{
  "schema_version": "chamgap-public-criteria-1.0",
  "title": "Ad libitum low-fat vegan composite diet × Sixteen-week weight loss versus no diet change — Evidence checklist",
  "language": "en",
  "translation_date": "2026-10-11",
  "criteria_version": "1.0",
  "criteria_date": "2026-10-06",
  "condition_origin": "Chamgap's own application conditions",
  "method_sources": [
    {
      "id": "M03",
      "version": "Cochrane Handbook 6.5 (2024), chapter updated 2023-08",
      "url": "https://www.cochrane.org/authors/handbooks-and-manuals/handbook/current/chapter-03",
      "section": "§3.1, §3.2.1–3.2.3, MECIR C5/C7/C13",
      "official_principle": "Clearly record the question, eligibility conditions and reasons for changes, and distinguish variations in interventions.",
      "review_level": "Preserved methodology connections were reused for preparation. No new review of methodological content, reassessment or external-link checks were performed."
    },
    {
      "id": "M04",
      "version": "Cochrane Handbook 6.5.1 (2025), chapter updated 2025-03",
      "url": "https://www.cochrane.org/authors/handbooks-and-manuals/handbook/current/chapter-04",
      "section": "§4.5, §4.6.1–4.6.3, MECIR C42",
      "official_principle": "Distinguish studies from reports and link them; do not omit a study solely because results are unreported.",
      "review_level": "Preserved methodology connections were reused for preparation. No new review of methodological content, reassessment or external-link checks were performed."
    },
    {
      "id": "M08",
      "version": "Cochrane Handbook 6.5 (2024), chapter updated 2019-10",
      "url": "https://www.cochrane.org/authors/handbooks-and-manuals/handbook/current/chapter-08",
      "section": "§8.1–8.2.3, Table 8.2.a",
      "official_principle": "Define the outcome and effect of interest, then examine randomization, deviations, missing data, measurement and selective reporting.",
      "review_level": "Preserved methodology connections were reused for preparation. No new review of methodological content, reassessment or external-link checks were performed."
    },
    {
      "id": "M15",
      "version": "Cochrane Handbook 6.5 (2024), chapter updated 2023-08",
      "url": "https://www.cochrane.org/authors/handbooks-and-manuals/handbook/current/chapter-15",
      "section": "§15.2.4, §15.3.1–15.3.3",
      "official_principle": "Distinguish effect estimates, intervals, importance and applicability. Sample size alone does not determine precision.",
      "review_level": "Preserved methodology connections were reused for preparation. No new review of methodological content, reassessment or external-link checks were performed."
    },
    {
      "id": "M19",
      "version": "Cochrane Handbook 6.5 (2024), chapter updated 2019-10",
      "url": "https://www.cochrane.org/authors/handbooks-and-manuals/handbook/current/chapter-19",
      "section": "§19.1.2, §19.2.1–19.2.4",
      "official_principle": "Harm questions may require different designs, populations and follow-up from efficacy questions. Case reports do not establish incidence rates.",
      "review_level": "Preserved methodology connections were reused for preparation. No new review of methodological content, reassessment or external-link checks were performed."
