{
  "schema_version": "chamgap-public-criteria-1.0",
  "title": "30% MVC handgrip × supervised office SBP: evidence checklist",
  "language": "en",
  "translation_date": "2026-10-18",
  "criteria_version": "1.0",
  "criteria_date": "2026-10-06",
  "condition_origin": "Chamgap's own application conditions",
  "method_sources": [
    {
      "id": "M03",
      "version": "Cochrane Handbook 6.5 (2024), chapter updated 2023-08",
      "url": "https://www.cochrane.org/authors/handbooks-and-manuals/handbook/current/chapter-03",
      "section": "§3.1, §3.2.1–3.2.3, MECIR C5/C7/C13",
      "official_principle": "Clearly record the question, eligibility conditions and reasons for changes, and distinguish variations in interventions.",
      "review_level": "Existing methodological links were reused for production. External originals were not reread and methodological content was not reassessed."
    },
    {
      "id": "M04",
      "version": "Cochrane Handbook 6.5.1 (2025), chapter updated 2025-03",
      "url": "https://www.cochrane.org/authors/handbooks-and-manuals/handbook/current/chapter-04",
      "section": "§4.5, §4.6.1–4.6.3, MECIR C42",
      "official_principle": "Distinguish studies from reports and link them; do not omit a study solely because results are unreported.",
      "review_level": "Existing methodological links were reused for production. External originals were not reread and methodological content was not reassessed."
    },
    {
      "id": "M08",
      "version": "Cochrane Handbook 6.5 (2024), chapter updated 2019-10",
      "url": "https://www.cochrane.org/authors/handbooks-and-manuals/handbook/current/chapter-08",
      "section": "§8.1–8.2.3, Table 8.2.a",
      "official_principle": "Define the outcome and effect of interest, then examine randomization, deviations, missing data, measurement and selective reporting.",
      "review_level": "Existing methodological links were reused for production. External originals were not reread and methodological content was not reassessed."
    },
    {
      "id": "M15",
      "version": "Cochrane Handbook 6.5 (2024), chapter updated 2023-08",
      "url": "https://www.cochrane.org/authors/handbooks-and-manuals/handbook/current/chapter-15",
      "section": "§15.2.4, §15.3.1–15.3.3",
      "official_principle": "Distinguish effect estimates, intervals, importance and applicability. Sample size alone does not determine precision.",
      "review_level": "Existing methodological links were reused for production. External originals were not reread and methodological content was not reassessed."
    },
    {
      "id": "M19",
      "version": "Cochrane Handbook 6.5 (2024), chapter updated 2019-10",
      "url": "https://www.cochrane.org/authors/handbooks-and-manuals/handbook/current/chapter-19",
      "section": "§19.1.2, §19.2.1–19.2.4",
      "official_principle": "Harm questions may require different designs, populations and follow-up from efficacy questions. Case reports do not establish incidence rates.",
      "review_level": "Existing methodological links were reused for production. External originals were not reread and methodological content was not reassessed."
    }
  ],
  "status_dictionary": {
    "Partly verified": "Some information is present in the stored source, with detailed original materials still unverified; this does not mean review passed or clinical efficacy certified",
    "Unverified": "Detailed materials for the selected condition could not be established within the stored scope; this does not mean zero effect, zero studies or safety",
    "Review incomplete": "Awaiting user review",
    "Met": "Use only within the relevant condition's scope after user review; no automatic display in this preparation",
    "Not reported": "Distinguish only within materials actually read; do not turn unread external materials into unreported findings",
    "Inaccessible": "Not applied during this preparation because actual access was not tested",
    "Not applicable": "Use with a reason for non-applicability based on an explicit question boundary",
    "Conflicting data": "Judge after actual material comparison; review was not performed during this preparation",
    "Insufficient evidence for the conditions": "Do not use as a clinical grade encompassing currently unread materials"
  },
  "requirements": [
    {
      "item_id": "N01",
      "question_type": "Evidence condition",
      "question": "Which supervised office-SBP claim is selected?",
      "needed": "Selected claim, grade, note and measurement-setting boundaries",
      "role": "Required",
      "role_reason": "This condition connects Selected claim, grade, note and measurement-setting boundaries with supervised office SBP, omnibus tests, specific comparisons, within-group changes, measurement settings, denominators, attrition, directness and harm boundaries.",
      "application_exception": "Preserve selected C and the note supporting the direction in small trials while specific adjusted effects remain unverified. Distinguish absent subclaim score/status/axes from parent C with 50 points. Omnibus tests, within-group changes and other measurement settings do not become new specific effects, CIs or independent replication. Create no new grades, safety certification or exercise, breathing, medication or treatment instructions.",
      "criterion": "Material for Selected claim, grade, note and measurement-setting boundaries must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.",
      "basis": "Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.",
      "condition_origin": "Internally applied conditions preserved for the existing subclaim. They do not establish preregistration, official-tool certification or completed content review.",
      "proposed_research": "Material needed: Supervision, comparator, timing, denominators and adjusted direct effects/CIs are unverified. Create no new independent claims or scores. This records needed materials; no new research was executed."
