{
  "schema_version": "chamgap-public-criteria-1.0",
  "title": "Green Mediterranean diet × Liver-fat reduction from Mankai or green tea alone",
  "language": "en",
  "translation_date": "2026-10-15",
  "criteria_version": "1.0",
  "criteria_date": "2026-10-06",
  "condition_origin": "Chamgap's own application conditions",
  "method_sources": [
    {
      "id": "M03",
      "version": "Cochrane Handbook 6.5 (2024), chapter updated 2023-08",
      "url": "https://www.cochrane.org/authors/handbooks-and-manuals/handbook/current/chapter-03",
      "section": "§3.1, §3.2.1–3.2.3, MECIR C5/C7/C13",
      "official_principle": "Clearly record the question, eligibility conditions and reasons for changes, and distinguish variations in interventions.",
      "review_level": "Preserved method HTML copies; no current method-content re-review or official tool execution"
    },
    {
      "id": "M04",
      "version": "Cochrane Handbook 6.5.1 (2025), chapter updated 2025-03",
      "url": "https://www.cochrane.org/authors/handbooks-and-manuals/handbook/current/chapter-04",
      "section": "§4.5, §4.6.1–4.6.3, MECIR C42",
      "official_principle": "Distinguish studies from reports and link them; do not omit a study solely because results are unreported.",
      "review_level": "Preserved method HTML copies; no current method-content re-review or official tool execution"
    },
    {
      "id": "M08",
      "version": "Cochrane Handbook 6.5 (2024), chapter updated 2019-10",
      "url": "https://www.cochrane.org/authors/handbooks-and-manuals/handbook/current/chapter-08",
      "section": "§8.1–8.2.3, Table 8.2.a",
      "official_principle": "Define the outcome and effect of interest, then examine randomization, deviations, missing data, measurement and selective reporting.",
      "review_level": "Preserved method HTML copies; no current method-content re-review or official tool execution"
    },
    {
      "id": "M15",
      "version": "Cochrane Handbook 6.5 (2024), chapter updated 2023-08",
      "url": "https://www.cochrane.org/authors/handbooks-and-manuals/handbook/current/chapter-15",
      "section": "§15.2.4, §15.3.1–15.3.3",
      "official_principle": "Distinguish effect estimates, intervals, importance and applicability. Sample size alone does not determine precision.",
      "review_level": "Preserved method HTML copies; no current method-content re-review or official tool execution"
    },
    {
      "id": "M19",
      "version": "Cochrane Handbook 6.5 (2024), chapter updated 2019-10",
      "url": "https://www.cochrane.org/authors/handbooks-and-manuals/handbook/current/chapter-19",
      "section": "§19.1.2, §19.2.1–19.2.4",
      "official_principle": "Harm questions may require different designs, populations and follow-up from efficacy questions. Case reports do not establish incidence rates.",
      "review_level": "Preserved method HTML copies; no current method-content re-review or official tool execution"
    }
  ],
  "status_dictionary": {
    "Met": "Status for necessary evidence confirmed after existing content review. No completion is declared in the current presentation.",
    "Partly verified": "Some information in the stored summary is linked into the table. External comparison/content review is not complete.",
    "Unverified": "The article leaves this unverified, or required material is absent from the current stored summary. This is distinct from zero, absence or safety.",
    "Review incomplete": "Existing content review remains incomplete.",
    "Not reported": "Not reported within the stored material actually read; not extended to the entire primary paper.",
    "Inaccessible": "Means an actual access failure. Access not attempted here is not assigned this state.",
    "Not applicable": "Not used as a substitute for an evidence gap.",
    "Conflicting data": "Requires an observed disagreement under the same comparison criteria; not automatically judged in this production.",
    "Insufficient evidence for the conditions": "Marks a gap in additional material required by the selected conditions; not a new efficacy grade."
  },
  "requirements": [
    {
      "item_id": "N01",
      "question_type": "Evidence condition",
      "question": "Selected isolated-component question and original grade",
      "needed": "Mankai or green-tea wording, note and grade, and the parent dietary verdict",
      "role": "Required",
      "role_reason": "This applied condition distinguishes Mankai or green-tea wording, note and grade, and the parent dietary verdict to connect required material for the selected question with currently available material.",
      "application_exception": "Stay within the stored-summary scope of the selected diet, population, endpoint and duration. Do not substitute figures from other diets, trials or endpoints, or unread external material.",
      "criterion": "Original material and analysis scope for this requirement must be provided, with unverified points distinguishable: Mankai or green-tea wording, note and grade, and the parent dietary verdict. Stored wording is linked; review of existing content remains incomplete.",
      "basis": "M03 §3.1, §3.2.1–3.2.4 question-clarification principles; detailed separation rules are internally designed; M04 §4.5, §4.6.3; limits of this material conversion follow the review scope and internal design",
      "condition_origin": "Production conditions for turning the preserved account into a table; existing content review remains incomplete, and this is not a record of running an official tool or completing content review",
      "proposed_research": "Record updates distinguishing isolated-component and bundled-diet questions. This is a proposal; no new investigation, calculation or trial is conducted here."
