{
  "schema_version": "chamgap-public-criteria-1.0",
  "title": "Winter cod liver oil × Reduced other acute respiratory infections",
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  "translation_date": "2026-10-14",
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  "criteria_date": "2026-10-06",
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    {
      "id": "M03",
      "version": "Cochrane Handbook 6.5 (2024), chapter updated 2023-08",
      "url": "https://www.cochrane.org/authors/handbooks-and-manuals/handbook/current/chapter-03",
      "section": "§3.1, §3.2.1–3.2.3, MECIR C5/C7/C13",
      "official_principle": "Clearly record the question, eligibility conditions and reasons for changes, and distinguish variations in interventions.",
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    {
      "id": "M04",
      "version": "Cochrane Handbook 6.5.1 (2025), chapter updated 2025-03",
      "url": "https://www.cochrane.org/authors/handbooks-and-manuals/handbook/current/chapter-04",
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      "official_principle": "Distinguish studies from reports and link them; do not omit a study solely because results are unreported.",
      "review_level": "Preserved method HTML copies; no current method-content re-review or official tool execution"
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    {
      "id": "M08",
      "version": "Cochrane Handbook 6.5 (2024), chapter updated 2019-10",
      "url": "https://www.cochrane.org/authors/handbooks-and-manuals/handbook/current/chapter-08",
      "section": "§8.1–8.2.3, Table 8.2.a",
      "official_principle": "Define the outcome and effect of interest, then examine randomization, deviations, missing data, measurement and selective reporting.",
      "review_level": "Preserved method HTML copies; no current method-content re-review or official tool execution"
    },
    {
      "id": "M15",
      "version": "Cochrane Handbook 6.5 (2024), chapter updated 2023-08",
      "url": "https://www.cochrane.org/authors/handbooks-and-manuals/handbook/current/chapter-15",
      "section": "§15.2.4, §15.3.1–15.3.3",
      "official_principle": "Distinguish effect estimates, intervals, importance and applicability. Sample size alone does not determine precision.",
      "review_level": "Preserved method HTML copies; no current method-content re-review or official tool execution"
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    {
      "id": "M19",
      "version": "Cochrane Handbook 6.5 (2024), chapter updated 2019-10",
      "url": "https://www.cochrane.org/authors/handbooks-and-manuals/handbook/current/chapter-19",
      "section": "§19.1.2, §19.2.1–19.2.4",
      "official_principle": "Harm questions may require different designs, populations and follow-up from efficacy questions. Case reports do not establish incidence rates.",
      "review_level": "Preserved method HTML copies; no current method-content re-review or official tool execution"
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  "status_dictionary": {
    "Met": "Status for necessary evidence confirmed after existing content review. No completion is declared in the current presentation.",
    "Partly verified": "Some information in the stored summary is linked into the table. External comparison/content review is not complete.",
    "Unverified": "The article leaves this unverified, or required material is absent from the current stored summary. This is distinct from zero, absence or safety.",
    "Review incomplete": "Existing content review remains incomplete.",
    "Not reported": "Not reported within the stored material actually read; not extended to the entire primary paper.",
    "Inaccessible": "Means an actual access failure. Access not attempted here is not assigned this state.",
    "Not applicable": "Not used as a substitute for an evidence gap.",
    "Conflicting data": "Requires an observed disagreement under the same comparison criteria; not automatically judged in this production.",
    "Insufficient evidence for the conditions": "Marks a gap in additional material required by the selected conditions; not a new efficacy grade."
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      "question_type": "Evidence condition",
      "question": "Selected ARI question and original grade",
      "needed": "Existing question/grade/note versus the parent coprimary verdict",
      "role": "Required",
      "role_reason": "An application item distinguishing Existing question/grade/note versus the parent coprimary verdict to connect materials needed for the selected question with available materials.",
      "application_exception": "Limited to the stored summary for the selected formulation, population, endpoint and period. It does not substitute for numbers from other formulations/trials/endpoints or unread external material.",
      "criterion": "Relevant originals and analysis scope for Existing question/grade/note versus the parent coprimary verdict should be available, with unverified items distinguished. Preserved wording is linked here; existing content review remains incomplete.",
      "basis": "M03 §3.1, §3.2.1–3.2.4 question-clarification principles; detailed separation rules are custom design; M03 §3.2.4, M15 §15.3.1–15.3.3; question-specific outcome adaptation is custom design; M04 §4.5, §4.6.3; limits on current material conversion reflect the review scope and custom design",
      "condition_origin": "Production conditions for turning the preserved account into a table; existing content review remains incomplete, and this is not a record of running an official tool or completing content review",
      "proposed_research": "Proposed follow-up comparative research specifying the ARI question/indicators; no new investigation, calculation or trial was performed in this production."
