# Work-focused CBT and job support × Durable benefit in the full cohort — Evidence Check

Verdict 2954 · Evidence Check

Stored-material review date: Not recorded  
Original evidence cut-off: 2026-08-26  
Review-criteria version: 1.0  
Public page/material preparation date: 2026-10-12

Clinical papers were not read directly; existing review summaries were checked. No new clinical-literature search was performed. Unverified does not mean that research is absent or that there is no effect.

## Assessment scope

- Population: 1,193 adults with anxiety/depression randomized at six Norwegian centers (630/563); high suicide risk, severe mental illness and active substance use excluded; exact long-term denominators separately unverified
- Ingredient, formulation and route: Combined AWaC service with up to 15 sessions of work-focused CBT and individual job support
- Dose: Original study-service exposure context, not treatment/job-support implementation instructions; actual participation and subsequent exposure details unverified
- Comparator: Usual care; details of concomitant/additional treatments and arm-specific changes unread
- Measured outcome: Full-cohort income, work participation and months without benefits over 10 to 46 months; separate from the long-term-benefit subgroup
- Duration: Separate the original 12-month primary outcome, 18-month observations and 10-to-46-month extension results
- Questions outside this scope: No new evidence, effects, CIs, calculations, verdicts, independence certification, participant totals, psychological treatment/job-support/drug changes or treatment instructions are created

## Checklist items

### N01 · What are the original long-term full-cohort claim and subclaim verdict?

Verification status: Partly verified  
Reading scope: Summary read; related external material unread

- Current findings: The selected row concerns the long-term full-cohort effect, carries original grade D and notes a null full-cohort extension over 10 to 46 months. The parent concerns 12 months, grade B with 76 points.
- Why unverified: Stored-summary information, scope and gaps displayed; not completed content review or a new clinical verdict
- Reason for missing information: The selected row has no score, status or axes. Do not fill these with the parent B, 76 points or E+, or treat them as long-term effects.
- Required materials and conditions: Long-term full-cohort question, grade, note and parent context
- Materials to obtain first: Selected row and original parent verdict
- Further research: Distinguish the original long-term verdict from the 12-month context
- Conditions for verification: Long-term full-cohort question, grade, note and parent context; preserve only original values, direct observations, scope and gaps without creating new effects, verdicts, calculations or independence certification.
- Why this condition is needed: Production condition separating direct material and gaps for the selected time point, full cohort/subgroups and work outcome
- Application exceptions: Other time points, subgroups, questionnaires, services or denominators do not fill unresolved information in the selected material
- Remaining uncertainty: External abstracts, full texts, registration, protocol and SAP unread; no new calculations or clinical-content review performed
- Referenced methods: Linkage to preserved methodology-application records; full-definition content review and official certification incomplete
- Related sources: R02

### N02 · Which recruitment and analysis populations does the long-term full cohort refer to?

Verification status: Partly verified  
Reading scope: Summary read; related external material unread

- Current findings: The original trial randomized 1,193 adults with anxiety/depression (630/563); the extension analyzes the same cohort.
- Why unverified: Stored-summary information, scope and gaps displayed; not completed content review or a new clinical verdict
- Reason for missing information: Exact long-term analysis/follow-up denominators and eligibility details are absent from the summary. Do not certify the randomized total as the long-term observed or analyzed denominator.
- Required materials and conditions: Original allocation, extension eligibility, full cohort, subgroups and denominators
- Materials to obtain first: Long-term full-cohort participant flow, eligibility and analysis tables
- Further research: Present original allocation, long-term observations, analysis and subgroups separately
- Conditions for verification: Original allocation, extension eligibility, full cohort, subgroups and denominators; preserve only original values, direct observations, scope and gaps without creating new effects, verdicts, calculations or independence certification.
- Why this condition is needed: Production condition separating direct material and gaps for the selected time point, full cohort/subgroups and work outcome
- Application exceptions: Other time points, subgroups, questionnaires, services or denominators do not fill unresolved information in the selected material
- Remaining uncertainty: External abstracts, full texts, registration, protocol and SAP unread; no new calculations or clinical-content review performed
- Referenced methods: Linkage to preserved methodology-application records; full-definition content review and official certification incomplete
- Related sources: R01, R02

### N03 · Is the 10-to-46-month observation window the same as the original program duration?

Verification status: Partly verified  
Reading scope: Summary read; related external material unread

- Current findings: The long-term report covers an extension over 10 to 46 months. The original combined service included up to 15 CBT sessions and individual job support.
- Why unverified: Stored-summary information, scope and gaps displayed; not completed content review or a new clinical verdict
- Reason for missing information: Do not describe 10 to 46 months as continuous treatment or an exact interval since treatment ended. Individual exposure and follow-up-window details remain unverified.
- Required materials and conditions: Extension time points, duration, observation window, termination and exposure
- Materials to obtain first: Extension observation windows, original treatment duration and additional exposure data
- Further research: Distinguish treatment exposure from observation duration
- Conditions for verification: Extension time points, duration, observation window, termination and exposure; preserve only original values, direct observations, scope and gaps without creating new effects, verdicts, calculations or independence certification.
- Why this condition is needed: Production condition separating direct material and gaps for the selected time point, full cohort/subgroups and work outcome
- Application exceptions: Other time points, subgroups, questionnaires, services or denominators do not fill unresolved information in the selected material
- Remaining uncertainty: External abstracts, full texts, registration, protocol and SAP unread; no new calculations or clinical-content review performed
- Referenced methods: Linkage to preserved methodology-application records; full-definition content review and official certification incomplete
- Related sources: R01, R02

### N04 · Are the original combined service and usual care preserved accurately?

Verification status: Partly verified  
Reading scope: Summary read; related external material unread

