{
  "schema_version": "chamgap-public-evidence-check-1.0",
  "public_id": "v3002-s0",
  "verdict_number": "3002",
  "title": "30% MVC handgrip × supervised office SBP: evidence checklist",
  "view_version": "1.0",
  "view_created_date": "2026-10-18",
  "criteria_version": "1.0",
  "criteria_date": "2026-10-06",
  "review_date": null,
  "legacy_evidence_date": "2026-09-07",
  "review_scope": {
    "materials_read": "Existing review summaries and stored records of methodological application",
    "clinical_papers_directly_read": false,
    "new_clinical_search": false,
    "limitation": "Existing stored summary and preserved methodology application records. External papers, abstracts, registration, protocols, SAPs, original result tables and support disclosures are unread, and review of existing content remains incomplete.",
    "date_meaning": "This is the date the stored materials were checked, not the date of a new search of the clinical literature."
  },
  "claim_context": {
    "population": "Farah randomized 72 treated participants with hypertension; Palmeira has 63 primary-care participants with hypertension; the 2024 report has 84 older home-training participants. Arm eligibility, baseline control, medication changes, comorbidities and outcome-specific analysis denominators are unverified. Do not add these different participant counts.",
    "intervention": "Isometric handgrip training referenced to maximal voluntary contraction (MVC). Distinguish supervised delivery from unsupervised home training. Supervisory contact, actual intensity, devices, adherence and component contributions are unverified. Do not transfer supervised results to home training.",
    "dose": "Original representative study conditions are 30% MVC, 4 holds of 2 minutes, 3 times weekly. Actual exposure, adherence and discontinuation are unverified. Calculate no new total time/exposure and do not turn these into personal exercise/breathing procedures, medication reduction/replacement or treatment instructions.",
    "comparator": "Distinguish Farah supervised, home and no-exercise 3-arm conditions. Original 5% MVC sham, no-exercise and aerobic controls concern different trial contexts; do not fill in the same comparator for every report. Arm contact, exposure, medication/lifestyle care and adjusted effects for specific comparisons are unverified.",
    "endpoint": "The selection is supervised office SBP. Farah office SBP P=.041 and DBP P=.049 are omnibus 3-arm group-by-time tests; a specific adjusted pairwise effect/95% CI is unverified. Distinguish the same trial's null 24-hour ambulatory SBP P=.650/DBP P=.340 and office, central and home measurements.",
    "duration": "Key Farah and Palmeira trials span 12 weeks. Exact duration of 2024 home training, detailed outcome timing, post-training persistence, long-term harms and clinical events are unverified. Do not turn a 24-hour measurement window into training duration or all-day benefit.",
    "excluded_extensions": [
      "Turning a 3-arm omnibus test or within-group reduction into a specific adjusted pairwise effect/CI",
      "Combining office SBP/DBP, central, home, 24-hour and day/night results into one effect",
      "Extending supervised signals into unsupervised home training, all-day pressure reduction or medication replacement",
      "Turning null results into exact effect 0, equivalence or safety certification",
      "Arbitrarily resolving figure/table arm-label inconsistencies or creating new numbers, CIs or totals",
      "Using shared reports/participants, academic support or parent C with 50 points as new independence, precision or subclaim scores",
      "Creating new exercise methods, breathing procedures, medication reduction/replacement or treatment instructions"
    ]
  },
  "requirements": [
    {
      "item_id": "N01",
      "question_type": "Evidence condition",
      "question": "Which supervised office-SBP claim is selected?",
      "needed": "Selected claim, grade, note and measurement-setting boundaries",
      "role": "Required",
      "role_reason": "This condition connects Selected claim, grade, note and measurement-setting boundaries with supervised office SBP, omnibus tests, specific comparisons, within-group changes, measurement settings, denominators, attrition, directness and harm boundaries.",
      "application_exception": "Preserve selected C and the note supporting the direction in small trials while specific adjusted effects remain unverified. Distinguish absent subclaim score/status/axes from parent C with 50 points. Omnibus tests, within-group changes and other measurement settings do not become new specific effects, CIs or independent replication. Create no new grades, safety certification or exercise, breathing, medication or treatment instructions.",
      "criterion": "Material for Selected claim, grade, note and measurement-setting boundaries must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.",
      "basis": "Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.",
      "condition_origin": "Internally applied conditions preserved for the existing subclaim. They do not establish preregistration, official-tool certification or completed content review.",
      "proposed_research": "Material needed: Supervision, comparator, timing, denominators and adjusted direct effects/CIs are unverified. Create no new independent claims or scores. This records needed materials; no new research was executed.",
      "current_reports": [
        "R01",
        "R02",
        "R03"
      ],
      "existence": "Display information in the original parent stored summary is preserved. Public availability, acquisition and actual reading of detailed external material are separately unverified.",
      "acquired_read": "Stored summary read; external abstracts, full texts, registration, protocols, SAPs and support disclosures unread",
      "observation": "The selection is lower supervised office SBP. Preserve original grade C and the note supporting direction in small trials with incomplete specific adjusted effects. Home training, home pressure and 24-hour ambulatory pressure are separate.",
      "condition_status": "Partly verified",
      "status_reason": "The selected claim, parent material and reports are distinguished and transferred from the stored summary. Detailed original material is unverified and review of existing content remains incomplete. This does not establish completed clinical review or certification.",
      "missingness": "Supervision, comparator, timing, denominators and adjusted direct effects/CIs are unverified. Create no new independent claims or scores.",
      "uncertainty": "External original material is unread and review of existing content remains incomplete. Original grades, scores, axes, historical verification and independence statements are not treated as new verdicts or certification.",
      "review_date": null,
      "reading_status": "Full text not read · Stored summary read",
      "additional_material": "Supervision, comparator, timing, denominators and adjusted direct effects/CIs are unverified. Create no new independent claims or scores."
    },
    {
      "item_id": "N02",
      "question_type": "Evidence condition",
      "question": "What is Farah's office-SBP test across 3 arms?",
      "needed": "Omnibus group-by-time test, original model and denominators",
      "role": "Required",
      "role_reason": "This condition connects Omnibus group-by-time test, original model and denominators with supervised office SBP, omnibus tests, specific comparisons, within-group changes, measurement settings, denominators, attrition, directness and harm boundaries.",
      "application_exception": "Preserve selected C and the note supporting the direction in small trials while specific adjusted effects remain unverified. Distinguish absent subclaim score/status/axes from parent C with 50 points. Omnibus tests, within-group changes and other measurement settings do not become new specific effects, CIs or independent replication. Create no new grades, safety certification or exercise, breathing, medication or treatment instructions.",
      "criterion": "Material for Omnibus group-by-time test, original model and denominators must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.",
      "basis": "Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.",
      "condition_origin": "Internally applied conditions preserved for the existing subclaim. They do not establish preregistration, official-tool certification or completed content review.",
      "proposed_research": "Material needed: Original models, arm/time values, adjusted pairwise comparisons, denominators, direct effects/95% CIs and multiple comparisons are unverified. This P alone does not establish specific pairwise effects. This records needed materials; no new research was executed.",
      "current_reports": [
        "R01"
      ],
      "existence": "Display information in the original parent stored summary is preserved. Public availability, acquisition and actual reading of detailed external material are separately unverified.",
      "acquired_read": "Stored summary read; external abstracts, full texts, registration, protocols, SAPs and support disclosures unread",
      "observation": "Preserve office SBP P=.041 in 72 randomized treated participants with hypertension over 12 weeks in supervised/home/no-exercise 3-arm conditions. The original text describes this as an omnibus group-by-time test.",
      "condition_status": "Partly verified",
      "status_reason": "The selected claim, parent material and reports are distinguished and transferred from the stored summary. Detailed original material is unverified and review of existing content remains incomplete. This does not establish completed clinical review or certification.",
      "missingness": "Original models, arm/time values, adjusted pairwise comparisons, denominators, direct effects/95% CIs and multiple comparisons are unverified. This P alone does not establish specific pairwise effects.",
      "uncertainty": "External original material is unread and review of existing content remains incomplete. Original grades, scores, axes, historical verification and independence statements are not treated as new verdicts or certification.",
      "review_date": null,
      "reading_status": "Full text not read · Stored summary read",
      "additional_material": "Original models, arm/time values, adjusted pairwise comparisons, denominators, direct effects/95% CIs and multiple comparisons are unverified. This P alone does not establish specific pairwise effects."
    },
    {
      "item_id": "N03",
      "question_type": "Evidence condition",
      "question": "Which pairwise difference does the omnibus test establish?",
      "needed": "Omnibus 3-arm testing versus specific adjusted comparisons",
      "role": "Required",
      "role_reason": "This condition connects Omnibus 3-arm testing versus specific adjusted comparisons with supervised office SBP, omnibus tests, specific comparisons, within-group changes, measurement settings, denominators, attrition, directness and harm boundaries.",
      "application_exception": "Preserve selected C and the note supporting the direction in small trials while specific adjusted effects remain unverified. Distinguish absent subclaim score/status/axes from parent C with 50 points. Omnibus tests, within-group changes and other measurement settings do not become new specific effects, CIs or independent replication. Create no new grades, safety certification or exercise, breathing, medication or treatment instructions.",
      "criterion": "Material for Omnibus 3-arm testing versus specific adjusted comparisons must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.",
      "basis": "Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.",
      "condition_origin": "Internally applied conditions preserved for the existing subclaim. They do not establish preregistration, official-tool certification or completed content review.",
      "proposed_research": "Material needed: Planned comparisons, baseline adjustment, estimates/CIs, denominators, analysis populations and original tables are unverified. Do not fill in absent pairwise values, CIs or P. This records needed materials; no new research was executed.",
      "current_reports": [
        "R01"
      ],
      "existence": "Display information in the original parent stored summary is preserved. Public availability, acquisition and actual reading of detailed external material are separately unverified.",
      "acquired_read": "Stored summary read; external abstracts, full texts, registration, protocols, SAPs and support disclosures unread",
      "observation": "P=.041 for the 3-arm/time test does not show that supervised/no-exercise, supervised/home and home/no-exercise comparisons all have the same effect or significance.",
      "condition_status": "Partly verified",
      "status_reason": "The selected claim, parent material and reports are distinguished and transferred from the stored summary. Detailed original material is unverified and review of existing content remains incomplete. This does not establish completed clinical review or certification.",
      "missingness": "Planned comparisons, baseline adjustment, estimates/CIs, denominators, analysis populations and original tables are unverified. Do not fill in absent pairwise values, CIs or P.",
      "uncertainty": "External original material is unread and review of existing content remains incomplete. Original grades, scores, axes, historical verification and independence statements are not treated as new verdicts or certification.",
      "review_date": null,
      "reading_status": "Full text not read · Stored summary read",
      "additional_material": "Planned comparisons, baseline adjustment, estimates/CIs, denominators, analysis populations and original tables are unverified. Do not fill in absent pairwise values, CIs or P."
