{ "schema_version": "chamgap-public-criteria-1.0", "title": "Laughter Yoga for Perceived Stress—Improvement Signal With Unclear Prespecification and Controls", "language": "en", "translation_date": "2026-10-19", "criteria_version": "1.0", "criteria_date": "2026-10-06", "condition_origin": "Chamgap's own application conditions", "method_sources": [ { "id": "M03", "version": "Cochrane Handbook 6.5 (2024), chapter updated 2023-08", "url": "https://www.cochrane.org/authors/handbooks-and-manuals/handbook/current/chapter-03", "section": "§3.1, §3.2.1–3.2.3, MECIR C5/C7/C13", "official_principle": "Clearly record the question, eligibility conditions and reasons for changes, and distinguish variations in interventions.", "review_level": "Existing methodological links were reused for production. External originals were not reread and methodological content was not reassessed." }, { "id": "M04", "version": "Cochrane Handbook 6.5.1 (2025), chapter updated 2025-03", "url": "https://www.cochrane.org/authors/handbooks-and-manuals/handbook/current/chapter-04", "section": "§4.5, §4.6.1–4.6.3, MECIR C42", "official_principle": "Distinguish studies from reports and link them; do not omit a study solely because results are unreported.", "review_level": "Existing methodological links were reused for production. External originals were not reread and methodological content was not reassessed." }, { "id": "M08", "version": "Cochrane Handbook 6.5 (2024), chapter updated 2019-10", "url": "https://www.cochrane.org/authors/handbooks-and-manuals/handbook/current/chapter-08", "section": "§8.1–8.2.3, Table 8.2.a", "official_principle": "Define the outcome and effect of interest, then examine randomization, deviations, missing data, measurement and selective reporting.", "review_level": "Existing methodological links were reused for production. External originals were not reread and methodological content was not reassessed." }, { "id": "M15", "version": "Cochrane Handbook 6.5 (2024), chapter updated 2023-08", "url": "https://www.cochrane.org/authors/handbooks-and-manuals/handbook/current/chapter-15", "section": "§15.2.4, §15.3.1–15.3.3", "official_principle": "Distinguish effect estimates, intervals, importance and applicability. Sample size alone does not determine precision.", "review_level": "Existing methodological links were reused for production. External originals were not reread and methodological content was not reassessed." }, { "id": "M19", "version": "Cochrane Handbook 6.5 (2024), chapter updated 2019-10", "url": "https://www.cochrane.org/authors/handbooks-and-manuals/handbook/current/chapter-19", "section": "§19.1.2, §19.2.1–19.2.4", "official_principle": "Harm questions may require different designs, populations and follow-up from efficacy questions. Case reports do not establish incidence rates.", "review_level": "Existing methodological links were reused for production. External originals were not reread and methodological content was not reassessed." } ], "status_dictionary": { "Met": "Condition confirmed through user review; not used in this production", "Partly verified": "Partly recorded in preserved selected/parent summaries; selected-measure details, external verification and user review remain incomplete", "Unverified": "Exact values, denominators, procedures and harms are not established; this does not assert that all external materials omit them", "Review incomplete": "Content review pending; no individual content review or testing was performed in this production", "Not reported": "Limited to materials actually read; not a substitute for unread external materials", "Inaccessible": "Only for actual new access failures; distinct from unattempted access and historical narratives", "Insufficient evidence for the conditions": "Original selected-measure details and precision gaps; not a new grade", "Not applicable": "Only with an explicit question- or design-based reason", "Conflicting data": "Only when actual new conflicting materials are compared; this work preserves the original historical conflict narrative without content review" }, "requirements": [ { "item_id": "N01", "question_type": "Evidence condition", "question": "Which question is covered?", "needed": "The selected subclaim's population and outcome", "role": "Required", "role_reason": "This condition connects The selected subclaim's population and outcome with populations, programs, actual controls, measures, timing, denominators, models, prespecification, direct effects/CIs or harms for nonclinical perceived stress, distinguishing other mental-symptom measures, biomarkers and treatment claims.", "application_exception": "Preserve original subclaim C, positive signals and no-intervention/prespecification/blinding gaps. Distinguish absent subclaim score/status/axes from parent C with 50 points, Unknown safety and unrecorded precision. Do not convert large F/P or partial-effect statistics to direct score differences, CIs, importance thresholds or laughter-specific effects. Do not transfer other measures, cortisol, video, brief exposure or original samples to the same PSS effects/denominators. Create no new effects, CIs, totals, independence/safety certification or yoga/medical instructions.", "criterion": "Material for The selected subclaim's population and outcome must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.", "basis": "Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.", "condition_origin": "Internally applied conditions preserved for the existing subclaim. They do not establish preregistration, official-tool certification or completed content review.", "proposed_research": "Material needed: Individual content review and independent verification of the population and outcome boundaries remain incomplete. This records needed materials; no new research was executed." }, { "item_id": "N02", "question_type": "Evidence condition", "question": "How does selected grade C differ from the parent verdict?", "needed": "The scope of the selected grade and overall verdict", "role": "Required", "role_reason": "This condition connects The scope of the selected grade and overall verdict with populations, programs, actual controls, measures, timing, denominators, models, prespecification, direct effects/CIs or harms for nonclinical perceived stress, distinguishing other mental-symptom measures, biomarkers and treatment claims.", "application_exception": "Preserve original subclaim C, positive signals and no-intervention/prespecification/blinding gaps. Distinguish absent subclaim score/status/axes from parent C with 50 points, Unknown safety and unrecorded precision. Do not convert large F/P or partial-effect statistics to direct score differences, CIs, importance thresholds or laughter-specific effects. Do not transfer other measures, cortisol, video, brief exposure or original samples to the same PSS effects/denominators. Create no new effects, CIs, totals, independence/safety certification or yoga/medical instructions.", "criterion": "Material for The scope of the selected grade and overall verdict must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.", "basis": "Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.", "condition_origin": "Internally applied conditions preserved for the existing subclaim. They do not establish preregistration, official-tool certification or completed content review.", "proposed_research": "Material needed: The selection has no separate score, status or assessment axes. No new grade or score is assigned. This records needed materials; no new research was executed." }, { "item_id": "N03", "question_type": "Evidence condition", "question": "Are psychiatric nurses psychiatric patients?", "needed": "Report-specific populations, diagnoses and selection criteria", "role": "Required", "role_reason": "This condition connects Report-specific populations, diagnoses and selection criteria with populations, programs, actual controls, measures, timing, denominators, models, prespecification, direct effects/CIs or harms for nonclinical perceived stress, distinguishing other mental-symptom measures, biomarkers and treatment claims.", "application_exception": "Preserve original subclaim C, positive signals and no-intervention/prespecification/blinding gaps. Distinguish absent subclaim score/status/axes from parent C with 50 points, Unknown safety and unrecorded precision. Do not convert large F/P or partial-effect statistics to direct score differences, CIs, importance thresholds or laughter-specific effects. Do not transfer other measures, cortisol, video, brief exposure or original samples to the same PSS effects/denominators. Create no new effects, CIs, totals, independence/safety certification or yoga/medical instructions.", "criterion": "Material for Report-specific populations, diagnoses and selection criteria must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.", "basis": "Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.", "condition_origin": "Internally applied conditions preserved for the existing subclaim. They do not establish preregistration, official-tool certification or completed content review.", "proposed_research": "Material needed: Report-specific diagnoses, exclusions, baseline stress, age, occupational distributions and applicability to other adults are unverified. This records needed materials; no new research was executed." }, { "item_id": "N04", "question_type": "Evidence condition", "question": "Is laughter itself the same as the group program?", "needed": "Program components and actual participation", "role": "Required", "role_reason": "This condition connects Program components and actual participation with populations, programs, actual controls, measures, timing, denominators, models, prespecification, direct effects/CIs or harms for nonclinical perceived stress, distinguishing other mental-symptom measures, biomarkers and treatment claims.", "application_exception": "Preserve original subclaim C, positive signals and no-intervention/prespecification/blinding gaps. Distinguish absent subclaim score/status/axes from parent C with 50 points, Unknown safety and unrecorded precision. Do not convert large F/P or partial-effect statistics to direct score differences, CIs, importance thresholds or laughter-specific effects. Do not transfer other measures, cortisol, video, brief exposure or original samples to the same PSS effects/denominators. Create no new effects, CIs, totals, independence/safety