": "Required", "role_reason": "This condition connects Definitions and outcome hierarchy for each measure with populations, programs, actual controls, measures, timing, denominators, models, prespecification, direct effects/CIs or harms for nonclinical perceived stress, distinguishing other mental-symptom measures, biomarkers and treatment claims.", "application_exception": "Preserve original subclaim C, positive signals and no-intervention/prespecification/blinding gaps. Distinguish absent subclaim score/status/axes from parent C with 50 points, Unknown safety and unrecorded precision. Do not convert large F/P or partial-effect statistics to direct score differences, CIs, importance thresholds or laughter-specific effects. Do not transfer other measures, cortisol, video, brief exposure or original samples to the same PSS effects/denominators. Create no new effects, CIs, totals, independence/safety certification or yoga/medical instructions.", "criterion": "Material for Definitions and outcome hierarchy for each measure must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.", "basis": "Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.", "condition_origin": "Internally applied conditions preserved for the existing subclaim. They do not establish preregistration, official-tool certification or completed content review.", "proposed_research": "Material needed: Measure versions, primary/secondary hierarchy, direct effects, denominators, intervals and links to clinical diagnoses are unverified. This records needed materials; no new research was executed.", "current_reports": [ "R01", "R02", "R03" ], "existence": "Display information in the original parent stored summary is preserved. Public availability, acquisition and actual reading of detailed external material are separately unverified.", "acquired_read": "Stored summary read; external abstracts, full texts, registration, protocols, SAPs and support disclosures unread", "observation": "PSS, GHQ, burnout, well-being, self-efficacy and mental symptoms are separate outcomes. They are not combined into a single measure.", "condition_status": "Partly verified", "status_reason": "The selected claim, parent material and reports are distinguished and transferred from the stored summary. Detailed original material is unverified and review of existing content remains incomplete. This does not establish completed clinical review or certification.", "missingness": "Measure versions, primary/secondary hierarchy, direct effects, denominators, intervals and links to clinical diagnoses are unverified.", "uncertainty": "External original material is unread and review of existing content remains incomplete. Original grades, scores, axes, historical verification and independence statements are not treated as new verdicts or certification.", "review_date": null, "reading_status": "Full text not read · Stored summary read", "additional_material": "Measure versions, primary/secondary hierarchy, direct effects, denominators, intervals and links to clinical diagnoses are unverified." }, { "item_id": "N09", "question_type": "Evidence condition", "question": "What does the PSS group-by-time statistic show?", "needed": "The original statistic versus direct score differences", "role": "Required", "role_reason": "This condition connects The original statistic versus direct score differences with populations, programs, actual controls, measures, timing, denominators, models, prespecification, direct effects/CIs or harms for nonclinical perceived stress, distinguishing other mental-symptom measures, biomarkers and treatment claims.", "application_exception": "Preserve original subclaim C, positive signals and no-intervention/prespecification/blinding gaps. Distinguish absent subclaim score/status/axes from parent C with 50 points, Unknown safety and unrecorded precision. Do not convert large F/P or partial-effect statistics to direct score differences, CIs, importance thresholds or laughter-specific effects. Do not transfer other measures, cortisol, video, brief exposure or original samples to the same PSS effects/denominators. Create no new effects, CIs, totals, independence/safety certification or yoga/medical instructions.", "criterion": "Material for The original statistic versus direct score differences must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.", "basis": "Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.", "condition_origin": "Internally applied conditions preserved for the existing subclaim. They do not establish preregistration, official-tool certification or completed content review.", "proposed_research": "Material needed: Arm-specific scores and changes, adjusted between-arm differences and confidence intervals, models, variances, baseline and time windows are unverified. This records needed materials; no new research was executed.", "current_reports": [ "R01" ], "existence": "Display information in the original parent stored summary is preserved. Public availability, acquisition and actual reading of detailed external material are separately unverified.", "acquired_read": "Stored summary read; external abstracts, full texts, registration, protocols, SAPs and support disclosures unread", "observation": "The original result is PSS group-by-time F(1,68)=251.56, P<.001, partial eta-squared=.787. It is not converted into a direct score difference or a laughter-specific effect.", "condition_status": "Partly verified", "status_reason": "The selected claim, parent material and reports are distinguished and transferred from the stored summary. Detailed original material is unverified and review of existing content remains incomplete. This does not establish completed clinical review or certification.", "missingness": "Arm-specific scores and changes, adjusted between-arm differences and confidence intervals, models, variances, baseline and time windows are unverified.", "uncertainty": "External original material is unread and review of existing content remains incomplete. Original grades, scores, axes, historical verification and independence statements are not treated as new verdicts or certification.", "review_date": null, "reading_status": "Full text not read · Stored summary read", "additional_material": "Arm-specific scores and changes, adjusted between-arm differences and confidence intervals, models, variances, baseline and time windows are unverified." }, { "item_id": "N10", "question_type": "Evidence condition", "question": "Does complete participation establish every outcome denominator?", "needed": "Measure- and time-specific analysis samples and units", "role": "Required", "role_reason": "This condition connects Measure- and time-specific analysis samples and units with populations, programs, actual controls, measures, timing, denominators, models, prespecification, direct effects/CIs or harms for nonclinical perceived stress, distinguishing other mental-symptom measures, biomarkers and treatment claims.", "application_exception": "Preserve original subclaim C, positive signals and no-intervention/prespecification/blinding gaps. Distinguish absent subclaim score/status/axes from parent C with 50 points, Unknown safety and unrecorded precision. Do not convert large F/P or partial-effect statistics to direct score differences, CIs, importance thresholds or laughter-specific effects. Do not transfer other measures, cortisol, video, brief exposure or original samples to the same PSS effects/denominators. Create no new effects, CIs, totals, independence/safety certification or yoga/medical instructions.", "criterion": "Material for Measure- and time-specific analysis samples and units must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.", "basis": "Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.", "condition_origin": "Internally applied conditions preserved for the existing subclaim. They do not establish preregistration, official-tool certification or completed content review.", "proposed_research": "Material needed: Measure- and time-specific valid denominators, missingness, group/individual analysis units and correspondence with harms data are unverified. This records needed materials; no new research was executed.", "current_reports": [ "R01" ], "existence": "Display information in the original parent stored summary is preserved. Public availability, acquisition and actual reading of detailed external material are separately unverified.", "acquired_read": "Stored summary read; external abstracts, full texts, registration, protocols, SAPs and support disclosures unread", "observation": "The original statement is that all 70 psychiatric nurses, 35 versus 35, completed. Statistical degrees of freedom and small-group arrangements are not used to calculate new denominators.", "condition_status": "Partly verified", "status_reason": "The selected claim, parent material and reports are distinguished and transferred from the stored summary. Detailed original material is unverified and review of existing content remains incomplete. This does not establish completed clinical review or certification.", "missingness": "Measure- and time-specific valid denominators, missingness, group/individual analysis units and correspondence with harms data are unverified.", "uncertainty": "External original material is unread and review of existing content remains incomplete. Original grades, scores, axes, historical verification and independence statements are not treated as new verdicts or certification.", "review_date": null, "reading_status": "Full text not read · Stored summary read", "additional_material": "Measure- and time-specific valid denominators, missingness, group/individual analysis units and correspondence with harms data are unverified." }, { "item_id": "N11", "question_type": "Evidence condition", "question": "What limitation arises when the instructor is also the assessor?", "needed": "Role separation, blinding and data handling", "role": "Required", "role_reason": "This condition connects Role separation, blinding and data handling with populations, programs, actual controls, measures, timing, denominators, models, prespecification, direct effects/CIs or harms for nonclinical perceived stress, distinguishing other mental-symptom measures, biomarkers and treatment claims.", "application_exception": "Preserve original subclaim C, positive signals and no-intervention/prespecification/blinding gaps. Distinguish absent subclaim score/status/axes from parent C with 50 points, Unknown safety and unrecorded precision. Do not convert large F/P or partial-effect statistics to direct score differences, CIs, importance thresholds or laughter-specific effects. Do not transfer other measures, cortisol, video, brief exposure or original samples to the same PSS effects/denominators. Create no new effects, CIs, totals, independence/safety certification or yoga/medical instructions.", "criterion": "Material for Role separation, blinding and data handling must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.", "basis": "Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.", "condition_origin": "Internally applied conditions preserved for the existing subclaim. They do not establish preregistration, official-tool certification or completed content review.", "proposed_research": "Material needed: Assessment and recording blinding, role separation, expectation and attention controls, and data-handling procedures are unverified. This records needed materials; no new research was executed.", "current_reports": [ "R01" ], "existence": "Display information in the original parent stored summary is preserved. Public availability, acquisition and actual reading of detailed external material are separately unverified.", "acquired_read": "Stored summary read; external abstracts, full texts, registration, protocols, SAPs and support disclosures unread", "observation": "The original record states that the researcher also served as laughter-yoga instructor and assessor. This is separate from declarations of no external funding or conflicts.", "condition_status": "Partly verified", "status_reason": "The selected claim, parent material and reports are distinguished and transferred from the stored summary. Detailed original material is unverified and review of existing content remains incomplete. This does not establish completed clinical review or certification.", "missingness": "Assessment and recording blinding, role separation, expectation and attention controls, and data-handling procedures are unverified.", "uncertainty": "External original material is unread and review of existing content remains incomplete. Original grades, scores, axes, historical verification and independence statements are not treated as new verdicts or certification.", "review_date": null, "reading_status": "Full text not read · Stored summary read", "additional_material": "Assessment and recording blinding, role separation, expectation and attention controls, and data-handling procedures are unverified." }, { "item_id": "N12", "question_type": "Evidence condition", "question": "Were concerns about conduct and registration dates verified?", "needed": "Original schedules, registration, plans and amendments", "role": "Required", "role_reason": "This condition connects Original schedules, registration, plans and amendments with populations, programs, actual controls, measures, timing, denominators, models, prespecification, direct effects/CIs or harms for nonclinical perceived stress, distinguishing other mental-symptom measures, biomarkers and treatment claims.", "application_exception": "Preserve original subclaim C, positive signals and no-intervention/prespecification/blinding gaps. Distinguish absent subclaim score/status/axes from parent C with 50 points, Unknown safety and unrecorded precision. Do not convert large F/P or partial-effect statistics to direct score differences, CIs, importance thresholds or laughter-specific effects. Do not transfer other measures, cortisol, video, brief exposure or original samples to the same PSS effects/denominators. Create no new effects, CIs, totals, independence/safety certification or yoga/medical instructions.", "criterion": "Material for Original schedules, registration, plans and amendments must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.", "basis": "Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.", "condition_origin": "Internally applied conditions preserved for the existing subclaim. They do not establish preregistration, official-tool certification or completed content review.", "proposed_research": "Material needed: Exact conduct, registration and planning times, amendments, PSS hierarchy and consistency with original documents are unverified. This records needed materials; no new research was executed.", "current_reports": [ "R01" ], "existence": "Display information in the original parent stored summary is preserved. Public availability, acquisition and actual reading of detailed external material are separately unverified.", "acquired_read": "Stored summary read; external abstracts, full texts, registration, protocols, SAPs and support disclosures unread", "observation": "The original record retains concerns about consistency between conduct and registration schedules and about prespecification. This is not a new external registration check.", "condition_status": "Partly verified", "status_reason": "The selected claim, parent material and reports are distinguished and transferred from the stored summary. Detailed original material is unverified and review of existing content remains incomplete. This does not establish completed clinical review or certification.", "missingness": "Exact conduct, registration and planning times, amendments, PSS hierarchy and consistency with original documents are unverified.", "uncertainty": "External original material is unread and review of existing content remains incomplete. Original grades, scores, axes, historical verification and independence statements are not treated as new verdicts or certification.", "review_date": null, "reading_status": "Full text not read · Stored summary read", "additional_material": "Exact conduct, registration and planning times, amendments, PSS hierarchy and consistency with original documents are unverified." }, { "item_id": "N13", "question_type": "Evidence condition", "question": "Are the abstract's null statement and multivariate statistic the same test?", "needed": "Measures, contrasts, models and original results for each statement", "role": "Required", "role_reason": "This condition connects Measures, contrasts, models and original results for each statement with populations, programs, actual controls, measures, timing, denominators, models, prespecification, direct effects/CIs or harms for nonclinical perceived stress, distinguishing other mental-symptom measures, biomarkers and treatment claims.", "application_exception": "Preserve original subclaim C, positive signals and no-intervention/prespecification/blinding gaps. Distinguish absent subclaim score/status/axes from parent C with 50 points, Unknown safety and unrecorded precision. Do not convert large F/P or partial-effect statistics to direct score differences, CIs, importance thresholds or laughter-specific effects. Do not transfer other measures, cortisol, video, brief exposure or original samples to the same PSS effects/denominators. Create no new effects, CIs, totals, independence/safety certification or yoga/medical instructions.", "criterion": "Material for Measures, contrasts, models and original results for each statement must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.", "basis": "Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.", "condition_origin": "Internally applied conditions preserved for the existing subclaim. They do not establish preregistration, official-tool certification or completed content review.", "proposed_research": "Material needed: The outcome, contrast and hierarchy of each test, individual PSS effects and confidence intervals, and multivariate models and denominators are unverified. This records needed materials; no new research was executed.", "current_reports": [ "R02" ], "existence": "Display information in the original parent stored summary is preserved. Public availability, acquisition and actual reading of detailed external material are separately unverified.", "acquired_read": "Stored summary read; external abstracts, full texts, registration, protocols, SAPs and support disclosures unread", "observation": "The original record retains both an abstract between-arm null statement and a main-text multivariate interaction F=10.69, P<.001. No new full-text comparison resolved the conflict.", "condition_status": "Partly verified", "status_reason": "The selected claim, parent material and reports are distinguished and transferred from the stored summary. Detailed original material is unverified and review of existing content remains incomplete. This does not establish completed clinical review or certification.", "missingness": "The outcome, contrast and