{
  "schema_version": "chamgap-public-criteria-1.0",
  "title": "Dark chocolate × lasting eyesight and eye health: evidence gaps",
  "language": "en",
  "translation_date": "2026-10-16",
  "criteria_version": "1.0",
  "criteria_date": "2026-10-06",
  "condition_origin": "Chamgap's own application conditions",
  "method_sources": [
    {
      "id": "M03",
      "version": "Cochrane Handbook 6.5 (2024), chapter updated 2023-08",
      "url": "https://www.cochrane.org/authors/handbooks-and-manuals/handbook/current/chapter-03",
      "section": "§3.1, §3.2.1–3.2.3, MECIR C5/C7/C13",
      "official_principle": "Clearly record the question, eligibility conditions and reasons for changes, and distinguish variations in interventions.",
      "review_level": "Link preserved methodological application records; no current clinical-content reassessment or external-link verification was performed."
    },
    {
      "id": "M04",
      "version": "Cochrane Handbook 6.5.1 (2025), chapter updated 2025-03",
      "url": "https://www.cochrane.org/authors/handbooks-and-manuals/handbook/current/chapter-04",
      "section": "§4.5, §4.6.1–4.6.3, MECIR C42",
      "official_principle": "Distinguish studies from reports and link them; do not omit a study solely because results are unreported.",
      "review_level": "Link preserved methodological application records; no current clinical-content reassessment or external-link verification was performed."
    },
    {
      "id": "M08",
      "version": "Cochrane Handbook 6.5 (2024), chapter updated 2019-10",
      "url": "https://www.cochrane.org/authors/handbooks-and-manuals/handbook/current/chapter-08",
      "section": "§8.1–8.2.3, Table 8.2.a",
      "official_principle": "Define the outcome and effect of interest, then examine randomization, deviations, missing data, measurement and selective reporting.",
      "review_level": "Link preserved methodological application records; no current clinical-content reassessment or external-link verification was performed."
    },
    {
      "id": "M15",
      "version": "Cochrane Handbook 6.5 (2024), chapter updated 2023-08",
      "url": "https://www.cochrane.org/authors/handbooks-and-manuals/handbook/current/chapter-15",
      "section": "§15.2.4, §15.3.1–15.3.3",
      "official_principle": "Distinguish effect estimates, intervals, importance and applicability. Sample size alone does not determine precision.",
      "review_level": "Link preserved methodological application records; no current clinical-content reassessment or external-link verification was performed."
    },
    {
      "id": "M19",
      "version": "Cochrane Handbook 6.5 (2024), chapter updated 2019-10",
      "url": "https://www.cochrane.org/authors/handbooks-and-manuals/handbook/current/chapter-19",
      "section": "§19.1.2, §19.2.1–19.2.4",
      "official_principle": "Harm questions may require different designs, populations and follow-up from efficacy questions. Case reports do not establish incidence rates.",
      "review_level": "Link preserved methodological application records; no current clinical-content reassessment or external-link verification was performed."
    }
  ],
  "status_dictionary": {
    "Partly verified": "Some information exists in the preserved review summary; detailed original materials remain unverified. This does not certify a passed review or clinical efficacy.",
    "Unverified": "Detailed materials for the selected condition could not be established within the stored scope; this does not mean zero effect, zero studies or safety",
    "Review incomplete": "Review of existing content incomplete",
    "Met": "Use only within the relevant conditions after existing content review; no automatic designation in this preparation",
    "Not reported": "Distinguish only within materials actually read; do not turn unread external materials into unreported findings",
    "Inaccessible": "Not applied during this preparation because actual access was not tested",
    "Not applicable": "Use with a reason for non-applicability based on an explicit question boundary",
    "Conflicting data": "Judge after actual material comparison; review was not performed during this preparation",
    "Insufficient evidence for the conditions": "Do not use as a clinical grade encompassing currently unread materials"
  },
  "requirements": [
    {
      "item_id": "N01",
      "question_type": "Evidence condition",
      "question": "What are the selected lasting-eyesight/eye-health question and verdict?",
      "needed": "Existing claim of lasting improvement in eyesight or eye health",
      "role": "Required",
      "role_reason": "This condition connects Existing claim of lasting improvement in eyesight or eye health with the selected lasting-eyesight/eye-health question, acute context, tested foods, milk-chocolate control, within-person crossover, people/eyes, conditions, times, denominators, other visual outcomes and harms.",
      "application_exception": "Preserve original numbers while distinguishing tested dark/milk food comparisons from isolated-ingredient effects, small-letter logCS, large-letter logCS and acuity logMAR, the same acute window of about 1.75 hours/about 2 hours/within 2 hours, people/eyes/conditions/repeated tests and long-term clinical efficacy. No new arithmetic, effects, CIs, hypothetical examples, grades, independence certification, amounts, products, eye-health or treatment instructions are created.",
      "criterion": "Material for Existing claim of lasting improvement in eyesight or eye health must be linked to the selected subclaim, parent context, same report/crossover trial, test units, times, comparator and denominators, distinguishing unread external material.",
      "basis": "Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.",
      "condition_origin": "Internally applied conditions preserved for the existing subclaim. They do not establish preregistration, official-tool certification or completed content review.",
      "proposed_research": "Material needed: Direct persistence, everyday clinical-function and eye-health material, and applicability review, remain needed. ? is not converted into effect 0, score 0 or absence of all research. This records needed materials; no new research was executed."