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      "item_id": "N02",
      "question_type": "Evidence condition",
      "question": "Norwegian adults and routine supplementation",
      "needed": "Actual population, eligibility, routine vitamin D exposure and season",
      "role": "Required",
      "role_reason": "An application item distinguishing Actual population, eligibility, routine vitamin D exposure and season to connect materials needed for the selected question with available materials.",
      "application_exception": "Limited to the stored summary for the selected formulation, population, endpoint and period. It does not substitute for numbers from other formulations/trials/endpoints or unread external material.",
      "criterion": "Relevant originals and analysis scope for Actual population, eligibility, routine vitamin D exposure and season should be available, with unverified items distinguished. Preserved wording is linked here; existing content review remains incomplete.",
      "basis": "M03 §3.2.1; Detailed population conditions are Chamgap design; M03 §3.2.1–3.2.4; Dose, duration and effect-modifier details are Chamgap design",
      "condition_origin": "Production conditions for turning the preserved account into a table; existing content review remains incomplete, and this is not a record of running an official tool or completing content review",
      "proposed_research": "Proposed follow-up research specifying population and prior exposure; no new investigation, calculation or trial was performed in this production."
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    {
      "item_id": "N03",
      "question_type": "Evidence condition",
      "question": "Baseline vitamin D status and treatment scope",
      "needed": "Supplement habits versus deficiency diagnosis/baseline status",
      "role": "Required",
      "role_reason": "An application item distinguishing Supplement habits versus deficiency diagnosis/baseline status to connect materials needed for the selected question with available materials.",
      "application_exception": "Limited to the stored summary for the selected formulation, population, endpoint and period. It does not substitute for numbers from other formulations/trials/endpoints or unread external material.",
      "criterion": "Relevant originals and analysis scope for Supplement habits versus deficiency diagnosis/baseline status should be available, with unverified items distinguished. Preserved wording is linked here; existing content review remains incomplete.",
      "basis": "M03 §3.2.1; Detailed population criteria are designed by CHAMGAP; M03 §3.2.1–3.2.4; Dose, duration and effect-modification details are designed by CHAMGAP; M03 §3.2.2–3.2.3; Reverse labels and test adaptations are designed by CHAMGAP",
      "condition_origin": "Production conditions for turning the preserved account into a table; existing content review remains incomplete, and this is not a record of running an official tool or completing content review",
      "proposed_research": "Proposed research separating baseline status from the selected combination-product scope; no new investigation, calculation or trial was performed in this production."
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    {
      "item_id": "N04",
      "question_type": "Evidence condition",
      "question": "Combination-study product identity",
      "needed": "Cod-liver-oil product/combination ingredients versus single-ingredient attribution",
      "role": "Required",
      "role_reason": "An application item distinguishing Cod-liver-oil product/combination ingredients versus single-ingredient attribution to connect materials needed for the selected question with available materials.",
      "application_exception": "Limited to the stored summary for the selected formulation, population, endpoint and period. It does not substitute for numbers from other formulations/trials/endpoints or unread external material.",
      "criterion": "Relevant originals and analysis scope for Cod-liver-oil product/combination ingredients versus single-ingredient attribution should be available, with unverified items distinguished. Preserved wording is linked here; existing content review remains incomplete.",
      "basis": "M03 §3.2.2–3.2.3; Reverse-direction labels and assessment adaptation are Chamgap design; M03 §3.2.3 and M08 §8.2.2–8.2.3; Chamgap application",
      "condition_origin": "Production conditions for turning the preserved account into a table; existing content review remains incomplete, and this is not a record of running an official tool or completing content review",
      "proposed_research": "Proposed follow-up research separating the same combination product from ingredient attribution; no new investigation, calculation or trial was performed in this production."
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    {
      "item_id": "N05",
      "question_type": "Evidence condition",
      "question": "Flavour-matched corn-oil placebo",
      "needed": "Actual placebo, ingredients/sensory features and contact comparison",
      "role": "Required",
      "role_reason": "An application item distinguishing Actual placebo, ingredients/sensory features and contact comparison to connect materials needed for the selected question with available materials.",
      "application_exception": "Limited to the stored summary for the selected formulation, population, endpoint and period. It does not substitute for numbers from other formulations/trials/endpoints or unread external material.",
      "criterion": "Relevant originals and analysis scope for Actual placebo, ingredients/sensory features and contact comparison should be available, with unverified items distinguished. Preserved wording is linked here; existing content review remains incomplete.",
      "basis": "M03 §3.2.2–3.2.3; reverse-direction labels and testing adaptations are internally designed; M08 Table 8.2.a, M03 §3.2.4; internal application",
      "condition_origin": "Production conditions for turning the preserved account into a table; existing content review remains incomplete, and this is not a record of running an official tool or completing content review",
      "proposed_research": "Proposed follow-up trial disclosing actual comparison conditions; no new investigation, calculation or trial was performed in this production."