hierarchy of each test, individual PSS effects and confidence intervals, and multivariate models and denominators are unverified.", "uncertainty": "External original material is unread and review of existing content remains incomplete. Original grades, scores, axes, historical verification and independence statements are not treated as new verdicts or certification.", "review_date": null, "reading_status": "Full text not read · Stored summary read", "additional_material": "The outcome, contrast and hierarchy of each test, individual PSS effects and confidence intervals, and multivariate models and denominators are unverified." }, { "item_id": "N14", "question_type": "Evidence condition", "question": "What do the analyzed sample and retrospective registration establish?", "needed": "Total allocation, exclusions, completion and registration timing", "role": "Required", "role_reason": "This condition connects Total allocation, exclusions, completion and registration timing with populations, programs, actual controls, measures, timing, denominators, models, prespecification, direct effects/CIs or harms for nonclinical perceived stress, distinguishing other mental-symptom measures, biomarkers and treatment claims.", "application_exception": "Preserve original subclaim C, positive signals and no-intervention/prespecification/blinding gaps. Distinguish absent subclaim score/status/axes from parent C with 50 points, Unknown safety and unrecorded precision. Do not convert large F/P or partial-effect statistics to direct score differences, CIs, importance thresholds or laughter-specific effects. Do not transfer other measures, cortisol, video, brief exposure or original samples to the same PSS effects/denominators. Create no new effects, CIs, totals, independence/safety certification or yoga/medical instructions.", "criterion": "Material for Total allocation, exclusions, completion and registration timing must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.", "basis": "Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.", "condition_origin": "Internally applied conditions preserved for the existing subclaim. They do not establish preregistration, official-tool certification or completed content review.", "proposed_research": "Material needed: Total allocation and exclusions, arm- and measure-specific valid denominators, registration and planning times and amendments are unverified. This records needed materials; no new research was executed.", "current_reports": [ "R02" ], "existence": "Display information in the original parent stored summary is preserved. Public availability, acquisition and actual reading of detailed external material are separately unverified.", "acquired_read": "Stored summary read; external abstracts, full texts, registration, protocols, SAPs and support disclosures unread", "observation": "The original notation is 83 nursing students analyzed, 41 versus 42, alongside retrospective-registration concerns. This is distinguished from allocated, completed and measure-specific data.", "condition_status": "Partly verified", "status_reason": "The selected claim, parent material and reports are distinguished and transferred from the stored summary. Detailed original material is unverified and review of existing content remains incomplete. This does not establish completed clinical review or certification.", "missingness": "Total allocation and exclusions, arm- and measure-specific valid denominators, registration and planning times and amendments are unverified.", "uncertainty": "External original material is unread and review of existing content remains incomplete. Original grades, scores, axes, historical verification and independence statements are not treated as new verdicts or certification.", "review_date": null, "reading_status": "Full text not read · Stored summary read", "additional_material": "Total allocation and exclusions, arm- and measure-specific valid denominators, registration and planning times and amendments are unverified." }, { "item_id": "N15", "question_type": "Evidence condition", "question": "Are mental-symptom results direct PSS results?", "needed": "Existence of perceived-stress measurement and individual results", "role": "Required", "role_reason": "This condition connects Existence of perceived-stress measurement and individual results with populations, programs, actual controls, measures, timing, denominators, models, prespecification, direct effects/CIs or harms for nonclinical perceived stress, distinguishing other mental-symptom measures, biomarkers and treatment claims.", "application_exception": "Preserve original subclaim C, positive signals and no-intervention/prespecification/blinding gaps. Distinguish absent subclaim score/status/axes from parent C with 50 points, Unknown safety and unrecorded precision. Do not convert large F/P or partial-effect statistics to direct score differences, CIs, importance thresholds or laughter-specific effects. Do not transfer other measures, cortisol, video, brief exposure or original samples to the same PSS effects/denominators. Create no new effects, CIs, totals, independence/safety certification or yoga/medical instructions.", "criterion": "Material for Existence of perceived-stress measurement and individual results must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.", "basis": "Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.", "condition_origin": "Internally applied conditions preserved for the existing subclaim. They do not establish preregistration, official-tool certification or completed content review.", "proposed_research": "Material needed: The mental-symptom instrument, existence of PSS measurement and individual effects, arm-, time- and session-specific denominators and plans are unverified. This records needed materials; no new research was executed.", "current_reports": [ "R03" ], "existence": "Display information in the original parent stored summary is preserved. Public availability, acquisition and actual reading of detailed external material are separately unverified.", "acquired_read": "Stored summary read; external abstracts, full texts, registration, protocols, SAPs and support disclosures unread", "observation": "The Ozturk report describes positive mental-symptom results in 75 participants over 8 sessions and positive between-arm cortisol results in 3 of 8 sessions. These are not reassigned as direct selected perceived-stress values.", "condition_status": "Partly verified", "status_reason": "The selected claim, parent material and reports are distinguished and transferred from the stored summary. Detailed original material is unverified and review of existing content remains incomplete. This does not establish completed clinical review or certification.", "missingness": "The mental-symptom instrument, existence of PSS measurement and individual effects, arm-, time- and session-specific denominators and plans are unverified.", "uncertainty": "External original material is unread and review of existing content remains incomplete. Original grades, scores, axes, historical verification and independence statements are not treated as new verdicts or certification.", "review_date": null, "reading_status": "Full text not read · Stored summary read", "additional_material": "The mental-symptom instrument, existence of PSS measurement and individual effects, arm-, time- and session-specific denominators and plans are unverified." }, { "item_id": "N16", "question_type": "Evidence condition", "question": "Do acute biomarkers establish a perceived-stress effect?", "needed": "Direct perceived-stress outcomes versus biomarkers", "role": "Required", "role_reason": "This condition connects Direct perceived-stress outcomes versus biomarkers with populations, programs, actual controls, measures, timing, denominators, models, prespecification, direct effects/CIs or harms for nonclinical perceived stress, distinguishing other mental-symptom measures, biomarkers and treatment claims.", "application_exception": "Preserve original subclaim C, positive signals and no-intervention/prespecification/blinding gaps. Distinguish absent subclaim score/status/axes from parent C with 50 points, Unknown safety and unrecorded precision. Do not convert large F/P or partial-effect statistics to direct score differences, CIs, importance thresholds or laughter-specific effects. Do not transfer other measures, cortisol, video, brief exposure or original samples to the same PSS effects/denominators. Create no new effects, CIs, totals, independence/safety certification or yoga/medical instructions.", "criterion": "Material for Direct perceived-stress outcomes versus biomarkers must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.", "basis": "Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.", "condition_origin": "Internally applied conditions preserved for the existing subclaim. They do not establish preregistration, official-tool certification or completed content review.", "proposed_research": "Material needed: Existence of perceived-stress measurement and results, arm-specific denominators, exact cortisol contrasts and confidence intervals, and single-exposure and time-of-day plans are unverified. This records needed materials; no new research was executed.", "current_reports": [ "R04" ], "existence": "Display information in the original parent stored summary is preserved. Public availability, acquisition and actual reading of detailed external material are separately unverified.", "acquired_read": "Stored summary read; external abstracts, full texts, registration, protocols, SAPs and support disclosures unread", "observation": "The Fujisawa report covers acute 3-arm cortisol/DHEA results in 120 healthy students. The original statements that video also changed and DHEA was null are retained.", "condition_status": "Partly verified", "status_reason": "The selected claim, parent material and reports are distinguished and transferred from the stored summary. Detailed original material is unverified and review of existing content remains incomplete. This does not establish completed clinical review or certification.", "missingness": "Existence of perceived-stress measurement and results, arm-specific denominators, exact cortisol contrasts and confidence intervals, and single-exposure and time-of-day plans are unverified.", "uncertainty": "External original material is unread and review of existing content remains incomplete. Original grades, scores, axes, historical verification and independence statements are not treated as new verdicts or certification.", "review_date": null, "reading_status": "Full text not read · Stored summary read", "additional_material": "Existence of perceived-stress measurement and results, arm-specific denominators, exact cortisol contrasts and confidence intervals, and single-exposure and time-of-day plans are unverified." }, { "item_id": "N17", "question_type": "Evidence condition", "question": "Are changes with humorous video attributed to laughter yoga?", "needed": "Direct comparisons of different interventions", "role": "Required", "role_reason": "This condition connects Direct comparisons of different interventions with populations, programs, actual controls, measures, timing, denominators, models, prespecification, direct effects/CIs or harms for nonclinical perceived stress, distinguishing other mental-symptom measures, biomarkers and treatment claims.", "application_exception": "Preserve original subclaim C, positive signals and no-intervention/prespecification/blinding gaps. Distinguish absent subclaim score/status/axes from parent C with 50 points, Unknown safety and unrecorded precision. Do not convert large F/P or partial-effect statistics to direct score differences, CIs, importance thresholds or laughter-specific effects. Do not transfer other measures, cortisol, video, brief exposure or original samples to the same PSS effects/denominators. Create no new effects, CIs, totals, independence/safety certification or yoga/medical instructions.", "criterion": "Material for Direct comparisons of different interventions must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.", "basis": "Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.", "condition_origin": "Internally applied conditions preserved for the existing subclaim. They do not establish preregistration, official-tool certification or completed content review.", "proposed_research": "Material needed: Contributions of laughter, video, breathing, attention and social participation, and direct PSS contrasts are unverified. This records needed materials; no new research was executed.", "current_reports": [ "R04" ], "existence": "Display information in the original parent stored summary is preserved. Public availability, acquisition and actual reading of detailed external material are separately unverified.", "acquired_read": "Stored summary read; external abstracts, full texts, registration, protocols, SAPs and support disclosures unread", "observation": "Humorous video is a separate intervention. Video-related changes are not converted into laughter-yoga-specific effects.", "condition_status": "Partly verified", "status_reason": "The selected claim, parent material and reports are distinguished and transferred from the stored summary. Detailed original material is unverified and review of existing content remains incomplete. This does not establish completed clinical review or certification.", "missingness": "Contributions of laughter, video, breathing, attention and social participation, and direct PSS contrasts are unverified.", "uncertainty": "External original material is unread and review of existing content remains incomplete. Original grades, scores, axes, historical verification and independence statements are not treated as new verdicts or certification.", "review_date": null, "reading_status": "Full text not read · Stored summary read", "additional_material": "Contributions of laughter, video, breathing, attention and social participation, and direct PSS contrasts are unverified." }, { "item_id": "N18", "question_type": "Evidence condition", "question": "Does cortisol substitute for perceived stress or treatment?", "needed": "Links between biomarkers, self-report and treatment of diagnosed conditions", "role": "Required", "role_reason": "This condition connects Links between biomarkers, self-report and treatment of diagnosed conditions with populations, programs, actual controls, measures, timing, denominators, models, prespecification, direct effects/CIs or harms for nonclinical perceived stress, distinguishing other mental-symptom measures, biomarkers and treatment claims.", "application_exception": "Preserve original subclaim C, positive signals and no-intervention/prespecification/blinding gaps. Distinguish absent subclaim score/status/axes from parent C with 50 points, Unknown safety and unrecorded precision. Do not convert large F/P or partial-effect statistics to direct score differences, CIs, importance thresholds or laughter-specific effects. Do not transfer other measures, cortisol, video, brief exposure or original samples to the same PSS effects/denominators. Create no new effects, CIs, totals, independence/safety certification or yoga/medical instructions.", "criterion": "Material for Links between biomarkers, self-report and treatment of diagnosed conditions must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.", "basis": "Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.", "condition_origin": "Internally applied conditions preserved for the existing subclaim. They do not establish preregistration, official-tool certification or completed content review.", "proposed_research": "Material needed: Links between biomarkers, self-report and treatment of diagnosed conditions, exact intervals and correspondence with the selected outcome are unverified. This records needed materials; no new research was executed.", "current_reports": [ "R01", "R02", "R03", "R04" ], "existence": "Display information in the original parent stored summary is preserved. Public availability, acquisition and actual reading of detailed external material are separately unverified.", "acquired_read": "Stored summary read; external abstracts, full texts, registration, protocols, SAPs and support disclosures unread", "observation": "The original explanation separates salivary cortisol from perceived stress and retains gaps in consistency across sessions and trials. Cortisol is a separate subclaim.", "condition_status": "Partly verified", "status_reason": "The selected claim, parent material and reports are distinguished and transferred from the stored summary. Detailed original material is unverified and review of existing content remains incomplete. This does not establish completed clinical review or certification.", "missingness": "Links between biomarkers, self-report and treatment of diagnosed conditions, exact intervals and correspondence with the selected outcome are unverified.", "uncertainty": "External original material is unread and review of existing content remains incomplete. Original grades, scores, axes, historical verification and independence statements are not treated as new verdicts or certification.", "review_date": null, "reading_status": "Full text not read · Stored summary read", "additional_material": "Links between biomarkers, self-report and treatment of diagnosed conditions, exact intervals and correspondence with the selected outcome are unverified." }, { "item_id": "N19", "question_type": "Evidence condition", "question": "Do nonclinical results establish treatment of depression or anxiety disorders?", "needed": "Direct evidence in diagnosed patients and treatment outcomes", "role": "Required", "role_reason": "This condition connects Direct evidence in diagnosed patients and treatment outcomes with populations, programs, actual controls, measures, timing, denominators, models, prespecification, direct effects/CIs or harms for nonclinical perceived stress, distinguishing other mental-symptom measures, biomarkers and treatment claims.", "application_exception": "Preserve original subclaim C, positive signals and no-intervention/prespecification/blinding gaps. Distinguish absent subclaim score/status/axes from parent C with 50 points, Unknown safety and unrecorded precision. Do not convert large F/P or partial-effect statistics to direct score differences, CIs, importance thresholds or laughter-specific effects. Do not transfer other measures, cortisol, video, brief exposure or original samples to the same PSS effects/denominators. Create no new effects, CIs, totals, independence/safety certification or yoga/medical instructions.", "criterion": "Material for Direct evidence in diagnosed patients and treatment outcomes must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.", "basis": "Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.", "condition_origin": "Internally applied conditions preserved for the existing subclaim. They do not establish preregistration, official-tool certification or completed