    },
    {
      "item_id": "N04",
      "question_type": "Evidence condition",
      "question": "Can SBP and DBP tests be combined?",
      "needed": "Office systolic/diastolic outcomes and precision",
      "role": "Required",
      "role_reason": "This condition connects Office systolic/diastolic outcomes and precision with supervised office SBP, omnibus tests, specific comparisons, within-group changes, measurement settings, denominators, attrition, directness and harm boundaries.",
      "application_exception": "Preserve selected C and the note supporting the direction in small trials while specific adjusted effects remain unverified. Distinguish absent subclaim score/status/axes from parent C with 50 points. Omnibus tests, within-group changes and other measurement settings do not become new specific effects, CIs or independent replication. Create no new grades, safety certification or exercise, breathing, medication or treatment instructions.",
      "criterion": "Material for Office systolic/diastolic outcomes and precision must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.",
      "basis": "Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.",
      "condition_origin": "Internally applied conditions preserved for the existing subclaim. They do not establish preregistration, official-tool certification or completed content review.",
      "proposed_research": "Material needed: Original arm values, specific comparisons, CIs, denominators, planned hierarchy and multiple testing are unverified. Do not copy DBP results into SBP effects. This records needed materials; no new research was executed.",
      "current_reports": [
        "R01"
      ],
      "existence": "Display information in the original parent stored summary is preserved. Public availability, acquisition and actual reading of detailed external material are separately unverified.",
      "acquired_read": "Stored summary read; external abstracts, full texts, registration, protocols, SAPs and support disclosures unread",
      "observation": "Farah office DBP P=.049 and SBP P=.041 are omnibus tests for different endpoints. Significant DBP also differs from a specific adjusted pairwise difference or everyday pressure benefit.",
      "condition_status": "Partly verified",
      "status_reason": "The selected claim, parent material and reports are distinguished and transferred from the stored summary. Detailed original material is unverified and review of existing content remains incomplete. This does not establish completed clinical review or certification.",
      "missingness": "Original arm values, specific comparisons, CIs, denominators, planned hierarchy and multiple testing are unverified. Do not copy DBP results into SBP effects.",
      "uncertainty": "External original material is unread and review of existing content remains incomplete. Original grades, scores, axes, historical verification and independence statements are not treated as new verdicts or certification.",
      "review_date": null,
      "reading_status": "Full text not read · Stored summary read",
      "additional_material": "Original arm values, specific comparisons, CIs, denominators, planned hierarchy and multiple testing are unverified. Do not copy DBP results into SBP effects."
    },
    {
      "item_id": "N05",
      "question_type": "Evidence condition",
      "question": "Are office, central and ambulatory pressure the same outcome?",
      "needed": "Measurement locations, settings, devices, timing and denominators",
      "role": "Required",
      "role_reason": "This condition connects Measurement locations, settings, devices, timing and denominators with supervised office SBP, omnibus tests, specific comparisons, within-group changes, measurement settings, denominators, attrition, directness and harm boundaries.",
      "application_exception": "Preserve selected C and the note supporting the direction in small trials while specific adjusted effects remain unverified. Distinguish absent subclaim score/status/axes from parent C with 50 points. Omnibus tests, within-group changes and other measurement settings do not become new specific effects, CIs or independent replication. Create no new grades, safety certification or exercise, breathing, medication or treatment instructions.",
      "criterion": "Material for Measurement locations, settings, devices, timing and denominators must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.",
      "basis": "Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.",
      "condition_origin": "Internally applied conditions preserved for the existing subclaim. They do not establish preregistration, official-tool certification or completed content review.",
      "proposed_research": "Material needed: Locations, devices, conditions, timing, denominators, between-group comparisons/CIs and planned hierarchy are unverified. Do not estimate central values or combine all as the same SBP effect. This records needed materials; no new research was executed.",
      "current_reports": [
        "R01"
      ],
      "existence": "Display information in the original parent stored summary is preserved. Public availability, acquisition and actual reading of detailed external material are separately unverified.",
      "acquired_read": "Stored summary read; external abstracts, full texts, registration, protocols, SAPs and support disclosures unread",
      "observation": "Farah covers office, central and 24-hour ambulatory pressure, and its bibliography mentions brachial/central pressure. Original P values concern office and ambulatory outcomes; exact central-pressure effects/CIs are not provided.",
      "condition_status": "Partly verified",
      "status_reason": "The selected claim, parent material and reports are distinguished and transferred from the stored summary. Detailed original material is unverified and review of existing content remains incomplete. This does not establish completed clinical review or certification.",
      "missingness": "Locations, devices, conditions, timing, denominators, between-group comparisons/CIs and planned hierarchy are unverified. Do not estimate central values or combine all as the same SBP effect.",
      "uncertainty": "External original material is unread and review of existing content remains incomplete. Original grades, scores, axes, historical verification and independence statements are not treated as new verdicts or certification.",
      "review_date": null,
      "reading_status": "Full text not read · Stored summary read",
      "additional_material": "Locations, devices, conditions, timing, denominators, between-group comparisons/CIs and planned hierarchy are unverified. Do not estimate central values or combine all as the same SBP effect."
    },
    {
      "item_id": "N06",
      "question_type": "Evidence condition",
      "question": "Is a within-group reduction an added benefit over control?",
      "needed": "Within-group changes versus direct between-group effects",
      "role": "Required",
      "role_reason": "This condition connects Within-group changes versus direct between-group effects with supervised office SBP, omnibus tests, specific comparisons, within-group changes, measurement settings, denominators, attrition, directness and harm boundaries.",
      "application_exception": "Preserve selected C and the note supporting the direction in small trials while specific adjusted effects remain unverified. Distinguish absent subclaim score/status/axes from parent C with 50 points. Omnibus tests, within-group changes and other measurement settings do not become new specific effects, CIs or independent replication. Create no new grades, safety certification or exercise, breathing, medication or treatment instructions.",
      "criterion": "Material for Within-group changes versus direct between-group effects must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.",
      "basis": "Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.",
      "condition_origin": "Internally applied conditions preserved for the existing subclaim. They do not establish preregistration, official-tool certification or completed content review.",
      "proposed_research": "Material needed: Baseline/follow-up values, adjusted models, specific comparisons, arm denominators and original effects/CIs are unverified. Do not subtract changes to create new control-relative effects. This records needed materials; no new research was executed.",
      "current_reports": [
        "R01",
        "R02",
        "R03"
      ],
      "existence": "Display information in the original parent stored summary is preserved. Public availability, acquisition and actual reading of detailed external material are separately unverified.",
      "acquired_read": "Stored summary read; external abstracts, full texts, registration, protocols, SAPs and support disclosures unread",
      "observation": "The original text does not turn within-group reductions into specific between-group effects. Distinguish directional supervised office signals from baseline/follow-up changes.",
      "condition_status": "Partly verified",
      "status_reason": "The selected claim, parent material and reports are distinguished and transferred from the stored summary. Detailed original material is unverified and review of existing content remains incomplete. This does not establish completed clinical review or certification.",
      "missingness": "Baseline/follow-up values, adjusted models, specific comparisons, arm denominators and original effects/CIs are unverified. Do not subtract changes to create new control-relative effects.",
      "uncertainty": "External original material is unread and review of existing content remains incomplete. Original grades, scores, axes, historical verification and independence statements are not treated as new verdicts or certification.",
      "review_date": null,
      "reading_status": "Full text not read · Stored summary read",
      "additional_material": "Baseline/follow-up values, adjusted models, specific comparisons, arm denominators and original effects/CIs are unverified. Do not subtract changes to create new control-relative effects."
    },
    {
      "item_id": "N07",
      "question_type": "Evidence condition",
      "question": "Were figure/table arm-label inconsistencies resolved?",
      "needed": "Original figures, tables, legends and arm attribution",
      "role": "Required",
      "role_reason": "This condition connects Original figures, tables, legends and arm attribution with supervised office SBP, omnibus tests, specific comparisons, within-group changes, measurement settings, denominators, attrition, directness and harm boundaries.",
      "application_exception": "Preserve selected C and the note supporting the direction in small trials while specific adjusted effects remain unverified. Distinguish absent subclaim score/status/axes from parent C with 50 points. Omnibus tests, within-group changes and other measurement settings do not become new specific effects, CIs or independent replication. Create no new grades, safety certification or exercise, breathing, medication or treatment instructions.",
      "criterion": "Material for Original figures, tables, legends and arm attribution must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.",
      "basis": "Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.",
      "condition_origin": "Internally applied conditions preserved for the existing subclaim. They do not establish preregistration, official-tool certification or completed content review.",
      "proposed_research": "Material needed: Complete original figures/tables, legends, arm keys, underlying data, explanations and corrections are needed. Production did not resolve these inconsistencies or edit values. This records needed materials; no new research was executed.",
      "current_reports": [
        "R01"
      ],
      "existence": "Display information in the original parent stored summary is preserved. Public availability, acquisition and actual reading of detailed external material are separately unverified.",
      "acquired_read": "Stored summary read; external abstracts, full texts, registration, protocols, SAPs and support disclosures unread",
      "observation": "Original explanations and bibliographic notes identify figure/table arm-label inconsistencies. Do not arbitrarily assign numbers to arms and read them as specific pairwise effects.",
      "condition_status": "Partly verified",
      "status_reason": "The selected claim, parent material and reports are distinguished and transferred from the stored summary. Detailed original material is unverified and review of existing content remains incomplete. This does not establish completed clinical review or certification.",
      "missingness": "Complete original figures/tables, legends, arm keys, underlying data, explanations and corrections are needed. Production did not resolve these inconsistencies or edit values.",
      "uncertainty": "External original material is unread and review of existing content remains incomplete. Original grades, scores, axes, historical verification and independence statements are not treated as new verdicts or certification.",
      "review_date": null,
      "reading_status": "Full text not read · Stored summary read",
      "additional_material": "Complete original figures/tables, legends, arm keys, underlying data, explanations and corrections are needed. Production did not resolve these inconsistencies or edit values."
    },
    {
      "item_id": "N08",
      "question_type": "Evidence condition",
      "question": "What were Palmeira's supportive and null results?",
      "needed": "Office-SBP interaction versus DBP and ambulatory pressure",
      "role": "Required",
      "role_reason": "This condition connects Office-SBP interaction versus DBP and ambulatory pressure with supervised office SBP, omnibus tests, specific comparisons, within-group changes, measurement settings, denominators, attrition, directness and harm boundaries.",
      "application_exception": "Preserve selected C and the note supporting the direction in small trials while specific adjusted effects remain unverified. Distinguish absent subclaim score/status/axes from parent C with 50 points. Omnibus tests, within-group changes and other measurement settings do not become new specific effects, CIs or independent replication. Create no new grades, safety certification or exercise, breathing, medication or treatment instructions.",
      "criterion": "Material for Office-SBP interaction versus DBP and ambulatory pressure must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.",
      "basis": "Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.",
      "condition_origin": "Internally applied conditions preserved for the existing subclaim. They do not establish preregistration, official-tool certification or completed content review.",
      "proposed_research": "Material needed: Original models, arm denominators, baseline/follow-up, endpoint comparisons/CIs and planned analyses are unverified. Do not copy Farah P into this report. This records needed materials; no new research was executed.",
      "current_reports": [
        "R02"
      ],
      "existence": "Display information in the original parent stored summary is preserved. Public availability, acquisition and actual reading of detailed external material are separately unverified.",
      "acquired_read": "Stored summary read; external abstracts, full texts, registration, protocols, SAPs and support disclosures unread",
      "observation": "Palmeira is preserved as a 63-participant, 12-week randomized trial with positive office-SBP interaction and null DBP/ambulatory pressure. Exact SBP effects/CIs, P and arm denominators are absent from the summary.",
      "condition_status": "Partly verified",
      "status_reason": "The selected claim, parent material and reports are distinguished and transferred from the stored summary. Detailed original material is unverified and review of existing content remains incomplete. This does not establish completed clinical review or certification.",
      "missingness": "Original models, arm denominators, baseline/follow-up, endpoint comparisons/CIs and planned analyses are unverified. Do not copy Farah P into this report.",
      "uncertainty": "External original material is unread and review of existing content remains incomplete. Original grades, scores, axes, historical verification and independence statements are not treated as new verdicts or certification.",
      "review_date": null,
      "reading_status": "Full text not read · Stored summary read",
      "additional_material": "Original models, arm denominators, baseline/follow-up, endpoint comparisons/CIs and planned analyses are unverified. Do not copy Farah P into this report."