certification or yoga/medical instructions.", "criterion": "Material for Program components and actual participation must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.", "basis": "Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.", "condition_origin": "Internally applied conditions preserved for the existing subclaim. They do not establish preregistration, official-tool certification or completed content review.", "proposed_research": "Material needed: Report-specific components, instructors, contact, expectations, adherence and each component's contribution are unverified. This records needed materials; no new research was executed." }, { "item_id": "N05", "question_type": "Evidence condition", "question": "How do no intervention and active social controls differ?", "needed": "Arm-specific attention, contact, expectations and control content", "role": "Required", "role_reason": "This condition connects Arm-specific attention, contact, expectations and control content with populations, programs, actual controls, measures, timing, denominators, models, prespecification, direct effects/CIs or harms for nonclinical perceived stress, distinguishing other mental-symptom measures, biomarkers and treatment claims.", "application_exception": "Preserve original subclaim C, positive signals and no-intervention/prespecification/blinding gaps. Distinguish absent subclaim score/status/axes from parent C with 50 points, Unknown safety and unrecorded precision. Do not convert large F/P or partial-effect statistics to direct score differences, CIs, importance thresholds or laughter-specific effects. Do not transfer other measures, cortisol, video, brief exposure or original samples to the same PSS effects/denominators. Create no new effects, CIs, totals, independence/safety certification or yoga/medical instructions.", "criterion": "Material for Arm-specific attention, contact, expectations and control content must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.", "basis": "Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.", "condition_origin": "Internally applied conditions preserved for the existing subclaim. They do not establish preregistration, official-tool certification or completed content review.", "proposed_research": "Material needed: Arm-specific attention, contact and expectations, control specifications in other reports and direct comparisons of laughter-specific effects are unverified. This records needed materials; no new research was executed." }, { "item_id": "N06", "question_type": "Evidence condition", "question": "Do single and repeated programs show the same effect?", "needed": "Report-specific duration, frequency, exposure and follow-up", "role": "Required", "role_reason": "This condition connects Report-specific duration, frequency, exposure and follow-up with populations, programs, actual controls, measures, timing, denominators, models, prespecification, direct effects/CIs or harms for nonclinical perceived stress, distinguishing other mental-symptom measures, biomarkers and treatment claims.", "application_exception": "Preserve original subclaim C, positive signals and no-intervention/prespecification/blinding gaps. Distinguish absent subclaim score/status/axes from parent C with 50 points, Unknown safety and unrecorded precision. Do not convert large F/P or partial-effect statistics to direct score differences, CIs, importance thresholds or laughter-specific effects. Do not transfer other measures, cortisol, video, brief exposure or original samples to the same PSS effects/denominators. Create no new effects, CIs, totals, independence/safety certification or yoga/medical instructions.", "criterion": "Material for Report-specific duration, frequency, exposure and follow-up must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.", "basis": "Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.", "condition_origin": "Internally applied conditions preserved for the existing subclaim. They do not establish preregistration, official-tool certification or completed content review.", "proposed_research": "Material needed: Exact report-specific schedules, observation windows, actual exposure, adherence, valid denominators and persistence after completion are unverified. These are not practice recommendations. This records needed materials; no new research was executed." }, { "item_id": "N07", "question_type": "Evidence condition", "question": "What does the perceived-stress measure represent?", "needed": "Measure version, range, direction, timing and scores", "role": "Required", "role_reason": "This condition connects Measure version, range, direction, timing and scores with populations, programs, actual controls, measures, timing, denominators, models, prespecification, direct effects/CIs or harms for nonclinical perceived stress, distinguishing other mental-symptom measures, biomarkers and treatment claims.", "application_exception": "Preserve original subclaim C, positive signals and no-intervention/prespecification/blinding gaps. Distinguish absent subclaim score/status/axes from parent C with 50 points, Unknown safety and unrecorded precision. Do not convert large F/P or partial-effect statistics to direct score differences, CIs, importance thresholds or laughter-specific effects. Do not transfer other measures, cortisol, video, brief exposure or original samples to the same PSS effects/denominators. Create no new effects, CIs, totals, independence/safety certification or yoga/medical instructions.", "criterion": "Material for Measure version, range, direction, timing and scores must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.", "basis": "Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.", "condition_origin": "Internally applied conditions preserved for the existing subclaim. They do not establish preregistration, official-tool certification or completed content review.", "proposed_research": "Material needed: PSS version, range, direction, units, baseline and final scores, changes, aggregation, denominators and intervals are unverified. This records needed materials; no new research was executed." }, { "item_id": "N08", "question_type": "Evidence condition", "question": "Are other psychological measures also perceived stress?", "needed": "Definitions and outcome hierarchy for each measure", "role": "Required", "role_reason": "This condition connects Definitions and outcome hierarchy for each measure with populations, programs, actual controls, measures, timing, denominators, models, prespecification, direct effects/CIs or harms for nonclinical perceived stress, distinguishing other mental-symptom measures, biomarkers and treatment claims.", "application_exception": "Preserve original subclaim C, positive signals and no-intervention/prespecification/blinding gaps. Distinguish absent subclaim score/status/axes from parent C with 50 points, Unknown safety and unrecorded precision. Do not convert large F/P or partial-effect statistics to direct score differences, CIs, importance thresholds or laughter-specific effects. Do not transfer other measures, cortisol, video, brief exposure or original samples to the same PSS effects/denominators. Create no new effects, CIs, totals, independence/safety certification or yoga/medical instructions.", "criterion": "Material for Definitions and outcome hierarchy for each measure must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.", "basis": "Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.", "condition_origin": "Internally applied conditions preserved for the existing subclaim. They do not establish preregistration, official-tool certification or completed content review.", "proposed_research": "Material needed: Measure versions, primary/secondary hierarchy, direct effects, denominators, intervals and links to clinical diagnoses are unverified. This records needed materials; no new research was executed." }, { "item_id": "N09", "question_type": "Evidence condition", "question": "What does the PSS group-by-time statistic show?", "needed": "The original statistic versus direct score differences", "role": "Required", "role_reason": "This condition connects The original statistic versus direct score differences with populations, programs, actual controls, measures, timing, denominators, models, prespecification, direct effects/CIs or harms for nonclinical perceived stress, distinguishing other mental-symptom measures, biomarkers and treatment claims.", "application_exception": "Preserve original subclaim C, positive signals and no-intervention/prespecification/blinding gaps. Distinguish absent subclaim score/status/axes from parent C with 50 points, Unknown safety and unrecorded precision. Do not convert large F/P or partial-effect statistics to direct score differences, CIs, importance thresholds or laughter-specific effects. Do not transfer other measures, cortisol, video, brief exposure or original samples to the same PSS effects/denominators. Create no new effects, CIs, totals, independence/safety certification or yoga/medical instructions.", "criterion": "Material for The original statistic versus direct score differences must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.", "basis": "Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.", "condition_origin": "Internally applied conditions preserved for the existing subclaim. They do not establish preregistration, official-tool certification or completed content review.", "proposed_research": "Material needed: Arm-specific scores and changes, adjusted between-arm differences and confidence intervals, models, variances, baseline and time windows are unverified. This records needed materials; no new research was executed." }, { "item_id": "N10", "question_type": "Evidence condition", "question": "Does complete participation establish every outcome denominator?", "needed": "Measure- and time-specific analysis samples and units", "role": "Required", "role_reason": "This condition connects Measure- and time-specific analysis samples and units with populations, programs, actual controls, measures, timing, denominators, models, prespecification, direct effects/CIs or harms for nonclinical perceived stress, distinguishing other mental-symptom measures, biomarkers and treatment claims.", "application_exception": "Preserve original subclaim C, positive signals and no-intervention/prespecification/blinding gaps. Distinguish absent subclaim score/status/axes from