- Current findings: The original allocation comparison was combined AWaC work-focused CBT and individual job support versus usual care.
- Why unverified: Stored-summary information, scope and gaps displayed; not completed content review or a new clinical verdict
- Reason for missing information: Do not convert this into CBT alone, job support alone or a no-treatment comparison. Long-term usual-care/additional-service details are unread; do not write treatment implementation instructions.
- Required materials and conditions: Specifications of CBT, job support, usual care and additional management
- Materials to obtain first: Original/additional services and arm-specific usual-care data
- Further research: Show the scope of combined-service assignment and subsequent exposure
- Conditions for verification: Specifications of CBT, job support, usual care and additional management; preserve only original values, direct observations, scope and gaps without creating new effects, verdicts, calculations or independence certification.
- Why this condition is needed: Production condition separating direct material and gaps for the selected time point, full cohort/subgroups and work outcome
- Application exceptions: Other time points, subgroups, questionnaires, services or denominators do not fill unresolved information in the selected material
- Remaining uncertainty: External abstracts, full texts, registration, protocol and SAP unread; no new calculations or clinical-content review performed
- Referenced methods: Linkage to preserved methodology-application records; full-definition content review and official certification incomplete
- Related sources: R01, R02

### N05 · Are long-term income, work participation and months without benefits separate outcomes?

Verification status: Partly verified  
Reading scope: Summary read; related external material unread

- Current findings: The preserved counterview states that full-cohort differences in income, work participation and months without benefits were not significant.
- Why unverified: Stored-summary information, scope and gaps displayed; not completed content review or a new clinical verdict
- Reason for missing information: Do not combine the three endpoints into one score or equate work, benefits and income. Detailed definitions, units and measurement windows are unread.
- Required materials and conditions: Definitions, units, aggregation and periods for each long-term endpoint
- Materials to obtain first: Long-term endpoint definitions, data and original result tables
- Further research: Present income, work and periods without benefits separately
- Conditions for verification: Definitions, units, aggregation and periods for each long-term endpoint; preserve only original values, direct observations, scope and gaps without creating new effects, verdicts, calculations or independence certification.
- Why this condition is needed: Production condition separating direct material and gaps for the selected time point, full cohort/subgroups and work outcome
- Application exceptions: Other time points, subgroups, questionnaires, services or denominators do not fill unresolved information in the selected material
- Remaining uncertainty: External abstracts, full texts, registration, protocol and SAP unread; no new calculations or clinical-content review performed
- Referenced methods: Linkage to preserved methodology-application records; full-definition content review and official certification incomplete
- Related sources: R02

### N06 · Are long-term full-cohort effect estimates, CIs and P values provided?

Verification status: Partly verified  
Reading scope: Summary read; related external material unread

- Current findings: The preserved long-term account provides qualitative information that full-cohort differences in the three outcomes were not significant.
- Why unverified: Stored-summary information, scope and gaps displayed; not completed content review or a new clinical verdict
- Reason for missing information: Exact long-term full-cohort effects, CIs and P values are absent from the summary. Do not copy the 12-month +6.2 percentage points or 18-month +7.8 percentage points as long-term estimates.
- Required materials and conditions: Endpoint-specific direct differences, ratios, intervals, tests and models
- Materials to obtain first: Original long-term endpoint effect, interval and P-value tables
- Further research: Distinguish the qualitative null account from gaps in direct numerical results
- Conditions for verification: Endpoint-specific direct differences, ratios, intervals, tests and models; preserve only original values, direct observations, scope and gaps without creating new effects, verdicts, calculations or independence certification.
- Why this condition is needed: Production condition separating direct material and gaps for the selected time point, full cohort/subgroups and work outcome
- Application exceptions: Other time points, subgroups, questionnaires, services or denominators do not fill unresolved information in the selected material
- Remaining uncertainty: External abstracts, full texts, registration, protocol and SAP unread; no new calculations or clinical-content review performed
- Referenced methods: Linkage to preserved methodology-application records; full-definition content review and official certification incomplete
- Related sources: R02

### N07 · Has a null long-term result been turned into exact zero, equivalence or exclusion of every benefit?

Verification status: Partly verified  
Reading scope: Summary read; related external material unread

- Current findings: The selected note and counterview record a null full-cohort result and unverified durable benefit.
- Why unverified: Stored-summary information, scope and gaps displayed; not completed content review or a new clinical verdict
- Reason for missing information: This does not certify an exactly zero effect, exclusion of all meaningful benefit or equivalence to the comparator. Prespecified long-term important-difference/equivalence criteria are also unverified.
- Required materials and conditions: Long-term question, intervals, comparison criteria and original interpretation
- Materials to obtain first: Original long-term analyses, importance and comparison criteria
- Further research: Distinguish a null finding from exclusion and equivalence
- Conditions for verification: Long-term question, intervals, comparison criteria and original interpretation; preserve only original values, direct observations, scope and gaps without creating new effects, verdicts, calculations or independence certification.
- Why this condition is needed: Production condition separating direct material and gaps for the selected time point, full cohort/subgroups and work outcome
- Application exceptions: Other time points, subgroups, questionnaires, services or denominators do not fill unresolved information in the selected material
- Remaining uncertainty: External abstracts, full texts, registration, protocol and SAP unread; no new calculations or clinical-content review performed
- Referenced methods: Linkage to preserved methodology-application records; full-definition content review and official certification incomplete
- Related sources: R02

### N08 · What are the definition and denominators of the long-term-benefit subgroup?

Verification status: Partly verified  
Reading scope: Summary read; related external material unread

- Current findings: The long-term report states that only the long-term-benefit subgroup had significant results.
- Why unverified: Stored-summary information, scope and gaps displayed; not completed content review or a new clinical verdict
- Reason for missing information: Benefit types, the long-term criterion, subgroup counts, arm denominators and effects/CIs/P values are unverified. Do not invent criteria or values.
- Required materials and conditions: Subgroup baseline status, duration, criteria, participants and denominators
- Materials to obtain first: Subgroup definitions, baseline data, denominators and original effect tables
- Further research: Distinguish direct evidence for the full cohort from evidence for the precisely defined subgroup
- Conditions for verification: Subgroup baseline status, duration, criteria, participants and denominators; preserve only original values, direct observations, scope and gaps without creating new effects, verdicts, calculations or independence certification.
- Why this condition is needed: Production condition separating direct material and gaps for the selected time point, full cohort/subgroups and work outcome
- Application exceptions: Other time points, subgroups, questionnaires, services or denominators do not fill unresolved information in the selected material
- Remaining uncertainty: External abstracts, full texts, registration, protocol and SAP unread; no new calculations or clinical-content review performed
- Referenced methods: Linkage to preserved methodology-application records; full-definition content review and official certification incomplete
- Related sources: R02