content review.", "proposed_research": "Material needed: Treatment, recovery and clinical events in diagnosed patients and their effects and intervals are outside this scope and unverified. This records needed materials; no new research was executed.", "current_reports": [], "existence": "Display information in the original parent stored summary is preserved. Public availability, acquisition and actual reading of detailed external material are separately unverified.", "acquired_read": "Stored summary read; external abstracts, full texts, registration, protocols, SAPs and support disclosures unread", "observation": "The original studies are not treatment trials in psychiatric patients. Nonclinical stress results are distinguished from disorder-treatment claims.", "condition_status": "Partly verified", "status_reason": "The selected claim, parent material and reports are distinguished and transferred from the stored summary. Detailed original material is unverified and review of existing content remains incomplete. This does not establish completed clinical review or certification.", "missingness": "Treatment, recovery and clinical events in diagnosed patients and their effects and intervals are outside this scope and unverified.", "uncertainty": "External original material is unread and review of existing content remains incomplete. Original grades, scores, axes, historical verification and independence statements are not treated as new verdicts or certification.", "review_date": null, "reading_status": "Full text not read · Stored summary read", "additional_material": "Treatment, recovery and clinical events in diagnosed patients and their effects and intervals are outside this scope and unverified." }, { "item_id": "N20", "question_type": "Evidence condition", "question": "Does a randomized-design label verify the procedure?", "needed": "Sequence generation, concealment, allocation units and selection procedures", "role": "Required", "role_reason": "This condition connects Sequence generation, concealment, allocation units and selection procedures with populations, programs, actual controls, measures, timing, denominators, models, prespecification, direct effects/CIs or harms for nonclinical perceived stress, distinguishing other mental-symptom measures, biomarkers and treatment claims.", "application_exception": "Preserve original subclaim C, positive signals and no-intervention/prespecification/blinding gaps. Distinguish absent subclaim score/status/axes from parent C with 50 points, Unknown safety and unrecorded precision. Do not convert large F/P or partial-effect statistics to direct score differences, CIs, importance thresholds or laughter-specific effects. Do not transfer other measures, cortisol, video, brief exposure or original samples to the same PSS effects/denominators. Create no new effects, CIs, totals, independence/safety certification or yoga/medical instructions.", "criterion": "Material for Sequence generation, concealment, allocation units and selection procedures must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.", "basis": "Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.", "condition_origin": "Internally applied conditions preserved for the existing subclaim. They do not establish preregistration, official-tool certification or completed content review.", "proposed_research": "Material needed: Sequence generation, allocation concealment and units, group and individual baseline balance, and selection and exclusion procedures are unverified. This records needed materials; no new research was executed.", "current_reports": [ "R01", "R02", "R03", "R04" ], "existence": "Display information in the original parent stored summary is preserved. Public availability, acquisition and actual reading of detailed external material are separately unverified.", "acquired_read": "Stored summary read; external abstracts, full texts, registration, protocols, SAPs and support disclosures unread", "observation": "Original randomized-design labels are retained alongside no-intervention controls, lack of blinding and the small-group context.", "condition_status": "Partly verified", "status_reason": "The selected claim, parent material and reports are distinguished and transferred from the stored summary. Detailed original material is unverified and review of existing content remains incomplete. This does not establish completed clinical review or certification.", "missingness": "Sequence generation, allocation concealment and units, group and individual baseline balance, and selection and exclusion procedures are unverified.", "uncertainty": "External original material is unread and review of existing content remains incomplete. Original grades, scores, axes, historical verification and independence statements are not treated as new verdicts or certification.", "review_date": null, "reading_status": "Full text not read · Stored summary read", "additional_material": "Sequence generation, allocation concealment and units, group and individual baseline balance, and selection and exclusion procedures are unverified." }, { "item_id": "N21", "question_type": "Evidence condition", "question": "How were self-report and assessor blinding handled?", "needed": "Recording, aggregation, analysis and expectation controls", "role": "Required", "role_reason": "This condition connects Recording, aggregation, analysis and expectation controls with populations, programs, actual controls, measures, timing, denominators, models, prespecification, direct effects/CIs or harms for nonclinical perceived stress, distinguishing other mental-symptom measures, biomarkers and treatment claims.", "application_exception": "Preserve original subclaim C, positive signals and no-intervention/prespecification/blinding gaps. Distinguish absent subclaim score/status/axes from parent C with 50 points, Unknown safety and unrecorded precision. Do not convert large F/P or partial-effect statistics to direct score differences, CIs, importance thresholds or laughter-specific effects. Do not transfer other measures, cortisol, video, brief exposure or original samples to the same PSS effects/denominators. Create no new effects, CIs, totals, independence/safety certification or yoga/medical instructions.", "criterion": "Material for Recording, aggregation, analysis and expectation controls must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.", "basis": "Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.", "condition_origin": "Internally applied conditions preserved for the existing subclaim. They do not establish preregistration, official-tool certification or completed content review.", "proposed_research": "Material needed: Assessment, aggregation and analysis blinding, PSS recording instruction and missingness, expectation controls and consistent procedures are unverified. This records needed materials; no new research was executed.", "current_reports": [ "R01", "R02", "R03", "R04" ], "existence": "Display information in the original parent stored summary is preserved. Public availability, acquisition and actual reading of detailed external material are separately unverified.", "acquired_read": "Stored summary read; external abstracts, full texts, registration, protocols, SAPs and support disclosures unread", "observation": "Lack of blinding and combined instructor/assessor roles remain limitations when interpreting self-reported stress.", "condition_status": "Partly verified", "status_reason": "The selected claim, parent material and reports are distinguished and transferred from the stored summary. Detailed original material is unverified and review of existing content remains incomplete. This does not establish completed clinical review or certification.", "missingness": "Assessment, aggregation and analysis blinding, PSS recording instruction and missingness, expectation controls and consistent procedures are unverified.", "uncertainty": "External original material is unread and review of existing content remains incomplete. Original grades, scores, axes, historical verification and independence statements are not treated as new verdicts or certification.", "review_date": null, "reading_status": "Full text not read · Stored summary read", "additional_material": "Assessment, aggregation and analysis blinding, PSS recording instruction and missingness, expectation controls and consistent procedures are unverified." }, { "item_id": "N22", "question_type": "Evidence condition", "question": "Were primary outcomes and multiple-analysis plans verified?", "needed": "Prespecified measures, models, times and multiplicity", "role": "Required", "role_reason": "This condition connects Prespecified measures, models, times and multiplicity with populations, programs, actual controls, measures, timing, denominators, models, prespecification, direct effects/CIs or harms for nonclinical perceived stress, distinguishing other mental-symptom measures, biomarkers and treatment claims.", "application_exception": "Preserve original subclaim C, positive signals and no-intervention/prespecification/blinding gaps. Distinguish absent subclaim score/status/axes from parent C with 50 points, Unknown safety and unrecorded precision. Do not convert large F/P or partial-effect statistics to direct score differences, CIs, importance thresholds or laughter-specific effects. Do not transfer other measures, cortisol, video, brief exposure or original samples to the same PSS effects/denominators. Create no new effects, CIs, totals, independence/safety certification or yoga/medical instructions.", "criterion": "Material for Prespecified measures, models, times and multiplicity must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.", "basis": "Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.", "condition_origin": "Internally applied conditions preserved for the existing subclaim. They do not establish preregistration, official-tool certification or completed content review.", "proposed_research": "Material needed: Primary/secondary hierarchy for PSS, GHQ, burnout, well-being and biomarkers, models, timing, multiplicity and planning times are unverified. This records needed materials; no new research was executed.", "current_reports": [ "R01", "R02", "R03", "R04" ], "existence": "Display information in the original parent stored summary is preserved. Public availability, acquisition and actual reading of detailed external material are separately unverified.", "acquired_read": "Stored summary read; external abstracts, full texts, registration, protocols, SAPs and support disclosures unread", "observation": "Unclear prespecification and retrospective-registration concerns are retained. A summary's primary-outcome label alone does not verify prespecification.", "condition_status": "Partly verified", "status_reason": "The selected claim, parent material and reports are distinguished and transferred from the stored summary. Detailed original material is unverified and review of existing content remains incomplete. This does not establish completed clinical review or certification.", "missingness": "Primary/secondary hierarchy for PSS, GHQ, burnout, well-being and biomarkers, models, timing, multiplicity and planning times are unverified.", "uncertainty": "External original material is unread and review of existing content remains incomplete. Original grades, scores, axes, historical verification and independence statements are not treated as new verdicts or certification.", "review_date": null, "reading_status": "Full text not read · Stored summary read", "additional_material": "Primary/secondary hierarchy for PSS, GHQ, burnout, well-being and biomarkers, models, timing, multiplicity and planning times are unverified." }, { "item_id": "N23", "question_type": "Evidence condition", "question": "What were baseline stress and other activities?", "needed": "Arm-specific baseline status and concurrent activities or treatment", "role": "Required", "role_reason": "This condition connects Arm-specific baseline status and concurrent activities or treatment with populations, programs, actual controls, measures, timing, denominators, models, prespecification, direct effects/CIs or harms for nonclinical perceived stress, distinguishing other mental-symptom measures, biomarkers and treatment claims.", "application_exception": "Preserve original subclaim C, positive signals and no-intervention/prespecification/blinding gaps. Distinguish absent subclaim score/status/axes from parent C with 50 points, Unknown safety and unrecorded precision. Do not convert large F/P or partial-effect statistics to direct score differences, CIs, importance thresholds or laughter-specific effects. Do not transfer other measures, cortisol, video, brief exposure or original samples to the same PSS effects/denominators. Create no new effects, CIs, totals, independence/safety certification or yoga/medical instructions.", "criterion": "Material for Arm-specific baseline status and concurrent activities or treatment must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.", "basis": "Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.", "condition_origin": "Internally applied conditions preserved for the existing subclaim. They do not establish preregistration, official-tool certification or completed content review.", "proposed_research": "Material needed: Baseline measures and status, arm-specific counseling, activities and treatment, confounding, adjustment and exposure changes are unverified. This records needed materials; no new research was executed.", "current_reports": [ "R01", "R02", "R03", "R04" ], "existence": "Display information in the original parent stored summary is preserved. Public availability, acquisition and actual reading of detailed external material are separately unverified.", "acquired_read": "Stored summary read; external abstracts, full texts, registration, protocols, SAPs and support disclosures unread", "observation": "The studies used different student and nurse samples, and group and attention effects need separation.", "condition_status": "Unverified", "status_reason": "The selected claim, parent material and reports are distinguished and transferred from the stored summary. Detailed original material is unverified and review of existing content remains incomplete. This does not establish completed clinical review or certification.", "missingness": "Baseline measures and status, arm-specific counseling, activities and treatment, confounding, adjustment and exposure changes are unverified.", "uncertainty": "External original material is unread and review of existing content remains incomplete. Original grades, scores, axes, historical verification and independence statements are not treated as new verdicts or certification.", "review_date": null, "reading_status": "Full text not read · Stored summary read", "additional_material": "Baseline measures and status, arm-specific counseling, activities and treatment, confounding, adjustment and exposure changes are unverified." }, { "item_id": "N24", "question_type": "Evidence condition", "question": "Are group-by-time, between-arm and multivariate results the same estimate?", "needed": "Analysis populations, units, contrasts and models", "role": "Required", "role_reason": "This condition connects Analysis populations, units, contrasts and models with populations, programs, actual controls, measures, timing, denominators, models, prespecification, direct effects/CIs or harms for nonclinical perceived stress, distinguishing other mental-symptom measures, biomarkers and treatment claims.", "application_exception": "Preserve original subclaim C, positive signals and no-intervention/prespecification/blinding gaps. Distinguish absent subclaim score/status/axes from parent C with 50 points, Unknown safety and unrecorded precision. Do not convert large F/P or partial-effect statistics to direct score differences, CIs, importance thresholds or laughter-specific effects. Do not transfer other measures, cortisol, video, brief exposure or original samples to the same PSS effects/denominators. Create no new effects, CIs, totals, independence/safety certification or yoga/medical instructions.", "criterion": "Material for Analysis populations, units, contrasts and models must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.", "basis": "Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.", "condition_origin": "Internally applied conditions preserved for the existing subclaim. They do not establish preregistration, official-tool certification or completed content review.", "proposed_research": "Material needed: Analysis populations and units, covariates, measures and contrasts, baseline adjustment, arm-specific tables and intervals are unverified. This records needed materials; no new research was executed.", "current_reports": [ "R01", "R02", "R03", "R04" ], "existence": "Display information in the original parent stored summary is preserved. Public availability, acquisition and actual reading of detailed external material are separately unverified.", "acquired_read": "Stored summary read; external abstracts, full texts, registration, protocols, SAPs and support disclosures unread", "observation": "PSS group-by-time, multivariate interactions and abstract between-arm statements are different analysis levels. No new direct effect is estimated.", "condition_status": "Partly verified", "status_reason": "The selected claim, parent material and reports are distinguished and transferred from the stored summary. Detailed original material is unverified and review of existing content remains incomplete. This does not establish completed clinical review or certification.", "missingness": "Analysis populations and units, covariates, measures and contrasts, baseline adjustment, arm-specific tables and intervals are unverified.", "uncertainty": "External original material is unread and review of existing content remains incomplete. Original grades, scores, axes, historical verification and independence statements are not treated as new verdicts or certification.", "review_date": null, "reading_status": "Full text not read · Stored summary read", "additional_material": "Analysis populations and units, covariates, measures and contrasts, baseline adjustment, arm-specific tables and intervals are unverified." }, { "item_id": "N25", "question_type": "Evidence condition", "question": "Do completion and analysis counts establish valid data for every measure?", "needed": "Arm-, measure-, visit- and session-specific missingness and exclusions", "role": "Required", "role_reason": "This condition connects Arm-, measure-, visit- and session-specific missingness and exclusions with populations, programs, actual controls, measures, timing, denominators, models, prespecification, direct effects/CIs or harms for nonclinical perceived stress, distinguishing other mental-symptom measures, biomarkers and treatment claims.", "application_exception": "Preserve original subclaim C, positive signals and no-intervention/prespecification/blinding gaps. Distinguish absent subclaim