{
  "schema_version": "chamgap-public-criteria-1.0",
  "title": "WW 52 versus 12 weeks · Weight loss at 12 months — Evidence Check",
  "language": "en",
  "translation_date": "2026-10-12",
  "criteria_version": "1.0",
  "criteria_date": "2026-10-06",
  "condition_origin": "Chamgap's own application conditions",
  "method_sources": [
    {
      "id": "M03",
      "version": "Cochrane Handbook 6.5 (2024), chapter updated 2023-08",
      "url": "https://www.cochrane.org/authors/handbooks-and-manuals/handbook/current/chapter-03",
      "section": "§3.1, §3.2.1–3.2.3, MECIR C5/C7/C13",
      "official_principle": "Clearly record the question, eligibility conditions and reasons for changes, and distinguish variations in interventions.",
      "review_level": "Link preserved methodological application records; no current clinical-content reassessment or external-link verification was performed."
    },
    {
      "id": "M04",
      "version": "Cochrane Handbook 6.5.1 (2025), chapter updated 2025-03",
      "url": "https://www.cochrane.org/authors/handbooks-and-manuals/handbook/current/chapter-04",
      "section": "§4.5, §4.6.1–4.6.3, MECIR C42",
      "official_principle": "Distinguish studies from reports and link them; do not omit a study solely because results are unreported.",
      "review_level": "Link preserved methodological application records; no current clinical-content reassessment or external-link verification was performed."
    },
    {
      "id": "M08",
      "version": "Cochrane Handbook 6.5 (2024), chapter updated 2019-10",
      "url": "https://www.cochrane.org/authors/handbooks-and-manuals/handbook/current/chapter-08",
      "section": "§8.1–8.2.3, Table 8.2.a",
      "official_principle": "Define the outcome and effect of interest, then examine randomization, deviations, missing data, measurement and selective reporting.",
      "review_level": "Link preserved methodological application records; no current clinical-content reassessment or external-link verification was performed."
    },
    {
      "id": "M15",
      "version": "Cochrane Handbook 6.5 (2024), chapter updated 2023-08",
      "url": "https://www.cochrane.org/authors/handbooks-and-manuals/handbook/current/chapter-15",
      "section": "§15.2.4, §15.3.1–15.3.3",
      "official_principle": "Distinguish effect estimates, intervals, importance and applicability. Sample size alone does not determine precision.",
      "review_level": "Link preserved methodological application records; no current clinical-content reassessment or external-link verification was performed."
    },
    {
      "id": "M19",
      "version": "Cochrane Handbook 6.5 (2024), chapter updated 2019-10",
      "url": "https://www.cochrane.org/authors/handbooks-and-manuals/handbook/current/chapter-19",
      "section": "§19.1.2, §19.2.1–19.2.4",
      "official_principle": "Harm questions may require different designs, populations and follow-up from efficacy questions. Case reports do not establish incidence rates.",
      "review_level": "Link preserved methodological application records; no current clinical-content reassessment or external-link verification was performed."
    }
  ],
  "status_dictionary": {
    "Partly verified": "Some information exists in the preserved review summary; detailed original materials remain unverified. This does not certify a passed review or clinical efficacy.",
    "Unverified": "Detailed materials for the selected condition could not be established within the stored scope; this does not mean zero effect, zero studies or safety",
    "Review incomplete": "Review of existing content incomplete",
    "Met": "Use only within the relevant conditions after existing content review; no automatic designation in this preparation",
    "Not reported": "Distinguish only within materials actually read; do not turn unread external materials into unreported findings",
    "Inaccessible": "Not applied during this preparation because actual access was not tested",
    "Not applicable": "Use with a reason for non-applicability based on an explicit question boundary",
    "Conflicting data": "Judge after actual material comparison; review was not performed during this preparation",
    "Insufficient evidence for the conditions": "Do not use as a clinical grade encompassing currently unread materials"
  },
  "requirements": [
    {
      "item_id": "N01",
      "question_type": "Efficacy comparison · Preserved-material preparation",
      "question": "What are the original selected question and subclaim verdict?",
      "needed": "Original wording, subclaim grade/note and parent context for weight loss at 12 months",
      "role": "Required",
      "role_reason": "Preparation condition clearly showing required evidence, current materials and gaps for the selected question",
      "application_exception": "Retain original values/scope only; other groups, time points, outcomes or formulations do not fill unverified matters.",
      "criterion": "Original wording, subclaim grade/note and parent context for weight loss at 12 months; distinguish direct materials, denominators, scope and unverified matters without new effects, verdicts or independence certification.",
      "basis": "Existing application conditions and preserved methodological links are retained for preparation; this does not indicate completed review of the whole definition.",
      "condition_origin": "Newly written preparation conditions; existing content review remains incomplete, without automatic content-review gate approval",
      "proposed_research": "Record the original verdict, this preparation and existing-content review as separate events."
