# Work-focused CBT and job support × Work participation at 12 months — Evidence Check

Verdict 2954 · Evidence Check

Stored-material review date: Not recorded  
Original evidence cut-off: 2026-08-26  
Review-criteria version: 1.0  
Public page/material preparation date: 2026-10-12

Clinical papers were not read directly; existing review summaries were checked. No new clinical-literature search was performed. Unverified does not mean that research is absent or that there is no effect.

## Assessment scope

- Population: 1,193 adults with anxiety/depression randomized at six Norwegian centers (630/563); high suicide risk, severe mental illness and active substance use excluded; exact long-term denominators separately unverified
- Ingredient, formulation and route: Combined AWaC service with up to 15 sessions of work-focused CBT and individual job support
- Dose: Original study-service exposure context, not treatment/job-support implementation instructions; actual participation and subsequent exposure details unverified
- Comparator: Usual care; details of concomitant/additional treatments and arm-specific changes unread
- Measured outcome: Original wording: maintained or restored work participation at 12 months; distinguish maintained/increased wording, baseline classifications and component outcomes
- Duration: Distinguish the 12-month primary outcome, 18-month observation and 10~46-month long-term results
- Questions outside this scope: No new evidence, effects, CIs, calculations, verdicts, independence certification, participant totals, psychological treatment/job-support/drug changes or treatment instructions are created

## Checklist items

### N01 · What are the selected 12-month question and original subclaim verdict?

Verification status: Partly verified  
Reading scope: Summary read; related external material unread

- Current findings: The selected stored wording is maintained or restored work participation at 12 months, original grade B, with the note register-based adjusted difference +6.2 percentage points. The parent is B with 76 points.
- Why unverified: Stored-summary information, scope and gaps displayed; not completed content review or a new clinical verdict
- Reason for missing information: The selected row has no score, status or axes. Do not fill its score with parent values or create a new verdict.
- Required materials and conditions: Original wording, grade and note for maintained/restored work participation at 12 months
- Materials to obtain first: Subclaim and original parent verdict
- Further research: Distinguish the original verdict from this production and review of existing content
- Conditions for verification: Original wording, grade and note for maintained/restored work participation at 12 months; preserve only original values, direct observations, scope and gaps without creating new effects, verdicts, calculations or independence certification.
- Why this condition is needed: Production condition separating direct material and gaps for the selected time point, full cohort/subgroups and work outcome
- Application exceptions: Other time points, subgroups, questionnaires, services or denominators do not fill unresolved information in the selected material
- Remaining uncertainty: External abstracts, full texts, registration, protocol and SAP unread; no new calculations or clinical-content review performed
- Referenced methods: Linkage to preserved methodology-application records; full-definition content review and official certification incomplete
- Related sources: R01

### N02 · Do maintained/restored and maintained/increased have the same definition?

Verification status: Partly verified  
Reading scope: Summary read; related external material unread

- Current findings: The subclaim's stored wording says maintained/restored, while the existing reader answer says maintained/increased work participation. This concerns actual work outcomes in national records.
- Why unverified: Stored-summary information, scope and gaps displayed; not completed content review or a new clinical verdict
- Reason for missing information: Detailed baseline classifications and separate effects on restoration/maintenance are absent from the summary. Do not unify the two descriptions through an invented definition or change them into return to employment for every participant.
- Required materials and conditions: Original classifications of baseline work status, maintenance, restoration and increase
- Materials to obtain first: Original work-participation definition, baseline classifications and results by category
- Further research: Distinguish original wording from the component results for maintenance, restoration and increase
- Conditions for verification: Original classifications of baseline work status, maintenance, restoration and increase; preserve only original values, direct observations, scope and gaps without creating new effects, verdicts, calculations or independence certification.
- Why this condition is needed: Production condition separating direct material and gaps for the selected time point, full cohort/subgroups and work outcome
- Application exceptions: Other time points, subgroups, questionnaires, services or denominators do not fill unresolved information in the selected material
- Remaining uncertainty: External abstracts, full texts, registration, protocol and SAP unread; no new calculations or clinical-content review performed
- Referenced methods: Linkage to preserved methodology-application records; full-definition content review and official certification incomplete
- Related sources: R01

### N03 · Are the anxiety/depression population and high-risk exclusions distinguished?

Verification status: Partly verified  
Reading scope: Summary read; related external material unread

- Current findings: The parent's original outcome concerns 12-month work participation in adults with anxiety or depression. People at high suicide risk or with severe mental illness or active substance use were excluded.
- Why unverified: Stored-summary information, scope and gaps displayed; not completed content review or a new clinical verdict
- Reason for missing information: Do not generalize to all major depressive disorder, severe/high-risk cases or other ages/countries. Detailed diagnoses and baseline work/benefit status remain unread.
- Required materials and conditions: Diagnosis, baseline work/benefit status, eligibility and exclusions
- Materials to obtain first: Original eligibility, baseline and exclusion tables
- Further research: Distinguish the recruited population from excluded high-risk groups
- Conditions for verification: Diagnosis, baseline work/benefit status, eligibility and exclusions; preserve only original values, direct observations, scope and gaps without creating new effects, verdicts, calculations or independence certification.
- Why this condition is needed: Production condition separating direct material and gaps for the selected time point, full cohort/subgroups and work outcome
- Application exceptions: Other time points, subgroups, questionnaires, services or denominators do not fill unresolved information in the selected material
- Remaining uncertainty: External abstracts, full texts, registration, protocol and SAP unread; no new calculations or clinical-content review performed
- Referenced methods: Linkage to preserved methodology-application records; full-definition content review and official certification incomplete
- Related sources: R01

### N04 · What combined service was the intervention?

Verification status: Partly verified  
Reading scope: Summary read; related external material unread

