{ "schema_version": "chamgap-public-criteria-1.0", "title": "Vigorous stair exercise snacks × six-week cardiorespiratory fitness", "language": "en", "translation_date": "2026-10-16", "criteria_version": "1.0", "criteria_date": "2026-10-06", "condition_origin": "Chamgap's own application conditions", "method_sources": [ { "id": "M03", "version": "Cochrane Handbook 6.5 (2024), chapter updated 2023-08", "url": "https://www.cochrane.org/authors/handbooks-and-manuals/handbook/current/chapter-03", "section": "§3.1, §3.2.1–3.2.3, MECIR C5/C7/C13", "official_principle": "Clearly record the question, eligibility conditions and reasons for changes, and distinguish variations in interventions.", "review_level": "Existing methodological links were reused for production. External originals were not reread and methodological content was not reassessed." }, { "id": "M04", "version": "Cochrane Handbook 6.5.1 (2025), chapter updated 2025-03", "url": "https://www.cochrane.org/authors/handbooks-and-manuals/handbook/current/chapter-04", "section": "§4.5, §4.6.1–4.6.3, MECIR C42", "official_principle": "Distinguish studies from reports and link them; do not omit a study solely because results are unreported.", "review_level": "Existing methodological links were reused for production. External originals were not reread and methodological content was not reassessed." }, { "id": "M08", "version": "Cochrane Handbook 6.5 (2024), chapter updated 2019-10", "url": "https://www.cochrane.org/authors/handbooks-and-manuals/handbook/current/chapter-08", "section": "§8.1–8.2.3, Table 8.2.a", "official_principle": "Define the outcome and effect of interest, then examine randomization, deviations, missing data, measurement and selective reporting.", "review_level": "Existing methodological links were reused for production. External originals were not reread and methodological content was not reassessed." }, { "id": "M15", "version": "Cochrane Handbook 6.5 (2024), chapter updated 2023-08", "url": "https://www.cochrane.org/authors/handbooks-and-manuals/handbook/current/chapter-15", "section": "§15.2.4, §15.3.1–15.3.3", "official_principle": "Distinguish effect estimates, intervals, importance and applicability. Sample size alone does not determine precision.", "review_level": "Existing methodological links were reused for production. External originals were not reread and methodological content was not reassessed." }, { "id": "M19", "version": "Cochrane Handbook 6.5 (2024), chapter updated 2019-10", "url": "https://www.cochrane.org/authors/handbooks-and-manuals/handbook/current/chapter-19", "section": "§19.1.2, §19.2.1–19.2.4", "official_principle": "Harm questions may require different designs, populations and follow-up from efficacy questions. Case reports do not establish incidence rates.", "review_level": "Existing methodological links were reused for production. External originals were not reread and methodological content was not reassessed." } ], "status_dictionary": { "Met": "A state used when required evidence is confirmed after user review. This production does not declare that review complete.", "Partly verified": "Some information in the stored summary is linked into the table. External comparison/content review is not complete.", "Unverified": "The article leaves this unverified, or required material is absent from the current stored summary. This is distinct from zero, absence or safety.", "Review incomplete": "User review pending.", "Not reported": "Not reported within the stored material actually read; not extended to the entire primary paper.", "Inaccessible": "Means an actual access failure. Access not attempted here is not assigned this state.", "Not applicable": "Not used as a substitute for an evidence gap.", "Conflicting data": "Requires an observed disagreement under the same comparison criteria; not automatically judged in this production.", "Insufficient evidence for the conditions": "Marks a gap in additional material required by the selected conditions; not a new efficacy grade." }, "requirements": [ { "item_id": "N01", "question_type": "Evidence condition", "question": "Which 6-week fitness claim is being checked?", "needed": "Selected subclaim wording, original grade/note and parent context", "role": "Required", "role_reason": "This condition connects Selected subclaim wording, original grade/note and parent context with the 6-week fitness question, inactive young adults, stair training versus no training, VO2peak, missing between-group effects/CIs, acute metabolic background, report-specific support and harms.", "application_exception": "Preserve original exposure/numbers, selected grade C and absent subclaim score, safety and axes. Distinguish P=.003, the approximately 5% description and missing exact between-group effects/CIs. S01 6-week fitness and S02 9-hour acute metabolism use different protocols, populations, comparators and endpoints. No new effects, CIs, exposure/participant/trial totals, independence certification, grades, exercise instructions, medication changes or treatment guidance are created.", "criterion": "Material for Selected subclaim wording, original grade/note and parent context must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.", "basis": "Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.", "condition_origin": "Internally applied conditions preserved for the existing subclaim. They do not establish preregistration, official-tool certification or completed content review.", "proposed_research": "Material needed: The original selected-subclaim version and claim-boundary/editorial review records. This records needed materials; no new research was executed." }, { "item_id": "N02", "question_type": "Evidence condition", "question": "Who was studied and what was the allocation size?", "needed": "Eligibility and group-specific allocation, completion and analysis denominators", "role": "Required", "role_reason": "This condition connects Eligibility and group-specific allocation, completion and