{ "schema_version": "chamgap-public-evidence-check-1.0", "public_id": "v2954-s1", "verdict_number": "2954", "title": "Work-focused CBT and job support × Durable benefit in the full cohort — Evidence Check", "view_version": "1.0", "view_created_date": "2026-10-12", "criteria_version": "1.0", "criteria_date": "2026-10-06", "review_date": null, "legacy_evidence_date": "2026-08-26", "review_scope": { "materials_read": "Existing review summaries and stored records of methodological application", "clinical_papers_directly_read": false, "new_clinical_search": false, "limitation": "The whole stored parent-verdict summary and selected subclaim were read for production. External papers, abstracts, full texts, registry, protocol, SAP and funding disclosures were not separately read or accessed. Historical review records are not inherited as current clinical verification or a new verdict.", "date_meaning": "This is the date the stored materials were checked, not the date of a new search of the clinical literature." }, "claim_context": { "population": "1,193 adults with anxiety/depression randomized at six Norwegian centers (630/563); high suicide risk, severe mental illness and active substance use excluded; exact long-term denominators separately unverified", "intervention": "Combined AWaC service with up to 15 sessions of work-focused CBT and individual job support", "dose": "Original study-service exposure context, not treatment/job-support implementation instructions; actual participation and subsequent exposure details unverified", "comparator": "Usual care; details of concomitant/additional treatments and arm-specific changes unread", "endpoint": "Full-cohort income, work participation and months without benefits over 10 to 46 months; separate from the long-term-benefit subgroup", "duration": "Separate the original 12-month primary outcome, 18-month observations and 10-to-46-month extension results", "excluded_extensions": [ "No new evidence, effects, CIs, calculations, verdicts, independence certification, participant totals, psychological treatment/job-support/drug changes or treatment instructions are created" ] }, "requirements": [ { "item_id": "N01", "question_type": "Comparative efficacy, work participation and time points", "question": "What are the original long-term full-cohort claim and subclaim verdict?", "needed": "Long-term full-cohort question, grade, note and parent context", "role": "Required", "role_reason": "Production condition separating direct material and gaps for the selected time point, full cohort/subgroups and work outcome", "application_exception": "Other time points, subgroups, questionnaires, services or denominators do not fill unresolved information in the selected material", "criterion": "Long-term full-cohort question, grade, note and parent context; preserve only original values, direct observations, scope and gaps without creating new effects, verdicts, calculations or independence certification.", "basis": "Linkage to preserved methodology-application records; full-definition content review and official certification incomplete", "condition_origin": "Chamgap-specific application condition; review of existing content incomplete", "proposed_research": "Distinguish the original long-term verdict from the 12-month context", "current_reports": [ "R02" ], "existence": "Related original wording, citations and context appear in the preserved existing summary; detailed external material is unverified", "acquired_read": "Summary read; related external material unread", "observation": "The selected row concerns the long-term full-cohort effect, carries original grade D and notes a null full-cohort extension over 10 to 46 months. The parent concerns 12 months, grade B with 76 points.", "condition_status": "Partly verified", "status_reason": "Stored-summary information, scope and gaps displayed; not completed content review or a new clinical verdict", "missingness": "The selected row has no score, status or axes. Do not fill these with the parent B, 76 points or E+, or treat them as long-term effects.", "uncertainty": "External abstracts, full texts, registration, protocol and SAP unread; no new calculations or clinical-content review performed", "review_date": null, "reading_status": "Full text not read · Stored summary read", "additional_material": "Selected row and original parent verdict" }, { "item_id": "N02", "question_type": "Comparative efficacy, work participation and time points", "question": "Which recruitment and analysis populations does the long-term full cohort refer to?", "needed": "Original allocation, extension eligibility, full cohort, subgroups and denominators", "role": "Required", "role_reason": "Production condition separating direct material and gaps for the selected time point, full cohort/subgroups and work outcome", "application_exception": "Other time points, subgroups, questionnaires, services or denominators do not fill unresolved information in the selected material", "criterion": "Original allocation, extension eligibility, full cohort, subgroups and denominators; preserve only original values, direct observations, scope and gaps without creating new effects, verdicts, calculations or independence certification.", "basis": "Linkage to preserved methodology-application records; full-definition content review and official certification incomplete", "condition_origin": "Chamgap-specific application condition; review of existing content incomplete", "proposed_research": "Present original allocation, long-term observations, analysis and subgroups separately", "current_reports": [ "R01", "R02" ], "existence": "Related original wording, citations and context appear in the preserved existing summary; detailed external material is unverified", "acquired_read": "Summary read; related external material unread", "observation": "The original trial randomized 1,193 adults with anxiety/depression (630/563); the extension analyzes the same cohort.", "condition_status": "Partly verified", "status_reason": "Stored-summary information, scope and gaps displayed; not completed content review or a new clinical verdict", "missingness": "Exact long-term analysis/follow-up denominators and eligibility details are absent from the summary. Do not certify the randomized total as the long-term observed or analyzed denominator.", "uncertainty": "External abstracts, full texts, registration, protocol and SAP unread; no new calculations or clinical-content review performed", "review_date": null, "reading_status": "Full text not read · Stored summary read", "additional_material": "Long-term full-cohort participant flow, eligibility and analysis tables" }, { "item_id": "N03", "question_type": "Comparative efficacy, work participation and time points", "question": "Is the 10-to-46-month observation window the same as the original program duration?", "needed": "Extension time points, duration, observation window, termination and exposure", "role": "Required", "role_reason": "Production condition separating direct material and gaps for the selected time point, full cohort/subgroups and work outcome", "application_exception": "Other time points, subgroups, questionnaires, services or denominators do not fill unresolved information in the selected material", "criterion": "Extension time points, duration, observation window, termination and exposure; preserve only original values, direct observations, scope and gaps without creating new effects, verdicts, calculations or independence certification.", "basis": "Linkage to preserved methodology-application records; full-definition content review and official certification incomplete", "condition_origin": "Chamgap-specific application condition; review of existing content incomplete", "proposed_research": "Distinguish treatment exposure from observation duration", "current_reports": [ "R01", "R02" ], "existence": "Related original wording, citations and context appear in the preserved existing summary; detailed external material is unverified", "acquired_read": "Summary read; related external material unread", "observation": "The long-term report covers an extension over 10 to 46 months. The original combined service included up to 15 CBT sessions and individual job support.", "condition_status": "Partly verified", "status_reason": "Stored-summary information, scope and gaps displayed; not completed content review or a new clinical verdict", "missingness": "Do not describe 10 to 46 months as continuous treatment or an exact interval since treatment ended. Individual exposure and follow-up-window details remain unverified.", "uncertainty": "External abstracts, full texts, registration, protocol and SAP unread; no new calculations or clinical-content review performed", "review_date": null, "reading_status": "Full text not read · Stored summary read", "additional_material": "Extension observation windows, original treatment duration and additional exposure data" }, { "item_id": "N04", "question_type": "Comparative efficacy, work participation and time points", "question": "Are the original combined service and usual care preserved accurately?", "needed": "Specifications of CBT, job support, usual care and additional management", "role": "Required", "role_reason": "Production condition separating direct material and gaps for the selected time point, full cohort/subgroups and work outcome", "application_exception": "Other time points, subgroups, questionnaires, services or denominators do not fill unresolved information in the selected material", "criterion": "Specifications of CBT, job support, usual care and additional management; preserve only original values, direct observations, scope and gaps without creating new effects, verdicts, calculations or independence certification.", "basis": "Linkage to preserved methodology-application records; full-definition content review and official certification