parent C with 50 points, Unknown safety and unrecorded precision. Do not convert large F/P or partial-effect statistics to direct score differences, CIs, importance thresholds or laughter-specific effects. Do not transfer other measures, cortisol, video, brief exposure or original samples to the same PSS effects/denominators. Create no new effects, CIs, totals, independence/safety certification or yoga/medical instructions.", "criterion": "Material for Measure- and time-specific analysis samples and units must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.", "basis": "Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.", "condition_origin": "Internally applied conditions preserved for the existing subclaim. They do not establish preregistration, official-tool certification or completed content review.", "proposed_research": "Material needed: Measure- and time-specific valid denominators, missingness, group/individual analysis units and correspondence with harms data are unverified. This records needed materials; no new research was executed." }, { "item_id": "N11", "question_type": "Evidence condition", "question": "What limitation arises when the instructor is also the assessor?", "needed": "Role separation, blinding and data handling", "role": "Required", "role_reason": "This condition connects Role separation, blinding and data handling with populations, programs, actual controls, measures, timing, denominators, models, prespecification, direct effects/CIs or harms for nonclinical perceived stress, distinguishing other mental-symptom measures, biomarkers and treatment claims.", "application_exception": "Preserve original subclaim C, positive signals and no-intervention/prespecification/blinding gaps. Distinguish absent subclaim score/status/axes from parent C with 50 points, Unknown safety and unrecorded precision. Do not convert large F/P or partial-effect statistics to direct score differences, CIs, importance thresholds or laughter-specific effects. Do not transfer other measures, cortisol, video, brief exposure or original samples to the same PSS effects/denominators. Create no new effects, CIs, totals, independence/safety certification or yoga/medical instructions.", "criterion": "Material for Role separation, blinding and data handling must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.", "basis": "Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.", "condition_origin": "Internally applied conditions preserved for the existing subclaim. They do not establish preregistration, official-tool certification or completed content review.", "proposed_research": "Material needed: Assessment and recording blinding, role separation, expectation and attention controls, and data-handling procedures are unverified. This records needed materials; no new research was executed." }, { "item_id": "N12", "question_type": "Evidence condition", "question": "Were concerns about conduct and registration dates verified?", "needed": "Original schedules, registration, plans and amendments", "role": "Required", "role_reason": "This condition connects Original schedules, registration, plans and amendments with populations, programs, actual controls, measures, timing, denominators, models, prespecification, direct effects/CIs or harms for nonclinical perceived stress, distinguishing other mental-symptom measures, biomarkers and treatment claims.", "application_exception": "Preserve original subclaim C, positive signals and no-intervention/prespecification/blinding gaps. Distinguish absent subclaim score/status/axes from parent C with 50 points, Unknown safety and unrecorded precision. Do not convert large F/P or partial-effect statistics to direct score differences, CIs, importance thresholds or laughter-specific effects. Do not transfer other measures, cortisol, video, brief exposure or original samples to the same PSS effects/denominators. Create no new effects, CIs, totals, independence/safety certification or yoga/medical instructions.", "criterion": "Material for Original schedules, registration, plans and amendments must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.", "basis": "Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.", "condition_origin": "Internally applied conditions preserved for the existing subclaim. They do not establish preregistration, official-tool certification or completed content review.", "proposed_research": "Material needed: Exact conduct, registration and planning times, amendments, PSS hierarchy and consistency with original documents are unverified. This records needed materials; no new research was executed." }, { "item_id": "N13", "question_type": "Evidence condition", "question": "Are the abstract's null statement and multivariate statistic the same test?", "needed": "Measures, contrasts, models and original results for each statement", "role": "Required", "role_reason": "This condition connects Measures, contrasts, models and original results for each statement with populations, programs, actual controls, measures, timing, denominators, models, prespecification, direct effects/CIs or harms for nonclinical perceived stress, distinguishing other mental-symptom measures, biomarkers and treatment claims.", "application_exception": "Preserve original subclaim C, positive signals and no-intervention/prespecification/blinding gaps. Distinguish absent subclaim score/status/axes from parent C with 50 points, Unknown safety and unrecorded precision. Do not convert large F/P or partial-effect statistics to direct score differences, CIs, importance thresholds or laughter-specific effects. Do not transfer other measures, cortisol, video, brief exposure or original samples to the same PSS effects/denominators. Create no new effects, CIs, totals, independence/safety certification or yoga/medical instructions.", "criterion": "Material for Measures, contrasts, models and original results for each statement must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.", "basis": "Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.", "condition_origin": "Internally applied conditions preserved for the existing subclaim. They do not establish preregistration, official-tool certification or completed content review.", "proposed_research": "Material needed: The outcome, contrast and hierarchy of each test, individual PSS effects and confidence intervals, and multivariate models and denominators are unverified. This records needed materials; no new research was executed." }, { "item_id": "N14", "question_type": "Evidence condition", "question": "What do the analyzed sample and retrospective registration establish?", "needed": "Total allocation, exclusions, completion and registration timing", "role": "Required", "role_reason": "This condition connects Total allocation, exclusions, completion and registration timing with populations, programs, actual controls, measures, timing, denominators, models, prespecification, direct effects/CIs or harms for nonclinical perceived stress, distinguishing other mental-symptom measures, biomarkers and treatment claims.", "application_exception": "Preserve original subclaim C, positive signals and no-intervention/prespecification/blinding gaps. Distinguish absent subclaim score/status/axes from parent C with 50 points, Unknown safety and unrecorded precision. Do not convert large F/P or partial-effect statistics to direct score differences, CIs, importance thresholds or laughter-specific effects. Do not transfer other measures, cortisol, video, brief exposure or original samples to the same PSS effects/denominators. Create no new effects, CIs, totals, independence/safety certification or yoga/medical instructions.", "criterion": "Material for Total allocation, exclusions, completion and registration timing must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.", "basis": "Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.", "condition_origin": "Internally applied conditions preserved for the existing subclaim. They do not establish preregistration, official-tool certification or completed content review.", "proposed_research": "Material needed: Total allocation and exclusions, arm- and measure-specific valid denominators, registration and planning times and amendments are unverified. This records needed materials; no new research was executed." }, { "item_id": "N15", "question_type": "Evidence condition", "question": "Are mental-symptom results direct PSS results?", "needed": "Existence of perceived-stress measurement and individual results", "role": "Required", "role_reason": "This condition connects Existence of perceived-stress measurement and individual results with populations, programs, actual controls, measures, timing, denominators, models, prespecification, direct effects/CIs or harms for nonclinical perceived stress, distinguishing other mental-symptom measures, biomarkers and treatment claims.", "application_exception": "Preserve original subclaim C, positive signals and no-intervention/prespecification/blinding gaps. Distinguish absent subclaim score/status/axes from parent C with 50 points, Unknown safety and unrecorded precision. Do not convert large F/P or partial-effect statistics to direct score differences, CIs, importance thresholds or laughter-specific effects. Do not transfer other measures, cortisol, video, brief exposure or original samples to the same PSS effects/denominators. Create no new effects, CIs, totals, independence/safety certification or yoga/medical instructions.", "criterion": "Material for Existence of perceived-stress measurement and individual results must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.", "basis": "Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.", "condition_origin": "Internally applied conditions preserved for the existing subclaim. They do not establish preregistration, official-tool certification or completed content review.", "proposed_research": "Material needed: The mental-symptom instrument, existence of PSS measurement and individual effects, arm-, time- and session-specific denominators and plans are unverified. This records needed materials; no new research was executed." }, { "item_id": "N16", "question_type": "Evidence condition", "question": "Do acute biomarkers establish a perceived-stress effect?", "needed": "Direct perceived-stress outcomes versus biomarkers", "role": "Required", "role_reason": "This condition connects Direct perceived-stress outcomes