    },
    {
      "item_id": "N02",
      "question_type": "Evidence condition",
      "question": "Was duration of effect directly measured?",
      "needed": "Acute test timing versus persistence follow-up",
      "role": "Required",
      "role_reason": "This condition connects Acute test timing versus persistence follow-up with the selected lasting-eyesight/eye-health question, acute context, tested foods, milk-chocolate control, within-person crossover, people/eyes, conditions, times, denominators, other visual outcomes and harms.",
      "application_exception": "Preserve original numbers while distinguishing tested dark/milk food comparisons from isolated-ingredient effects, small-letter logCS, large-letter logCS and acuity logMAR, the same acute window of about 1.75 hours/about 2 hours/within 2 hours, people/eyes/conditions/repeated tests and long-term clinical efficacy. No new arithmetic, effects, CIs, hypothetical examples, grades, independence certification, amounts, products, eye-health or treatment instructions are created.",
      "criterion": "Material for Acute test timing versus persistence follow-up must be linked to the selected subclaim, parent context, same report/crossover trial, test units, times, comparator and denominators, distinguishing unread external material.",
      "basis": "Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.",
      "condition_origin": "Internally applied conditions preserved for the existing subclaim. They do not establish preregistration, official-tool certification or completed content review.",
      "proposed_research": "Material needed: Later time-specific tests, effects/CIs, exposure, denominators, post-treatment follow-up and duration definitions are needed. No new duration or effect is inferred. This records needed materials; no new research was executed."
    },
    {
      "item_id": "N03",
      "question_type": "Evidence condition",
      "question": "Was everyday clinical function directly tested?",
      "needed": "Laboratory psychophysical tests versus clinical function",
      "role": "Required",
      "role_reason": "This condition connects Laboratory psychophysical tests versus clinical function with the selected lasting-eyesight/eye-health question, acute context, tested foods, milk-chocolate control, within-person crossover, people/eyes, conditions, times, denominators, other visual outcomes and harms.",
      "application_exception": "Preserve original numbers while distinguishing tested dark/milk food comparisons from isolated-ingredient effects, small-letter logCS, large-letter logCS and acuity logMAR, the same acute window of about 1.75 hours/about 2 hours/within 2 hours, people/eyes/conditions/repeated tests and long-term clinical efficacy. No new arithmetic, effects, CIs, hypothetical examples, grades, independence certification, amounts, products, eye-health or treatment instructions are created.",
      "criterion": "Material for Laboratory psychophysical tests versus clinical function must be linked to the selected subclaim, parent context, same report/crossover trial, test units, times, comparator and denominators, distinguishing unread external material.",
      "basis": "Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.",
      "condition_origin": "Internally applied conditions preserved for the existing subclaim. They do not establish preregistration, official-tool certification or completed content review.",
      "proposed_research": "Material needed: Definitions, measurements, denominators, comparators and effects/CIs for patient-important function, everyday activities and long-term eyesight are needed. This records needed materials; no new research was executed."
    },
    {
      "item_id": "N04",
      "question_type": "Evidence condition",
      "question": "What are the original acute small-letter contrast values?",
      "needed": "Original logCS effects/CIs and direct measurement timing",
      "role": "Required",
      "role_reason": "This condition connects Original logCS effects/CIs and direct measurement timing with the selected lasting-eyesight/eye-health question, acute context, tested foods, milk-chocolate control, within-person crossover, people/eyes, conditions, times, denominators, other visual outcomes and harms.",
      "application_exception": "Preserve original numbers while distinguishing tested dark/milk food comparisons from isolated-ingredient effects, small-letter logCS, large-letter logCS and acuity logMAR, the same acute window of about 1.75 hours/about 2 hours/within 2 hours, people/eyes/conditions/repeated tests and long-term clinical efficacy. No new arithmetic, effects, CIs, hypothetical examples, grades, independence certification, amounts, products, eye-health or treatment instructions are created.",
      "criterion": "Material for Original logCS effects/CIs and direct measurement timing must be linked to the selected subclaim, parent context, same report/crossover trial, test units, times, comparator and denominators, distinguishing unread external material.",
      "basis": "Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.",
      "condition_origin": "Internally applied conditions preserved for the existing subclaim. They do not establish preregistration, official-tool certification or completed content review.",
      "proposed_research": "Material needed: Separate originals for persistence/clinical questions and acute tables, definitions, models and condition-specific denominators are needed. No new effects, CIs or relative changes are calculated. This records needed materials; no new research was executed."
    },
    {
      "item_id": "N05",
      "question_type": "Evidence condition",
      "question": "Does large-letter contrast show the same result?",
      "needed": "Distinguishing small- and large-letter logCS",
      "role": "Required",
      "role_reason": "This condition connects Distinguishing small- and large-letter logCS with the selected lasting-eyesight/eye-health question, acute context, tested foods, milk-chocolate control, within-person crossover, people/eyes, conditions, times, denominators, other visual outcomes and harms.",
      "application_exception": "Preserve original numbers while distinguishing tested dark/milk food comparisons from isolated-ingredient effects, small-letter logCS, large-letter logCS and acuity logMAR, the same acute window of about 1.75 hours/about 2 hours/within 2 hours, people/eyes/conditions/repeated tests and long-term clinical efficacy. No new arithmetic, effects, CIs, hypothetical examples, grades, independence certification, amounts, products, eye-health or treatment instructions are created.",
      "criterion": "Material for Distinguishing small- and large-letter logCS must be linked to the selected subclaim, parent context, same report/crossover trial, test units, times, comparator and denominators, distinguishing unread external material.",
      "basis": "Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.",
      "condition_origin": "Internally applied conditions preserved for the existing subclaim. They do not establish preregistration, official-tool certification or completed content review.",
      "proposed_research": "Material needed: Large-letter tests, denominators, effects/CIs, prior hierarchy, multiplicity and direct persistence material are needed. P=.07 does not certify effect 0 or equivalence. This records needed materials; no new research was executed."