    },
    {
      "item_id": "N02",
      "question_type": "Efficacy comparison · Preserved-material preparation",
      "question": "Does the selected comparison concern durations of the same WW program?",
      "needed": "Actual interventions and comparison questions for 52 weeks, 12 weeks and brief intervention",
      "role": "Required",
      "role_reason": "Preparation condition clearly showing required evidence, current materials and gaps for the selected question",
      "application_exception": "Retain original values/scope only; other groups, time points, outcomes or formulations do not fill unverified matters.",
      "criterion": "Actual interventions and comparison questions for 52 weeks, 12 weeks and brief intervention; distinguish direct materials, denominators, scope and unverified matters without new effects, verdicts or independence certification.",
      "basis": "Existing application conditions and preserved methodological links are retained for preparation; this does not indicate completed review of the whole definition.",
      "condition_origin": "Newly written preparation conditions; existing content review remains incomplete, without automatic content-review gate approval",
      "proposed_research": "Present duration comparison and comparisons with other controls as separate questions."
    },
    {
      "item_id": "N03",
      "question_type": "Efficacy comparison · Preserved-material preparation",
      "question": "Who was recruited, and what is the applicability?",
      "needed": "Primary-care population eligibility, exclusions and baseline characteristics",
      "role": "Required",
      "role_reason": "Preparation condition clearly showing required evidence, current materials and gaps for the selected question",
      "application_exception": "Retain original values/scope only; other groups, time points, outcomes or formulations do not fill unverified matters.",
      "criterion": "Primary-care population eligibility, exclusions and baseline characteristics; distinguish direct materials, denominators, scope and unverified matters without new effects, verdicts or independence certification.",
      "basis": "Existing application conditions and preserved methodological links are retained for preparation; this does not indicate completed review of the whole definition.",
      "condition_origin": "Newly written preparation conditions; existing content review remains incomplete, without automatic content-review gate approval",
      "proposed_research": "Present the recruited population and applicable question scope."
    },
    {
      "item_id": "N04",
      "question_type": "Efficacy comparison · Preserved-material preparation",
      "question": "What was the research identity of the 52-week intervention?",
      "needed": "Program, meetings, referral and actual participation/exposure specifications",
      "role": "Required",
      "role_reason": "Preparation condition clearly showing required evidence, current materials and gaps for the selected question",
      "application_exception": "Retain original values/scope only; other groups, time points, outcomes or formulations do not fill unverified matters.",
      "criterion": "Program, meetings, referral and actual participation/exposure specifications; distinguish direct materials, denominators, scope and unverified matters without new effects, verdicts or independence certification.",
      "basis": "Existing application conditions and preserved methodological links are retained for preparation; this does not indicate completed review of the whole definition.",
      "condition_origin": "Newly written preparation conditions; existing content review remains incomplete, without automatic content-review gate approval",
      "proposed_research": "Distinguish the intervention’s research identity from actual participation and exposure."
