{ "schema_version": "chamgap-public-criteria-1.0", "title": "Wall-sit training × diastolic pressure: key null result, 4-week signal and gaps", "language": "en", "translation_date": "2026-10-16", "criteria_version": "1.0", "criteria_date": "2026-10-06", "condition_origin": "Chamgap's own application conditions", "method_sources": [ { "id": "M03", "version": "Cochrane Handbook 6.5 (2024), chapter updated 2023-08", "url": "https://www.cochrane.org/authors/handbooks-and-manuals/handbook/current/chapter-03", "section": "§3.1, §3.2.1–3.2.3, MECIR C5/C7/C13", "official_principle": "Clearly record the question, eligibility conditions and reasons for changes, and distinguish variations in interventions.", "review_level": "Existing methodological links were reused for production. External originals were not reread and methodological content was not reassessed." }, { "id": "M04", "version": "Cochrane Handbook 6.5.1 (2025), chapter updated 2025-03", "url": "https://www.cochrane.org/authors/handbooks-and-manuals/handbook/current/chapter-04", "section": "§4.5, §4.6.1–4.6.3, MECIR C42", "official_principle": "Distinguish studies from reports and link them; do not omit a study solely because results are unreported.", "review_level": "Existing methodological links were reused for production. External originals were not reread and methodological content was not reassessed." }, { "id": "M08", "version": "Cochrane Handbook 6.5 (2024), chapter updated 2019-10", "url": "https://www.cochrane.org/authors/handbooks-and-manuals/handbook/current/chapter-08", "section": "§8.1–8.2.3, Table 8.2.a", "official_principle": "Define the outcome and effect of interest, then examine randomization, deviations, missing data, measurement and selective reporting.", "review_level": "Existing methodological links were reused for production. External originals were not reread and methodological content was not reassessed." }, { "id": "M15", "version": "Cochrane Handbook 6.5 (2024), chapter updated 2023-08", "url": "https://www.cochrane.org/authors/handbooks-and-manuals/handbook/current/chapter-15", "section": "§15.2.4, §15.3.1–15.3.3", "official_principle": "Distinguish effect estimates, intervals, importance and applicability. Sample size alone does not determine precision.", "review_level": "Existing methodological links were reused for production. External originals were not reread and methodological content was not reassessed." }, { "id": "M19", "version": "Cochrane Handbook 6.5 (2024), chapter updated 2019-10", "url": "https://www.cochrane.org/authors/handbooks-and-manuals/handbook/current/chapter-19", "section": "§19.1.2, §19.2.1–19.2.4", "official_principle": "Harm questions may require different designs, populations and follow-up from efficacy questions. Case reports do not establish incidence rates.", "review_level": "Existing methodological links were reused for production. External originals were not reread and methodological content was not reassessed." } ], "status_dictionary": { "Partly verified": "Some information is present in the stored source, with detailed original materials still unverified; this does not mean review passed or clinical efficacy certified", "Unverified": "Detailed materials for the selected condition could not be established within the stored scope; this does not mean zero effect, zero studies or safety", "Review incomplete": "Awaiting user review", "Met": "Use only within the relevant condition's scope after user review; no automatic display in this preparation", "Not reported": "Distinguish only within materials actually read; do not turn unread external materials into unreported findings", "Inaccessible": "Not applied during this preparation because actual access was not tested", "Not applicable": "Use with a reason for non-applicability based on an explicit question boundary", "Conflicting data": "Judge after actual material comparison; review was not performed during this preparation", "Insufficient evidence for the conditions": "Do not use as a clinical grade encompassing currently unread materials" }, "requirements": [ { "item_id": "N01", "question_type": "Evidence condition", "question": "Which diastolic-pressure claim is selected?", "needed": "Exact subclaim, original grade/note and parent verdict", "role": "Required", "role_reason": "This condition connects Exact subclaim, original grade/note and parent verdict with selected resting diastolic pressure, key null versus separate supportive results, and measurement, denominator, duration, comparator, support and harm boundaries.", "application_exception": "Preserve selected subclaim D and the key null between-group note. Distinguish absent subclaim score/status/axes from parent grade C with 54 points. A null result does not establish an effect of 0 or equivalence; SBP values are not transferred to DBP. Create no new effects, CIs, totals, grades, independence/safety certification or exercise, breathing, medication or treatment instructions.", "criterion": "Material for Exact subclaim, original grade/note and parent verdict must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.", "basis": "Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.", "condition_origin": "Internally applied conditions preserved for the existing subclaim. They do not establish preregistration, official-tool certification or completed content review.", "proposed_research": "Material needed: Original DBP definitions, times and comparisons are needed. Do not fill subclaim values with the parent score. This records needed materials; no new research was executed." }, { "item_id": "N02", "question_type": "Evidence condition", "question": "What is the key trial’s between-group DBP