    }
  ],
  "status_dictionary": {
    "Partly verified": "Some information exists in the preserved review summary; detailed original materials remain unverified. This does not certify a passed review or clinical efficacy.",
    "Unverified": "Detailed materials for the selected condition could not be established within the stored scope; this does not mean zero effect, zero studies or safety",
    "Review incomplete": "Review of existing content incomplete",
    "Met": "Use only within the relevant conditions after existing content review; no automatic designation in this preparation",
    "Not reported": "Distinguish only within materials actually read; do not turn unread external materials into unreported findings",
    "Inaccessible": "Not applied during this preparation because actual access was not tested",
    "Not applicable": "Use with a reason for non-applicability based on an explicit question boundary",
    "Conflicting data": "Judge after actual material comparison; review was not performed during this preparation",
    "Insufficient evidence for the conditions": "Do not use as a clinical grade encompassing currently unread materials"
  },
  "requirements": [
    {
      "item_id": "N01",
      "question_type": "Comparative efficacy",
      "question": "Are the selected sixteen-week comparison and subclaim grade distinguished from the parent context?",
      "needed": "Separate records of the selected wording, grade, note, and parent verdict",
      "role": "Required",
      "role_reason": "An individual production condition recording original values, direct comparisons and application boundaries for the selected question",
      "application_exception": "Unread external materials, different comparisons or out-of-scope results do not substitute for fulfilled conditions, zero effect or safety.",
      "criterion": "Separate records of the selected wording, grade, note, and parent verdict",
      "basis": "Sixteen-week weight loss versus no diet change",
      "condition_origin": "Question-specific application conditions; existing content review remains incomplete and common definitions are not automatically fulfilled",
      "proposed_research": "If additional materials are provided, connect the selected question and the parent's application boundaries separately."
    },
    {
      "item_id": "N02",
      "question_type": "Comparative efficacy",
      "question": "Who were the overweight adults in the trial, and what were their baseline characteristics?",
      "needed": "Eligibility, age, BMI, comorbidities, baseline weight, and group denominators",
      "role": "Required",
      "role_reason": "An individual production condition recording original values, direct comparisons and application boundaries for the selected question",
      "application_exception": "Unread external materials, different comparisons or out-of-scope results do not substitute for fulfilled conditions, zero effect or safety.",
      "criterion": "Eligibility, age, BMI, comorbidities, baseline weight, and group denominators",
      "basis": "Sixteen-week weight loss versus no diet change",
      "condition_origin": "Question-specific application conditions; existing content review remains incomplete and common definitions are not automatically fulfilled",
      "proposed_research": "Obtain the original trial's eligibility criteria, baseline characteristics table, and denominators."
    },
    {
      "item_id": "N03",
      "question_type": "Comparative efficacy",
      "question": "What was the ad libitum low-fat vegan composite diet?",
      "needed": "Study records of diet composition, education, support, actual intake, and exposure",
      "role": "Required",
      "role_reason": "An individual production condition recording original values, direct comparisons and application boundaries for the selected question",
      "application_exception": "Unread external materials, different comparisons or out-of-scope results do not substitute for fulfilled conditions, zero effect or safety.",
      "criterion": "Study records of diet composition, education, support, actual intake, and exposure",
      "basis": "Sixteen-week weight loss versus no diet change",
      "condition_origin": "Question-specific application conditions; existing content review remains incomplete and common definitions are not automatically fulfilled",
      "proposed_research": "Connect original materials on diet composition, education, actual intake, and adherence."
    },
    {
      "item_id": "N04",
      "question_type": "Comparative efficacy",
      "question": "Are food and supplement provision distinguished from classes and support?",
      "needed": "Original group records of food provision, supplements, contact, classes, and support",
      "role": "Required",
      "role_reason": "An individual production condition recording original values, direct comparisons and application boundaries for the selected question",
      "application_exception": "Unread external materials, different comparisons or out-of-scope results do not substitute for fulfilled conditions, zero effect or safety.",
      "criterion": "Original group records of food provision, supplements, contact, classes, and support",
      "basis": "Sixteen-week weight loss versus no diet change",
      "condition_origin": "Question-specific application conditions; existing content review remains incomplete and common definitions are not automatically fulfilled",
      "proposed_research": "Obtain group records of classes, support, contact, participation, and exposure to food or supplements."
    },
    {
      "item_id": "N05",
      "question_type": "Comparative efficacy",
      "question": "Are a no-change control and other healthy-diet controls different comparisons?",
      "needed": "Original records of actual control diet, management, and additional treatment",
      "role": "Required",
      "role_reason": "An individual production condition recording original values, direct comparisons and application boundaries for the selected question",
      "application_exception": "Unread external materials, different comparisons or out-of-scope results do not substitute for fulfilled conditions, zero effect or safety.",
      "criterion": "Original records of actual control diet, management, and additional treatment",
      "basis": "Sixteen-week weight loss versus no diet change",
      "condition_origin": "Question-specific application conditions; existing content review remains incomplete and common definitions are not automatically fulfilled",
      "proposed_research": "Connect the original control's actual exposure and direct comparisons with other healthy diets separately."
