{ "schema_version": "chamgap-public-criteria-1.0", "title": "DDMP lactic-acid-bacteria beverage × Moisture change at weeks 4 and 8", "language": "en", "translation_date": "2026-10-14", "criteria_version": "1.0", "criteria_date": "2026-10-06", "condition_origin": "Chamgap's own application conditions", "method_sources": [ { "id": "M03", "version": "Cochrane Handbook 6.5 (2024), chapter updated 2023-08", "url": "https://www.cochrane.org/authors/handbooks-and-manuals/handbook/current/chapter-03", "section": "§3.1, §3.2.1–3.2.3, MECIR C5/C7/C13", "official_principle": "Clearly record the question, eligibility conditions and reasons for changes, and distinguish variations in interventions.", "review_level": "Preserved method HTML copies; no current method-content re-review or official tool execution" }, { "id": "M04", "version": "Cochrane Handbook 6.5.1 (2025), chapter updated 2025-03", "url": "https://www.cochrane.org/authors/handbooks-and-manuals/handbook/current/chapter-04", "section": "§4.5, §4.6.1–4.6.3, MECIR C42", "official_principle": "Distinguish studies from reports and link them; do not omit a study solely because results are unreported.", "review_level": "Preserved method HTML copies; no current method-content re-review or official tool execution" }, { "id": "M08", "version": "Cochrane Handbook 6.5 (2024), chapter updated 2019-10", "url": "https://www.cochrane.org/authors/handbooks-and-manuals/handbook/current/chapter-08", "section": "§8.1–8.2.3, Table 8.2.a", "official_principle": "Define the outcome and effect of interest, then examine randomization, deviations, missing data, measurement and selective reporting.", "review_level": "Preserved method HTML copies; no current method-content re-review or official tool execution" }, { "id": "M15", "version": "Cochrane Handbook 6.5 (2024), chapter updated 2023-08", "url": "https://www.cochrane.org/authors/handbooks-and-manuals/handbook/current/chapter-15", "section": "§15.2.4, §15.3.1–15.3.3", "official_principle": "Distinguish effect estimates, intervals, importance and applicability. Sample size alone does not determine precision.", "review_level": "Preserved method HTML copies; no current method-content re-review or official tool execution" }, { "id": "M19", "version": "Cochrane Handbook 6.5 (2024), chapter updated 2019-10", "url": "https://www.cochrane.org/authors/handbooks-and-manuals/handbook/current/chapter-19", "section": "§19.1.2, §19.2.1–19.2.4", "official_principle": "Harm questions may require different designs, populations and follow-up from efficacy questions. Case reports do not establish incidence rates.", "review_level": "Preserved method HTML copies; no current method-content re-review or official tool execution" } ], "status_dictionary": { "Met": "Status for necessary evidence confirmed after existing content review. No completion is declared in the current presentation.", "Partly verified": "Some information in the stored summary is linked into the table. External comparison/content review is not complete.", "Unverified": "The article leaves this unverified, or required material is absent from the current stored summary. This is distinct from zero, absence or safety.", "Review incomplete": "Existing content review remains incomplete.", "Not reported": "Not reported within the stored material actually read; not extended to the entire primary paper.", "Inaccessible": "Means an actual access failure. Access not attempted here is not assigned this state.", "Not applicable": "Not used as a substitute for an evidence gap.", "Conflicting data": "Requires an observed disagreement under the same comparison criteria; not automatically judged in this production.", "Insufficient evidence for the conditions": "Marks a gap in additional material required by the selected conditions; not a new efficacy grade." }, "requirements": [ { "item_id": "N01", "question_type": "Evidence condition", "question": "Selected intermediate-visit question and original grade", "needed": "Distinction between the original wording and grade for weeks 4 and 8 and the parent final-visit verdict", "role": "Required", "role_reason": "This item distinguishes distinction between the original wording and grade for weeks 4 and 8 and the parent final-visit verdict to connect the evidence needed for the selected question with the evidence currently available.", "application_exception": "Limited to the stored summary for the selected formulation, population, endpoint and period. 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No new investigation, calculation or trial was performed." }, { "item_id": "N07", "question_type": "Evidence condition", "question": "12-week exposure and adherence", "needed": "Study exposure, consumption records, group-specific adherence and withdrawal criteria", "role": "Required", "role_reason": "This item distinguishes study exposure, consumption records, group-specific adherence and withdrawal criteria to connect the evidence needed for the selected question with the evidence currently available.", "application_exception": "Limited to the stored summary for the selected formulation, population, endpoint and period. It does not substitute for numbers from other formulations/trials/endpoints or unread external material.", "criterion": "Relevant source data and analysis details for study exposure, consumption records, group-specific adherence and withdrawal criteria must be provided, with unverified points identified. 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No new investigation, calculation or trial was performed." }, { "item_id": "N12", "question_type": "Evidence condition", "question": "Final week-12 absolute moisture values", "needed": "Absolute values, units and P for the prespecified final primary endpoint", "role": "Required", "role_reason": "This item distinguishes absolute values, units and P for the prespecified final primary endpoint to connect the evidence needed for the selected question with the evidence currently available.", "application_exception": "Limited to the stored summary for the selected formulation, population, endpoint and period. It does not substitute for numbers from other formulations/trials/endpoints or unread external material.", "criterion": "Relevant source data and analysis details for absolute values, units and P for the prespecified final primary endpoint must be provided, with unverified points identified. 