result?", "needed": "Direct between-group 12-week resting DBP", "role": "Required", "role_reason": "This condition connects Direct between-group 12-week resting DBP with selected resting diastolic pressure, key null versus separate supportive results, and measurement, denominator, duration, comparator, support and harm boundaries.", "application_exception": "Preserve selected subclaim D and the key null between-group note. Distinguish absent subclaim score/status/axes from parent grade C with 54 points. A null result does not establish an effect of 0 or equivalence; SBP values are not transferred to DBP. Create no new effects, CIs, totals, grades, independence/safety certification or exercise, breathing, medication or treatment instructions.", "criterion": "Material for Direct between-group 12-week resting DBP must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.", "basis": "Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.", "condition_origin": "Internally applied conditions preserved for the existing subclaim. They do not establish preregistration, official-tool certification or completed content review.", "proposed_research": "Material needed: Arm values, adjusted effects, 95% CIs, exact P and analysis tables are needed. Null does not establish an effect of 0 or equivalence. This records needed materials; no new research was executed." }, { "item_id": "N03", "question_type": "Evidence condition", "question": "What does the small sham trial record for DBP?", "needed": "4-week DBP changes versus low-intensity sham/no exercise", "role": "Required", "role_reason": "This condition connects 4-week DBP changes versus low-intensity sham/no exercise with selected resting diastolic pressure, key null versus separate supportive results, and measurement, denominator, duration, comparator, support and harm boundaries.", "application_exception": "Preserve selected subclaim D and the key null between-group note. Distinguish absent subclaim score/status/axes from parent grade C with 54 points. A null result does not establish an effect of 0 or equivalence; SBP values are not transferred to DBP. Create no new effects, CIs, totals, grades, independence/safety certification or exercise, breathing, medication or treatment instructions.", "criterion": "Material for 4-week DBP changes versus low-intensity sham/no exercise must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.", "basis": "Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.", "condition_origin": "Internally applied conditions preserved for the existing subclaim. They do not establish preregistration, official-tool certification or completed content review.", "proposed_research": "Material needed: Estimand, ± definition, comparator-specific effects/CIs/P and arm denominators are needed. Do not convert ±5.0 into a between-group 95% CI. This records needed materials; no new research was executed." }, { "item_id": "N04", "question_type": "Evidence condition", "question": "Are the key null and small supportive results the same?", "needed": "Report-specific DBP directions, designs and durations", "role": "Required", "role_reason": "This condition connects Report-specific DBP directions, designs and durations with selected resting diastolic pressure, key null versus separate supportive results, and measurement, denominator, duration, comparator, support and harm boundaries.", "application_exception": "Preserve selected subclaim D and the key null between-group note. Distinguish absent subclaim score/status/axes from parent grade C with 54 points. A null result does not establish an effect of 0 or equivalence; SBP values are not transferred to DBP. Create no new effects, CIs, totals, grades, independence/safety certification or exercise, breathing, medication or treatment instructions.", "criterion": "Material for Report-specific DBP directions, designs and durations must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.", "basis": "Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.", "condition_origin": "Internally applied conditions preserved for the existing subclaim. They do not establish preregistration, official-tool certification or completed content review.", "proposed_research": "Material needed: Effects, designs/populations, denominators and prospective status for each contrast are needed. Create no pooled effect, independent-replication certification or grade change. This records needed materials; no new research was executed." }, { "item_id": "N05", "question_type": "Evidence condition", "question": "In what setting was resting DBP measured?", "needed": "Office versus ambulatory/home pressure", "role": "Required", "role_reason": "This condition connects Office versus ambulatory/home pressure with selected resting diastolic pressure, key null versus separate supportive results, and measurement, denominator, duration, comparator, support and harm boundaries.", "application_exception": "Preserve selected subclaim D and the key null between-group note. Distinguish absent subclaim score/status/axes from parent grade C with 54 points. A null result does not establish an effect of 0 or equivalence; SBP values are not transferred to DBP. Create no new effects, CIs, totals, grades, independence/safety certification or exercise, breathing, medication or treatment instructions.", "criterion": "Material for Office versus ambulatory/home pressure must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.", "basis": "Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.", "condition_origin": "Internally applied conditions preserved for the existing subclaim. They do not establish preregistration, official-tool certification or completed content review.", "proposed_research": "Material