analysis denominators with the 6-week fitness question, inactive young adults, stair training versus no training, VO2peak, missing between-group effects/CIs, acute metabolic background, report-specific support and harms.", "application_exception": "Preserve original exposure/numbers, selected grade C and absent subclaim score, safety and axes. Distinguish P=.003, the approximately 5% description and missing exact between-group effects/CIs. S01 6-week fitness and S02 9-hour acute metabolism use different protocols, populations, comparators and endpoints. No new effects, CIs, exposure/participant/trial totals, independence certification, grades, exercise instructions, medication changes or treatment guidance are created.", "criterion": "Material for Eligibility and group-specific allocation, completion and analysis denominators must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.", "basis": "Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.", "condition_origin": "Internally applied conditions preserved for the existing subclaim. They do not establish preregistration, official-tool certification or completed content review.", "proposed_research": "Material needed: S01 eligibility, baseline-characteristics table, participant flow and group-specific completion/analysis denominators. This records needed materials; no new research was executed." }, { "item_id": "N03", "question_type": "Evidence condition", "question": "What was the original 6-week intervention exposure?", "needed": "Research intervention, planned exposure and actual performance", "role": "Required", "role_reason": "This condition connects Research intervention, planned exposure and actual performance with the 6-week fitness question, inactive young adults, stair training versus no training, VO2peak, missing between-group effects/CIs, acute metabolic background, report-specific support and harms.", "application_exception": "Preserve original exposure/numbers, selected grade C and absent subclaim score, safety and axes. Distinguish P=.003, the approximately 5% description and missing exact between-group effects/CIs. S01 6-week fitness and S02 9-hour acute metabolism use different protocols, populations, comparators and endpoints. No new effects, CIs, exposure/participant/trial totals, independence certification, grades, exercise instructions, medication changes or treatment guidance are created.", "criterion": "Material for Research intervention, planned exposure and actual performance must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.", "basis": "Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.", "condition_origin": "Internally applied conditions preserved for the existing subclaim. They do not establish preregistration, official-tool certification or completed content review.", "proposed_research": "Material needed: S01 intervention specifications, performance records, appendices and actual intensity/supervision materials. This records needed materials; no new research was executed." }, { "item_id": "N04", "question_type": "Evidence condition", "question": "What does the no-training comparison represent?", "needed": "Control activity, contact and expectancy differences", "role": "Required", "role_reason": "This condition connects Control activity, contact and expectancy differences with the 6-week fitness question, inactive young adults, stair training versus no training, VO2peak, missing between-group effects/CIs, acute metabolic background, report-specific support and harms.", "application_exception": "Preserve original exposure/numbers, selected grade C and absent subclaim score, safety and axes. Distinguish P=.003, the approximately 5% description and missing exact between-group effects/CIs. S01 6-week fitness and S02 9-hour acute metabolism use different protocols, populations, comparators and endpoints. No new effects, CIs, exposure/participant/trial totals, independence certification, grades, exercise instructions, medication changes or treatment guidance are created.", "criterion": "Material for Control activity, contact and expectancy differences must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.", "basis": "Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.", "condition_origin": "Internally applied conditions preserved for the existing subclaim. They do not establish preregistration, official-tool certification or completed content review.", "proposed_research": "Material needed: S01 control-management, activity-measurement, contact and expectancy-difference records. This records needed materials; no new research was executed." }, { "item_id": "N05", "question_type": "Evidence condition", "question": "Is the randomization process verified?", "needed": "Allocation generation, concealment and recruitment order", "role": "Required", "role_reason": "This condition connects Allocation generation, concealment and recruitment order with the 6-week fitness question, inactive young adults, stair training versus no training, VO2peak, missing between-group effects/CIs, acute metabolic background, report-specific support and harms.", "application_exception": "Preserve original exposure/numbers, selected grade C and absent subclaim score, safety and axes. Distinguish P=.003, the approximately 5% description and missing exact between-group effects/CIs. S01 6-week fitness and S02 9-hour acute metabolism use different protocols, populations, comparators and endpoints. No new effects, CIs, exposure/participant/trial totals, independence certification, grades, exercise instructions, medication changes or treatment guidance are created.", "criterion": "Material for Allocation generation, concealment and recruitment order must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.", "basis": "Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.", "condition_origin": "Internally applied conditions preserved for the existing subclaim. They do not establish preregistration, official-tool certification or completed content