    },
    {
      "item_id": "N05",
      "question_type": "Efficacy comparison · Preserved-material preparation",
      "question": "Are the 12-week active control and brief-intervention group kept separate?",
      "needed": "Contents, denominators and effect of interest for each comparison group",
      "role": "Required",
      "role_reason": "Preparation condition clearly showing required evidence, current materials and gaps for the selected question",
      "application_exception": "Retain original values/scope only; other groups, time points, outcomes or formulations do not fill unverified matters.",
      "criterion": "Contents, denominators and effect of interest for each comparison group; distinguish direct materials, denominators, scope and unverified matters without new effects, verdicts or independence certification.",
      "basis": "Existing application conditions and preserved methodological links are retained for preparation; this does not indicate completed review of the whole definition.",
      "condition_origin": "Newly written preparation conditions; existing content review remains incomplete, without automatic content-review gate approval",
      "proposed_research": "Retain all three groups while displaying the selected two-group effect separately."
    },
    {
      "item_id": "N06",
      "question_type": "Efficacy comparison · Preserved-material preparation",
      "question": "Have allocation, concealment and masking details been read?",
      "needed": "Randomization sequence, concealment and outcome-assessor masking materials",
      "role": "Required",
      "role_reason": "Preparation condition clearly showing required evidence, current materials and gaps for the selected question",
      "application_exception": "Retain original values/scope only; other groups, time points, outcomes or formulations do not fill unverified matters.",
      "criterion": "Randomization sequence, concealment and outcome-assessor masking materials; distinguish direct materials, denominators, scope and unverified matters without new effects, verdicts or independence certification.",
      "basis": "Existing application conditions and preserved methodological links are retained for preparation; this does not indicate completed review of the whole definition.",
      "condition_origin": "Newly written preparation conditions; existing content review remains incomplete, without automatic content-review gate approval",
      "proposed_research": "Distinguish the design label from actual implementation details."
    },
    {
      "item_id": "N07",
      "question_type": "Efficacy comparison · Preserved-material preparation",
      "question": "Are randomized and measured 12-month denominators distinguished?",
      "needed": "Group-specific flow through allocation, follow-up, measurement and analysis",
      "role": "Required",
      "role_reason": "Preparation condition clearly showing required evidence, current materials and gaps for the selected question",
      "application_exception": "Retain original values/scope only; other groups, time points, outcomes or formulations do not fill unverified matters.",
      "criterion": "Group-specific flow through allocation, follow-up, measurement and analysis; distinguish direct materials, denominators, scope and unverified matters without new effects, verdicts or independence certification.",
      "basis": "Existing application conditions and preserved methodological links are retained for preparation; this does not indicate completed review of the whole definition.",
      "condition_origin": "Newly written preparation conditions; existing content review remains incomplete, without automatic content-review gate approval",
      "proposed_research": "Present allocation, measurement and analysis denominators separately."
    },
    {
      "item_id": "N08",
      "question_type": "Efficacy comparison · Preserved-material preparation",
      "question": "Are missing measurements and multiple imputation retained in interpretation?",
      "needed": "Group-specific missingness reasons, imputation models/assumptions and sensitivity analysis",
      "role": "Required",
      "role_reason": "Preparation condition clearly showing required evidence, current materials and gaps for the selected question",
      "application_exception": "Retain original values/scope only; other groups, time points, outcomes or formulations do not fill unverified matters.",
      "criterion": "Group-specific missingness reasons, imputation models/assumptions and sensitivity analysis; distinguish direct materials, denominators, scope and unverified matters without new effects, verdicts or independence certification.",
      "basis": "Existing application conditions and preserved methodological links are retained for preparation; this does not indicate completed review of the whole definition.",
      "condition_origin": "Newly written preparation conditions; existing content review remains incomplete, without automatic content-review gate approval",
      "proposed_research": "Present measured information separately from assumption-based analyses."
    },
    {
      "item_id": "N09",
      "question_type": "Efficacy comparison · Preserved-material preparation",
      "question": "Are actual attendance, co-exposure and between-group changes verified?",
      "needed": "Attendance, program use, accompanying management and group-change materials",
      "role": "Required",
      "role_reason": "Preparation condition clearly showing required evidence, current materials and gaps for the selected question",
      "application_exception": "Retain original values/scope only; other groups, time points, outcomes or formulations do not fill unverified matters.",
      "criterion": "Attendance, program use, accompanying management and group-change materials; distinguish direct materials, denominators, scope and unverified matters without new effects, verdicts or independence certification.",
      "basis": "Existing application conditions and preserved methodological links are retained for preparation; this does not indicate completed review of the whole definition.",
      "condition_origin": "Newly written preparation conditions; existing content review remains incomplete, without automatic content-review gate approval",
      "proposed_research": "Distinguish allocation effects from actual participation and accompanying exposure."