    },
    {
      "item_id": "N02",
      "question_type": "Evidence condition",
      "question": "What is Farah's office-SBP test across 3 arms?",
      "needed": "Omnibus group-by-time test, original model and denominators",
      "role": "Required",
      "role_reason": "This condition connects Omnibus group-by-time test, original model and denominators with supervised office SBP, omnibus tests, specific comparisons, within-group changes, measurement settings, denominators, attrition, directness and harm boundaries.",
      "application_exception": "Preserve selected C and the note supporting the direction in small trials while specific adjusted effects remain unverified. Distinguish absent subclaim score/status/axes from parent C with 50 points. Omnibus tests, within-group changes and other measurement settings do not become new specific effects, CIs or independent replication. Create no new grades, safety certification or exercise, breathing, medication or treatment instructions.",
      "criterion": "Material for Omnibus group-by-time test, original model and denominators must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.",
      "basis": "Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.",
      "condition_origin": "Internally applied conditions preserved for the existing subclaim. They do not establish preregistration, official-tool certification or completed content review.",
      "proposed_research": "Material needed: Original models, arm/time values, adjusted pairwise comparisons, denominators, direct effects/95% CIs and multiple comparisons are unverified. This P alone does not establish specific pairwise effects. This records needed materials; no new research was executed."
    },
    {
      "item_id": "N03",
      "question_type": "Evidence condition",
      "question": "Which pairwise difference does the omnibus test establish?",
      "needed": "Omnibus 3-arm testing versus specific adjusted comparisons",
      "role": "Required",
      "role_reason": "This condition connects Omnibus 3-arm testing versus specific adjusted comparisons with supervised office SBP, omnibus tests, specific comparisons, within-group changes, measurement settings, denominators, attrition, directness and harm boundaries.",
      "application_exception": "Preserve selected C and the note supporting the direction in small trials while specific adjusted effects remain unverified. Distinguish absent subclaim score/status/axes from parent C with 50 points. Omnibus tests, within-group changes and other measurement settings do not become new specific effects, CIs or independent replication. Create no new grades, safety certification or exercise, breathing, medication or treatment instructions.",
      "criterion": "Material for Omnibus 3-arm testing versus specific adjusted comparisons must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.",
      "basis": "Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.",
      "condition_origin": "Internally applied conditions preserved for the existing subclaim. They do not establish preregistration, official-tool certification or completed content review.",
      "proposed_research": "Material needed: Planned comparisons, baseline adjustment, estimates/CIs, denominators, analysis populations and original tables are unverified. Do not fill in absent pairwise values, CIs or P. This records needed materials; no new research was executed."
    },
    {
      "item_id": "N04",
      "question_type": "Evidence condition",
      "question": "Can SBP and DBP tests be combined?",
      "needed": "Office systolic/diastolic outcomes and precision",
      "role": "Required",
      "role_reason": "This condition connects Office systolic/diastolic outcomes and precision with supervised office SBP, omnibus tests, specific comparisons, within-group changes, measurement settings, denominators, attrition, directness and harm boundaries.",
      "application_exception": "Preserve selected C and the note supporting the direction in small trials while specific adjusted effects remain unverified. Distinguish absent subclaim score/status/axes from parent C with 50 points. Omnibus tests, within-group changes and other measurement settings do not become new specific effects, CIs or independent replication. Create no new grades, safety certification or exercise, breathing, medication or treatment instructions.",
      "criterion": "Material for Office systolic/diastolic outcomes and precision must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.",
      "basis": "Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.",
      "condition_origin": "Internally applied conditions preserved for the existing subclaim. They do not establish preregistration, official-tool certification or completed content review.",
      "proposed_research": "Material needed: Original arm values, specific comparisons, CIs, denominators, planned hierarchy and multiple testing are unverified. Do not copy DBP results into SBP effects. This records needed materials; no new research was executed."
    },
    {
      "item_id": "N05",
      "question_type": "Evidence condition",
      "question": "Are office, central and ambulatory pressure the same outcome?",
      "needed": "Measurement locations, settings, devices, timing and denominators",
      "role": "Required",
      "role_reason": "This condition connects Measurement locations, settings, devices, timing and denominators with supervised office SBP, omnibus tests, specific comparisons, within-group changes, measurement settings, denominators, attrition, directness and harm boundaries.",
      "application_exception": "Preserve selected C and the note supporting the direction in small trials while specific adjusted effects remain unverified. Distinguish absent subclaim score/status/axes from parent C with 50 points. Omnibus tests, within-group changes and other measurement settings do not become new specific effects, CIs or independent replication. Create no new grades, safety certification or exercise, breathing, medication or treatment instructions.",
      "criterion": "Material for Measurement locations, settings, devices, timing and denominators must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.",
      "basis": "Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.",
      "condition_origin": "Internally applied conditions preserved for the existing subclaim. They do not establish preregistration, official-tool certification or completed content review.",
      "proposed_research": "Material needed: Locations, devices, conditions, timing, denominators, between-group comparisons/CIs and planned hierarchy are unverified. Do not estimate central values or combine all as the same SBP effect. This records needed materials; no new research was executed."