needed: Posture, equipment, repeat/averaging rules, assessor, valid denominators and original tables for other settings are needed. Do not transfer office values to other settings. This records needed materials; no new research was executed." }, { "item_id": "N06", "question_type": "Evidence condition", "question": "Are within-group/simple SBP differences DBP effects?", "needed": "Pressure measures and within-/between-group effects", "role": "Required", "role_reason": "This condition connects Pressure measures and within-/between-group effects with selected resting diastolic pressure, key null versus separate supportive results, and measurement, denominator, duration, comparator, support and harm boundaries.", "application_exception": "Preserve selected subclaim D and the key null between-group note. Distinguish absent subclaim score/status/axes from parent grade C with 54 points. A null result does not establish an effect of 0 or equivalence; SBP values are not transferred to DBP. Create no new effects, CIs, totals, grades, independence/safety certification or exercise, breathing, medication or treatment instructions.", "criterion": "Material for Pressure measures and within-/between-group effects must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.", "basis": "Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.", "condition_origin": "Internally applied conditions preserved for the existing subclaim. They do not establish preregistration, official-tool certification or completed content review.", "proposed_research": "Material needed: DBP-specific tables and direct between-group effects/CIs are needed. Preserve the SBP simple difference as historical; calculate nothing new. This records needed materials; no new research was executed." }, { "item_id": "N07", "question_type": "Evidence condition", "question": "Is DBP precision verified?", "needed": "Analysis unit, effects, intervals and exact tests", "role": "Required", "role_reason": "This condition connects Analysis unit, effects, intervals and exact tests with selected resting diastolic pressure, key null versus separate supportive results, and measurement, denominator, duration, comparator, support and harm boundaries.", "application_exception": "Preserve selected subclaim D and the key null between-group note. Distinguish absent subclaim score/status/axes from parent grade C with 54 points. A null result does not establish an effect of 0 or equivalence; SBP values are not transferred to DBP. Create no new effects, CIs, totals, grades, independence/safety certification or exercise, breathing, medication or treatment instructions.", "criterion": "Material for Analysis unit, effects, intervals and exact tests must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.", "basis": "Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.", "condition_origin": "Internally applied conditions preserved for the existing subclaim. They do not establish preregistration, official-tool certification or completed content review.", "proposed_research": "Material needed: Plans, tables/appendices, models, CIs, variance definitions and missing-data handling are needed. P thresholds or sample size alone do not establish precision. This records needed materials; no new research was executed." }, { "item_id": "N08", "question_type": "Evidence condition", "question": "Are the populations the same?", "needed": "Untreated hypertension versus the separate sham population", "role": "Required", "role_reason": "This condition connects Untreated hypertension versus the separate sham population with selected resting diastolic pressure, key null versus separate supportive results, and measurement, denominator, duration, comparator, support and harm boundaries.", "application_exception": "Preserve selected subclaim D and the key null between-group note. Distinguish absent subclaim score/status/axes from parent grade C with 54 points. A null result does not establish an effect of 0 or equivalence; SBP values are not transferred to DBP. Create no new effects, CIs, totals, grades, independence/safety certification or exercise, breathing, medication or treatment instructions.", "criterion": "Material for Untreated hypertension versus the separate sham population must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.", "basis": "Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.", "condition_origin": "Internally applied conditions preserved for the existing subclaim. They do not establish preregistration, official-tool certification or completed content review.", "proposed_research": "Material needed: Decaux eligibility, baseline pressure, medication and age, plus Cohen arm baselines, are needed. Do not automatically treat the populations as identical untreated hypertension. This records needed materials; no new research was executed." }, { "item_id": "N09", "question_type": "Evidence condition", "question": "What are the actual comparators and DBP contrasts?", "needed": "Handgrip, wall sit/no exercise versus low-intensity sham", "role": "Required", "role_reason": "This condition connects Handgrip, wall sit/no exercise versus low-intensity sham with selected resting diastolic pressure, key null versus separate supportive results, and measurement, denominator, duration, comparator, support and harm boundaries.", "application_exception": "Preserve selected subclaim D and the key null between-group note. Distinguish absent subclaim score/status/axes from parent grade C with 54 points. A null result does not establish an effect of 0 or equivalence; SBP values are not transferred to DBP. Create no new effects, CIs, totals, grades, independence/safety certification or