    },
    {
      "item_id": "N10",
      "question_type": "Efficacy comparison · Preserved-material preparation",
      "question": "Are weight measurement and timing specified?",
      "needed": "One-year weight measurement procedure, equipment, units and timing",
      "role": "Required",
      "role_reason": "Preparation condition clearly showing required evidence, current materials and gaps for the selected question",
      "application_exception": "Retain original values/scope only; other groups, time points, outcomes or formulations do not fill unverified matters.",
      "criterion": "One-year weight measurement procedure, equipment, units and timing; distinguish direct materials, denominators, scope and unverified matters without new effects, verdicts or independence certification.",
      "basis": "Existing application conditions and preserved methodological links are retained for preparation; this does not indicate completed review of the whole definition.",
      "condition_origin": "Newly written preparation conditions; existing content review remains incomplete, without automatic content-review gate approval",
      "proposed_research": "Present weight, measurement timing and units together."
    },
    {
      "item_id": "N11",
      "question_type": "Efficacy comparison · Preserved-material preparation",
      "question": "Are within-group changes and adjusted between-group differences separate values?",
      "needed": "Original within-group changes and adjusted between-group estimate",
      "role": "Required",
      "role_reason": "Preparation condition clearly showing required evidence, current materials and gaps for the selected question",
      "application_exception": "Retain original values/scope only; other groups, time points, outcomes or formulations do not fill unverified matters.",
      "criterion": "Original within-group changes and adjusted between-group estimate; distinguish direct materials, denominators, scope and unverified matters without new effects, verdicts or independence certification.",
      "basis": "Existing application conditions and preserved methodological links are retained for preparation; this does not indicate completed review of the whole definition.",
      "condition_origin": "Newly written preparation conditions; existing content review remains incomplete, without automatic content-review gate approval",
      "proposed_research": "Display within-group changes separately alongside the adjusted between-group effect."
    },
    {
      "item_id": "N12",
      "question_type": "Efficacy comparison · Preserved-material preparation",
      "question": "What are the 12-month between-group effect, interval and test?",
      "needed": "Directly reported difference, CI and P value for selected 52 versus 12 weeks",
      "role": "Required",
      "role_reason": "Preparation condition clearly showing required evidence, current materials and gaps for the selected question",
      "application_exception": "Retain original values/scope only; other groups, time points, outcomes or formulations do not fill unverified matters.",
      "criterion": "Directly reported difference, CI and P value for selected 52 versus 12 weeks; distinguish direct materials, denominators, scope and unverified matters without new effects, verdicts or independence certification.",
      "basis": "Existing application conditions and preserved methodological links are retained for preparation; this does not indicate completed review of the whole definition.",
      "condition_origin": "Newly written preparation conditions; existing content review remains incomplete, without automatic content-review gate approval",
      "proposed_research": "Present directly reported values with precision and applicability limits."
    },
    {
      "item_id": "N13",
      "question_type": "Efficacy comparison · Preserved-material preparation",
      "question": "Are the adjustment model and effect of interest known?",
      "needed": "Covariates, analysis population, imputation and model specifications",
      "role": "Required",
      "role_reason": "Preparation condition clearly showing required evidence, current materials and gaps for the selected question",
      "application_exception": "Retain original values/scope only; other groups, time points, outcomes or formulations do not fill unverified matters.",
      "criterion": "Covariates, analysis population, imputation and model specifications; distinguish direct materials, denominators, scope and unverified matters without new effects, verdicts or independence certification.",
      "basis": "Existing application conditions and preserved methodological links are retained for preparation; this does not indicate completed review of the whole definition.",
      "condition_origin": "Newly written preparation conditions; existing content review remains incomplete, without automatic content-review gate approval",
      "proposed_research": "Distinguish allocation, participation and completer effects from imputed estimates."