    },
    {
      "item_id": "N02",
      "question_type": "Evidence condition",
      "question": "Boundary between the bundled diet and component attribution",
      "needed": "Simultaneously changed components, factor separation and isolated comparisons",
      "role": "Required",
      "role_reason": "This applied condition distinguishes Simultaneously changed components, factor separation and isolated comparisons to connect required material for the selected question with currently available material.",
      "application_exception": "Stay within the stored-summary scope of the selected diet, population, endpoint and duration. Do not substitute figures from other diets, trials or endpoints, or unread external material.",
      "criterion": "Original material and analysis scope for this requirement must be provided, with unverified points distinguishable: Simultaneously changed components, factor separation and isolated comparisons. Stored wording is linked; review of existing content remains incomplete.",
      "basis": "M03 §3.1, §3.2.1–3.2.4 question-clarification principles; detailed separation rules are internally designed; M03 §3.2.2–3.2.3; reverse-direction labels and checking adaptations are internally designed; M08 §8.2.2, M15 §15.3.1; internal application",
      "condition_origin": "Production conditions for turning the preserved account into a table; existing content review remains incomplete, and this is not a record of running an official tool or completing content review",
      "proposed_research": "Propose follow-up research separating component attribution from the bundled pattern. No product or diet instructions are produced. This is a proposal; no new investigation, calculation or trial is conducted here."
    },
    {
      "item_id": "N03",
      "question_type": "Evidence condition",
      "question": "Physical activity common to all three groups",
      "needed": "Common exposures in all groups and actual implementation",
      "role": "Required",
      "role_reason": "This applied condition distinguishes Common exposures in all groups and actual implementation to connect required material for the selected question with currently available material.",
      "application_exception": "Stay within the stored-summary scope of the selected diet, population, endpoint and duration. Do not substitute figures from other diets, trials or endpoints, or unread external material.",
      "criterion": "Original material and analysis scope for this requirement must be provided, with unverified points distinguishable: Common exposures in all groups and actual implementation. Stored wording is linked; review of existing content remains incomplete.",
      "basis": "M03 §3.2.2–3.2.3; Reverse-direction labels and assessment adaptation are Chamgap design; M03 §3.2.3 and M08 §8.2.2–8.2.3; Chamgap application",
      "condition_origin": "Production conditions for turning the preserved account into a table; existing content review remains incomplete, and this is not a record of running an official tool or completing content review",
      "proposed_research": "Propose follow-up material distinguishing common exposures from dietary differences. Exercise instructions are not written. This is a proposal; no new investigation, calculation or trial is conducted here."
    },
    {
      "item_id": "N04",
      "question_type": "Evidence condition",
      "question": "Walnuts common to both MED groups",
      "needed": "Common and different food exposures by group",
      "role": "Required",
      "role_reason": "This applied condition distinguishes Common and different food exposures by group to connect required material for the selected question with currently available material.",
      "application_exception": "Stay within the stored-summary scope of the selected diet, population, endpoint and duration. Do not substitute figures from other diets, trials or endpoints, or unread external material.",
      "criterion": "Original material and analysis scope for this requirement must be provided, with unverified points distinguishable: Common and different food exposures by group. Stored wording is linked; review of existing content remains incomplete.",
      "basis": "M03 §3.2.2–3.2.3; reverse-direction markers and test adaptation are in-house design; M03 §3.2.3, M08 §8.2.2–8.2.3; in-house application; M04 §4.6.3, M15 §15.3.1–15.3.3; status separation is in-house design",
      "condition_origin": "Production conditions for turning the preserved account into a table; existing content review remains incomplete, and this is not a record of running an official tool or completing content review",
      "proposed_research": "Propose follow-up material disclosing common foods and different components. No intake guidance is provided. This is a proposal; no new investigation, calculation or trial is conducted here."