versus biomarkers with populations, programs, actual controls, measures, timing, denominators, models, prespecification, direct effects/CIs or harms for nonclinical perceived stress, distinguishing other mental-symptom measures, biomarkers and treatment claims.", "application_exception": "Preserve original subclaim C, positive signals and no-intervention/prespecification/blinding gaps. Distinguish absent subclaim score/status/axes from parent C with 50 points, Unknown safety and unrecorded precision. Do not convert large F/P or partial-effect statistics to direct score differences, CIs, importance thresholds or laughter-specific effects. Do not transfer other measures, cortisol, video, brief exposure or original samples to the same PSS effects/denominators. Create no new effects, CIs, totals, independence/safety certification or yoga/medical instructions.", "criterion": "Material for Direct perceived-stress outcomes versus biomarkers must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.", "basis": "Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.", "condition_origin": "Internally applied conditions preserved for the existing subclaim. They do not establish preregistration, official-tool certification or completed content review.", "proposed_research": "Material needed: Existence of perceived-stress measurement and results, arm-specific denominators, exact cortisol contrasts and confidence intervals, and single-exposure and time-of-day plans are unverified. This records needed materials; no new research was executed." }, { "item_id": "N17", "question_type": "Evidence condition", "question": "Are changes with humorous video attributed to laughter yoga?", "needed": "Direct comparisons of different interventions", "role": "Required", "role_reason": "This condition connects Direct comparisons of different interventions with populations, programs, actual controls, measures, timing, denominators, models, prespecification, direct effects/CIs or harms for nonclinical perceived stress, distinguishing other mental-symptom measures, biomarkers and treatment claims.", "application_exception": "Preserve original subclaim C, positive signals and no-intervention/prespecification/blinding gaps. Distinguish absent subclaim score/status/axes from parent C with 50 points, Unknown safety and unrecorded precision. Do not convert large F/P or partial-effect statistics to direct score differences, CIs, importance thresholds or laughter-specific effects. Do not transfer other measures, cortisol, video, brief exposure or original samples to the same PSS effects/denominators. Create no new effects, CIs, totals, independence/safety certification or yoga/medical instructions.", "criterion": "Material for Direct comparisons of different interventions must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.", "basis": "Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.", "condition_origin": "Internally applied conditions preserved for the existing subclaim. They do not establish preregistration, official-tool certification or completed content review.", "proposed_research": "Material needed: Contributions of laughter, video, breathing, attention and social participation, and direct PSS contrasts are unverified. This records needed materials; no new research was executed." }, { "item_id": "N18", "question_type": "Evidence condition", "question": "Does cortisol substitute for perceived stress or treatment?", "needed": "Links between biomarkers, self-report and treatment of diagnosed conditions", "role": "Required", "role_reason": "This condition connects Links between biomarkers, self-report and treatment of diagnosed conditions with populations, programs, actual controls, measures, timing, denominators, models, prespecification, direct effects/CIs or harms for nonclinical perceived stress, distinguishing other mental-symptom measures, biomarkers and treatment claims.", "application_exception": "Preserve original subclaim C, positive signals and no-intervention/prespecification/blinding gaps. Distinguish absent subclaim score/status/axes from parent C with 50 points, Unknown safety and unrecorded precision. Do not convert large F/P or partial-effect statistics to direct score differences, CIs, importance thresholds or laughter-specific effects. Do not transfer other measures, cortisol, video, brief exposure or original samples to the same PSS effects/denominators. Create no new effects, CIs, totals, independence/safety certification or yoga/medical instructions.", "criterion": "Material for Links between biomarkers, self-report and treatment of diagnosed conditions must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.", "basis": "Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.", "condition_origin": "Internally applied conditions preserved for the existing subclaim. They do not establish preregistration, official-tool certification or completed content review.", "proposed_research": "Material needed: Links between biomarkers, self-report and treatment of diagnosed conditions, exact intervals and correspondence with the selected outcome are unverified. This records needed materials; no new research was executed." }, { "item_id": "N19", "question_type": "Evidence condition", "question": "Do nonclinical results establish treatment of depression or anxiety disorders?", "needed": "Direct evidence in diagnosed patients and treatment outcomes", "role": "Required", "role_reason": "This condition connects Direct evidence in diagnosed patients and treatment outcomes with populations, programs, actual controls, measures, timing, denominators, models, prespecification, direct effects/CIs or harms for nonclinical perceived stress, distinguishing other mental-symptom measures, biomarkers and treatment claims.", "application_exception": "Preserve original subclaim C, positive signals and no-intervention/prespecification/blinding gaps. Distinguish absent subclaim score/status/axes from parent C with 50 points, Unknown safety and unrecorded precision. Do not convert large F/P or partial-effect statistics to direct score differences, CIs, importance thresholds or laughter-specific effects. Do not transfer other measures, cortisol, video, brief exposure or original samples to the same PSS effects/denominators. Create no new effects, CIs, totals, independence/safety certification or yoga/medical instructions.", "criterion": "Material for Direct evidence in diagnosed patients and treatment outcomes must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.", "basis": "Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.", "condition_origin": "Internally applied conditions preserved for the existing subclaim. They do not establish preregistration, official-tool certification or completed content review.", "proposed_research": "Material needed: Treatment, recovery and clinical events in diagnosed patients and their effects and intervals are outside this scope and unverified. This records needed materials; no new research was executed." }, { "item_id": "N20", "question_type": "Evidence condition", "question": "Does a randomized-design label verify the procedure?", "needed": "Sequence generation, concealment, allocation units and selection procedures", "role": "Required", "role_reason": "This condition connects Sequence generation, concealment, allocation units and selection procedures with populations, programs, actual controls, measures, timing, denominators, models, prespecification, direct effects/CIs or harms for nonclinical perceived stress, distinguishing other mental-symptom measures, biomarkers and treatment claims.", "application_exception": "Preserve original subclaim C, positive signals and no-intervention/prespecification/blinding gaps. Distinguish absent subclaim score/status/axes from parent C with 50 points, Unknown safety and unrecorded precision. Do not convert large F/P or partial-effect statistics to direct score differences, CIs, importance thresholds or laughter-specific effects. Do not transfer other measures, cortisol, video, brief exposure or original samples to the same PSS effects/denominators. Create no new effects, CIs, totals, independence/safety certification or yoga/medical instructions.", "criterion": "Material for Sequence generation, concealment, allocation units and selection procedures must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.", "basis": "Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.", "condition_origin": "Internally applied conditions preserved for the existing subclaim. They do not establish preregistration, official-tool certification or completed content review.", "proposed_research": "Material needed: Sequence generation, allocation concealment and units, group and individual baseline balance, and selection and exclusion procedures are unverified. This records needed materials; no new research was executed." }, { "item_id": "N21", "question_type": "Evidence condition", "question": "How were self-report and assessor blinding handled?", "needed": "Recording, aggregation, analysis and expectation controls", "role": "Required", "role_reason": "This condition connects Recording, aggregation, analysis and expectation controls with populations, programs, actual controls, measures, timing, denominators, models, prespecification, direct effects/CIs or harms for nonclinical perceived stress, distinguishing other mental-symptom measures, biomarkers and treatment claims.", "application_exception": "Preserve original subclaim C, positive signals and no-intervention/prespecification/blinding gaps. Distinguish absent subclaim score/status/axes from parent C with 50 points, Unknown safety and unrecorded precision. Do not convert large F/P or partial-effect statistics to direct score differences, CIs, importance thresholds or laughter-specific effects. Do not transfer other measures, cortisol, video, brief exposure or original samples to the same PSS effects/denominators. Create no new effects, CIs, totals, independence/safety certification or yoga/medical instructions.", "criterion": "Material for Recording, aggregation, analysis and expectation controls must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.", "basis": "Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.", "condition_origin": "Internally applied conditions preserved for the existing subclaim. They do not establish preregistration, official-tool certification or completed content review.", "proposed_research": "Material