incomplete", "condition_origin": "Chamgap-specific application condition; review of existing content incomplete", "proposed_research": "Show the scope of combined-service assignment and subsequent exposure", "current_reports": [ "R01", "R02" ], "existence": "Related original wording, citations and context appear in the preserved existing summary; detailed external material is unverified", "acquired_read": "Summary read; related external material unread", "observation": "The original allocation comparison was combined AWaC work-focused CBT and individual job support versus usual care.", "condition_status": "Partly verified", "status_reason": "Stored-summary information, scope and gaps displayed; not completed content review or a new clinical verdict", "missingness": "Do not convert this into CBT alone, job support alone or a no-treatment comparison. Long-term usual-care/additional-service details are unread; do not write treatment implementation instructions.", "uncertainty": "External abstracts, full texts, registration, protocol and SAP unread; no new calculations or clinical-content review performed", "review_date": null, "reading_status": "Full text not read · Stored summary read", "additional_material": "Original/additional services and arm-specific usual-care data" }, { "item_id": "N05", "question_type": "Comparative efficacy, work participation and time points", "question": "Are long-term income, work participation and months without benefits separate outcomes?", "needed": "Definitions, units, aggregation and periods for each long-term endpoint", "role": "Required", "role_reason": "Production condition separating direct material and gaps for the selected time point, full cohort/subgroups and work outcome", "application_exception": "Other time points, subgroups, questionnaires, services or denominators do not fill unresolved information in the selected material", "criterion": "Definitions, units, aggregation and periods for each long-term endpoint; preserve only original values, direct observations, scope and gaps without creating new effects, verdicts, calculations or independence certification.", "basis": "Linkage to preserved methodology-application records; full-definition content review and official certification incomplete", "condition_origin": "Chamgap-specific application condition; review of existing content incomplete", "proposed_research": "Present income, work and periods without benefits separately", "current_reports": [ "R02" ], "existence": "Related original wording, citations and context appear in the preserved existing summary; detailed external material is unverified", "acquired_read": "Summary read; related external material unread", "observation": "The preserved counterview states that full-cohort differences in income, work participation and months without benefits were not significant.", "condition_status": "Partly verified", "status_reason": "Stored-summary information, scope and gaps displayed; not completed content review or a new clinical verdict", "missingness": "Do not combine the three endpoints into one score or equate work, benefits and income. Detailed definitions, units and measurement windows are unread.", "uncertainty": "External abstracts, full texts, registration, protocol and SAP unread; no new calculations or clinical-content review performed", "review_date": null, "reading_status": "Full text not read · Stored summary read", "additional_material": "Long-term endpoint definitions, data and original result tables" }, { "item_id": "N06", "question_type": "Comparative efficacy, work participation and time points", "question": "Are long-term full-cohort effect estimates, CIs and P values provided?", "needed": "Endpoint-specific direct differences, ratios, intervals, tests and models", "role": "Required", "role_reason": "Production condition separating direct material and gaps for the selected time point, full cohort/subgroups and work outcome", "application_exception": "Other time points, subgroups, questionnaires, services or denominators do not fill unresolved information in the selected material", "criterion": "Endpoint-specific direct differences, ratios, intervals, tests and models; preserve only original values, direct observations, scope and gaps without creating new effects, verdicts, calculations or independence certification.", "basis": "Linkage to preserved methodology-application records; full-definition content review and official certification incomplete", "condition_origin": "Chamgap-specific application condition; review of existing content incomplete", "proposed_research": "Distinguish the qualitative null account from gaps in direct numerical results", "current_reports": [ "R02" ], "existence": "Related original wording, citations and context appear in the preserved existing summary; detailed external material is unverified", "acquired_read": "Summary read; related external material unread", "observation": "The preserved long-term account provides qualitative information that full-cohort differences in the three outcomes were not significant.", "condition_status": "Partly verified", "status_reason": "Stored-summary information, scope and gaps displayed; not completed content review or a new clinical verdict", "missingness": "Exact long-term full-cohort effects, CIs and P values are absent from the summary. Do not copy the 12-month +6.2 percentage points or 18-month +7.8 percentage points as long-term estimates.", "uncertainty": "External abstracts, full texts, registration, protocol and SAP unread; no new calculations or clinical-content review performed", "review_date": null, "reading_status": "Full text not read · Stored summary read", "additional_material": "Original long-term endpoint effect, interval and P-value tables" }, { "item_id": "N07", "question_type": "Comparative efficacy, work participation and time points", "question": "Has a null long-term result been turned into exact zero, equivalence or exclusion of every benefit?", "needed": "Long-term question, intervals, comparison criteria and original interpretation", "role": "Required", "role_reason": "Production condition separating direct material and gaps for the selected time point, full cohort/subgroups and work outcome", "application_exception": "Other time points, subgroups, questionnaires, services or denominators do not fill unresolved information in the selected material", "criterion": "Long-term question, intervals, comparison criteria and original interpretation; preserve only original values, direct observations, scope and gaps without creating new effects, verdicts, calculations or independence certification.", "basis": "Linkage to preserved methodology-application records; full-definition content review and official certification incomplete", "condition_origin": "Chamgap-specific application condition; review of existing content incomplete", "proposed_research": "Distinguish a null finding from exclusion and equivalence", "current_reports": [ "R02" ], "existence": "Related original wording, citations and context appear in the preserved existing summary; detailed external material is unverified", "acquired_read": "Summary read; related external material unread", "observation": "The selected note and counterview record a null full-cohort result and unverified durable benefit.", "condition_status": "Partly verified", "status_reason": "Stored-summary information, scope and gaps displayed; not completed content review or a new clinical verdict", "missingness": "This does not certify an exactly zero effect, exclusion of all meaningful benefit or equivalence to the comparator. Prespecified long-term important-difference/equivalence criteria are also unverified.", "uncertainty": "External abstracts, full texts, registration, protocol and SAP unread; no new calculations or clinical-content review performed", "review_date": null, "reading_status": "Full text not read · Stored summary read", "additional_material": "Original long-term analyses, importance and comparison criteria" }, { "item_id": "N08", "question_type": "Comparative efficacy, work participation and time points", "question": "What are the definition and denominators of the long-term-benefit subgroup?", "needed": "Subgroup baseline status, duration, criteria, participants and denominators", "role": "Required", "role_reason": "Production condition separating direct material and gaps for the selected time point, full cohort/subgroups and work outcome", "application_exception": "Other time points, subgroups, questionnaires, services or denominators do not fill unresolved information in the selected material", "criterion": "Subgroup baseline status, duration, criteria, participants and denominators; preserve only original values, direct observations, scope and gaps without creating new effects, verdicts, calculations or independence certification.", "basis": "Linkage to preserved methodology-application records; full-definition content review and official certification incomplete", "condition_origin": "Chamgap-specific application condition; review of existing content incomplete", "proposed_research": "Distinguish direct evidence for the full cohort from evidence for the precisely defined subgroup", "current_reports": [ "R02" ], "existence": "Related original wording, citations and context appear in the preserved existing summary; detailed external material is unverified", "acquired_read": "Summary read; related external material unread", "observation": "The long-term report states that only the long-term-benefit subgroup had significant results.", "condition_status": "Partly verified", "status_reason": "Stored-summary information, scope and gaps displayed; not completed content review or a new clinical verdict", "missingness": "Benefit types, the long-term criterion, subgroup counts, arm denominators and effects/CIs/P values are unverified. Do not invent criteria or values.", "uncertainty": "External abstracts, full