    },
    {
      "item_id": "N06",
      "question_type": "Comparative efficacy",
      "question": "Does ad libitum establish matched actual calories or intake?",
      "needed": "Distinction between prescribed calories, actual intake, energy differences, and study exposure",
      "role": "Required",
      "role_reason": "An individual production condition recording original values, direct comparisons and application boundaries for the selected question",
      "application_exception": "Unread external materials, different comparisons or out-of-scope results do not substitute for fulfilled conditions, zero effect or safety.",
      "criterion": "Distinction between prescribed calories, actual intake, energy differences, and study exposure",
      "basis": "Sixteen-week weight loss versus no diet change",
      "condition_origin": "Question-specific application conditions; existing content review remains incomplete and common definitions are not automatically fulfilled",
      "proposed_research": "Connect actual intake, exposure, energy measurements, and prespecified analysis materials when provided."
    },
    {
      "item_id": "N07",
      "question_type": "Comparative efficacy",
      "question": "What were the units, methods, and timing of sixteen-week weight measurement?",
      "needed": "Baseline and sixteen-week measurements, calibrated scale, units, and procedures",
      "role": "Required",
      "role_reason": "An individual production condition recording original values, direct comparisons and application boundaries for the selected question",
      "application_exception": "Unread external materials, different comparisons or out-of-scope results do not substitute for fulfilled conditions, zero effect or safety.",
      "criterion": "Baseline and sixteen-week measurements, calibrated scale, units, and procedures",
      "basis": "Sixteen-week weight loss versus no diet change",
      "condition_origin": "Question-specific application conditions; existing content review remains incomplete and common definitions are not automatically fulfilled",
      "proposed_research": "Obtain original measurement procedures, group labels, and values at each time point."
    },
    {
      "item_id": "N08",
      "question_type": "Comparative efficacy",
      "question": "Are within-group weight changes and the between-group treatment effect preserved as recorded?",
      "needed": "Original materials for group changes, treatment effect, CI, and testing",
      "role": "Required",
      "role_reason": "An individual production condition recording original values, direct comparisons and application boundaries for the selected question",
      "application_exception": "Unread external materials, different comparisons or out-of-scope results do not substitute for fulfilled conditions, zero effect or safety.",
      "criterion": "Original materials for group changes, treatment effect, CI, and testing",
      "basis": "Sixteen-week weight loss versus no diet change",
      "condition_origin": "Question-specific application conditions; existing content review remains incomplete and common definitions are not automatically fulfilled",
      "proposed_research": "Connect the original between-group model, effect, interval, denominators, and group tables."
    },
    {
      "item_id": "N09",
      "question_type": "Comparative efficacy",
      "question": "Are randomization, completion, and analysis populations distinguished?",
      "needed": "Allocation, completion, ITT, missing data, and group analysis denominators",
      "role": "Required",
      "role_reason": "An individual production condition recording original values, direct comparisons and application boundaries for the selected question",
      "application_exception": "Unread external materials, different comparisons or out-of-scope results do not substitute for fulfilled conditions, zero effect or safety.",
      "criterion": "Allocation, completion, ITT, missing data, and group analysis denominators",
      "basis": "Sixteen-week weight loss versus no diet change",
      "condition_origin": "Question-specific application conditions; existing content review remains incomplete and common definitions are not automatically fulfilled",
      "proposed_research": "Obtain group follow-up flow, analysis populations, reasons for missing data, and endpoint-specific denominators."