### N09 · Does within-subgroup significance prove a full-cohort effect or interaction?

Verification status: Partly verified  
Reading scope: Summary read; related external material unread

- Current findings: The original account describes a null full-cohort result and significance only in some long-term-benefit subgroup results.
- Why unverified: Stored-summary information, scope and gaps displayed; not completed content review or a new clinical verdict
- Reason for missing information: A subgroup signal does not establish full-cohort superiority or between-subgroup differences/interactions. Plans, tests and multiplicity are unread.
- Required materials and conditions: Prespecified subgroup plans, multiplicity, effect differences and interactions
- Materials to obtain first: Original subgroup plans, multiplicity and interaction data
- Further research: Distinguish within-subgroup results from direct between-group differences
- Conditions for verification: Prespecified subgroup plans, multiplicity, effect differences and interactions; preserve only original values, direct observations, scope and gaps without creating new effects, verdicts, calculations or independence certification.
- Why this condition is needed: Production condition separating direct material and gaps for the selected time point, full cohort/subgroups and work outcome
- Application exceptions: Other time points, subgroups, questionnaires, services or denominators do not fill unresolved information in the selected material
- Remaining uncertainty: External abstracts, full texts, registration, protocol and SAP unread; no new calculations or clinical-content review performed
- Referenced methods: Linkage to preserved methodology-application records; full-definition content review and official certification incomplete
- Related sources: R02

### N10 · Are 12-month maintenance/restoration and the long-term full-cohort results the same endpoint?

Verification status: Partly verified  
Reading scope: Summary read; related external material unread

- Current findings: At 12 months, maintenance/increase was 44.2% versus 37.2%, with an unadjusted 6.9-percentage-point difference (P=.015) and adjusted +6.2 percentage points (95% CI +0.5 to +11.8). The long-term account concerns income, work and months without benefits.
- Why unverified: Stored-summary information, scope and gaps displayed; not completed content review or a new clinical verdict
- Reason for missing information: Do not transfer short-term classifications, unadjusted/adjusted estimates or denominators to other long-term outcomes. Do not calculate sustained-maintenance or relapse/return-to-work rates.
- Required materials and conditions: Time-specific classifications, data, estimands and populations
- Materials to obtain first: Original time-specific work classifications, denominators and effect tables
- Further research: Separate direct short-term effects from estimates for each long-term endpoint
- Conditions for verification: Time-specific classifications, data, estimands and populations; preserve only original values, direct observations, scope and gaps without creating new effects, verdicts, calculations or independence certification.
- Why this condition is needed: Production condition separating direct material and gaps for the selected time point, full cohort/subgroups and work outcome
- Application exceptions: Other time points, subgroups, questionnaires, services or denominators do not fill unresolved information in the selected material
- Remaining uncertainty: External abstracts, full texts, registration, protocol and SAP unread; no new calculations or clinical-content review performed
- Referenced methods: Linkage to preserved methodology-application records; full-definition content review and official certification incomplete
- Related sources: R01, R02

### N11 · Does the observed 18-month difference confirm long-term full-cohort benefit?

Verification status: Partly verified  
Reading scope: Summary read; related external material unread

- Current findings: The original product-facts account records an observed +7.8-percentage-point difference at 18 months (P=.018) and explicitly leaves long-term full-cohort superiority unverified.
- Why unverified: Stored-summary information, scope and gaps displayed; not completed content review or a new clinical verdict
- Reason for missing information: The 18-month CI, denominators and adjustment details are absent. Do not promote a single-time-point difference to a whole-period long-term effect or independent replication.
- Required materials and conditions: 18-month observations and 10-to-46-month extension models and denominators
- Materials to obtain first: 18-month and long-term models, denominators and interval data
- Further research: Distinguish an observation time point from the scope of long-term analysis
- Conditions for verification: 18-month observations and 10-to-46-month extension models and denominators; preserve only original values, direct observations, scope and gaps without creating new effects, verdicts, calculations or independence certification.
- Why this condition is needed: Production condition separating direct material and gaps for the selected time point, full cohort/subgroups and work outcome
- Application exceptions: Other time points, subgroups, questionnaires, services or denominators do not fill unresolved information in the selected material
- Remaining uncertainty: External abstracts, full texts, registration, protocol and SAP unread; no new calculations or clinical-content review performed
- Referenced methods: Linkage to preserved methodology-application records; full-definition content review and official certification incomplete
- Related sources: R01, R02

### N12 · Has zero 12-month follow-up loss been reused as complete long-term follow-up?

Verification status: Partly verified  
Reading scope: Summary read; related external material unread

- Current findings: Complete register outcomes for 1,193 participants and loss of 0/1,193 are original information about the 12-month primary outcome.
- Why unverified: Stored-summary information, scope and gaps displayed; not completed content review or a new clinical verdict
- Reason for missing information: Sharing a cohort does not certify zero data loss for every long-term endpoint and period. Long-term denominator details are unread.
- Required materials and conditions: Long-term register linkage, observation, losses and endpoint-specific denominators
- Materials to obtain first: Long-term endpoint observations, register linkage and analysis denominators
- Further research: Present the actual scope of complete follow-up at each time point separately
- Conditions for verification: Long-term register linkage, observation, losses and endpoint-specific denominators; preserve only original values, direct observations, scope and gaps without creating new effects, verdicts, calculations or independence certification.
- Why this condition is needed: Production condition separating direct material and gaps for the selected time point, full cohort/subgroups and work outcome
- Application exceptions: Other time points, subgroups, questionnaires, services or denominators do not fill unresolved information in the selected material
- Remaining uncertainty: External abstracts, full texts, registration, protocol and SAP unread; no new calculations or clinical-content review performed
- Referenced methods: Linkage to preserved methodology-application records; full-definition content review and official certification incomplete
- Related sources: R02

### N13 · Are long-term register data and handling of missingness, movement and benefit status known?

Verification status: Unverified  
Reading scope: Summary read; related external material unread