texts, registration, protocol and SAP unread; no new calculations or clinical-content review performed", "review_date": null, "reading_status": "Full text not read · Stored summary read", "additional_material": "Subgroup definitions, baseline data, denominators and original effect tables" }, { "item_id": "N09", "question_type": "Comparative efficacy, work participation and time points", "question": "Does within-subgroup significance prove a full-cohort effect or interaction?", "needed": "Prespecified subgroup plans, multiplicity, effect differences and interactions", "role": "Required", "role_reason": "Production condition separating direct material and gaps for the selected time point, full cohort/subgroups and work outcome", "application_exception": "Other time points, subgroups, questionnaires, services or denominators do not fill unresolved information in the selected material", "criterion": "Prespecified subgroup plans, multiplicity, effect differences and interactions; preserve only original values, direct observations, scope and gaps without creating new effects, verdicts, calculations or independence certification.", "basis": "Linkage to preserved methodology-application records; full-definition content review and official certification incomplete", "condition_origin": "Chamgap-specific application condition; review of existing content incomplete", "proposed_research": "Distinguish within-subgroup results from direct between-group differences", "current_reports": [ "R02" ], "existence": "Related original wording, citations and context appear in the preserved existing summary; detailed external material is unverified", "acquired_read": "Summary read; related external material unread", "observation": "The original account describes a null full-cohort result and significance only in some long-term-benefit subgroup results.", "condition_status": "Partly verified", "status_reason": "Stored-summary information, scope and gaps displayed; not completed content review or a new clinical verdict", "missingness": "A subgroup signal does not establish full-cohort superiority or between-subgroup differences/interactions. Plans, tests and multiplicity are unread.", "uncertainty": "External abstracts, full texts, registration, protocol and SAP unread; no new calculations or clinical-content review performed", "review_date": null, "reading_status": "Full text not read · Stored summary read", "additional_material": "Original subgroup plans, multiplicity and interaction data" }, { "item_id": "N10", "question_type": "Comparative efficacy, work participation and time points", "question": "Are 12-month maintenance/restoration and the long-term full-cohort results the same endpoint?", "needed": "Time-specific classifications, data, estimands and populations", "role": "Required", "role_reason": "Production condition separating direct material and gaps for the selected time point, full cohort/subgroups and work outcome", "application_exception": "Other time points, subgroups, questionnaires, services or denominators do not fill unresolved information in the selected material", "criterion": "Time-specific classifications, data, estimands and populations; preserve only original values, direct observations, scope and gaps without creating new effects, verdicts, calculations or independence certification.", "basis": "Linkage to preserved methodology-application records; full-definition content review and official certification incomplete", "condition_origin": "Chamgap-specific application condition; review of existing content incomplete", "proposed_research": "Separate direct short-term effects from estimates for each long-term endpoint", "current_reports": [ "R01", "R02" ], "existence": "Related original wording, citations and context appear in the preserved existing summary; detailed external material is unverified", "acquired_read": "Summary read; related external material unread", "observation": "At 12 months, maintenance/increase was 44.2% versus 37.2%, with an unadjusted 6.9-percentage-point difference (P=.015) and adjusted +6.2 percentage points (95% CI +0.5 to +11.8). The long-term account concerns income, work and months without benefits.", "condition_status": "Partly verified", "status_reason": "Stored-summary information, scope and gaps displayed; not completed content review or a new clinical verdict", "missingness": "Do not transfer short-term classifications, unadjusted/adjusted estimates or denominators to other long-term outcomes. Do not calculate sustained-maintenance or relapse/return-to-work rates.", "uncertainty": "External abstracts, full texts, registration, protocol and SAP unread; no new calculations or clinical-content review performed", "review_date": null, "reading_status": "Full text not read · Stored summary read", "additional_material": "Original time-specific work classifications, denominators and effect tables" }, { "item_id": "N11", "question_type": "Comparative efficacy, work participation and time points", "question": "Does the observed 18-month difference confirm long-term full-cohort benefit?", "needed": "18-month observations and 10-to-46-month extension models and denominators", "role": "Required", "role_reason": "Production condition separating direct material and gaps for the selected time point, full cohort/subgroups and work outcome", "application_exception": "Other time points, subgroups, questionnaires, services or denominators do not fill unresolved information in the selected material", "criterion": "18-month observations and 10-to-46-month extension models and denominators; preserve only original values, direct observations, scope and gaps without creating new effects, verdicts, calculations or independence certification.", "basis": "Linkage to preserved methodology-application records; full-definition content review and official certification incomplete", "condition_origin": "Chamgap-specific application condition; review of existing content incomplete", "proposed_research": "Distinguish an observation time point from the scope of long-term analysis", "current_reports": [ "R01", "R02" ], "existence": "Related original wording, citations and context appear in the preserved existing summary; detailed external material is unverified", "acquired_read": "Summary read; related external material unread", "observation": "The original product-facts account records an observed +7.8-percentage-point difference at 18 months (P=.018) and explicitly leaves long-term full-cohort superiority unverified.", "condition_status": "Partly verified", "status_reason": "Stored-summary information, scope and gaps displayed; not completed content review or a new clinical verdict", "missingness": "The 18-month CI, denominators and adjustment details are absent. Do not promote a single-time-point difference to a whole-period long-term effect or independent replication.", "uncertainty": "External abstracts, full texts, registration, protocol and SAP unread; no new calculations or clinical-content review performed", "review_date": null, "reading_status": "Full text not read · Stored summary read", "additional_material": "18-month and long-term models, denominators and interval data" }, { "item_id": "N12", "question_type": "Comparative efficacy, work participation and time points", "question": "Has zero 12-month follow-up loss been reused as complete long-term follow-up?", "needed": "Long-term register linkage, observation, losses and endpoint-specific denominators", "role": "Required", "role_reason": "Production condition separating direct material and gaps for the selected time point, full cohort/subgroups and work outcome", "application_exception": "Other time points, subgroups, questionnaires, services or denominators do not fill unresolved information in the selected material", "criterion": "Long-term register linkage, observation, losses and endpoint-specific denominators; preserve only original values, direct observations, scope and gaps without creating new effects, verdicts, calculations or independence certification.", "basis": "Linkage to preserved methodology-application records; full-definition content review and official certification incomplete", "condition_origin": "Chamgap-specific application condition; review of existing content incomplete", "proposed_research": "Present the actual scope of complete follow-up at each time point separately", "current_reports": [ "R02" ], "existence": "Related original wording, citations and context appear in the preserved existing summary; detailed external material is unverified", "acquired_read": "Summary read; related external material unread", "observation": "Complete register outcomes for 1,193 participants and loss of 0/1,193 are original information about the 12-month primary outcome.", "condition_status": "Partly verified", "status_reason": "Stored-summary information, scope and gaps displayed; not completed content review or a new clinical verdict", "missingness": "Sharing a cohort does not certify zero data loss for every long-term endpoint and period. Long-term denominator details are unread.", "uncertainty": "External abstracts, full texts, registration, protocol and SAP unread; no new calculations or clinical-content review performed", "review_date": null, "reading_status": "Full text not read · Stored summary read", "additional_material": "Long-term endpoint observations, register linkage and analysis denominators" }, { "item_id": "N13", "question_type": "Comparative efficacy, work participation and time points", "question": "Are long-term register data and handling of missingness, movement and benefit status known?", "needed": "Register definitions, linkage, missingness, status changes and measurement error", "role": "Required", "role_reason": "Production condition separating direct material and gaps for the selected time point, full cohort/subgroups and work outcome", "application_exception": "Other time