    },
    {
      "item_id": "N06",
      "question_type": "Evidence condition",
      "question": "Is a within-group reduction an added benefit over control?",
      "needed": "Within-group changes versus direct between-group effects",
      "role": "Required",
      "role_reason": "This condition connects Within-group changes versus direct between-group effects with supervised office SBP, omnibus tests, specific comparisons, within-group changes, measurement settings, denominators, attrition, directness and harm boundaries.",
      "application_exception": "Preserve selected C and the note supporting the direction in small trials while specific adjusted effects remain unverified. Distinguish absent subclaim score/status/axes from parent C with 50 points. Omnibus tests, within-group changes and other measurement settings do not become new specific effects, CIs or independent replication. Create no new grades, safety certification or exercise, breathing, medication or treatment instructions.",
      "criterion": "Material for Within-group changes versus direct between-group effects must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.",
      "basis": "Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.",
      "condition_origin": "Internally applied conditions preserved for the existing subclaim. They do not establish preregistration, official-tool certification or completed content review.",
      "proposed_research": "Material needed: Baseline/follow-up values, adjusted models, specific comparisons, arm denominators and original effects/CIs are unverified. Do not subtract changes to create new control-relative effects. This records needed materials; no new research was executed."
    },
    {
      "item_id": "N07",
      "question_type": "Evidence condition",
      "question": "Were figure/table arm-label inconsistencies resolved?",
      "needed": "Original figures, tables, legends and arm attribution",
      "role": "Required",
      "role_reason": "This condition connects Original figures, tables, legends and arm attribution with supervised office SBP, omnibus tests, specific comparisons, within-group changes, measurement settings, denominators, attrition, directness and harm boundaries.",
      "application_exception": "Preserve selected C and the note supporting the direction in small trials while specific adjusted effects remain unverified. Distinguish absent subclaim score/status/axes from parent C with 50 points. Omnibus tests, within-group changes and other measurement settings do not become new specific effects, CIs or independent replication. Create no new grades, safety certification or exercise, breathing, medication or treatment instructions.",
      "criterion": "Material for Original figures, tables, legends and arm attribution must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.",
      "basis": "Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.",
      "condition_origin": "Internally applied conditions preserved for the existing subclaim. They do not establish preregistration, official-tool certification or completed content review.",
      "proposed_research": "Material needed: Complete original figures/tables, legends, arm keys, underlying data, explanations and corrections are needed. Production did not resolve these inconsistencies or edit values. This records needed materials; no new research was executed."
    },
    {
      "item_id": "N08",
      "question_type": "Evidence condition",
      "question": "What were Palmeira's supportive and null results?",
      "needed": "Office-SBP interaction versus DBP and ambulatory pressure",
      "role": "Required",
      "role_reason": "This condition connects Office-SBP interaction versus DBP and ambulatory pressure with supervised office SBP, omnibus tests, specific comparisons, within-group changes, measurement settings, denominators, attrition, directness and harm boundaries.",
      "application_exception": "Preserve selected C and the note supporting the direction in small trials while specific adjusted effects remain unverified. Distinguish absent subclaim score/status/axes from parent C with 50 points. Omnibus tests, within-group changes and other measurement settings do not become new specific effects, CIs or independent replication. Create no new grades, safety certification or exercise, breathing, medication or treatment instructions.",
      "criterion": "Material for Office-SBP interaction versus DBP and ambulatory pressure must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.",
      "basis": "Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.",
      "condition_origin": "Internally applied conditions preserved for the existing subclaim. They do not establish preregistration, official-tool certification or completed content review.",
      "proposed_research": "Material needed: Original models, arm denominators, baseline/follow-up, endpoint comparisons/CIs and planned analyses are unverified. Do not copy Farah P into this report. This records needed materials; no new research was executed."