    },
    {
      "item_id": "N05",
      "question_type": "Evidence condition",
      "question": "Study exposures added in green-MED",
      "needed": "Simultaneous planned and actual green-tea, Mankai and meat-restriction exposures",
      "role": "Required",
      "role_reason": "This applied condition distinguishes Simultaneous planned and actual green-tea, Mankai and meat-restriction exposures to connect required material for the selected question with currently available material.",
      "application_exception": "Stay within the stored-summary scope of the selected diet, population, endpoint and duration. Do not substitute figures from other diets, trials or endpoints, or unread external material.",
      "criterion": "Original material and analysis scope for this requirement must be provided, with unverified points distinguishable: Simultaneous planned and actual green-tea, Mankai and meat-restriction exposures. Stored wording is linked; review of existing content remains incomplete.",
      "basis": "M03 §3.2.2–3.2.3; reverse-direction labels and checking adaptations are internally designed; M03 §3.2.3, M08 §8.2.2–8.2.3; internal application; M03 §3.2.1–3.2.4; dose, duration and effect-modification details are internally designed",
      "condition_origin": "Production conditions for turning the preserved account into a table; existing content review remains incomplete, and this is not a record of running an official tool or completing content review",
      "proposed_research": "Propose follow-up material separating planned from actual component exposures. No dose or energy conversions are produced. This is a proposal; no new investigation, calculation or trial is conducted here."
    },
    {
      "item_id": "N06",
      "question_type": "Evidence condition",
      "question": "Direct material for Mankai alone",
      "needed": "Isolated formulation, comparator, population, outcome and denominators",
      "role": "Required",
      "role_reason": "This applied condition distinguishes Isolated formulation, comparator, population, outcome and denominators to connect required material for the selected question with currently available material.",
      "application_exception": "Stay within the stored-summary scope of the selected diet, population, endpoint and duration. Do not substitute figures from other diets, trials or endpoints, or unread external material.",
      "criterion": "Original material and analysis scope for this requirement must be provided, with unverified points distinguishable: Isolated formulation, comparator, population, outcome and denominators. Stored wording is linked; review of existing content remains incomplete.",
      "basis": "M03 §3.1, §3.2.1–3.2.4 question-clarification principles; detailed separation rules are internally designed; M04 §4.6.1–4.6.2 distinctions between studies and reports; cohort and outcome linkage is internal application; M03 §3.2.2–3.2.3; reverse-direction markers and test adaptation are internally designed; M15 §15.3.1–15.3.3; internal application",
      "condition_origin": "Production conditions for turning the preserved account into a table; existing content review remains incomplete, and this is not a record of running an official tool or completing content review",
      "proposed_research": "Propose follow-up research separating the isolated-component study specification. No hypothetical reports or effects are created. This is a proposal; no new investigation, calculation or trial is conducted here."
    },
    {
      "item_id": "N07",
      "question_type": "Evidence condition",
      "question": "Direct material for green tea alone",
      "needed": "Isolated formulation, comparator, population, outcome and denominators",
      "role": "Required",
      "role_reason": "This applied condition distinguishes Isolated formulation, comparator, population, outcome and denominators to connect required material for the selected question with currently available material.",
      "application_exception": "Stay within the stored-summary scope of the selected diet, population, endpoint and duration. Do not substitute figures from other diets, trials or endpoints, or unread external material.",
      "criterion": "Original material and analysis scope for this requirement must be provided, with unverified points distinguishable: Isolated formulation, comparator, population, outcome and denominators. Stored wording is linked; review of existing content remains incomplete.",
      "basis": "M03 §3.1, §3.2.1–3.2.4 question-clarification principles; detailed separation rules are internally designed; M04 §4.6.1–4.6.2 distinctions between studies and reports; cohort and outcome linkage is internal application; M03 §3.2.2–3.2.3; reverse-direction markers and test adaptation are internally designed; M15 §15.3.1–15.3.3; internal application",
      "condition_origin": "Production conditions for turning the preserved account into a table; existing content review remains incomplete, and this is not a record of running an official tool or completing content review",
      "proposed_research": "Propose follow-up research distinguishing isolated components from bundled diets. No intake or treatment instructions are given. This is a proposal; no new investigation, calculation or trial is conducted here."
    },
    {
      "item_id": "N08",
      "question_type": "Evidence condition",
      "question": "Actual population of the parent trial",
      "needed": "Abdominal obesity or dyslipidemia, eligibility and denominators",
      "role": "Required",
      "role_reason": "This applied condition distinguishes Abdominal obesity or dyslipidemia, eligibility and denominators to connect required material for the selected question with currently available material.",
      "application_exception": "Stay within the stored-summary scope of the selected diet, population, endpoint and duration. Do not substitute figures from other diets, trials or endpoints, or unread external material.",
      "criterion": "Original material and analysis scope for this requirement must be provided, with unverified points distinguishable: Abdominal obesity or dyslipidemia, eligibility and denominators. Stored wording is linked; review of existing content remains incomplete.",
      "basis": "M03 §3.2.1; detailed population conditions are internally designed. M08 Table 8.2.a, M15 §15.3 and M19 §19.1.2–19.2.4; design-specific adaptations are internally designed.",
      "condition_origin": "Production conditions for turning the preserved account into a table; existing content review remains incomplete, and this is not a record of running an official tool or completing content review",
      "proposed_research": "Propose follow-up material distinguishing populations and application boundaries for isolated and bundled questions. This is a proposal; no new investigation, calculation or trial is conducted here."