points, subgroups, questionnaires, services or denominators do not fill unresolved information in the selected material", "criterion": "Register definitions, linkage, missingness, status changes and measurement error; preserve only original values, direct observations, scope and gaps without creating new effects, verdicts, calculations or independence certification.", "basis": "Linkage to preserved methodology-application records; full-definition content review and official certification incomplete", "condition_origin": "Chamgap-specific application condition; review of existing content incomplete", "proposed_research": "Distinguish objective ascertainment from actual processing limitations", "current_reports": [ "R02" ], "existence": "Related original wording, citations and context appear in the preserved existing summary; detailed external material is unverified", "acquired_read": "Summary read; related external material unread", "observation": "The parent rationale describes monthly work and benefit status ascertained through national social-insurance and employment registers.", "condition_status": "Unverified", "status_reason": "Stored-summary information, scope and gaps displayed; not completed content review or a new clinical verdict", "missingness": "Long-term missingness, movement, data errors, benefit-classification changes and processing methods are absent from the summary. Objective data do not establish absence of every error.", "uncertainty": "External abstracts, full texts, registration, protocol and SAP unread; no new calculations or clinical-content review performed", "review_date": null, "reading_status": "Full text not read · Stored summary read", "additional_material": "Original long-term register-processing, error and missingness specifications" }, { "item_id": "N14", "question_type": "Comparative efficacy, work participation and time points", "question": "Are long-term estimands, covariates and statistical models verified?", "needed": "Long-term analysis populations, models, adjustment, repeated data and periods", "role": "Required", "role_reason": "Production condition separating direct material and gaps for the selected time point, full cohort/subgroups and work outcome", "application_exception": "Other time points, subgroups, questionnaires, services or denominators do not fill unresolved information in the selected material", "criterion": "Long-term analysis populations, models, adjustment, repeated data and periods; preserve only original values, direct observations, scope and gaps without creating new effects, verdicts, calculations or independence certification.", "basis": "Linkage to preserved methodology-application records; full-definition content review and official certification incomplete", "condition_origin": "Chamgap-specific application condition; review of existing content incomplete", "proposed_research": "Distinguish short-term and long-term estimands and models", "current_reports": [ "R02" ], "existence": "Related original wording, citations and context appear in the preserved existing summary; detailed external material is unverified", "acquired_read": "Summary read; related external material unread", "observation": "Information that the long-term full-cohort result was not significant coexists with the original prespecified adjusted 12-month effect.", "condition_status": "Unverified", "status_reason": "Stored-summary information, scope and gaps displayed; not completed content review or a new clinical verdict", "missingness": "Do not automatically apply 12-month models/prespecified covariates to the long-term analysis or label it an effect of all observations or actual participation. Long-term model details are unread.", "uncertainty": "External abstracts, full texts, registration, protocol and SAP unread; no new calculations or clinical-content review performed", "review_date": null, "reading_status": "Full text not read · Stored summary read", "additional_material": "Long-term models, covariates, repeated-data handling and analysis populations" }, { "item_id": "N15", "question_type": "Comparative efficacy, work participation and time points", "question": "Are original allocation implementation and long-term selection/cross-exposure distinguished?", "needed": "Allocation, follow-up selection, additional services, concomitant treatment and arm changes", "role": "Required", "role_reason": "Production condition separating direct material and gaps for the selected time point, full cohort/subgroups and work outcome", "application_exception": "Other time points, subgroups, questionnaires, services or denominators do not fill unresolved information in the selected material", "criterion": "Allocation, follow-up selection, additional services, concomitant treatment and arm changes; preserve only original values, direct observations, scope and gaps without creating new effects, verdicts, calculations or independence certification.", "basis": "Linkage to preserved methodology-application records; full-definition content review and official certification incomplete", "condition_origin": "Chamgap-specific application condition; review of existing content incomplete", "proposed_research": "Distinguish original allocation from limitations of actual long-term exposure/observation", "current_reports": [ "R01", "R02" ], "existence": "Related original wording, citations and context appear in the preserved existing summary; detailed external material is unverified", "acquired_read": "Summary read; related external material unread", "observation": "The original trial is described as a six-center pragmatic randomized trial with independent allocation, unmasked participants and register-based outcome ascertainment.", "condition_status": "Partly verified", "status_reason": "Stored-summary information, scope and gaps displayed; not completed content review or a new clinical verdict", "missingness": "Do not make the extension a new randomized trial. Details of follow-up selection, additional services, arm changes and concomitant exposure remain unverified.", "uncertainty": "External abstracts, full texts, registration, protocol and SAP unread; no new calculations or clinical-content review performed", "review_date": null, "reading_status": "Full text not read · Stored summary read", "additional_material": "Original long-term participation, exposure changes, services and register data" }, { "item_id": "N16", "question_type": "Comparative efficacy, work participation and time points", "question": "Has the 5% treatment-participation figure been combined with long-term work denominators?", "needed": "Attendance, stopping, reasons, timing and long-term register observation", "role": "Required", "role_reason": "Production condition separating direct material and gaps for the selected time point, full cohort/subgroups and work outcome", "application_exception": "Other time points, subgroups, questionnaires, services or denominators do not fill unresolved information in the selected material", "criterion": "Attendance, stopping, reasons, timing and long-term register observation; preserve only original values, direct observations, scope and gaps without creating new effects, verdicts, calculations or independence certification.", "basis": "Linkage to preserved methodology-application records; full-definition content review and official certification incomplete", "condition_origin": "Chamgap-specific application condition; review of existing content incomplete", "proposed_research": "Distinguish service participation from register-outcome follow-up", "current_reports": [ "R01", "R02" ], "existence": "Related original wording, citations and context appear in the preserved existing summary; detailed external material is unverified", "acquired_read": "Summary read; related external material unread", "observation": "The original safety account describes 5% as stopping treatment/attending fewer than 3 AWaC sessions.", "condition_status": "Partly verified", "status_reason": "Stored-summary information, scope and gaps displayed; not completed content review or a new clinical verdict", "missingness": "Do not convert 5% to long-term loss, harm incidence or a denominator for all work outcomes, or calculate counts using the randomized total. Long-term participation/exposure denominators are separate.", "uncertainty": "External abstracts, full texts, registration, protocol and SAP unread; no new calculations or clinical-content review performed", "review_date": null, "reading_status": "Full text not read · Stored summary read", "additional_material": "Treatment attendance/stopping and long-term data flow" }, { "item_id": "N17", "question_type": "Comparative efficacy, work participation and time points", "question": "Are long-term full-cohort/subgroup plans distinct from the original primary-outcome plan?", "needed": "Protocol, SAP, registration history, long-term endpoints and hierarchy", "role": "Required", "role_reason": "Production condition separating direct material and gaps for the selected time point, full cohort/subgroups and work outcome", "application_exception": "Other time points, subgroups, questionnaires, services or denominators do not fill unresolved information in the selected material", "criterion": "Protocol, SAP, registration history, long-term endpoints and hierarchy; preserve only original values, direct observations, scope and gaps without creating new effects, verdicts, calculations or independence certification.", "basis": "Linkage to preserved methodology-application records; full-definition content review and official certification incomplete", "condition_origin": "Chamgap-specific application condition; review of existing content incomplete", "proposed_research": "Separate original primary-outcome plans from long-term and subgroup plans", "current_reports": [ "R01", "R02", "R03" ], "existence": "Related original wording, citations and context appear in the