    },
    {
      "item_id": "N09",
      "question_type": "Evidence condition",
      "question": "Were large attrition and analysis denominators verified?",
      "needed": "Randomization, completion, missingness, ITT, sensitivity and time-specific denominators",
      "role": "Required",
      "role_reason": "This condition connects Randomization, completion, missingness, ITT, sensitivity and time-specific denominators with supervised office SBP, omnibus tests, specific comparisons, within-group changes, measurement settings, denominators, attrition, directness and harm boundaries.",
      "application_exception": "Preserve selected C and the note supporting the direction in small trials while specific adjusted effects remain unverified. Distinguish absent subclaim score/status/axes from parent C with 50 points. Omnibus tests, within-group changes and other measurement settings do not become new specific effects, CIs or independent replication. Create no new grades, safety certification or exercise, breathing, medication or treatment instructions.",
      "criterion": "Material for Randomization, completion, missingness, ITT, sensitivity and time-specific denominators must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.",
      "basis": "Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.",
      "condition_origin": "Internally applied conditions preserved for the existing subclaim. They do not establish preregistration, official-tool certification or completed content review.",
      "proposed_research": "Material needed: Original flow charts, arm allocation/completion, missingness/withdrawal reasons, ITT, analyses, sensitivity and time-specific denominators are unverified. Calculate no new withdrawal counts, rates or effects. This records needed materials; no new research was executed."
    },
    {
      "item_id": "N10",
      "question_type": "Evidence condition",
      "question": "Can supervised results be transferred to home training?",
      "needed": "Training location, supervision, contact, actual exposure and adherence",
      "role": "Required",
      "role_reason": "This condition connects Training location, supervision, contact, actual exposure and adherence with supervised office SBP, omnibus tests, specific comparisons, within-group changes, measurement settings, denominators, attrition, directness and harm boundaries.",
      "application_exception": "Preserve selected C and the note supporting the direction in small trials while specific adjusted effects remain unverified. Distinguish absent subclaim score/status/axes from parent C with 50 points. Omnibus tests, within-group changes and other measurement settings do not become new specific effects, CIs or independent replication. Create no new grades, safety certification or exercise, breathing, medication or treatment instructions.",
      "criterion": "Material for Training location, supervision, contact, actual exposure and adherence must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.",
      "basis": "Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.",
      "condition_origin": "Internally applied conditions preserved for the existing subclaim. They do not establish preregistration, official-tool certification or completed content review.",
      "proposed_research": "Material needed: Actual intensity, exposure, contact, adherence, comparators and original comparisons/denominators are unverified. Do not equate supervised/home conditions or create new exercise methods. This records needed materials; no new research was executed."
    },
    {
      "item_id": "N11",
      "question_type": "Evidence condition",
      "question": "Are home training and home pressure measurement the same?",
      "needed": "Intervention delivery location versus outcome measurement setting",
      "role": "Required",
      "role_reason": "This condition connects Intervention delivery location versus outcome measurement setting with supervised office SBP, omnibus tests, specific comparisons, within-group changes, measurement settings, denominators, attrition, directness and harm boundaries.",
      "application_exception": "Preserve selected C and the note supporting the direction in small trials while specific adjusted effects remain unverified. Distinguish absent subclaim score/status/axes from parent C with 50 points. Omnibus tests, within-group changes and other measurement settings do not become new specific effects, CIs or independent replication. Create no new grades, safety certification or exercise, breathing, medication or treatment instructions.",
      "criterion": "Material for Intervention delivery location versus outcome measurement setting must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.",
      "basis": "Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.",
      "condition_origin": "Internally applied conditions preserved for the existing subclaim. They do not establish preregistration, official-tool certification or completed content review.",
      "proposed_research": "Material needed: Original data separating training location/supervision from measurement location, devices, schedules, denominators, timing and specific comparisons are needed. Exact home-pressure effects are absent from the summary. This records needed materials; no new research was executed."
    },
    {
      "item_id": "N12",
      "question_type": "Evidence condition",
      "question": "How does null 24-hour pressure limit the office signal?",
      "needed": "Setting-specific tests, original values, between-group effects and denominators",
      "role": "Required",
      "role_reason": "This condition connects Setting-specific tests, original values, between-group effects and denominators with supervised office SBP, omnibus tests, specific comparisons, within-group changes, measurement settings, denominators, attrition, directness and harm boundaries.",
      "application_exception": "Preserve selected C and the note supporting the direction in small trials while specific adjusted effects remain unverified. Distinguish absent subclaim score/status/axes from parent C with 50 points. Omnibus tests, within-group changes and other measurement settings do not become new specific effects, CIs or independent replication. Create no new grades, safety certification or exercise, breathing, medication or treatment instructions.",
      "criterion": "Material for Setting-specific tests, original values, between-group effects and denominators must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.",
      "basis": "Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.",
      "condition_origin": "Internally applied conditions preserved for the existing subclaim. They do not establish preregistration, official-tool certification or completed content review.",
      "proposed_research": "Material needed: Setting-specific original values, between-group CIs, denominators, devices, valid measurements, timing and effects of interest are unverified. Null does not certify exact effect 0 or equivalence. This records needed materials; no new research was executed."