needed: Assessment, aggregation and analysis blinding, PSS recording instruction and missingness, expectation controls and consistent procedures are unverified. This records needed materials; no new research was executed." }, { "item_id": "N22", "question_type": "Evidence condition", "question": "Were primary outcomes and multiple-analysis plans verified?", "needed": "Prespecified measures, models, times and multiplicity", "role": "Required", "role_reason": "This condition connects Prespecified measures, models, times and multiplicity with populations, programs, actual controls, measures, timing, denominators, models, prespecification, direct effects/CIs or harms for nonclinical perceived stress, distinguishing other mental-symptom measures, biomarkers and treatment claims.", "application_exception": "Preserve original subclaim C, positive signals and no-intervention/prespecification/blinding gaps. Distinguish absent subclaim score/status/axes from parent C with 50 points, Unknown safety and unrecorded precision. Do not convert large F/P or partial-effect statistics to direct score differences, CIs, importance thresholds or laughter-specific effects. Do not transfer other measures, cortisol, video, brief exposure or original samples to the same PSS effects/denominators. Create no new effects, CIs, totals, independence/safety certification or yoga/medical instructions.", "criterion": "Material for Prespecified measures, models, times and multiplicity must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.", "basis": "Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.", "condition_origin": "Internally applied conditions preserved for the existing subclaim. They do not establish preregistration, official-tool certification or completed content review.", "proposed_research": "Material needed: Primary/secondary hierarchy for PSS, GHQ, burnout, well-being and biomarkers, models, timing, multiplicity and planning times are unverified. This records needed materials; no new research was executed." }, { "item_id": "N23", "question_type": "Evidence condition", "question": "What were baseline stress and other activities?", "needed": "Arm-specific baseline status and concurrent activities or treatment", "role": "Required", "role_reason": "This condition connects Arm-specific baseline status and concurrent activities or treatment with populations, programs, actual controls, measures, timing, denominators, models, prespecification, direct effects/CIs or harms for nonclinical perceived stress, distinguishing other mental-symptom measures, biomarkers and treatment claims.", "application_exception": "Preserve original subclaim C, positive signals and no-intervention/prespecification/blinding gaps. Distinguish absent subclaim score/status/axes from parent C with 50 points, Unknown safety and unrecorded precision. Do not convert large F/P or partial-effect statistics to direct score differences, CIs, importance thresholds or laughter-specific effects. Do not transfer other measures, cortisol, video, brief exposure or original samples to the same PSS effects/denominators. Create no new effects, CIs, totals, independence/safety certification or yoga/medical instructions.", "criterion": "Material for Arm-specific baseline status and concurrent activities or treatment must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.", "basis": "Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.", "condition_origin": "Internally applied conditions preserved for the existing subclaim. They do not establish preregistration, official-tool certification or completed content review.", "proposed_research": "Material needed: Baseline measures and status, arm-specific counseling, activities and treatment, confounding, adjustment and exposure changes are unverified. This records needed materials; no new research was executed." }, { "item_id": "N24", "question_type": "Evidence condition", "question": "Are group-by-time, between-arm and multivariate results the same estimate?", "needed": "Analysis populations, units, contrasts and models", "role": "Required", "role_reason": "This condition connects Analysis populations, units, contrasts and models with populations, programs, actual controls, measures, timing, denominators, models, prespecification, direct effects/CIs or harms for nonclinical perceived stress, distinguishing other mental-symptom measures, biomarkers and treatment claims.", "application_exception": "Preserve original subclaim C, positive signals and no-intervention/prespecification/blinding gaps. Distinguish absent subclaim score/status/axes from parent C with 50 points, Unknown safety and unrecorded precision. Do not convert large F/P or partial-effect statistics to direct score differences, CIs, importance thresholds or laughter-specific effects. Do not transfer other measures, cortisol, video, brief exposure or original samples to the same PSS effects/denominators. Create no new effects, CIs, totals, independence/safety certification or yoga/medical instructions.", "criterion": "Material for Analysis populations, units, contrasts and models must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.", "basis": "Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.", "condition_origin": "Internally applied conditions preserved for the existing subclaim. They do not establish preregistration, official-tool certification or completed content review.", "proposed_research": "Material needed: Analysis populations and units, covariates, measures and contrasts, baseline adjustment, arm-specific tables and intervals are unverified. This records needed materials; no new research was executed." }, { "item_id": "N25", "question_type": "Evidence condition", "question": "Do completion and analysis counts establish valid data for every measure?", "needed": "Arm-, measure-, visit- and session-specific missingness and exclusions", "role": "Required", "role_reason": "This condition connects Arm-, measure-, visit- and session-specific missingness and exclusions with populations, programs, actual controls, measures, timing, denominators, models, prespecification, direct effects/CIs or harms for nonclinical perceived stress, distinguishing other mental-symptom measures, biomarkers and treatment claims.", "application_exception": "Preserve original subclaim C, positive signals and no-intervention/prespecification/blinding gaps. Distinguish absent subclaim score/status/axes from parent C with 50 points, Unknown safety and unrecorded precision. Do not convert large F/P or partial-effect statistics to direct score differences, CIs, importance thresholds or laughter-specific effects. Do not transfer other measures, cortisol, video, brief exposure or original samples to the same PSS effects/denominators. Create no new effects, CIs, totals, independence/safety certification or yoga/medical instructions.", "criterion": "Material for Arm-, measure-, visit- and session-specific missingness and exclusions must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.", "basis": "Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.", "condition_origin": "Internally applied conditions preserved for the existing subclaim. They do not establish preregistration, official-tool certification or completed content review.", "proposed_research": "Material needed: Arm-, measure-, visit- and session-specific missingness, follow-up loss, exclusions, imputation and sensitivity analyses are unverified. This records needed materials; no new research was executed." }, { "item_id": "N26", "question_type": "Evidence condition", "question": "Does a large statistic establish exact effects and clinical importance?", "needed": "Direct score differences, intervals and importance thresholds", "role": "Required", "role_reason": "This condition connects Direct score differences, intervals and importance thresholds with populations, programs, actual controls, measures, timing, denominators, models, prespecification, direct effects/CIs or harms for nonclinical perceived stress, distinguishing other mental-symptom measures, biomarkers and treatment claims.", "application_exception": "Preserve original subclaim C, positive signals and no-intervention/prespecification/blinding gaps. Distinguish absent subclaim score/status/axes from parent C with 50 points, Unknown safety and unrecorded precision. Do not convert large F/P or partial-effect statistics to direct score differences, CIs, importance thresholds or laughter-specific effects. Do not transfer other measures, cortisol, video, brief exposure or original samples to the same PSS effects/denominators. Create no new effects, CIs, totals, independence/safety certification or yoga/medical instructions.", "criterion": "Material for Direct score differences, intervals and importance thresholds must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.", "basis": "Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.", "condition_origin": "Internally applied conditions preserved for the existing subclaim. They do not establish preregistration, official-tool certification or completed content review.", "proposed_research": "Material needed: Exact direct score differences, confidence intervals, importance thresholds, variances, denominators and individual applicability are unverified. This records needed materials; no new research was executed." }, { "item_id": "N27", "question_type": "Evidence condition", "question": "Are null, conflicting and mixed results retained?", "needed": "Complete results and selective reporting", "role": "Required", "role_reason": "This condition connects Complete results and selective reporting with populations, programs, actual controls, measures, timing, denominators, models, prespecification, direct effects/CIs or harms for nonclinical perceived stress, distinguishing other mental-symptom measures, biomarkers and treatment claims.", "application_exception": "Preserve original subclaim C, positive signals and no-intervention/prespecification/blinding gaps. Distinguish absent subclaim score/status/axes from parent C with 50 points, Unknown safety and unrecorded precision. Do not convert large F/P or partial-effect statistics to direct score differences, CIs, importance thresholds or laughter-specific effects. Do not transfer other measures, cortisol, video, brief exposure or original samples to the same PSS effects/denominators. Create no new effects, CIs, totals, independence/safety certification or