    },
    {
      "item_id": "N06",
      "question_type": "Evidence condition",
      "question": "Are visual acuity in logMAR and contrast in logCS the same?",
      "needed": "Distinguishing acuity/contrast measures and units",
      "role": "Required",
      "role_reason": "This condition connects Distinguishing acuity/contrast measures and units with the selected lasting-eyesight/eye-health question, acute context, tested foods, milk-chocolate control, within-person crossover, people/eyes, conditions, times, denominators, other visual outcomes and harms.",
      "application_exception": "Preserve original numbers while distinguishing tested dark/milk food comparisons from isolated-ingredient effects, small-letter logCS, large-letter logCS and acuity logMAR, the same acute window of about 1.75 hours/about 2 hours/within 2 hours, people/eyes/conditions/repeated tests and long-term clinical efficacy. No new arithmetic, effects, CIs, hypothetical examples, grades, independence certification, amounts, products, eye-health or treatment instructions are created.",
      "criterion": "Material for Distinguishing acuity/contrast measures and units must be linked to the selected subclaim, parent context, same report/crossover trial, test units, times, comparator and denominators, distinguishing unread external material.",
      "basis": "Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.",
      "condition_origin": "Internally applied conditions preserved for the existing subclaim. They do not establish preregistration, official-tool certification or completed content review.",
      "proposed_research": "Material needed: Original acuity tables, condition-specific denominators, comparative CIs, exact times, prior hierarchy, importance and persistence material are needed. This records needed materials; no new research was executed."
    },
    {
      "item_id": "N07",
      "question_type": "Evidence condition",
      "question": "Are clinical eye-health or eye-disease event data available?",
      "needed": "Specific eye-health endpoints and clinical-event gaps",
      "role": "Required",
      "role_reason": "This condition connects Specific eye-health endpoints and clinical-event gaps with the selected lasting-eyesight/eye-health question, acute context, tested foods, milk-chocolate control, within-person crossover, people/eyes, conditions, times, denominators, other visual outcomes and harms.",
      "application_exception": "Preserve original numbers while distinguishing tested dark/milk food comparisons from isolated-ingredient effects, small-letter logCS, large-letter logCS and acuity logMAR, the same acute window of about 1.75 hours/about 2 hours/within 2 hours, people/eyes/conditions/repeated tests and long-term clinical efficacy. No new arithmetic, effects, CIs, hypothetical examples, grades, independence certification, amounts, products, eye-health or treatment instructions are created.",
      "criterion": "Material for Specific eye-health endpoints and clinical-event gaps must be linked to the selected subclaim, parent context, same report/crossover trial, test units, times, comparator and denominators, distinguishing unread external material.",
      "basis": "Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.",
      "condition_origin": "Internally applied conditions preserved for the existing subclaim. They do not establish preregistration, official-tool certification or completed content review.",
      "proposed_research": "Material needed: Disease/event definitions, clinical adjudication, group-specific events/denominators, follow-up and original CIs are needed. Unverified data are not converted into event 0 or preventive effect 0. This records needed materials; no new research was executed."
    },
    {
      "item_id": "N08",
      "question_type": "Evidence condition",
      "question": "Are healthy young adults the same as eye-disease patients?",
      "needed": "30 people without eye disease, eligibility and generalization",
      "role": "Required",
      "role_reason": "This condition connects 30 people without eye disease, eligibility and generalization with the selected lasting-eyesight/eye-health question, acute context, tested foods, milk-chocolate control, within-person crossover, people/eyes, conditions, times, denominators, other visual outcomes and harms.",
      "application_exception": "Preserve original numbers while distinguishing tested dark/milk food comparisons from isolated-ingredient effects, small-letter logCS, large-letter logCS and acuity logMAR, the same acute window of about 1.75 hours/about 2 hours/within 2 hours, people/eyes/conditions/repeated tests and long-term clinical efficacy. No new arithmetic, effects, CIs, hypothetical examples, grades, independence certification, amounts, products, eye-health or treatment instructions are created.",
      "criterion": "Material for 30 people without eye disease, eligibility and generalization must be linked to the selected subclaim, parent context, same report/crossover trial, test units, times, comparator and denominators, distinguishing unread external material.",
      "basis": "Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.",
      "condition_origin": "Internally applied conditions preserved for the existing subclaim. They do not establish preregistration, official-tool certification or completed content review.",
      "proposed_research": "Material needed: Eligibility, exclusions, age, baseline vision, eye disease, medicines and original denominators for direct long-term populations are needed. This records needed materials; no new research was executed."
    },
    {
      "item_id": "N09",
      "question_type": "Evidence condition",
      "question": "Is the actual comparison dark versus milk chocolate?",
      "needed": "Two tested foods and an active control",
      "role": "Required",
      "role_reason": "This condition connects Two tested foods and an active control with the selected lasting-eyesight/eye-health question, acute context, tested foods, milk-chocolate control, within-person crossover, people/eyes, conditions, times, denominators, other visual outcomes and harms.",
      "application_exception": "Preserve original numbers while distinguishing tested dark/milk food comparisons from isolated-ingredient effects, small-letter logCS, large-letter logCS and acuity logMAR, the same acute window of about 1.75 hours/about 2 hours/within 2 hours, people/eyes/conditions/repeated tests and long-term clinical efficacy. No new arithmetic, effects, CIs, hypothetical examples, grades, independence certification, amounts, products, eye-health or treatment instructions are created.",
      "criterion": "Material for Two tested foods and an active control must be linked to the selected subclaim, parent context, same report/crossover trial, test units, times, comparator and denominators, distinguishing unread external material.",
      "basis": "Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.",
      "condition_origin": "Internally applied conditions preserved for the existing subclaim. They do not establish preregistration, official-tool certification or completed content review.",
      "proposed_research": "Material needed: Product composition, actual exposure, flavanols, cacao, sugar, calories, control matching and masking material are needed. No amounts or product recommendations are created. This records needed materials; no new research was executed."