exercise, breathing, medication or treatment instructions.", "criterion": "Material for Handgrip, wall sit/no exercise versus low-intensity sham must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.", "basis": "Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.", "condition_origin": "Internally applied conditions preserved for the existing subclaim. They do not establish preregistration, official-tool certification or completed content review.", "proposed_research": "Material needed: Arm allocation, intensity, cointerventions and comparator-specific DBP models/results are needed. Do not relabel handgrip sham or copy one effect to every control. This records needed materials; no new research was executed." }, { "item_id": "N10", "question_type": "Evidence condition", "question": "Are initial and maintenance DBP distinguished?", "needed": "Initial/maintenance versus separate short-term results", "role": "Required", "role_reason": "This condition connects Initial/maintenance versus separate short-term results with selected resting diastolic pressure, key null versus separate supportive results, and measurement, denominator, duration, comparator, support and harm boundaries.", "application_exception": "Preserve selected subclaim D and the key null between-group note. Distinguish absent subclaim score/status/axes from parent grade C with 54 points. A null result does not establish an effect of 0 or equivalence; SBP values are not transferred to DBP. Create no new effects, CIs, totals, grades, independence/safety certification or exercise, breathing, medication or treatment instructions.", "criterion": "Material for Initial/maintenance versus separate short-term results must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.", "basis": "Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.", "condition_origin": "Internally applied conditions preserved for the existing subclaim. They do not establish preregistration, official-tool certification or completed content review.", "proposed_research": "Material needed: Stage-specific times, denominators, tables and post-training follow-up are needed. Do not extend maintenance to an adequate starting frequency or persistent DBP effects. This records needed materials; no new research was executed." }, { "item_id": "N11", "question_type": "Evidence condition", "question": "Are supervision and intensity retained in scope?", "needed": "Supervision, knee angle, intensity and delivery context", "role": "Required", "role_reason": "This condition connects Supervision, knee angle, intensity and delivery context with selected resting diastolic pressure, key null versus separate supportive results, and measurement, denominator, duration, comparator, support and harm boundaries.", "application_exception": "Preserve selected subclaim D and the key null between-group note. Distinguish absent subclaim score/status/axes from parent grade C with 54 points. A null result does not establish an effect of 0 or equivalence; SBP values are not transferred to DBP. Create no new effects, CIs, totals, grades, independence/safety certification or exercise, breathing, medication or treatment instructions.", "criterion": "Material for Supervision, knee angle, intensity and delivery context must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.", "basis": "Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.", "condition_origin": "Internally applied conditions preserved for the existing subclaim. They do not establish preregistration, official-tool certification or completed content review.", "proposed_research": "Material needed: Report-specific supervision, intensity, adherence and cointerventions are needed. Create no exercise prescription. This records needed materials; no new research was executed." }, { "item_id": "N12", "question_type": "Evidence condition", "question": "What are the original DBP denominators?", "needed": "Allocation/completion versus arm DBP analysis denominators", "role": "Required", "role_reason": "This condition connects Allocation/completion versus arm DBP analysis denominators with selected resting diastolic pressure, key null versus separate supportive results, and measurement, denominator, duration, comparator, support and harm boundaries.", "application_exception": "Preserve selected subclaim D and the key null between-group note. Distinguish absent subclaim score/status/axes from parent grade C with 54 points. A null result does not establish an effect of 0 or equivalence; SBP values are not transferred to DBP. Create no new effects, CIs, totals, grades, independence/safety certification or exercise, breathing, medication or treatment instructions.", "criterion": "Material for Allocation/completion versus arm DBP analysis denominators must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.", "basis": "Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.", "condition_origin": "Internally applied conditions preserved for the existing subclaim. They do not establish preregistration, official-tool certification or completed content review.", "proposed_research": "Material needed: Arm allocation/completion/analysis flow and populations are needed. Do not reuse overall counts for every arm/endpoint or add report counts. This records needed materials; no new research was executed." }, { "item_id": "N13", "question_type": "Evidence condition", "question": "Is DBP’s prospective endpoint status verified?", "needed": "1st/2nd outcomes, prospective times and multiplicity", "role": "Required", "role_reason": "This condition connects 1st/2nd outcomes, prospective times and multiplicity with selected resting diastolic pressure, key null versus separate supportive