yoga/medical instructions.", "criterion": "Material for Complete results and selective reporting must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.", "basis": "Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.", "condition_origin": "Internally applied conditions preserved for the existing subclaim. They do not establish preregistration, official-tool certification or completed content review.", "proposed_research": "Material needed: Complete external texts, tests and models, selected outcomes and contrasts, and the extent of omissions and selective reporting are unverified. This records needed materials; no new research was executed." }, { "item_id": "N28", "question_type": "Evidence condition", "question": "Are different samples, durations and controls pooled?", "needed": "Condition-specific direct results and prespecified subgroups", "role": "Required", "role_reason": "This condition connects Condition-specific direct results and prespecified subgroups with populations, programs, actual controls, measures, timing, denominators, models, prespecification, direct effects/CIs or harms for nonclinical perceived stress, distinguishing other mental-symptom measures, biomarkers and treatment claims.", "application_exception": "Preserve original subclaim C, positive signals and no-intervention/prespecification/blinding gaps. Distinguish absent subclaim score/status/axes from parent C with 50 points, Unknown safety and unrecorded precision. Do not convert large F/P or partial-effect statistics to direct score differences, CIs, importance thresholds or laughter-specific effects. Do not transfer other measures, cortisol, video, brief exposure or original samples to the same PSS effects/denominators. Create no new effects, CIs, totals, independence/safety certification or yoga/medical instructions.", "criterion": "Material for Condition-specific direct results and prespecified subgroups must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.", "basis": "Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.", "condition_origin": "Internally applied conditions preserved for the existing subclaim. They do not establish preregistration, official-tool certification or completed content review.", "proposed_research": "Material needed: Prespecified subgroups for the selected measure, direct differences, condition-specific intervals and models and all included data are unverified. This records needed materials; no new research was executed." }, { "item_id": "N29", "question_type": "Evidence condition", "question": "Do short programs answer long-term questions for all adults?", "needed": "Persistence after completion and direct population-specific data", "role": "Required", "role_reason": "This condition connects Persistence after completion and direct population-specific data with populations, programs, actual controls, measures, timing, denominators, models, prespecification, direct effects/CIs or harms for nonclinical perceived stress, distinguishing other mental-symptom measures, biomarkers and treatment claims.", "application_exception": "Preserve original subclaim C, positive signals and no-intervention/prespecification/blinding gaps. Distinguish absent subclaim score/status/axes from parent C with 50 points, Unknown safety and unrecorded precision. Do not convert large F/P or partial-effect statistics to direct score differences, CIs, importance thresholds or laughter-specific effects. Do not transfer other measures, cortisol, video, brief exposure or original samples to the same PSS effects/denominators. Create no new effects, CIs, totals, independence/safety certification or yoga/medical instructions.", "criterion": "Material for Persistence after completion and direct population-specific data must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.", "basis": "Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.", "condition_origin": "Internally applied conditions preserved for the existing subclaim. They do not establish preregistration, official-tool certification or completed content review.", "proposed_research": "Material needed: Persistence after completion, long-term and specific populations, prespecified program- and baseline-specific differences and direct intervals are unverified. This records needed materials; no new research was executed." }, { "item_id": "N30", "question_type": "Evidence condition", "question": "Is the report count a total of independent trials or participants?", "needed": "Related reports, registration, recruitment and overlap", "role": "Required", "role_reason": "This condition connects Related reports, registration, recruitment and overlap with populations, programs, actual controls, measures, timing, denominators, models, prespecification, direct effects/CIs or harms for nonclinical perceived stress, distinguishing other mental-symptom measures, biomarkers and treatment claims.", "application_exception": "Preserve original subclaim C, positive signals and no-intervention/prespecification/blinding gaps. Distinguish absent subclaim score/status/axes from parent C with 50 points, Unknown safety and unrecorded precision. Do not convert large F/P or partial-effect statistics to direct score differences, CIs, importance thresholds or laughter-specific effects. Do not transfer other measures, cortisol, video, brief exposure or original samples to the same PSS effects/denominators. Create no new effects, CIs, totals, independence/safety certification or yoga/medical instructions.", "criterion": "Material for Related reports, registration, recruitment and overlap must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.", "basis": "Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.", "condition_origin": "Internally applied conditions preserved for the existing subclaim. They do not establish preregistration, official-tool certification or completed content review.", "proposed_research": "Material needed: Correspondence between registration, recruitment, groups and related reports, and unique trial, participant and event counts are unverified. This records needed materials; no new research was executed." }, { "item_id": "N31", "question_type": "Evidence condition", "question": "Does a registration identifier mean its content was checked now?", "needed": "Registration originals, amendments, plans and report correspondence", "role": "Required", "role_reason": "This condition connects Registration originals, amendments, plans and report correspondence with populations, programs, actual controls, measures, timing, denominators, models, prespecification, direct effects/CIs or harms for nonclinical perceived stress, distinguishing other mental-symptom measures, biomarkers and treatment claims.", "application_exception": "Preserve original subclaim C, positive signals and no-intervention/prespecification/blinding gaps. Distinguish absent subclaim score/status/axes from parent C with 50 points, Unknown safety and unrecorded precision. Do not convert large F/P or partial-effect statistics to direct score differences, CIs, importance thresholds or laughter-specific effects. Do not transfer other measures, cortisol, video, brief exposure or original samples to the same PSS effects/denominators. Create no new effects, CIs, totals, independence/safety certification or yoga/medical instructions.", "criterion": "Material for Registration originals, amendments, plans and report correspondence must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.", "basis": "Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.", "condition_origin": "Internally applied conditions preserved for the existing subclaim. They do not establish preregistration, official-tool certification or completed content review.", "proposed_research": "Material needed: Registration, amendment and planning times and correspondence with recruitment, endpoints and reports were not verified in this work. This records needed materials; no new research was executed." }, { "item_id": "N32", "question_type": "Evidence condition", "question": "Are funding/conflict declarations the same as combined roles?", "needed": "Support, contracts, involvement and role separation", "role": "Required", "role_reason": "This condition connects Support, contracts, involvement and role separation with populations, programs, actual controls, measures, timing, denominators, models, prespecification, direct effects/CIs or harms for nonclinical perceived stress, distinguishing other mental-symptom measures, biomarkers and treatment claims.", "application_exception": "Preserve original subclaim C, positive signals and no-intervention/prespecification/blinding gaps. Distinguish absent subclaim score/status/axes from parent C with 50 points, Unknown safety and unrecorded precision. Do not convert large F/P or partial-effect statistics to direct score differences, CIs, importance thresholds or laughter-specific effects. Do not transfer other measures, cortisol, video, brief exposure or original samples to the same PSS effects/denominators. Create no new effects, CIs, totals, independence/safety certification or yoga/medical instructions.", "criterion": "Material for Support, contracts, involvement and role separation must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.", "basis": "Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.", "condition_origin": "Internally applied conditions preserved for the existing subclaim. They do not establish preregistration, official-tool certification or completed content review.", "proposed_research": "Material needed: Support, contracts, training, analysis and publication involvement, current conflict disclosures and independent confirmation are unverified. This records needed materials; no new research was executed." }, { "item_id": "N33", "question_type": "Evidence condition", "question": "What material was actually read here?", "needed": "Stored summaries versus external originals", "role": "Required", "role_reason": "This condition connects Stored summaries versus external originals with populations, programs, actual controls, measures, timing, denominators, models, prespecification, direct effects/CIs or harms for nonclinical perceived stress, distinguishing other mental-symptom measures, biomarkers and treatment claims.", "application_exception": "Preserve original subclaim C, positive signals and no-intervention/prespecification/blinding gaps. Distinguish absent subclaim score/status/axes from