    },
    {
      "item_id": "N13",
      "question_type": "Evidence condition",
      "question": "Does office SBP establish day/night or clinical-event benefit?",
      "needed": "Surrogates, day/night/ambulatory pressure and long-term clinical-event boundaries",
      "role": "Required",
      "role_reason": "This condition connects Surrogates, day/night/ambulatory pressure and long-term clinical-event boundaries with supervised office SBP, omnibus tests, specific comparisons, within-group changes, measurement settings, denominators, attrition, directness and harm boundaries.",
      "application_exception": "Preserve selected C and the note supporting the direction in small trials while specific adjusted effects remain unverified. Distinguish absent subclaim score/status/axes from parent C with 50 points. Omnibus tests, within-group changes and other measurement settings do not become new specific effects, CIs or independent replication. Create no new grades, safety certification or exercise, breathing, medication or treatment instructions.",
      "criterion": "Material for Surrogates, day/night/ambulatory pressure and long-term clinical-event boundaries must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.",
      "basis": "Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.",
      "condition_origin": "Internally applied conditions preserved for the existing subclaim. They do not establish preregistration, official-tool certification or completed content review.",
      "proposed_research": "Material needed: Day/night definitions, measurements/denominators, between-group effects/CIs, clinical importance and direct long-term event data are needed. Create no new medication reduction/replacement or treatment instructions. This records needed materials; no new research was executed."
    },
    {
      "item_id": "N14",
      "question_type": "Evidence condition",
      "question": "Do signals across studies establish precise independent replication?",
      "needed": "Matched supervision/controls, institutions, recruitment and report/participant relationships",
      "role": "Required",
      "role_reason": "This condition connects Matched supervision/controls, institutions, recruitment and report/participant relationships with supervised office SBP, omnibus tests, specific comparisons, within-group changes, measurement settings, denominators, attrition, directness and harm boundaries.",
      "application_exception": "Preserve selected C and the note supporting the direction in small trials while specific adjusted effects remain unverified. Distinguish absent subclaim score/status/axes from parent C with 50 points. Omnibus tests, within-group changes and other measurement settings do not become new specific effects, CIs or independent replication. Create no new grades, safety certification or exercise, breathing, medication or treatment instructions.",
      "criterion": "Material for Matched supervision/controls, institutions, recruitment and report/participant relationships must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.",
      "basis": "Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.",
      "condition_origin": "Internally applied conditions preserved for the existing subclaim. They do not establish preregistration, official-tool certification or completed content review.",
      "proposed_research": "Material needed: Institutions, recruitment/registration, support, report/participant overlap, matched supervision/controls and original effects/CIs are unverified. Do not fill in unique-trial/participant totals. This records needed materials; no new research was executed."
    },
    {
      "item_id": "N15",
      "question_type": "Evidence condition",
      "question": "Who were the participants and what was their medication status?",
      "needed": "Diagnosis, baseline control, medication, age, comorbidities and eligibility",
      "role": "Required",
      "role_reason": "This condition connects Diagnosis, baseline control, medication, age, comorbidities and eligibility with supervised office SBP, omnibus tests, specific comparisons, within-group changes, measurement settings, denominators, attrition, directness and harm boundaries.",
      "application_exception": "Preserve selected C and the note supporting the direction in small trials while specific adjusted effects remain unverified. Distinguish absent subclaim score/status/axes from parent C with 50 points. Omnibus tests, within-group changes and other measurement settings do not become new specific effects, CIs or independent replication. Create no new grades, safety certification or exercise, breathing, medication or treatment instructions.",
      "criterion": "Material for Diagnosis, baseline control, medication, age, comorbidities and eligibility must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.",
      "basis": "Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.",
      "condition_origin": "Internally applied conditions preserved for the existing subclaim. They do not establish preregistration, official-tool certification or completed content review.",
      "proposed_research": "Material needed: Diagnosis, baseline control, medication/changes, age, comorbidities, recruitment/exclusions and arm denominators are unverified. Do not extend this to untreated, other-patient or vulnerable populations. This records needed materials; no new research was executed."
    },
    {
      "item_id": "N16",
      "question_type": "Evidence condition",
      "question": "Are representative training conditions instructions?",
      "needed": "Original intensity, exposure, delivery and actual adherence",
      "role": "Supplementary",
      "role_reason": "This condition connects Original intensity, exposure, delivery and actual adherence with supervised office SBP, omnibus tests, specific comparisons, within-group changes, measurement settings, denominators, attrition, directness and harm boundaries.",
      "application_exception": "Preserve selected C and the note supporting the direction in small trials while specific adjusted effects remain unverified. Distinguish absent subclaim score/status/axes from parent C with 50 points. Omnibus tests, within-group changes and other measurement settings do not become new specific effects, CIs or independent replication. Create no new grades, safety certification or exercise, breathing, medication or treatment instructions.",
      "criterion": "Material for Original intensity, exposure, delivery and actual adherence must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.",
      "basis": "Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.",
      "condition_origin": "Internally applied conditions preserved for the existing subclaim. They do not establish preregistration, official-tool certification or completed content review.",
      "proposed_research": "Material needed: Original devices, intensity measurement, exposure/sessions, supervision/contact, adherence and control records are needed. Calculate no new total time/exposure or exercise, breathing or treatment steps. This records needed materials; no new research was executed."