score/status/axes from parent C with 50 points, Unknown safety and unrecorded precision. Do not convert large F/P or partial-effect statistics to direct score differences, CIs, importance thresholds or laughter-specific effects. Do not transfer other measures, cortisol, video, brief exposure or original samples to the same PSS effects/denominators. Create no new effects, CIs, totals, independence/safety certification or yoga/medical instructions.", "criterion": "Material for Arm-, measure-, visit- and session-specific missingness and exclusions must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.", "basis": "Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.", "condition_origin": "Internally applied conditions preserved for the existing subclaim. They do not establish preregistration, official-tool certification or completed content review.", "proposed_research": "Material needed: Arm-, measure-, visit- and session-specific missingness, follow-up loss, exclusions, imputation and sensitivity analyses are unverified. This records needed materials; no new research was executed.", "current_reports": [ "R01", "R02", "R03", "R04" ], "existence": "Display information in the original parent stored summary is preserved. Public availability, acquisition and actual reading of detailed external material are separately unverified.", "acquired_read": "Stored summary read; external abstracts, full texts, registration, protocols, SAPs and support disclosures unread", "observation": "All 70 completing and 83 analyzed are the respective original report labels. Total samples of 75 and 120 are not used as arm- or endpoint-specific valid denominators.", "condition_status": "Unverified", "status_reason": "The selected claim, parent material and reports are distinguished and transferred from the stored summary. Detailed original material is unverified and review of existing content remains incomplete. This does not establish completed clinical review or certification.", "missingness": "Arm-, measure-, visit- and session-specific missingness, follow-up loss, exclusions, imputation and sensitivity analyses are unverified.", "uncertainty": "External original material is unread and review of existing content remains incomplete. Original grades, scores, axes, historical verification and independence statements are not treated as new verdicts or certification.", "review_date": null, "reading_status": "Full text not read · Stored summary read", "additional_material": "Arm-, measure-, visit- and session-specific missingness, follow-up loss, exclusions, imputation and sensitivity analyses are unverified." }, { "item_id": "N26", "question_type": "Evidence condition", "question": "Does a large statistic establish exact effects and clinical importance?", "needed": "Direct score differences, intervals and importance thresholds", "role": "Required", "role_reason": "This condition connects Direct score differences, intervals and importance thresholds with populations, programs, actual controls, measures, timing, denominators, models, prespecification, direct effects/CIs or harms for nonclinical perceived stress, distinguishing other mental-symptom measures, biomarkers and treatment claims.", "application_exception": "Preserve original subclaim C, positive signals and no-intervention/prespecification/blinding gaps. Distinguish absent subclaim score/status/axes from parent C with 50 points, Unknown safety and unrecorded precision. Do not convert large F/P or partial-effect statistics to direct score differences, CIs, importance thresholds or laughter-specific effects. Do not transfer other measures, cortisol, video, brief exposure or original samples to the same PSS effects/denominators. Create no new effects, CIs, totals, independence/safety certification or yoga/medical instructions.", "criterion": "Material for Direct score differences, intervals and importance thresholds must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.", "basis": "Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.", "condition_origin": "Internally applied conditions preserved for the existing subclaim. They do not establish preregistration, official-tool certification or completed content review.", "proposed_research": "Material needed: Exact direct score differences, confidence intervals, importance thresholds, variances, denominators and individual applicability are unverified. This records needed materials; no new research was executed.", "current_reports": [ "R01", "R02" ], "existence": "Display information in the original parent stored summary is preserved. Public availability, acquisition and actual reading of detailed external material are separately unverified.", "acquired_read": "Stored summary read; external abstracts, full texts, registration, protocols, SAPs and support disclosures unread", "observation": "The original explanation retains large statistics alongside insufficient prespecified hierarchy and active social controls. The magnitude of a laughter-specific effect is not established.", "condition_status": "Unverified", "status_reason": "The selected claim, parent material and reports are distinguished and transferred from the stored summary. Detailed original material is unverified and review of existing content remains incomplete. This does not establish completed clinical review or certification.", "missingness": "Exact direct score differences, confidence intervals, importance thresholds, variances, denominators and individual applicability are unverified.", "uncertainty": "External original material is unread and review of existing content remains incomplete. Original grades, scores, axes, historical verification and independence statements are not treated as new verdicts or certification.", "review_date": null, "reading_status": "Full text not read · Stored summary read", "additional_material": "Exact direct score differences, confidence intervals, importance thresholds, variances, denominators and individual applicability are unverified." }, { "item_id": "N27", "question_type": "Evidence condition", "question": "Are null, conflicting and mixed results retained?", "needed": "Complete results and selective reporting", "role": "Required", "role_reason": "This condition connects Complete results and selective reporting with populations, programs, actual controls, measures, timing, denominators, models, prespecification, direct effects/CIs or harms for nonclinical perceived stress, distinguishing other mental-symptom measures, biomarkers and treatment claims.", "application_exception": "Preserve original subclaim C, positive signals and no-intervention/prespecification/blinding gaps. Distinguish absent subclaim score/status/axes from parent C with 50 points, Unknown safety and unrecorded precision. Do not convert large F/P or partial-effect statistics to direct score differences, CIs, importance thresholds or laughter-specific effects. Do not transfer other measures, cortisol, video, brief exposure or original samples to the same PSS effects/denominators. Create no new effects, CIs, totals, independence/safety certification or yoga/medical instructions.", "criterion": "Material for Complete results and selective reporting must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.", "basis": "Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.", "condition_origin": "Internally applied conditions preserved for the existing subclaim. They do not establish preregistration, official-tool certification or completed content review.", "proposed_research": "Material needed: Complete external texts, tests and models, selected outcomes and contrasts, and the extent of omissions and selective reporting are unverified. This records needed materials; no new research was executed.", "current_reports": [ "R02", "R03", "R04" ], "existence": "Display information in the original parent stored summary is preserved. Public availability, acquisition and actual reading of detailed external material are separately unverified.", "acquired_read": "Stored summary read; external abstracts, full texts, registration, protocols, SAPs and support disclosures unread", "observation": "The conflicting Yaş statements, mixed Ozturk session results and Fujisawa video changes and null DHEA result are retained and separated from selected PSS.", "condition_status": "Partly verified", "status_reason": "The selected claim, parent material and reports are distinguished and transferred from the stored summary. Detailed original material is unverified and review of existing content remains incomplete. This does not establish completed clinical review or certification.", "missingness": "Complete external texts, tests and models, selected outcomes and contrasts, and the extent of omissions and selective reporting are unverified.", "uncertainty": "External original material is unread and review of existing content remains incomplete. Original grades, scores, axes, historical verification and independence statements are not treated as new verdicts or certification.", "review_date": null, "reading_status": "Full text not read · Stored summary read", "additional_material": "Complete external texts, tests and models, selected outcomes and contrasts, and the extent of omissions and selective reporting are unverified." }, { "item_id": "N28", "question_type": "Evidence condition", "question": "Are different samples, durations and controls pooled?", "needed": "Condition-specific direct results and prespecified subgroups", "role": "Required", "role_reason": "This condition connects Condition-specific direct results and prespecified subgroups with populations, programs, actual controls, measures, timing, denominators, models, prespecification, direct effects/CIs or harms for nonclinical perceived stress, distinguishing other mental-symptom measures, biomarkers and treatment claims.", "application_exception": "Preserve original subclaim C, positive signals and no-intervention/prespecification/blinding gaps. Distinguish absent subclaim score/status/axes from parent C with 50 points, Unknown safety and unrecorded precision. Do not convert large F/P or partial-effect statistics to direct score differences, CIs, importance thresholds or laughter-specific effects. Do not transfer other measures, cortisol, video, brief exposure or original samples to the same PSS effects/denominators. Create no new effects, CIs, totals, independence/safety certification or yoga/medical instructions.", "criterion": "Material for Condition-specific direct results and prespecified subgroups must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.", "basis": "Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.", "condition_origin": "Internally applied conditions preserved for the existing subclaim. They do not establish preregistration, official-tool certification or completed content review.", "proposed_research": "Material needed: Prespecified subgroups for the selected measure, direct differences, condition-specific intervals and models and all included data are unverified. This records needed materials; no new research was executed.", "current_reports": [ "R01", "R02", "R03", "R04" ], "existence": "Display information in the original parent stored summary is preserved. Public availability, acquisition and actual reading of detailed external material are separately unverified.", "acquired_read": "Stored summary read; external abstracts, full texts, registration, protocols, SAPs and support disclosures unread", "observation": "Populations, training, contact, duration and endpoints differ. No common pooled effect is newly calculated.", "condition_status": "Partly verified", "status_reason": "The selected claim, parent material and reports are distinguished and transferred from the stored summary. Detailed original material is unverified and review of existing content remains incomplete. This does not establish completed clinical review or certification.", "missingness": "Prespecified subgroups for the selected measure, direct differences, condition-specific intervals and models and all included data are unverified.", "uncertainty": "External original material is unread and review of existing content remains incomplete. Original grades, scores, axes, historical verification and independence statements are not treated as new verdicts or certification.", "review_date": null, "reading_status": "Full text not read · Stored summary read", "additional_material": "Prespecified subgroups for the selected measure, direct differences, condition-specific intervals and models and all included data are unverified." }, { "item_id": "N29", "question_type": "Evidence condition", "question": "Do short programs answer long-term questions for all adults?", "needed": "Persistence after completion and direct population-specific data", "role": "Required", "role_reason": "This condition connects Persistence after completion and direct population-specific data with populations, programs, actual controls, measures, timing, denominators, models, prespecification, direct effects/CIs or harms for nonclinical perceived stress, distinguishing other mental-symptom measures, biomarkers and treatment claims.", "application_exception": "Preserve original subclaim C, positive signals and no-intervention/prespecification/blinding gaps. Distinguish absent subclaim score/status/axes from parent C with 50 points, Unknown safety and unrecorded precision. Do not convert large F/P or partial-effect statistics to direct score differences, CIs, importance thresholds or laughter-specific effects. Do not transfer other measures, cortisol, video, brief exposure or original samples to the same PSS effects/denominators. Create no new effects, CIs, totals, independence/safety certification or yoga/medical instructions.", "criterion": "Material for Persistence after completion and direct population-specific data must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.", "basis": "Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.", "condition_origin": "Internally applied conditions preserved for the existing subclaim. They do not establish preregistration, official-tool certification or completed content review.", "proposed_research": "Material needed: Persistence after completion, long-term and specific populations, prespecified program- and baseline-specific differences and direct intervals are unverified. This records needed materials; no new research was executed.", "current_reports": [ "R01", "R02", "R03", "R04" ], "existence": "Display information in the original parent stored summary is preserved. Public availability, acquisition and actual reading of detailed external material are separately unverified.", "acquired_read": "Stored summary read; external abstracts, full texts, registration, protocols, SAPs and support disclosures unread", "observation": "Single-exposure, several-week and 8-session evidence is not extended to all adults, long-term stress or disorder treatment.", "condition_status": "Partly verified", "status_reason": "The selected claim, parent material and reports are distinguished and transferred from the stored summary. Detailed original material is unverified and review of existing content remains incomplete. This does not establish completed clinical review or certification.", "missingness": "Persistence after completion, long-term and specific populations, prespecified program- and baseline-specific differences and direct intervals are unverified.", "uncertainty": "External original material is unread and review of existing content remains incomplete. Original grades, scores, axes, historical verification and independence statements are not treated as new verdicts or certification.", "review_date": null, "reading_status": "Full text not read · Stored summary read", "additional_material": "Persistence after completion, long-term and specific populations, prespecified program- and baseline-specific differences and direct intervals are unverified." }, { "item_id": "N30", "question_type": "Evidence condition", "question": "Is the report count a total of independent trials or participants?", "needed": "Related reports, registration, recruitment and overlap", "role": "Required", "role_reason": "This condition connects Related reports, registration, recruitment and overlap with populations, programs, actual controls, measures, timing, denominators, models, prespecification, direct effects/CIs or harms for nonclinical perceived stress, distinguishing other mental-symptom measures, biomarkers and treatment claims.", "application_exception": "Preserve original subclaim C, positive signals and no-intervention/prespecification/blinding gaps. Distinguish absent subclaim score/status/axes from parent C with 50 points, Unknown safety and unrecorded precision. Do not convert large F/P or partial-effect statistics to direct score differences, CIs, importance thresholds or laughter-specific effects. Do not transfer other measures, cortisol, video, brief exposure or original samples to the same PSS effects/denominators. Create no new effects, CIs, totals, independence/safety certification or yoga/medical instructions.", "criterion": "Material for Related reports, registration, recruitment and overlap must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.", "basis": "Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.", "condition_origin": "Internally applied conditions preserved for the existing subclaim. They do not establish preregistration, official-tool certification or completed content review.", "proposed_research": "Material needed: Correspondence between registration, recruitment, groups and related reports, and unique trial, participant and event counts are unverified. This records needed materials; no new research was executed.", "current_reports": [ "R01", "R02", "R03", "R04" ], "existence": "Display information in the original parent stored summary is preserved. Public availability, acquisition and actual reading of detailed external material are separately unverified.", "acquired_read": "Stored summary read; external abstracts, full texts, registration, protocols, SAPs and support disclosures unread", "observation": "The 4 preserved reports are linked; the selected question, parent and cortisol subclaim share them. Original labels such as R1/I2 are not treated as new independence certification.", "condition_status": "Partly verified", "status_reason": "The selected claim, parent material and reports are distinguished and transferred from the stored summary. Detailed original material is unverified and review of existing content remains incomplete. This does not establish completed clinical review or certification.", "missingness": "Correspondence between registration, recruitment, groups and related reports, and unique trial, participant and event counts are unverified.", "uncertainty": "External original material is unread and review of existing content remains incomplete. Original grades, scores, axes, historical verification and independence statements are not treated as new verdicts or certification.", "review_date": null, "reading_status": "Full