    },
    {
      "item_id": "N09",
      "question_type": "Evidence condition",
      "question": "Were large attrition and analysis denominators verified?",
      "needed": "Randomization, completion, missingness, ITT, sensitivity and time-specific denominators",
      "role": "Required",
      "role_reason": "This condition connects Randomization, completion, missingness, ITT, sensitivity and time-specific denominators with supervised office SBP, omnibus tests, specific comparisons, within-group changes, measurement settings, denominators, attrition, directness and harm boundaries.",
      "application_exception": "Preserve selected C and the note supporting the direction in small trials while specific adjusted effects remain unverified. Distinguish absent subclaim score/status/axes from parent C with 50 points. Omnibus tests, within-group changes and other measurement settings do not become new specific effects, CIs or independent replication. Create no new grades, safety certification or exercise, breathing, medication or treatment instructions.",
      "criterion": "Material for Randomization, completion, missingness, ITT, sensitivity and time-specific denominators must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.",
      "basis": "Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.",
      "condition_origin": "Internally applied conditions preserved for the existing subclaim. They do not establish preregistration, official-tool certification or completed content review.",
      "proposed_research": "Material needed: Original flow charts, arm allocation/completion, missingness/withdrawal reasons, ITT, analyses, sensitivity and time-specific denominators are unverified. Calculate no new withdrawal counts, rates or effects. This records needed materials; no new research was executed.",
      "current_reports": [
        "R02"
      ],
      "existence": "Display information in the original parent stored summary is preserved. Public availability, acquisition and actual reading of detailed external material are separately unverified.",
      "acquired_read": "Stored summary read; external abstracts, full texts, registration, protocols, SAPs and support disclosures unread",
      "observation": "Palmeira bibliography records 63 participants and large attrition. Exact completion/analysis counts, arm imbalances and missing-data handling are absent from the summary. Do not treat all participants as completers for every endpoint.",
      "condition_status": "Partly verified",
      "status_reason": "The selected claim, parent material and reports are distinguished and transferred from the stored summary. Detailed original material is unverified and review of existing content remains incomplete. This does not establish completed clinical review or certification.",
      "missingness": "Original flow charts, arm allocation/completion, missingness/withdrawal reasons, ITT, analyses, sensitivity and time-specific denominators are unverified. Calculate no new withdrawal counts, rates or effects.",
      "uncertainty": "External original material is unread and review of existing content remains incomplete. Original grades, scores, axes, historical verification and independence statements are not treated as new verdicts or certification.",
      "review_date": null,
      "reading_status": "Full text not read · Stored summary read",
      "additional_material": "Original flow charts, arm allocation/completion, missingness/withdrawal reasons, ITT, analyses, sensitivity and time-specific denominators are unverified. Calculate no new withdrawal counts, rates or effects."
    },
    {
      "item_id": "N10",
      "question_type": "Evidence condition",
      "question": "Can supervised results be transferred to home training?",
      "needed": "Training location, supervision, contact, actual exposure and adherence",
      "role": "Required",
      "role_reason": "This condition connects Training location, supervision, contact, actual exposure and adherence with supervised office SBP, omnibus tests, specific comparisons, within-group changes, measurement settings, denominators, attrition, directness and harm boundaries.",
      "application_exception": "Preserve selected C and the note supporting the direction in small trials while specific adjusted effects remain unverified. Distinguish absent subclaim score/status/axes from parent C with 50 points. Omnibus tests, within-group changes and other measurement settings do not become new specific effects, CIs or independent replication. Create no new grades, safety certification or exercise, breathing, medication or treatment instructions.",
      "criterion": "Material for Training location, supervision, contact, actual exposure and adherence must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.",
      "basis": "Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.",
      "condition_origin": "Internally applied conditions preserved for the existing subclaim. They do not establish preregistration, official-tool certification or completed content review.",
      "proposed_research": "Material needed: Actual intensity, exposure, contact, adherence, comparators and original comparisons/denominators are unverified. Do not equate supervised/home conditions or create new exercise methods. This records needed materials; no new research was executed.",
      "current_reports": [
        "R01",
        "R03"
      ],
      "existence": "Display information in the original parent stored summary is preserved. Public availability, acquisition and actual reading of detailed external material are separately unverified.",
      "acquired_read": "Stored summary read; external abstracts, full texts, registration, protocols, SAPs and support disclosures unread",
      "observation": "The original text does not transfer supervised results to unsupervised home training. Distinguish Farah 3-arm conditions from null results in the 2024 home-training report with 84 participants.",
      "condition_status": "Partly verified",
      "status_reason": "The selected claim, parent material and reports are distinguished and transferred from the stored summary. Detailed original material is unverified and review of existing content remains incomplete. This does not establish completed clinical review or certification.",
      "missingness": "Actual intensity, exposure, contact, adherence, comparators and original comparisons/denominators are unverified. Do not equate supervised/home conditions or create new exercise methods.",
      "uncertainty": "External original material is unread and review of existing content remains incomplete. Original grades, scores, axes, historical verification and independence statements are not treated as new verdicts or certification.",
      "review_date": null,
      "reading_status": "Full text not read · Stored summary read",
      "additional_material": "Actual intensity, exposure, contact, adherence, comparators and original comparisons/denominators are unverified. Do not equate supervised/home conditions or create new exercise methods."
    },
    {
      "item_id": "N11",
      "question_type": "Evidence condition",
      "question": "Are home training and home pressure measurement the same?",
      "needed": "Intervention delivery location versus outcome measurement setting",
      "role": "Required",
      "role_reason": "This condition connects Intervention delivery location versus outcome measurement setting with supervised office SBP, omnibus tests, specific comparisons, within-group changes, measurement settings, denominators, attrition, directness and harm boundaries.",
      "application_exception": "Preserve selected C and the note supporting the direction in small trials while specific adjusted effects remain unverified. Distinguish absent subclaim score/status/axes from parent C with 50 points. Omnibus tests, within-group changes and other measurement settings do not become new specific effects, CIs or independent replication. Create no new grades, safety certification or exercise, breathing, medication or treatment instructions.",
      "criterion": "Material for Intervention delivery location versus outcome measurement setting must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.",
      "basis": "Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.",
      "condition_origin": "Internally applied conditions preserved for the existing subclaim. They do not establish preregistration, official-tool certification or completed content review.",
      "proposed_research": "Material needed: Original data separating training location/supervision from measurement location, devices, schedules, denominators, timing and specific comparisons are needed. Exact home-pressure effects are absent from the summary. This records needed materials; no new research was executed.",
      "current_reports": [
        "R01",
        "R02",
        "R03"
      ],
      "existence": "Display information in the original parent stored summary is preserved. Public availability, acquisition and actual reading of detailed external material are separately unverified.",
      "acquired_read": "Stored summary read; external abstracts, full texts, registration, protocols, SAPs and support disclosures unread",
      "observation": "The original text distinguishes home-training conditions from office, home and 24-hour measurements. Training at home does not establish a comparison using home-pressure values.",
      "condition_status": "Partly verified",
      "status_reason": "The selected claim, parent material and reports are distinguished and transferred from the stored summary. Detailed original material is unverified and review of existing content remains incomplete. This does not establish completed clinical review or certification.",
      "missingness": "Original data separating training location/supervision from measurement location, devices, schedules, denominators, timing and specific comparisons are needed. Exact home-pressure effects are absent from the summary.",
      "uncertainty": "External original material is unread and review of existing content remains incomplete. Original grades, scores, axes, historical verification and independence statements are not treated as new verdicts or certification.",
      "review_date": null,
      "reading_status": "Full text not read · Stored summary read",
      "additional_material": "Original data separating training location/supervision from measurement location, devices, schedules, denominators, timing and specific comparisons are needed. Exact home-pressure effects are absent from the summary."
    },
    {
      "item_id": "N12",
      "question_type": "Evidence condition",
      "question": "How does null 24-hour pressure limit the office signal?",
      "needed": "Setting-specific tests, original values, between-group effects and denominators",
      "role": "Required",
      "role_reason": "This condition connects Setting-specific tests, original values, between-group effects and denominators with supervised office SBP, omnibus tests, specific comparisons, within-group changes, measurement settings, denominators, attrition, directness and harm boundaries.",
      "application_exception": "Preserve selected C and the note supporting the direction in small trials while specific adjusted effects remain unverified. Distinguish absent subclaim score/status/axes from parent C with 50 points. Omnibus tests, within-group changes and other measurement settings do not become new specific effects, CIs or independent replication. Create no new grades, safety certification or exercise, breathing, medication or treatment instructions.",
      "criterion": "Material for Setting-specific tests, original values, between-group effects and denominators must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.",
      "basis": "Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.",
      "condition_origin": "Internally applied conditions preserved for the existing subclaim. They do not establish preregistration, official-tool certification or completed content review.",
      "proposed_research": "Material needed: Setting-specific original values, between-group CIs, denominators, devices, valid measurements, timing and effects of interest are unverified. Null does not certify exact effect 0 or equivalence. This records needed materials; no new research was executed.",
      "current_reports": [
        "R01",
        "R02",
        "R03"
      ],
      "existence": "Display information in the original parent stored summary is preserved. Public availability, acquisition and actual reading of detailed external material are separately unverified.",
      "acquired_read": "Stored summary read; external abstracts, full texts, registration, protocols, SAPs and support disclosures unread",
      "observation": "In the same Farah trial, 24-hour ambulatory SBP P=.650 and DBP P=.340 are null. Do not extend office signals into all-day pressure reduction.",
      "condition_status": "Partly verified",
      "status_reason": "The selected claim, parent material and reports are distinguished and transferred from the stored summary. Detailed original material is unverified and review of existing content remains incomplete. This does not establish completed clinical review or certification.",
      "missingness": "Setting-specific original values, between-group CIs, denominators, devices, valid measurements, timing and effects of interest are unverified. Null does not certify exact effect 0 or equivalence.",
      "uncertainty": "External original material is unread and review of existing content remains incomplete. Original grades, scores, axes, historical verification and independence statements are not treated as new verdicts or certification.",
      "review_date": null,
      "reading_status": "Full text not read · Stored summary read",
      "additional_material": "Setting-specific original values, between-group CIs, denominators, devices, valid measurements, timing and effects of interest are unverified. Null does not certify exact effect 0 or equivalence."