- Current findings: The parent rationale describes monthly work and benefit status ascertained through national social-insurance and employment registers.
- Why unverified: Stored-summary information, scope and gaps displayed; not completed content review or a new clinical verdict
- Reason for missing information: Long-term missingness, movement, data errors, benefit-classification changes and processing methods are absent from the summary. Objective data do not establish absence of every error.
- Required materials and conditions: Register definitions, linkage, missingness, status changes and measurement error
- Materials to obtain first: Original long-term register-processing, error and missingness specifications
- Further research: Distinguish objective ascertainment from actual processing limitations
- Conditions for verification: Register definitions, linkage, missingness, status changes and measurement error; preserve only original values, direct observations, scope and gaps without creating new effects, verdicts, calculations or independence certification.
- Why this condition is needed: Production condition separating direct material and gaps for the selected time point, full cohort/subgroups and work outcome
- Application exceptions: Other time points, subgroups, questionnaires, services or denominators do not fill unresolved information in the selected material
- Remaining uncertainty: External abstracts, full texts, registration, protocol and SAP unread; no new calculations or clinical-content review performed
- Referenced methods: Linkage to preserved methodology-application records; full-definition content review and official certification incomplete
- Related sources: R02

### N14 · Are long-term estimands, covariates and statistical models verified?

Verification status: Unverified  
Reading scope: Summary read; related external material unread

- Current findings: Information that the long-term full-cohort result was not significant coexists with the original prespecified adjusted 12-month effect.
- Why unverified: Stored-summary information, scope and gaps displayed; not completed content review or a new clinical verdict
- Reason for missing information: Do not automatically apply 12-month models/prespecified covariates to the long-term analysis or label it an effect of all observations or actual participation. Long-term model details are unread.
- Required materials and conditions: Long-term analysis populations, models, adjustment, repeated data and periods
- Materials to obtain first: Long-term models, covariates, repeated-data handling and analysis populations
- Further research: Distinguish short-term and long-term estimands and models
- Conditions for verification: Long-term analysis populations, models, adjustment, repeated data and periods; preserve only original values, direct observations, scope and gaps without creating new effects, verdicts, calculations or independence certification.
- Why this condition is needed: Production condition separating direct material and gaps for the selected time point, full cohort/subgroups and work outcome
- Application exceptions: Other time points, subgroups, questionnaires, services or denominators do not fill unresolved information in the selected material
- Remaining uncertainty: External abstracts, full texts, registration, protocol and SAP unread; no new calculations or clinical-content review performed
- Referenced methods: Linkage to preserved methodology-application records; full-definition content review and official certification incomplete
- Related sources: R02

### N15 · Are original allocation implementation and long-term selection/cross-exposure distinguished?

Verification status: Partly verified  
Reading scope: Summary read; related external material unread

- Current findings: The original trial is described as a six-center pragmatic randomized trial with independent allocation, unmasked participants and register-based outcome ascertainment.
- Why unverified: Stored-summary information, scope and gaps displayed; not completed content review or a new clinical verdict
- Reason for missing information: Do not make the extension a new randomized trial. Details of follow-up selection, additional services, arm changes and concomitant exposure remain unverified.
- Required materials and conditions: Allocation, follow-up selection, additional services, concomitant treatment and arm changes
- Materials to obtain first: Original long-term participation, exposure changes, services and register data
- Further research: Distinguish original allocation from limitations of actual long-term exposure/observation
- Conditions for verification: Allocation, follow-up selection, additional services, concomitant treatment and arm changes; preserve only original values, direct observations, scope and gaps without creating new effects, verdicts, calculations or independence certification.
- Why this condition is needed: Production condition separating direct material and gaps for the selected time point, full cohort/subgroups and work outcome
- Application exceptions: Other time points, subgroups, questionnaires, services or denominators do not fill unresolved information in the selected material
- Remaining uncertainty: External abstracts, full texts, registration, protocol and SAP unread; no new calculations or clinical-content review performed
- Referenced methods: Linkage to preserved methodology-application records; full-definition content review and official certification incomplete
- Related sources: R01, R02

### N16 · Has the 5% treatment-participation figure been combined with long-term work denominators?

Verification status: Partly verified  
Reading scope: Summary read; related external material unread

- Current findings: The original safety account describes 5% as stopping treatment/attending fewer than 3 AWaC sessions.
- Why unverified: Stored-summary information, scope and gaps displayed; not completed content review or a new clinical verdict
- Reason for missing information: Do not convert 5% to long-term loss, harm incidence or a denominator for all work outcomes, or calculate counts using the randomized total. Long-term participation/exposure denominators are separate.
- Required materials and conditions: Attendance, stopping, reasons, timing and long-term register observation
- Materials to obtain first: Treatment attendance/stopping and long-term data flow
- Further research: Distinguish service participation from register-outcome follow-up
- Conditions for verification: Attendance, stopping, reasons, timing and long-term register observation; preserve only original values, direct observations, scope and gaps without creating new effects, verdicts, calculations or independence certification.
- Why this condition is needed: Production condition separating direct material and gaps for the selected time point, full cohort/subgroups and work outcome
- Application exceptions: Other time points, subgroups, questionnaires, services or denominators do not fill unresolved information in the selected material
- Remaining uncertainty: External abstracts, full texts, registration, protocol and SAP unread; no new calculations or clinical-content review performed
- Referenced methods: Linkage to preserved methodology-application records; full-definition content review and official certification incomplete
- Related sources: R01, R02

### N17 · Are long-term full-cohort/subgroup plans distinct from the original primary-outcome plan?

Verification status: Partly verified  
Reading scope: Summary read; related external material unread