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    {
      "item_id": "N06",
      "question_type": "Evidence condition",
      "question": "Winter and a median 164 days",
      "needed": "Duration/median versus individual exposure/observation windows",
      "role": "Required",
      "role_reason": "An application item distinguishing Duration/median versus individual exposure/observation windows to connect materials needed for the selected question with available materials.",
      "application_exception": "Limited to the stored summary for the selected formulation, population, endpoint and period. It does not substitute for numbers from other formulations/trials/endpoints or unread external material.",
      "criterion": "Relevant originals and analysis scope for Duration/median versus individual exposure/observation windows should be available, with unverified items distinguished. Preserved wording is linked here; existing content review remains incomplete.",
      "basis": "M03 §3.2.4 and M15 §§15.3.1–15.3.3; question-specific outcome adaptation is Chamgap-designed; M03 §3.2.3 and M08 §§8.2.2–8.2.3; Chamgap adaptation; M03 §§3.2.1–3.2.4; dose, durability and effect-modification details are Chamgap-designed",
      "condition_origin": "Production conditions for turning the preserved account into a table; existing content review remains incomplete, and this is not a record of running an official tool or completing content review",
      "proposed_research": "Proposed follow-up research separating planned/actual duration and season; no new investigation, calculation or trial was performed in this production."
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    {
      "item_id": "N07",
      "question_type": "Evidence condition",
      "question": "Independent allocation department and concealment",
      "needed": "Historical randomization procedures versus actual original-text access",
      "role": "Required",
      "role_reason": "An application item distinguishing Historical randomization procedures versus actual original-text access to connect materials needed for the selected question with available materials.",
      "application_exception": "Limited to the stored summary for the selected formulation, population, endpoint and period. It does not substitute for numbers from other formulations/trials/endpoints or unread external material.",
      "criterion": "Relevant originals and analysis scope for Historical randomization procedures versus actual original-text access should be available, with unverified items distinguished. Preserved wording is linked here; existing content review remains incomplete.",
      "basis": "M08 §8.1–8.2.3; internal application; M04 §4.5–4.6 collection/selection principles; access/reading separation and hyperlink specifications are internally designed",
      "condition_origin": "Production conditions for turning the preserved account into a table; existing content review remains incomplete, and this is not a record of running an official tool or completing content review",
      "proposed_research": "Proposed follow-up trial disclosing allocation procedures; no new investigation, calculation or trial was performed in this production."
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    {
      "item_id": "N08",
      "question_type": "Evidence condition",
      "question": "Quadruple masking and each role",
      "needed": "Masking of participants, researchers/care and data/assessment/analysis personnel",
      "role": "Required",
      "role_reason": "An application item distinguishing Masking of participants, researchers/care and data/assessment/analysis personnel to connect materials needed for the selected question with available materials.",
      "application_exception": "Limited to the stored summary for the selected formulation, population, endpoint and period. It does not substitute for numbers from other formulations/trials/endpoints or unread external material.",
      "criterion": "Relevant originals and analysis scope for Masking of participants, researchers/care and data/assessment/analysis personnel should be available, with unverified items distinguished. Preserved wording is linked here; existing content review remains incomplete.",
      "basis": "M08 Table 8.2.a, M03 §3.2.4; CHAMGAP adaptation; Material collection/selection principles in M04 §4.5–4.6; Separating access from reading and defining hyperlink behavior are designed by CHAMGAP",
      "condition_origin": "Production conditions for turning the preserved account into a table; existing content review remains incomplete, and this is not a record of running an official tool or completing content review",
      "proposed_research": "Proposed follow-up research specifying masking and self-reported measurement; no new investigation, calculation or trial was performed in this production."
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    {
      "item_id": "N09",
      "question_type": "Evidence condition",
      "question": "Self-reported ARI definition",
      "needed": "Self-report, symptoms, diagnostic confirmation and first/repeated infections",
      "role": "Required",
      "role_reason": "An application item distinguishing Self-report, symptoms, diagnostic confirmation and first/repeated infections to connect materials needed for the selected question with available materials.",
      "application_exception": "Limited to the stored summary for the selected formulation, population, endpoint and period. It does not substitute for numbers from other formulations/trials/endpoints or unread external material.",
      "criterion": "Relevant originals and analysis scope for Self-report, symptoms, diagnostic confirmation and first/repeated infections should be available, with unverified items distinguished. Preserved wording is linked here; existing content review remains incomplete.",
      "basis": "M03 §3.2.4, M15 §15.3.1–15.3.3; question-specific outcome adaptations are internally designed; M08 Table 8.2.a, M03 §3.2.4; internal application; M08 §8.2.2, M15 §15.3.1; internal application",
      "condition_origin": "Production conditions for turning the preserved account into a table; existing content review remains incomplete, and this is not a record of running an official tool or completing content review",
      "proposed_research": "Proposed follow-up research separating self-reports from confirmed infections; no new investigation, calculation or trial was performed in this production."