review.", "proposed_research": "Material needed: S01 original methods, allocation procedures, recruitment order and research plans. This records needed materials; no new research was executed." }, { "item_id": "N06", "question_type": "Evidence condition", "question": "Does an objective fitness endpoint establish blinding?", "needed": "Assessor/analyst blinding and test conditions", "role": "Required", "role_reason": "This condition connects Assessor/analyst blinding and test conditions with the 6-week fitness question, inactive young adults, stair training versus no training, VO2peak, missing between-group effects/CIs, acute metabolic background, report-specific support and harms.", "application_exception": "Preserve original exposure/numbers, selected grade C and absent subclaim score, safety and axes. Distinguish P=.003, the approximately 5% description and missing exact between-group effects/CIs. S01 6-week fitness and S02 9-hour acute metabolism use different protocols, populations, comparators and endpoints. No new effects, CIs, exposure/participant/trial totals, independence certification, grades, exercise instructions, medication changes or treatment guidance are created.", "criterion": "Material for Assessor/analyst blinding and test conditions must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.", "basis": "Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.", "condition_origin": "Internally applied conditions preserved for the existing subclaim. They do not establish preregistration, official-tool certification or completed content review.", "proposed_research": "Material needed: S01 assessor/analyst blinding records and test procedures. This records needed materials; no new research was executed." }, { "item_id": "N07", "question_type": "Evidence condition", "question": "What defines VO2peak, its units and test method?", "needed": "Endpoint definition, equipment, units and measurement timing", "role": "Required", "role_reason": "This condition connects Endpoint definition, equipment, units and measurement timing with the 6-week fitness question, inactive young adults, stair training versus no training, VO2peak, missing between-group effects/CIs, acute metabolic background, report-specific support and harms.", "application_exception": "Preserve original exposure/numbers, selected grade C and absent subclaim score, safety and axes. Distinguish P=.003, the approximately 5% description and missing exact between-group effects/CIs. S01 6-week fitness and S02 9-hour acute metabolism use different protocols, populations, comparators and endpoints. No new effects, CIs, exposure/participant/trial totals, independence certification, grades, exercise instructions, medication changes or treatment guidance are created.", "criterion": "Material for Endpoint definition, equipment, units and measurement timing must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.", "basis": "Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.", "condition_origin": "Internally applied conditions preserved for the existing subclaim. They do not establish preregistration, official-tool certification or completed content review.", "proposed_research": "Material needed: S01 endpoint definition, test procedures, equipment, units, measurement timing and result tables. This records needed materials; no new research was executed." }, { "item_id": "N08", "question_type": "Evidence condition", "question": "Are between-group P and approximately 5% wording the same effect?", "needed": "Test target and attribution of described change", "role": "Required", "role_reason": "This condition connects Test target and attribution of described change with the 6-week fitness question, inactive young adults, stair training versus no training, VO2peak, missing between-group effects/CIs, acute metabolic background, report-specific support and harms.", "application_exception": "Preserve original exposure/numbers, selected grade C and absent subclaim score, safety and axes. Distinguish P=.003, the approximately 5% description and missing exact between-group effects/CIs. S01 6-week fitness and S02 9-hour acute metabolism use different protocols, populations, comparators and endpoints. No new effects, CIs, exposure/participant/trial totals, independence certification, grades, exercise instructions, medication changes or treatment guidance are created.", "criterion": "Material for Test target and attribution of described change must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.", "basis": "Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.", "condition_origin": "Internally applied conditions preserved for the existing subclaim. They do not establish preregistration, official-tool certification or completed content review.", "proposed_research": "Material needed: S01 group-specific original values, changes, between-group analysis tables and attribution of each described value. This records needed materials; no new research was executed." }, { "item_id": "N09", "question_type": "Evidence condition", "question": "Are the exact comparative effect and 95% CI available?", "needed": "Comparative estimator, effect and uncertainty", "role": "Required", "role_reason": "This condition connects Comparative estimator, effect and uncertainty with the 6-week fitness question, inactive young adults, stair training versus no training, VO2peak, missing between-group effects/CIs, acute metabolic background, report-specific support and harms.", "application_exception": "Preserve original exposure/numbers, selected grade C and absent subclaim score, safety and axes. Distinguish P=.003, the approximately 5% description and missing exact between-group effects/CIs. S01 6-week fitness and S02 9-hour acute metabolism use different protocols, populations, comparators and endpoints. No new effects, CIs, exposure/participant/trial totals, independence certification, grades, exercise instructions, medication changes or treatment guidance are created.", "criterion": "Material for