    },
    {
      "item_id": "N17",
      "question_type": "Evidence condition",
      "question": "Were different comparators distinguished?",
      "needed": "Sham, no-exercise and aerobic controls and effects of interest",
      "role": "Required",
      "role_reason": "This condition connects Sham, no-exercise and aerobic controls and effects of interest with supervised office SBP, omnibus tests, specific comparisons, within-group changes, measurement settings, denominators, attrition, directness and harm boundaries.",
      "application_exception": "Preserve selected C and the note supporting the direction in small trials while specific adjusted effects remain unverified. Distinguish absent subclaim score/status/axes from parent C with 50 points. Omnibus tests, within-group changes and other measurement settings do not become new specific effects, CIs or independent replication. Create no new grades, safety certification or exercise, breathing, medication or treatment instructions.",
      "criterion": "Material for Sham, no-exercise and aerobic controls and effects of interest must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.",
      "basis": "Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.",
      "condition_origin": "Internally applied conditions preserved for the existing subclaim. They do not establish preregistration, official-tool certification or completed content review.",
      "proposed_research": "Material needed: Report-specific control intensity, exposure, contact, baseline adjustment, planned comparisons and denominators are unverified. Do not interchange comparator-specific effects. This records needed materials; no new research was executed."
    },
    {
      "item_id": "N18",
      "question_type": "Evidence condition",
      "question": "Were concurrent medication, activity and supervisory contact verified?",
      "needed": "Concurrent treatment, changes, actual exposure, measurement conditions and attribution",
      "role": "Required",
      "role_reason": "This condition connects Concurrent treatment, changes, actual exposure, measurement conditions and attribution with supervised office SBP, omnibus tests, specific comparisons, within-group changes, measurement settings, denominators, attrition, directness and harm boundaries.",
      "application_exception": "Preserve selected C and the note supporting the direction in small trials while specific adjusted effects remain unverified. Distinguish absent subclaim score/status/axes from parent C with 50 points. Omnibus tests, within-group changes and other measurement settings do not become new specific effects, CIs or independent replication. Create no new grades, safety certification or exercise, breathing, medication or treatment instructions.",
      "criterion": "Material for Concurrent treatment, changes, actual exposure, measurement conditions and attribution must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.",
      "basis": "Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.",
      "condition_origin": "Internally applied conditions preserved for the existing subclaim. They do not establish preregistration, official-tool certification or completed content review.",
      "proposed_research": "Material needed: Arm medication/changes, concurrent activity, adherence, measurement conditions, models, denominators and original effects are needed. Do not establish identical conditions or effects without medication. This records needed materials; no new research was executed."
    },
    {
      "item_id": "N19",
      "question_type": "Evidence condition",
      "question": "Were randomization, blinding, measurement and timing verified?",
      "needed": "Allocation, concealment, evaluators, standardized measurement, planning and missingness",
      "role": "Required",
      "role_reason": "This condition connects Allocation, concealment, evaluators, standardized measurement, planning and missingness with supervised office SBP, omnibus tests, specific comparisons, within-group changes, measurement settings, denominators, attrition, directness and harm boundaries.",
      "application_exception": "Preserve selected C and the note supporting the direction in small trials while specific adjusted effects remain unverified. Distinguish absent subclaim score/status/axes from parent C with 50 points. Omnibus tests, within-group changes and other measurement settings do not become new specific effects, CIs or independent replication. Create no new grades, safety certification or exercise, breathing, medication or treatment instructions.",
      "criterion": "Material for Allocation, concealment, evaluators, standardized measurement, planning and missingness must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.",
      "basis": "Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.",
      "condition_origin": "Internally applied conditions preserved for the existing subclaim. They do not establish preregistration, official-tool certification or completed content review.",
      "proposed_research": "Material needed: Original methods, measurement procedures, blinding, baseline adjustment/missingness, planned endpoints/comparisons/timing and analysis plans are needed. Create no official method-assessment pass or new grade. This records needed materials; no new research was executed."
    },
    {
      "item_id": "N20",
      "question_type": "Evidence condition",
      "question": "Are registration identifiers equivalent to reading original plans?",
      "needed": "Registration, paper linkage, changes, protocols, SAPs and planned endpoints",
      "role": "Required",
      "role_reason": "This condition connects Registration, paper linkage, changes, protocols, SAPs and planned endpoints with supervised office SBP, omnibus tests, specific comparisons, within-group changes, measurement settings, denominators, attrition, directness and harm boundaries.",
      "application_exception": "Preserve selected C and the note supporting the direction in small trials while specific adjusted effects remain unverified. Distinguish absent subclaim score/status/axes from parent C with 50 points. Omnibus tests, within-group changes and other measurement settings do not become new specific effects, CIs or independent replication. Create no new grades, safety certification or exercise, breathing, medication or treatment instructions.",
      "criterion": "Material for Registration, paper linkage, changes, protocols, SAPs and planned endpoints must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.",
      "basis": "Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.",
      "condition_origin": "Internally applied conditions preserved for the existing subclaim. They do not establish preregistration, official-tool certification or completed content review.",
      "proposed_research": "Material needed: Original registration, changes, paper linkage, protocols/SAPs, planned endpoints, arm comparisons and denominators are needed. Identifiers, URLs and PMCID alone do not establish reading or prospective verification. This records needed materials; no new research was executed."