- Current findings: The evidence concerns a combined Norwegian service offering up to 15 sessions of work-focused CBT and individual job support.
- Why unverified: Stored-summary information, scope and gaps displayed; not completed content review or a new clinical verdict
- Reason for missing information: Do not decompose this into effects of CBT alone, job support alone or other services. Do not create session, job-support or treatment instructions.
- Required materials and conditions: Work-focused CBT, individual job support, delivery organization and study exposure
- Materials to obtain first: Specifications of both components, delivery organization and actual exposure
- Further research: Distinguish the combined program's identity from questions about individual components/other services
- Conditions for verification: Work-focused CBT, individual job support, delivery organization and study exposure; preserve only original values, direct observations, scope and gaps without creating new effects, verdicts, calculations or independence certification.
- Why this condition is needed: Production condition separating direct material and gaps for the selected time point, full cohort/subgroups and work outcome
- Application exceptions: Other time points, subgroups, questionnaires, services or denominators do not fill unresolved information in the selected material
- Remaining uncertainty: External abstracts, full texts, registration, protocol and SAP unread; no new calculations or clinical-content review performed
- Referenced methods: Linkage to preserved methodology-application records; full-definition content review and official certification incomplete
- Related sources: R01

### N05 · Are actual usual-care content and concomitant exposures by arm known?

Verification status: Partly verified  
Reading scope: Summary read; related external material unread

- Current findings: The comparison is 630 AWaC participants versus 563 receiving usual care.
- Why unverified: Stored-summary information, scope and gaps displayed; not completed content review or a new clinical verdict
- Reason for missing information: Details of usual care, concomitant psychological/drug/employment exposures, crossover and changes are absent. Do not assert identical concomitant conditions or a pure CBT effect.
- Required materials and conditions: Usual care, concomitant treatment, benefit/employment services and changes
- Materials to obtain first: Arm-specific usual care, concomitant exposures and changes
- Further research: Distinguish the effect of assignment to the combined service from limitations of actual concomitant care
- Conditions for verification: Usual care, concomitant treatment, benefit/employment services and changes; preserve only original values, direct observations, scope and gaps without creating new effects, verdicts, calculations or independence certification.
- Why this condition is needed: Production condition separating direct material and gaps for the selected time point, full cohort/subgroups and work outcome
- Application exceptions: Other time points, subgroups, questionnaires, services or denominators do not fill unresolved information in the selected material
- Remaining uncertainty: External abstracts, full texts, registration, protocol and SAP unread; no new calculations or clinical-content review performed
- Referenced methods: Linkage to preserved methodology-application records; full-definition content review and official certification incomplete
- Related sources: R01

### N06 · What are the original allocation unit, centers and denominators?

Verification status: Partly verified  
Reading scope: Summary read; related external material unread

- Current findings: This was a pragmatic multicenter randomized trial assigning 1,193 participants at six Norwegian centers, 630/563 by arm.
- Why unverified: Stored-summary information, scope and gaps displayed; not completed content review or a new clinical verdict
- Reason for missing information: Do not count centers, arms or repeated monthly records as new participants or independent trials. Complete register follow-up differs from treatment completion.
- Required materials and conditions: Centers, randomization process, allocation by arm and denominators
- Materials to obtain first: Allocation, centers and participant flow
- Further research: Distinguish centers, allocated people and repeated-record units
- Conditions for verification: Centers, randomization process, allocation by arm and denominators; preserve only original values, direct observations, scope and gaps without creating new effects, verdicts, calculations or independence certification.
- Why this condition is needed: Production condition separating direct material and gaps for the selected time point, full cohort/subgroups and work outcome
- Application exceptions: Other time points, subgroups, questionnaires, services or denominators do not fill unresolved information in the selected material
- Remaining uncertainty: External abstracts, full texts, registration, protocol and SAP unread; no new calculations or clinical-content review performed
- Referenced methods: Linkage to preserved methodology-application records; full-definition content review and official certification incomplete
- Related sources: R01

### N07 · What is the scope of the original evidence on allocation and outcome masking?

Verification status: Partly verified  
Reading scope: Summary read; related external material unread

- Current findings: The stored summary includes the allocation statement about an independent researcher without participant/center-staff contact and objective register-based ascertainment. Participant masking was impossible for psychotherapy.
- Why unverified: Stored-summary information, scope and gaps displayed; not completed content review or a new clinical verdict
- Reason for missing information: Do not turn parent B0 or the quoted statements into completion of current methodology review. Original details of implementation, baseline balance and register processing are unread.
- Required materials and conditions: Independent allocator, participant masking and register-based ascertainment
- Materials to obtain first: Allocation, register-based ascertainment and measurement methods
- Further research: Distinguish original methods descriptions from this summary-reading scope
- Conditions for verification: Independent allocator, participant masking and register-based ascertainment; preserve only original values, direct observations, scope and gaps without creating new effects, verdicts, calculations or independence certification.
- Why this condition is needed: Production condition separating direct material and gaps for the selected time point, full cohort/subgroups and work outcome
- Application exceptions: Other time points, subgroups, questionnaires, services or denominators do not fill unresolved information in the selected material
- Remaining uncertainty: External abstracts, full texts, registration, protocol and SAP unread; no new calculations or clinical-content review performed
- Referenced methods: Linkage to preserved methodology-application records; full-definition content review and official certification incomplete
- Related sources: R01

### N08 · Which records established work participation?

Verification status: Partly verified  
Reading scope: Summary read; related external material unread

- Current findings: Monthly work and benefit status were determined from Norwegian national insurance and employment registers. These are actual outcomes distinct from questionnaire scores.
- Why unverified: Stored-summary information, scope and gaps displayed; not completed content review or a new clinical verdict
- Reason for missing information: Details of actual working hours, employment type, benefit classifications, linkage and error handling are unread. Do not say register data answer every clinical/work-performance question.
- Required materials and conditions: National insurance/employment registers and monthly work/benefit-status definitions
- Materials to obtain first: Register definitions, linkage and monthly ascertainment specifications
- Further research: Distinguish actual work outcomes from questionnaires and other functional outcomes
- Conditions for verification: National insurance/employment registers and monthly work/benefit-status definitions; preserve only original values, direct observations, scope and gaps without creating new effects, verdicts, calculations or independence certification.
- Why this condition is needed: Production condition separating direct material and gaps for the selected time point, full cohort/subgroups and work outcome
- Application exceptions: Other time points, subgroups, questionnaires, services or denominators do not fill unresolved information in the selected material
- Remaining uncertainty: External abstracts, full texts, registration, protocol and SAP unread; no new calculations or clinical-content review performed
- Referenced methods: Linkage to preserved methodology-application records; full-definition content review and official certification incomplete
- Related sources: R01