results, and measurement, denominator, duration, comparator, support and harm boundaries.", "application_exception": "Preserve selected subclaim D and the key null between-group note. Distinguish absent subclaim score/status/axes from parent grade C with 54 points. A null result does not establish an effect of 0 or equivalence; SBP values are not transferred to DBP. Create no new effects, CIs, totals, grades, independence/safety certification or exercise, breathing, medication or treatment instructions.", "criterion": "Material for 1st/2nd outcomes, prospective times and multiplicity must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.", "basis": "Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.", "condition_origin": "Internally applied conditions preserved for the existing subclaim. They do not establish preregistration, official-tool certification or completed content review.", "proposed_research": "Material needed: Dated registration, protocols, SAPs, changes, DBP hierarchy, times and multiplicity plans are needed. External material was not read in this conversion. This records needed materials; no new research was executed." }, { "item_id": "N14", "question_type": "Evidence condition", "question": "Does DBP establish events or medication replacement?", "needed": "Resting DBP versus patient-important outcomes", "role": "Required", "role_reason": "This condition connects Resting DBP versus patient-important outcomes with selected resting diastolic pressure, key null versus separate supportive results, and measurement, denominator, duration, comparator, support and harm boundaries.", "application_exception": "Preserve selected subclaim D and the key null between-group note. Distinguish absent subclaim score/status/axes from parent grade C with 54 points. A null result does not establish an effect of 0 or equivalence; SBP values are not transferred to DBP. Create no new effects, CIs, totals, grades, independence/safety certification or exercise, breathing, medication or treatment instructions.", "criterion": "Material for Resting DBP versus patient-important outcomes must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.", "basis": "Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.", "condition_origin": "Internally applied conditions preserved for the existing subclaim. They do not establish preregistration, official-tool certification or completed content review.", "proposed_research": "Material needed: DBP clinical-importance thresholds and separate event/medication comparisons are needed. Create no event-prevention or treatment-replacement conclusion. This records needed materials; no new research was executed." }, { "item_id": "N15", "question_type": "Evidence condition", "question": "Are shared reports being counted as new trials?", "needed": "Reports, trials, selected questions and shared samples", "role": "Required", "role_reason": "This condition connects Reports, trials, selected questions and shared samples with selected resting diastolic pressure, key null versus separate supportive results, and measurement, denominator, duration, comparator, support and harm boundaries.", "application_exception": "Preserve selected subclaim D and the key null between-group note. Distinguish absent subclaim score/status/axes from parent grade C with 54 points. A null result does not establish an effect of 0 or equivalence; SBP values are not transferred to DBP. Create no new effects, CIs, totals, grades, independence/safety certification or exercise, breathing, medication or treatment instructions.", "criterion": "Material for Reports, trials, selected questions and shared samples must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.", "basis": "Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.", "condition_origin": "Internally applied conditions preserved for the existing subclaim. They do not establish preregistration, official-tool certification or completed content review.", "proposed_research": "Material needed: Report, cohort and analysis-population identity and overlap material are needed. No new unique totals or independent-replication certification are created. This records needed materials; no new research was executed." }, { "item_id": "N16", "question_type": "Evidence condition", "question": "Which materials were actually read?", "needed": "Stored summaries versus external access", "role": "Required", "role_reason": "This condition connects Stored summaries versus external access with selected resting diastolic pressure, key null versus separate supportive results, and measurement, denominator, duration, comparator, support and harm boundaries.", "application_exception": "Preserve selected subclaim D and the key null between-group note. Distinguish absent subclaim score/status/axes from parent grade C with 54 points. A null result does not establish an effect of 0 or equivalence; SBP values are not transferred to DBP. Create no new effects, CIs, totals, grades, independence/safety certification or exercise, breathing, medication or treatment instructions.", "criterion": "Material for Stored summaries versus external access must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.", "basis": "Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.", "condition_origin": "Internally applied conditions preserved for the existing subclaim. They do not establish preregistration, official-tool certification or completed content review.", "proposed_research": "Material needed: Actual originals, appendices and access records are needed. URLs or historical verification do not establish current reading or fulfillment. This records needed materials; no new research was