    },
    {
      "item_id": "N09",
      "question_type": "Evidence condition",
      "question": "Different conventional-MED and healthy-diet-guidance contrasts",
      "needed": "Three-group exposures, denominators and comparison specifications",
      "role": "Required",
      "role_reason": "This applied condition distinguishes Three-group exposures, denominators and comparison specifications to connect required material for the selected question with currently available material.",
      "application_exception": "Stay within the stored-summary scope of the selected diet, population, endpoint and duration. Do not substitute figures from other diets, trials or endpoints, or unread external material.",
      "criterion": "Original material and analysis scope for this requirement must be provided, with unverified points distinguishable: Three-group exposures, denominators and comparison specifications. Stored wording is linked; review of existing content remains incomplete.",
      "basis": "M03 §3.2.2–3.2.3; reverse-direction markers and test adaptation are internally designed; M08 §8.2.2, M15 §15.3.1; internal application; M15 §15.3.1–15.3.3; internal application",
      "condition_origin": "Production conditions for turning the preserved account into a table; existing content review remains incomplete, and this is not a record of running an official tool or completing content review",
      "proposed_research": "Propose follow-up material with disclosed comparator-specific study specifications. This is a proposal; no new investigation, calculation or trial is conducted here."
    },
    {
      "item_id": "N10",
      "question_type": "Evidence condition",
      "question": "Intrahepatic-fat MRS and isolated-component results",
      "needed": "Proton-MRS definitions, units, time points and directness",
      "role": "Required",
      "role_reason": "This applied condition distinguishes Proton-MRS definitions, units, time points and directness to connect required material for the selected question with currently available material.",
      "application_exception": "Stay within the stored-summary scope of the selected diet, population, endpoint and duration. Do not substitute figures from other diets, trials or endpoints, or unread external material.",
      "criterion": "Original material and analysis scope for this requirement must be provided, with unverified points distinguishable: Proton-MRS definitions, units, time points and directness. Stored wording is linked; review of existing content remains incomplete.",
      "basis": "M03 §3.2.4 and M15 §15.3.1–15.3.3; Question-specific outcome adaptation is Chamgap design; M08 Table 8.2.a and M03 §3.2.4; Chamgap application; M03 §3.2.4; Chamgap interpretation boundary",
      "condition_origin": "Production conditions for turning the preserved account into a table; existing content review remains incomplete, and this is not a record of running an official tool or completing content review",
      "proposed_research": "Propose follow-up material separating measurement methods from component attribution. This is a proposal; no new investigation, calculation or trial is conducted here."
    },
    {
      "item_id": "N11",
      "question_type": "Evidence condition",
      "question": "Proportional reductions and absolute or between-group effects",
      "needed": "Group proportional changes, denominators and estimates",
      "role": "Required",
      "role_reason": "This applied condition distinguishes Group proportional changes, denominators and estimates to connect required material for the selected question with currently available material.",
      "application_exception": "Stay within the stored-summary scope of the selected diet, population, endpoint and duration. Do not substitute figures from other diets, trials or endpoints, or unread external material.",
      "criterion": "Original material and analysis scope for this requirement must be provided, with unverified points distinguishable: Group proportional changes, denominators and estimates. Stored wording is linked; review of existing content remains incomplete.",
      "basis": "M03 §3.2.4, M15 §15.3.1–15.3.3; question-specific outcome adaptations are internally designed; M08 Table 8.2.a, M15 §15.3, M19 §19.1.2–19.2.4; design-specific adaptations are internally designed; M08 §8.2.2, M15 §15.3.1; internal application; M15 §15.3.1–15.3.3; internal application",
      "condition_origin": "Production conditions for turning the preserved account into a table; existing content review remains incomplete, and this is not a record of running an official tool or completing content review",
      "proposed_research": "Propose follow-up material separating units and scope of reported estimates. No new calculations are produced. This is a proposal; no new investigation, calculation or trial is conducted here."