Comparative estimator, effect and uncertainty must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.", "basis": "Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.", "condition_origin": "Internally applied conditions preserved for the existing subclaim. They do not establish preregistration, official-tool certification or completed content review.", "proposed_research": "Material needed: S01 between-group analysis tables, estimation models, exact effects and direct CIs. This records needed materials; no new research was executed." }, { "item_id": "N10", "question_type": "Evidence condition", "question": "Is the practical size of the fitness signal known?", "needed": "Effect magnitude, measurement error and relevance criteria", "role": "Required", "role_reason": "This condition connects Effect magnitude, measurement error and relevance criteria with the 6-week fitness question, inactive young adults, stair training versus no training, VO2peak, missing between-group effects/CIs, acute metabolic background, report-specific support and harms.", "application_exception": "Preserve original exposure/numbers, selected grade C and absent subclaim score, safety and axes. Distinguish P=.003, the approximately 5% description and missing exact between-group effects/CIs. S01 6-week fitness and S02 9-hour acute metabolism use different protocols, populations, comparators and endpoints. No new effects, CIs, exposure/participant/trial totals, independence certification, grades, exercise instructions, medication changes or treatment guidance are created.", "criterion": "Material for Effect magnitude, measurement error and relevance criteria must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.", "basis": "Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.", "condition_origin": "Internally applied conditions preserved for the existing subclaim. They do not establish preregistration, official-tool certification or completed content review.", "proposed_research": "Material needed: S01 effect distributions, measurement error and practical/clinical relevance criteria. This records needed materials; no new research was executed." }, { "item_id": "N11", "question_type": "Evidence condition", "question": "Are 24 participants the completion/analysis denominator?", "needed": "Allocation, completion, endpoint-specific analysis and missing data", "role": "Required", "role_reason": "This condition connects Allocation, completion, endpoint-specific analysis and missing data with the 6-week fitness question, inactive young adults, stair training versus no training, VO2peak, missing between-group effects/CIs, acute metabolic background, report-specific support and harms.", "application_exception": "Preserve original exposure/numbers, selected grade C and absent subclaim score, safety and axes. Distinguish P=.003, the approximately 5% description and missing exact between-group effects/CIs. S01 6-week fitness and S02 9-hour acute metabolism use different protocols, populations, comparators and endpoints. No new effects, CIs, exposure/participant/trial totals, independence certification, grades, exercise instructions, medication changes or treatment guidance are created.", "criterion": "Material for Allocation, completion, endpoint-specific analysis and missing data must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.", "basis": "Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.", "condition_origin": "Internally applied conditions preserved for the existing subclaim. They do not establish preregistration, official-tool certification or completed content review.", "proposed_research": "Material needed: S01 participant flow, group-specific missing-data reasons, analysis-population definitions and endpoint denominators. This records needed materials; no new research was executed." }, { "item_id": "N12", "question_type": "Evidence condition", "question": "Does planned exposure equal actual adherence?", "needed": "Actual performance, discontinuation and exposure variation", "role": "Required", "role_reason": "This condition connects Actual performance, discontinuation and exposure variation with the 6-week fitness question, inactive young adults, stair training versus no training, VO2peak, missing between-group effects/CIs, acute metabolic background, report-specific support and harms.", "application_exception": "Preserve original exposure/numbers, selected grade C and absent subclaim score, safety and axes. Distinguish P=.003, the approximately 5% description and missing exact between-group effects/CIs. S01 6-week fitness and S02 9-hour acute metabolism use different protocols, populations, comparators and endpoints. No new effects, CIs, exposure/participant/trial totals, independence certification, grades, exercise instructions, medication changes or treatment guidance are created.", "criterion": "Material for Actual performance, discontinuation and exposure variation must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.", "basis": "Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.", "condition_origin": "Internally applied conditions preserved for the existing subclaim. They do not establish preregistration, official-tool certification or completed content review.", "proposed_research": "Material needed: S01 adherence, discontinuation, exposure-variation and activity-monitoring records. This records needed materials; no new research was executed." }, { "item_id": "N13", "question_type": "Evidence condition", "question": "Are concurrent activity and lifestyle changes separated?", "needed": "Other exercise, daily activity and group-specific lifestyle changes", "role": "Required", "role_reason": "This condition connects Other exercise, daily activity and group-specific lifestyle changes with the 6-week fitness question, inactive young adults, stair training versus no training, VO2peak, missing between-group effects/CIs, acute metabolic background, report-specific support and harms.", "application_exception": "Preserve