executed." }, { "item_id": "N17", "question_type": "Evidence condition", "question": "Where are bibliographies and registration identifiers recorded?", "needed": "Report-specific bibliography and identifier locations", "role": "Required", "role_reason": "This condition connects Report-specific bibliography and identifier locations with selected resting diastolic pressure, key null versus separate supportive results, and measurement, denominator, duration, comparator, support and harm boundaries.", "application_exception": "Preserve selected subclaim D and the key null between-group note. Distinguish absent subclaim score/status/axes from parent grade C with 54 points. A null result does not establish an effect of 0 or equivalence; SBP values are not transferred to DBP. Create no new effects, CIs, totals, grades, independence/safety certification or exercise, breathing, medication or treatment instructions.", "criterion": "Material for Report-specific bibliography and identifier locations must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.", "basis": "Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.", "condition_origin": "Internally applied conditions preserved for the existing subclaim. They do not establish preregistration, official-tool certification or completed content review.", "proposed_research": "Material needed: Original-paper/registration identity, dates and links are needed. Infer no new URL from identifiers or actual registration reading. This records needed materials; no new research was executed." }, { "item_id": "N18", "question_type": "Evidence condition", "question": "How are both languages and historical checks preserved?", "needed": "Both languages, selected note and historical scope", "role": "Required", "role_reason": "This condition connects Both languages, selected note and historical scope with selected resting diastolic pressure, key null versus separate supportive results, and measurement, denominator, duration, comparator, support and harm boundaries.", "application_exception": "Preserve selected subclaim D and the key null between-group note. Distinguish absent subclaim score/status/axes from parent grade C with 54 points. A null result does not establish an effect of 0 or equivalence; SBP values are not transferred to DBP. Create no new effects, CIs, totals, grades, independence/safety certification or exercise, breathing, medication or treatment instructions.", "criterion": "Material for Both languages, selected note and historical scope must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.", "basis": "Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.", "condition_origin": "Internally applied conditions preserved for the existing subclaim. They do not establish preregistration, official-tool certification or completed content review.", "proposed_research": "Material needed: Original text, translation and correction review are needed. Historical verification is not a current clinical-review pass. This records needed materials; no new research was executed." }, { "item_id": "N19", "question_type": "Evidence condition", "question": "Are subclaim values distinct from parent grades/axes?", "needed": "Original subclaim grade/note and absent values versus parent context", "role": "Required", "role_reason": "This condition connects Original subclaim grade/note and absent values versus parent context with selected resting diastolic pressure, key null versus separate supportive results, and measurement, denominator, duration, comparator, support and harm boundaries.", "application_exception": "Preserve selected subclaim D and the key null between-group note. Distinguish absent subclaim score/status/axes from parent grade C with 54 points. A null result does not establish an effect of 0 or equivalence; SBP values are not transferred to DBP. Create no new effects, CIs, totals, grades, independence/safety certification or exercise, breathing, medication or treatment instructions.", "criterion": "Material for Original subclaim grade/note and absent values versus parent context must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.", "basis": "Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.", "condition_origin": "Internally applied conditions preserved for the existing subclaim. They do not establish preregistration, official-tool certification or completed content review.", "proposed_research": "Material needed: Selected-question boundary/content review is needed. Do not rescore, revise axes or copy the parent score. This records needed materials; no new research was executed." }, { "item_id": "N20", "question_type": "Evidence condition", "question": "What are the evidence date and correction records?", "needed": "Original date/empty records versus production date", "role": "Required", "role_reason": "This condition connects Original date/empty records versus production date with selected resting diastolic pressure, key null versus separate supportive results, and measurement, denominator, duration, comparator, support and harm boundaries.", "application_exception": "Preserve selected subclaim D and the key null between-group note. Distinguish absent subclaim score/status/axes from parent grade C with 54 points. A null result does not establish an effect of 0 or equivalence; SBP values are not transferred to DBP. Create no new effects, CIs, totals, grades, independence/safety certification or exercise, breathing, medication or treatment instructions.", "criterion": "Material for Original date/empty records versus production date must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.", "basis": "Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.", "condition_origin": "Internally