    },
    {
      "item_id": "N12",
      "question_type": "Evidence condition",
      "question": "Weight-adjusted P values and causal component attribution",
      "needed": "Adjusted models, contrasts, weight changes and effects",
      "role": "Required",
      "role_reason": "This applied condition distinguishes Adjusted models, contrasts, weight changes and effects to connect required material for the selected question with currently available material.",
      "application_exception": "Stay within the stored-summary scope of the selected diet, population, endpoint and duration. Do not substitute figures from other diets, trials or endpoints, or unread external material.",
      "criterion": "Original material and analysis scope for this requirement must be provided, with unverified points distinguishable: Adjusted models, contrasts, weight changes and effects. Stored wording is linked; review of existing content remains incomplete.",
      "basis": "M08 §8.2.2, M15 §15.3.1; internal application; M15 §15.3.1–15.3.3; internal application; M03 §3.2.3, M08 §8.2.2–8.2.3; internal application",
      "condition_origin": "Production conditions for turning the preserved account into a table; existing content review remains incomplete, and this is not a record of running an official tool or completing content review",
      "proposed_research": "Propose follow-up research separating weight change from component attribution. This is a proposal; no new investigation, calculation or trial is conducted here."
    },
    {
      "item_id": "N13",
      "question_type": "Evidence condition",
      "question": "Historical wording of a small standardized effect",
      "needed": "Original standardized estimates, denominators and interpretation specifications",
      "role": "Required",
      "role_reason": "This applied condition distinguishes Original standardized estimates, denominators and interpretation specifications to connect required material for the selected question with currently available material.",
      "application_exception": "Stay within the stored-summary scope of the selected diet, population, endpoint and duration. Do not substitute figures from other diets, trials or endpoints, or unread external material.",
      "criterion": "Original material and analysis scope for this requirement must be provided, with unverified points distinguishable: Original standardized estimates, denominators and interpretation specifications. Stored wording is linked; review of existing content remains incomplete.",
      "basis": "M15 §15.3.1–15.3.3; Chamgap adaptation; M04 §4.5, §4.6.3; limitations of the current material conversion follow the review scope and Chamgap design",
      "condition_origin": "Production conditions for turning the preserved account into a table; existing content review remains incomplete, and this is not a record of running an official tool or completing content review",
      "proposed_research": "Propose follow-up records separating reported effects from the historical scope of verdict interpretation. This is a proposal; no new investigation, calculation or trial is conducted here."
    },
    {
      "item_id": "N14",
      "question_type": "Evidence condition",
      "question": "Retention and eligible MRS have different denominators",
      "needed": "Randomization, retention, imaging eligibility and group missingness",
      "role": "Required",
      "role_reason": "This applied condition distinguishes Randomization, retention, imaging eligibility and group missingness to connect required material for the selected question with currently available material.",
      "application_exception": "Stay within the stored-summary scope of the selected diet, population, endpoint and duration. Do not substitute figures from other diets, trials or endpoints, or unread external material.",
      "criterion": "Original material and analysis scope for this requirement must be provided, with unverified points distinguishable: Randomization, retention, imaging eligibility and group missingness. Stored wording is linked; review of existing content remains incomplete.",
      "basis": "M08 Table 8.2.a, M15 §15.3 and M19 §19.1.2–19.2.4; Design-specific adaptation is Chamgap design; M08 §8.2.2 and M15 §15.3.1; Chamgap application",
      "condition_origin": "Production conditions for turning the preserved account into a table; existing content review remains incomplete, and this is not a record of running an official tool or completing content review",
      "proposed_research": "Propose follow-up material distinguishing retention from imaging-analysis eligibility. No new count or rate calculations are produced. This is a proposal; no new investigation, calculation or trial is conducted here."
    },
    {
      "item_id": "N15",
      "question_type": "Evidence condition",
      "question": "Missing imaging, analysis populations and sensitivity analyses",
      "needed": "Missing-data handling, ITT or PP, selection and estimate stability",
      "role": "Required",
      "role_reason": "This applied condition distinguishes Missing-data handling, ITT or PP, selection and estimate stability to connect required material for the selected question with currently available material.",
      "application_exception": "Stay within the stored-summary scope of the selected diet, population, endpoint and duration. Do not substitute figures from other diets, trials or endpoints, or unread external material.",
      "criterion": "Original material and analysis scope for this requirement must be provided, with unverified points distinguishable: Missing-data handling, ITT or PP, selection and estimate stability. Stored wording is linked; review of existing content remains incomplete.",
      "basis": "M08 Table 8.2.a, M15 §15.3 and M19 §19.1.2–19.2.4; Design-specific adaptation is Chamgap design; M08 §8.2.2 and M15 §15.3.1; Chamgap application",
      "condition_origin": "Production conditions for turning the preserved account into a table; existing content review remains incomplete, and this is not a record of running an official tool or completing content review",
      "proposed_research": "Propose follow-up material distinguishing missingness from analysis specifications. This is a proposal; no new investigation, calculation or trial is conducted here."