    },
    {
      "item_id": "N10",
      "question_type": "Evidence condition",
      "question": "Does cacao percentage alone ensure the same flavanol exposure?",
      "needed": "Tested versus general products and unrecorded amounts",
      "role": "Required",
      "role_reason": "This condition connects Tested versus general products and unrecorded amounts with the selected lasting-eyesight/eye-health question, acute context, tested foods, milk-chocolate control, within-person crossover, people/eyes, conditions, times, denominators, other visual outcomes and harms.",
      "application_exception": "Preserve original numbers while distinguishing tested dark/milk food comparisons from isolated-ingredient effects, small-letter logCS, large-letter logCS and acuity logMAR, the same acute window of about 1.75 hours/about 2 hours/within 2 hours, people/eyes/conditions/repeated tests and long-term clinical efficacy. No new arithmetic, effects, CIs, hypothetical examples, grades, independence certification, amounts, products, eye-health or treatment instructions are created.",
      "criterion": "Material for Tested versus general products and unrecorded amounts must be linked to the selected subclaim, parent context, same report/crossover trial, test units, times, comparator and denominators, distinguishing unread external material.",
      "basis": "Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.",
      "condition_origin": "Internally applied conditions preserved for the existing subclaim. They do not establish preregistration, official-tool certification or completed content review.",
      "proposed_research": "Material needed: Tested-product quantities, ingredients, batch, manufacturing, actual exposure and control composition are needed. No new ingestion doses or long-term exposure examples are created. This records needed materials; no new research was executed."
    },
    {
      "item_id": "N11",
      "question_type": "Evidence condition",
      "question": "Are the 30 crossover participants new people in each condition?",
      "needed": "Within-person single-exposure conditions, denominators and repeats",
      "role": "Required",
      "role_reason": "This condition connects Within-person single-exposure conditions, denominators and repeats with the selected lasting-eyesight/eye-health question, acute context, tested foods, milk-chocolate control, within-person crossover, people/eyes, conditions, times, denominators, other visual outcomes and harms.",
      "application_exception": "Preserve original numbers while distinguishing tested dark/milk food comparisons from isolated-ingredient effects, small-letter logCS, large-letter logCS and acuity logMAR, the same acute window of about 1.75 hours/about 2 hours/within 2 hours, people/eyes/conditions/repeated tests and long-term clinical efficacy. No new arithmetic, effects, CIs, hypothetical examples, grades, independence certification, amounts, products, eye-health or treatment instructions are created.",
      "criterion": "Material for Within-person single-exposure conditions, denominators and repeats must be linked to the selected subclaim, parent context, same report/crossover trial, test units, times, comparator and denominators, distinguishing unread external material.",
      "basis": "Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.",
      "condition_origin": "Internally applied conditions preserved for the existing subclaim. They do not establish preregistration, official-tool certification or completed content review.",
      "proposed_research": "Material needed: Allocation order, periods, washout, carryover, condition/outcome denominators, missingness and within-person models are needed. No new total observations or participant counts are calculated. This records needed materials; no new research was executed."
    },
    {
      "item_id": "N12",
      "question_type": "Evidence condition",
      "question": "Are single masking and possible chocolate recognition distinguished?",
      "needed": "Measurement/participant masking and bias",
      "role": "Required",
      "role_reason": "This condition connects Measurement/participant masking and bias with the selected lasting-eyesight/eye-health question, acute context, tested foods, milk-chocolate control, within-person crossover, people/eyes, conditions, times, denominators, other visual outcomes and harms.",
      "application_exception": "Preserve original numbers while distinguishing tested dark/milk food comparisons from isolated-ingredient effects, small-letter logCS, large-letter logCS and acuity logMAR, the same acute window of about 1.75 hours/about 2 hours/within 2 hours, people/eyes/conditions/repeated tests and long-term clinical efficacy. No new arithmetic, effects, CIs, hypothetical examples, grades, independence certification, amounts, products, eye-health or treatment instructions are created.",
      "criterion": "Material for Measurement/participant masking and bias must be linked to the selected subclaim, parent context, same report/crossover trial, test units, times, comparator and denominators, distinguishing unread external material.",
      "basis": "Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.",
      "condition_origin": "Internally applied conditions preserved for the existing subclaim. They do not establish preregistration, official-tool certification or completed content review.",
      "proposed_research": "Material needed: Who was masked, concealment, recognition assessment, assessors, test learning, order and missing-data originals are needed. Possibility is not regraded as a confirmed violation or null effect. This records needed materials; no new research was executed."