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No new investigation, calculation or trial was performed." }, { "item_id": "N18", "question_type": "Evidence condition", "question": "Withdrawal, missing data and analysis exclusions", "needed": "Reasons for withdrawal, missing data, group-specific effects and handling", "role": "Required", "role_reason": "This item distinguishes reasons for withdrawal, missing data, group-specific effects and handling to connect the evidence needed for the selected question with the evidence currently available.", "application_exception": "Limited to the stored summary for the selected formulation, population, endpoint and period. It does not substitute for numbers from other formulations/trials/endpoints or unread external material.", "criterion": "Relevant source data and analysis details for reasons for withdrawal, missing data, group-specific effects and handling must be provided, with unverified points identified. 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No new investigation, calculation or trial was performed." }, { "item_id": "N20", "question_type": "Evidence condition", "question": "UMIN identifier and reading of prespecified plans", "needed": "Actual verification scope for registration, protocol, SAP and change history", "role": "Required", "role_reason": "This item distinguishes actual verification scope for registration, protocol, SAP and change history to connect the evidence needed for the selected question with the evidence currently available.", "application_exception": "Limited to the stored summary for the selected formulation, population, endpoint and period. It does not substitute for numbers from other formulations/trials/endpoints or unread external material.", "criterion": "Relevant source data and analysis details for actual verification scope for registration, protocol, SAP and change history must be provided, with unverified points identified. 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No new investigation, calculation or trial was performed." }, { "item_id": "N21", "question_type": "Evidence condition", "question": "Multiple visits, sites and tests", "needed": "Multiplicity specification for intermediate visits, skin sites and analyses", "role": "Required", "role_reason": "This item distinguishes multiplicity specification for intermediate visits, skin sites and analyses to connect the evidence needed for the selected question with the evidence currently available.", "application_exception": "Limited to the stored summary for the selected formulation, population, endpoint and period. It does not substitute for numbers from other formulations/trials/endpoints or unread external material.", "criterion": "Relevant source data and analysis details for multiplicity specification for intermediate visits, skin sites and analyses must be provided, with unverified points identified. Preserved wording is linked here; review of the existing content is incomplete.", "basis": "M08 Table 8.2.a, M04 §4.6.3; internal application; M04 §4.6.1–4.6.2 distinguishes studies from reports; cohort and outcome linkage is an internal application; M04 §4.6.3, M15 §15.3.1–15.3.3; status separation is internally designed", "condition_origin": "Production conditions for turning the preserved account into a table; existing content review remains incomplete, and this is not a record of running an official tool or completing content review", "proposed_research": "A preserved proposal for follow-up research that distinguishes multiple-visit findings from the final primary endpoint. No new investigation, calculation or trial was performed." }, { "item_id": "N22", "question_type": "Evidence condition", "question": "Concurrent skin care, season and lifestyle", "needed": "Group-specific concurrent exposures, lifestyle, seasonal conditions and moisturizer or other care records", "role": "Required", "role_reason": "This item distinguishes group-specific concurrent exposures, lifestyle, seasonal conditions and moisturizer or other care records to connect the evidence needed for the selected question with the evidence currently available.", "application_exception": "Limited to the stored summary for the selected formulation, population, endpoint and period. It does not substitute for numbers from other formulations/trials/endpoints or unread external material.", "criterion": "Relevant source data and analysis details for group-specific concurrent exposures, lifestyle, seasonal conditions and moisturizer or other care records must be provided, with unverified points identified. Preserved wording is linked here; review of the existing content is incomplete.", "basis": "M03 §3.2.3, M08 §8.2.2–8.2.3; own application; M03 §3.2.2–3.2.3; reverse-direction labels and test adaptations are our own design", "condition_origin": "Production conditions for turning the preserved account into a table; existing content review remains incomplete, and this is not a record of running an official tool or completing content review", "proposed_research": "A preserved proposal for follow-up research that explicitly specifies concurrent conditions. No new investigation, calculation or trial was performed." }, { "item_id": "N23", "question_type": "Evidence condition", "question": "Provision of study and placebo beverages", "needed": "Manufacturer product support and scope of provision", "role": "Required", "role_reason": "This item distinguishes manufacturer product support and scope of provision to connect the evidence needed for the selected question with the evidence currently available.", "application_exception": "Limited to the stored summary for the selected formulation, population, endpoint and period. It does not substitute for