- Current findings: The original primary outcome is objective work participation at 12 months, described as matching NCT01146730. The long-term report is an extension of the same trial.
- Why unverified: Stored-summary information, scope and gaps displayed; not completed content review or a new clinical verdict
- Reason for missing information: Do not reuse original primary-outcome prespecification as certification of long-term endpoints or subgroup plans. Long-term plans, changes and multiplicity remain externally unread.
- Required materials and conditions: Protocol, SAP, registration history, long-term endpoints and hierarchy
- Materials to obtain first: Registration, long-term plans, SAP and amendment documents
- Further research: Separate original primary-outcome plans from long-term and subgroup plans
- Conditions for verification: Protocol, SAP, registration history, long-term endpoints and hierarchy; preserve only original values, direct observations, scope and gaps without creating new effects, verdicts, calculations or independence certification.
- Why this condition is needed: Production condition separating direct material and gaps for the selected time point, full cohort/subgroups and work outcome
- Application exceptions: Other time points, subgroups, questionnaires, services or denominators do not fill unresolved information in the selected material
- Remaining uncertainty: External abstracts, full texts, registration, protocol and SAP unread; no new calculations or clinical-content review performed
- Referenced methods: Linkage to preserved methodology-application records; full-definition content review and official certification incomplete
- Related sources: R01, R02, R03

### N18 · Have long-term importance, clinical function and economic results been invented?

Verification status: Partly verified  
Reading scope: Summary read; related external material unread

- Current findings: The follow-up citation concerns long-term income and sickness benefits; the preserved account records null full-cohort results for three outcomes.
- Why unverified: Stored-summary information, scope and gaps displayed; not completed content review or a new clinical verdict
- Reason for missing information: Do not create new effects, economic costs, quality-of-life outcomes, symptom remission, individual examples or clinical minimum thresholds. Direct data for each outcome are separately needed.
- Required materials and conditions: Definitions and importance of income, work and months without benefits, and other outcomes
- Materials to obtain first: Original long-term work, economic and clinical-function results
- Further research: Distinguish direct long-term endpoints from gaps in other outcomes and importance
- Conditions for verification: Definitions and importance of income, work and months without benefits, and other outcomes; preserve only original values, direct observations, scope and gaps without creating new effects, verdicts, calculations or independence certification.
- Why this condition is needed: Production condition separating direct material and gaps for the selected time point, full cohort/subgroups and work outcome
- Application exceptions: Other time points, subgroups, questionnaires, services or denominators do not fill unresolved information in the selected material
- Remaining uncertainty: External abstracts, full texts, registration, protocol and SAP unread; no new calculations or clinical-content review performed
- Referenced methods: Linkage to preserved methodology-application records; full-definition content review and official certification incomplete
- Related sources: R02

### N19 · Are three same-cohort citations, registration and sibling sheets independent replication?

Verification status: Partly verified  
Reading scope: Summary read; related external material unread

- Current findings: The original evidence describes AWaC and the same-trial long-term report; the 3 citations comprise the original report, long-term report and registration.
- Why unverified: Stored-summary information, scope and gaps displayed; not completed content review or a new clinical verdict
- Reason for missing information: Do not sum 3 reports, sibling sheets, monthly data, centers or arms as new independent trials or participants. Confirmed trial/participant counts are unrecorded.
- Required materials and conditions: Links among original/long-term reports, registration, participants and repeated data
- Materials to obtain first: Original/long-term report, registration and participant-linkage data
- Further research: Distinguish report slots from actual trial and participant units
- Conditions for verification: Links among original/long-term reports, registration, participants and repeated data; preserve only original values, direct observations, scope and gaps without creating new effects, verdicts, calculations or independence certification.
- Why this condition is needed: Production condition separating direct material and gaps for the selected time point, full cohort/subgroups and work outcome
- Application exceptions: Other time points, subgroups, questionnaires, services or denominators do not fill unresolved information in the selected material
- Remaining uncertainty: External abstracts, full texts, registration, protocol and SAP unread; no new calculations or clinical-content review performed
- Referenced methods: Linkage to preserved methodology-application records; full-definition content review and official certification incomplete
- Related sources: R01, R02, R03

### N20 · Has the result been extended to other services, populations or countries?

Verification status: Partly verified  
Reading scope: Summary read; related external material unread

- Current findings: The evidence concerns the combined Norwegian AWaC service. The preserved summary describes different delivery systems and populations for verdict 2944 on physiotherapist vocational advice.
- Why unverified: Stored-summary information, scope and gaps displayed; not completed content review or a new clinical verdict
- Reason for missing information: Related verdicts/links have not been newly read or checked. Do not turn the long-term null result into a null result for every CBT, job-support or vocational-advice service.
- Required materials and conditions: Direct data for each combined service, delivery system, population and institutional setting
- Materials to obtain first: Direct comparative data for services, institutions and populations
- Further research: Distinguish original related context from the selected long-term full-cohort question
- Conditions for verification: Direct data for each combined service, delivery system, population and institutional setting; preserve only original values, direct observations, scope and gaps without creating new effects, verdicts, calculations or independence certification.
- Why this condition is needed: Production condition separating direct material and gaps for the selected time point, full cohort/subgroups and work outcome
- Application exceptions: Other time points, subgroups, questionnaires, services or denominators do not fill unresolved information in the selected material
- Remaining uncertainty: External abstracts, full texts, registration, protocol and SAP unread; no new calculations or clinical-content review performed
- Referenced methods: Linkage to preserved methodology-application records; full-definition content review and official certification incomplete
- Related sources: R01, R02

### N21 · Have long-term effects in excluded severe or high-risk populations been filled in?

Verification status: Partly verified  
Reading scope: Summary read; related external material unread

- Current findings: The original material states that high suicide risk, severe mental illness and active substance use were excluded.
- Why unverified: Stored-summary information, scope and gaps displayed; not completed content review or a new clinical verdict
- Reason for missing information: Do not certify long-term effects, safety or treatment suitability in excluded populations. Do not equate the long-term-benefit subgroup with a severe-mental-illness population.
- Required materials and conditions: Baseline risk, diagnosis, exclusions and long-term-subgroup eligibility
- Materials to obtain first: Original baseline, exclusion and long-term-subgroup eligibility data
- Further research: Distinguish long-term economic/benefit subgroups from populations defined by clinical risk
- Conditions for verification: Baseline risk, diagnosis, exclusions and long-term-subgroup eligibility; preserve only original values, direct observations, scope and gaps without creating new effects, verdicts, calculations or independence certification.
- Why this condition is needed: Production condition separating direct material and gaps for the selected time point, full cohort/subgroups and work outcome
- Application exceptions: Other time points, subgroups, questionnaires, services or denominators do not fill unresolved information in the selected material
- Remaining uncertainty: External abstracts, full texts, registration, protocol and SAP unread; no new calculations or clinical-content review performed
- Referenced methods: Linkage to preserved methodology-application records; full-definition content review and official certification incomplete
- Related sources: R02