    },
    {
      "item_id": "N16",
      "question_type": "Evidence condition",
      "question": "Randomization and assessment masking",
      "needed": "Allocation, concealment, MRS reading, contact and expectations",
      "role": "Required",
      "role_reason": "This applied condition distinguishes Allocation, concealment, MRS reading, contact and expectations to connect required material for the selected question with currently available material.",
      "application_exception": "Stay within the stored-summary scope of the selected diet, population, endpoint and duration. Do not substitute figures from other diets, trials or endpoints, or unread external material.",
      "criterion": "Original material and analysis scope for this requirement must be provided, with unverified points distinguishable: Allocation, concealment, MRS reading, contact and expectations. Stored wording is linked; review of existing content remains incomplete.",
      "basis": "M08 §8.1–8.2.3; internal application; M08 Table 8.2.a, M03 §3.2.4; internal application",
      "condition_origin": "Production conditions for turning the preserved account into a table; existing content review remains incomplete, and this is not a record of running an official tool or completing content review",
      "proposed_research": "Propose follow-up material disclosing lifestyle exposures and imaging-assessment conditions. This is a proposal; no new investigation, calculation or trial is conducted here."
    },
    {
      "item_id": "N17",
      "question_type": "Evidence condition",
      "question": "Actual diets, activity and other concurrent exposures",
      "needed": "Food, weight, activity and management adherence material",
      "role": "Required",
      "role_reason": "This applied condition distinguishes Food, weight, activity and management adherence material to connect required material for the selected question with currently available material.",
      "application_exception": "Stay within the stored-summary scope of the selected diet, population, endpoint and duration. Do not substitute figures from other diets, trials or endpoints, or unread external material.",
      "criterion": "Original material and analysis scope for this requirement must be provided, with unverified points distinguishable: Food, weight, activity and management adherence material. Stored wording is linked; review of existing content remains incomplete.",
      "basis": "M03 §3.2.3, M08 §8.2.2–8.2.3; our own application; M08 §8.2.2, M15 §15.3.1; our own application",
      "condition_origin": "Production conditions for turning the preserved account into a table; existing content review remains incomplete, and this is not a record of running an official tool or completing content review",
      "proposed_research": "Propose follow-up material distinguishing common from different exposures. No diet or weight-management instructions are given. This is a proposal; no new investigation, calculation or trial is conducted here."
    },
    {
      "item_id": "N18",
      "question_type": "Evidence condition",
      "question": "Registration identifier and access to actual plans",
      "needed": "Original registration identifier, protocol, SAP and changes",
      "role": "Required",
      "role_reason": "This applied condition distinguishes Original registration identifier, protocol, SAP and changes to connect required material for the selected question with currently available material.",
      "application_exception": "Stay within the stored-summary scope of the selected diet, population, endpoint and duration. Do not substitute figures from other diets, trials or endpoints, or unread external material.",
      "criterion": "Original material and analysis scope for this requirement must be provided, with unverified points distinguishable: Original registration identifier, protocol, SAP and changes. Stored wording is linked; review of existing content remains incomplete.",
      "basis": "Data collection and selection principles in M04 §4.5–4.6; separation of access from reading and the hyperlink contract are internally designed; M08 Table 8.2.a, M04 §4.6.3; internal application; M04 §4.5, §4.6.3; limits of this material conversion reflect the review scope and internal design",
      "condition_origin": "Production conditions for turning the preserved account into a table; existing content review remains incomplete, and this is not a record of running an official tool or completing content review",
      "proposed_research": "Propose follow-up material distinguishing the preserved identifier from actual plan access. This is a proposal; no new investigation, calculation or trial is conducted here."
    },
    {
      "item_id": "N19",
      "question_type": "Evidence condition",
      "question": "Multiple contrasts and analysis hierarchy",
      "needed": "Plans for three groups, time points, outcomes and subgroup analyses",
      "role": "Required",
      "role_reason": "This applied condition distinguishes Plans for three groups, time points, outcomes and subgroup analyses to connect required material for the selected question with currently available material.",
      "application_exception": "Stay within the stored-summary scope of the selected diet, population, endpoint and duration. Do not substitute figures from other diets, trials or endpoints, or unread external material.",
      "criterion": "Original material and analysis scope for this requirement must be provided, with unverified points distinguishable: Plans for three groups, time points, outcomes and subgroup analyses. Stored wording is linked; review of existing content remains incomplete.",
      "basis": "M08 Table 8.2.a, M04 §4.6.3; internal application; M08 §8.2.2, M15 §15.3.1; internal application; M04 §4.6.3, M15 §15.3.1–15.3.3; status separation is internally designed",
      "condition_origin": "Production conditions for turning the preserved account into a table; existing content review remains incomplete, and this is not a record of running an official tool or completing content review",
      "proposed_research": "Propose follow-up material distinguishing all contrasts from component questions. This is a proposal; no new investigation, calculation or trial is conducted here."