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    {
      "item_id": "N10",
      "question_type": "Evidence condition",
      "question": "Self-reported ARI counts and RR",
      "needed": "Original counts/effects/CI and exact units/denominators",
      "role": "Required",
      "role_reason": "An application item distinguishing Original counts/effects/CI and exact units/denominators to connect materials needed for the selected question with available materials.",
      "application_exception": "Limited to the stored summary for the selected formulation, population, endpoint and period. It does not substitute for numbers from other formulations/trials/endpoints or unread external material.",
      "criterion": "Relevant originals and analysis scope for Original counts/effects/CI and exact units/denominators should be available, with unverified items distinguished. Preserved wording is linked here; existing content review remains incomplete.",
      "basis": "M08 Table 8.2.a, M15 §15.3, M19 §19.1.2–19.2.4; design-specific adaptations are internally designed; M15 §15.3.1–15.3.3; internal application; M08 §8.2.2, M15 §15.3.1; internal application",
      "condition_origin": "Production conditions for turning the preserved account into a table; existing content review remains incomplete, and this is not a record of running an official tool or completing content review",
      "proposed_research": "Proposed research disclosing units/denominators together with effects; no new investigation, calculation or trial was performed in this production."
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    {
      "item_id": "N11",
      "question_type": "Evidence condition",
      "question": "Negative SARS-CoV-2 test indicator",
      "needed": "Negative tests versus ARI/other-pathogen confirmation",
      "role": "Required",
      "role_reason": "An application item distinguishing Negative tests versus ARI/other-pathogen confirmation to connect materials needed for the selected question with available materials.",
      "application_exception": "Limited to the stored summary for the selected formulation, population, endpoint and period. It does not substitute for numbers from other formulations/trials/endpoints or unread external material.",
      "criterion": "Relevant originals and analysis scope for Negative tests versus ARI/other-pathogen confirmation should be available, with unverified items distinguished. Preserved wording is linked here; existing content review remains incomplete.",
      "basis": "M03 §3.2.4, M15 §15.3.1–15.3.3; question-specific outcome adaptations are internally designed; M08 Table 8.2.a, M03 §3.2.4; internal application; M08 §8.2.2, M15 §15.3.1; internal application",
      "condition_origin": "Production conditions for turning the preserved account into a table; existing content review remains incomplete, and this is not a record of running an official tool or completing content review",
      "proposed_research": "Proposed follow-up research separating negative tests from actual ARI confirmation; no new investigation, calculation or trial was performed in this production."
    },
    {
      "item_id": "N12",
      "question_type": "Evidence condition",
      "question": "Testing selection and confirmed-ARI gaps",
      "needed": "Self-report/testing and confirmed/unconfirmed infection scope",
      "role": "Required",
      "role_reason": "An application item distinguishing Self-report/testing and confirmed/unconfirmed infection scope to connect materials needed for the selected question with available materials.",
      "application_exception": "Limited to the stored summary for the selected formulation, population, endpoint and period. It does not substitute for numbers from other formulations/trials/endpoints or unread external material.",
      "criterion": "Relevant originals and analysis scope for Self-report/testing and confirmed/unconfirmed infection scope should be available, with unverified items distinguished. Preserved wording is linked here; existing content review remains incomplete.",
      "basis": "M08 Table 8.2.a, M03 §3.2.4; own application; M03 §3.2.4, M15 §15.3.1–15.3.3; question-specific outcome adaptation is independently designed; M08 Table 8.2.a, M15 §15.3, M19 §19.1.2–19.2.4; design-specific adaptation is independently designed",
      "condition_origin": "Production conditions for turning the preserved account into a table; existing content review remains incomplete, and this is not a record of running an official tool or completing content review",
      "proposed_research": "Proposed research separating self-report/testing selection from confirmed results; no new investigation, calculation or trial was performed in this production."
    },
    {
      "item_id": "N13",
      "question_type": "Evidence condition",
      "question": "PCR COVID-19 is a related outcome",
      "needed": "PCR-confirmed COVID-19 versus other ARI endpoints",
      "role": "Required",
      "role_reason": "An application item distinguishing PCR-confirmed COVID-19 versus other ARI endpoints to connect materials needed for the selected question with available materials.",
      "application_exception": "Limited to the stored summary for the selected formulation, population, endpoint and period. It does not substitute for numbers from other formulations/trials/endpoints or unread external material.",
      "criterion": "Relevant originals and analysis scope for PCR-confirmed COVID-19 versus other ARI endpoints should be available, with unverified items distinguished. Preserved wording is linked here; existing content review remains incomplete.",
      "basis": "M03 §3.2.4, M15 §15.3.1–15.3.3; question-specific outcome adaptations are internally designed; M04 §4.6.1–4.6.2 distinguishes studies from reports; cohort/outcome links are an internal application; M15 §15.3.1–15.3.3; internal application",
      "condition_origin": "Production conditions for turning the preserved account into a table; existing content review remains incomplete, and this is not a record of running an official tool or completing content review",
      "proposed_research": "Proposed follow-up research reporting related endpoints separately; no new investigation, calculation or trial was performed in this production."