    },
    {
      "item_id": "N10",
      "question_type": "Comparative efficacy",
      "question": "Are the limitations of ITT and a repeated-measures model incorporating missing data recorded?",
      "needed": "Prespecified original plans for model, missing-data assumptions, variables, sensitivity, and exclusions",
      "role": "Required",
      "role_reason": "An individual production condition recording original values, direct comparisons and application boundaries for the selected question",
      "application_exception": "Unread external materials, different comparisons or out-of-scope results do not substitute for fulfilled conditions, zero effect or safety.",
      "criterion": "Prespecified original plans for model, missing-data assumptions, variables, sensitivity, and exclusions",
      "basis": "Sixteen-week weight loss versus no diet change",
      "condition_origin": "Question-specific application conditions; existing content review remains incomplete and common definitions are not automatically fulfilled",
      "proposed_research": "Obtain the original SAP and materials on missing-data handling, group attrition, and sensitivity analyses."
    },
    {
      "item_id": "N11",
      "question_type": "Comparative efficacy",
      "question": "What information is available about allocation, participant masking, and measurement procedures?",
      "needed": "Original methods for allocation, concealment, and assessor and analyst masking",
      "role": "Required",
      "role_reason": "An individual production condition recording original values, direct comparisons and application boundaries for the selected question",
      "application_exception": "Unread external materials, different comparisons or out-of-scope results do not substitute for fulfilled conditions, zero effect or safety.",
      "criterion": "Original methods for allocation, concealment, and assessor and analyst masking",
      "basis": "Sixteen-week weight loss versus no diet change",
      "condition_origin": "Question-specific application conditions; existing content review remains incomplete and common definitions are not automatically fulfilled",
      "proposed_research": "Obtain original allocation, concealment, assessor, and analyst procedures and methods."
    },
    {
      "item_id": "N12",
      "question_type": "Comparative efficacy",
      "question": "Are multiple primary outcomes distinguished from the prespecified hierarchy of the weight question?",
      "needed": "Original records of registration, protocol, SAP, multiplicity, and effect of interest",
      "role": "Required",
      "role_reason": "An individual production condition recording original values, direct comparisons and application boundaries for the selected question",
      "application_exception": "Unread external materials, different comparisons or out-of-scope results do not substitute for fulfilled conditions, zero effect or safety.",
      "criterion": "Original records of registration, protocol, SAP, multiplicity, and effect of interest",
      "basis": "Sixteen-week weight loss versus no diet change",
      "condition_origin": "Question-specific application conditions; existing content review remains incomplete and common definitions are not automatically fulfilled",
      "proposed_research": "Connect outcome hierarchy, testing, and change histories in the registration, protocol, and SAP."
    },
    {
      "item_id": "N13",
      "question_type": "Comparative efficacy",
      "question": "Is a large kilogram difference distinguished from a verified clinical-importance threshold?",
      "needed": "Prespecified minimum clinically important weight-loss threshold and original plan for the selected population and duration",
      "role": "Required",
      "role_reason": "An individual production condition recording original values, direct comparisons and application boundaries for the selected question",
      "application_exception": "Unread external materials, different comparisons or out-of-scope results do not substitute for fulfilled conditions, zero effect or safety.",
      "criterion": "Prespecified minimum clinically important weight-loss threshold and original plan for the selected population and duration",
      "basis": "Sixteen-week weight loss versus no diet change",
      "condition_origin": "Question-specific application conditions; existing content review remains incomplete and common definitions are not automatically fulfilled",
      "proposed_research": "Connect prespecified importance, meaningful response, and population-specific application plans when provided."
    },
    {
      "item_id": "N14",
      "question_type": "Comparative efficacy",
      "question": "Are weight, other surrogate outcomes, body composition, and mechanisms supported separately?",
      "needed": "Endpoint-specific materials for weight, insulin, postprandial metabolism, body composition, and intracellular lipids",
      "role": "Required",
      "role_reason": "An individual production condition recording original values, direct comparisons and application boundaries for the selected question",
      "application_exception": "Unread external materials, different comparisons or out-of-scope results do not substitute for fulfilled conditions, zero effect or safety.",
      "criterion": "Endpoint-specific materials for weight, insulin, postprandial metabolism, body composition, and intracellular lipids",
      "basis": "Sixteen-week weight loss versus no diet change",
      "condition_origin": "Question-specific application conditions; existing content review remains incomplete and common definitions are not automatically fulfilled",
      "proposed_research": "Obtain each endpoint's definition, measurement, denominators, effect, CI, and prespecified plan separately."