preserved existing summary; detailed external material is unverified", "acquired_read": "Summary read; related external material unread", "observation": "The original primary outcome is objective work participation at 12 months, described as matching NCT01146730. The long-term report is an extension of the same trial.", "condition_status": "Partly verified", "status_reason": "Stored-summary information, scope and gaps displayed; not completed content review or a new clinical verdict", "missingness": "Do not reuse original primary-outcome prespecification as certification of long-term endpoints or subgroup plans. Long-term plans, changes and multiplicity remain externally unread.", "uncertainty": "External abstracts, full texts, registration, protocol and SAP unread; no new calculations or clinical-content review performed", "review_date": null, "reading_status": "Full text not read · Stored summary read", "additional_material": "Registration, long-term plans, SAP and amendment documents" }, { "item_id": "N18", "question_type": "Comparative efficacy, work participation and time points", "question": "Have long-term importance, clinical function and economic results been invented?", "needed": "Definitions and importance of income, work and months without benefits, and other outcomes", "role": "Required", "role_reason": "Production condition separating direct material and gaps for the selected time point, full cohort/subgroups and work outcome", "application_exception": "Other time points, subgroups, questionnaires, services or denominators do not fill unresolved information in the selected material", "criterion": "Definitions and importance of income, work and months without benefits, and other outcomes; preserve only original values, direct observations, scope and gaps without creating new effects, verdicts, calculations or independence certification.", "basis": "Linkage to preserved methodology-application records; full-definition content review and official certification incomplete", "condition_origin": "Chamgap-specific application condition; review of existing content incomplete", "proposed_research": "Distinguish direct long-term endpoints from gaps in other outcomes and importance", "current_reports": [ "R02" ], "existence": "Related original wording, citations and context appear in the preserved existing summary; detailed external material is unverified", "acquired_read": "Summary read; related external material unread", "observation": "The follow-up citation concerns long-term income and sickness benefits; the preserved account records null full-cohort results for three outcomes.", "condition_status": "Partly verified", "status_reason": "Stored-summary information, scope and gaps displayed; not completed content review or a new clinical verdict", "missingness": "Do not create new effects, economic costs, quality-of-life outcomes, symptom remission, individual examples or clinical minimum thresholds. Direct data for each outcome are separately needed.", "uncertainty": "External abstracts, full texts, registration, protocol and SAP unread; no new calculations or clinical-content review performed", "review_date": null, "reading_status": "Full text not read · Stored summary read", "additional_material": "Original long-term work, economic and clinical-function results" }, { "item_id": "N19", "question_type": "Comparative efficacy, work participation and time points", "question": "Are three same-cohort citations, registration and sibling sheets independent replication?", "needed": "Links among original/long-term reports, registration, participants and repeated data", "role": "Required", "role_reason": "Production condition separating direct material and gaps for the selected time point, full cohort/subgroups and work outcome", "application_exception": "Other time points, subgroups, questionnaires, services or denominators do not fill unresolved information in the selected material", "criterion": "Links among original/long-term reports, registration, participants and repeated data; preserve only original values, direct observations, scope and gaps without creating new effects, verdicts, calculations or independence certification.", "basis": "Linkage to preserved methodology-application records; full-definition content review and official certification incomplete", "condition_origin": "Chamgap-specific application condition; review of existing content incomplete", "proposed_research": "Distinguish report slots from actual trial and participant units", "current_reports": [ "R01", "R02", "R03" ], "existence": "Related original wording, citations and context appear in the preserved existing summary; detailed external material is unverified", "acquired_read": "Summary read; related external material unread", "observation": "The original evidence describes AWaC and the same-trial long-term report; the 3 citations comprise the original report, long-term report and registration.", "condition_status": "Partly verified", "status_reason": "Stored-summary information, scope and gaps displayed; not completed content review or a new clinical verdict", "missingness": "Do not sum 3 reports, sibling sheets, monthly data, centers or arms as new independent trials or participants. Confirmed trial/participant counts are unrecorded.", "uncertainty": "External abstracts, full texts, registration, protocol and SAP unread; no new calculations or clinical-content review performed", "review_date": null, "reading_status": "Full text not read · Stored summary read", "additional_material": "Original/long-term report, registration and participant-linkage data" }, { "item_id": "N20", "question_type": "Comparative efficacy, work participation and time points", "question": "Has the result been extended to other services, populations or countries?", "needed": "Direct data for each combined service, delivery system, population and institutional setting", "role": "Required", "role_reason": "Production condition separating direct material and gaps for the selected time point, full cohort/subgroups and work outcome", "application_exception": "Other time points, subgroups, questionnaires, services or denominators do not fill unresolved information in the selected material", "criterion": "Direct data for each combined service, delivery system, population and institutional setting; preserve only original values, direct observations, scope and gaps without creating new effects, verdicts, calculations or independence certification.", "basis": "Linkage to preserved methodology-application records; full-definition content review and official certification incomplete", "condition_origin": "Chamgap-specific application condition; review of existing content incomplete", "proposed_research": "Distinguish original related context from the selected long-term full-cohort question", "current_reports": [ "R01", "R02" ], "existence": "Related original wording, citations and context appear in the preserved existing summary; detailed external material is unverified", "acquired_read": "Summary read; related external material unread", "observation": "The evidence concerns the combined Norwegian AWaC service. The preserved summary describes different delivery systems and populations for verdict 2944 on physiotherapist vocational advice.", "condition_status": "Partly verified", "status_reason": "Stored-summary information, scope and gaps displayed; not completed content review or a new clinical verdict", "missingness": "Related verdicts/links have not been newly read or checked. Do not turn the long-term null result into a null result for every CBT, job-support or vocational-advice service.", "uncertainty": "External abstracts, full texts, registration, protocol and SAP unread; no new calculations or clinical-content review performed", "review_date": null, "reading_status": "Full text not read · Stored summary read", "additional_material": "Direct comparative data for services, institutions and populations" }, { "item_id": "N21", "question_type": "Comparative efficacy, work participation and time points", "question": "Have long-term effects in excluded severe or high-risk populations been filled in?", "needed": "Baseline risk, diagnosis, exclusions and long-term-subgroup eligibility", "role": "Required", "role_reason": "Production condition separating direct material and gaps for the selected time point, full cohort/subgroups and work outcome", "application_exception": "Other time points, subgroups, questionnaires, services or denominators do not fill unresolved information in the selected material", "criterion": "Baseline risk, diagnosis, exclusions and long-term-subgroup eligibility; preserve only original values, direct observations, scope and gaps without creating new effects, verdicts, calculations or independence certification.", "basis": "Linkage to preserved methodology-application records; full-definition content review and official certification incomplete", "condition_origin": "Chamgap-specific application condition; review of existing content incomplete", "proposed_research": "Distinguish long-term economic/benefit subgroups from populations defined by clinical risk", "current_reports": [ "R02" ], "existence": "Related original wording, citations and context appear in the preserved existing summary; detailed external material is unverified", "acquired_read": "Summary read; related external material unread", "observation": "The original material states that high suicide risk, severe mental illness and active substance use were excluded.", "condition_status": "Partly verified", "status_reason": "Stored-summary information, scope and gaps displayed; not completed content review or a new clinical verdict", "missingness": "Do not certify long-term effects, safety or treatment suitability in excluded populations. Do not equate the long-term-benefit subgroup with a severe-mental-illness population.", "uncertainty": "External abstracts, full