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      "question_type": "Evidence condition",
      "question": "Serious COVID-19 is a related outcome",
      "needed": "Serious-outcome definitions/events/ratios versus other ARI",
      "role": "Required",
      "role_reason": "An application item distinguishing Serious-outcome definitions/events/ratios versus other ARI to connect materials needed for the selected question with available materials.",
      "application_exception": "Limited to the stored summary for the selected formulation, population, endpoint and period. It does not substitute for numbers from other formulations/trials/endpoints or unread external material.",
      "criterion": "Relevant originals and analysis scope for Serious-outcome definitions/events/ratios versus other ARI should be available, with unverified items distinguished. Preserved wording is linked here; existing content review remains incomplete.",
      "basis": "M03 §3.2.4, M15 §15.3.1–15.3.3; question-specific outcome adaptations are internally designed; M04 §4.6.1–4.6.2 distinguishes studies from reports; cohort/outcome links are an internal application; M15 §15.3.1–15.3.3; internal application",
      "condition_origin": "Production conditions for turning the preserved account into a table; existing content review remains incomplete, and this is not a record of running an official tool or completing content review",
      "proposed_research": "Proposed follow-up research separating endpoint components/overlap; no new investigation, calculation or trial was performed in this production."
    },
    {
      "item_id": "N15",
      "question_type": "Evidence condition",
      "question": "Four coprimary outcomes and fallback",
      "needed": "Coprimary outcomes/multiplicity, adjusted CI and prespecified hierarchy",
      "role": "Required",
      "role_reason": "An application item distinguishing Coprimary outcomes/multiplicity, adjusted CI and prespecified hierarchy to connect materials needed for the selected question with available materials.",
      "application_exception": "Limited to the stored summary for the selected formulation, population, endpoint and period. It does not substitute for numbers from other formulations/trials/endpoints or unread external material.",
      "criterion": "Relevant originals and analysis scope for Coprimary outcomes/multiplicity, adjusted CI and prespecified hierarchy should be available, with unverified items distinguished. Preserved wording is linked here; existing content review remains incomplete.",
      "basis": "M08 Table 8.2.a, M04 §4.6.3; internal application; M04 §4.6.3, M15 §15.3.1–15.3.3; status separation is internally designed; M04 §4.6.1–4.6.2 distinguishes studies from reports; cohort/outcome links are an internal application",
      "condition_origin": "Production conditions for turning the preserved account into a table; existing content review remains incomplete, and this is not a record of running an official tool or completing content review",
      "proposed_research": "Proposed follow-up research specifying coprimary outcomes and adjusted results; no new investigation, calculation or trial was performed in this production."
    },
    {
      "item_id": "N16",
      "question_type": "Evidence condition",
      "question": "34,601·17,278/17,323",
      "needed": "Randomized population versus indicator-specific observations/denominators",
      "role": "Required",
      "role_reason": "An application item distinguishing Randomized population versus indicator-specific observations/denominators to connect materials needed for the selected question with available materials.",
      "application_exception": "Limited to the stored summary for the selected formulation, population, endpoint and period. It does not substitute for numbers from other formulations/trials/endpoints or unread external material.",
      "criterion": "Relevant originals and analysis scope for Randomized population versus indicator-specific observations/denominators should be available, with unverified items distinguished. Preserved wording is linked here; existing content review remains incomplete.",
      "basis": "M08 Table 8.2.a, M15 §15.3 and M19 §19.1.2–19.2.4; Design-specific adaptation is Chamgap design; M08 §8.2.2 and M15 §15.3.1; Chamgap application",
      "condition_origin": "Production conditions for turning the preserved account into a table; existing content review remains incomplete, and this is not a record of running an official tool or completing content review",
      "proposed_research": "Proposed follow-up research distinguishing recruitment/observation/analysis denominators; no new investigation, calculation or trial was performed in this production."
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    {
      "item_id": "N17",
      "question_type": "Evidence condition",
      "question": "ITT and 0.05% key-variable missingness",
      "needed": "Analysis by assignment and variable-specific missingness/handling scope",
      "role": "Required",
      "role_reason": "An application item distinguishing Analysis by assignment and variable-specific missingness/handling scope to connect materials needed for the selected question with available materials.",
      "application_exception": "Limited to the stored summary for the selected formulation, population, endpoint and period. It does not substitute for numbers from other formulations/trials/endpoints or unread external material.",
      "criterion": "Relevant originals and analysis scope for Analysis by assignment and variable-specific missingness/handling scope should be available, with unverified items distinguished. Preserved wording is linked here; existing content review remains incomplete.",
      "basis": "M08 Table 8.2.a, M15 §15.3, M19 §19.1.2–19.2.4; design-specific adaptations are internally designed; M08 §8.2.2, M15 §15.3.1; internal application; M04 §4.5–4.6 collection/selection principles; access/reading separation and hyperlink specifications are internally designed",
      "condition_origin": "Production conditions for turning the preserved account into a table; existing content review remains incomplete, and this is not a record of running an official tool or completing content review",
      "proposed_research": "Proposed research reporting differences between variable-specific observation and ITT estimation; no new investigation, calculation or trial was performed in this production."