### N22 · Are public funding, NAV operation and independent evaluation distinguished for long-term roles?

Verification status: Partly verified  
Reading scope: Summary read; related external material unread

- Current findings: The original summary describes full funding by the Ministries of Health and Labour, NAV center operation and an evaluation team uninvolved in center operation or treatment.
- Why unverified: Stored-summary information, scope and gaps displayed; not completed content review or a new clinical verdict
- Reason for missing information: Do not convert the original evaluation role into new certification of independence for every long-term analysis, data process or publication. Separate long-term disclosures are unread.
- Required materials and conditions: Original/long-term funding, operation, evaluation and data-control disclosures
- Materials to obtain first: Original/long-term funding, operation, evaluation and authority disclosures
- Further research: Record original support and long-term analytical roles separately
- Conditions for verification: Original/long-term funding, operation, evaluation and data-control disclosures; preserve only original values, direct observations, scope and gaps without creating new effects, verdicts, calculations or independence certification.
- Why this condition is needed: Production condition separating direct material and gaps for the selected time point, full cohort/subgroups and work outcome
- Application exceptions: Other time points, subgroups, questionnaires, services or denominators do not fill unresolved information in the selected material
- Remaining uncertainty: External abstracts, full texts, registration, protocol and SAP unread; no new calculations or clinical-content review performed
- Referenced methods: Linkage to preserved methodology-application records; full-definition content review and official certification incomplete
- Related sources: R01, R02

### N23 · Have long-term authorship, analysis, writing, publication and company involvement been verified?

Verification status: Unverified  
Reading scope: Summary read; related external material unread

- Current findings: The current preserved summary provides original public funding, operation/evaluation information and the long-term citation.
- Why unverified: Stored-summary information, scope and gaps displayed; not completed content review or a new clinical verdict
- Reason for missing information: Do not certify that unmentioned long-term author relationships, outsourced analysis, medical writing, publication fees or other company involvement are all absent.
- Required materials and conditions: Long-term disclosures, author relationships, analysis, writing, publication and data control
- Materials to obtain first: Long-term disclosures, contributions and data/publication authority
- Further research: Distinguish reported support from unverified long-term roles
- Conditions for verification: Long-term disclosures, author relationships, analysis, writing, publication and data control; preserve only original values, direct observations, scope and gaps without creating new effects, verdicts, calculations or independence certification.
- Why this condition is needed: Production condition separating direct material and gaps for the selected time point, full cohort/subgroups and work outcome
- Application exceptions: Other time points, subgroups, questionnaires, services or denominators do not fill unresolved information in the selected material
- Remaining uncertainty: External abstracts, full texts, registration, protocol and SAP unread; no new calculations or clinical-content review performed
- Referenced methods: Linkage to preserved methodology-application records; full-definition content review and official certification incomplete
- Related sources: R02

### N24 · Are long-term work data equivalent to collection of clinical safety outcomes?

Verification status: Partly verified  
Reading scope: Summary read; related external material unread

- Current findings: The parent safety account states that prespecified safety endpoints and a serious-event comparison table were absent, leaving safety unknown.
- Why unverified: Stored-summary information, scope and gaps displayed; not completed content review or a new clinical verdict
- Reason for missing information: Having long-term work registers does not establish complete clinical-harm collection, no events or equivalence to the comparator.
- Required materials and conditions: Prespecified harms, event collection, arm denominators and clinical follow-up
- Materials to obtain first: Long-term arm-specific harms, collection and exposure data
- Further research: Separate long-term work endpoints from clinical safety data
- Conditions for verification: Prespecified harms, event collection, arm denominators and clinical follow-up; preserve only original values, direct observations, scope and gaps without creating new effects, verdicts, calculations or independence certification.
- Why this condition is needed: Supplementary condition revealing harm collection, exposure and population scope separately from efficacy
- Application exceptions: Other time points, subgroups, questionnaires, services or denominators do not fill unresolved information in the selected material
- Remaining uncertainty: External abstracts, full texts, registration, protocol and SAP unread; no new calculations or clinical-content review performed
- Referenced methods: Linkage to preserved methodology-application records; full-definition content review and official certification incomplete
- Related sources: R01, R02

### N25 · Are long-term/rare harms and reasons for stopping separately verified?

Verification status: Unverified  
Reading scope: Summary read; related external material unread

- Current findings: The original 5% attending fewer than 3 sessions and exclusion of high-risk participants provide limited information.
- Why unverified: Stored-summary information, scope and gaps displayed; not completed content review or a new clinical verdict
- Reason for missing information: Do not automatically classify stopping as harm or efficacy failure, or infer absence of long-term/rare harms. Do not create treatment implementation/change guidance.
- Required materials and conditions: Long-term exposure, events, stopping, other causes and rare outcomes
- Materials to obtain first: Long-term stopping, reasons, events and exposure follow-up
- Further research: Distinguish participation/stopping from gaps in direct harm and causation
- Conditions for verification: Long-term exposure, events, stopping, other causes and rare outcomes; preserve only original values, direct observations, scope and gaps without creating new effects, verdicts, calculations or independence certification.
- Why this condition is needed: Supplementary condition revealing harm collection, exposure and population scope separately from efficacy
- Application exceptions: Other time points, subgroups, questionnaires, services or denominators do not fill unresolved information in the selected material
- Remaining uncertainty: External abstracts, full texts, registration, protocol and SAP unread; no new calculations or clinical-content review performed
- Referenced methods: Linkage to preserved methodology-application records; full-definition content review and official certification incomplete
- Related sources: R02

### N26 · Were actual long-term reports and registration documents read?

Verification status: Partly verified  
Reading scope: Summary read; related external material unread