applied conditions preserved for the existing subclaim. They do not establish preregistration, official-tool certification or completed content review.", "proposed_research": "Material needed: Current corrections, follow-up material and source history are needed. Do not inject new dates, corrections or verdict values. This records needed materials; no new research was executed." }, { "item_id": "N21", "question_type": "Evidence condition", "question": "Are funding, support, employed authors and analysis roles distinct?", "needed": "Report-specific funding and company involvement", "role": "Required", "role_reason": "This condition connects Report-specific funding and company involvement with selected resting diastolic pressure, key null versus separate supportive results, and measurement, denominator, duration, comparator, support and harm boundaries.", "application_exception": "Preserve selected subclaim D and the key null between-group note. Distinguish absent subclaim score/status/axes from parent grade C with 54 points. A null result does not establish an effect of 0 or equivalence; SBP values are not transferred to DBP. Create no new effects, CIs, totals, grades, independence/safety certification or exercise, breathing, medication or treatment instructions.", "criterion": "Material for Report-specific funding and company involvement must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.", "basis": "Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.", "condition_origin": "Internally applied conditions preserved for the existing subclaim. They do not establish preregistration, official-tool certification or completed content review.", "proposed_research": "Material needed: Original funding, support, affiliations and analysis/publication roles are needed. Missing information is not no company involvement; parent I2 is not newly certified. This records needed materials; no new research was executed." }, { "item_id": "N22", "question_type": "Evidence condition", "question": "Are allocation, blinding and measurement-bias materials verified?", "needed": "Allocation, measurement and selective reporting", "role": "Required", "role_reason": "This condition connects Allocation, measurement and selective reporting with selected resting diastolic pressure, key null versus separate supportive results, and measurement, denominator, duration, comparator, support and harm boundaries.", "application_exception": "Preserve selected subclaim D and the key null between-group note. Distinguish absent subclaim score/status/axes from parent grade C with 54 points. A null result does not establish an effect of 0 or equivalence; SBP values are not transferred to DBP. Create no new effects, CIs, totals, grades, independence/safety certification or exercise, breathing, medication or treatment instructions.", "criterion": "Material for Allocation, measurement and selective reporting must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.", "basis": "Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.", "condition_origin": "Internally applied conditions preserved for the existing subclaim. They do not establish preregistration, official-tool certification or completed content review.", "proposed_research": "Material needed: Methods, protocols/SAPs, measurements and change history are needed. Design names alone do not establish official appraisal or completed clinical review. This records needed materials; no new research was executed." }, { "item_id": "N23", "question_type": "Evidence condition", "question": "Is delivery context distinct from actual exposure?", "needed": "Intervention identity, adherence and cointerventions", "role": "Required", "role_reason": "This condition connects Intervention identity, adherence and cointerventions with selected resting diastolic pressure, key null versus separate supportive results, and measurement, denominator, duration, comparator, support and harm boundaries.", "application_exception": "Preserve selected subclaim D and the key null between-group note. Distinguish absent subclaim score/status/axes from parent grade C with 54 points. A null result does not establish an effect of 0 or equivalence; SBP values are not transferred to DBP. Create no new effects, CIs, totals, grades, independence/safety certification or exercise, breathing, medication or treatment instructions.", "criterion": "Material for Intervention identity, adherence and cointerventions must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.", "basis": "Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.", "condition_origin": "Internally applied conditions preserved for the existing subclaim. They do not establish preregistration, official-tool certification or completed content review.", "proposed_research": "Material needed: Arm exposure, deviations, cointerventions and analysis impact are needed. Create no exposure total, procedure, intensity-calibration method or medication-change instructions. This records needed materials; no new research was executed." }, { "item_id": "N24", "question_type": "Evidence condition", "question": "Are acute in-exercise and resting pressure the same?", "needed": "Acute timing and separate-report identity", "role": "Supplementary", "role_reason": "This condition connects Acute timing and separate-report identity with selected resting diastolic pressure, key null versus separate supportive results, and measurement, denominator, duration, comparator, support and harm boundaries.", "application_exception": "Preserve selected subclaim D and the key null between-group note. Distinguish absent subclaim score/status/axes from parent grade C with 54 points. A null result does not establish