    },
    {
      "item_id": "N18",
      "question_type": "Evidence condition",
      "question": "People, symptom days, repetitions and tests",
      "needed": "Outcome units and repetition/time overlap handling",
      "role": "Required",
      "role_reason": "An application item distinguishing Outcome units and repetition/time overlap handling to connect materials needed for the selected question with available materials.",
      "application_exception": "Limited to the stored summary for the selected formulation, population, endpoint and period. It does not substitute for numbers from other formulations/trials/endpoints or unread external material.",
      "criterion": "Relevant originals and analysis scope for Outcome units and repetition/time overlap handling should be available, with unverified items distinguished. Preserved wording is linked here; existing content review remains incomplete.",
      "basis": "M04 §4.6.1–4.6.2 distinguishes studies from reports; cohort/outcome links are an internal application; M03 §3.2.4, M15 §15.3.1–15.3.3; question-specific outcome adaptations are internally designed; M08 Table 8.2.a, M15 §15.3, M19 §19.1.2–19.2.4; design-specific adaptations are internally designed",
      "condition_origin": "Production conditions for turning the preserved account into a table; existing content review remains incomplete, and this is not a record of running an official tool or completing content review",
      "proposed_research": "Proposed research separately reporting people/events/days/test units; no new investigation, calculation or trial was performed in this production."
    },
    {
      "item_id": "N19",
      "question_type": "Evidence condition",
      "question": "Actual intake and concurrent exposures",
      "needed": "Original exposure/duration versus adherence, vitamins and behaviour/testing differences",
      "role": "Required",
      "role_reason": "An application item distinguishing Original exposure/duration versus adherence, vitamins and behaviour/testing differences to connect materials needed for the selected question with available materials.",
      "application_exception": "Limited to the stored summary for the selected formulation, population, endpoint and period. It does not substitute for numbers from other formulations/trials/endpoints or unread external material.",
      "criterion": "Relevant originals and analysis scope for Original exposure/duration versus adherence, vitamins and behaviour/testing differences should be available, with unverified items distinguished. Preserved wording is linked here; existing content review remains incomplete.",
      "basis": "M03 §3.2.3, M08 §8.2.2–8.2.3; own application; M03 §3.2.2–3.2.3; reverse-direction labels and test adaptations are our own design",
      "condition_origin": "Production conditions for turning the preserved account into a table; existing content review remains incomplete, and this is not a record of running an official tool or completing content review",
      "proposed_research": "Proposed follow-up research specifying actual exposure and concurrent conditions; no new investigation, calculation or trial was performed in this production."
    },
    {
      "item_id": "N20",
      "question_type": "Evidence condition",
      "question": "Between-arm RR/CI and the scope of null findings",
      "needed": "Original relative effects/adjusted CI, within/between-arm and zero/equivalence distinctions",
      "role": "Required",
      "role_reason": "An application item distinguishing Original relative effects/adjusted CI, within/between-arm and zero/equivalence distinctions to connect materials needed for the selected question with available materials.",
      "application_exception": "Limited to the stored summary for the selected formulation, population, endpoint and period. It does not substitute for numbers from other formulations/trials/endpoints or unread external material.",
      "criterion": "Relevant originals and analysis scope for Original relative effects/adjusted CI, within/between-arm and zero/equivalence distinctions should be available, with unverified items distinguished. Preserved wording is linked here; existing content review remains incomplete.",
      "basis": "M08 §8.2.2, M15 §15.3.1; internal application; M15 §15.3.1–15.3.3; internal application; M04 §4.6.3, M15 §15.3.1–15.3.3; status separation is internally designed",
      "condition_origin": "Production conditions for turning the preserved account into a table; existing content review remains incomplete, and this is not a record of running an official tool or completing content review",
      "proposed_research": "Proposed follow-up research reporting effects/precision and applicability; no new investigation, calculation or trial was performed in this production."
    },
    {
      "item_id": "N21",
      "question_type": "Evidence condition",
      "question": "NCT, prespecified dates and original plans",
      "needed": "Registration identifier/dates and preserved prespecified coprimary scope",
      "role": "Required",
      "role_reason": "An application item distinguishing Registration identifier/dates and preserved prespecified coprimary scope to connect materials needed for the selected question with available materials.",
      "application_exception": "Limited to the stored summary for the selected formulation, population, endpoint and period. It does not substitute for numbers from other formulations/trials/endpoints or unread external material.",
      "criterion": "Relevant originals and analysis scope for Registration identifier/dates and preserved prespecified coprimary scope should be available, with unverified items distinguished. Preserved wording is linked here; existing content review remains incomplete.",
      "basis": "M08 Table 8.2.a, M04 §4.6.3; custom application; M04 §4.5–4.6 material-collection/selection principles; separation of access/reading and hyperlink conventions are custom design; M04 §4.5, §4.6.3; limits on current material conversion reflect the review scope and custom design",
      "condition_origin": "Production conditions for turning the preserved account into a table; existing content review remains incomplete, and this is not a record of running an official tool or completing content review",
      "proposed_research": "Proposed research linking and disclosing prespecified coprimary outcomes and actual analysis; no new investigation, calculation or trial was performed in this production."