parent C with 50 points, Unknown safety and unrecorded precision. Do not convert large F/P or partial-effect statistics to direct score differences, CIs, importance thresholds or laughter-specific effects. Do not transfer other measures, cortisol, video, brief exposure or original samples to the same PSS effects/denominators. Create no new effects, CIs, totals, independence/safety certification or yoga/medical instructions.", "criterion": "Material for Stored summaries versus external originals must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.", "basis": "Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.", "condition_origin": "Internally applied conditions preserved for the existing subclaim. They do not establish preregistration, official-tool certification or completed content review.", "proposed_research": "Material needed: External identity, content, availability and acquisition, measure-specific tables, models, plans and registration are unverified. This records needed materials; no new research was executed." }, { "item_id": "N34", "question_type": "Evidence condition", "question": "What do the evidence date and bibliographic years mean?", "needed": "The original evidence reference date and historical reading records", "role": "Required", "role_reason": "This condition connects The original evidence reference date and historical reading records with populations, programs, actual controls, measures, timing, denominators, models, prespecification, direct effects/CIs or harms for nonclinical perceived stress, distinguishing other mental-symptom measures, biomarkers and treatment claims.", "application_exception": "Preserve original subclaim C, positive signals and no-intervention/prespecification/blinding gaps. Distinguish absent subclaim score/status/axes from parent C with 50 points, Unknown safety and unrecorded precision. Do not convert large F/P or partial-effect statistics to direct score differences, CIs, importance thresholds or laughter-specific effects. Do not transfer other measures, cortisol, video, brief exposure or original samples to the same PSS effects/denominators. Create no new effects, CIs, totals, independence/safety certification or yoga/medical instructions.", "criterion": "Material for The original evidence reference date and historical reading records must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.", "basis": "Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.", "condition_origin": "Internally applied conditions preserved for the existing subclaim. They do not establish preregistration, official-tool certification or completed content review.", "proposed_research": "Material needed: The original search end date, historical access locations and times, and current external materials and correction details are unverified. The reference date is not a new external reading date. This records needed materials; no new research was executed." }, { "item_id": "N35", "question_type": "Evidence condition", "question": "How are the selected question and parent explanation retained?", "needed": "Korean/English selected wording and outcome scope", "role": "Required", "role_reason": "This condition connects Korean/English selected wording and outcome scope with populations, programs, actual controls, measures, timing, denominators, models, prespecification, direct effects/CIs or harms for nonclinical perceived stress, distinguishing other mental-symptom measures, biomarkers and treatment claims.", "application_exception": "Preserve original subclaim C, positive signals and no-intervention/prespecification/blinding gaps. Distinguish absent subclaim score/status/axes from parent C with 50 points, Unknown safety and unrecorded precision. Do not convert large F/P or partial-effect statistics to direct score differences, CIs, importance thresholds or laughter-specific effects. Do not transfer other measures, cortisol, video, brief exposure or original samples to the same PSS effects/denominators. Create no new effects, CIs, totals, independence/safety certification or yoga/medical instructions.", "criterion": "Material for Korean/English selected wording and outcome scope must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.", "basis": "Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.", "condition_origin": "Internally applied conditions preserved for the existing subclaim. They do not establish preregistration, official-tool certification or completed content review.", "proposed_research": "Material needed: Detailed external translation and correction comparisons and individual content review remain incomplete. No new selected score or status is created. This records needed materials; no new research was executed." }, { "item_id": "N36", "question_type": "Evidence condition", "question": "Do parent assessment axes provide new certification for the selection?", "needed": "Parent records versus selected assessment", "role": "Required", "role_reason": "This condition connects Parent records versus selected assessment with populations, programs, actual controls, measures, timing, denominators, models, prespecification, direct effects/CIs or harms for nonclinical perceived stress, distinguishing other mental-symptom measures, biomarkers and treatment claims.", "application_exception": "Preserve original subclaim C, positive signals and no-intervention/prespecification/blinding gaps. Distinguish absent subclaim score/status/axes from parent C with 50 points, Unknown safety and unrecorded precision. Do not convert large F/P or partial-effect statistics to direct score differences, CIs, importance thresholds or laughter-specific effects. Do not transfer other measures, cortisol, video, brief exposure or original samples to the same PSS effects/denominators. Create no new effects, CIs, totals, independence/safety certification or yoga/medical instructions.", "criterion": "Material for Parent records versus selected assessment must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.", "basis": "Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.", "condition_origin": "Internally applied conditions preserved for the existing subclaim. They do not establish preregistration, official-tool certification or completed content review.", "proposed_research": "Material needed: No new formal selected assessment or precision, independence, prespecification or quality certification was performed. This records needed materials; no new research was executed." }, { "item_id": "N37", "question_type": "Evidence condition", "question": "Are boundaries involving dizziness and hyperventilation actual event tables?", "needed": "Harms definitions, collection and direct arm-specific data", "role": "Required", "role_reason": "This condition connects Harms definitions, collection and direct arm-specific data with populations, programs, actual controls, measures, timing, denominators, models, prespecification, direct effects/CIs or harms for nonclinical perceived stress, distinguishing other mental-symptom measures, biomarkers and treatment claims.", "application_exception": "Preserve original subclaim C, positive signals and no-intervention/prespecification/blinding gaps. Distinguish absent subclaim score/status/axes from parent C with 50 points, Unknown safety and unrecorded precision. Do not convert large F/P or partial-effect statistics to direct score differences, CIs, importance thresholds or laughter-specific effects. Do not transfer other measures, cortisol, video, brief exposure or original samples to the same PSS effects/denominators. Create no new effects, CIs, totals, independence/safety certification or yoga/medical instructions.", "criterion": "Material for Harms definitions, collection and direct arm-specific data must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.", "basis": "Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.", "condition_origin": "Internally applied conditions preserved for the existing subclaim. They do not establish preregistration, official-tool certification or completed content review.", "proposed_research": "Material needed: Arm-specific people and event counts, definitions, diagnoses, severity, active or spontaneous collection and missingness are unverified. This records needed materials; no new research was executed." }, { "item_id": "N38", "question_type": "Evidence condition", "question": "Are exposure, event, discontinuation and recovery times known?", "needed": "Arm-specific events, actual exposure and timing", "role": "Required", "role_reason": "This condition connects Arm-specific events, actual exposure and timing with populations, programs, actual controls, measures, timing, denominators, models, prespecification, direct effects/CIs or harms for nonclinical perceived stress, distinguishing other mental-symptom measures, biomarkers and treatment claims.", "application_exception": "Preserve original subclaim C, positive signals and no-intervention/prespecification/blinding gaps. Distinguish absent subclaim score/status/axes from parent C with 50 points, Unknown safety and unrecorded precision. Do not convert large F/P or partial-effect statistics to direct score differences, CIs, importance thresholds or laughter-specific effects. Do not transfer other measures, cortisol, video, brief exposure or original samples to the same PSS effects/denominators. Create no new effects, CIs, totals, independence/safety certification or yoga/medical instructions.", "criterion": "Material for Arm-specific events, actual exposure and timing must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.", "basis": "Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.", "condition_origin": "Internally applied conditions preserved for the existing subclaim. They do not establish preregistration, official-tool certification or completed content review.", "proposed_research": "Material needed: Arm-specific events and actual exposure, onset, recovery, discontinuation, re-exposure and follow-up times are unverified. This records needed materials; no new research was executed." }, { "item_id": "N39", "question_type": "Evidence condition", "question": "Can harms rates and comparative risks be determined?", "needed": "Arm-specific events, people, time and valid denominators", "role": "Required", "role_reason": "This condition connects Arm-specific events, people, time and valid denominators with populations, programs, actual controls, measures, timing, denominators, models, prespecification, direct