an effect of 0 or equivalence; SBP values are not transferred to DBP. Create no new effects, CIs, totals, grades, independence/safety certification or exercise, breathing, medication or treatment instructions.", "criterion": "Material for Acute timing and separate-report identity must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.", "basis": "Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.", "condition_origin": "Internally applied conditions preserved for the existing subclaim. They do not establish preregistration, official-tool certification or completed content review.", "proposed_research": "Material needed: Acute originals, populations/denominators, times, exposure and resting-result links are needed. Create no long-term harm rate, event-prevention effect or exercise method from acute values. This records needed materials; no new research was executed." }, { "item_id": "N25", "question_type": "Evidence condition", "question": "What is the scope of 0 reported adverse events?", "needed": "Harm definitions, collection, exposure and arm denominators", "role": "Supplementary", "role_reason": "This condition connects Harm definitions, collection, exposure and arm denominators with selected resting diastolic pressure, key null versus separate supportive results, and measurement, denominator, duration, comparator, support and harm boundaries.", "application_exception": "Preserve selected subclaim D and the key null between-group note. Distinguish absent subclaim score/status/axes from parent grade C with 54 points. A null result does not establish an effect of 0 or equivalence; SBP values are not transferred to DBP. Create no new effects, CIs, totals, grades, independence/safety certification or exercise, breathing, medication or treatment instructions.", "criterion": "Material for Harm definitions, collection, exposure and arm denominators must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.", "basis": "Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.", "condition_origin": "Internally applied conditions preserved for the existing subclaim. They do not establish preregistration, official-tool certification or completed content review.", "proposed_research": "Material needed: Definitions, collection, exposure/denominators, deviations and severity tables are needed. 0 is not complete safety or no harms. This records needed materials; no new research was executed." }, { "item_id": "N26", "question_type": "Evidence condition", "question": "Are long-term/rare harms and post-training effects known?", "needed": "Short-term/maintenance versus long-term harms and clinical boundaries", "role": "Supplementary", "role_reason": "This condition connects Short-term/maintenance versus long-term harms and clinical boundaries with selected resting diastolic pressure, key null versus separate supportive results, and measurement, denominator, duration, comparator, support and harm boundaries.", "application_exception": "Preserve selected subclaim D and the key null between-group note. Distinguish absent subclaim score/status/axes from parent grade C with 54 points. A null result does not establish an effect of 0 or equivalence; SBP values are not transferred to DBP. Create no new effects, CIs, totals, grades, independence/safety certification or exercise, breathing, medication or treatment instructions.", "criterion": "Material for Short-term/maintenance versus long-term harms and clinical boundaries must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.", "basis": "Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.", "condition_origin": "Internally applied conditions preserved for the existing subclaim. They do not establish preregistration, official-tool certification or completed content review.", "proposed_research": "Material needed: Long-term follow-up, surveillance, endpoint denominators and matched interventions/populations are needed. Short-term reports or caution status do not create long-term safety/efficacy certification. This records needed materials; no new research was executed." }, { "item_id": "N27", "question_type": "Evidence condition", "question": "Which materials would trigger an update?", "needed": "Original material, conditions, observations and verdict changes", "role": "Required", "role_reason": "This condition connects Original material, conditions, observations and verdict changes with selected resting diastolic pressure, key null versus separate supportive results, and measurement, denominator, duration, comparator, support and harm boundaries.", "application_exception": "Preserve selected subclaim D and the key null between-group note. Distinguish absent subclaim score/status/axes from parent grade C with 54 points. A null result does not establish an effect of 0 or equivalence; SBP values are not transferred to DBP. Create no new effects, CIs, totals, grades, independence/safety certification or exercise, breathing, medication or treatment instructions.", "criterion": "Material for Original material, conditions, observations and verdict changes must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.", "basis": "Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.", "condition_origin": "Internally applied conditions preserved for the existing subclaim. They do not establish preregistration, official-tool certification or completed content review.", "proposed_research": "Material needed: New original material, complete prechange preservation, criteria versions, applied changes and review history are needed. Create no new clinical research, calculation, verdict or exercise/medication/treatment instructions. This records needed materials; no new research was executed." } ] }