    },
    {
      "item_id": "N13",
      "question_type": "Evidence condition",
      "question": "Does office SBP establish day/night or clinical-event benefit?",
      "needed": "Surrogates, day/night/ambulatory pressure and long-term clinical-event boundaries",
      "role": "Required",
      "role_reason": "This condition connects Surrogates, day/night/ambulatory pressure and long-term clinical-event boundaries with supervised office SBP, omnibus tests, specific comparisons, within-group changes, measurement settings, denominators, attrition, directness and harm boundaries.",
      "application_exception": "Preserve selected C and the note supporting the direction in small trials while specific adjusted effects remain unverified. Distinguish absent subclaim score/status/axes from parent C with 50 points. Omnibus tests, within-group changes and other measurement settings do not become new specific effects, CIs or independent replication. Create no new grades, safety certification or exercise, breathing, medication or treatment instructions.",
      "criterion": "Material for Surrogates, day/night/ambulatory pressure and long-term clinical-event boundaries must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.",
      "basis": "Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.",
      "condition_origin": "Internally applied conditions preserved for the existing subclaim. They do not establish preregistration, official-tool certification or completed content review.",
      "proposed_research": "Material needed: Day/night definitions, measurements/denominators, between-group effects/CIs, clinical importance and direct long-term event data are needed. Create no new medication reduction/replacement or treatment instructions. This records needed materials; no new research was executed.",
      "current_reports": [
        "R01",
        "R02",
        "R03"
      ],
      "existence": "Display information in the original parent stored summary is preserved. Public availability, acquisition and actual reading of detailed external material are separately unverified.",
      "acquired_read": "Stored summary read; external abstracts, full texts, registration, protocols, SAPs and support disclosures unread",
      "observation": "The original text limits conclusions by measurement setting and surrogate outcomes; office results do not establish everyday pressure benefit or medication replacement. Direct day/night or disease-event effects/CIs are absent.",
      "condition_status": "Partly verified",
      "status_reason": "The selected claim, parent material and reports are distinguished and transferred from the stored summary. Detailed original material is unverified and review of existing content remains incomplete. This does not establish completed clinical review or certification.",
      "missingness": "Day/night definitions, measurements/denominators, between-group effects/CIs, clinical importance and direct long-term event data are needed. Create no new medication reduction/replacement or treatment instructions.",
      "uncertainty": "External original material is unread and review of existing content remains incomplete. Original grades, scores, axes, historical verification and independence statements are not treated as new verdicts or certification.",
      "review_date": null,
      "reading_status": "Full text not read · Stored summary read",
      "additional_material": "Day/night definitions, measurements/denominators, between-group effects/CIs, clinical importance and direct long-term event data are needed. Create no new medication reduction/replacement or treatment instructions."
    },
    {
      "item_id": "N14",
      "question_type": "Evidence condition",
      "question": "Do signals across studies establish precise independent replication?",
      "needed": "Matched supervision/controls, institutions, recruitment and report/participant relationships",
      "role": "Required",
      "role_reason": "This condition connects Matched supervision/controls, institutions, recruitment and report/participant relationships with supervised office SBP, omnibus tests, specific comparisons, within-group changes, measurement settings, denominators, attrition, directness and harm boundaries.",
      "application_exception": "Preserve selected C and the note supporting the direction in small trials while specific adjusted effects remain unverified. Distinguish absent subclaim score/status/axes from parent C with 50 points. Omnibus tests, within-group changes and other measurement settings do not become new specific effects, CIs or independent replication. Create no new grades, safety certification or exercise, breathing, medication or treatment instructions.",
      "criterion": "Material for Matched supervision/controls, institutions, recruitment and report/participant relationships must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.",
      "basis": "Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.",
      "condition_origin": "Internally applied conditions preserved for the existing subclaim. They do not establish preregistration, official-tool certification or completed content review.",
      "proposed_research": "Material needed: Institutions, recruitment/registration, support, report/participant overlap, matched supervision/controls and original effects/CIs are unverified. Do not fill in unique-trial/participant totals. This records needed materials; no new research was executed.",
      "current_reports": [
        "R01",
        "R02",
        "R03"
      ],
      "existence": "Display information in the original parent stored summary is preserved. Public availability, acquisition and actual reading of detailed external material are separately unverified.",
      "acquired_read": "Stored summary read; external abstracts, full texts, registration, protocols, SAPs and support disclosures unread",
      "observation": "The original text describes supervised office-SBP signals across trials as a strength. Preserve original I2/R1 axes without upgrading directions from different controls, within-group changes or omnibus tests into new independent confirmation.",
      "condition_status": "Partly verified",
      "status_reason": "The selected claim, parent material and reports are distinguished and transferred from the stored summary. Detailed original material is unverified and review of existing content remains incomplete. This does not establish completed clinical review or certification.",
      "missingness": "Institutions, recruitment/registration, support, report/participant overlap, matched supervision/controls and original effects/CIs are unverified. Do not fill in unique-trial/participant totals.",
      "uncertainty": "External original material is unread and review of existing content remains incomplete. Original grades, scores, axes, historical verification and independence statements are not treated as new verdicts or certification.",
      "review_date": null,
      "reading_status": "Full text not read · Stored summary read",
      "additional_material": "Institutions, recruitment/registration, support, report/participant overlap, matched supervision/controls and original effects/CIs are unverified. Do not fill in unique-trial/participant totals."
    },
    {
      "item_id": "N15",
      "question_type": "Evidence condition",
      "question": "Who were the participants and what was their medication status?",
      "needed": "Diagnosis, baseline control, medication, age, comorbidities and eligibility",
      "role": "Required",
      "role_reason": "This condition connects Diagnosis, baseline control, medication, age, comorbidities and eligibility with supervised office SBP, omnibus tests, specific comparisons, within-group changes, measurement settings, denominators, attrition, directness and harm boundaries.",
      "application_exception": "Preserve selected C and the note supporting the direction in small trials while specific adjusted effects remain unverified. Distinguish absent subclaim score/status/axes from parent C with 50 points. Omnibus tests, within-group changes and other measurement settings do not become new specific effects, CIs or independent replication. Create no new grades, safety certification or exercise, breathing, medication or treatment instructions.",
      "criterion": "Material for Diagnosis, baseline control, medication, age, comorbidities and eligibility must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.",
      "basis": "Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.",
      "condition_origin": "Internally applied conditions preserved for the existing subclaim. They do not establish preregistration, official-tool certification or completed content review.",
      "proposed_research": "Material needed: Diagnosis, baseline control, medication/changes, age, comorbidities, recruitment/exclusions and arm denominators are unverified. Do not extend this to untreated, other-patient or vulnerable populations. This records needed materials; no new research was executed.",
      "current_reports": [
        "R01",
        "R02",
        "R03"
      ],
      "existence": "Display information in the original parent stored summary is preserved. Public availability, acquisition and actual reading of detailed external material are separately unverified.",
      "acquired_read": "Stored summary read; external abstracts, full texts, registration, protocols, SAPs and support disclosures unread",
      "observation": "Farah randomized 72 treated participants with hypertension; Palmeira concerns primary-care hypertension; the 2024 report concerns older home-training participants. Original counts and representative information do not establish identical populations.",
      "condition_status": "Partly verified",
      "status_reason": "The selected claim, parent material and reports are distinguished and transferred from the stored summary. Detailed original material is unverified and review of existing content remains incomplete. This does not establish completed clinical review or certification.",
      "missingness": "Diagnosis, baseline control, medication/changes, age, comorbidities, recruitment/exclusions and arm denominators are unverified. Do not extend this to untreated, other-patient or vulnerable populations.",
      "uncertainty": "External original material is unread and review of existing content remains incomplete. Original grades, scores, axes, historical verification and independence statements are not treated as new verdicts or certification.",
      "review_date": null,
      "reading_status": "Full text not read · Stored summary read",
      "additional_material": "Diagnosis, baseline control, medication/changes, age, comorbidities, recruitment/exclusions and arm denominators are unverified. Do not extend this to untreated, other-patient or vulnerable populations."
    },
    {
      "item_id": "N16",
      "question_type": "Evidence condition",
      "question": "Are representative training conditions instructions?",
      "needed": "Original intensity, exposure, delivery and actual adherence",
      "role": "Supplementary",
      "role_reason": "This condition connects Original intensity, exposure, delivery and actual adherence with supervised office SBP, omnibus tests, specific comparisons, within-group changes, measurement settings, denominators, attrition, directness and harm boundaries.",
      "application_exception": "Preserve selected C and the note supporting the direction in small trials while specific adjusted effects remain unverified. Distinguish absent subclaim score/status/axes from parent C with 50 points. Omnibus tests, within-group changes and other measurement settings do not become new specific effects, CIs or independent replication. Create no new grades, safety certification or exercise, breathing, medication or treatment instructions.",
      "criterion": "Material for Original intensity, exposure, delivery and actual adherence must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.",
      "basis": "Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.",
      "condition_origin": "Internally applied conditions preserved for the existing subclaim. They do not establish preregistration, official-tool certification or completed content review.",
      "proposed_research": "Material needed: Original devices, intensity measurement, exposure/sessions, supervision/contact, adherence and control records are needed. Calculate no new total time/exposure or exercise, breathing or treatment steps. This records needed materials; no new research was executed.",
      "current_reports": [
        "R01",
        "R02",
        "R03"
      ],
      "existence": "Display information in the original parent stored summary is preserved. Public availability, acquisition and actual reading of detailed external material are separately unverified.",
      "acquired_read": "Stored summary read; external abstracts, full texts, registration, protocols, SAPs and support disclosures unread",
      "observation": "Original representative conditions are 30% MVC, 4 holds of 2 minutes, 3 times weekly. Preserve them as study identifiers; actual intensity and adherence are unverified.",
      "condition_status": "Partly verified",
      "status_reason": "The selected claim, parent material and reports are distinguished and transferred from the stored summary. Detailed original material is unverified and review of existing content remains incomplete. This does not establish completed clinical review or certification.",
      "missingness": "Original devices, intensity measurement, exposure/sessions, supervision/contact, adherence and control records are needed. Calculate no new total time/exposure or exercise, breathing or treatment steps.",
      "uncertainty": "External original material is unread and review of existing content remains incomplete. Original grades, scores, axes, historical verification and independence statements are not treated as new verdicts or certification.",
      "review_date": null,
      "reading_status": "Full text not read · Stored summary read",
      "additional_material": "Original devices, intensity measurement, exposure/sessions, supervision/contact, adherence and control records are needed. Calculate no new total time/exposure or exercise, breathing or treatment steps."