    },
    {
      "item_id": "N13",
      "question_type": "Evidence condition",
      "question": "Did registration and prior outcomes include the lasting-effect question?",
      "needed": "NCT03326934 and acute/long-term hierarchy",
      "role": "Required",
      "role_reason": "This condition connects NCT03326934 and acute/long-term hierarchy with the selected lasting-eyesight/eye-health question, acute context, tested foods, milk-chocolate control, within-person crossover, people/eyes, conditions, times, denominators, other visual outcomes and harms.",
      "application_exception": "Preserve original numbers while distinguishing tested dark/milk food comparisons from isolated-ingredient effects, small-letter logCS, large-letter logCS and acuity logMAR, the same acute window of about 1.75 hours/about 2 hours/within 2 hours, people/eyes/conditions/repeated tests and long-term clinical efficacy. No new arithmetic, effects, CIs, hypothetical examples, grades, independence certification, amounts, products, eye-health or treatment instructions are created.",
      "criterion": "Material for NCT03326934 and acute/long-term hierarchy must be linked to the selected subclaim, parent context, same report/crossover trial, test units, times, comparator and denominators, distinguishing unread external material.",
      "basis": "Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.",
      "condition_origin": "Internally applied conditions preserved for the existing subclaim. They do not establish preregistration, official-tool certification or completed content review.",
      "proposed_research": "Material needed: Initial registration, change history, protocols, SAPs, outcomes/times, multiplicity and analysis populations are needed. Identifiers are distinguished from actual content verification. This records needed materials; no new research was executed."
    },
    {
      "item_id": "N14",
      "question_type": "Evidence condition",
      "question": "Does the acute CI establish precision of lasting effects?",
      "needed": "Acute CI versus precision of persistence/clinical effects",
      "role": "Required",
      "role_reason": "This condition connects Acute CI versus precision of persistence/clinical effects with the selected lasting-eyesight/eye-health question, acute context, tested foods, milk-chocolate control, within-person crossover, people/eyes, conditions, times, denominators, other visual outcomes and harms.",
      "application_exception": "Preserve original numbers while distinguishing tested dark/milk food comparisons from isolated-ingredient effects, small-letter logCS, large-letter logCS and acuity logMAR, the same acute window of about 1.75 hours/about 2 hours/within 2 hours, people/eyes/conditions/repeated tests and long-term clinical efficacy. No new arithmetic, effects, CIs, hypothetical examples, grades, independence certification, amounts, products, eye-health or treatment instructions are created.",
      "criterion": "Material for Acute CI versus precision of persistence/clinical effects must be linked to the selected subclaim, parent context, same report/crossover trial, test units, times, comparator and denominators, distinguishing unread external material.",
      "basis": "Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.",
      "condition_origin": "Internally applied conditions preserved for the existing subclaim. They do not establish preregistration, official-tool certification or completed content review.",
      "proposed_research": "Material needed: Direct long-term effects/CIs, patient importance, denominators and follow-up are needed. Parent C0/effect-size interpretation is not transferred to long-term subclaim values. This records needed materials; no new research was executed."
    },
    {
      "item_id": "N15",
      "question_type": "Evidence condition",
      "question": "Are data available on repeated ingestion and post-treatment persistence?",
      "needed": "Repeated exposure and direct long-term function/events",
      "role": "Required",
      "role_reason": "This condition connects Repeated exposure and direct long-term function/events with the selected lasting-eyesight/eye-health question, acute context, tested foods, milk-chocolate control, within-person crossover, people/eyes, conditions, times, denominators, other visual outcomes and harms.",
      "application_exception": "Preserve original numbers while distinguishing tested dark/milk food comparisons from isolated-ingredient effects, small-letter logCS, large-letter logCS and acuity logMAR, the same acute window of about 1.75 hours/about 2 hours/within 2 hours, people/eyes/conditions/repeated tests and long-term clinical efficacy. No new arithmetic, effects, CIs, hypothetical examples, grades, independence certification, amounts, products, eye-health or treatment instructions are created.",
      "criterion": "Material for Repeated exposure and direct long-term function/events must be linked to the selected subclaim, parent context, same report/crossover trial, test units, times, comparator and denominators, distinguishing unread external material.",
      "basis": "Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.",
      "condition_origin": "Internally applied conditions preserved for the existing subclaim. They do not establish preregistration, official-tool certification or completed content review.",
      "proposed_research": "Material needed: Repeated/later function, disease endpoints, denominators, CIs, actual exposure and harms with the same product/control are needed. Only research needs are recorded; no ingestion, product or treatment instructions are created. This records needed materials; no new research was executed."
    },
    {
      "item_id": "N16",
      "question_type": "Evidence condition",
      "question": "Are the same trial, eyes and conditions counted as new independent material?",
      "needed": "Shared bibliography/participants across parent and two subclaims",
      "role": "Required",
      "role_reason": "This condition connects Shared bibliography/participants across parent and two subclaims with the selected lasting-eyesight/eye-health question, acute context, tested foods, milk-chocolate control, within-person crossover, people/eyes, conditions, times, denominators, other visual outcomes and harms.",
      "application_exception": "Preserve original numbers while distinguishing tested dark/milk food comparisons from isolated-ingredient effects, small-letter logCS, large-letter logCS and acuity logMAR, the same acute window of about 1.75 hours/about 2 hours/within 2 hours, people/eyes/conditions/repeated tests and long-term clinical efficacy. No new arithmetic, effects, CIs, hypothetical examples, grades, independence certification, amounts, products, eye-health or treatment instructions are created.",
      "criterion": "Material for Shared bibliography/participants across parent and two subclaims must be linked to the selected subclaim, parent context, same report/crossover trial, test units, times, comparator and denominators, distinguishing unread external material.",
      "basis": "Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.",
      "condition_origin": "Internally applied conditions preserved for the existing subclaim. They do not establish preregistration, official-tool certification or completed content review.",
      "proposed_research": "Material needed: Links among reports, populations, people, eyes, times, conditions and analysis populations are needed. Material slots are not quality scores or unique-trial counts. This records needed materials; no new research was executed."