    },
    {
      "item_id": "N20",
      "question_type": "Evidence condition",
      "question": "The same trial and absence of linked isolated-component replication",
      "needed": "Relationships among reports, groups, time points and independent trials",
      "role": "Required",
      "role_reason": "This applied condition distinguishes Relationships among reports, groups, time points and independent trials to connect required material for the selected question with currently available material.",
      "application_exception": "Stay within the stored-summary scope of the selected diet, population, endpoint and duration. Do not substitute figures from other diets, trials or endpoints, or unread external material.",
      "criterion": "Original material and analysis scope for this requirement must be provided, with unverified points distinguishable: Relationships among reports, groups, time points and independent trials. Stored wording is linked; review of existing content remains incomplete.",
      "basis": "Study/report distinction in M04 §4.6.1–4.6.2; Cohort/outcome linkage is Chamgap application; M04 §4.6.1–4.6.2 and M15 §15.3.1; Chamgap application",
      "condition_origin": "Production conditions for turning the preserved account into a table; existing content review remains incomplete, and this is not a record of running an official tool or completing content review",
      "proposed_research": "Propose separate research with the same component study specification. No new totals or independence certification are produced. This is a proposal; no new investigation, calculation or trial is conducted here."
    },
    {
      "item_id": "N21",
      "question_type": "Evidence condition",
      "question": "18 months and clinical liver-disease events",
      "needed": "Imaging surrogates, persistence and clinical outcomes",
      "role": "Required",
      "role_reason": "This applied condition distinguishes Imaging surrogates, persistence and clinical outcomes to connect required material for the selected question with currently available material.",
      "application_exception": "Stay within the stored-summary scope of the selected diet, population, endpoint and duration. Do not substitute figures from other diets, trials or endpoints, or unread external material.",
      "criterion": "Original material and analysis scope for this requirement must be provided, with unverified points distinguishable: Imaging surrogates, persistence and clinical outcomes. Stored wording is linked; review of existing content remains incomplete.",
      "basis": "M03 §3.2.1–3.2.4; dose, persistence and effect-modification details are internally designed; M03 §3.2.4; internally defined extension boundaries; M04 §4.5, §4.6.3; current material-conversion limits follow the review scope and internal design",
      "condition_origin": "Production conditions for turning the preserved account into a table; existing content review remains incomplete, and this is not a record of running an official tool or completing content review",
      "proposed_research": "Propose follow-up research distinguishing imaging from clinical outcomes. This is a proposal; no new investigation, calculation or trial is conducted here."
    },
    {
      "item_id": "N22",
      "question_type": "Evidence condition",
      "question": "Application to other populations, foods and products",
      "needed": "Direct material by eligibility, disease, formulation and exposure",
      "role": "Required",
      "role_reason": "This applied condition distinguishes Direct material by eligibility, disease, formulation and exposure to connect required material for the selected question with currently available material.",
      "application_exception": "Stay within the stored-summary scope of the selected diet, population, endpoint and duration. Do not substitute figures from other diets, trials or endpoints, or unread external material.",
      "criterion": "Original material and analysis scope for this requirement must be provided, with unverified points distinguishable: Direct material by eligibility, disease, formulation and exposure. Stored wording is linked; review of existing content remains incomplete.",
      "basis": "M03 §3.2.1; detailed population conditions are our own design; M03 §3.2.2–3.2.3; reverse-direction labels and test adaptations are our own design; M03 §3.2.1–3.2.4; dose, duration and effect-modification details are our own design",
      "condition_origin": "Production conditions for turning the preserved account into a table; existing content review remains incomplete, and this is not a record of running an official tool or completing content review",
      "proposed_research": "Propose separate material for questions with different populations or products. No intake or treatment instructions are given. This is a proposal; no new investigation, calculation or trial is conducted here."
    },
    {
      "item_id": "N23",
      "question_type": "Evidence condition",
      "question": "Mixed funding and product-related roles",
      "needed": "Original funding, advisory, product-support, employee-authorship and COI material",
      "role": "Required",
      "role_reason": "This applied condition distinguishes Original funding, advisory, product-support, employee-authorship and COI material to connect required material for the selected question with currently available material.",
      "application_exception": "Stay within the stored-summary scope of the selected diet, population, endpoint and duration. Do not substitute figures from other diets, trials or endpoints, or unread external material.",
      "criterion": "Original material and analysis scope for this requirement must be provided, with unverified points distinguishable: Original funding, advisory, product-support, employee-authorship and COI material. Stored wording is linked; review of existing content remains incomplete.",
      "basis": "Chamgap's own conditions for independence and attribution. The official methodological sections used in this example do not validate every detail of these items.",
      "condition_origin": "Production conditions for turning the preserved account into a table; existing content review remains incomplete, and this is not a record of running an official tool or completing content review",
      "proposed_research": "Propose follow-up material distinguishing support types from roles. This is a proposal; no new investigation, calculation or trial is conducted here."