    },
    {
      "item_id": "N22",
      "question_type": "Evidence condition",
      "question": "Manufacturer funding and products/placebo",
      "needed": "Orkla support items/roles and product identity",
      "role": "Required",
      "role_reason": "An application item distinguishing Orkla support items/roles and product identity to connect materials needed for the selected question with available materials.",
      "application_exception": "Limited to the stored summary for the selected formulation, population, endpoint and period. It does not substitute for numbers from other formulations/trials/endpoints or unread external material.",
      "criterion": "Relevant originals and analysis scope for Orkla support items/roles and product identity should be available, with unverified items distinguished. Preserved wording is linked here; existing content review remains incomplete.",
      "basis": "Chamgap’s own independence/attribution conditions. Official methodological sections used in this pilot do not guarantee every detailed item; M03 §3.2.2–3.2.3; reverse-direction labels and testing adaptations are internally designed",
      "condition_origin": "Production conditions for turning the preserved account into a table; existing content review remains incomplete, and this is not a record of running an official tool or completing content review",
      "proposed_research": "Proposed follow-up trial disclosing support/research roles; no new investigation, calculation or trial was performed in this production."
    },
    {
      "item_id": "N23",
      "question_type": "Evidence condition",
      "question": "University/hospital and other support",
      "needed": "Oslo institutional support and item-specific roles",
      "role": "Required",
      "role_reason": "An application item distinguishing Oslo institutional support and item-specific roles to connect materials needed for the selected question with available materials.",
      "application_exception": "Limited to the stored summary for the selected formulation, population, endpoint and period. It does not substitute for numbers from other formulations/trials/endpoints or unread external material.",
      "criterion": "Relevant originals and analysis scope for Oslo institutional support and item-specific roles should be available, with unverified items distinguished. Preserved wording is linked here; existing content review remains incomplete.",
      "basis": "Chamgap's own conditions for independence and attribution. The official methodological sections used in this example do not validate every detail of these items.",
      "condition_origin": "Production conditions for turning the preserved account into a table; existing content review remains incomplete, and this is not a record of running an official tool or completing content review",
      "proposed_research": "Proposed research separately disclosing support items and roles; no new investigation, calculation or trial was performed in this production."
    },
    {
      "item_id": "N24",
      "question_type": "Evidence condition",
      "question": "Outside relationships and employee authors",
      "needed": "KBH/SMU outside relationships and AS/KTK affiliation scope",
      "role": "Required",
      "role_reason": "An application item distinguishing KBH/SMU outside relationships and AS/KTK affiliation scope to connect materials needed for the selected question with available materials.",
      "application_exception": "Limited to the stored summary for the selected formulation, population, endpoint and period. It does not substitute for numbers from other formulations/trials/endpoints or unread external material.",
      "criterion": "Relevant originals and analysis scope for KBH/SMU outside relationships and AS/KTK affiliation scope should be available, with unverified items distinguished. Preserved wording is linked here; existing content review remains incomplete.",
      "basis": "Chamgap’s own independence/attribution conditions. Official methodological sections used in this pilot do not guarantee every detailed item; M04 §4.5, §4.6.3; current material-conversion limits follow review scope and internal design",
      "condition_origin": "Production conditions for turning the preserved account into a table; existing content review remains incomplete, and this is not a record of running an official tool or completing content review",
      "proposed_research": "Proposed research distinguishing and disclosing relationships inside/outside the study and roles; no new investigation, calculation or trial was performed in this production."
    },
    {
      "item_id": "N25",
      "question_type": "Evidence condition",
      "question": "One trial, four indicators and related sheets",
      "needed": "Report→cohort→indicator/time links and independent replication",
      "role": "Required",
      "role_reason": "An application item distinguishing Report→cohort→indicator/time links and independent replication to connect materials needed for the selected question with available materials.",
      "application_exception": "Limited to the stored summary for the selected formulation, population, endpoint and period. It does not substitute for numbers from other formulations/trials/endpoints or unread external material.",
      "criterion": "Relevant originals and analysis scope for Report→cohort→indicator/time links and independent replication should be available, with unverified items distinguished. Preserved wording is linked here; existing content review remains incomplete.",
      "basis": "Study/report distinction in M04 §4.6.1–4.6.2; Cohort/outcome linkage is Chamgap application; M04 §4.6.1–4.6.2 and M15 §15.3.1; Chamgap application",
      "condition_origin": "Production conditions for turning the preserved account into a table; existing content review remains incomplete, and this is not a record of running an official tool or completing content review",
      "proposed_research": "Proposal for later independent comparative research on the same selected question; no new investigation, calculation or trial was performed in that production."