### N09 · What is the scope of zero loss to follow-up at 12 months?

Verification status: Partly verified  
Reading scope: Summary read; related external material unread

- Current findings: The original material states that 12-month results were obtained for all 1,193 participants and primary-outcome loss to follow-up was 0/1,193.
- Why unverified: Stored-summary information, scope and gaps displayed; not completed content review or a new clinical verdict
- Reason for missing information: Do not equate this with complete treatment/questionnaire participation, complete collection of every event or full long-term follow-up.
- Required materials and conditions: Primary outcome, register-data acquisition/linkage and missing data by arm
- Materials to obtain first: Original primary-outcome register follow-up, linkage and analysis tables
- Further research: Separate complete primary-outcome follow-up from denominators for other materials/time points
- Conditions for verification: Primary outcome, register-data acquisition/linkage and missing data by arm; preserve only original values, direct observations, scope and gaps without creating new effects, verdicts, calculations or independence certification.
- Why this condition is needed: Production condition separating direct material and gaps for the selected time point, full cohort/subgroups and work outcome
- Application exceptions: Other time points, subgroups, questionnaires, services or denominators do not fill unresolved information in the selected material
- Remaining uncertainty: External abstracts, full texts, registration, protocol and SAP unread; no new calculations or clinical-content review performed
- Referenced methods: Linkage to preserved methodology-application records; full-definition content review and official certification incomplete
- Related sources: R01

### N10 · Are original arm-specific proportions and the unadjusted difference preserved?

Verification status: Partly verified  
Reading scope: Summary read; related external material unread

- Current findings: Maintained/increased participation at 12 months was 44.2% versus 37.2%, unadjusted difference 6.9 percentage points, P=.015.
- Why unverified: Stored-summary information, scope and gaps displayed; not completed content review or a new clinical verdict
- Reason for missing information: Do not calculate new differences, event counts or NNT from the original proportions. Preserve the proportions and directly reported difference separately unchanged.
- Required materials and conditions: 44.2/37.2 and the directly reported unadjusted difference/P
- Materials to obtain first: Original proportions, unadjusted estimate and denominator tables
- Further research: Display rounded proportions separately from the directly reported difference
- Conditions for verification: 44.2/37.2 and the directly reported unadjusted difference/P; preserve only original values, direct observations, scope and gaps without creating new effects, verdicts, calculations or independence certification.
- Why this condition is needed: Production condition separating direct material and gaps for the selected time point, full cohort/subgroups and work outcome
- Application exceptions: Other time points, subgroups, questionnaires, services or denominators do not fill unresolved information in the selected material
- Remaining uncertainty: External abstracts, full texts, registration, protocol and SAP unread; no new calculations or clinical-content review performed
- Referenced methods: Linkage to preserved methodology-application records; full-definition content review and official certification incomplete
- Related sources: R01

### N11 · What is the prespecified covariate-adjusted marginal effect?

Verification status: Partly verified  
Reading scope: Summary read; related external material unread

- Current findings: The described prespecified covariate-adjusted marginal effect is +6.2 percentage points, 95% CI +0.5~+11.8.
- Why unverified: Stored-summary information, scope and gaps displayed; not completed content review or a new clinical verdict
- Reason for missing information: Do not merge the unadjusted 6.9-percentage-point difference with the adjusted effect. Exact models, covariates and estimands are externally unread; do not create new effects or CIs.
- Required materials and conditions: Adjusted estimate, CI, covariates and effect of interest
- Materials to obtain first: Original adjustment model, marginal effect and planning material
- Further research: Separate original proportions, unadjusted and adjusted effects
- Conditions for verification: Adjusted estimate, CI, covariates and effect of interest; preserve only original values, direct observations, scope and gaps without creating new effects, verdicts, calculations or independence certification.
- Why this condition is needed: Production condition separating direct material and gaps for the selected time point, full cohort/subgroups and work outcome
- Application exceptions: Other time points, subgroups, questionnaires, services or denominators do not fill unresolved information in the selected material
- Remaining uncertainty: External abstracts, full texts, registration, protocol and SAP unread; no new calculations or clinical-content review performed
- Referenced methods: Linkage to preserved methodology-application records; full-definition content review and official certification incomplete
- Related sources: R01

### N12 · Does the analysis answer assignment, actual participation or completers?

Verification status: Partly verified  
Reading scope: Summary read; related external material unread

- Current findings: The existing evidence list supplies a 12-month comparison of the originally randomized 1,193 participants with complete register follow-up.
- Why unverified: Stored-summary information, scope and gaps displayed; not completed content review or a new clinical verdict
- Reason for missing information: Do not establish detailed models, effects of actual treatment adherence or individual components. Complete register follow-up does not mean everyone participated in the intervention.
- Required materials and conditions: Analysis population, effect of interest, concomitant exposures and imputation/exclusions
- Materials to obtain first: Original analysis models, actual participation and changes by arm
- Further research: Distinguish assignment comparisons from adherence/completer effects
- Conditions for verification: Analysis population, effect of interest, concomitant exposures and imputation/exclusions; preserve only original values, direct observations, scope and gaps without creating new effects, verdicts, calculations or independence certification.
- Why this condition is needed: Production condition separating direct material and gaps for the selected time point, full cohort/subgroups and work outcome
- Application exceptions: Other time points, subgroups, questionnaires, services or denominators do not fill unresolved information in the selected material
- Remaining uncertainty: External abstracts, full texts, registration, protocol and SAP unread; no new calculations or clinical-content review performed
- Referenced methods: Linkage to preserved methodology-application records; full-definition content review and official certification incomplete
- Related sources: R01

### N13 · Are low session attendance and work-outcome follow-up distinguished?

Verification status: Partly verified  
Reading scope: Summary read; related external material unread