    },
    {
      "item_id": "N17",
      "question_type": "Evidence condition",
      "question": "What material was actually read?",
      "needed": "Complete parent stored summary versus external reading",
      "role": "Required",
      "role_reason": "This condition connects Complete parent stored summary versus external reading with the selected lasting-eyesight/eye-health question, acute context, tested foods, milk-chocolate control, within-person crossover, people/eyes, conditions, times, denominators, other visual outcomes and harms.",
      "application_exception": "Preserve original numbers while distinguishing tested dark/milk food comparisons from isolated-ingredient effects, small-letter logCS, large-letter logCS and acuity logMAR, the same acute window of about 1.75 hours/about 2 hours/within 2 hours, people/eyes/conditions/repeated tests and long-term clinical efficacy. No new arithmetic, effects, CIs, hypothetical examples, grades, independence certification, amounts, products, eye-health or treatment instructions are created.",
      "criterion": "Material for Complete parent stored summary versus external reading must be linked to the selected subclaim, parent context, same report/crossover trial, test units, times, comparator and denominators, distinguishing unread external material.",
      "basis": "Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.",
      "condition_origin": "Internally applied conditions preserved for the existing subclaim. They do not establish preregistration, official-tool certification or completed content review.",
      "proposed_research": "Material needed: Actual original papers, appendices, registration, plans and reading records are needed. External-source content verification and link testing were not performed this time. This records needed materials; no new research was executed."
    },
    {
      "item_id": "N18",
      "question_type": "Evidence condition",
      "question": "What are the bibliographic and registration identifiers?",
      "needed": "PMID, PMCID, DOI and registration identification/content",
      "role": "Required",
      "role_reason": "This condition connects PMID, PMCID, DOI and registration identification/content with the selected lasting-eyesight/eye-health question, acute context, tested foods, milk-chocolate control, within-person crossover, people/eyes, conditions, times, denominators, other visual outcomes and harms.",
      "application_exception": "Preserve original numbers while distinguishing tested dark/milk food comparisons from isolated-ingredient effects, small-letter logCS, large-letter logCS and acuity logMAR, the same acute window of about 1.75 hours/about 2 hours/within 2 hours, people/eyes/conditions/repeated tests and long-term clinical efficacy. No new arithmetic, effects, CIs, hypothetical examples, grades, independence certification, amounts, products, eye-health or treatment instructions are created.",
      "criterion": "Material for PMID, PMCID, DOI and registration identification/content must be linked to the selected subclaim, parent context, same report/crossover trial, test units, times, comparator and denominators, distinguishing unread external material.",
      "basis": "Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.",
      "condition_origin": "Internally applied conditions preserved for the existing subclaim. They do not establish preregistration, official-tool certification or completed content review.",
      "proposed_research": "Material needed: Accurate paper/full-text/registration links, contents and dates are needed. New full-text/registration URLs are not inferred from identifiers. This records needed materials; no new research was executed."
    },
    {
      "item_id": "N19",
      "question_type": "Evidence condition",
      "question": "Are original bilingual text and historical checks distinguished from current review?",
      "needed": "Original Korean/English text, subclaim wording and historical scope",
      "role": "Required",
      "role_reason": "This condition connects Original Korean/English text, subclaim wording and historical scope with the selected lasting-eyesight/eye-health question, acute context, tested foods, milk-chocolate control, within-person crossover, people/eyes, conditions, times, denominators, other visual outcomes and harms.",
      "application_exception": "Preserve original numbers while distinguishing tested dark/milk food comparisons from isolated-ingredient effects, small-letter logCS, large-letter logCS and acuity logMAR, the same acute window of about 1.75 hours/about 2 hours/within 2 hours, people/eyes/conditions/repeated tests and long-term clinical efficacy. No new arithmetic, effects, CIs, hypothetical examples, grades, independence certification, amounts, products, eye-health or treatment instructions are created.",
      "criterion": "Material for Original Korean/English text, subclaim wording and historical scope must be linked to the selected subclaim, parent context, same report/crossover trial, test units, times, comparator and denominators, distinguishing unread external material.",
      "basis": "Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.",
      "condition_origin": "Internally applied conditions preserved for the existing subclaim. They do not establish preregistration, official-tool certification or completed content review.",
      "proposed_research": "Material needed: Content review of originals, detailed translation, corrections and question boundaries remains incomplete. Historical checks are not labeled independent clinical verification now. This records needed materials; no new research was executed."
    },
    {
      "item_id": "N20",
      "question_type": "Evidence condition",
      "question": "Are subclaim values distinguished from parent C54, axes and safety?",
      "needed": "Subclaim grade/note and absent score/status/axes",
      "role": "Required",
      "role_reason": "This condition connects Subclaim grade/note and absent score/status/axes with the selected lasting-eyesight/eye-health question, acute context, tested foods, milk-chocolate control, within-person crossover, people/eyes, conditions, times, denominators, other visual outcomes and harms.",
      "application_exception": "Preserve original numbers while distinguishing tested dark/milk food comparisons from isolated-ingredient effects, small-letter logCS, large-letter logCS and acuity logMAR, the same acute window of about 1.75 hours/about 2 hours/within 2 hours, people/eyes/conditions/repeated tests and long-term clinical efficacy. No new arithmetic, effects, CIs, hypothetical examples, grades, independence certification, amounts, products, eye-health or treatment instructions are created.",
      "criterion": "Material for Subclaim grade/note and absent score/status/axes must be linked to the selected subclaim, parent context, same report/crossover trial, test units, times, comparator and denominators, distinguishing unread external material.",
      "basis": "Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.",
      "condition_origin": "Internally applied conditions preserved for the existing subclaim. They do not establish preregistration, official-tool certification or completed content review.",
      "proposed_research": "Material needed: Content review of selected/parent original values remains incomplete. No new efficacy grades, scores, axes or regrading are created. This records needed materials; no new research was executed."