text not read · Stored summary read", "additional_material": "Correspondence between registration, recruitment, groups and related reports, and unique trial, participant and event counts are unverified." }, { "item_id": "N31", "question_type": "Evidence condition", "question": "Does a registration identifier mean its content was checked now?", "needed": "Registration originals, amendments, plans and report correspondence", "role": "Required", "role_reason": "This condition connects Registration originals, amendments, plans and report correspondence with populations, programs, actual controls, measures, timing, denominators, models, prespecification, direct effects/CIs or harms for nonclinical perceived stress, distinguishing other mental-symptom measures, biomarkers and treatment claims.", "application_exception": "Preserve original subclaim C, positive signals and no-intervention/prespecification/blinding gaps. Distinguish absent subclaim score/status/axes from parent C with 50 points, Unknown safety and unrecorded precision. Do not convert large F/P or partial-effect statistics to direct score differences, CIs, importance thresholds or laughter-specific effects. Do not transfer other measures, cortisol, video, brief exposure or original samples to the same PSS effects/denominators. Create no new effects, CIs, totals, independence/safety certification or yoga/medical instructions.", "criterion": "Material for Registration originals, amendments, plans and report correspondence must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.", "basis": "Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.", "condition_origin": "Internally applied conditions preserved for the existing subclaim. They do not establish preregistration, official-tool certification or completed content review.", "proposed_research": "Material needed: Registration, amendment and planning times and correspondence with recruitment, endpoints and reports were not verified in this work. This records needed materials; no new research was executed.", "current_reports": [ "R01", "R02", "R03", "R04" ], "existence": "Display information in the original parent stored summary is preserved. Public availability, acquisition and actual reading of detailed external material are separately unverified.", "acquired_read": "Stored summary read; external abstracts, full texts, registration, protocols, SAPs and support disclosures unread", "observation": "Original records of NCT07015372, NCT06175936, unable to verify, and UMIN000019409 are retained. UMIN was not relabeled as NCT and external content was not newly queried.", "condition_status": "Partly verified", "status_reason": "The selected claim, parent material and reports are distinguished and transferred from the stored summary. Detailed original material is unverified and review of existing content remains incomplete. This does not establish completed clinical review or certification.", "missingness": "Registration, amendment and planning times and correspondence with recruitment, endpoints and reports were not verified in this work.", "uncertainty": "External original material is unread and review of existing content remains incomplete. Original grades, scores, axes, historical verification and independence statements are not treated as new verdicts or certification.", "review_date": null, "reading_status": "Full text not read · Stored summary read", "additional_material": "Registration, amendment and planning times and correspondence with recruitment, endpoints and reports were not verified in this work." }, { "item_id": "N32", "question_type": "Evidence condition", "question": "Are funding/conflict declarations the same as combined roles?", "needed": "Support, contracts, involvement and role separation", "role": "Required", "role_reason": "This condition connects Support, contracts, involvement and role separation with populations, programs, actual controls, measures, timing, denominators, models, prespecification, direct effects/CIs or harms for nonclinical perceived stress, distinguishing other mental-symptom measures, biomarkers and treatment claims.", "application_exception": "Preserve original subclaim C, positive signals and no-intervention/prespecification/blinding gaps. Distinguish absent subclaim score/status/axes from parent C with 50 points, Unknown safety and unrecorded precision. Do not convert large F/P or partial-effect statistics to direct score differences, CIs, importance thresholds or laughter-specific effects. Do not transfer other measures, cortisol, video, brief exposure or original samples to the same PSS effects/denominators. Create no new effects, CIs, totals, independence/safety certification or yoga/medical instructions.", "criterion": "Material for Support, contracts, involvement and role separation must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.", "basis": "Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.", "condition_origin": "Internally applied conditions preserved for the existing subclaim. They do not establish preregistration, official-tool certification or completed content review.", "proposed_research": "Material needed: Support, contracts, training, analysis and publication involvement, current conflict disclosures and independent confirmation are unverified. This records needed materials; no new research was executed.", "current_reports": [ "R01", "R02", "R03", "R04" ], "existence": "Display information in the original parent stored summary is preserved. Public availability, acquisition and actual reading of detailed external material are separately unverified.", "acquired_read": "Stored summary read; external abstracts, full texts, registration, protocols, SAPs and support disclosures unread", "observation": "Bilgihan's declaration of no external funding or conflicts is retained alongside combined instructor/assessor roles. Funding in the other 3 reports was unable to be verified.", "condition_status": "Partly verified", "status_reason": "The selected claim, parent material and reports are distinguished and transferred from the stored summary. Detailed original material is unverified and review of existing content remains incomplete. This does not establish completed clinical review or certification.", "missingness": "Support, contracts, training, analysis and publication involvement, current conflict disclosures and independent confirmation are unverified.", "uncertainty": "External original material is unread and review of existing content remains incomplete. Original grades, scores, axes, historical verification and independence statements are not treated as new verdicts or certification.", "review_date": null, "reading_status": "Full text not read · Stored summary read", "additional_material": "Support, contracts, training, analysis and publication involvement, current conflict disclosures and independent confirmation are unverified." }, { "item_id": "N33", "question_type": "Evidence condition", "question": "What material was actually read here?", "needed": "Stored summaries versus external originals", "role": "Required", "role_reason": "This condition connects Stored summaries versus external originals with populations, programs, actual controls, measures, timing, denominators, models, prespecification, direct effects/CIs or harms for nonclinical perceived stress, distinguishing other mental-symptom measures, biomarkers and treatment claims.", "application_exception": "Preserve original subclaim C, positive signals and no-intervention/prespecification/blinding gaps. Distinguish absent subclaim score/status/axes from parent C with 50 points, Unknown safety and unrecorded precision. Do not convert large F/P or partial-effect statistics to direct score differences, CIs, importance thresholds or laughter-specific effects. Do not transfer other measures, cortisol, video, brief exposure or original samples to the same PSS effects/denominators. Create no new effects, CIs, totals, independence/safety certification or yoga/medical instructions.", "criterion": "Material for Stored summaries versus external originals must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.", "basis": "Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.", "condition_origin": "Internally applied conditions preserved for the existing subclaim. They do not establish preregistration, official-tool certification or completed content review.", "proposed_research": "Material needed: External identity, content, availability and acquisition, measure-specific tables, models, plans and registration are unverified. This records needed materials; no new research was executed.", "current_reports": [ "R01", "R02", "R03", "R04" ], "existence": "Display information in the original parent stored summary is preserved. Public availability, acquisition and actual reading of detailed external material are separately unverified.", "acquired_read": "Stored summary read; external abstracts, full texts, registration, protocols, SAPs and support disclosures unread", "observation": "The complete stored parent summary and selected question were read for production. External abstracts, full texts and registration materials were unread and access was not attempted in this work.", "condition_status": "Partly verified", "status_reason": "The selected claim, parent material and reports are distinguished and transferred from the stored summary. Detailed original material is unverified and review of existing content remains incomplete. This does not establish completed clinical review or certification.", "missingness": "External identity, content, availability and acquisition, measure-specific tables, models, plans and registration are unverified.", "uncertainty": "External original material is unread and review of existing content remains incomplete. Original grades, scores, axes, historical verification and independence statements are not treated as new verdicts or certification.", "review_date": null, "reading_status": "Full text not read · Stored summary read", "additional_material": "External identity, content, availability and acquisition, measure-specific tables, models, plans and registration are unverified." }, { "item_id": "N34", "question_type": "Evidence condition", "question": "What do the evidence date and bibliographic years mean?", "needed": "The original evidence reference date and historical reading records", "role": "Required", "role_reason": "This condition connects The original evidence reference date and historical reading records with populations, programs, actual controls, measures, timing, denominators, models, prespecification, direct effects/CIs or harms for nonclinical perceived stress, distinguishing other mental-symptom measures, biomarkers and treatment claims.", "application_exception": "Preserve original subclaim C, positive signals and no-intervention/prespecification/blinding gaps. Distinguish absent subclaim score/status/axes from parent C with 50 points, Unknown safety and unrecorded precision. Do not convert large F/P or partial-effect statistics to direct score differences, CIs, importance thresholds or laughter-specific effects. Do not transfer other measures, cortisol, video, brief exposure or original samples to the same PSS effects/denominators. Create no new effects, CIs, totals, independence/safety certification or yoga/medical instructions.", "criterion": "Material for The original evidence reference date and historical reading records must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.", "basis": "Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.", "condition_origin": "Internally applied conditions preserved for the existing subclaim. They do not establish preregistration, official-tool certification or completed content review.", "proposed_research": "Material needed: The original search end date, historical access locations and times, and current external materials and correction details are unverified. The reference date is not a new external reading date. This records needed materials; no new research was executed.", "current_reports": [ "R01", "R02", "R03", "R04" ], "existence": "Display information in the original parent stored summary is preserved. Public availability, acquisition and actual reading of detailed external material are separately unverified.", "acquired_read": "Stored summary read; external abstracts, full texts, registration, protocols, SAPs and support disclosures unread", "observation": "The original evidence date is 2026-09-07 and the corrections list is empty. Bibliographies from 2026/2025/2021/2018 and registration concerns are retained as originally recorded.", "condition_status": "Partly verified", "status_reason": "The selected claim, parent material and reports are distinguished and transferred from the stored summary. Detailed original material is unverified and review of existing content remains incomplete. This does not establish completed clinical review or certification.", "missingness": "The original search end date, historical access locations and times, and current external materials and correction details are unverified. The reference date is not a new external reading date.", "uncertainty": "External original material is unread and review of existing content remains incomplete. Original grades, scores, axes, historical verification and independence statements are not treated as new verdicts or certification.", "review_date": null, "reading_status": "Full text not read · Stored summary read", "additional_material": "The original search end date, historical access locations and times, and current external materials and correction details are unverified. The reference date is not a new external reading date." }, { "item_id": "N35", "question_type": "Evidence condition", "question": "How are the selected question and parent explanation retained?", "needed": "Korean/English selected wording and outcome scope", "role": "Required", "role_reason": "This condition connects Korean/English selected wording and outcome scope with populations, programs, actual controls, measures, timing, denominators, models, prespecification, direct effects/CIs or harms for nonclinical perceived stress, distinguishing other mental-symptom measures, biomarkers and treatment claims.", "application_exception": "Preserve original subclaim C, positive signals and no-intervention/prespecification/blinding gaps. Distinguish absent subclaim score/status/axes from parent C with 50 points, Unknown safety and unrecorded precision. Do not convert large F/P or partial-effect statistics to direct score differences, CIs, importance thresholds or laughter-specific effects. Do not transfer other measures, cortisol, video, brief exposure or original samples to the same PSS effects/denominators. Create no new effects, CIs, totals, independence/safety certification or yoga/medical instructions.", "criterion": "Material for Korean/English selected wording and outcome scope must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.", "basis": "Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.", "condition_origin": "Internally applied conditions preserved for the existing subclaim. They do not establish preregistration, official-tool certification or completed content review.", "proposed_research": "Material needed: Detailed external translation and correction comparisons and individual content review remain incomplete. No new selected score or status is created. This records needed materials; no new research was executed.", "current_reports": [ "R01", "R02", "R03", "R04" ], "existence": "Display information in the original parent stored summary is preserved. Public availability, acquisition and actual reading of detailed external material are separately unverified.", "acquired_read": "Stored summary read; external abstracts, full texts, registration, protocols, SAPs and support disclosures unread", "observation": "The selected English wording is Reduced perceived stress in nonclinical adults. Positive signals and no-intervention, prespecification and blinding limitations are separated from parent cortisol and treatment explanations.", "condition_status": "Partly verified", "status_reason": "The selected claim, parent material and reports are distinguished and transferred from the stored summary. Detailed original material is unverified and review of existing content remains incomplete. This does not establish completed clinical review or certification.", "missingness": "Detailed external translation and correction comparisons and individual content review remain incomplete. No new selected score or status is created.", "uncertainty": "External original material is unread and review of existing content remains incomplete. Original grades, scores, axes, historical verification and independence statements are not treated as new verdicts or certification.", "review_date": null, "reading_status": "Full text not read · Stored summary read", "additional_material": "Detailed external translation and correction comparisons and individual content review remain incomplete. No new selected score or status is created." }, { "item_id": "N36", "question_type": "Evidence condition", "question": "Do parent assessment axes provide new certification for the selection?", "needed": "Parent records versus selected assessment", "role": "Required", "role_reason": "This condition connects Parent records versus selected assessment with populations, programs, actual controls, measures, timing, denominators, models, prespecification, direct effects/CIs or harms for nonclinical perceived stress, distinguishing other mental-symptom measures, biomarkers and treatment claims.", "application_exception": "Preserve original subclaim C, positive signals and no-intervention/prespecification/blinding gaps. Distinguish absent subclaim score/status/axes from parent C with 50 points, Unknown safety and unrecorded precision. Do not convert large F/P or partial-effect statistics to direct score differences, CIs, importance thresholds or laughter-specific effects. Do not transfer other measures, cortisol, video, brief exposure or original samples to the same PSS effects/denominators. Create no new effects, CIs, totals, independence/safety certification or yoga/medical instructions.", "criterion": "Material for Parent records versus selected assessment must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.", "basis": "Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.", "condition_origin": "Internally applied conditions preserved for the existing subclaim. They do not establish preregistration, official-tool certification or completed content review.", "proposed_research": "Material needed: No new formal selected assessment or precision, independence, prespecification or quality certification was performed. This records needed materials; no new research was executed.", "current_reports": [ "R01", "R02", "R03", "R04" ], "existence": "Display information in the original parent stored summary is preserved. Public availability, acquisition and actual reading of detailed external