effects/CIs or harms for nonclinical perceived stress, distinguishing other mental-symptom measures, biomarkers and treatment claims.", "application_exception": "Preserve original subclaim C, positive signals and no-intervention/prespecification/blinding gaps. Distinguish absent subclaim score/status/axes from parent C with 50 points, Unknown safety and unrecorded precision. Do not convert large F/P or partial-effect statistics to direct score differences, CIs, importance thresholds or laughter-specific effects. Do not transfer other measures, cortisol, video, brief exposure or original samples to the same PSS effects/denominators. Create no new effects, CIs, totals, independence/safety certification or yoga/medical instructions.", "criterion": "Material for Arm-specific events, people, time and valid denominators must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.", "basis": "Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.", "condition_origin": "Internally applied conditions preserved for the existing subclaim. They do not establish preregistration, official-tool certification or completed content review.", "proposed_research": "Material needed: Arm-specific harms, people, event counts and duplicates, exposure, time, denominators, comparisons and confidence intervals are unverified. This records needed materials; no new research was executed." }, { "item_id": "N40", "question_type": "Evidence condition", "question": "What about baseline conditions, concurrent activities and special populations?", "needed": "Population- and activity-specific harms and alternative causes", "role": "Required", "role_reason": "This condition connects Population- and activity-specific harms and alternative causes with populations, programs, actual controls, measures, timing, denominators, models, prespecification, direct effects/CIs or harms for nonclinical perceived stress, distinguishing other mental-symptom measures, biomarkers and treatment claims.", "application_exception": "Preserve original subclaim C, positive signals and no-intervention/prespecification/blinding gaps. Distinguish absent subclaim score/status/axes from parent C with 50 points, Unknown safety and unrecorded precision. Do not convert large F/P or partial-effect statistics to direct score differences, CIs, importance thresholds or laughter-specific effects. Do not transfer other measures, cortisol, video, brief exposure or original samples to the same PSS effects/denominators. Create no new effects, CIs, totals, independence/safety certification or yoga/medical instructions.", "criterion": "Material for Population- and activity-specific harms and alternative causes must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.", "basis": "Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.", "condition_origin": "Internally applied conditions preserved for the existing subclaim. They do not establish preregistration, official-tool certification or completed content review.", "proposed_research": "Material needed: Direct population- and activity-specific events, alternative causes, long-term, rare and vulnerable-population information and risk magnitude are unverified. This records needed materials; no new research was executed." }, { "item_id": "N41", "question_type": "Evidence condition", "question": "Are shared reports summed as independent events?", "needed": "Overlap between reports, missingness, people and events", "role": "Required", "role_reason": "This condition connects Overlap between reports, missingness, people and events with populations, programs, actual controls, measures, timing, denominators, models, prespecification, direct effects/CIs or harms for nonclinical perceived stress, distinguishing other mental-symptom measures, biomarkers and treatment claims.", "application_exception": "Preserve original subclaim C, positive signals and no-intervention/prespecification/blinding gaps. Distinguish absent subclaim score/status/axes from parent C with 50 points, Unknown safety and unrecorded precision. Do not convert large F/P or partial-effect statistics to direct score differences, CIs, importance thresholds or laughter-specific effects. Do not transfer other measures, cortisol, video, brief exposure or original samples to the same PSS effects/denominators. Create no new effects, CIs, totals, independence/safety certification or yoga/medical instructions.", "criterion": "Material for Overlap between reports, missingness, people and events must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.", "basis": "Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.", "condition_origin": "Internally applied conditions preserved for the existing subclaim. They do not establish preregistration, official-tool certification or completed content review.", "proposed_research": "Material needed: Reporting, detection, selection, arm-specific losses, unique people, events and study families and the extent of all public data are unverified. This records needed materials; no new research was executed." }, { "item_id": "N42", "question_type": "Evidence condition", "question": "What do the signals and gaps establish?", "needed": "Direct PSS results and interpretation boundaries", "role": "Required", "role_reason": "This condition connects Direct PSS results and interpretation boundaries with populations, programs, actual controls, measures, timing, denominators, models, prespecification, direct effects/CIs or harms for nonclinical perceived stress, distinguishing other mental-symptom measures, biomarkers and treatment claims.", "application_exception": "Preserve original subclaim C, positive signals and no-intervention/prespecification/blinding gaps. Distinguish absent subclaim score/status/axes from parent C with 50 points, Unknown safety and unrecorded precision. Do not convert large F/P or partial-effect statistics to direct score differences, CIs, importance thresholds or laughter-specific effects. Do not transfer other measures, cortisol, video, brief exposure or original samples to the same PSS effects/denominators. Create no new effects, CIs, totals, independence/safety certification or yoga/medical instructions.", "criterion": "Material for Direct PSS results and interpretation boundaries must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.", "basis": "Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.", "condition_origin": "Internally applied conditions preserved for the existing subclaim. They do not establish preregistration, official-tool certification or completed content review.", "proposed_research": "Material needed: Direct PSS effects and confidence intervals, active social controls, prespecification, models, denominators, long-term outcomes and harms data remain needed. This records needed materials; no new research was executed." }, { "item_id": "N43", "question_type": "Evidence condition", "question": "Does linking methods documents complete content review?", "needed": "Production methodology materials and review status", "role": "Required", "role_reason": "This condition connects Production methodology materials and review status with populations, programs, actual controls, measures, timing, denominators, models, prespecification, direct effects/CIs or harms for nonclinical perceived stress, distinguishing other mental-symptom measures, biomarkers and treatment claims.", "application_exception": "Preserve original subclaim C, positive signals and no-intervention/prespecification/blinding gaps. Distinguish absent subclaim score/status/axes from parent C with 50 points, Unknown safety and unrecorded precision. Do not convert large F/P or partial-effect statistics to direct score differences, CIs, importance thresholds or laughter-specific effects. Do not transfer other measures, cortisol, video, brief exposure or original samples to the same PSS effects/denominators. Create no new effects, CIs, totals, independence/safety certification or yoga/medical instructions.", "criterion": "Material for Production methodology materials and review status must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.", "basis": "Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.", "condition_origin": "Internally applied conditions preserved for the existing subclaim. They do not establish preregistration, official-tool certification or completed content review.", "proposed_research": "Material needed: Individual methods and external content review and quality testing were not performed; the existing pending-review state is retained. This records needed materials; no new research was executed." }, { "item_id": "N44", "question_type": "Evidence condition", "question": "What materials would update these gaps?", "needed": "Direct results, analysis plans, overlap and harms data", "role": "Required", "role_reason": "This condition connects Direct results, analysis plans, overlap and harms data with populations, programs, actual controls, measures, timing, denominators, models, prespecification, direct effects/CIs or harms for nonclinical perceived stress, distinguishing other mental-symptom measures, biomarkers and treatment claims.", "application_exception": "Preserve original subclaim C, positive signals and no-intervention/prespecification/blinding gaps. Distinguish absent subclaim score/status/axes from parent C with 50 points, Unknown safety and unrecorded precision. Do not convert large F/P or partial-effect statistics to direct score differences, CIs, importance thresholds or laughter-specific effects. Do not transfer other measures, cortisol, video, brief exposure or original samples to the same PSS effects/denominators. Create no new effects, CIs, totals, independence/safety certification or yoga/medical instructions.", "criterion": "Material for Direct results, analysis plans, overlap and harms data must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.", "basis": "Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.", "condition_origin": "Internally applied conditions preserved for the existing subclaim. They do not establish preregistration, official-tool certification or completed content review.", "proposed_research": "Material needed: Direct PSS tables, estimates and confidence intervals, conflicting tests and models, active controls, schedules, registration, study overlap and exposure and harms materials are needed. This records needed materials; no new research was executed." } ] }