original exposure/numbers, selected grade C and absent subclaim score, safety and axes. Distinguish P=.003, the approximately 5% description and missing exact between-group effects/CIs. S01 6-week fitness and S02 9-hour acute metabolism use different protocols, populations, comparators and endpoints. No new effects, CIs, exposure/participant/trial totals, independence certification, grades, exercise instructions, medication changes or treatment guidance are created.", "criterion": "Material for Other exercise, daily activity and group-specific lifestyle changes must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.", "basis": "Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.", "condition_origin": "Internally applied conditions preserved for the existing subclaim. They do not establish preregistration, official-tool certification or completed content review.", "proposed_research": "Material needed: S01 concurrent activity, lifestyle changes, baseline covariates and adjustment plans. This records needed materials; no new research was executed." }, { "item_id": "N14", "question_type": "Evidence condition", "question": "Are prespecified endpoints, registration and plans verified?", "needed": "Registration, protocols, SAPs and endpoint hierarchy", "role": "Required", "role_reason": "This condition connects Registration, protocols, SAPs and endpoint hierarchy with the 6-week fitness question, inactive young adults, stair training versus no training, VO2peak, missing between-group effects/CIs, acute metabolic background, report-specific support and harms.", "application_exception": "Preserve original exposure/numbers, selected grade C and absent subclaim score, safety and axes. Distinguish P=.003, the approximately 5% description and missing exact between-group effects/CIs. S01 6-week fitness and S02 9-hour acute metabolism use different protocols, populations, comparators and endpoints. No new effects, CIs, exposure/participant/trial totals, independence certification, grades, exercise instructions, medication changes or treatment guidance are created.", "criterion": "Material for Registration, protocols, SAPs and endpoint hierarchy must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.", "basis": "Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.", "condition_origin": "Internally applied conditions preserved for the existing subclaim. They do not establish preregistration, official-tool certification or completed content review.", "proposed_research": "Material needed: S01 original registration, protocols, SAPs, change history and actual endpoint hierarchy. This records needed materials; no new research was executed." }, { "item_id": "N15", "question_type": "Evidence condition", "question": "Are analysis models and multiplicity plans available?", "needed": "Between-group tests, adjustment variables and multiple comparisons", "role": "Required", "role_reason": "This condition connects Between-group tests, adjustment variables and multiple comparisons with the 6-week fitness question, inactive young adults, stair training versus no training, VO2peak, missing between-group effects/CIs, acute metabolic background, report-specific support and harms.", "application_exception": "Preserve original exposure/numbers, selected grade C and absent subclaim score, safety and axes. Distinguish P=.003, the approximately 5% description and missing exact between-group effects/CIs. S01 6-week fitness and S02 9-hour acute metabolism use different protocols, populations, comparators and endpoints. No new effects, CIs, exposure/participant/trial totals, independence certification, grades, exercise instructions, medication changes or treatment guidance are created.", "criterion": "Material for Between-group tests, adjustment variables and multiple comparisons must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.", "basis": "Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.", "condition_origin": "Internally applied conditions preserved for the existing subclaim. They do not establish preregistration, official-tool certification or completed content review.", "proposed_research": "Material needed: S01 SAP, complete endpoint-analysis tables, between-group models and prespecified multiplicity plans. This records needed materials; no new research was executed." }, { "item_id": "N16", "question_type": "Evidence condition", "question": "Is the acute metabolic protocol the same?", "needed": "Separating 6-week training from acute exposure, comparator and duration", "role": "Required", "role_reason": "This condition connects Separating 6-week training from acute exposure, comparator and duration with the 6-week fitness question, inactive young adults, stair training versus no training, VO2peak, missing between-group effects/CIs, acute metabolic background, report-specific support and harms.", "application_exception": "Preserve original exposure/numbers, selected grade C and absent subclaim score, safety and axes. Distinguish P=.003, the approximately 5% description and missing exact between-group effects/CIs. S01 6-week fitness and S02 9-hour acute metabolism use different protocols, populations, comparators and endpoints. No new effects, CIs, exposure/participant/trial totals, independence certification, grades, exercise instructions, medication changes or treatment guidance are created.", "criterion": "Material for Separating 6-week training from acute exposure, comparator and duration must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.", "basis": "Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.", "condition_origin": "Internally applied conditions preserved for the existing subclaim. They do not establish preregistration, official-tool certification or completed content review.", "proposed_research": "Material needed: S02 complete intervention, comparator, duration, actual-exposure and endpoint tables. This records needed materials; no new research was executed." }, { "item_id": "N17", "question_type": "Evidence