    },
    {
      "item_id": "N17",
      "question_type": "Evidence condition",
      "question": "Were different comparators distinguished?",
      "needed": "Sham, no-exercise and aerobic controls and effects of interest",
      "role": "Required",
      "role_reason": "This condition connects Sham, no-exercise and aerobic controls and effects of interest with supervised office SBP, omnibus tests, specific comparisons, within-group changes, measurement settings, denominators, attrition, directness and harm boundaries.",
      "application_exception": "Preserve selected C and the note supporting the direction in small trials while specific adjusted effects remain unverified. Distinguish absent subclaim score/status/axes from parent C with 50 points. Omnibus tests, within-group changes and other measurement settings do not become new specific effects, CIs or independent replication. Create no new grades, safety certification or exercise, breathing, medication or treatment instructions.",
      "criterion": "Material for Sham, no-exercise and aerobic controls and effects of interest must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.",
      "basis": "Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.",
      "condition_origin": "Internally applied conditions preserved for the existing subclaim. They do not establish preregistration, official-tool certification or completed content review.",
      "proposed_research": "Material needed: Report-specific control intensity, exposure, contact, baseline adjustment, planned comparisons and denominators are unverified. Do not interchange comparator-specific effects. This records needed materials; no new research was executed.",
      "current_reports": [
        "R01",
        "R02",
        "R03"
      ],
      "existence": "Display information in the original parent stored summary is preserved. Public availability, acquisition and actual reading of detailed external material are separately unverified.",
      "acquired_read": "Stored summary read; external abstracts, full texts, registration, protocols, SAPs and support disclosures unread",
      "observation": "The original text distinguishes trials of supervised/home training with 5% MVC sham, no-exercise and aerobic controls. Do not fill in the same comparator/blinding conditions for all reports.",
      "condition_status": "Partly verified",
      "status_reason": "The selected claim, parent material and reports are distinguished and transferred from the stored summary. Detailed original material is unverified and review of existing content remains incomplete. This does not establish completed clinical review or certification.",
      "missingness": "Report-specific control intensity, exposure, contact, baseline adjustment, planned comparisons and denominators are unverified. Do not interchange comparator-specific effects.",
      "uncertainty": "External original material is unread and review of existing content remains incomplete. Original grades, scores, axes, historical verification and independence statements are not treated as new verdicts or certification.",
      "review_date": null,
      "reading_status": "Full text not read · Stored summary read",
      "additional_material": "Report-specific control intensity, exposure, contact, baseline adjustment, planned comparisons and denominators are unverified. Do not interchange comparator-specific effects."
    },
    {
      "item_id": "N18",
      "question_type": "Evidence condition",
      "question": "Were concurrent medication, activity and supervisory contact verified?",
      "needed": "Concurrent treatment, changes, actual exposure, measurement conditions and attribution",
      "role": "Required",
      "role_reason": "This condition connects Concurrent treatment, changes, actual exposure, measurement conditions and attribution with supervised office SBP, omnibus tests, specific comparisons, within-group changes, measurement settings, denominators, attrition, directness and harm boundaries.",
      "application_exception": "Preserve selected C and the note supporting the direction in small trials while specific adjusted effects remain unverified. Distinguish absent subclaim score/status/axes from parent C with 50 points. Omnibus tests, within-group changes and other measurement settings do not become new specific effects, CIs or independent replication. Create no new grades, safety certification or exercise, breathing, medication or treatment instructions.",
      "criterion": "Material for Concurrent treatment, changes, actual exposure, measurement conditions and attribution must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.",
      "basis": "Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.",
      "condition_origin": "Internally applied conditions preserved for the existing subclaim. They do not establish preregistration, official-tool certification or completed content review.",
      "proposed_research": "Material needed: Arm medication/changes, concurrent activity, adherence, measurement conditions, models, denominators and original effects are needed. Do not establish identical conditions or effects without medication. This records needed materials; no new research was executed.",
      "current_reports": [
        "R01",
        "R02",
        "R03"
      ],
      "existence": "Display information in the original parent stored summary is preserved. Public availability, acquisition and actual reading of detailed external material are separately unverified.",
      "acquired_read": "Stored summary read; external abstracts, full texts, registration, protocols, SAPs and support disclosures unread",
      "observation": "The original text records treated participants and supervised/home conditions. Medication types, doses, changes, baseline activity, premeasurement conditions, contact and actual exposure details are absent.",
      "condition_status": "Partly verified",
      "status_reason": "The selected claim, parent material and reports are distinguished and transferred from the stored summary. Detailed original material is unverified and review of existing content remains incomplete. This does not establish completed clinical review or certification.",
      "missingness": "Arm medication/changes, concurrent activity, adherence, measurement conditions, models, denominators and original effects are needed. Do not establish identical conditions or effects without medication.",
      "uncertainty": "External original material is unread and review of existing content remains incomplete. Original grades, scores, axes, historical verification and independence statements are not treated as new verdicts or certification.",
      "review_date": null,
      "reading_status": "Full text not read · Stored summary read",
      "additional_material": "Arm medication/changes, concurrent activity, adherence, measurement conditions, models, denominators and original effects are needed. Do not establish identical conditions or effects without medication."
    },
    {
      "item_id": "N19",
      "question_type": "Evidence condition",
      "question": "Were randomization, blinding, measurement and timing verified?",
      "needed": "Allocation, concealment, evaluators, standardized measurement, planning and missingness",
      "role": "Required",
      "role_reason": "This condition connects Allocation, concealment, evaluators, standardized measurement, planning and missingness with supervised office SBP, omnibus tests, specific comparisons, within-group changes, measurement settings, denominators, attrition, directness and harm boundaries.",
      "application_exception": "Preserve selected C and the note supporting the direction in small trials while specific adjusted effects remain unverified. Distinguish absent subclaim score/status/axes from parent C with 50 points. Omnibus tests, within-group changes and other measurement settings do not become new specific effects, CIs or independent replication. Create no new grades, safety certification or exercise, breathing, medication or treatment instructions.",
      "criterion": "Material for Allocation, concealment, evaluators, standardized measurement, planning and missingness must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.",
      "basis": "Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.",
      "condition_origin": "Internally applied conditions preserved for the existing subclaim. They do not establish preregistration, official-tool certification or completed content review.",
      "proposed_research": "Material needed: Original methods, measurement procedures, blinding, baseline adjustment/missingness, planned endpoints/comparisons/timing and analysis plans are needed. Create no official method-assessment pass or new grade. This records needed materials; no new research was executed.",
      "current_reports": [
        "R01",
        "R02",
        "R03"
      ],
      "existence": "Display information in the original parent stored summary is preserved. Public availability, acquisition and actual reading of detailed external material are separately unverified.",
      "acquired_read": "Stored summary read; external abstracts, full texts, registration, protocols, SAPs and support disclosures unread",
      "observation": "Original evidence labels randomized trials, but allocation, concealment, evaluators, standardized measurement, prospective planning, multiple time points and detailed attrition are absent from summaries. Preserve original B2 and small-sample/attrition limitations.",
      "condition_status": "Partly verified",
      "status_reason": "The selected claim, parent material and reports are distinguished and transferred from the stored summary. Detailed original material is unverified and review of existing content remains incomplete. This does not establish completed clinical review or certification.",
      "missingness": "Original methods, measurement procedures, blinding, baseline adjustment/missingness, planned endpoints/comparisons/timing and analysis plans are needed. Create no official method-assessment pass or new grade.",
      "uncertainty": "External original material is unread and review of existing content remains incomplete. Original grades, scores, axes, historical verification and independence statements are not treated as new verdicts or certification.",
      "review_date": null,
      "reading_status": "Full text not read · Stored summary read",
      "additional_material": "Original methods, measurement procedures, blinding, baseline adjustment/missingness, planned endpoints/comparisons/timing and analysis plans are needed. Create no official method-assessment pass or new grade."
    },
    {
      "item_id": "N20",
      "question_type": "Evidence condition",
      "question": "Are registration identifiers equivalent to reading original plans?",
      "needed": "Registration, paper linkage, changes, protocols, SAPs and planned endpoints",
      "role": "Required",
      "role_reason": "This condition connects Registration, paper linkage, changes, protocols, SAPs and planned endpoints with supervised office SBP, omnibus tests, specific comparisons, within-group changes, measurement settings, denominators, attrition, directness and harm boundaries.",
      "application_exception": "Preserve selected C and the note supporting the direction in small trials while specific adjusted effects remain unverified. Distinguish absent subclaim score/status/axes from parent C with 50 points. Omnibus tests, within-group changes and other measurement settings do not become new specific effects, CIs or independent replication. Create no new grades, safety certification or exercise, breathing, medication or treatment instructions.",
      "criterion": "Material for Registration, paper linkage, changes, protocols, SAPs and planned endpoints must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.",
      "basis": "Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.",
      "condition_origin": "Internally applied conditions preserved for the existing subclaim. They do not establish preregistration, official-tool certification or completed content review.",
      "proposed_research": "Material needed: Original registration, changes, paper linkage, protocols/SAPs, planned endpoints, arm comparisons and denominators are needed. Identifiers, URLs and PMCID alone do not establish reading or prospective verification. This records needed materials; no new research was executed.",
      "current_reports": [
        "R01",
        "R02",
        "R03"
      ],
      "existence": "Display information in the original parent stored summary is preserved. Public availability, acquisition and actual reading of detailed external material are separately unverified.",
      "acquired_read": "Stored summary read; external abstracts, full texts, registration, protocols, SAPs and support disclosures unread",
      "observation": "Farah NCT02348138 and Palmeira NCT03216317 are original identifiers; registration for the 2024 report is unverified. PMCID is preserved in the bibliography; external registration, plans, full texts and prospective-status comparisons were unread this run.",
      "condition_status": "Partly verified",
      "status_reason": "The selected claim, parent material and reports are distinguished and transferred from the stored summary. Detailed original material is unverified and review of existing content remains incomplete. This does not establish completed clinical review or certification.",
      "missingness": "Original registration, changes, paper linkage, protocols/SAPs, planned endpoints, arm comparisons and denominators are needed. Identifiers, URLs and PMCID alone do not establish reading or prospective verification.",
      "uncertainty": "External original material is unread and review of existing content remains incomplete. Original grades, scores, axes, historical verification and independence statements are not treated as new verdicts or certification.",
      "review_date": null,
      "reading_status": "Full text not read · Stored summary read",
      "additional_material": "Original registration, changes, paper linkage, protocols/SAPs, planned endpoints, arm comparisons and denominators are needed. Identifiers, URLs and PMCID alone do not establish reading or prospective verification."
    },
    {
      "item_id": "N21",
      "question_type": "Evidence condition",
      "question": "What were funding, products, employee authors and design/analysis roles?",
      "needed": "Financial/device/product support, author affiliations and design/analysis/publication control",
      "role": "Required",
      "role_reason": "This condition connects Financial/device/product support, author affiliations and design/analysis/publication control with supervised office SBP, omnibus tests, specific comparisons, within-group changes, measurement settings, denominators, attrition, directness and harm boundaries.",
      "application_exception": "Preserve selected C and the note supporting the direction in small trials while specific adjusted effects remain unverified. Distinguish absent subclaim score/status/axes from parent C with 50 points. Omnibus tests, within-group changes and other measurement settings do not become new specific effects, CIs or independent replication. Create no new grades, safety certification or exercise, breathing, medication or treatment instructions.",
      "criterion": "Material for Financial/device/product support, author affiliations and design/analysis/publication control must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.",
      "basis": "Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.",
      "condition_origin": "Internally applied conditions preserved for the existing subclaim. They do not establish preregistration, official-tool certification or completed content review.",
      "proposed_research": "Material needed: Disclosures of financial/device/product support, company/author affiliations, design/analysis/publication roles and institutional, recruitment and report relationships are unread. Do not fill in no support or involvement. This records needed materials; no new research was executed.",
      "current_reports": [
        "R01",
        "R02",
        "R03"
      ],
      "existence": "Display information in the original parent stored summary is preserved. Public availability, acquisition and actual reading of detailed external material are separately unverified.",
      "acquired_read": "Stored summary read; external abstracts, full texts, registration, protocols, SAPs and support disclosures unread",
      "observation": "Preserve Farah public/academic support, Palmeira public primary-care support and the 2024 report's academic support. Public/academic wording or parent I2 does not become new certification of overall independence.",
      "condition_status": "Partly verified",
      "status_reason": "The selected claim, parent material and reports are distinguished and transferred from the stored summary. Detailed original material is unverified and review of existing content remains incomplete. This does not establish completed clinical review or certification.",
      "missingness": "Disclosures of financial/device/product support, company/author affiliations, design/analysis/publication roles and institutional, recruitment and report relationships are unread. Do not fill in no support or involvement.",
      "uncertainty": "External original material is unread and review of existing content remains incomplete. Original grades, scores, axes, historical verification and independence statements are not treated as new verdicts or certification.",
      "review_date": null,
      "reading_status": "Full text not read · Stored summary read",
      "additional_material": "Disclosures of financial/device/product support, company/author affiliations, design/analysis/publication roles and institutional, recruitment and report relationships are unread. Do not fill in no support or involvement."