texts, registration, protocol and SAP unread; no new calculations or clinical-content review performed", "review_date": null, "reading_status": "Full text not read · Stored summary read", "additional_material": "Original baseline, exclusion and long-term-subgroup eligibility data" }, { "item_id": "N22", "question_type": "Comparative efficacy, work participation and time points", "question": "Are public funding, NAV operation and independent evaluation distinguished for long-term roles?", "needed": "Original/long-term funding, operation, evaluation and data-control disclosures", "role": "Required", "role_reason": "Production condition separating direct material and gaps for the selected time point, full cohort/subgroups and work outcome", "application_exception": "Other time points, subgroups, questionnaires, services or denominators do not fill unresolved information in the selected material", "criterion": "Original/long-term funding, operation, evaluation and data-control disclosures; preserve only original values, direct observations, scope and gaps without creating new effects, verdicts, calculations or independence certification.", "basis": "Linkage to preserved methodology-application records; full-definition content review and official certification incomplete", "condition_origin": "Chamgap-specific application condition; review of existing content incomplete", "proposed_research": "Record original support and long-term analytical roles separately", "current_reports": [ "R01", "R02" ], "existence": "Related original wording, citations and context appear in the preserved existing summary; detailed external material is unverified", "acquired_read": "Summary read; related external material unread", "observation": "The original summary describes full funding by the Ministries of Health and Labour, NAV center operation and an evaluation team uninvolved in center operation or treatment.", "condition_status": "Partly verified", "status_reason": "Stored-summary information, scope and gaps displayed; not completed content review or a new clinical verdict", "missingness": "Do not convert the original evaluation role into new certification of independence for every long-term analysis, data process or publication. Separate long-term disclosures are unread.", "uncertainty": "External abstracts, full texts, registration, protocol and SAP unread; no new calculations or clinical-content review performed", "review_date": null, "reading_status": "Full text not read · Stored summary read", "additional_material": "Original/long-term funding, operation, evaluation and authority disclosures" }, { "item_id": "N23", "question_type": "Comparative efficacy, work participation and time points", "question": "Have long-term authorship, analysis, writing, publication and company involvement been verified?", "needed": "Long-term disclosures, author relationships, analysis, writing, publication and data control", "role": "Required", "role_reason": "Production condition separating direct material and gaps for the selected time point, full cohort/subgroups and work outcome", "application_exception": "Other time points, subgroups, questionnaires, services or denominators do not fill unresolved information in the selected material", "criterion": "Long-term disclosures, author relationships, analysis, writing, publication and data control; preserve only original values, direct observations, scope and gaps without creating new effects, verdicts, calculations or independence certification.", "basis": "Linkage to preserved methodology-application records; full-definition content review and official certification incomplete", "condition_origin": "Chamgap-specific application condition; review of existing content incomplete", "proposed_research": "Distinguish reported support from unverified long-term roles", "current_reports": [ "R02" ], "existence": "Related original wording, citations and context appear in the preserved existing summary; detailed external material is unverified", "acquired_read": "Summary read; related external material unread", "observation": "The current preserved summary provides original public funding, operation/evaluation information and the long-term citation.", "condition_status": "Unverified", "status_reason": "Stored-summary information, scope and gaps displayed; not completed content review or a new clinical verdict", "missingness": "Do not certify that unmentioned long-term author relationships, outsourced analysis, medical writing, publication fees or other company involvement are all absent.", "uncertainty": "External abstracts, full texts, registration, protocol and SAP unread; no new calculations or clinical-content review performed", "review_date": null, "reading_status": "Full text not read · Stored summary read", "additional_material": "Long-term disclosures, contributions and data/publication authority" }, { "item_id": "N24", "question_type": "Supplementary harm evidence", "question": "Are long-term work data equivalent to collection of clinical safety outcomes?", "needed": "Prespecified harms, event collection, arm denominators and clinical follow-up", "role": "Supplementary", "role_reason": "Supplementary condition revealing harm collection, exposure and population scope separately from efficacy", "application_exception": "Other time points, subgroups, questionnaires, services or denominators do not fill unresolved information in the selected material", "criterion": "Prespecified harms, event collection, arm denominators and clinical follow-up; preserve only original values, direct observations, scope and gaps without creating new effects, verdicts, calculations or independence certification.", "basis": "Linkage to preserved methodology-application records; full-definition content review and official certification incomplete", "condition_origin": "Chamgap-specific application condition; review of existing content incomplete", "proposed_research": "Separate long-term work endpoints from clinical safety data", "current_reports": [ "R01", "R02" ], "existence": "Related original wording, citations and context appear in the preserved existing summary; detailed external material is unverified", "acquired_read": "Summary read; related external material unread", "observation": "The parent safety account states that prespecified safety endpoints and a serious-event comparison table were absent, leaving safety unknown.", "condition_status": "Partly verified", "status_reason": "Stored-summary information, scope and gaps displayed; not completed content review or a new clinical verdict", "missingness": "Having long-term work registers does not establish complete clinical-harm collection, no events or equivalence to the comparator.", "uncertainty": "External abstracts, full texts, registration, protocol and SAP unread; no new calculations or clinical-content review performed", "review_date": null, "reading_status": "Full text not read · Stored summary read", "additional_material": "Long-term arm-specific harms, collection and exposure data" }, { "item_id": "N25", "question_type": "Supplementary harm evidence", "question": "Are long-term/rare harms and reasons for stopping separately verified?", "needed": "Long-term exposure, events, stopping, other causes and rare outcomes", "role": "Supplementary", "role_reason": "Supplementary condition revealing harm collection, exposure and population scope separately from efficacy", "application_exception": "Other time points, subgroups, questionnaires, services or denominators do not fill unresolved information in the selected material", "criterion": "Long-term exposure, events, stopping, other causes and rare outcomes; preserve only original values, direct observations, scope and gaps without creating new effects, verdicts, calculations or independence certification.", "basis": "Linkage to preserved methodology-application records; full-definition content review and official certification incomplete", "condition_origin": "Chamgap-specific application condition; review of existing content incomplete", "proposed_research": "Distinguish participation/stopping from gaps in direct harm and causation", "current_reports": [ "R02" ], "existence": "Related original wording, citations and context appear in the preserved existing summary; detailed external material is unverified", "acquired_read": "Summary read; related external material unread", "observation": "The original 5% attending fewer than 3 sessions and exclusion of high-risk participants provide limited information.", "condition_status": "Unverified", "status_reason": "Stored-summary information, scope and gaps displayed; not completed content review or a new clinical verdict", "missingness": "Do not automatically classify stopping as harm or efficacy failure, or infer absence of long-term/rare harms. Do not create treatment implementation/change guidance.", "uncertainty": "External abstracts, full texts, registration, protocol and SAP unread; no new calculations or clinical-content review performed", "review_date": null, "reading_status": "Full text not read · Stored summary read", "additional_material": "Long-term stopping, reasons, events and exposure follow-up" }, { "item_id": "N26", "question_type": "Comparative efficacy, work participation and time points", "question": "Were actual long-term reports and registration documents read?", "needed": "Citations, original URLs, preserved summary and abstract/full-text/registration/plan status", "role": "Required", "role_reason": "Production condition separating direct material and gaps for the selected time point, full cohort/subgroups and work outcome", "application_exception": "Other time points, subgroups, questionnaires, services or denominators do not fill unresolved information in the selected material", "criterion": "Citations, original URLs, preserved summary and abstract/full-text/registration/plan status; preserve only original