- Current findings: Preserve the Korean safety statement describing 5% of AWaC participants stopping treatment before three sessions and the English original describing attendance at fewer than three sessions.
- Why unverified: Stored-summary information, scope and gaps displayed; not completed content review or a new clinical verdict
- Reason for missing information: Do not calculate participant counts from 5% or turn it into clinical harm or total follow-up loss. Reasons, exposure and discontinuation differ from work records.
- Required materials and conditions: Treatment attendance, discontinuation, reasons/timing and register follow-up
- Materials to obtain first: Treatment attendance/discontinuation, reasons and register-data flow
- Further research: Distinguish treatment participation from primary work-outcome follow-up
- Conditions for verification: Treatment attendance, discontinuation, reasons/timing and register follow-up; preserve only original values, direct observations, scope and gaps without creating new effects, verdicts, calculations or independence certification.
- Why this condition is needed: Production condition separating direct material and gaps for the selected time point, full cohort/subgroups and work outcome
- Application exceptions: Other time points, subgroups, questionnaires, services or denominators do not fill unresolved information in the selected material
- Remaining uncertainty: External abstracts, full texts, registration, protocol and SAP unread; no new calculations or clinical-content review performed
- Referenced methods: Linkage to preserved methodology-application records; full-definition content review and official certification incomplete
- Related sources: R01

### N14 · Were the 12-month primary outcome, prespecified adjustment and planning material actually read?

Verification status: Partly verified  
Reading scope: Summary read; related external material unread

- Current findings: The original summary describes agreement of the objective 12-month work-participation primary outcome with NCT01146730 and prespecified adjustment. A registration citation link is also present.
- Why unverified: Stored-summary information, scope and gaps displayed; not completed content review or a new clinical verdict
- Reason for missing information: Registration text/dates, protocol, SAP, multiplicity and amendment history are unread. A URL does not establish completion of review of prespecification.
- Required materials and conditions: NCT, primary outcome, prespecified models, protocol, SAP and history
- Materials to obtain first: Registration, plans before recruitment, SAP and amendment documents
- Further research: Distinguish preserved prespecified-planning descriptions from actual external reading
- Conditions for verification: NCT, primary outcome, prespecified models, protocol, SAP and history; preserve only original values, direct observations, scope and gaps without creating new effects, verdicts, calculations or independence certification.
- Why this condition is needed: Production condition separating direct material and gaps for the selected time point, full cohort/subgroups and work outcome
- Application exceptions: Other time points, subgroups, questionnaires, services or denominators do not fill unresolved information in the selected material
- Remaining uncertainty: External abstracts, full texts, registration, protocol and SAP unread; no new calculations or clinical-content review performed
- Referenced methods: Linkage to preserved methodology-application records; full-definition content review and official certification incomplete
- Related sources: R01, R03

### N15 · Has clinical/work importance of maintenance/restoration been newly defined?

Verification status: Partly verified  
Reading scope: Summary read; related external material unread

- Current findings: Original proportions and effects directly concern work participation at 12 months.
- Why unverified: Stored-summary information, scope and gaps displayed; not completed content review or a new clinical verdict
- Reason for missing information: Do not create minimally important clinical differences, working hours, employment quality, individual examples or economic effects absent from the summary. Actual work events do not answer every other life outcome.
- Required materials and conditions: Prespecified importance, working hours, job satisfaction, income and functional criteria
- Materials to obtain first: Direct results on importance, working hours, function and economic outcomes
- Further research: Distinguish statistical comparisons from gaps in importance and other outcomes
- Conditions for verification: Prespecified importance, working hours, job satisfaction, income and functional criteria; preserve only original values, direct observations, scope and gaps without creating new effects, verdicts, calculations or independence certification.
- Why this condition is needed: Production condition separating direct material and gaps for the selected time point, full cohort/subgroups and work outcome
- Application exceptions: Other time points, subgroups, questionnaires, services or denominators do not fill unresolved information in the selected material
- Remaining uncertainty: External abstracts, full texts, registration, protocol and SAP unread; no new calculations or clinical-content review performed
- Referenced methods: Linkage to preserved methodology-application records; full-definition content review and official certification incomplete
- Related sources: R01

### N16 · Has the 18-month observation been transferred into 12-month or long-term effects?

Verification status: Partly verified  
Reading scope: Summary read; related external material unread

- Current findings: The original product information also records an 18-month observed difference of +7.8 percentage points, P=.018.
- Why unverified: Stored-summary information, scope and gaps displayed; not completed content review or a new clinical verdict
- Reason for missing information: The summary has no 18-month CI, denominator or adjustment status. Do not change this into the 12-month adjusted value or long-term full-cohort confirmation.
- Required materials and conditions: Comparisons, denominators, observation and analysis by time point
- Materials to obtain first: 18-month analysis, denominators and intervals
- Further research: Display 12/18-month and long-term extension results separately
- Conditions for verification: Comparisons, denominators, observation and analysis by time point; preserve only original values, direct observations, scope and gaps without creating new effects, verdicts, calculations or independence certification.
- Why this condition is needed: Production condition separating direct material and gaps for the selected time point, full cohort/subgroups and work outcome
- Application exceptions: Other time points, subgroups, questionnaires, services or denominators do not fill unresolved information in the selected material
- Remaining uncertainty: External abstracts, full texts, registration, protocol and SAP unread; no new calculations or clinical-content review performed
- Referenced methods: Linkage to preserved methodology-application records; full-definition content review and official certification incomplete
- Related sources: R01, R02

### N17 · Has a favorable short-term result filled in the null full-cohort result at 10~46 months?

Verification status: Partly verified  
Reading scope: Summary read; related external material unread