    },
    {
      "item_id": "N22",
      "question_type": "Evidence condition",
      "question": "Were pain, exercise pressure and vulnerable-group harms verified?",
      "needed": "Events, affected people, arm denominators, exposure, collection, stopping and follow-up",
      "role": "Supplementary",
      "role_reason": "This condition connects Events, affected people, arm denominators, exposure, collection, stopping and follow-up with supervised office SBP, omnibus tests, specific comparisons, within-group changes, measurement settings, denominators, attrition, directness and harm boundaries.",
      "application_exception": "Preserve selected C and the note supporting the direction in small trials while specific adjusted effects remain unverified. Distinguish absent subclaim score/status/axes from parent C with 50 points. Omnibus tests, within-group changes and other measurement settings do not become new specific effects, CIs or independent replication. Create no new grades, safety certification or exercise, breathing, medication or treatment instructions.",
      "criterion": "Material for Events, affected people, arm denominators, exposure, collection, stopping and follow-up must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.",
      "basis": "Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.",
      "condition_origin": "Internally applied conditions preserved for the existing subclaim. They do not establish preregistration, official-tool certification or completed content review.",
      "proposed_research": "Material needed: Harm collection, severity/timing, events/affected people, denominators, actual exposure, stopping, medication/vulnerable groups and long-term data are needed. Null ambulatory pressure does not become no harm or safety certification. This records needed materials; no new research was executed.",
      "current_reports": [
        "R01",
        "R02",
        "R03"
      ],
      "existence": "Display information in the original parent stored summary is preserved. Public availability, acquisition and actual reading of detailed external material are separately unverified.",
      "acquired_read": "Stored summary read; external abstracts, full texts, registration, protocols, SAPs and support disclosures unread",
      "observation": "Original safety text records hand/arm pain, pressure rises during breath-holding/Valsalva and uncontrolled-hypertension/cardiovascular-disease boundaries. Trial-specific harm events, exposure, denominators and collection are absent from summaries.",
      "condition_status": "Partly verified",
      "status_reason": "The selected claim, parent material and reports are distinguished and transferred from the stored summary. Detailed original material is unverified and review of existing content remains incomplete. This does not establish completed clinical review or certification.",
      "missingness": "Harm collection, severity/timing, events/affected people, denominators, actual exposure, stopping, medication/vulnerable groups and long-term data are needed. Null ambulatory pressure does not become no harm or safety certification.",
      "uncertainty": "External original material is unread and review of existing content remains incomplete. Original grades, scores, axes, historical verification and independence statements are not treated as new verdicts or certification.",
      "review_date": null,
      "reading_status": "Full text not read · Stored summary read",
      "additional_material": "Harm collection, severity/timing, events/affected people, denominators, actual exposure, stopping, medication/vulnerable groups and long-term data are needed. Null ambulatory pressure does not become no harm or safety certification."
    },
    {
      "item_id": "N23",
      "question_type": "Evidence condition",
      "question": "Are subclaim grades the same as parent scores and axes?",
      "needed": "Absent subclaim score/status/axes versus the parent verdict",
      "role": "Required",
      "role_reason": "This condition connects Absent subclaim score/status/axes versus the parent verdict with supervised office SBP, omnibus tests, specific comparisons, within-group changes, measurement settings, denominators, attrition, directness and harm boundaries.",
      "application_exception": "Preserve selected C and the note supporting the direction in small trials while specific adjusted effects remain unverified. Distinguish absent subclaim score/status/axes from parent C with 50 points. Omnibus tests, within-group changes and other measurement settings do not become new specific effects, CIs or independent replication. Create no new grades, safety certification or exercise, breathing, medication or treatment instructions.",
      "criterion": "Material for Absent subclaim score/status/axes versus the parent verdict must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.",
      "basis": "Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.",
      "condition_origin": "Internally applied conditions preserved for the existing subclaim. They do not establish preregistration, official-tool certification or completed content review.",
      "proposed_research": "Material needed: Do not fill subclaims with parent scores/axes or turn unrecorded precision into default values, new scores or independence certification. Distinguish parent/subclaim application boundaries. This records needed materials; no new research was executed.",
      "current_reports": [
        "R01",
        "R02",
        "R03"
      ],
      "existence": "Display information in the original parent stored summary is preserved. Public availability, acquisition and actual reading of detailed external material are separately unverified.",
      "acquired_read": "Stored summary read; external abstracts, full texts, registration, protocols, SAPs and support disclosures unread",
      "observation": "Supervised office subclaim C and ambulatory subclaim D have no individual score, status or axes. Preserve parent C with 50 points, caution, B/S/R1/I2/EX/B2 and unrecorded precision as parent context.",
      "condition_status": "Partly verified",
      "status_reason": "The selected claim, parent material and reports are distinguished and transferred from the stored summary. Detailed original material is unverified and review of existing content remains incomplete. This does not establish completed clinical review or certification.",
      "missingness": "Do not fill subclaims with parent scores/axes or turn unrecorded precision into default values, new scores or independence certification. Distinguish parent/subclaim application boundaries.",
      "uncertainty": "External original material is unread and review of existing content remains incomplete. Original grades, scores, axes, historical verification and independence statements are not treated as new verdicts or certification.",
      "review_date": null,
      "reading_status": "Full text not read · Stored summary read",
      "additional_material": "Do not fill subclaims with parent scores/axes or turn unrecorded precision into default values, new scores or independence certification. Distinguish parent/subclaim application boundaries."
    },
    {
      "item_id": "N24",
      "question_type": "Evidence condition",
      "question": "How are representative information and both languages preserved?",
      "needed": "Report-specific populations, supervision, measurement settings, outcomes, timing and denominators",
      "role": "Required",
      "role_reason": "This condition connects Report-specific populations, supervision, measurement settings, outcomes, timing and denominators with supervised office SBP, omnibus tests, specific comparisons, within-group changes, measurement settings, denominators, attrition, directness and harm boundaries.",
      "application_exception": "Preserve selected C and the note supporting the direction in small trials while specific adjusted effects remain unverified. Distinguish absent subclaim score/status/axes from parent C with 50 points. Omnibus tests, within-group changes and other measurement settings do not become new specific effects, CIs or independent replication. Create no new grades, safety certification or exercise, breathing, medication or treatment instructions.",
      "criterion": "Material for Report-specific populations, supervision, measurement settings, outcomes, timing and denominators must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.",
      "basis": "Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.",
      "condition_origin": "Internally applied conditions preserved for the existing subclaim. They do not establish preregistration, official-tool certification or completed content review.",
      "proposed_research": "Material needed: Report-specific delivery, supervision, measurement settings, endpoints, timing, denominators and original English comparison materials are needed. No external English comparison or correction review was performed this run. This records needed materials; no new research was executed.",
      "current_reports": [
        "R01",
        "R02",
        "R03"
      ],
      "existence": "Display information in the original parent stored summary is preserved. Public availability, acquisition and actual reading of detailed external material are separately unverified.",
      "acquired_read": "Stored summary read; external abstracts, full texts, registration, protocols, SAPs and support disclosures unread",
      "observation": "Preserve complete bilingual texts and representative information. Representative 72 participants, 12 weeks, no exercise and office/central/ambulatory labels do not automatically apply to 63 or 84 participants, all day/night/home outcomes or each arm.",
      "condition_status": "Partly verified",
      "status_reason": "The selected claim, parent material and reports are distinguished and transferred from the stored summary. Detailed original material is unverified and review of existing content remains incomplete. This does not establish completed clinical review or certification.",
      "missingness": "Report-specific delivery, supervision, measurement settings, endpoints, timing, denominators and original English comparison materials are needed. No external English comparison or correction review was performed this run.",
      "uncertainty": "External original material is unread and review of existing content remains incomplete. Original grades, scores, axes, historical verification and independence statements are not treated as new verdicts or certification.",
      "review_date": null,
      "reading_status": "Full text not read · Stored summary read",
      "additional_material": "Report-specific delivery, supervision, measurement settings, endpoints, timing, denominators and original English comparison materials are needed. No external English comparison or correction review was performed this run."
    },
    {
      "item_id": "N25",
      "question_type": "Evidence condition",
      "question": "How are actual reading and report/material counts distinguished?",
      "needed": "Stored summaries, external reading and trial/report/cohort relationships",
      "role": "Required",
      "role_reason": "This condition connects Stored summaries, external reading and trial/report/cohort relationships with supervised office SBP, omnibus tests, specific comparisons, within-group changes, measurement settings, denominators, attrition, directness and harm boundaries.",
      "application_exception": "Preserve selected C and the note supporting the direction in small trials while specific adjusted effects remain unverified. Distinguish absent subclaim score/status/axes from parent C with 50 points. Omnibus tests, within-group changes and other measurement settings do not become new specific effects, CIs or independent replication. Create no new grades, safety certification or exercise, breathing, medication or treatment instructions.",
      "criterion": "Material for Stored summaries, external reading and trial/report/cohort relationships must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.",
      "basis": "Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.",
      "condition_origin": "Internally applied conditions preserved for the existing subclaim. They do not establish preregistration, official-tool certification or completed content review.",
      "proposed_research": "Material needed: Original-material acquisition, actual reading and trial/report/cohort relationships are unverified. URLs/identifiers alone do not establish completed reading or unique-trial/participant totals. This records needed materials; no new research was executed.",
      "current_reports": [
        "R01",
        "R02",
        "R03"
      ],
      "existence": "Display information in the original parent stored summary is preserved. Public availability, acquisition and actual reading of detailed external material are separately unverified.",
      "acquired_read": "Stored summary read; external abstracts, full texts, registration, protocols, SAPs and support disclosures unread",
      "observation": "The complete parent JSON was read for production. Historical verification, separation and cross-checks remain historical records; external materials are unread. Report/material counts do not count acquired papers, independent trials, participants or quality scores.",
      "condition_status": "Partly verified",
      "status_reason": "The selected claim, parent material and reports are distinguished and transferred from the stored summary. Detailed original material is unverified and review of existing content remains incomplete. This does not establish completed clinical review or certification.",
      "missingness": "Original-material acquisition, actual reading and trial/report/cohort relationships are unverified. URLs/identifiers alone do not establish completed reading or unique-trial/participant totals.",
      "uncertainty": "External original material is unread and review of existing content remains incomplete. Original grades, scores, axes, historical verification and independence statements are not treated as new verdicts or certification.",
      "review_date": null,
      "reading_status": "Full text not read · Stored summary read",
      "additional_material": "Original-material acquisition, actual reading and trial/report/cohort relationships are unverified. URLs/identifiers alone do not establish completed reading or unique-trial/participant totals."