    },
    {
      "item_id": "N14",
      "question_type": "Efficacy comparison · Preserved-material preparation",
      "question": "Are the preceding and selected hierarchical comparisons distinguished?",
      "needed": "Original testing order, plans and results for preceding and subsequent comparisons",
      "role": "Required",
      "role_reason": "Preparation condition clearly showing required evidence, current materials and gaps for the selected question",
      "application_exception": "Retain original values/scope only; other groups, time points, outcomes or formulations do not fill unverified matters.",
      "criterion": "Original testing order, plans and results for preceding and subsequent comparisons; distinguish direct materials, denominators, scope and unverified matters without new effects, verdicts or independence certification.",
      "basis": "Existing application conditions and preserved methodological links are retained for preparation; this does not indicate completed review of the whole definition.",
      "condition_origin": "Newly written preparation conditions; existing content review remains incomplete, without automatic content-review gate approval",
      "proposed_research": "Link the preceding gatekeeping comparison separately from the selected effect."
    },
    {
      "item_id": "N15",
      "question_type": "Efficacy comparison · Preserved-material preparation",
      "question": "What is the reading scope for registration and plans?",
      "needed": "Registration identifier/timing, protocol, SAP and change history",
      "role": "Required",
      "role_reason": "Preparation condition clearly showing required evidence, current materials and gaps for the selected question",
      "application_exception": "Retain original values/scope only; other groups, time points, outcomes or formulations do not fill unverified matters.",
      "criterion": "Registration identifier/timing, protocol, SAP and change history; distinguish direct materials, denominators, scope and unverified matters without new effects, verdicts or independence certification.",
      "basis": "Existing application conditions and preserved methodological links are retained for preparation; this does not indicate completed review of the whole definition.",
      "condition_origin": "Newly written preparation conditions; existing content review remains incomplete, without automatic content-review gate approval",
      "proposed_research": "Distinguish the original identifier from actual material reading and prespecification."
    },
    {
      "item_id": "N16",
      "question_type": "Efficacy comparison · Preserved-material preparation",
      "question": "Are sample-size assumptions distinguished from minimum clinical importance?",
      "needed": "Sample-size assumptions and declared importance criterion",
      "role": "Required",
      "role_reason": "Preparation condition clearly showing required evidence, current materials and gaps for the selected question",
      "application_exception": "Retain original values/scope only; other groups, time points, outcomes or formulations do not fill unverified matters.",
      "criterion": "Sample-size assumptions and declared importance criterion; distinguish direct materials, denominators, scope and unverified matters without new effects, verdicts or independence certification.",
      "basis": "Existing application conditions and preserved methodological links are retained for preparation; this does not indicate completed review of the whole definition.",
      "condition_origin": "Newly written preparation conditions; existing content review remains incomplete, without automatic content-review gate approval",
      "proposed_research": "Present detection assumptions separately from clinical importance."
    },
    {
      "item_id": "N17",
      "question_type": "Efficacy comparison · Preserved-material preparation",
      "question": "Are 12-month and 24-month effects distinguished?",
      "needed": "Actual comparison, effect, denominator and subsequent exposure by time point",
      "role": "Required",
      "role_reason": "Preparation condition clearly showing required evidence, current materials and gaps for the selected question",
      "application_exception": "Retain original values/scope only; other groups, time points, outcomes or formulations do not fill unverified matters.",
      "criterion": "Actual comparison, effect, denominator and subsequent exposure by time point; distinguish direct materials, denominators, scope and unverified matters without new effects, verdicts or independence certification.",
      "basis": "Existing application conditions and preserved methodological links are retained for preparation; this does not indicate completed review of the whole definition.",
      "condition_origin": "Newly written preparation conditions; existing content review remains incomplete, without automatic content-review gate approval",
      "proposed_research": "Display one-year and 24-month estimates separately."