values, direct observations, scope and gaps without creating new effects, verdicts, calculations or independence certification.", "basis": "Linkage to preserved methodology-application records; full-definition content review and official certification incomplete", "condition_origin": "Chamgap-specific application condition; review of existing content incomplete", "proposed_research": "Show summary reading separately from each category of externally unread material", "current_reports": [ "R01", "R02", "R03" ], "existence": "Related original wording, citations and context appear in the preserved existing summary; detailed external material is unverified", "acquired_read": "Summary read; related external material unread", "observation": "The material read was the whole parent summary. Original/long-term PubMed and official NCT URLs are linked as originally cited.", "condition_status": "Partly verified", "status_reason": "Stored-summary information, scope and gaps displayed; not completed content review or a new clinical verdict", "missingness": "External abstracts, full texts, registration, protocol and SAP were not read; links/screens were not checked clinically. URL presence does not establish external reading or clinical QA.", "uncertainty": "External abstracts, full texts, registration, protocol and SAP unread; no new calculations or clinical-content review performed", "review_date": null, "reading_status": "Full text not read · Stored summary read", "additional_material": "Original/long-term reports, registration and plan materials" }, { "item_id": "N27", "question_type": "Comparative efficacy, work participation and time points", "question": "Are the long-term subclaim and parent Korean/English text, axes, dates and corrections distinguished?", "needed": "Whole parent original, long-term row, evidence date and corrections", "role": "Required", "role_reason": "Production condition separating direct material and gaps for the selected time point, full cohort/subgroups and work outcome", "application_exception": "Other time points, subgroups, questionnaires, services or denominators do not fill unresolved information in the selected material", "criterion": "Whole parent original, long-term row, evidence date and corrections; preserve only original values, direct observations, scope and gaps without creating new effects, verdicts, calculations or independence certification.", "basis": "Linkage to preserved methodology-application records; full-definition content review and official certification incomplete", "condition_origin": "Chamgap-specific application condition; review of existing content incomplete", "proposed_research": "Distinguish original verdict/corrections from the selected long-term context", "current_reports": [ "R01", "R02", "R03" ], "existence": "Related original wording, citations and context appear in the preserved existing summary; detailed external material is unverified", "acquired_read": "Summary read; related external material unread", "observation": "The whole preserved summary retains Korean/English text, axes, the 2026-08-26 evidence date, empty corrections/deliberation and the long-term row.", "condition_status": "Partly verified", "status_reason": "Stored-summary information, scope and gaps displayed; not completed content review or a new clinical verdict", "missingness": "Do not fill the long-term row’s missing score, status or axes with parent B and 76 points. Do not replace the original evidence date with the current review date.", "uncertainty": "External abstracts, full texts, registration, protocol and SAP unread; no new calculations or clinical-content review performed", "review_date": null, "reading_status": "Full text not read · Stored summary read", "additional_material": "Original preserved summary and subclaim/parent history" }, { "item_id": "N28", "question_type": "Comparative efficacy, work participation and time points", "question": "Are the existing candidate, freezing/application and human review separated?", "needed": "Claim/record references, original candidate state and production events", "role": "Required", "role_reason": "Production condition separating direct material and gaps for the selected time point, full cohort/subgroups and work outcome", "application_exception": "Other time points, subgroups, questionnaires, services or denominators do not fill unresolved information in the selected material", "criterion": "Claim/record references, original candidate state and production events; preserve only original values, direct observations, scope and gaps without creating new effects, verdicts, calculations or independence certification.", "basis": "Linkage to preserved methodology-application records; full-definition content review and official certification incomplete", "condition_origin": "Chamgap-specific application condition; review of existing content incomplete", "proposed_research": "Distinguish saved production from human content review and clinical certification", "current_reports": [ "R01", "R02", "R03" ], "existence": "Related original wording, citations and context appear in the preserved existing summary; detailed external material is unverified", "acquired_read": "Summary read; related external material unread", "observation": "Only the existing selected unit is produced; claim and record references are distinguished. Candidate pending/eligible values are original history.", "condition_status": "Partly verified", "status_reason": "Stored-summary information, scope and gaps displayed; not completed content review or a new clinical verdict", "missingness": "Do not activate a review wait. Preserve incomplete original review, false completion flags, 0 new units and unrecorded final independent counts. Do not create new effects, verdicts or treatment instructions.", "uncertainty": "External abstracts, full texts, registration, protocol and SAP unread; no new calculations or clinical-content review performed", "review_date": null, "reading_status": "Full text not read · Stored summary read", "additional_material": "Existing selection and condition-freezing/application events" } ], "reports": [ { "report_id": "R01", "title": "Reme SE, et al. Occup Environ Med. 2015. PMID: 26251065.", "url": "https://pubmed.ncbi.nlm.nih.gov/26251065/", "report_type": "Stored summary of the original-trial paper citation", "existence": "Present in actual citations/related wording of the stored summary", "acquired_read": "Summary read; external abstracts, full texts, registration and plans unread", "independent_replication": "Same-cohort/registration linkage; not certification of unique trials/participants or independent replication", "observed_result": "The grade is B with 76 points. In AWaC, maintained/increased work participation at 12 months was 44.2% versus 37.2%, unadjusted difference 6.9 percentage points (P=.015), and prespecified covariate-adjusted marginal effect +6.2 percentage points (95% CI +0.5~+11.8).", "result_level": "AWaC objective 12-month work participation; original proportions/unadjusted/adjusted effects and complete register follow-up for the primary outcome", "source_evidence_date": "2026-08-26", "materials": [ { "material_type": "Stored summary", "public_status": "Summary read", "access_status": "Stored summary read", "acquired": true, "actually_read": "Summary read", "as_of": "2026-08-26", "qualification": "Material entries do not establish external acquisition, reading, checked links or unique-trial/participant certification; the official registration URL is linked only to its registration entry" }, { "material_type": "External abstract", "public_status": "Not read", "access_status": "External material unread", "acquired": false, "actually_read": "Not read", "as_of": "2026-08-26", "qualification": "Material entries do not establish external acquisition, reading, checked links or unique-trial/participant certification; the official registration URL is linked only to its registration entry" }, { "material_type": "External full text", "public_status": "Not read", "access_status": "External material unread", "acquired": false, "actually_read": "Not read", "as_of": "2026-08-26", "qualification": "Material entries do not establish external acquisition, reading, checked links or unique-trial/participant certification; the official registration URL is linked only to its registration entry" }, { "material_type": "Original registration", "public_status": "Not read", "access_status": "External material unread", "acquired": false, "actually_read": "Not read", "as_of": "2026-08-26", "qualification": "Material entries do not establish external acquisition, reading, checked links or unique-trial/participant certification; the official registration URL is linked only to its registration entry" }, { "material_type": "Protocol/SAP", "public_status": "Not read", "access_status": "External material unread", "acquired": false, "actually_read": "Not read", "as_of": "2026-08-26", "qualification": "Material entries do not establish external acquisition, reading, checked links or unique-trial/participant certification; the official registration URL is linked only to its registration entry" } ], "links": [ { "label": "PubMed", "url": "https://pubmed.ncbi.nlm.nih.gov/26251065/" } ] }, { "report_id": "R02", "title": "Long-term effects on income and sickness benefits after work-focused CBT and individual job support. PMID: 30032103.", "url": "https://pubmed.ncbi.nlm.nih.gov/30032103/", "report_type": "Stored summary of the same trial’s long-term paper citation", "existence": "Present in actual citations/related wording of the stored summary", "acquired_read": "Summary read; external abstracts, full texts, registration and plans unread", "independent_replication": "Same-cohort/registration linkage; not certification of unique trials/participants or independent replication", "observed_result": "The same-cohort 10~46-month extension found no