- Current findings: The same-cohort 10~46-month extension records no significant full-cohort differences in income, work participation or months without benefits.
- Why unverified: Stored-summary information, scope and gaps displayed; not completed content review or a new clinical verdict
- Reason for missing information: Do not copy the 12-month +6.2-percentage-point result as sustained full-cohort benefit or certify a null result as exactly zero/equivalence.
- Required materials and conditions: Direct long-term full-cohort effects and denominators by outcome
- Materials to obtain first: Original long-term full-cohort results/follow-up by outcome
- Further research: Distinguish favorable short-term from null long-term results
- Conditions for verification: Direct long-term full-cohort effects and denominators by outcome; preserve only original values, direct observations, scope and gaps without creating new effects, verdicts, calculations or independence certification.
- Why this condition is needed: Production condition separating direct material and gaps for the selected time point, full cohort/subgroups and work outcome
- Application exceptions: Other time points, subgroups, questionnaires, services or denominators do not fill unresolved information in the selected material
- Remaining uncertainty: External abstracts, full texts, registration, protocol and SAP unread; no new calculations or clinical-content review performed
- Referenced methods: Linkage to preserved methodology-application records; full-definition content review and official certification incomplete
- Related sources: R01, R02

### N18 · Has the signal in long-term benefit recipients been expanded to the full cohort?

Verification status: Partly verified  
Reading scope: Summary read; related external material unread

- Current findings: The long-term extension summary states significance only in the long-term-benefit subgroup.
- Why unverified: Stored-summary information, scope and gaps displayed; not completed content review or a new clinical verdict
- Reason for missing information: Exact subgroup criteria, effects, denominators, plans and interactions are absent. Do not promote this signal to sustained full-cohort superiority.
- Required materials and conditions: Subgroup definition, plans, denominators, effects and interactions
- Materials to obtain first: Original subgroup plans, definitions, effects and interaction tables
- Further research: Display full-cohort and subgroup direct results separately
- Conditions for verification: Subgroup definition, plans, denominators, effects and interactions; preserve only original values, direct observations, scope and gaps without creating new effects, verdicts, calculations or independence certification.
- Why this condition is needed: Production condition separating direct material and gaps for the selected time point, full cohort/subgroups and work outcome
- Application exceptions: Other time points, subgroups, questionnaires, services or denominators do not fill unresolved information in the selected material
- Remaining uncertainty: External abstracts, full texts, registration, protocol and SAP unread; no new calculations or clinical-content review performed
- Referenced methods: Linkage to preserved methodology-application records; full-definition content review and official certification incomplete
- Related sources: R02

### N19 · Are same-cohort long-term reports, registration and the two sheets independent replication?

Verification status: Partly verified  
Reading scope: Summary read; related external material unread

- Current findings: The main AWaC report, long-term report and registration concern the same trial; both selected questions share the stored verdict 2954 summary.
- Why unverified: Stored-summary information, scope and gaps displayed; not completed content review or a new clinical verdict
- Reason for missing information: Do not aggregate three citation entries, two sheets, monthly records, centers or time points into new independent trials/participants. Confirmed counts remain null.
- Required materials and conditions: Linkage of original trial, extension, registration, participants and time points
- Materials to obtain first: Report, registration, time-point and participant linkage material
- Further research: Separate citation entries from actual trial/participant units
- Conditions for verification: Linkage of original trial, extension, registration, participants and time points; preserve only original values, direct observations, scope and gaps without creating new effects, verdicts, calculations or independence certification.
- Why this condition is needed: Production condition separating direct material and gaps for the selected time point, full cohort/subgroups and work outcome
- Application exceptions: Other time points, subgroups, questionnaires, services or denominators do not fill unresolved information in the selected material
- Remaining uncertainty: External abstracts, full texts, registration, protocol and SAP unread; no new calculations or clinical-content review performed
- Referenced methods: Linkage to preserved methodology-application records; full-definition content review and official certification incomplete
- Related sources: R01, R02, R03

### N20 · Has complete 12-month follow-up been reused as the long-term analysis denominator?

Verification status: Partly verified  
Reading scope: Summary read; related external material unread

- Current findings: Acquisition of outcomes for all 1,193 participants and zero loss are original statements about the 12-month primary outcome.
- Why unverified: Stored-summary information, scope and gaps displayed; not completed content review or a new clinical verdict
- Reason for missing information: Do not fill the exact long-term full-cohort analysis/follow-up denominators with those same values. Detailed long-term reporting is externally unread.
- Required materials and conditions: Measured, analyzed, linked and lost denominators at 10~46 months
- Materials to obtain first: Long-term denominators, register linkage and analysis tables
- Further research: Separate actual observation/analysis scope by time point
- Conditions for verification: Measured, analyzed, linked and lost denominators at 10~46 months; preserve only original values, direct observations, scope and gaps without creating new effects, verdicts, calculations or independence certification.
- Why this condition is needed: Production condition separating direct material and gaps for the selected time point, full cohort/subgroups and work outcome
- Application exceptions: Other time points, subgroups, questionnaires, services or denominators do not fill unresolved information in the selected material
- Remaining uncertainty: External abstracts, full texts, registration, protocol and SAP unread; no new calculations or clinical-content review performed
- Referenced methods: Linkage to preserved methodology-application records; full-definition content review and official certification incomplete
- Related sources: R02

### N21 · Have different delivery systems/vocational-advice verdicts been merged as the same effect?

Verification status: Partly verified  
Reading scope: Summary read; related external material unread

- Current findings: The existing advertising interpretation says AWaC differs in delivery system/population from physiotherapist vocational advice in verdict 2944, B with 72 points. The related path is preserved in the summary.
- Why unverified: Stored-summary information, scope and gaps displayed; not completed content review or a new clinical verdict
- Reason for missing information: Do not newly retrieve/check that verdict or link. Do not combine another service's effects or count it as independent replication.
- Required materials and conditions: Actual comparisons of the combined service, populations and delivery systems
- Materials to obtain first: Direct comparison material by delivery system/population
- Further research: Preserve only the original related context and distinguish service-specific questions
- Conditions for verification: Actual comparisons of the combined service, populations and delivery systems; preserve only original values, direct observations, scope and gaps without creating new effects, verdicts, calculations or independence certification.
- Why this condition is needed: Production condition separating direct material and gaps for the selected time point, full cohort/subgroups and work outcome
- Application exceptions: Other time points, subgroups, questionnaires, services or denominators do not fill unresolved information in the selected material
- Remaining uncertainty: External abstracts, full texts, registration, protocol and SAP unread; no new calculations or clinical-content review performed
- Referenced methods: Linkage to preserved methodology-application records; full-definition content review and official certification incomplete
- Related sources: R01