    },
    {
      "item_id": "N18",
      "question_type": "Efficacy comparison · Preserved-material preparation",
      "question": "Does 12-month superiority establish five-year maintenance?",
      "needed": "Direct five-year comparison and uncertainty in the same trial",
      "role": "Required",
      "role_reason": "Preparation condition clearly showing required evidence, current materials and gaps for the selected question",
      "application_exception": "Retain original values/scope only; other groups, time points, outcomes or formulations do not fill unverified matters.",
      "criterion": "Direct five-year comparison and uncertainty in the same trial; distinguish direct materials, denominators, scope and unverified matters without new effects, verdicts or independence certification.",
      "basis": "Existing application conditions and preserved methodological links are retained for preparation; this does not indicate completed review of the whole definition.",
      "condition_origin": "Newly written preparation conditions; existing content review remains incomplete, without automatic content-review gate approval",
      "proposed_research": "Distinguish short-term superiority from the long-term null result."
    },
    {
      "item_id": "N19",
      "question_type": "Efficacy comparison · Preserved-material preparation",
      "question": "Are five-year measurements and follow-up denominators separate from 12 months?",
      "needed": "Five-year follow-up, measurements, group denominators, missingness and analysis assumptions",
      "role": "Required",
      "role_reason": "Preparation condition clearly showing required evidence, current materials and gaps for the selected question",
      "application_exception": "Retain original values/scope only; other groups, time points, outcomes or formulations do not fill unverified matters.",
      "criterion": "Five-year follow-up, measurements, group denominators, missingness and analysis assumptions; distinguish direct materials, denominators, scope and unverified matters without new effects, verdicts or independence certification.",
      "basis": "Existing application conditions and preserved methodological links are retained for preparation; this does not indicate completed review of the whole definition.",
      "condition_origin": "Newly written preparation conditions; existing content review remains incomplete, without automatic content-review gate approval",
      "proposed_research": "Separate actual observed and analysis denominators by time point."
    },
    {
      "item_id": "N20",
      "question_type": "Efficacy comparison · Preserved-material preparation",
      "question": "Is weight loss being extended to other clinical outcomes?",
      "needed": "Direct outcomes for weight versus clinical events, function and quality of life",
      "role": "Required",
      "role_reason": "Preparation condition clearly showing required evidence, current materials and gaps for the selected question",
      "application_exception": "Retain original values/scope only; other groups, time points, outcomes or formulations do not fill unverified matters.",
      "criterion": "Direct outcomes for weight versus clinical events, function and quality of life; distinguish direct materials, denominators, scope and unverified matters without new effects, verdicts or independence certification.",
      "basis": "Existing application conditions and preserved methodological links are retained for preparation; this does not indicate completed review of the whole definition.",
      "condition_origin": "Newly written preparation conditions; existing content review remains incomplete, without automatic content-review gate approval",
      "proposed_research": "Distinguish weight change from direct evidence for other outcomes."
    },
    {
      "item_id": "N21",
      "question_type": "Efficacy comparison · Preserved-material preparation",
      "question": "Are the main report, five-year follow-up and sibling sheets kept within the same trial?",
      "needed": "WRAP bibliography, registration, participants and follow-up relationships",
      "role": "Required",
      "role_reason": "Preparation condition clearly showing required evidence, current materials and gaps for the selected question",
      "application_exception": "Retain original values/scope only; other groups, time points, outcomes or formulations do not fill unverified matters.",
      "criterion": "WRAP bibliography, registration, participants and follow-up relationships; distinguish direct materials, denominators, scope and unverified matters without new effects, verdicts or independence certification.",
      "basis": "Existing application conditions and preserved methodological links are retained for preparation; this does not indicate completed review of the whole definition.",
      "condition_origin": "Newly written preparation conditions; existing content review remains incomplete, without automatic content-review gate approval",
      "proposed_research": "Distinguish report slots from trial and participant units."
    },
    {
      "item_id": "N22",
      "question_type": "Efficacy comparison · Preserved-material preparation",
      "question": "Are other independent replications and generalization materials available?",
      "needed": "Actual independent reports for the same comparison, population and duration",
      "role": "Required",
      "role_reason": "Preparation condition clearly showing required evidence, current materials and gaps for the selected question",
      "application_exception": "Retain original values/scope only; other groups, time points, outcomes or formulations do not fill unverified matters.",
      "criterion": "Actual independent reports for the same comparison, population and duration; distinguish direct materials, denominators, scope and unverified matters without new effects, verdicts or independence certification.",
      "basis": "Existing application conditions and preserved methodological links are retained for preparation; this does not indicate completed review of the whole definition.",
      "condition_origin": "Newly written preparation conditions; existing content review remains incomplete, without automatic content-review gate approval",
      "proposed_research": "Distinguish follow-up in the same cohort from other independent replication."