condition", "question": "How do the two experiments in S02 relate?", "needed": "Report, experiments and population-specific correspondence", "role": "Required", "role_reason": "This condition connects Report, experiments and population-specific correspondence with the 6-week fitness question, inactive young adults, stair training versus no training, VO2peak, missing between-group effects/CIs, acute metabolic background, report-specific support and harms.", "application_exception": "Preserve original exposure/numbers, selected grade C and absent subclaim score, safety and axes. Distinguish P=.003, the approximately 5% description and missing exact between-group effects/CIs. S01 6-week fitness and S02 9-hour acute metabolism use different protocols, populations, comparators and endpoints. No new effects, CIs, exposure/participant/trial totals, independence certification, grades, exercise instructions, medication changes or treatment guidance are created.", "criterion": "Material for Report, experiments and population-specific correspondence must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.", "basis": "Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.", "condition_origin": "Internally applied conditions preserved for the existing subclaim. They do not establish preregistration, official-tool certification or completed content review.", "proposed_research": "Material needed: S02 experiment-specific flow, methods, eligibility, analysis denominators and population relationships. This records needed materials; no new research was executed." }, { "item_id": "N18", "question_type": "Evidence condition", "question": "Are acute insulin/glucose findings fitness effects?", "needed": "Separate VO2peak and insulin/glucose AUC outcomes", "role": "Required", "role_reason": "This condition connects Separate VO2peak and insulin/glucose AUC outcomes with the 6-week fitness question, inactive young adults, stair training versus no training, VO2peak, missing between-group effects/CIs, acute metabolic background, report-specific support and harms.", "application_exception": "Preserve original exposure/numbers, selected grade C and absent subclaim score, safety and axes. Distinguish P=.003, the approximately 5% description and missing exact between-group effects/CIs. S01 6-week fitness and S02 9-hour acute metabolism use different protocols, populations, comparators and endpoints. No new effects, CIs, exposure/participant/trial totals, independence certification, grades, exercise instructions, medication changes or treatment guidance are created.", "criterion": "Material for Separate VO2peak and insulin/glucose AUC outcomes must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.", "basis": "Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.", "condition_origin": "Internally applied conditions preserved for the existing subclaim. They do not establish preregistration, official-tool certification or completed content review.", "proposed_research": "Material needed: Original report/population/endpoint results, units, denominators, direct effects/CIs and prespecified analysis plans. This records needed materials; no new research was executed." }, { "item_id": "N19", "question_type": "Evidence condition", "question": "Is independent replication of the same protocol verified?", "needed": "Study families, the same protocol and outcome relationships", "role": "Required", "role_reason": "This condition connects Study families, the same protocol and outcome relationships with the 6-week fitness question, inactive young adults, stair training versus no training, VO2peak, missing between-group effects/CIs, acute metabolic background, report-specific support and harms.", "application_exception": "Preserve original exposure/numbers, selected grade C and absent subclaim score, safety and axes. Distinguish P=.003, the approximately 5% description and missing exact between-group effects/CIs. S01 6-week fitness and S02 9-hour acute metabolism use different protocols, populations, comparators and endpoints. No new effects, CIs, exposure/participant/trial totals, independence certification, grades, exercise instructions, medication changes or treatment guidance are created.", "criterion": "Material for Study families, the same protocol and outcome relationships must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.", "basis": "Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.", "condition_origin": "Internally applied conditions preserved for the existing subclaim. They do not establish preregistration, official-tool certification or completed content review.", "proposed_research": "Material needed: Separate same-protocol trials, researchers, cohorts and study-family relationships. This records needed materials; no new research was executed." }, { "item_id": "N20", "question_type": "Evidence condition", "question": "Do 6-week findings establish persistence or disease prevention?", "needed": "Post-training fitness persistence and clinical endpoints", "role": "Required", "role_reason": "This condition connects Post-training fitness persistence and clinical endpoints with the 6-week fitness question, inactive young adults, stair training versus no training, VO2peak, missing between-group effects/CIs, acute metabolic background, report-specific support and harms.", "application_exception": "Preserve original exposure/numbers, selected grade C and absent subclaim score, safety and axes. Distinguish P=.003, the approximately 5% description and missing exact between-group effects/CIs. S01 6-week fitness and S02 9-hour acute metabolism use different protocols, populations, comparators and endpoints. No new effects, CIs, exposure/participant/trial totals, independence certification, grades, exercise instructions, medication changes or treatment guidance are created.", "criterion": "Material for Post-training fitness persistence and clinical endpoints must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.", "basis": "Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.", "condition_origin": "Internally