- Current findings: The material read was the whole parent summary. Original/long-term PubMed and official NCT URLs are linked as originally cited.
- Why unverified: Stored-summary information, scope and gaps displayed; not completed content review or a new clinical verdict
- Reason for missing information: External abstracts, full texts, registration, protocol and SAP were not read; links/screens were not checked clinically. URL presence does not establish external reading or clinical QA.
- Required materials and conditions: Citations, original URLs, preserved summary and abstract/full-text/registration/plan status
- Materials to obtain first: Original/long-term reports, registration and plan materials
- Further research: Show summary reading separately from each category of externally unread material
- Conditions for verification: Citations, original URLs, preserved summary and abstract/full-text/registration/plan status; preserve only original values, direct observations, scope and gaps without creating new effects, verdicts, calculations or independence certification.
- Why this condition is needed: Production condition separating direct material and gaps for the selected time point, full cohort/subgroups and work outcome
- Application exceptions: Other time points, subgroups, questionnaires, services or denominators do not fill unresolved information in the selected material
- Remaining uncertainty: External abstracts, full texts, registration, protocol and SAP unread; no new calculations or clinical-content review performed
- Referenced methods: Linkage to preserved methodology-application records; full-definition content review and official certification incomplete
- Related sources: R01, R02, R03

### N27 · Are the long-term subclaim and parent Korean/English text, axes, dates and corrections distinguished?

Verification status: Partly verified  
Reading scope: Summary read; related external material unread

- Current findings: The whole preserved summary retains Korean/English text, axes, the 2026-08-26 evidence date, empty corrections/deliberation and the long-term row.
- Why unverified: Stored-summary information, scope and gaps displayed; not completed content review or a new clinical verdict
- Reason for missing information: Do not fill the long-term row’s missing score, status or axes with parent B and 76 points. Do not replace the original evidence date with the current review date.
- Required materials and conditions: Whole parent original, long-term row, evidence date and corrections
- Materials to obtain first: Original preserved summary and subclaim/parent history
- Further research: Distinguish original verdict/corrections from the selected long-term context
- Conditions for verification: Whole parent original, long-term row, evidence date and corrections; preserve only original values, direct observations, scope and gaps without creating new effects, verdicts, calculations or independence certification.
- Why this condition is needed: Production condition separating direct material and gaps for the selected time point, full cohort/subgroups and work outcome
- Application exceptions: Other time points, subgroups, questionnaires, services or denominators do not fill unresolved information in the selected material
- Remaining uncertainty: External abstracts, full texts, registration, protocol and SAP unread; no new calculations or clinical-content review performed
- Referenced methods: Linkage to preserved methodology-application records; full-definition content review and official certification incomplete
- Related sources: R01, R02, R03

### N28 · Are the existing candidate, freezing/application and human review separated?

Verification status: Partly verified  
Reading scope: Summary read; related external material unread

- Current findings: Only the existing selected unit is produced; claim and record references are distinguished. Candidate pending/eligible values are original history.
- Why unverified: Stored-summary information, scope and gaps displayed; not completed content review or a new clinical verdict
- Reason for missing information: Do not activate a review wait. Preserve incomplete original review, false completion flags, 0 new units and unrecorded final independent counts. Do not create new effects, verdicts or treatment instructions.
- Required materials and conditions: Claim/record references, original candidate state and production events
- Materials to obtain first: Existing selection and condition-freezing/application events
- Further research: Distinguish saved production from human content review and clinical certification
- Conditions for verification: Claim/record references, original candidate state and production events; preserve only original values, direct observations, scope and gaps without creating new effects, verdicts, calculations or independence certification.
- Why this condition is needed: Production condition separating direct material and gaps for the selected time point, full cohort/subgroups and work outcome
- Application exceptions: Other time points, subgroups, questionnaires, services or denominators do not fill unresolved information in the selected material
- Remaining uncertainty: External abstracts, full texts, registration, protocol and SAP unread; no new calculations or clinical-content review performed
- Referenced methods: Linkage to preserved methodology-application records; full-definition content review and official certification incomplete
- Related sources: R01, R02, R03

## Evidence and sources

### R01

Reme SE, et al. Occup Environ Med. 2015. PMID: 26251065.

[PubMed](https://pubmed.ncbi.nlm.nih.gov/26251065/)

Materials actually read: Summary read; external abstracts, full texts, registration and plans unread  
Findings recorded in the summary: The grade is B with 76 points. In AWaC, maintained/increased work participation at 12 months was 44.2% versus 37.2%, unadjusted difference 6.9 percentage points (P=.015), and prespecified covariate-adjusted marginal effect +6.2 percentage points (95% CI +0.5~+11.8).  
Record level: AWaC objective 12-month work participation; original proportions/unadjusted/adjusted effects and complete register follow-up for the primary outcome  
Independent replication: Main/long-term AWaC reports and registration linked by the original stored summary; three citations, repeated monthly records, arms and sibling sheets are not totaled as new trials/participants

| Material | Public availability | Access status | Actually read | Notes |
|---|---|---|---|---|
| Stored summary | Summary read | Stored summary read | Summary read | Material entries do not establish external acquisition, reading, checked links or unique-trial/participant certification; the official registration URL is linked only to its registration entry |
| External abstract | Not read | External material unread | Not read | Material entries do not establish external acquisition, reading, checked links or unique-trial/participant certification; the official registration URL is linked only to its registration entry |
| External full text | Not read | External material unread | Not read | Material entries do not establish external acquisition, reading, checked links or unique-trial/participant certification; the official registration URL is linked only to its registration entry |
| Original registration | Not read | External material unread | Not read | Material entries do not establish external acquisition, reading, checked links or unique-trial/participant certification; the official registration URL is linked only to its registration entry |
| Protocol/SAP | Not read | External material unread | Not read | Material entries do not establish external acquisition, reading, checked links or unique-trial/participant certification; the official registration URL is linked only to its registration entry |

### R02

Long-term effects on income and sickness benefits after work-focused CBT and individual job support. PMID: 30032103.