    },
    {
      "item_id": "N23",
      "question_type": "Efficacy comparison · Preserved-material preparation",
      "question": "Are consortium funding, industry funding and program access distinguished?",
      "needed": "Research funding, program support, contracts and sponsor-role disclosures",
      "role": "Required",
      "role_reason": "Preparation condition clearly showing required evidence, current materials and gaps for the selected question",
      "application_exception": "Retain original values/scope only; other groups, time points, outcomes or formulations do not fill unverified matters.",
      "criterion": "Research funding, program support, contracts and sponsor-role disclosures; distinguish direct materials, denominators, scope and unverified matters without new effects, verdicts or independence certification.",
      "basis": "Existing application conditions and preserved methodological links are retained for preparation; this does not indicate completed review of the whole definition.",
      "condition_origin": "Newly written preparation conditions; existing content review remains incomplete, without automatic content-review gate approval",
      "proposed_research": "Display public, nonprofit and industry funding separately from program support."
    },
    {
      "item_id": "N24",
      "question_type": "Efficacy comparison · Preserved-material preparation",
      "question": "Are WW funding to authors’ institutions and employee authors distinguished?",
      "needed": "Author-specific affiliations, contributions, institutional support and COI disclosures",
      "role": "Required",
      "role_reason": "Preparation condition clearly showing required evidence, current materials and gaps for the selected question",
      "application_exception": "Retain original values/scope only; other groups, time points, outcomes or formulations do not fill unverified matters.",
      "criterion": "Author-specific affiliations, contributions, institutional support and COI disclosures; distinguish direct materials, denominators, scope and unverified matters without new effects, verdicts or independence certification.",
      "basis": "Existing application conditions and preserved methodological links are retained for preparation; this does not indicate completed review of the whole definition.",
      "condition_origin": "Newly written preparation conditions; existing content review remains incomplete, without automatic content-review gate approval",
      "proposed_research": "Distinguish institutional support from employment, analysis and publication roles."
    },
    {
      "item_id": "N25",
      "question_type": "Efficacy comparison · Preserved-material preparation",
      "question": "Are contracted analysis, medical writing, publication fees and program control known?",
      "needed": "Industry-partner/researcher, analysis, writing and publication role disclosures",
      "role": "Required",
      "role_reason": "Preparation condition clearly showing required evidence, current materials and gaps for the selected question",
      "application_exception": "Retain original values/scope only; other groups, time points, outcomes or formulations do not fill unverified matters.",
      "criterion": "Industry-partner/researcher, analysis, writing and publication role disclosures; distinguish direct materials, denominators, scope and unverified matters without new effects, verdicts or independence certification.",
      "basis": "Existing application conditions and preserved methodological links are retained for preparation; this does not indicate completed review of the whole definition.",
      "condition_origin": "Newly written preparation conditions; existing content review remains incomplete, without automatic content-review gate approval",
      "proposed_research": "Present reported support separately from unverified roles."
    },
    {
      "item_id": "N26",
      "question_type": "Supplementary harm evidence",
      "question": "What is the scope of the intervention-related adverse-event account?",
      "needed": "Event definitions, causal classification, collection and group-specific exposure denominators",
      "role": "Supplementary",
      "role_reason": "Supplementary condition showing harms/safety-material scope separately from efficacy",
      "application_exception": "Retain original values/scope only; other groups, time points, outcomes or formulations do not fill unverified matters.",
      "criterion": "Event definitions, causal classification, collection and group-specific exposure denominators; distinguish direct materials, denominators, scope and unverified matters without new effects, verdicts or independence certification.",
      "basis": "Existing application conditions and preserved methodological links are retained for preparation; this does not indicate completed review of the whole definition.",
      "condition_origin": "Newly written preparation conditions; existing content review remains incomplete, without automatic content-review gate approval",
      "proposed_research": "Distinguish all events from intervention-related events."