applied conditions preserved for the existing subclaim. They do not establish preregistration, official-tool certification or completed content review.", "proposed_research": "Material needed: Post-training fitness measurements, sufficient follow-up and direct long-term clinical outcomes. This records needed materials; no new research was executed." }, { "item_id": "N21", "question_type": "Evidence condition", "question": "Does this apply across ages and diseases?", "needed": "Population-specific direct materials and selection boundaries", "role": "Required", "role_reason": "This condition connects Population-specific direct materials and selection boundaries with the 6-week fitness question, inactive young adults, stair training versus no training, VO2peak, missing between-group effects/CIs, acute metabolic background, report-specific support and harms.", "application_exception": "Preserve original exposure/numbers, selected grade C and absent subclaim score, safety and axes. Distinguish P=.003, the approximately 5% description and missing exact between-group effects/CIs. S01 6-week fitness and S02 9-hour acute metabolism use different protocols, populations, comparators and endpoints. No new effects, CIs, exposure/participant/trial totals, independence certification, grades, exercise instructions, medication changes or treatment guidance are created.", "criterion": "Material for Population-specific direct materials and selection boundaries must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.", "basis": "Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.", "condition_origin": "Internally applied conditions preserved for the existing subclaim. They do not establish preregistration, official-tool certification or completed content review.", "proposed_research": "Material needed: Population-specific eligibility, baseline status, subgroup plans and direct endpoint materials. This records needed materials; no new research was executed." }, { "item_id": "N22", "question_type": "Evidence condition", "question": "What are S01 funding, support and interests?", "needed": "Funding, product support, employee authors and COI", "role": "Required", "role_reason": "This condition connects Funding, product support, employee authors and COI with the 6-week fitness question, inactive young adults, stair training versus no training, VO2peak, missing between-group effects/CIs, acute metabolic background, report-specific support and harms.", "application_exception": "Preserve original exposure/numbers, selected grade C and absent subclaim score, safety and axes. Distinguish P=.003, the approximately 5% description and missing exact between-group effects/CIs. S01 6-week fitness and S02 9-hour acute metabolism use different protocols, populations, comparators and endpoints. No new effects, CIs, exposure/participant/trial totals, independence certification, grades, exercise instructions, medication changes or treatment guidance are created.", "criterion": "Material for Funding, product support, employee authors and COI must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.", "basis": "Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.", "condition_origin": "Internally applied conditions preserved for the existing subclaim. They do not establish preregistration, official-tool certification or completed content review.", "proposed_research": "Material needed: S01 original funding, product/equipment support, affiliations, COI and analysis/publication roles. This records needed materials; no new research was executed." }, { "item_id": "N23", "question_type": "Evidence condition", "question": "Is the S02 support gap separate?", "needed": "Report-specific funding, support and interests", "role": "Required", "role_reason": "This condition connects Report-specific funding, support and interests with the 6-week fitness question, inactive young adults, stair training versus no training, VO2peak, missing between-group effects/CIs, acute metabolic background, report-specific support and harms.", "application_exception": "Preserve original exposure/numbers, selected grade C and absent subclaim score, safety and axes. Distinguish P=.003, the approximately 5% description and missing exact between-group effects/CIs. S01 6-week fitness and S02 9-hour acute metabolism use different protocols, populations, comparators and endpoints. No new effects, CIs, exposure/participant/trial totals, independence certification, grades, exercise instructions, medication changes or treatment guidance are created.", "criterion": "Material for Report-specific funding, support and interests must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.", "basis": "Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.", "condition_origin": "Internally applied conditions preserved for the existing subclaim. They do not establish preregistration, official-tool certification or completed content review.", "proposed_research": "Material needed: S02 original funding, product/equipment support, affiliations, COI and analysis/publication roles. This records needed materials; no new research was executed." }, { "item_id": "N24", "question_type": "Evidence condition", "question": "Are systematic safety materials available?", "needed": "Adverse-event collection, exposure, denominators and discontinuation", "role": "Supplementary", "role_reason": "This condition connects Adverse-event collection, exposure, denominators and discontinuation with the 6-week fitness question, inactive young adults, stair training versus no training, VO2peak, missing between-group effects/CIs, acute metabolic background, report-specific support and harms.", "application_exception": "Preserve original exposure/numbers, selected grade C and absent subclaim score, safety and axes. Distinguish P=.003, the approximately 5% description and missing exact between-group effects/CIs. S01 6-week fitness and S02 9-hour acute metabolism