    },
    {
      "item_id": "N21",
      "question_type": "Evidence condition",
      "question": "What were funding, products, employee authors and design/analysis roles?",
      "needed": "Financial/device/product support, author affiliations and design/analysis/publication control",
      "role": "Required",
      "role_reason": "This condition connects Financial/device/product support, author affiliations and design/analysis/publication control with supervised office SBP, omnibus tests, specific comparisons, within-group changes, measurement settings, denominators, attrition, directness and harm boundaries.",
      "application_exception": "Preserve selected C and the note supporting the direction in small trials while specific adjusted effects remain unverified. Distinguish absent subclaim score/status/axes from parent C with 50 points. Omnibus tests, within-group changes and other measurement settings do not become new specific effects, CIs or independent replication. Create no new grades, safety certification or exercise, breathing, medication or treatment instructions.",
      "criterion": "Material for Financial/device/product support, author affiliations and design/analysis/publication control must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.",
      "basis": "Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.",
      "condition_origin": "Internally applied conditions preserved for the existing subclaim. They do not establish preregistration, official-tool certification or completed content review.",
      "proposed_research": "Material needed: Disclosures of financial/device/product support, company/author affiliations, design/analysis/publication roles and institutional, recruitment and report relationships are unread. Do not fill in no support or involvement. This records needed materials; no new research was executed."
    },
    {
      "item_id": "N22",
      "question_type": "Evidence condition",
      "question": "Were pain, exercise pressure and vulnerable-group harms verified?",
      "needed": "Events, affected people, arm denominators, exposure, collection, stopping and follow-up",
      "role": "Supplementary",
      "role_reason": "This condition connects Events, affected people, arm denominators, exposure, collection, stopping and follow-up with supervised office SBP, omnibus tests, specific comparisons, within-group changes, measurement settings, denominators, attrition, directness and harm boundaries.",
      "application_exception": "Preserve selected C and the note supporting the direction in small trials while specific adjusted effects remain unverified. Distinguish absent subclaim score/status/axes from parent C with 50 points. Omnibus tests, within-group changes and other measurement settings do not become new specific effects, CIs or independent replication. Create no new grades, safety certification or exercise, breathing, medication or treatment instructions.",
      "criterion": "Material for Events, affected people, arm denominators, exposure, collection, stopping and follow-up must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.",
      "basis": "Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.",
      "condition_origin": "Internally applied conditions preserved for the existing subclaim. They do not establish preregistration, official-tool certification or completed content review.",
      "proposed_research": "Material needed: Harm collection, severity/timing, events/affected people, denominators, actual exposure, stopping, medication/vulnerable groups and long-term data are needed. Null ambulatory pressure does not become no harm or safety certification. This records needed materials; no new research was executed."
    },
    {
      "item_id": "N23",
      "question_type": "Evidence condition",
      "question": "Are subclaim grades the same as parent scores and axes?",
      "needed": "Absent subclaim score/status/axes versus the parent verdict",
      "role": "Required",
      "role_reason": "This condition connects Absent subclaim score/status/axes versus the parent verdict with supervised office SBP, omnibus tests, specific comparisons, within-group changes, measurement settings, denominators, attrition, directness and harm boundaries.",
      "application_exception": "Preserve selected C and the note supporting the direction in small trials while specific adjusted effects remain unverified. Distinguish absent subclaim score/status/axes from parent C with 50 points. Omnibus tests, within-group changes and other measurement settings do not become new specific effects, CIs or independent replication. Create no new grades, safety certification or exercise, breathing, medication or treatment instructions.",
      "criterion": "Material for Absent subclaim score/status/axes versus the parent verdict must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.",
      "basis": "Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.",
      "condition_origin": "Internally applied conditions preserved for the existing subclaim. They do not establish preregistration, official-tool certification or completed content review.",
      "proposed_research": "Material needed: Do not fill subclaims with parent scores/axes or turn unrecorded precision into default values, new scores or independence certification. Distinguish parent/subclaim application boundaries. This records needed materials; no new research was executed."