material are separately unverified.", "acquired_read": "Stored summary read; external abstracts, full texts, registration, protocols, SAPs and support disclosures unread", "observation": "The parent's unspecified precision, B/P/R1/I2/EX/B2, false flags, empty override and deliberation, and Korean/English originals are preserved internally. No new selected axes, score or status exist.", "condition_status": "Partly verified", "status_reason": "The selected claim, parent material and reports are distinguished and transferred from the stored summary. Detailed original material is unverified and review of existing content remains incomplete. This does not establish completed clinical review or certification.", "missingness": "No new formal selected assessment or precision, independence, prespecification or quality certification was performed.", "uncertainty": "External original material is unread and review of existing content remains incomplete. Original grades, scores, axes, historical verification and independence statements are not treated as new verdicts or certification.", "review_date": null, "reading_status": "Full text not read · Stored summary read", "additional_material": "No new formal selected assessment or precision, independence, prespecification or quality certification was performed." }, { "item_id": "N37", "question_type": "Evidence condition", "question": "Are boundaries involving dizziness and hyperventilation actual event tables?", "needed": "Harms definitions, collection and direct arm-specific data", "role": "Required", "role_reason": "This condition connects Harms definitions, collection and direct arm-specific data with populations, programs, actual controls, measures, timing, denominators, models, prespecification, direct effects/CIs or harms for nonclinical perceived stress, distinguishing other mental-symptom measures, biomarkers and treatment claims.", "application_exception": "Preserve original subclaim C, positive signals and no-intervention/prespecification/blinding gaps. Distinguish absent subclaim score/status/axes from parent C with 50 points, Unknown safety and unrecorded precision. Do not convert large F/P or partial-effect statistics to direct score differences, CIs, importance thresholds or laughter-specific effects. Do not transfer other measures, cortisol, video, brief exposure or original samples to the same PSS effects/denominators. Create no new effects, CIs, totals, independence/safety certification or yoga/medical instructions.", "criterion": "Material for Harms definitions, collection and direct arm-specific data must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.", "basis": "Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.", "condition_origin": "Internally applied conditions preserved for the existing subclaim. They do not establish preregistration, official-tool certification or completed content review.", "proposed_research": "Material needed: Arm-specific people and event counts, definitions, diagnoses, severity, active or spontaneous collection and missingness are unverified. This records needed materials; no new research was executed.", "current_reports": [ "R01", "R02", "R03", "R04" ], "existence": "Display information in the original parent stored summary is preserved. Public availability, acquisition and actual reading of detailed external material are separately unverified.", "acquired_read": "Stored summary read; external abstracts, full texts, registration, protocols, SAPs and support disclosures unread", "observation": "The original safety explanation notes insufficient arm-specific adverse-event and long-term safety numbers and boundaries involving hyperventilation, dizziness, abdominal pressure and pain. These are distinguished from actual reported-event tables.", "condition_status": "Partly verified", "status_reason": "The selected claim, parent material and reports are distinguished and transferred from the stored summary. Detailed original material is unverified and review of existing content remains incomplete. This does not establish completed clinical review or certification.", "missingness": "Arm-specific people and event counts, definitions, diagnoses, severity, active or spontaneous collection and missingness are unverified.", "uncertainty": "External original material is unread and review of existing content remains incomplete. Original grades, scores, axes, historical verification and independence statements are not treated as new verdicts or certification.", "review_date": null, "reading_status": "Full text not read · Stored summary read", "additional_material": "Arm-specific people and event counts, definitions, diagnoses, severity, active or spontaneous collection and missingness are unverified." }, { "item_id": "N38", "question_type": "Evidence condition", "question": "Are exposure, event, discontinuation and recovery times known?", "needed": "Arm-specific events, actual exposure and timing", "role": "Required", "role_reason": "This condition connects Arm-specific events, actual exposure and timing with populations, programs, actual controls, measures, timing, denominators, models, prespecification, direct effects/CIs or harms for nonclinical perceived stress, distinguishing other mental-symptom measures, biomarkers and treatment claims.", "application_exception": "Preserve original subclaim C, positive signals and no-intervention/prespecification/blinding gaps. Distinguish absent subclaim score/status/axes from parent C with 50 points, Unknown safety and unrecorded precision. Do not convert large F/P or partial-effect statistics to direct score differences, CIs, importance thresholds or laughter-specific effects. Do not transfer other measures, cortisol, video, brief exposure or original samples to the same PSS effects/denominators. Create no new effects, CIs, totals, independence/safety certification or yoga/medical instructions.", "criterion": "Material for Arm-specific events, actual exposure and timing must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.", "basis": "Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.", "condition_origin": "Internally applied conditions preserved for the existing subclaim. They do not establish preregistration, official-tool certification or completed content review.", "proposed_research": "Material needed: Arm-specific events and actual exposure, onset, recovery, discontinuation, re-exposure and follow-up times are unverified. This records needed materials; no new research was executed.", "current_reports": [ "R01", "R02", "R03", "R04" ], "existence": "Display information in the original parent stored summary is preserved. Public availability, acquisition and actual reading of detailed external material are separately unverified.", "acquired_read": "Stored summary read; external abstracts, full texts, registration, protocols, SAPs and support disclosures unread", "observation": "Observation periods for single and repeated programs are not converted into harms onset or recovery times.", "condition_status": "Unverified", "status_reason": "The selected claim, parent material and reports are distinguished and transferred from the stored summary. Detailed original material is unverified and review of existing content remains incomplete. This does not establish completed clinical review or certification.", "missingness": "Arm-specific events and actual exposure, onset, recovery, discontinuation, re-exposure and follow-up times are unverified.", "uncertainty": "External original material is unread and review of existing content remains incomplete. Original grades, scores, axes, historical verification and independence statements are not treated as new verdicts or certification.", "review_date": null, "reading_status": "Full text not read · Stored summary read", "additional_material": "Arm-specific events and actual exposure, onset, recovery, discontinuation, re-exposure and follow-up times are unverified." }, { "item_id": "N39", "question_type": "Evidence condition", "question": "Can harms rates and comparative risks be determined?", "needed": "Arm-specific events, people, time and valid denominators", "role": "Required", "role_reason": "This condition connects Arm-specific events, people, time and valid denominators with populations, programs, actual controls, measures, timing, denominators, models, prespecification, direct effects/CIs or harms for nonclinical perceived stress, distinguishing other mental-symptom measures, biomarkers and treatment claims.", "application_exception": "Preserve original subclaim C, positive signals and no-intervention/prespecification/blinding gaps. Distinguish absent subclaim score/status/axes from parent C with 50 points, Unknown safety and unrecorded precision. Do not convert large F/P or partial-effect statistics to direct score differences, CIs, importance thresholds or laughter-specific effects. Do not transfer other measures, cortisol, video, brief exposure or original samples to the same PSS effects/denominators. Create no new effects, CIs, totals, independence/safety certification or yoga/medical instructions.", "criterion": "Material for Arm-specific events, people, time and valid denominators must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.", "basis": "Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.", "condition_origin": "Internally applied conditions preserved for the existing subclaim. They do not establish preregistration, official-tool certification or completed content review.", "proposed_research": "Material needed: Arm-specific harms, people, event counts and duplicates, exposure, time, denominators, comparisons and confidence intervals are unverified. This records needed materials; no new research was executed.", "current_reports": [ "R01", "R02", "R03", "R04" ], "existence": "Display information in the original parent stored summary is preserved. Public availability, acquisition and actual reading of detailed external material are separately unverified.", "acquired_read": "Stored summary read; external abstracts, full texts, registration, protocols, SAPs and support disclosures unread", "observation": "Complete participation, analysis and total counts and large PSS statistics are not valid harms denominators or evidence of no events. No direct rates or comparative risks are calculated.", "condition_status": "Unverified", "status_reason": "The selected claim, parent material and reports are distinguished and transferred from the stored summary. Detailed original material is unverified and review of existing content remains incomplete. This does not establish completed clinical review or certification.", "missingness": "Arm-specific harms, people, event counts and duplicates, exposure, time, denominators, comparisons and confidence intervals are unverified.", "uncertainty": "External original material is unread and review of existing content remains incomplete. Original grades, scores, axes, historical verification and independence statements are not treated as new verdicts or certification.", "review_date": null, "reading_status": "Full text not read · Stored summary read", "additional_material": "Arm-specific harms, people, event counts and duplicates, exposure, time, denominators, comparisons and confidence intervals are unverified." }, { "item_id": "N40", "question_type": "Evidence condition", "question": "What about baseline conditions, concurrent activities and special populations?", "needed": "Population- and activity-specific harms and alternative causes", "role": "Required", "role_reason": "This condition connects Population- and activity-specific harms and alternative causes with populations, programs, actual controls, measures, timing, denominators, models, prespecification, direct effects/CIs or harms for nonclinical perceived stress, distinguishing other mental-symptom measures, biomarkers and treatment claims.", "application_exception": "Preserve original subclaim C, positive signals and no-intervention/prespecification/blinding gaps. Distinguish absent subclaim score/status/axes from parent C with 50 points, Unknown safety and unrecorded precision. Do not convert large F/P or partial-effect statistics to direct score differences, CIs, importance thresholds or laughter-specific effects. Do not transfer other measures, cortisol, video, brief exposure or original samples to the same PSS effects/denominators. Create no new effects, CIs, totals, independence/safety certification or yoga/medical instructions.", "criterion": "Material for Population- and activity-specific harms and alternative causes must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.", "basis": "Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.", "condition_origin": "Internally applied conditions preserved for the existing subclaim. They do not establish preregistration, official-tool certification or completed content review.", "proposed_research": "Material needed: Direct population- and activity-specific events, alternative causes, long-term, rare and vulnerable-population information and risk magnitude are unverified. This records needed materials; no new research was executed.", "current_reports": [ "R01", "R02", "R03", "R04" ], "existence": "Display information in the original parent stored summary is preserved. Public availability, acquisition and actual reading of detailed external material are separately unverified.", "acquired_read": "Stored summary read; external abstracts, full texts, registration, protocols, SAPs and support disclosures unread", "observation": "The original safety boundaries involving recent surgery, hernia and severe cardiopulmonary conditions are preserved in the internal original. No new medical or yoga practice instructions are created.", "condition_status": "Partly verified", "status_reason": "The selected claim, parent material and reports are distinguished and transferred from the stored summary. Detailed original material is unverified and review of existing content remains incomplete. This does not establish completed clinical review or certification.", "missingness": "Direct population- and activity-specific events, alternative causes, long-term, rare and vulnerable-population information and risk magnitude are unverified.", "uncertainty": "External original material is unread and review of existing content remains incomplete. Original grades, scores, axes, historical verification and independence statements are not treated as new verdicts or certification.", "review_date": null, "reading_status": "Full text not read · Stored summary read", "additional_material": "Direct population- and activity-specific events, alternative causes, long-term, rare and vulnerable-population information and risk magnitude are unverified." }, { "item_id": "N41", "question_type": "Evidence condition", "question": "Are shared reports summed as independent events?", "needed": "Overlap between reports, missingness, people and events", "role": "Required", "role_reason": "This condition connects Overlap between reports, missingness, people and events with populations, programs, actual controls, measures, timing, denominators, models, prespecification, direct effects/CIs or harms for nonclinical perceived stress, distinguishing other mental-symptom measures, biomarkers and treatment claims.", "application_exception": "Preserve original subclaim C, positive signals and no-intervention/prespecification/blinding gaps. Distinguish absent subclaim score/status/axes from parent C with 50 points, Unknown safety and unrecorded precision. Do not convert large F/P or partial-effect statistics to direct score differences, CIs, importance thresholds or laughter-specific effects. Do not transfer other measures, cortisol, video, brief exposure or original samples to the same PSS effects/denominators. Create no new effects, CIs, totals, independence/safety certification or yoga/medical instructions.", "criterion": "Material for Overlap between reports, missingness, people and events must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.", "basis": "Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.", "condition_origin": "Internally applied conditions preserved for the existing subclaim. They do not establish preregistration, official-tool certification or completed content review.", "proposed_research": "Material needed: Reporting, detection, selection, arm-specific losses, unique people, events and study families and the extent of all public data are unverified. This records needed materials; no new research was executed.", "current_reports": [ "R01", "R02", "R03", "R04" ], "existence": "Display information in the original parent stored summary is preserved. Public availability, acquisition and actual reading of detailed external material are separately unverified.", "acquired_read": "Stored summary read; external abstracts, full texts, registration, protocols, SAPs and support disclosures unread", "observation": "Sharing materials across Korean/English versions, parent and subclaims does not add independent events. Insufficient safety numbers are not converted into no events.", "condition_status": "Unverified", "status_reason": "The selected claim, parent material and reports are distinguished and transferred from the stored summary. Detailed original material is unverified and review of existing content remains incomplete. This does not establish completed clinical review or certification.", "missingness": "Reporting, detection, selection, arm-specific losses, unique people, events and study families and the extent of all public data are unverified.", "uncertainty": "External original material is unread and review of existing content remains incomplete. Original grades, scores, axes, historical verification and independence statements are not treated as new verdicts or certification.", "review_date": null, "reading_status": "Full text not read · Stored summary read", "additional_material": "Reporting, detection, selection, arm-specific losses, unique people, events and study families and the extent of all public data are unverified." }, { "item_id": "N42", "question_type": "Evidence condition", "question": "What do the signals and gaps establish?", "needed": "Direct PSS results and interpretation boundaries", "role": "Required", "role_reason": "This condition connects Direct PSS results and interpretation boundaries with populations, programs, actual controls, measures, timing, denominators, models, prespecification, direct effects/CIs or harms for nonclinical perceived stress, distinguishing other mental-symptom measures, biomarkers and treatment claims.", "application_exception": "Preserve original subclaim C, positive signals and no-intervention/prespecification/blinding gaps. Distinguish absent subclaim score/status/axes from parent C with 50 points, Unknown safety and unrecorded precision. Do not convert large F/P or partial-effect statistics to direct score differences, CIs, importance thresholds or laughter-specific effects. Do not transfer other measures, cortisol, video, brief exposure or original samples to the same PSS