    },
    {
      "item_id": "N27",
      "question_type": "Supplementary harm evidence",
      "question": "Is equal safety between the two referral durations established?",
      "needed": "Duration-specific harms comparisons, estimates, intervals and denominators",
      "role": "Supplementary",
      "role_reason": "Supplementary condition showing harms/safety-material scope separately from efficacy",
      "application_exception": "Retain original values/scope only; other groups, time points, outcomes or formulations do not fill unverified matters.",
      "criterion": "Duration-specific harms comparisons, estimates, intervals and denominators; distinguish direct materials, denominators, scope and unverified matters without new effects, verdicts or independence certification.",
      "basis": "Existing application conditions and preserved methodological links are retained for preparation; this does not indicate completed review of the whole definition.",
      "condition_origin": "Newly written preparation conditions; existing content review remains incomplete, without automatic content-review gate approval",
      "proposed_research": "Distinguish efficacy superiority from harms comparisons and equivalence."
    },
    {
      "item_id": "N28",
      "question_type": "Supplementary harm evidence",
      "question": "Are separate long-term and rare-harm materials required?",
      "needed": "Actual long-term follow-up, discontinuation, exposure and rare-event materials",
      "role": "Supplementary",
      "role_reason": "Supplementary condition showing harms/safety-material scope separately from efficacy",
      "application_exception": "Retain original values/scope only; other groups, time points, outcomes or formulations do not fill unverified matters.",
      "criterion": "Actual long-term follow-up, discontinuation, exposure and rare-event materials; distinguish direct materials, denominators, scope and unverified matters without new effects, verdicts or independence certification.",
      "basis": "Existing application conditions and preserved methodological links are retained for preparation; this does not indicate completed review of the whole definition.",
      "condition_origin": "Newly written preparation conditions; existing content review remains incomplete, without automatic content-review gate approval",
      "proposed_research": "Present long-term weight effects separately from long-term safety information."
    },
    {
      "item_id": "N29",
      "question_type": "Efficacy comparison · Preserved-material preparation",
      "question": "Are the read summary and unread external materials distinguished?",
      "needed": "Preserved JSON, bibliography links, abstract, full-text, registration and planning status",
      "role": "Required",
      "role_reason": "Preparation condition clearly showing required evidence, current materials and gaps for the selected question",
      "application_exception": "Retain original values/scope only; other groups, time points, outcomes or formulations do not fill unverified matters.",
      "criterion": "Preserved JSON, bibliography links, abstract, full-text, registration and planning status; distinguish direct materials, denominators, scope and unverified matters without new effects, verdicts or independence certification.",
      "basis": "Existing application conditions and preserved methodological links are retained for preparation; this does not indicate completed review of the whole definition.",
      "condition_origin": "Newly written preparation conditions; existing content review remains incomplete, without automatic content-review gate approval",
      "proposed_research": "Show summary reading separately from material-specific external nonreading"
    },
    {
      "item_id": "N30",
      "question_type": "Efficacy comparison · Preserved-material preparation",
      "question": "Are original verdict/history and candidate states separate from preparation?",
      "needed": "Korean/English, axes, dates, corrections, selected record link and preparation events",
      "role": "Required",
      "role_reason": "Preparation condition clearly showing required evidence, current materials and gaps for the selected question",
      "application_exception": "Retain original values/scope only; other groups, time points, outcomes or formulations do not fill unverified matters.",
      "criterion": "Korean/English, axes, dates, corrections, selected record link and preparation events; distinguish direct materials, denominators, scope and unverified matters without new effects, verdicts or independence certification.",
      "basis": "Existing application conditions and preserved methodological links are retained for preparation; this does not indicate completed review of the whole definition.",
      "condition_origin": "Newly written preparation conditions; existing content review remains incomplete, without automatic content-review gate approval",
      "proposed_research": "Record original history, preparation and existing-content review as separate events."
    }
  ]
}