numbers from other formulations/trials/endpoints or unread external material.", "criterion": "Relevant source data and analysis details for manufacturer product support and scope of provision must be provided, with unverified points identified. Preserved wording is linked here; review of the existing content is incomplete.", "basis": "Chamgap's own conditions for independence and attribution. The official methodological sections used in this example do not validate every detail of these items.", "condition_origin": "Production conditions for turning the preserved account into a table; existing content review remains incomplete, and this is not a record of running an official tool or completing content review", "proposed_research": "A proposed follow-up trial disclosing support roles; no new investigation, calculation or trial was performed." }, { "item_id": "N24", "question_type": "Evidence condition", "question": "Employee authors and contract organization", "needed": "Author affiliations and roles of the company and contract organization", "role": "Required", "role_reason": "This item distinguishes author affiliations and roles of the company and contract organization to connect the evidence needed for the selected question with the evidence currently available.", "application_exception": "Limited to the stored summary for the selected formulation, population, endpoint and period. It does not substitute for numbers from other formulations/trials/endpoints or unread external material.", "criterion": "Relevant source data and analysis details for author affiliations and roles of the company and contract organization must be provided, with unverified points identified. Preserved wording is linked here; review of the existing content is incomplete.", "basis": "Chamgap's own conditions for independence and attribution. The official methodological sections used in this example do not validate every detail of these items.", "condition_origin": "Production conditions for turning the preserved account into a table; existing content review remains incomplete, and this is not a record of running an official tool or completing content review", "proposed_research": "A preserved proposal for follow-up research that separately discloses company and contract-organization roles. No new investigation, calculation or trial was performed." }, { "item_id": "N25", "question_type": "Evidence condition", "question": "Public funding, writing and publication costs", "needed": "Item-specific reporting of funding, writing and publication support", "role": "Required", "role_reason": "This item distinguishes item-specific reporting of funding, writing and publication support to connect the evidence needed for the selected question with the evidence currently available.", "application_exception": "Limited to the stored summary for the selected formulation, population, endpoint and period. It does not substitute for numbers from other formulations/trials/endpoints or unread external material.", "criterion": "Relevant source data and analysis details for item-specific reporting of funding, writing and publication support must be provided, with unverified points identified. Preserved wording is linked here; review of the existing content is incomplete.", "basis": "Chamgap independence/attribution conditions. The referenced official method sections do not certify every detail of these items; Data collection/selection principles in M04 §4.5–4.6; Access/reading separation and hyperlink rules are Chamgap design", "condition_origin": "Production conditions for turning the preserved account into a table; existing content review remains incomplete, and this is not a record of running an official tool or completing content review", "proposed_research": "A preserved proposal for follow-up research that separately discloses each support category. No new investigation, calculation or trial was performed." }, { "item_id": "N26", "question_type": "Evidence condition", "question": "Same trial and intermediate or final results", "needed": "Report-to-trial, visit, site and denominator relationships and independent replication", "role": "Required", "role_reason": "This item distinguishes report-to-trial, visit, site and denominator relationships and independent replication to connect the evidence needed for the selected question with the evidence currently available.", "application_exception": "Limited to the stored summary for the selected formulation, population, endpoint and period. It does not substitute for numbers from other formulations/trials/endpoints or unread external material.", "criterion": "Relevant source data and analysis details for report-to-trial, visit, site and denominator relationships and independent replication must be provided, with unverified points identified. Preserved wording is linked here; review of the existing content is incomplete.", "basis": "Study/report distinction in M04 §4.6.1–4.6.2; Cohort/outcome linkage is Chamgap application; M04 §4.6.1–4.6.2 and M15 §15.3.1; Chamgap application", "condition_origin": "Production conditions for turning the preserved account into a table; existing content review remains incomplete, and this is not a record of running an official tool or completing content review", "proposed_research": "A preserved proposal for follow-up research that independently compares the same final and intermediate outcome specifications. No new investigation, calculation or trial was performed." }, { "item_id": "N27", "question_type": "Evidence condition", "question": "Persistence and other formulations or skin outcomes", "needed": "Distinction between intermediate changes, sustained effects and other skin or clinical outcomes", "role": "Required", "role_reason": "This item distinguishes distinction between intermediate changes, sustained effects and other skin or clinical outcomes to connect the evidence needed for the selected question with the evidence currently available.", "application_exception": "Limited to the stored summary for the selected formulation, population, endpoint