effects/denominators. Create no new effects, CIs, totals, independence/safety certification or yoga/medical instructions.", "criterion": "Material for Direct PSS results and interpretation boundaries must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.", "basis": "Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.", "condition_origin": "Internally applied conditions preserved for the existing subclaim. They do not establish preregistration, official-tool certification or completed content review.", "proposed_research": "Material needed: Direct PSS effects and confidence intervals, active social controls, prespecification, models, denominators, long-term outcomes and harms data remain needed. This records needed materials; no new research was executed.", "current_reports": [ "R01", "R02", "R03", "R04" ], "existence": "Display information in the original parent stored summary is preserved. Public availability, acquisition and actual reading of detailed external material are separately unverified.", "acquired_read": "Stored summary read; external abstracts, full texts, registration, protocols, SAPs and support disclosures unread", "observation": "Signals and gaps in existing selected C are retained. No new laughter-specific effect, cortisol normalization, depression/anxiety treatment claim or independent confirmation is created.", "condition_status": "Partly verified", "status_reason": "The selected claim, parent material and reports are distinguished and transferred from the stored summary. Detailed original material is unverified and review of existing content remains incomplete. This does not establish completed clinical review or certification.", "missingness": "Direct PSS effects and confidence intervals, active social controls, prespecification, models, denominators, long-term outcomes and harms data remain needed.", "uncertainty": "External original material is unread and review of existing content remains incomplete. Original grades, scores, axes, historical verification and independence statements are not treated as new verdicts or certification.", "review_date": null, "reading_status": "Full text not read · Stored summary read", "additional_material": "Direct PSS effects and confidence intervals, active social controls, prespecification, models, denominators, long-term outcomes and harms data remain needed." }, { "item_id": "N43", "question_type": "Evidence condition", "question": "Does linking methods documents complete content review?", "needed": "Production methodology materials and review status", "role": "Required", "role_reason": "This condition connects Production methodology materials and review status with populations, programs, actual controls, measures, timing, denominators, models, prespecification, direct effects/CIs or harms for nonclinical perceived stress, distinguishing other mental-symptom measures, biomarkers and treatment claims.", "application_exception": "Preserve original subclaim C, positive signals and no-intervention/prespecification/blinding gaps. Distinguish absent subclaim score/status/axes from parent C with 50 points, Unknown safety and unrecorded precision. Do not convert large F/P or partial-effect statistics to direct score differences, CIs, importance thresholds or laughter-specific effects. Do not transfer other measures, cortisol, video, brief exposure or original samples to the same PSS effects/denominators. Create no new effects, CIs, totals, independence/safety certification or yoga/medical instructions.", "criterion": "Material for Production methodology materials and review status must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.", "basis": "Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.", "condition_origin": "Internally applied conditions preserved for the existing subclaim. They do not establish preregistration, official-tool certification or completed content review.", "proposed_research": "Material needed: Individual methods and external content review and quality testing were not performed; the existing pending-review state is retained. This records needed materials; no new research was executed.", "current_reports": [ "R01", "R02", "R03", "R04" ], "existence": "Display information in the original parent stored summary is preserved. Public availability, acquisition and actual reading of detailed external material are separately unverified.", "acquired_read": "Stored summary read; external abstracts, full texts, registration, protocols, SAPs and support disclosures unread", "observation": "Preserved methods, study-family and quality-rule documents are production copies. Linking them alone does not complete new clinical or methods review or approval.", "condition_status": "Partly verified", "status_reason": "The selected claim, parent material and reports are distinguished and transferred from the stored summary. Detailed original material is unverified and review of existing content remains incomplete. This does not establish completed clinical review or certification.", "missingness": "Individual methods and external content review and quality testing were not performed; the existing pending-review state is retained.", "uncertainty": "External original material is unread and review of existing content remains incomplete. Original grades, scores, axes, historical verification and independence statements are not treated as new verdicts or certification.", "review_date": null, "reading_status": "Full text not read · Stored summary read", "additional_material": "Individual methods and external content review and quality testing were not performed; the existing pending-review state is retained." }, { "item_id": "N44", "question_type": "Evidence condition", "question": "What materials would update these gaps?", "needed": "Direct results, analysis plans, overlap and harms data", "role": "Required", "role_reason": "This condition connects Direct results, analysis plans, overlap and harms data with populations, programs, actual controls, measures, timing, denominators, models, prespecification, direct effects/CIs or harms for nonclinical perceived stress, distinguishing other mental-symptom measures, biomarkers and treatment claims.", "application_exception": "Preserve original subclaim C, positive signals and no-intervention/prespecification/blinding gaps. Distinguish absent subclaim score/status/axes from parent C with 50 points, Unknown safety and unrecorded precision. Do not convert large F/P or partial-effect statistics to direct score differences, CIs, importance thresholds or laughter-specific effects. Do not transfer other measures, cortisol, video, brief exposure or original samples to the same PSS effects/denominators. Create no new effects, CIs, totals, independence/safety certification or yoga/medical instructions.", "criterion": "Material for Direct results, analysis plans, overlap and harms data must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.", "basis": "Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.", "condition_origin": "Internally applied conditions preserved for the existing subclaim. They do not establish preregistration, official-tool certification or completed content review.", "proposed_research": "Material needed: Direct PSS tables, estimates and confidence intervals, conflicting tests and models, active controls, schedules, registration, study overlap and exposure and harms materials are needed. This records needed materials; no new research was executed.", "current_reports": [ "R01", "R02", "R03", "R04" ], "existence": "Display information in the original parent stored summary is preserved. Public availability, acquisition and actual reading of detailed external material are separately unverified.", "acquired_read": "Stored summary read; external abstracts, full texts, registration, protocols, SAPs and support disclosures unread", "observation": "This reader view distinguishes original signals, conflicting statements and gaps from parent context. The existing pending content-review state remains; no new verdict was made.", "condition_status": "Partly verified", "status_reason": "The selected claim, parent material and reports are distinguished and transferred from the stored summary. Detailed original material is unverified and review of existing content remains incomplete. This does not establish completed clinical review or certification.", "missingness": "Direct PSS tables, estimates and confidence intervals, conflicting tests and models, active controls, schedules, registration, study overlap and exposure and harms materials are needed.", "uncertainty": "External original material is unread and review of existing content remains incomplete. Original grades, scores, axes, historical verification and independence statements are not treated as new verdicts or certification.", "review_date": null, "reading_status": "Full text not read · Stored summary read", "additional_material": "Direct PSS tables, estimates and confidence intervals, conflicting tests and models, active controls, schedules, registration, study overlap and exposure and harms materials are needed." } ], "reports": [ { "report_id": "R01", "title": "Bilgihan S, Dost A. The effect of laughter yoga on the general health status, perceived stress and burnout levels of psychiatric nurses: a randomized controlled study. Discover Psychology. 2026;6:200. DOI: 10.1007/s44202-026-00725-4.", "url": "https://doi.org/10.1007/s44202-026-00725-4", "report_type": "Randomized controlled trial", "existence": "The stored summary contains a bibliography; acquisition and reading of external originals are unverified.", "acquired_read": "Stored summary read; external materials unread", "study_family": "Original report shared across parent/subclaims; unique counts and independence unverified", "independent_replication": "The parent and perceived-stress, other mental-symptom and cortisol questions share four original reports. Preserve report-specific groups and sharing, but exact registration/recruitment/population relationships and unique-trial/participant/event totals remain unverified. Do not add arms, sessions or other sheets as new independent replication.", "observed_result": "PSS group-by-time F(1,68)=251.56, P<.001, partial eta-squared .787; trial and registration dates raised timing concerns", "result_level": "PSS group-by-time context in 70 participants, 35 versus 35, all completed. Preserve no-intervention controls, combined instructor/assessor role and trial/registration-timing concerns. Do not turn large statistics into direct score differences/CIs, clinical importance or laughter-specific effects.", "source_evidence_date": "2026-09-07", "materials": [ { "material_type": "Stored existing review summary", "public_status": "Preserved copy of the complete parent-verdict stored summary", "access_status": "Stored summary", "acquired": true, "actually_read": "Summary read", "as_of": "2026-09-07", "qualification": "Preserve original DOI 10.1007/s44202-026-00725-4, NCT07015372 and trial/registration-timing concerns. PMID/PMCID are unrecorded. Identifiers, bibliography and no-external-funding/COI statements do not establish current full-text/registration reading or independence certification." }, { "material_type": "External abstract", "public_status": "Original bibliographic link or needed material; external public availability/access status unverified", "access_status": "Unread; access not attempted", "acquired": false, "actually_read": "Not read", "as_of": "2026-09-07", "qualification": "Preserve original DOI 10.1007/s44202-026-00725-4, NCT07015372 and trial/registration-timing concerns. PMID/PMCID are unrecorded. Identifiers, bibliography and no-external-funding/COI statements do not establish current full-text/registration reading or independence certification." }, { "material_type": "External full text", "public_status": "Original bibliographic link or needed material; external public availability/access status unverified", "access_status": "Unread; access not attempted", "acquired": false, "actually_read": "Not read", "as_of": "2026-09-07", "qualification": "Preserve original DOI 10.1007/s44202-026-00725-4, NCT07015372 and trial/registration-timing concerns. PMID/PMCID are unrecorded. Identifiers, bibliography and no-external-funding/COI statements do not establish current full-text/registration reading or independence certification." }, { "material_type": "Registration material", "public_status": "Original bibliographic link or needed material; external public availability/access status unverified", "access_status": "Unread; access not attempted", "acquired": false, "actually_read": "Not read", "as_of": "2026-09-07", "qualification": "Preserve original DOI 10.1007/s44202-026-00725-4, NCT07015372 and trial/registration-timing concerns. PMID/PMCID are unrecorded. Identifiers, bibliography and no-external-funding/COI statements do not establish current full-text/registration reading or independence certification." }, { "material_type": "Protocol", "public_status": "Original bibliographic link or needed material; external public availability/access status unverified", "access_status": "Unread; access not attempted", "acquired": false, "actually_read": "Not read", "as_of": "2026-09-07", "qualification": "Preserve original DOI 10.1007/s44202-026-00725-4, NCT07015372 and trial/registration-timing concerns. PMID/PMCID are unrecorded. Identifiers, bibliography and no-external-funding/COI statements do not establish current full-text/registration reading or independence certification." }, { "material_type": "Analysis plan, measures and denominators", "public_status": "Original bibliographic link or needed material; external public availability/access status unverified", "access_status": "Unread; access not attempted", "acquired": false, "actually_read": "Not read", "as_of": "2026-09-07", "qualification": "Preserve original DOI 10.1007/s44202-026-00725-4, NCT07015372 and trial/registration-timing concerns. PMID/PMCID are unrecorded. Identifiers, bibliography and no-external-funding/COI statements do not establish current full-text/registration reading or independence certification." }, { "material_type": "Exposure, comparators and harms", "public_status": "Original bibliographic link or needed material; external public availability/access status unverified", "access_status": "Unread; access not attempted", "acquired": false, "actually_read": "Not read", "as_of": "2026-09-07", "qualification": "Preserve original DOI 10.1007/s44202-026-00725-4, NCT07015372 and trial/registration-timing concerns. PMID/PMCID are unrecorded. Identifiers, bibliography and no-external-funding/COI statements do not establish current full-text/registration reading or independence certification." }, { "material_type": "Support and interests", "public_status": "Original bibliographic link or needed material; external public availability/access status unverified", "access_status": "Unread; access not attempted", "acquired": false, "actually_read": "Not read", "as_of": "2026-09-07", "qualification": "Preserve original DOI 10.1007/s44202-026-00725-4, NCT07015372 and trial/registration-timing concerns. PMID/PMCID are unrecorded. Identifiers, bibliography and no-external-funding/COI statements do not establish current full-text/registration reading or independence certification." } ], "links": [ { "label": "Official source", "url": "https://doi.org/10.1007/s44202-026-00725-4" } ] }, { "report_id": "R02", "title": "Yaş MA, et al. The effect of laughter yoga on well-being, perceived stress, and academic self-efficacy in nursing students: A randomized controlled trial. Appl Psychol Health Well Being. 2025;17:e12610. PMID: 39415513. PMCID: PMC11635907. DOI: 10.1111/aphw.12610.", "url": "https://pubmed.ncbi.nlm.nih.gov/39415513/", "report_type": "Randomized controlled trial", "existence": "The stored summary contains a bibliography; acquisition and reading of external originals are unverified.", "acquired_read": "Stored summary read; external materials unread", "study_family": "Original report shared across parent/subclaims; unique counts and independence unverified", "independent_replication": "The parent and perceived-stress, other mental-symptom and cortisol questions share four original reports. Preserve report-specific groups and sharing, but exact registration/recruitment/population relationships and unique-trial/participant/event totals remain unverified. Do not add arms, sessions or other sheets as new independent replication.", "observed_result": "A null between-group abstract statement coexisted with a multivariate interaction F=10.69, P<.001; registration was retrospective", "result_level": "83 analyzed participants, 41 versus 42. Preserve the original coexistence of a null between-group abstract statement and main-text multivariate interaction, plus retrospective registration. Individual tests, PSS-specific effects/CIs and denominators are unverified; no new original-text comparison or conflict resolution occurred.", "source_evidence_date": "2026-09-07", "materials": [ { "material_type": "Stored existing review summary", "public_status": "Preserved copy of the complete parent-verdict stored summary", "access_status": "Stored summary", "acquired": true, "actually_read": "Summary read", "as_of": "2026-09-07", "qualification": "Preserve original PMID 39415513, PMCID PMC11635907, DOI 10.1111/aphw.12610, NCT06175936, retrospective registration and coexisting statistical descriptions. Original registration content, exact PSS effects/CIs and support are unverified; no original-text comparison occurred now." }, { "material_type": "External abstract", "public_status": "Original bibliographic link or needed material; external public availability/access status unverified", "access_status": "Unread; access not attempted", "acquired": false, "actually_read": "Not read", "as_of": "2026-09-07", "qualification": "Preserve original PMID 39415513, PMCID PMC11635907, DOI 10.1111/aphw.12610, NCT06175936, retrospective registration and coexisting statistical descriptions. Original registration content, exact PSS effects/CIs and support are unverified; no original-text comparison occurred now." }, { "material_type": "External full text", "public_status": "Original bibliographic link or needed material; external public availability/access status unverified", "access_status": "Unread; access not attempted", "acquired": false, "actually_read": "Not read", "as_of": "2026-09-07", "qualification": "Preserve original PMID 39415513, PMCID PMC11635907, DOI 10.1111/aphw.12610, NCT06175936, retrospective registration and coexisting statistical descriptions. Original registration content, exact PSS effects/CIs and support are unverified; no original-text comparison occurred now." }, { "material_type": "Registration material", "public_status": "Original bibliographic link or needed material; external public availability/access status unverified", "access_status": "Unread; access not attempted", "acquired": false, "actually_read": "Not read", "as_of": "2026-09-07", "qualification": "Preserve original PMID 39415513, PMCID