    },
    {
      "item_id": "N26",
      "question_type": "Evidence condition",
      "question": "What are the evidence date and correction history?",
      "needed": "Original date, empty correction/deliberation records, production timing and original URLs",
      "role": "Required",
      "role_reason": "This condition connects Original date, empty correction/deliberation records, production timing and original URLs with supervised office SBP, omnibus tests, specific comparisons, within-group changes, measurement settings, denominators, attrition, directness and harm boundaries.",
      "application_exception": "Preserve selected C and the note supporting the direction in small trials while specific adjusted effects remain unverified. Distinguish absent subclaim score/status/axes from parent C with 50 points. Omnibus tests, within-group changes and other measurement settings do not become new specific effects, CIs or independent replication. Create no new grades, safety certification or exercise, breathing, medication or treatment instructions.",
      "criterion": "Material for Original date, empty correction/deliberation records, production timing and original URLs must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.",
      "basis": "Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.",
      "condition_origin": "Internally applied conditions preserved for the existing subclaim. They do not establish preregistration, official-tool certification or completed content review.",
      "proposed_research": "Material needed: When originals/corrections are acquired, preserve and link complete texts, events, versions and reasons. No original-verdict change or external lookup was performed this run. This records needed materials; no new research was executed.",
      "current_reports": [
        "R01",
        "R02",
        "R03"
      ],
      "existence": "Display information in the original parent stored summary is preserved. Public availability, acquisition and actual reading of detailed external material are separately unverified.",
      "acquired_read": "Stored summary read; external abstracts, full texts, registration, protocols, SAPs and support disclosures unread",
      "observation": "Preserve original evidence date 2026-09-07 and empty correction/deliberation records. Figure/table inconsistencies do not justify inventing corrections or turning production dates into evidence-verification dates.",
      "condition_status": "Partly verified",
      "status_reason": "The selected claim, parent material and reports are distinguished and transferred from the stored summary. Detailed original material is unverified and review of existing content remains incomplete. This does not establish completed clinical review or certification.",
      "missingness": "When originals/corrections are acquired, preserve and link complete texts, events, versions and reasons. No original-verdict change or external lookup was performed this run.",
      "uncertainty": "External original material is unread and review of existing content remains incomplete. Original grades, scores, axes, historical verification and independence statements are not treated as new verdicts or certification.",
      "review_date": null,
      "reading_status": "Full text not read · Stored summary read",
      "additional_material": "When originals/corrections are acquired, preserve and link complete texts, events, versions and reasons. No original-verdict change or external lookup was performed this run."
    },
    {
      "item_id": "N27",
      "question_type": "Evidence condition",
      "question": "How will new materials and changed questions be updated?",
      "needed": "Evidence updates, criteria revisions and original-verdict changes",
      "role": "Required",
      "role_reason": "This condition connects Evidence updates, criteria revisions and original-verdict changes with supervised office SBP, omnibus tests, specific comparisons, within-group changes, measurement settings, denominators, attrition, directness and harm boundaries.",
      "application_exception": "Preserve selected C and the note supporting the direction in small trials while specific adjusted effects remain unverified. Distinguish absent subclaim score/status/axes from parent C with 50 points. Omnibus tests, within-group changes and other measurement settings do not become new specific effects, CIs or independent replication. Create no new grades, safety certification or exercise, breathing, medication or treatment instructions.",
      "criterion": "Material for Evidence updates, criteria revisions and original-verdict changes must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.",
      "basis": "Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.",
      "condition_origin": "Internally applied conditions preserved for the existing subclaim. They do not establish preregistration, official-tool certification or completed content review.",
      "proposed_research": "Material needed: Updates must retain complete texts, criteria versions, events and reasons. Do not invent clinical calculations, effects/CIs, independence certification, exercise methods, pressure-medication reduction/replacement or treatment instructions. This records needed materials; no new research was executed.",
      "current_reports": [
        "R01",
        "R02",
        "R03"
      ],
      "existence": "Display information in the original parent stored summary is preserved. Public availability, acquisition and actual reading of detailed external material are separately unverified.",
      "acquired_read": "Stored summary read; external abstracts, full texts, registration, protocols, SAPs and support disclosures unread",
      "observation": "Preserve original materials, conditions and observations. New materials are linked to supervision/controls, measurement settings, denominators, endpoints/timing/day-night, related reports and subclaim scope; no new lookup or reassessment occurred this run.",
      "condition_status": "Partly verified",
      "status_reason": "The selected claim, parent material and reports are distinguished and transferred from the stored summary. Detailed original material is unverified and review of existing content remains incomplete. This does not establish completed clinical review or certification.",
      "missingness": "Updates must retain complete texts, criteria versions, events and reasons. Do not invent clinical calculations, effects/CIs, independence certification, exercise methods, pressure-medication reduction/replacement or treatment instructions.",
      "uncertainty": "External original material is unread and review of existing content remains incomplete. Original grades, scores, axes, historical verification and independence statements are not treated as new verdicts or certification.",
      "review_date": null,
      "reading_status": "Full text not read · Stored summary read",
      "additional_material": "Updates must retain complete texts, criteria versions, events and reasons. Do not invent clinical calculations, effects/CIs, independence certification, exercise methods, pressure-medication reduction/replacement or treatment instructions."
    }
  ],
  "reports": [
    {
      "report_id": "R01",
      "title": "Farah BQ, et al. Supervised, but Not Home-Based, Isometric Training Improves Brachial and Central Blood Pressure in Medicated Hypertensive Patients. Front Physiol. 2018;9:961. PMID: 30083107. PMCID: PMC6065303. DOI: 10.3389/fphys.2018.00961.",
      "url": "https://pubmed.ncbi.nlm.nih.gov/30083107/",
      "report_type": "Three-arm supervised, home, and no-exercise randomized trial",
      "existence": "Report linked in the original parent stored summary evidence/citation lists. External public availability, access and current acquisition of the original are unverified.",
      "acquired_read": "Stored summary read; external abstracts, full texts, registration, protocols, SAPs and support disclosures unread",
      "study_family": "Original report R01; unique counts and independent replication unverified",
      "independent_replication": "Supervised office SBP and the separate ambulatory-pressure question share Farah, Palmeira and the 2024 home-training reports. Report/cohort relationships and unique-trial/participant totals are unverified. Multiple sheets, measures and report participants are not counted as new independent trials or participant totals.",
      "observed_result": "Office SBP P=.041 and DBP P=.049; ambulatory SBP P=.650 and DBP P=.340",
      "result_level": "Medicated hypertension, 72 randomized, 12 weeks and supervised/home/no-exercise 3-arm conditions. Office SBP P=.041 and DBP P=.049 are omnibus group-by-time tests; specific adjusted effects/95% CIs are unverified. Preserve null 24-hour SBP P=.650/DBP P=.340, figure/table arm-label inconsistencies and missing exact arm denominators.",
      "source_evidence_date": "2026-09-07",
      "materials": [
        {
          "material_type": "Stored existing review summary",
          "public_status": "Preserved copy of the complete parent-verdict stored summary",
          "access_status": "Stored summary",
          "acquired": true,
          "actually_read": "Summary read",
          "as_of": "2026-09-07",
          "qualification": "Preserve original PubMed URL, PMID 30083107, PMCID PMC6065303, DOI 10.3389/fphys.2018.00961 and registration wording NCT02348138. External full text, registration and protocols/SAPs are unread; infer no new URLs, prospective status, registration changes or resolution of inconsistencies."
        },
        {
          "material_type": "External abstract",
          "public_status": "Original bibliographic link or needed material; external public availability/access status unverified",
          "access_status": "Unread; access not attempted",
          "acquired": false,
          "actually_read": "Not read",
          "as_of": null,
          "qualification": "Preserve original PubMed URL, PMID 30083107, PMCID PMC6065303, DOI 10.3389/fphys.2018.00961 and registration wording NCT02348138. External full text, registration and protocols/SAPs are unread; infer no new URLs, prospective status, registration changes or resolution of inconsistencies."
        },
        {
          "material_type": "External full text",
          "public_status": "Original bibliographic link or needed material; external public availability/access status unverified",
          "access_status": "Unread; access not attempted",
          "acquired": false,
          "actually_read": "Not read",
          "as_of": null,
          "qualification": "Preserve original PubMed URL, PMID 30083107, PMCID PMC6065303, DOI 10.3389/fphys.2018.00961 and registration wording NCT02348138. External full text, registration and protocols/SAPs are unread; infer no new URLs, prospective status, registration changes or resolution of inconsistencies."
        },
        {
          "material_type": "Registration material",
          "public_status": "Original bibliographic link or needed material; external public availability/access status unverified",
          "access_status": "Unread; access not attempted",
          "acquired": false,
          "actually_read": "Not read",
          "as_of": null,
          "qualification": "Preserve original PubMed URL, PMID 30083107, PMCID PMC6065303, DOI 10.3389/fphys.2018.00961 and registration wording NCT02348138. External full text, registration and protocols/SAPs are unread; infer no new URLs, prospective status, registration changes or resolution of inconsistencies."
        },
        {
          "material_type": "Protocol and analysis plan",
          "public_status": "Original bibliographic link or needed material; external public availability/access status unverified",
          "access_status": "Unread; access not attempted",
          "acquired": false,
          "actually_read": "Not read",
          "as_of": null,
          "qualification": "Preserve original PubMed URL, PMID 30083107, PMCID PMC6065303, DOI 10.3389/fphys.2018.00961 and registration wording NCT02348138. External full text, registration and protocols/SAPs are unread; infer no new URLs, prospective status, registration changes or resolution of inconsistencies."
        }
      ],
      "links": [
        {
          "label": "PubMed",
          "url": "https://pubmed.ncbi.nlm.nih.gov/30083107/"
        }
      ]
    },
    {
      "report_id": "R02",
      "title": "Palmeira AC, et al. Effects of isometric handgrip training on blood pressure among hypertensive patients seen within public primary healthcare: a randomized controlled trial. Sao Paulo Med J. 2021;139:648-656. PMID: 34787298. PMCID: PMC9634841. DOI: 10.1590/1516-3180.2020.0796.R1.22042021.",
      "url": "https://pubmed.ncbi.nlm.nih.gov/34787298/",
      "report_type": "Twelve-week randomized controlled trial",
      "existence": "Report linked in the original parent stored summary evidence/citation lists. External public availability, access and current acquisition of the original are unverified.",
      "acquired_read": "Stored summary read; external abstracts, full texts, registration, protocols, SAPs and support disclosures unread",
      "study_family": "Original report R02; unique counts and independent replication unverified",
      "independent_replication": "Supervised office SBP and the separate ambulatory-pressure question share Farah, Palmeira and the 2024 home-training reports. Report/cohort relationships and unique-trial/participant totals are unverified. Multiple sheets, measures and report participants are not counted as new independent trials or participant totals.",
      "observed_result": "Office SBP interaction positive; DBP and ambulatory pressure null",
      "result_level": "In a 63-participant, 12-week randomized primary-care hypertension trial, preserve positive office-SBP interaction and null DBP/ambulatory pressure. Exact completion/analysis counts amid large attrition, arm denominators, original effects/CIs, P and models are unverified; do not copy P from the key trial.",
      "source_evidence_date": "2026-09-07",
      "materials": [
        {
          "material_type": "Stored existing review summary",
          "public_status": "Preserved copy of the complete parent-verdict stored summary",
          "access_status": "Stored summary",
          "acquired": true,
          "actually_read": "Summary read",
          "as_of": "2026-09-07",
          "qualification": "Preserve original PubMed URL, PMID 34787298, PMCID PMC9634841, DOI 10.1590/1516-3180.2020.0796.R1.22042021 and registration wording NCT03216317. External full text, registration and protocols/SAPs are unread; identifiers/PMCID alone do not establish prospective status, reading or verified analysis plans."