use different protocols, populations, comparators and endpoints. No new effects, CIs, exposure/participant/trial totals, independence certification, grades, exercise instructions, medication changes or treatment guidance are created.", "criterion": "Material for Adverse-event collection, exposure, denominators and discontinuation must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.", "basis": "Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.", "condition_origin": "Internally applied conditions preserved for the existing subclaim. They do not establish preregistration, official-tool certification or completed content review.", "proposed_research": "Material needed: Report-specific adverse-event definitions, collection, exposure, denominators, discontinuation, severity and follow-up materials. This records needed materials; no new research was executed." }, { "item_id": "N25", "question_type": "Evidence condition", "question": "Are parent values and historical adjustments separated?", "needed": "Parent/subclaim original values and verdict history", "role": "Required", "role_reason": "This condition connects Parent/subclaim original values and verdict history with the 6-week fitness question, inactive young adults, stair training versus no training, VO2peak, missing between-group effects/CIs, acute metabolic background, report-specific support and harms.", "application_exception": "Preserve original exposure/numbers, selected grade C and absent subclaim score, safety and axes. Distinguish P=.003, the approximately 5% description and missing exact between-group effects/CIs. S01 6-week fitness and S02 9-hour acute metabolism use different protocols, populations, comparators and endpoints. No new effects, CIs, exposure/participant/trial totals, independence certification, grades, exercise instructions, medication changes or treatment guidance are created.", "criterion": "Material for Parent/subclaim original values and verdict history must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.", "basis": "Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.", "condition_origin": "Internally applied conditions preserved for the existing subclaim. They do not establish preregistration, official-tool certification or completed content review.", "proposed_research": "Material needed: Complete preserved originals, historical verdict materials and selected-subclaim/parent boundary checks. This records needed materials; no new research was executed." }, { "item_id": "N26", "question_type": "Evidence condition", "question": "Are bilingual wording, dates and corrections distinguished?", "needed": "Selected/parent bilingual wording, historical date and corrections", "role": "Required", "role_reason": "This condition connects Selected/parent bilingual wording, historical date and corrections with the 6-week fitness question, inactive young adults, stair training versus no training, VO2peak, missing between-group effects/CIs, acute metabolic background, report-specific support and harms.", "application_exception": "Preserve original exposure/numbers, selected grade C and absent subclaim score, safety and axes. Distinguish P=.003, the approximately 5% description and missing exact between-group effects/CIs. S01 6-week fitness and S02 9-hour acute metabolism use different protocols, populations, comparators and endpoints. No new effects, CIs, exposure/participant/trial totals, independence certification, grades, exercise instructions, medication changes or treatment guidance are created.", "criterion": "Material for Selected/parent bilingual wording, historical date and corrections must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.", "basis": "Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.", "condition_origin": "Internally applied conditions preserved for the existing subclaim. They do not establish preregistration, official-tool certification or completed content review.", "proposed_research": "Material needed: Additional original versions, actual corrections, complete pre-change history and translation/editorial review records. This records needed materials; no new research was executed." }, { "item_id": "N27", "question_type": "Evidence condition", "question": "Which materials and links were actually read?", "needed": "Stored-summary reading, external unread materials and needed evidence", "role": "Required", "role_reason": "This condition connects Stored-summary reading, external unread materials and needed evidence with the 6-week fitness question, inactive young adults, stair training versus no training, VO2peak, missing between-group effects/CIs, acute metabolic background, report-specific support and harms.", "application_exception": "Preserve original exposure/numbers, selected grade C and absent subclaim score, safety and axes. Distinguish P=.003, the approximately 5% description and missing exact between-group effects/CIs. S01 6-week fitness and S02 9-hour acute metabolism use different protocols, populations, comparators and endpoints. No new effects, CIs, exposure/participant/trial totals, independence certification, grades, exercise instructions, medication changes or treatment guidance are created.", "criterion": "Material for Stored-summary reading, external unread materials and needed evidence must be linked to the selected subclaim, parent context, same report/trial, outcome units, times, actual comparator and denominators, distinguishing unread external material.", "basis": "Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.", "condition_origin": "Internally applied conditions preserved for the existing subclaim. They do not establish preregistration, official-tool certification or completed content review.", "proposed_research": "Material needed: Report-specific originals, registration, plans, support materials and actual acquisition/reading records. Preserve originals and versions before updating observations. This records needed materials; no new research was executed." } ] }