### N22 · Are public funding, center operation and evaluator roles distinguished?

Verification status: Partly verified  
Reading scope: Summary read; related external material unread

- Current findings: The Korean summary records full funding by the Health and Labour Ministries through the National Strategy on Work and Mental Health, NAV center operation, and independent evaluators uninvolved in center operation/treatment.
- Why unverified: Stored-summary information, scope and gaps displayed; not completed content review or a new clinical verdict
- Reason for missing information: Do not merge funding, operational and evaluator roles or convert them to current independence certification. Complete authority/disclosures remain unread.
- Required materials and conditions: Health/Labour Ministries, NAV and evaluator roles/authority
- Materials to obtain first: Funding, operational/evaluation roles and data-authority disclosures
- Further research: Display public support, service operation and evaluator roles separately
- Conditions for verification: Health/Labour Ministries, NAV and evaluator roles/authority; preserve only original values, direct observations, scope and gaps without creating new effects, verdicts, calculations or independence certification.
- Why this condition is needed: Production condition separating direct material and gaps for the selected time point, full cohort/subgroups and work outcome
- Application exceptions: Other time points, subgroups, questionnaires, services or denominators do not fill unresolved information in the selected material
- Remaining uncertainty: External abstracts, full texts, registration, protocol and SAP unread; no new calculations or clinical-content review performed
- Referenced methods: Linkage to preserved methodology-application records; full-definition content review and official certification incomplete
- Related sources: R01

### N23 · Are complete disclosures of author, analysis, writing and publication support available?

Verification status: Unverified  
Reading scope: Summary read; related external material unread

- Current findings: The stored summary describes public funding, NAV operation and evaluation independence.
- Why unverified: Stored-summary information, scope and gaps displayed; not completed content review or a new clinical verdict
- Reason for missing information: Do not certify every unmentioned item as absent, including company product support, employee authors, outsourced analysis, writing or publication fees.
- Required materials and conditions: Author relationships, analysis, medical writing, publication and data/publication authority
- Materials to obtain first: Author/supporter, data and publication disclosures
- Further research: Distinguish known roles from unverified complete disclosures
- Conditions for verification: Author relationships, analysis, medical writing, publication and data/publication authority; preserve only original values, direct observations, scope and gaps without creating new effects, verdicts, calculations or independence certification.
- Why this condition is needed: Production condition separating direct material and gaps for the selected time point, full cohort/subgroups and work outcome
- Application exceptions: Other time points, subgroups, questionnaires, services or denominators do not fill unresolved information in the selected material
- Remaining uncertainty: External abstracts, full texts, registration, protocol and SAP unread; no new calculations or clinical-content review performed
- Referenced methods: Linkage to preserved methodology-application records; full-definition content review and official certification incomplete
- Related sources: R01

### N24 · Were prespecified safety outcomes or serious-adverse-event tables reported?

Verification status: Partly verified  
Reading scope: Summary read; related external material unread

- Current findings: The existing safety explanation states no prespecified safety outcome or serious-adverse-event comparison table was reported.
- Why unverified: Stored-summary information, scope and gaps displayed; not completed content review or a new clinical verdict
- Reason for missing information: Do not turn unverified harms into zero events, service safety or equivalence to control. Complete register work-outcome follow-up differs from complete harm collection.
- Required materials and conditions: Harm plans, definitions, collection, arm-specific events and denominators
- Materials to obtain first: Harm plans, arm-specific events, exposure and discontinuation tables
- Further research: Distinguish acquisition of work records from safety-data collection
- Conditions for verification: Harm plans, definitions, collection, arm-specific events and denominators; preserve only original values, direct observations, scope and gaps without creating new effects, verdicts, calculations or independence certification.
- Why this condition is needed: Supplementary condition revealing harm collection, exposure and population scope separately from efficacy
- Application exceptions: Other time points, subgroups, questionnaires, services or denominators do not fill unresolved information in the selected material
- Remaining uncertainty: External abstracts, full texts, registration, protocol and SAP unread; no new calculations or clinical-content review performed
- Referenced methods: Linkage to preserved methodology-application records; full-definition content review and official certification incomplete
- Related sources: R01

### N25 · Can high-risk exclusions and 5% low attendance certify harms?

Verification status: Partly verified  
Reading scope: Summary read; related external material unread

- Current findings: Original information excludes high suicide risk, severe mental illness and active substance use, and describes 5% of AWaC participants stopping before three treatment sessions.
- Why unverified: Stored-summary information, scope and gaps displayed; not completed content review or a new clinical verdict
- Reason for missing information: Do not calculate harm incidence from 5% or fill in safety/treatment efficacy for excluded groups. Do not create new treatment instructions.
- Required materials and conditions: High-risk groups, discontinuation reasons, events, causes and follow-up
- Materials to obtain first: Excluded populations, attendance/discontinuation reasons and event data
- Further research: Distinguish intervention participation from harms and applicability limits
- Conditions for verification: High-risk groups, discontinuation reasons, events, causes and follow-up; preserve only original values, direct observations, scope and gaps without creating new effects, verdicts, calculations or independence certification.
- Why this condition is needed: Supplementary condition revealing harm collection, exposure and population scope separately from efficacy
- Application exceptions: Other time points, subgroups, questionnaires, services or denominators do not fill unresolved information in the selected material
- Remaining uncertainty: External abstracts, full texts, registration, protocol and SAP unread; no new calculations or clinical-content review performed
- Referenced methods: Linkage to preserved methodology-application records; full-definition content review and official certification incomplete
- Related sources: R01

### N26 · Do long-term/rare harms and clinical symptoms require separate evidence?

Verification status: Unverified  
Reading scope: Summary read; related external material unread