    },
    {
      "item_id": "N26",
      "question_type": "Evidence condition",
      "question": "Deficiency, high dose, ingredients and long-term scope",
      "needed": "Winter combination product versus other ingredient/treatment/duration applications",
      "role": "Required",
      "role_reason": "An application item distinguishing Winter combination product versus other ingredient/treatment/duration applications to connect materials needed for the selected question with available materials.",
      "application_exception": "Limited to the stored summary for the selected formulation, population, endpoint and period. It does not substitute for numbers from other formulations/trials/endpoints or unread external material.",
      "criterion": "Relevant originals and analysis scope for Winter combination product versus other ingredient/treatment/duration applications should be available, with unverified items distinguished. Preserved wording is linked here; existing content review remains incomplete.",
      "basis": "M03 §3.2.1–3.2.4; dose/duration/effect-modification details are internally designed; M03 §3.2.2–3.2.3; reverse-direction labels and testing adaptations are internally designed; M03 §3.2.4; internal extension boundaries",
      "condition_origin": "Production conditions for turning the preserved account into a table; existing content review remains incomplete, and this is not a record of running an official tool or completing content review",
      "proposed_research": "Proposed research distinguishing combination product from other application specifications; no new investigation, calculation or trial was performed in this production."
    },
    {
      "item_id": "N27",
      "question_type": "Harm-information gaps supplementing the efficacy table",
      "question": "Original safety record and low-grade reporting",
      "needed": "Low-grade side effects, arm-specific frequencies/denominators and long-term harms",
      "role": "Supplementary",
      "role_reason": "An application item distinguishing Low-grade side effects, arm-specific frequencies/denominators and long-term harms to connect materials needed for the selected question with available materials.",
      "application_exception": "Supplements safety-information gaps for the selected subclaim. ARI/test/PCR/serious results or parent safety wording do not yield safety verdicts, harm incidence or new use instructions.",
      "criterion": "Relevant originals and analysis scope for Low-grade side effects, arm-specific frequencies/denominators and long-term harms should be available, with unverified items distinguished. Preserved wording is linked here; existing content review remains incomplete.",
      "basis": "M19 §19.1.2–19.2.4; detailed distinctions are Chamgap’s own design; M19 §19.1.2–19.2.4; Chamgap application; M19 §19.1.2–19.2.4; Chamgap application; M19 §19.1.2–19.2.4; Chamgap application",
      "condition_origin": "Production conditions for turning the preserved account into a table; existing content review remains incomplete, and this is not a record of running an official tool or completing content review",
      "proposed_research": "Proposed research specifying harm collection/scope and follow-up; no new investigation, calculation or trial was performed in this production."
    },
    {
      "item_id": "N28",
      "question_type": "Evidence condition",
      "question": "Original axes, bilingual text, dates and history",
      "needed": "Original parent/subclaim values, axes, corrections and historical verification",
      "role": "Required",
      "role_reason": "An application item distinguishing Original parent/subclaim values, axes, corrections and historical verification to connect materials needed for the selected question with available materials.",
      "application_exception": "Limited to the stored summary for the selected formulation, population, endpoint and period. It does not substitute for numbers from other formulations/trials/endpoints or unread external material.",
      "criterion": "Relevant originals and analysis scope for Original parent/subclaim values, axes, corrections and historical verification should be available, with unverified items distinguished. Preserved wording is linked here; existing content review remains incomplete.",
      "basis": "M04 §4.5, §4.6.3; limits of this material conversion follow the review scope and internal design; M03 §3.1, §3.2.1–3.2.4 question-clarification principles; detailed separation rules are internally designed",
      "condition_origin": "Production conditions for turning the preserved account into a table; existing content review remains incomplete, and this is not a record of running an official tool or completing content review",
      "proposed_research": "Proposed research distinguishing original values/history from new-update scope; no new investigation, calculation or trial was performed in this production."
    },
    {
      "item_id": "N29",
      "question_type": "Evidence condition",
      "question": "Actual summary reading, links and gaps",
      "needed": "Reading preserved summaries versus external text/registration/plan access",
      "role": "Required",
      "role_reason": "An application item distinguishing Reading preserved summaries versus external text/registration/plan access to connect materials needed for the selected question with available materials.",
      "application_exception": "Limited to the stored summary for the selected formulation, population, endpoint and period. It does not substitute for numbers from other formulations/trials/endpoints or unread external material.",
      "criterion": "Relevant originals and analysis scope for Reading preserved summaries versus external text/registration/plan access should be available, with unverified items distinguished. Preserved wording is linked here; existing content review remains incomplete.",
      "basis": "M04 §4.5–4.6 material collection/selection principles; acquisition/reading separation and hyperlink specifications are internally designed; M04 §4.5, §4.6.3; limits of this material conversion follow the review scope and internal design",
      "condition_origin": "Production conditions for turning the preserved account into a table; existing content review remains incomplete, and this is not a record of running an official tool or completing content review",
      "proposed_research": "Proposal for updating while distinguishing actual acquisition/timing/scope; no new investigation, calculation or trial was performed in that production."
    }
  ]
}