and period. It does not substitute for numbers from other formulations/trials/endpoints or unread external material.", "criterion": "Relevant source data and analysis details for distinction between intermediate changes, sustained effects and other skin or clinical outcomes must be provided, with unverified points identified. Preserved wording is linked here; review of the existing content is incomplete.", "basis": "M03 §3.2.1–3.2.4; dose, duration and effect-modification details are internally designed; M03 §3.2.4; internally defined extension boundaries; M04 §4.6.3, M15 §15.3.1–15.3.3; status separation is internally designed", "condition_origin": "Production conditions for turning the preserved account into a table; existing content review remains incomplete, and this is not a record of running an official tool or completing content review", "proposed_research": "A preserved proposal for follow-up research that distinguishes persistence from applicability across formulations and populations. No new investigation, calculation or trial was performed." }, { "item_id": "N28", "question_type": "Harm-information gaps supplementing the efficacy table", "question": "Original safety record and scope", "needed": "12-week safety collection, denominators and frequencies, and rare or long-term harms", "role": "Supplementary", "role_reason": "This item distinguishes 12-week safety collection, denominators and frequencies, and rare or long-term harms to connect the evidence needed for the selected question with the evidence currently available.", "application_exception": "Complements safety-data gaps for the selected subclaim. Intermediate/final skin hydration, self-reported sleepiness or parent cautionary wording are not used to judge safety or create harm-incidence estimates/new use instructions.", "criterion": "Relevant source data and analysis details for 12-week safety collection, denominators and frequencies, and rare or long-term harms must be provided, with unverified points identified. Preserved wording is linked here; review of the existing content is incomplete.", "basis": "M19 §19.1.2–19.2.4; detailed distinctions are Chamgap’s own design; M19 §19.1.2–19.2.4; Chamgap application; M19 §19.1.2–19.2.4; Chamgap application; M19 §19.1.2–19.2.4; Chamgap application", "condition_origin": "Production conditions for turning the preserved account into a table; existing content review remains incomplete, and this is not a record of running an official tool or completing content review", "proposed_research": "A preserved proposal for follow-up research that specifies harm collection and the scope of longer-term or other-population evidence. No new investigation, calculation or trial was performed." }, { "item_id": "N29", "question_type": "Evidence condition", "question": "Parent/subclaim, bilingual text and history", "needed": "Separate preservation of original values, axes, reference date and correction or verification statements", "role": "Required", "role_reason": "This item distinguishes separate preservation of original values, axes, reference date and correction or verification statements to connect the evidence needed for the selected question with the evidence currently available.", "application_exception": "Limited to the stored summary for the selected formulation, population, endpoint and period. It does not substitute for numbers from other formulations/trials/endpoints or unread external material.", "criterion": "Relevant source data and analysis details for separate preservation of original values, axes, reference date and correction or verification statements must be provided, with unverified points identified. Preserved wording is linked here; review of the existing content is incomplete.", "basis": "M04 §4.5, §4.6.3; limits of this material conversion follow the review scope and internal design; M03 §3.1, §3.2.1–3.2.4 question-clarification principles; detailed separation rules are internally designed", "condition_origin": "Production conditions for turning the preserved account into a table; existing content review remains incomplete, and this is not a record of running an official tool or completing content review", "proposed_research": "A preserved proposal for follow-up research that distinguishes original values and history from application of new updates. No new investigation, calculation or trial was performed." }, { "item_id": "N30", "question_type": "Evidence condition", "question": "Summary reading, external materials and links", "needed": "Actual reading scope and access status of original articles, registration, plans and support records", "role": "Required", "role_reason": "This item distinguishes actual reading scope and access status of original articles, registration, plans and support records to connect the evidence needed for the selected question with the evidence currently available.", "application_exception": "Limited to the stored summary for the selected formulation, population, endpoint and period. It does not substitute for numbers from other formulations/trials/endpoints or unread external material.", "criterion": "Relevant source data and analysis details for actual reading scope and access status of original articles, registration, plans and support records must be provided, with unverified points identified. Preserved wording is linked here; review of the existing content is incomplete.", "basis": "M04 §4.5–4.6 material collection/selection principles; acquisition/reading separation and hyperlink specifications are internally designed; M04 §4.5, §4.6.3; limits of this material conversion follow the review scope and internal design", "condition_origin": "Production conditions for turning the preserved account into a table; existing content review remains incomplete, and this is not a record of running an official tool or completing content review", "proposed_research": "A preserved proposal for follow-up research that distinguishes the timing and scope of acquired material when updating. No new investigation, calculation or trial was performed." } ] }