- Current findings: Original safety is Unknown; primary work outcomes and the long-term work extension are separate.
- Why unverified: Stored-summary information, scope and gaps displayed; not completed content review or a new clinical verdict
- Reason for missing information: Favorable work-participation results or null long-term results cannot establish mental-health cure, long-term safety or absence of rare harms.
- Required materials and conditions: Long-term exposure, events, symptoms, function and follow-up denominators
- Materials to obtain first: Direct material on long-term harms, clinical symptoms and function
- Further research: Separate work participation from gaps in clinical/safety outcomes
- Conditions for verification: Long-term exposure, events, symptoms, function and follow-up denominators; preserve only original values, direct observations, scope and gaps without creating new effects, verdicts, calculations or independence certification.
- Why this condition is needed: Supplementary condition revealing harm collection, exposure and population scope separately from efficacy
- Application exceptions: Other time points, subgroups, questionnaires, services or denominators do not fill unresolved information in the selected material
- Remaining uncertainty: External abstracts, full texts, registration, protocol and SAP unread; no new calculations or clinical-content review performed
- Referenced methods: Linkage to preserved methodology-application records; full-definition content review and official certification incomplete
- Related sources: R01, R02

### N27 · Is actual summary reading distinguished from unread external papers/registration?

Verification status: Partly verified  
Reading scope: Summary read; related external material unread

- Current findings: The complete parent stored summary was read. Main/long-term PubMed URLs and the official registration URL are linked as original citations.
- Why unverified: Stored-summary information, scope and gaps displayed; not completed content review or a new clinical verdict
- Reason for missing information: External abstracts, full texts, registration, protocol, SAP, links and screens were not read/checked. A URL's presence does not establish reading or quality certification.
- Required materials and conditions: Each citation, original registration URL, preservation and access status
- Materials to obtain first: Main/long-term reports, registration and planning material
- Further research: Display summary reading separately from unread external material by type
- Conditions for verification: Each citation, original registration URL, preservation and access status; preserve only original values, direct observations, scope and gaps without creating new effects, verdicts, calculations or independence certification.
- Why this condition is needed: Production condition separating direct material and gaps for the selected time point, full cohort/subgroups and work outcome
- Application exceptions: Other time points, subgroups, questionnaires, services or denominators do not fill unresolved information in the selected material
- Remaining uncertainty: External abstracts, full texts, registration, protocol and SAP unread; no new calculations or clinical-content review performed
- Referenced methods: Linkage to preserved methodology-application records; full-definition content review and official certification incomplete
- Related sources: R01, R02, R03

### N28 · Are original history/selected-verdict linkage separated from production and content review?

Verification status: Partly verified  
Reading scope: Summary read; related external material unread

- Current findings: Preserve parent Korean/English text, axes, reference date 2026-08-26, empty corrections/deliberation and the selected row within the whole stored summary. Original candidate review-pending/production-eligibility flags are historical.
- Why unverified: Stored-summary information, scope and gaps displayed; not completed content review or a new clinical verdict
- Reason for missing information: Keep absent subclaim score/status/axes and the reference date; do not activate review waiting. Existing-content review remains incomplete, completion flags false, new units 0 and confirmed independence count unrecorded.
- Required materials and conditions: Parent Korean/English text, axes, dates, corrections, selected row and freezing/application
- Materials to obtain first: Original stored summary, existing selection and condition/application events
- Further research: Record original verdicts/corrections separately from production and review of existing content
- Conditions for verification: Parent Korean/English text, axes, dates, corrections, selected row and freezing/application; preserve only original values, direct observations, scope and gaps without creating new effects, verdicts, calculations or independence certification.
- Why this condition is needed: Production condition separating direct material and gaps for the selected time point, full cohort/subgroups and work outcome
- Application exceptions: Other time points, subgroups, questionnaires, services or denominators do not fill unresolved information in the selected material
- Remaining uncertainty: External abstracts, full texts, registration, protocol and SAP unread; no new calculations or clinical-content review performed
- Referenced methods: Linkage to preserved methodology-application records; full-definition content review and official certification incomplete
- Related sources: R01, R02, R03

## Evidence and sources

### R01

Reme SE, et al. Occup Environ Med. 2015. PMID: 26251065.

[PubMed](https://pubmed.ncbi.nlm.nih.gov/26251065/)

Materials actually read: Summary read; external abstracts, full texts, registration and plans unread  
Findings recorded in the summary: The grade is B with 76 points. In AWaC, maintained/increased work participation at 12 months was 44.2% versus 37.2%, unadjusted difference 6.9 percentage points (P=.015), and prespecified covariate-adjusted marginal effect +6.2 percentage points (95% CI +0.5~+11.8).  
Record level: AWaC objective 12-month work participation; original proportions/unadjusted/adjusted effects and complete register follow-up for the primary outcome  
Independent replication: Main/long-term AWaC reports and registration linked by the original stored summary; three citations, repeated monthly records, arms and sibling sheets are not totaled as new trials/participants

| Material | Public availability | Access status | Actually read | Notes |
|---|---|---|---|---|
| Stored summary | Summary read | Stored summary read | Summary read | Material entries do not establish external acquisition, reading, checked links or unique-trial/participant certification; the official registration URL is linked only to its registration entry |
| External abstract | Not read | External material unread | Not read | Material entries do not establish external acquisition, reading, checked links or unique-trial/participant certification; the official registration URL is linked only to its registration entry |
| External full text | Not read | External material unread | Not read | Material entries do not establish external acquisition, reading, checked links or unique-trial/participant certification; the official registration URL is linked only to its registration entry |
| Original registration | Not read | External material unread | Not read | Material entries do not establish external acquisition, reading, checked links or unique-trial/participant certification; the official registration URL is linked only to its registration entry |
| Protocol/SAP | Not read | External material unread | Not read | Material entries do not establish external acquisition, reading, checked links or unique-trial/participant certification; the official registration URL is linked only to its registration entry |

### R02

Long-term effects on income and sickness benefits after work-focused CBT and individual job support. PMID: 30032103.