[PubMed](https://pubmed.ncbi.nlm.nih.gov/30032103/)

Materials actually read: Summary read; external abstracts, full texts, registration and plans unread  
Findings recorded in the summary: The same-cohort 10~46-month extension found no significant full-cohort differences in income, work participation or months without benefits; only the long-term-benefit subgroup was significant. The established result concerns the full cohort at 12 months, not persistence of effect.  
Record level: Same AWaC 10~46-month extension: null full-cohort results and long-term-benefit subgroup context; long-term denominators/original values unverified  
Independent replication: Main/long-term AWaC reports and registration linked by the original stored summary; three citations, repeated monthly records, arms and sibling sheets are not totaled as new trials/participants

| Material | Public availability | Access status | Actually read | Notes |
|---|---|---|---|---|
| Stored summary | Summary read | Stored summary read | Summary read | Material entries do not establish external acquisition, reading, checked links or unique-trial/participant certification; the official registration URL is linked only to its registration entry |
| External abstract | Not read | External material unread | Not read | Material entries do not establish external acquisition, reading, checked links or unique-trial/participant certification; the official registration URL is linked only to its registration entry |
| External full text | Not read | External material unread | Not read | Material entries do not establish external acquisition, reading, checked links or unique-trial/participant certification; the official registration URL is linked only to its registration entry |
| Original registration | Not read | External material unread | Not read | Material entries do not establish external acquisition, reading, checked links or unique-trial/participant certification; the official registration URL is linked only to its registration entry |
| Protocol/SAP | Not read | External material unread | Not read | Material entries do not establish external acquisition, reading, checked links or unique-trial/participant certification; the official registration URL is linked only to its registration entry |

### R03

NCT01146730. At Work and Coping.

[Official source](https://clinicaltrials.gov/study/NCT01146730)

Materials actually read: Summary read; external abstracts, full texts, registration and plans unread  
Findings recorded in the summary: Trial registration material.  
Record level: Same AWaC registration citation; original planning text unread, not a new clinical results report  
Independent replication: Main/long-term AWaC reports and registration linked by the original stored summary; three citations, repeated monthly records, arms and sibling sheets are not totaled as new trials/participants

| Material | Public availability | Access status | Actually read | Notes |
|---|---|---|---|---|
| Stored summary | Summary read | Stored summary read | Summary read | Material entries do not establish external acquisition, reading, checked links or unique-trial/participant certification; the official registration URL is linked only to its registration entry |
| External abstract | Not read | External material unread | Not read | Material entries do not establish external acquisition, reading, checked links or unique-trial/participant certification; the official registration URL is linked only to its registration entry |
| External full text | Not read | External material unread | Not read | Material entries do not establish external acquisition, reading, checked links or unique-trial/participant certification; the official registration URL is linked only to its registration entry |
| Original registration | Not read | External material unread | Not read | Material entries do not establish external acquisition, reading, checked links or unique-trial/participant certification; the official registration URL is linked only to its registration entry |
| Protocol/SAP | Not read | External material unread | Not read | Material entries do not establish external acquisition, reading, checked links or unique-trial/participant certification; the official registration URL is linked only to its registration entry |

## Review criteria and methods

These are Chamgap's own application conditions, informed by the relevant sections of official methodological guidance. They do not constitute official assessment-tool certification or a new efficacy score.

- M03 [Cochrane Handbook 6.5 (2024), chapter updated 2023-08](https://www.cochrane.org/authors/handbooks-and-manuals/handbook/current/chapter-03) · §3.1, §3.2.1–3.2.3, MECIR C5/C7/C13 · Clearly record the question, eligibility conditions and reasons for changes, and distinguish variations in interventions. · Preserved methodological linkages reused for production; no current methodological reassessment or external link checks, and historical quality review is not inherited
- M04 [Cochrane Handbook 6.5.1 (2025), chapter updated 2025-03](https://www.cochrane.org/authors/handbooks-and-manuals/handbook/current/chapter-04) · §4.5, §4.6.1–4.6.3, MECIR C42 · Distinguish studies from reports and link them; do not omit a study solely because results are unreported. · Preserved methodological linkages reused for production; no current methodological reassessment or external link checks, and historical quality review is not inherited
- M08 [Cochrane Handbook 6.5 (2024), chapter updated 2019-10](https://www.cochrane.org/authors/handbooks-and-manuals/handbook/current/chapter-08) · §8.1–8.2.3, Table 8.2.a · Define the outcome and effect of interest, then examine randomization, deviations, missing data, measurement and selective reporting. · Preserved methodological linkages reused for production; no current methodological reassessment or external link checks, and historical quality review is not inherited
- M15 [Cochrane Handbook 6.5 (2024), chapter updated 2023-08](https://www.cochrane.org/authors/handbooks-and-manuals/handbook/current/chapter-15) · §15.2.4, §15.3.1–15.3.3 · Distinguish effect estimates, intervals, importance and applicability. Sample size alone does not determine precision. · Preserved methodological linkages reused for production; no current methodological reassessment or external link checks, and historical quality review is not inherited
- M19 [Cochrane Handbook 6.5 (2024), chapter updated 2019-10](https://www.cochrane.org/authors/handbooks-and-manuals/handbook/current/chapter-19) · §19.1.2, §19.2.1–19.2.4 · Harm questions may require different designs, populations and follow-up from efficacy questions. Case reports do not establish incidence rates. · Preserved methodological linkages reused for production; no current methodological reassessment or external link checks, and historical quality review is not inherited

## What the statuses mean

- Partly verified: Some information exists in the preserved review summary; detailed original materials remain unverified. This does not certify a passed review or clinical efficacy.
- Unverified: Detailed materials for the selected condition could not be established within the stored scope; this does not mean zero effect, zero studies or safety
- Review incomplete: Review of existing content incomplete
- Met: Use only within the relevant conditions after existing content review; no automatic designation in this preparation
- Not reported: Distinguish only within materials actually read; do not turn unread external materials into unreported findings
- Inaccessible: Not applied during this preparation because actual access was not tested
- Not applicable: Use with a reason for non-applicability based on an explicit question boundary
- Conflicting data: Judge after actual material comparison; review was not performed during this preparation
- Insufficient evidence for the conditions: Do not use as a clinical grade encompassing currently unread materials

## Change history

2026-10-12 · Public page/materials 1.0. Public reader pages and material were prepared from the existing 28 items. No new clinical searches, verification-state changes or scoring were performed.