    },
    {
      "item_id": "N24",
      "question_type": "Harm-information gaps supplementing the efficacy table",
      "question": "Safety and gaps concerning individuals and products",
      "needed": "Harm-event collection, exposures, denominators and discontinuation",
      "role": "Supplementary",
      "role_reason": "This applied condition distinguishes Harm-event collection, exposures, denominators and discontinuation to connect required material for the selected question with currently available material.",
      "application_exception": "Address safety-material gaps for the selected subclaim. Diet, isolated-component or imaging findings, or parent safety wording do not determine safety or create harm incidence rates or new use instructions.",
      "criterion": "Original material and analysis scope for this requirement must be provided, with unverified points distinguishable: Harm-event collection, exposures, denominators and discontinuation. Stored wording is linked; review of existing content remains incomplete.",
      "basis": "M19 §19.1.2–19.2.4; internal application. M19 §19.1.2–19.2.4; detailed distinctions are internally designed. M19 §19.2 covers design-specific harm questions; detailed temporal relationships are internally designed. M19 §19.2.2–19.2.4 and M03 §3.2.3; internal application. M19 §19.1.2–19.2.4; internal application. M19 §19.2.2–19.2.4 considers design; detailed confounding records are internally designed. M19 §19.1.2–19.2.4 and M04 §4.6.3; internal application. M19 §19.1.2–19.2.4; internal application. Interpretation boundaries are internally defined, informed by M19 principles; no official causality tool is executed.",
      "condition_origin": "Production conditions for turning the preserved account into a table; existing content review remains incomplete, and this is not a record of running an official tool or completing content review",
      "proposed_research": "Propose follow-up material directly collecting safety information. No diet, liver-disease or weight-management instructions are provided. This is a proposal; no new investigation, calculation or trial is conducted here."
    },
    {
      "item_id": "N25",
      "question_type": "Evidence condition",
      "question": "Original grades, axes, languages, dates and corrections",
      "needed": "Separation of parent C with 46 points, subclaim ? and historical original values",
      "role": "Required",
      "role_reason": "This applied condition distinguishes Separation of parent C with 46 points, subclaim ? and historical original values to connect required material for the selected question with currently available material.",
      "application_exception": "Stay within the stored-summary scope of the selected diet, population, endpoint and duration. Do not substitute figures from other diets, trials or endpoints, or unread external material.",
      "criterion": "Original material and analysis scope for this requirement must be provided, with unverified points distinguishable: Separation of parent C with 46 points, subclaim ? and historical original values. Stored wording is linked; review of existing content remains incomplete.",
      "basis": "M04 §4.5, §4.6.3; limits of this material conversion follow the review scope and internal design; M03 §3.1, §3.2.1–3.2.4 question-clarification principles; detailed separation rules are internally designed",
      "condition_origin": "Production conditions for turning the preserved account into a table; existing content review remains incomplete, and this is not a record of running an official tool or completing content review",
      "proposed_research": "Update records distinguishing original values, production dates and correction events. This is a proposal; no new investigation, calculation or trial is conducted here."
    },
    {
      "item_id": "N26",
      "question_type": "Evidence condition",
      "question": "Historical verification and actual summary reading",
      "needed": "Scope of historical review, unread material and links",
      "role": "Required",
      "role_reason": "This applied condition distinguishes Scope of historical review, unread material and links to connect required material for the selected question with currently available material.",
      "application_exception": "Stay within the stored-summary scope of the selected diet, population, endpoint and duration. Do not substitute figures from other diets, trials or endpoints, or unread external material.",
      "criterion": "Original material and analysis scope for this requirement must be provided, with unverified points distinguishable: Scope of historical review, unread material and links. Stored wording is linked; review of existing content remains incomplete.",
      "basis": "M04 §4.5–4.6 covers material collection and selection; distinctions between access and reading and hyperlink specifications are internally designed. M04 §4.6.1–4.6.2 distinguishes studies and reports; cohort and outcome linkage is an internal application. M04 §4.5 and §4.6.3; current evidence-conversion limits reflect review scope and internal design.",
      "condition_origin": "Production conditions for turning the preserved account into a table; existing content review remains incomplete, and this is not a record of running an official tool or completing content review",
      "proposed_research": "Update content distinguishing history from actual access events. This is a proposal; no new investigation, calculation or trial is conducted here."
    }
  ]
}