    },
    {
      "item_id": "N24",
      "question_type": "Evidence condition",
      "question": "How are representative information and both languages preserved?",
      "needed": "Report-specific populations, supervision, measurement settings, outcomes, timing and denominators",
      "role": "Required",
      "role_reason": "This condition connects Report-specific populations, supervision, measurement settings, outcomes, timing and denominators with supervised office SBP, omnibus tests, specific comparisons, within-group changes, measurement settings, denominators, attrition, directness and harm boundaries.",
      "application_exception": "Preserve selected C and the note supporting the direction in small trials while specific adjusted effects remain unverified. Distinguish absent subclaim score/status/axes from parent C with 50 points. Omnibus tests, within-group changes and other measurement settings do not become new specific effects, CIs or independent replication. Create no new grades, safety certification or exercise, breathing, medication or treatment instructions.",
      "criterion": "Material for Report-specific populations, supervision, measurement settings, outcomes, timing and denominators must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.",
      "basis": "Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.",
      "condition_origin": "Internally applied conditions preserved for the existing subclaim. They do not establish preregistration, official-tool certification or completed content review.",
      "proposed_research": "Material needed: Report-specific delivery, supervision, measurement settings, endpoints, timing, denominators and original English comparison materials are needed. No external English comparison or correction review was performed this run. This records needed materials; no new research was executed."
    },
    {
      "item_id": "N25",
      "question_type": "Evidence condition",
      "question": "How are actual reading and report/material counts distinguished?",
      "needed": "Stored summaries, external reading and trial/report/cohort relationships",
      "role": "Required",
      "role_reason": "This condition connects Stored summaries, external reading and trial/report/cohort relationships with supervised office SBP, omnibus tests, specific comparisons, within-group changes, measurement settings, denominators, attrition, directness and harm boundaries.",
      "application_exception": "Preserve selected C and the note supporting the direction in small trials while specific adjusted effects remain unverified. Distinguish absent subclaim score/status/axes from parent C with 50 points. Omnibus tests, within-group changes and other measurement settings do not become new specific effects, CIs or independent replication. Create no new grades, safety certification or exercise, breathing, medication or treatment instructions.",
      "criterion": "Material for Stored summaries, external reading and trial/report/cohort relationships must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.",
      "basis": "Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.",
      "condition_origin": "Internally applied conditions preserved for the existing subclaim. They do not establish preregistration, official-tool certification or completed content review.",
      "proposed_research": "Material needed: Original-material acquisition, actual reading and trial/report/cohort relationships are unverified. URLs/identifiers alone do not establish completed reading or unique-trial/participant totals. This records needed materials; no new research was executed."
    },
    {
      "item_id": "N26",
      "question_type": "Evidence condition",
      "question": "What are the evidence date and correction history?",
      "needed": "Original date, empty correction/deliberation records, production timing and original URLs",
      "role": "Required",
      "role_reason": "This condition connects Original date, empty correction/deliberation records, production timing and original URLs with supervised office SBP, omnibus tests, specific comparisons, within-group changes, measurement settings, denominators, attrition, directness and harm boundaries.",
      "application_exception": "Preserve selected C and the note supporting the direction in small trials while specific adjusted effects remain unverified. Distinguish absent subclaim score/status/axes from parent C with 50 points. Omnibus tests, within-group changes and other measurement settings do not become new specific effects, CIs or independent replication. Create no new grades, safety certification or exercise, breathing, medication or treatment instructions.",
      "criterion": "Material for Original date, empty correction/deliberation records, production timing and original URLs must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.",
      "basis": "Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.",
      "condition_origin": "Internally applied conditions preserved for the existing subclaim. They do not establish preregistration, official-tool certification or completed content review.",
      "proposed_research": "Material needed: When originals/corrections are acquired, preserve and link complete texts, events, versions and reasons. No original-verdict change or external lookup was performed this run. This records needed materials; no new research was executed."
    },
    {
      "item_id": "N27",
      "question_type": "Evidence condition",
      "question": "How will new materials and changed questions be updated?",
      "needed": "Evidence updates, criteria revisions and original-verdict changes",
      "role": "Required",
      "role_reason": "This condition connects Evidence updates, criteria revisions and original-verdict changes with supervised office SBP, omnibus tests, specific comparisons, within-group changes, measurement settings, denominators, attrition, directness and harm boundaries.",
      "application_exception": "Preserve selected C and the note supporting the direction in small trials while specific adjusted effects remain unverified. Distinguish absent subclaim score/status/axes from parent C with 50 points. Omnibus tests, within-group changes and other measurement settings do not become new specific effects, CIs or independent replication. Create no new grades, safety certification or exercise, breathing, medication or treatment instructions.",
      "criterion": "Material for Evidence updates, criteria revisions and original-verdict changes must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.",
      "basis": "Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.",
      "condition_origin": "Internally applied conditions preserved for the existing subclaim. They do not establish preregistration, official-tool certification or completed content review.",
      "proposed_research": "Material needed: Updates must retain complete texts, criteria versions, events and reasons. Do not invent clinical calculations, effects/CIs, independence certification, exercise methods, pressure-medication reduction/replacement or treatment instructions. This records needed materials; no new research was executed."
    }
  ]
}