[PubMed](https://pubmed.ncbi.nlm.nih.gov/30032103/)

Materials actually read: Summary read; external abstracts, full texts, registration and plans unread  
Findings recorded in the summary: The same-cohort 10~46-month extension found no significant full-cohort differences in income, work participation or months without benefits; only the long-term-benefit subgroup was significant. The established result concerns the full cohort at 12 months, not persistence of effect.  
Record level: Same AWaC 10~46-month extension: null full-cohort results and long-term-benefit subgroup context; long-term denominators/original values unverified  
Independent replication: Main/long-term AWaC reports and registration linked by the original stored summary; three citations, repeated monthly records, arms and sibling sheets are not totaled as new trials/participants

| Material | Public availability | Access status | Actually read | Notes |
|---|---|---|---|---|
| Stored summary | Summary read | Stored summary read | Summary read | Material entries do not establish external acquisition, reading, checked links or unique-trial/participant certification; the official registration URL is linked only to its registration entry |
| External abstract | Not read | External material unread | Not read | Material entries do not establish external acquisition, reading, checked links or unique-trial/participant certification; the official registration URL is linked only to its registration entry |
| External full text | Not read | External material unread | Not read | Material entries do not establish external acquisition, reading, checked links or unique-trial/participant certification; the official registration URL is linked only to its registration entry |
| Original registration | Not read | External material unread | Not read | Material entries do not establish external acquisition, reading, checked links or unique-trial/participant certification; the official registration URL is linked only to its registration entry |
| Protocol/SAP | Not read | External material unread | Not read | Material entries do not establish external acquisition, reading, checked links or unique-trial/participant certification; the official registration URL is linked only to its registration entry |

### R03

NCT01146730. At Work and Coping.

[Official source](https://clinicaltrials.gov/study/NCT01146730)

Materials actually read: Summary read; external abstracts, full texts, registration and plans unread  
Findings recorded in the summary: Trial registration material.  
Record level: Same AWaC registration citation; original planning text unread, not a new clinical results report  
Independent replication: Main/long-term AWaC reports and registration linked by the original stored summary; three citations, repeated monthly records, arms and sibling sheets are not totaled as new trials/participants

| Material | Public availability | Access status | Actually read | Notes |
|---|---|---|---|---|
| Stored summary | Summary read | Stored summary read | Summary read | Material entries do not establish external acquisition, reading, checked links or unique-trial/participant certification; the official registration URL is linked only to its registration entry |
| External abstract | Not read | External material unread | Not read | Material entries do not establish external acquisition, reading, checked links or unique-trial/participant certification; the official registration URL is linked only to its registration entry |
| External full text | Not read | External material unread | Not read | Material entries do not establish external acquisition, reading, checked links or unique-trial/participant certification; the official registration URL is linked only to its registration entry |
| Original registration | Not read | External material unread | Not read | Material entries do not establish external acquisition, reading, checked links or unique-trial/participant certification; the official registration URL is linked only to its registration entry |
| Protocol/SAP | Not read | External material unread | Not read | Material entries do not establish external acquisition, reading, checked links or unique-trial/participant certification; the official registration URL is linked only to its registration entry |

## Review criteria and methods

These are Chamgap's own application conditions, informed by the relevant sections of official methodological guidance. They do not constitute official assessment-tool certification or a new efficacy score.

- M03 [Cochrane Handbook 6.5 (2024), chapter updated 2023-08](https://www.cochrane.org/authors/handbooks-and-manuals/handbook/current/chapter-03) · §3.1, §3.2.1–3.2.3, MECIR C5/C7/C13 · Clearly record the question, eligibility conditions and reasons for changes, and distinguish variations in interventions. · Preserved methodological linkages reused for production; no current methodological reassessment or external link checks, and historical quality review is not inherited
- M04 [Cochrane Handbook 6.5.1 (2025), chapter updated 2025-03](https://www.cochrane.org/authors/handbooks-and-manuals/handbook/current/chapter-04) · §4.5, §4.6.1–4.6.3, MECIR C42 · Distinguish studies from reports and link them; do not omit a study solely because results are unreported. · Preserved methodological linkages reused for production; no current methodological reassessment or external link checks, and historical quality review is not inherited
- M08 [Cochrane Handbook 6.5 (2024), chapter updated 2019-10](https://www.cochrane.org/authors/handbooks-and-manuals/handbook/current/chapter-08) · §8.1–8.2.3, Table 8.2.a · Define the outcome and effect of interest, then examine randomization, deviations, missing data, measurement and selective reporting. · Preserved methodological linkages reused for production; no current methodological reassessment or external link checks, and historical quality review is not inherited
- M15 [Cochrane Handbook 6.5 (2024), chapter updated 2023-08](https://www.cochrane.org/authors/handbooks-and-manuals/handbook/current/chapter-15) · §15.2.4, §15.3.1–15.3.3 · Distinguish effect estimates, intervals, importance and applicability. Sample size alone does not determine precision. · Preserved methodological linkages reused for production; no current methodological reassessment or external link checks, and historical quality review is not inherited
- M19 [Cochrane Handbook 6.5 (2024), chapter updated 2019-10](https://www.cochrane.org/authors/handbooks-and-manuals/handbook/current/chapter-19) · §19.1.2, §19.2.1–19.2.4 · Harm questions may require different designs, populations and follow-up from efficacy questions. Case reports do not establish incidence rates. · Preserved methodological linkages reused for production; no current methodological reassessment or external link checks, and historical quality review is not inherited

## What the statuses mean

- Partly verified: Some information exists in the preserved review summary; detailed original materials remain unverified. This does not certify a passed review or clinical efficacy.
- Unverified: Detailed materials for the selected condition could not be established within the stored scope; this does not mean zero effect, zero studies or safety
- Review incomplete: Review of existing content incomplete
- Met: Use only within the relevant conditions after existing content review; no automatic designation in this preparation
- Not reported: Distinguish only within materials actually read; do not turn unread external materials into unreported findings
- Inaccessible: Not applied during this preparation because actual access was not tested
- Not applicable: Use with a reason for non-applicability based on an explicit question boundary
- Conflicting data: Judge after actual material comparison; review was not performed during this preparation
- Insufficient evidence for the conditions: Do not use as a clinical grade encompassing currently unread materials

## Change history

2026-10-12 · Public page/materials 1.0. Public reader pages and material were prepared from the existing 28 items. No new clinical searches, verification-state changes or scoring were performed.