significant full-cohort differences in income, work participation or months without benefits; only the long-term-benefit subgroup was significant. The established result concerns the full cohort at 12 months, not persistence of effect.", "result_level": "Same AWaC 10~46-month extension: null full-cohort results and long-term-benefit subgroup context; long-term denominators/original values unverified", "source_evidence_date": "2026-08-26", "materials": [ { "material_type": "Stored summary", "public_status": "Summary read", "access_status": "Stored summary read", "acquired": true, "actually_read": "Summary read", "as_of": "2026-08-26", "qualification": "Material entries do not establish external acquisition, reading, checked links or unique-trial/participant certification; the official registration URL is linked only to its registration entry" }, { "material_type": "External abstract", "public_status": "Not read", "access_status": "External material unread", "acquired": false, "actually_read": "Not read", "as_of": "2026-08-26", "qualification": "Material entries do not establish external acquisition, reading, checked links or unique-trial/participant certification; the official registration URL is linked only to its registration entry" }, { "material_type": "External full text", "public_status": "Not read", "access_status": "External material unread", "acquired": false, "actually_read": "Not read", "as_of": "2026-08-26", "qualification": "Material entries do not establish external acquisition, reading, checked links or unique-trial/participant certification; the official registration URL is linked only to its registration entry" }, { "material_type": "Original registration", "public_status": "Not read", "access_status": "External material unread", "acquired": false, "actually_read": "Not read", "as_of": "2026-08-26", "qualification": "Material entries do not establish external acquisition, reading, checked links or unique-trial/participant certification; the official registration URL is linked only to its registration entry" }, { "material_type": "Protocol/SAP", "public_status": "Not read", "access_status": "External material unread", "acquired": false, "actually_read": "Not read", "as_of": "2026-08-26", "qualification": "Material entries do not establish external acquisition, reading, checked links or unique-trial/participant certification; the official registration URL is linked only to its registration entry" } ], "links": [ { "label": "PubMed", "url": "https://pubmed.ncbi.nlm.nih.gov/30032103/" } ] }, { "report_id": "R03", "title": "NCT01146730. At Work and Coping.", "url": "https://clinicaltrials.gov/study/NCT01146730", "report_type": "Stored summary of the official registration citation", "existence": "Present in actual citations/related wording of the stored summary", "acquired_read": "Summary read; external abstracts, full texts, registration and plans unread", "independent_replication": "Same-cohort/registration linkage; not certification of unique trials/participants or independent replication", "observed_result": "Trial registration material.", "result_level": "Same AWaC registration citation; original planning text unread, not a new clinical results report", "source_evidence_date": "2026-08-26", "materials": [ { "material_type": "Stored summary", "public_status": "Summary read", "access_status": "Stored summary read", "acquired": true, "actually_read": "Summary read", "as_of": "2026-08-26", "qualification": "Material entries do not establish external acquisition, reading, checked links or unique-trial/participant certification; the official registration URL is linked only to its registration entry" }, { "material_type": "External abstract", "public_status": "Not read", "access_status": "External material unread", "acquired": false, "actually_read": "Not read", "as_of": "2026-08-26", "qualification": "Material entries do not establish external acquisition, reading, checked links or unique-trial/participant certification; the official registration URL is linked only to its registration entry" }, { "material_type": "External full text", "public_status": "Not read", "access_status": "External material unread", "acquired": false, "actually_read": "Not read", "as_of": "2026-08-26", "qualification": "Material entries do not establish external acquisition, reading, checked links or unique-trial/participant certification; the official registration URL is linked only to its registration entry" }, { "material_type": "Original registration", "public_status": "Not read", "access_status": "External material unread", "acquired": false, "actually_read": "Not read", "as_of": "2026-08-26", "qualification": "Material entries do not establish external acquisition, reading, checked links or unique-trial/participant certification; the official registration URL is linked only to its registration entry" }, { "material_type": "Protocol/SAP", "public_status": "Not read", "access_status": "External material unread", "acquired": false, "actually_read": "Not read", "as_of": "2026-08-26", "qualification": "Material entries do not establish external acquisition, reading, checked links or unique-trial/participant certification; the official registration URL is linked only to its registration entry" } ], "links": [ { "label": "Official source", "url": "https://clinicaltrials.gov/study/NCT01146730" } ] } ], "method_sources": [ { "id": "M03", "version": "Cochrane Handbook 6.5 (2024), chapter updated 2023-08", "url": "https://www.cochrane.org/authors/handbooks-and-manuals/handbook/current/chapter-03", "section": "§3.1, §3.2.1–3.2.3, MECIR C5/C7/C13", "official_principle": "Clearly record the question, eligibility conditions and reasons for changes, and distinguish variations in interventions.", "review_level": "Preserved methodological linkages reused for production; no current methodological reassessment or external link checks, and historical quality review is not inherited" }, { "id": "M04", "version": "Cochrane Handbook 6.5.1 (2025), chapter updated 2025-03", "url": "https://www.cochrane.org/authors/handbooks-and-manuals/handbook/current/chapter-04", "section": "§4.5, §4.6.1–4.6.3, MECIR C42", "official_principle": "Distinguish studies from reports and link them; do not omit a study solely because results are unreported.", "review_level": "Preserved methodological linkages reused for production; no current methodological reassessment or external link checks, and historical quality review is not inherited" }, { "id": "M08", "version": "Cochrane Handbook 6.5 (2024), chapter updated 2019-10", "url": "https://www.cochrane.org/authors/handbooks-and-manuals/handbook/current/chapter-08", "section": "§8.1–8.2.3, Table 8.2.a", "official_principle": "Define the outcome and effect of interest, then examine randomization, deviations, missing data, measurement and selective reporting.", "review_level": "Preserved methodological linkages reused for production; no current methodological reassessment or external link checks, and historical quality review is not inherited" }, { "id": "M15", "version": "Cochrane Handbook 6.5 (2024), chapter updated 2023-08", "url": "https://www.cochrane.org/authors/handbooks-and-manuals/handbook/current/chapter-15", "section": "§15.2.4, §15.3.1–15.3.3", "official_principle": "Distinguish effect estimates, intervals, importance and applicability. Sample size alone does not determine precision.", "review_level": "Preserved methodological linkages reused for production; no current methodological reassessment or external link checks, and historical quality review is not inherited" }, { "id": "M19", "version": "Cochrane Handbook 6.5 (2024), chapter updated 2019-10", "url": "https://www.cochrane.org/authors/handbooks-and-manuals/handbook/current/chapter-19", "section": "§19.1.2, §19.2.1–19.2.4", "official_principle": "Harm questions may require different designs, populations and follow-up from efficacy questions. Case reports do not establish incidence rates.", "review_level": "Preserved methodological linkages reused for production; no current methodological reassessment or external link checks, and historical quality review is not inherited" } ], "status_dictionary": { "Partly verified": "Some information exists in the preserved review summary; detailed original materials remain unverified. This does not certify a passed review or clinical efficacy.", "Unverified": "Detailed materials for the selected condition could not be established within the stored scope; this does not mean zero effect, zero studies or safety", "Review incomplete": "Review of existing content incomplete", "Met": "Use only within the relevant conditions after existing content review; no automatic designation in this preparation", "Not reported": "Distinguish only within materials actually read; do not turn unread external materials into unreported findings", "Inaccessible": "Not applied during this preparation because actual access was not tested", "Not applicable": "Use with a reason for non-applicability based on an explicit question boundary", "Conflicting data": "Judge after actual material comparison; review was not performed during this preparation", "Insufficient evidence for the conditions": "Do not use as a clinical grade encompassing currently unread materials" }, "study_overlap": { "state": "Unverified", "unique_trial_count": null, "unique_participant_count": null, "reason": "Main/long-term AWaC reports and registration linked by the original stored summary; three citations, repeated monthly records, arms and sibling sheets are not totaled as new trials/participants" }, "history": [ { "date": "2026-10-12", "kind": "Separation of public-facing pages and materials", "view_version": "1.0", "change": "Public reader pages and material were prepared from the existing 28 items. No new clinical searches, verification-state changes or scoring were performed." } ], "language": "en", "translation_date": "2026-10-12" }