PMC11635907, DOI 10.1111/aphw.12610, NCT06175936, retrospective registration and coexisting statistical descriptions. Original registration content, exact PSS effects/CIs and support are unverified; no original-text comparison occurred now." }, { "material_type": "Protocol", "public_status": "Original bibliographic link or needed material; external public availability/access status unverified", "access_status": "Unread; access not attempted", "acquired": false, "actually_read": "Not read", "as_of": "2026-09-07", "qualification": "Preserve original PMID 39415513, PMCID PMC11635907, DOI 10.1111/aphw.12610, NCT06175936, retrospective registration and coexisting statistical descriptions. Original registration content, exact PSS effects/CIs and support are unverified; no original-text comparison occurred now." }, { "material_type": "Analysis plan, measures and denominators", "public_status": "Original bibliographic link or needed material; external public availability/access status unverified", "access_status": "Unread; access not attempted", "acquired": false, "actually_read": "Not read", "as_of": "2026-09-07", "qualification": "Preserve original PMID 39415513, PMCID PMC11635907, DOI 10.1111/aphw.12610, NCT06175936, retrospective registration and coexisting statistical descriptions. Original registration content, exact PSS effects/CIs and support are unverified; no original-text comparison occurred now." }, { "material_type": "Exposure, comparators and harms", "public_status": "Original bibliographic link or needed material; external public availability/access status unverified", "access_status": "Unread; access not attempted", "acquired": false, "actually_read": "Not read", "as_of": "2026-09-07", "qualification": "Preserve original PMID 39415513, PMCID PMC11635907, DOI 10.1111/aphw.12610, NCT06175936, retrospective registration and coexisting statistical descriptions. Original registration content, exact PSS effects/CIs and support are unverified; no original-text comparison occurred now." }, { "material_type": "Support and interests", "public_status": "Original bibliographic link or needed material; external public availability/access status unverified", "access_status": "Unread; access not attempted", "acquired": false, "actually_read": "Not read", "as_of": "2026-09-07", "qualification": "Preserve original PMID 39415513, PMCID PMC11635907, DOI 10.1111/aphw.12610, NCT06175936, retrospective registration and coexisting statistical descriptions. Original registration content, exact PSS effects/CIs and support are unverified; no original-text comparison occurred now." } ], "links": [ { "label": "PubMed", "url": "https://pubmed.ncbi.nlm.nih.gov/39415513/" } ] }, { "report_id": "R03", "title": "Ozturk FO, Tezel A. Effect of laughter yoga on mental symptoms and salivary cortisol levels in first-year nursing students: A randomized controlled trial. Int J Nurs Pract. 2021;27:e12924. PMID: 33580606. DOI: 10.1111/ijn.12924.", "url": "https://pubmed.ncbi.nlm.nih.gov/33580606/", "report_type": "Eight-session randomized controlled trial", "existence": "The stored summary contains a bibliography; acquisition and reading of external originals are unverified.", "acquired_read": "Stored summary read; external materials unread", "study_family": "Original report shared across parent/subclaims; unique counts and independence unverified", "independent_replication": "The parent and perceived-stress, other mental-symptom and cortisol questions share four original reports. Preserve report-specific groups and sharing, but exact registration/recruitment/population relationships and unique-trial/participant/event totals remain unverified. Do not add arms, sessions or other sheets as new independent replication.", "observed_result": "Mental symptoms favored intervention; cortisol was between-group positive in only 3 of 8 sessions", "result_level": "Mental-symptom/cortisol context from 8 sessions in 75 first-year nursing students. Direct PSS measurement/values, arm/session denominators, plans and intervals are unverified. Do not transfer mental symptoms or session-level biomarkers to the same perceived-stress effect.", "source_evidence_date": "2026-09-07", "materials": [ { "material_type": "Stored existing review summary", "public_status": "Preserved copy of the complete parent-verdict stored summary", "access_status": "Stored summary", "acquired": true, "actually_read": "Summary read", "as_of": "2026-09-07", "qualification": "Preserve original PMID 33580606 and DOI 10.1111/ijn.12924. PMCID is unrecorded; registration/support are unverified. Do not turn mental-symptom/session-level cortisol summaries into original PSS results or current full-text reading." }, { "material_type": "External abstract", "public_status": "Original bibliographic link or needed material; external public availability/access status unverified", "access_status": "Unread; access not attempted", "acquired": false, "actually_read": "Not read", "as_of": "2026-09-07", "qualification": "Preserve original PMID 33580606 and DOI 10.1111/ijn.12924. PMCID is unrecorded; registration/support are unverified. Do not turn mental-symptom/session-level cortisol summaries into original PSS results or current full-text reading." }, { "material_type": "External full text", "public_status": "Original bibliographic link or needed material; external public availability/access status unverified", "access_status": "Unread; access not attempted", "acquired": false, "actually_read": "Not read", "as_of": "2026-09-07", "qualification": "Preserve original PMID 33580606 and DOI 10.1111/ijn.12924. PMCID is unrecorded; registration/support are unverified. Do not turn mental-symptom/session-level cortisol summaries into original PSS results or current full-text reading." }, { "material_type": "Registration material", "public_status": "Original bibliographic link or needed material; external public availability/access status unverified", "access_status": "Unread; access not attempted", "acquired": false, "actually_read": "Not read", "as_of": "2026-09-07", "qualification": "Preserve original PMID 33580606 and DOI 10.1111/ijn.12924. PMCID is unrecorded; registration/support are unverified. Do not turn mental-symptom/session-level cortisol summaries into original PSS results or current full-text reading." }, { "material_type": "Protocol", "public_status": "Original bibliographic link or needed material; external public availability/access status unverified", "access_status": "Unread; access not attempted", "acquired": false, "actually_read": "Not read", "as_of": "2026-09-07", "qualification": "Preserve original PMID 33580606 and DOI 10.1111/ijn.12924. PMCID is unrecorded; registration/support are unverified. Do not turn mental-symptom/session-level cortisol summaries into original PSS results or current full-text reading." }, { "material_type": "Analysis plan, measures and denominators", "public_status": "Original bibliographic link or needed material; external public availability/access status unverified", "access_status": "Unread; access not attempted", "acquired": false, "actually_read": "Not read", "as_of": "2026-09-07", "qualification": "Preserve original PMID 33580606 and DOI 10.1111/ijn.12924. PMCID is unrecorded; registration/support are unverified. Do not turn mental-symptom/session-level cortisol summaries into original PSS results or current full-text reading." }, { "material_type": "Exposure, comparators and harms", "public_status": "Original bibliographic link or needed material; external public availability/access status unverified", "access_status": "Unread; access not attempted", "acquired": false, "actually_read": "Not read", "as_of": "2026-09-07", "qualification": "Preserve original PMID 33580606 and DOI 10.1111/ijn.12924. PMCID is unrecorded; registration/support are unverified. Do not turn mental-symptom/session-level cortisol summaries into original PSS results or current full-text reading." }, { "material_type": "Support and interests", "public_status": "Original bibliographic link or needed material; external public availability/access status unverified", "access_status": "Unread; access not attempted", "acquired": false, "actually_read": "Not read", "as_of": "2026-09-07", "qualification": "Preserve original PMID 33580606 and DOI 10.1111/ijn.12924. PMCID is unrecorded; registration/support are unverified. Do not turn mental-symptom/session-level cortisol summaries into original PSS results or current full-text reading." } ], "links": [ { "label": "PubMed", "url": "https://pubmed.ncbi.nlm.nih.gov/33580606/" } ] }, { "report_id": "R04", "title": "Fujisawa A, et al. Effect of laughter yoga on salivary cortisol and dehydroepiandrosterone among healthy university students: A randomized controlled trial. Complement Ther Clin Pract. 2018;32:6-11. PMID: 30057059. DOI: 10.1016/j.ctcp.2018.04.005.", "url": "https://pubmed.ncbi.nlm.nih.gov/30057059/", "report_type": "Three-arm laughter-yoga, humorous-video, and reading randomized trial", "existence": "The stored summary contains a bibliography; acquisition and reading of external originals are unverified.", "acquired_read": "Stored summary read; external materials unread", "study_family": "Original report shared across parent/subclaims; unique counts and independence unverified", "independent_replication": "The parent and perceived-stress, other mental-symptom and cortisol questions share four original reports. Preserve report-specific groups and sharing, but exact registration/recruitment/population relationships and unique-trial/participant/event totals remain unverified. Do not add arms, sessions or other sheets as new independent replication.", "observed_result": "Cortisol changed over time, humorous video also changed it, and DHEA was null", "result_level": "Acute 3-arm cortisol/DHEA context in 120 healthy university students. Video is a separate intervention; direct PSS measurement/effects, arm denominators, exact comparative CIs and long-term effects are unverified.", "source_evidence_date": "2026-09-07", "materials": [ { "material_type": "Stored existing review summary", "public_status": "Preserved copy of the complete parent-verdict stored summary", "access_status": "Stored summary", "acquired": true, "actually_read": "Summary read", "as_of": "2026-09-07", "qualification": "Preserve original PMID 30057059, DOI 10.1016/j.ctcp.2018.04.005 and UMIN000019409. PMCID is unrecorded; support and exact comparative CIs are unverified. Do not relabel UMIN as NCT or treat the identifier as current registration-content verification." }, { "material_type": "External abstract", "public_status": "Original bibliographic link or needed material; external public availability/access status unverified", "access_status": "Unread; access not attempted", "acquired": false, "actually_read": "Not read", "as_of": "2026-09-07", "qualification": "Preserve original PMID 30057059, DOI 10.1016/j.ctcp.2018.04.005 and UMIN000019409. PMCID is unrecorded; support and exact comparative CIs are unverified. Do not relabel UMIN as NCT or treat the identifier as current registration-content verification." }, { "material_type": "External full text", "public_status": "Original bibliographic link or needed material; external public availability/access status unverified", "access_status": "Unread; access not attempted", "acquired": false, "actually_read": "Not read", "as_of": "2026-09-07", "qualification": "Preserve original PMID 30057059, DOI 10.1016/j.ctcp.2018.04.005 and UMIN000019409. PMCID is unrecorded; support and exact comparative CIs are unverified. Do not relabel UMIN as NCT or treat the identifier as current registration-content verification." }, { "material_type": "Registration material", "public_status": "Original bibliographic link or needed material; external public availability/access status unverified", "access_status": "Unread; access not attempted", "acquired": false, "actually_read": "Not read", "as_of": "2026-09-07", "qualification": "Preserve original PMID 30057059, DOI 10.1016/j.ctcp.2018.04.005 and UMIN000019409. PMCID is unrecorded; support and exact comparative CIs are unverified. Do not relabel UMIN as NCT or treat the identifier as current registration-content verification." }, { "material_type": "Protocol", "public_status": "Original bibliographic link or needed material; external public availability/access status unverified", "access_status": "Unread; access not attempted", "acquired": false, "actually_read": "Not read", "as_of": "2026-09-07", "qualification": "Preserve original PMID 30057059, DOI 10.1016/j.ctcp.2018.04.005 and UMIN000019409. PMCID is unrecorded; support and exact comparative CIs are unverified. Do not relabel UMIN as NCT or treat the identifier as current registration-content verification." }, { "material_type": "Analysis plan, measures and denominators", "public_status": "Original bibliographic link or needed material; external public availability/access status unverified", "access_status": "Unread; access not attempted", "acquired": false, "actually_read": "Not read", "as_of": "2026-09-07", "qualification": "Preserve original PMID 30057059, DOI 10.1016/j.ctcp.2018.04.005 and UMIN000019409. PMCID is unrecorded; support and exact comparative CIs are unverified. Do not relabel UMIN as NCT or treat the identifier as current registration-content verification." }, { "material_type": "Exposure, comparators and harms", "public_status": "Original bibliographic link or needed material; external public availability/access status unverified", "access_status": "Unread; access not attempted", "acquired": false, "actually_read": "Not read", "as_of": "2026-09-07", "qualification": "Preserve original PMID 30057059, DOI 10.1016/j.ctcp.2018.04.005 and UMIN000019409. PMCID is unrecorded; support and exact comparative CIs are unverified. Do not relabel UMIN as NCT or treat the identifier as current registration-content verification." }, { "material_type": "Support and interests", "public_status": "Original bibliographic link or needed material; external public availability/access status unverified", "access_status": "Unread; access not attempted", "acquired": false, "actually_read": "Not read", "as_of": "2026-09-07", "qualification": "Preserve original PMID 30057059, DOI 10.1016/j.ctcp.2018.04.005 and UMIN000019409. PMCID is unrecorded; support and exact comparative CIs are unverified. Do not relabel UMIN as NCT or treat the identifier as current registration-content verification." } ], "links": [ { "label": "PubMed", "url": "https://pubmed.ncbi.nlm.nih.gov/30057059/" } ] } ], "method_sources": [ { "id": "M03", "version": "Cochrane Handbook 6.5 (2024), chapter updated 2023-08", "url": "https://www.cochrane.org/authors/handbooks-and-manuals/handbook/current/chapter-03", "section": "§3.1, §3.2.1–3.2.3, MECIR C5/C7/C13", "official_principle": "Clearly record the question, eligibility conditions and reasons for changes, and distinguish variations in interventions.", "review_level": "Existing methodological links were reused for production. External originals were not reread and methodological content was not reassessed." }, { "id": "M04", "version": "Cochrane Handbook 6.5.1 (2025), chapter updated 2025-03", "url": "https://www.cochrane.org/authors/handbooks-and-manuals/handbook/current/chapter-04", "section": "§4.5, §4.6.1–4.6.3, MECIR C42", "official_principle": "Distinguish studies from reports and link them; do not omit a study solely because results are unreported.", "review_level": "Existing methodological links were reused for production. External originals were not reread and methodological content was not reassessed." }, { "id": "M08", "version": "Cochrane Handbook 6.5 (2024), chapter updated 2019-10", "url": "https://www.cochrane.org/authors/handbooks-and-manuals/handbook/current/chapter-08", "section": "§8.1–8.2.3, Table 8.2.a", "official_principle": "Define the outcome and effect of interest, then examine randomization, deviations, missing data, measurement and selective reporting.", "review_level": "Existing methodological links were reused for production. External originals were not reread and methodological content was not reassessed." }, { "id": "M15", "version": "Cochrane Handbook 6.5 (2024), chapter updated 2023-08", "url": "https://www.cochrane.org/authors/handbooks-and-manuals/handbook/current/chapter-15", "section": "§15.2.4, §15.3.1–15.3.3", "official_principle": "Distinguish effect estimates, intervals, importance and applicability. Sample size alone does not determine precision.", "review_level": "Existing methodological links were reused for production. External originals were not reread and methodological content was not reassessed." }, { "id": "M19", "version": "Cochrane Handbook 6.5 (2024), chapter updated 2019-10", "url": "https://www.cochrane.org/authors/handbooks-and-manuals/handbook/current/chapter-19", "section": "§19.1.2, §19.2.1–19.2.4", "official_principle": "Harm questions may require different designs, populations and follow-up from efficacy questions. Case reports do not establish incidence rates.", "review_level": "Existing methodological links were reused for production. External originals were not reread and methodological content was not reassessed." } ], "status_dictionary": { "Met": "Condition confirmed through user review; not used in this production", "Partly verified": "Partly recorded in preserved selected/parent summaries; selected-measure details, external verification and user review remain incomplete", "Unverified": "Exact values, denominators, procedures and harms are not established; this does not assert that all external materials omit them", "Review incomplete": "Content review pending; no individual content review or testing was performed in this production", "Not reported": "Limited to materials actually read; not a substitute for unread external materials", "Inaccessible": "Only for actual new access failures; distinct from unattempted access and historical narratives", "Insufficient evidence for the conditions": "Original selected-measure details and precision gaps; not a new grade", "Not applicable": "Only with an explicit question- or design-based reason", "Conflicting data": "Only when actual new conflicting materials are compared; this work preserves the original historical conflict narrative without content review" }, "study_overlap": { "state": "Unverified", "unique_trial_count": null, "unique_participant_count": null, "reason": "The parent and perceived-stress, other mental-symptom and cortisol questions share four original reports. Preserve report-specific groups and sharing, but exact registration/recruitment/population relationships and unique-trial/participant/event totals remain unverified. Do not add arms, sessions or other sheets as new independent replication." }, "history": [ { "date": "2026-10-19", "kind": "Separation of public-facing pages and materials", "view_version": "1.0", "change": "A public view and materials were prepared from the existing 44 items. No new clinical search, verification-status change or scoring was performed." } ], "language": "en", "translation_date": "2026-10-19" }