    },
    {
      "item_id": "N21",
      "question_type": "Evidence condition",
      "question": "Are the evidence date and corrections distinguished from production dates?",
      "needed": "Original evidence date and empty correction/deliberation records",
      "role": "Required",
      "role_reason": "This condition connects Original evidence date and empty correction/deliberation records with the selected lasting-eyesight/eye-health question, acute context, tested foods, milk-chocolate control, within-person crossover, people/eyes, conditions, times, denominators, other visual outcomes and harms.",
      "application_exception": "Preserve original numbers while distinguishing tested dark/milk food comparisons from isolated-ingredient effects, small-letter logCS, large-letter logCS and acuity logMAR, the same acute window of about 1.75 hours/about 2 hours/within 2 hours, people/eyes/conditions/repeated tests and long-term clinical efficacy. No new arithmetic, effects, CIs, hypothetical examples, grades, independence certification, amounts, products, eye-health or treatment instructions are created.",
      "criterion": "Material for Original evidence date and empty correction/deliberation records must be linked to the selected subclaim, parent context, same report/crossover trial, test units, times, comparator and denominators, distinguishing unread external material.",
      "basis": "Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.",
      "condition_origin": "Internally applied conditions preserved for the existing subclaim. They do not establish preregistration, official-tool certification or completed content review.",
      "proposed_research": "Material needed: Later/correction originals, complete before-change text and event history are needed. Absent dates/correction values are not arbitrarily filled. This records needed materials; no new research was executed."
    },
    {
      "item_id": "N22",
      "question_type": "Evidence condition",
      "question": "Are funding, product support, employee authors and analysis roles distinguished?",
      "needed": "Four company-related dimensions and original independence statements",
      "role": "Required",
      "role_reason": "This condition connects Four company-related dimensions and original independence statements with the selected lasting-eyesight/eye-health question, acute context, tested foods, milk-chocolate control, within-person crossover, people/eyes, conditions, times, denominators, other visual outcomes and harms.",
      "application_exception": "Preserve original numbers while distinguishing tested dark/milk food comparisons from isolated-ingredient effects, small-letter logCS, large-letter logCS and acuity logMAR, the same acute window of about 1.75 hours/about 2 hours/within 2 hours, people/eyes/conditions/repeated tests and long-term clinical efficacy. No new arithmetic, effects, CIs, hypothetical examples, grades, independence certification, amounts, products, eye-health or treatment instructions are created.",
      "criterion": "Material for Four company-related dimensions and original independence statements must be linked to the selected subclaim, parent context, same report/crossover trial, test units, times, comparator and denominators, distinguishing unread external material.",
      "basis": "Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.",
      "condition_origin": "Internally applied conditions preserved for the existing subclaim. They do not establish preregistration, official-tool certification or completed content review.",
      "proposed_research": "Material needed: Original funding/competing interests, product support, author affiliations and analysis/publication roles are needed. Parent I2 is not promoted to new independence certification. This records needed materials; no new research was executed."
    },
    {
      "item_id": "N23",
      "question_type": "Evidence condition",
      "question": "Are allocation, measurement, missingness and selective-reporting details available?",
      "needed": "Original design, hierarchy and denominators",
      "role": "Required",
      "role_reason": "This condition connects Original design, hierarchy and denominators with the selected lasting-eyesight/eye-health question, acute context, tested foods, milk-chocolate control, within-person crossover, people/eyes, conditions, times, denominators, other visual outcomes and harms.",
      "application_exception": "Preserve original numbers while distinguishing tested dark/milk food comparisons from isolated-ingredient effects, small-letter logCS, large-letter logCS and acuity logMAR, the same acute window of about 1.75 hours/about 2 hours/within 2 hours, people/eyes/conditions/repeated tests and long-term clinical efficacy. No new arithmetic, effects, CIs, hypothetical examples, grades, independence certification, amounts, products, eye-health or treatment instructions are created.",
      "criterion": "Material for Original design, hierarchy and denominators must be linked to the selected subclaim, parent context, same report/crossover trial, test units, times, comparator and denominators, distinguishing unread external material.",
      "basis": "Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.",
      "condition_origin": "Internally applied conditions preserved for the existing subclaim. They do not establish preregistration, official-tool certification or completed content review.",
      "proposed_research": "Material needed: Methods, protocols, SAPs, registry changes, original tables, effects of interest and denominators are needed. Design labels alone do not certify official RoB/GRADE or passed content review. This records needed materials; no new research was executed."