        },
        {
          "material_type": "External abstract",
          "public_status": "Original bibliographic link or needed material; external public availability/access status unverified",
          "access_status": "Unread; access not attempted",
          "acquired": false,
          "actually_read": "Not read",
          "as_of": null,
          "qualification": "Preserve original PubMed URL, PMID 34787298, PMCID PMC9634841, DOI 10.1590/1516-3180.2020.0796.R1.22042021 and registration wording NCT03216317. External full text, registration and protocols/SAPs are unread; identifiers/PMCID alone do not establish prospective status, reading or verified analysis plans."
        },
        {
          "material_type": "External full text",
          "public_status": "Original bibliographic link or needed material; external public availability/access status unverified",
          "access_status": "Unread; access not attempted",
          "acquired": false,
          "actually_read": "Not read",
          "as_of": null,
          "qualification": "Preserve original PubMed URL, PMID 34787298, PMCID PMC9634841, DOI 10.1590/1516-3180.2020.0796.R1.22042021 and registration wording NCT03216317. External full text, registration and protocols/SAPs are unread; identifiers/PMCID alone do not establish prospective status, reading or verified analysis plans."
        },
        {
          "material_type": "Registration material",
          "public_status": "Original bibliographic link or needed material; external public availability/access status unverified",
          "access_status": "Unread; access not attempted",
          "acquired": false,
          "actually_read": "Not read",
          "as_of": null,
          "qualification": "Preserve original PubMed URL, PMID 34787298, PMCID PMC9634841, DOI 10.1590/1516-3180.2020.0796.R1.22042021 and registration wording NCT03216317. External full text, registration and protocols/SAPs are unread; identifiers/PMCID alone do not establish prospective status, reading or verified analysis plans."
        },
        {
          "material_type": "Protocol and analysis plan",
          "public_status": "Original bibliographic link or needed material; external public availability/access status unverified",
          "access_status": "Unread; access not attempted",
          "acquired": false,
          "actually_read": "Not read",
          "as_of": null,
          "qualification": "Preserve original PubMed URL, PMID 34787298, PMCID PMC9634841, DOI 10.1590/1516-3180.2020.0796.R1.22042021 and registration wording NCT03216317. External full text, registration and protocols/SAPs are unread; identifiers/PMCID alone do not establish prospective status, reading or verified analysis plans."
        }
      ],
      "links": [
        {
          "label": "PubMed",
          "url": "https://pubmed.ncbi.nlm.nih.gov/34787298/"
        }
      ]
    },
    {
      "report_id": "R03",
      "title": "Home-based isometric handgrip training in older adults with hypertension. J Am Geriatr Soc. 2024. PMID: 39392028. DOI: 10.1111/jgs.19213.",
      "url": "https://pubmed.ncbi.nlm.nih.gov/39392028/",
      "report_type": "Randomized home-training trial in older adults",
      "existence": "Report linked in the original parent stored summary evidence/citation lists. External public availability, access and current acquisition of the original are unverified.",
      "acquired_read": "Stored summary read; external abstracts, full texts, registration, protocols, SAPs and support disclosures unread",
      "study_family": "Original report R03; unique counts and independent replication unverified",
      "independent_replication": "Supervised office SBP and the separate ambulatory-pressure question share Farah, Palmeira and the 2024 home-training reports. Report/cohort relationships and unique-trial/participant totals are unverified. Multiple sheets, measures and report participants are not counted as new independent trials or participant totals.",
      "observed_result": "24-hour ambulatory and between-group office pressure were null",
      "result_level": "Preserve null 24-hour and between-group office pressure in the 2024 report of 84 older home-training participants. This does not replicate supervised effects under the same conditions; exact duration, comparator, effects/CIs, P and arm denominators are unverified.",
      "source_evidence_date": "2026-09-07",
      "materials": [
        {
          "material_type": "Stored existing review summary",
          "public_status": "Preserved copy of the complete parent-verdict stored summary",
          "access_status": "Stored summary",
          "acquired": true,
          "actually_read": "Summary read",
          "as_of": "2026-09-07",
          "qualification": "Preserve original PubMed URL, PMID 39392028 and DOI 10.1111/jgs.19213. PMCID and a separate registration annotation are unrecorded; original registration wording is unverified. Do not infer no registration, new identifiers/URLs, prospective status or original-text reading."
        },
        {
          "material_type": "External abstract",
          "public_status": "Original bibliographic link or needed material; external public availability/access status unverified",
          "access_status": "Unread; access not attempted",
          "acquired": false,
          "actually_read": "Not read",
          "as_of": null,
          "qualification": "Preserve original PubMed URL, PMID 39392028 and DOI 10.1111/jgs.19213. PMCID and a separate registration annotation are unrecorded; original registration wording is unverified. Do not infer no registration, new identifiers/URLs, prospective status or original-text reading."
        },
        {
          "material_type": "External full text",
          "public_status": "Original bibliographic link or needed material; external public availability/access status unverified",
          "access_status": "Unread; access not attempted",
          "acquired": false,
          "actually_read": "Not read",
          "as_of": null,
          "qualification": "Preserve original PubMed URL, PMID 39392028 and DOI 10.1111/jgs.19213. PMCID and a separate registration annotation are unrecorded; original registration wording is unverified. Do not infer no registration, new identifiers/URLs, prospective status or original-text reading."
        },
        {
          "material_type": "Registration material",
          "public_status": "Original bibliographic link or needed material; external public availability/access status unverified",
          "access_status": "Unread; access not attempted",
          "acquired": false,
          "actually_read": "Not read",
          "as_of": null,
          "qualification": "Preserve original PubMed URL, PMID 39392028 and DOI 10.1111/jgs.19213. PMCID and a separate registration annotation are unrecorded; original registration wording is unverified. Do not infer no registration, new identifiers/URLs, prospective status or original-text reading."
        },
        {
          "material_type": "Protocol and analysis plan",
          "public_status": "Original bibliographic link or needed material; external public availability/access status unverified",
          "access_status": "Unread; access not attempted",
          "acquired": false,
          "actually_read": "Not read",
          "as_of": null,
          "qualification": "Preserve original PubMed URL, PMID 39392028 and DOI 10.1111/jgs.19213. PMCID and a separate registration annotation are unrecorded; original registration wording is unverified. Do not infer no registration, new identifiers/URLs, prospective status or original-text reading."
        }
      ],
      "links": [
        {
          "label": "PubMed",
          "url": "https://pubmed.ncbi.nlm.nih.gov/39392028/"
        }
      ]
    }
  ],
  "method_sources": [
    {
      "id": "M03",
      "version": "Cochrane Handbook 6.5 (2024), chapter updated 2023-08",
      "url": "https://www.cochrane.org/authors/handbooks-and-manuals/handbook/current/chapter-03",
      "section": "§3.1, §3.2.1–3.2.3, MECIR C5/C7/C13",
      "official_principle": "Clearly record the question, eligibility conditions and reasons for changes, and distinguish variations in interventions.",
      "review_level": "Existing methodological links were reused for production. External originals were not reread and methodological content was not reassessed."
    },
    {
      "id": "M04",
      "version": "Cochrane Handbook 6.5.1 (2025), chapter updated 2025-03",
      "url": "https://www.cochrane.org/authors/handbooks-and-manuals/handbook/current/chapter-04",
      "section": "§4.5, §4.6.1–4.6.3, MECIR C42",
      "official_principle": "Distinguish studies from reports and link them; do not omit a study solely because results are unreported.",
      "review_level": "Existing methodological links were reused for production. External originals were not reread and methodological content was not reassessed."
    },
    {
      "id": "M08",
      "version": "Cochrane Handbook 6.5 (2024), chapter updated 2019-10",
      "url": "https://www.cochrane.org/authors/handbooks-and-manuals/handbook/current/chapter-08",
      "section": "§8.1–8.2.3, Table 8.2.a",
      "official_principle": "Define the outcome and effect of interest, then examine randomization, deviations, missing data, measurement and selective reporting.",
      "review_level": "Existing methodological links were reused for production. External originals were not reread and methodological content was not reassessed."
    },
    {
      "id": "M15",
      "version": "Cochrane Handbook 6.5 (2024), chapter updated 2023-08",
      "url": "https://www.cochrane.org/authors/handbooks-and-manuals/handbook/current/chapter-15",
      "section": "§15.2.4, §15.3.1–15.3.3",
      "official_principle": "Distinguish effect estimates, intervals, importance and applicability. Sample size alone does not determine precision.",
      "review_level": "Existing methodological links were reused for production. External originals were not reread and methodological content was not reassessed."
    },
    {
      "id": "M19",
      "version": "Cochrane Handbook 6.5 (2024), chapter updated 2019-10",
      "url": "https://www.cochrane.org/authors/handbooks-and-manuals/handbook/current/chapter-19",
      "section": "§19.1.2, §19.2.1–19.2.4",
      "official_principle": "Harm questions may require different designs, populations and follow-up from efficacy questions. Case reports do not establish incidence rates.",
      "review_level": "Existing methodological links were reused for production. External originals were not reread and methodological content was not reassessed."
    }
  ],
  "status_dictionary": {
    "Partly verified": "Some information is present in the stored source, with detailed original materials still unverified; this does not mean review passed or clinical efficacy certified",
    "Unverified": "Detailed materials for the selected condition could not be established within the stored scope; this does not mean zero effect, zero studies or safety",
    "Review incomplete": "Awaiting user review",
    "Met": "Use only within the relevant condition's scope after user review; no automatic display in this preparation",
    "Not reported": "Distinguish only within materials actually read; do not turn unread external materials into unreported findings",
    "Inaccessible": "Not applied during this preparation because actual access was not tested",
    "Not applicable": "Use with a reason for non-applicability based on an explicit question boundary",
    "Conflicting data": "Judge after actual material comparison; review was not performed during this preparation",
    "Insufficient evidence for the conditions": "Do not use as a clinical grade encompassing currently unread materials"
  },
  "study_overlap": {
    "state": "Unverified",
    "unique_trial_count": null,
    "unique_participant_count": null,
    "reason": "Supervised office SBP and the separate ambulatory-pressure question share Farah, Palmeira and the 2024 home-training reports. Report/cohort relationships and unique-trial/participant totals are unverified. Multiple sheets, measures and report participants are not counted as new independent trials or participant totals."
  },
  "history": [
    {
      "date": "2026-10-18",
      "kind": "Separation of public-facing pages and materials",
      "view_version": "1.0",
      "change": "Public pages and materials were prepared from the existing 27 items. No new clinical search, verification-status change or scoring was performed."
    }
  ],
  "language": "en",
  "translation_date": "2026-10-18"
}