    },
    {
      "item_id": "N24",
      "question_type": "Evidence condition",
      "question": "Have actual exposure, concurrent care and repetition been verified?",
      "needed": "Original intervention identity, adherence and co-interventions",
      "role": "Required",
      "role_reason": "This condition connects Original intervention identity, adherence and co-interventions with the selected lasting-eyesight/eye-health question, acute context, tested foods, milk-chocolate control, within-person crossover, people/eyes, conditions, times, denominators, other visual outcomes and harms.",
      "application_exception": "Preserve original numbers while distinguishing tested dark/milk food comparisons from isolated-ingredient effects, small-letter logCS, large-letter logCS and acuity logMAR, the same acute window of about 1.75 hours/about 2 hours/within 2 hours, people/eyes/conditions/repeated tests and long-term clinical efficacy. No new arithmetic, effects, CIs, hypothetical examples, grades, independence certification, amounts, products, eye-health or treatment instructions are created.",
      "criterion": "Material for Original intervention identity, adherence and co-interventions must be linked to the selected subclaim, parent context, same report/crossover trial, test units, times, comparator and denominators, distinguishing unread external material.",
      "basis": "Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.",
      "condition_origin": "Internally applied conditions preserved for the existing subclaim. They do not establish preregistration, official-tool certification or completed content review.",
      "proposed_research": "Material needed: Product/formulation quantities, actual exposure, concurrent care, intervention deviations and denominators are needed. No total amounts or ingestion/product/eye-health instructions are created. This records needed materials; no new research was executed."
    },
    {
      "item_id": "N25",
      "question_type": "Evidence condition",
      "question": "Are harm-reporting scope and actual denominators distinguished?",
      "needed": "Original safety statements, collection and exposure denominators",
      "role": "Supplementary",
      "role_reason": "This condition connects Original safety statements, collection and exposure denominators with the selected lasting-eyesight/eye-health question, acute context, tested foods, milk-chocolate control, within-person crossover, people/eyes, conditions, times, denominators, other visual outcomes and harms.",
      "application_exception": "Preserve original numbers while distinguishing tested dark/milk food comparisons from isolated-ingredient effects, small-letter logCS, large-letter logCS and acuity logMAR, the same acute window of about 1.75 hours/about 2 hours/within 2 hours, people/eyes/conditions/repeated tests and long-term clinical efficacy. No new arithmetic, effects, CIs, hypothetical examples, grades, independence certification, amounts, products, eye-health or treatment instructions are created.",
      "criterion": "Material for Original safety statements, collection and exposure denominators must be linked to the selected subclaim, parent context, same report/crossover trial, test units, times, comparator and denominators, distinguishing unread external material.",
      "basis": "Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.",
      "condition_origin": "Internally applied conditions preserved for the existing subclaim. They do not establish preregistration, official-tool certification or completed content review.",
      "proposed_research": "Material needed: Harm definitions, collection, actual exposure/denominators, discontinuation, dropout, severity and control originals are needed. Original Good safety is not transferred to safety in all populations/durations. This records needed materials; no new research was executed."
    },
    {
      "item_id": "N26",
      "question_type": "Evidence condition",
      "question": "What are the boundaries for long-term/rare harms and other populations?",
      "needed": "Original duration, illnesses, medicines and long-term boundaries",
      "role": "Supplementary",
      "role_reason": "This condition connects Original duration, illnesses, medicines and long-term boundaries with the selected lasting-eyesight/eye-health question, acute context, tested foods, milk-chocolate control, within-person crossover, people/eyes, conditions, times, denominators, other visual outcomes and harms.",
      "application_exception": "Preserve original numbers while distinguishing tested dark/milk food comparisons from isolated-ingredient effects, small-letter logCS, large-letter logCS and acuity logMAR, the same acute window of about 1.75 hours/about 2 hours/within 2 hours, people/eyes/conditions/repeated tests and long-term clinical efficacy. No new arithmetic, effects, CIs, hypothetical examples, grades, independence certification, amounts, products, eye-health or treatment instructions are created.",
      "criterion": "Material for Original duration, illnesses, medicines and long-term boundaries must be linked to the selected subclaim, parent context, same report/crossover trial, test units, times, comparator and denominators, distinguishing unread external material.",
      "basis": "Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.",
      "condition_origin": "Internally applied conditions preserved for the existing subclaim. They do not establish preregistration, official-tool certification or completed content review.",
      "proposed_research": "Material needed: Long-term exposure/follow-up, harm surveillance, risk groups, medicines, denominators, CIs and event data are needed. No new treatment, ingestion or care instructions are provided. This records needed materials; no new research was executed."
    },
    {
      "item_id": "N27",
      "question_type": "Evidence condition",
      "question": "What material would trigger a sheet update?",
      "needed": "Conditions, observations, original material and verdict-change events",
      "role": "Required",
      "role_reason": "This condition connects Conditions, observations, original material and verdict-change events with the selected lasting-eyesight/eye-health question, acute context, tested foods, milk-chocolate control, within-person crossover, people/eyes, conditions, times, denominators, other visual outcomes and harms.",
      "application_exception": "Preserve original numbers while distinguishing tested dark/milk food comparisons from isolated-ingredient effects, small-letter logCS, large-letter logCS and acuity logMAR, the same acute window of about 1.75 hours/about 2 hours/within 2 hours, people/eyes/conditions/repeated tests and long-term clinical efficacy. No new arithmetic, effects, CIs, hypothetical examples, grades, independence certification, amounts, products, eye-health or treatment instructions are created.",
      "criterion": "Material for Conditions, observations, original material and verdict-change events must be linked to the selected subclaim, parent context, same report/crossover trial, test units, times, comparator and denominators, distinguishing unread external material.",
      "basis": "Preserved C/E/H application conditions concerning questions, populations, interventions, comparators, reports versus studies, endpoints, denominators and harms were referenced.",
      "condition_origin": "Internally applied conditions preserved for the existing subclaim. They do not establish preregistration, official-tool certification or completed content review.",
      "proposed_research": "Material needed: Complete before-change copies, original material, condition versions, separate application and content-review records are needed. Material additions, condition revisions and verdict changes are distinguished. This records needed materials; no new research was executed."
    }
  ]
}