    },
    {
      "item_id": "N15",
      "question_type": "Comparative efficacy",
      "question": "Was the sixteen-week result extended to long-term maintenance, disease, or death?",
      "needed": "Direct follow-up, denominators, and effects for long-term weight and clinical events",
      "role": "Required",
      "role_reason": "An individual production condition recording original values, direct comparisons and application boundaries for the selected question",
      "application_exception": "Unread external materials, different comparisons or out-of-scope results do not substitute for fulfilled conditions, zero effect or safety.",
      "criterion": "Direct follow-up, denominators, and effects for long-term weight and clinical events",
      "basis": "Sixteen-week weight loss versus no diet change",
      "condition_origin": "Question-specific application conditions; existing content review remains incomplete and common definitions are not automatically fulfilled",
      "proposed_research": "Connect separate long-term direct comparisons and clinical-event materials for the relevant population."
    },
    {
      "item_id": "N16",
      "question_type": "Comparative efficacy",
      "question": "Is the seventy-four-week diabetes-diet comparison the same as a sixteen-week no-change comparison?",
      "needed": "Direct comparisons and original denominators separated by population, comparator, and duration",
      "role": "Required",
      "role_reason": "An individual production condition recording original values, direct comparisons and application boundaries for the selected question",
      "application_exception": "Unread external materials, different comparisons or out-of-scope results do not substitute for fulfilled conditions, zero effect or safety.",
      "criterion": "Direct comparisons and original denominators separated by population, comparator, and duration",
      "basis": "Sixteen-week weight loss versus no diet change",
      "condition_origin": "Question-specific application conditions; existing content review remains incomplete and common definitions are not automatically fulfilled",
      "proposed_research": "Connect each trial's population, diet composition, denominators, effect, and CI separately."
    },
    {
      "item_id": "N17",
      "question_type": "Comparative efficacy",
      "question": "Does the NEW Soul active-control result concern a different population and duration?",
      "needed": "Original NEW Soul materials on population, the two diets, endpoints, and denominators",
      "role": "Required",
      "role_reason": "An individual production condition recording original values, direct comparisons and application boundaries for the selected question",
      "application_exception": "Unread external materials, different comparisons or out-of-scope results do not substitute for fulfilled conditions, zero effect or safety.",
      "criterion": "Original NEW Soul materials on population, the two diets, endpoints, and denominators",
      "basis": "Sixteen-week weight loss versus no diet change",
      "condition_origin": "Question-specific application conditions; existing content review remains incomplete and common definitions are not automatically fulfilled",
      "proposed_research": "Obtain NEW Soul's original population, comparator composition, denominators, hierarchy, and CI."
    },
    {
      "item_id": "N18",
      "question_type": "Comparative efficacy",
      "question": "Are null active-comparison results kept separate from the original sixteen-week E+ and R1?",
      "needed": "Relationships between results with matching populations, comparisons, and time points",
      "role": "Required",
      "role_reason": "An individual production condition recording original values, direct comparisons and application boundaries for the selected question",
      "application_exception": "Unread external materials, different comparisons or out-of-scope results do not substitute for fulfilled conditions, zero effect or safety.",
      "criterion": "Relationships between results with matching populations, comparisons, and time points",
      "basis": "Sixteen-week weight loss versus no diet change",
      "condition_origin": "Question-specific application conditions; existing content review remains incomplete and common definitions are not automatically fulfilled",
      "proposed_research": "Connect each comparison question's plan, CI, importance, and application scope separately."
    },
    {
      "item_id": "N19",
      "question_type": "Comparative efficacy",
      "question": "Were shared reports, sibling questions, and the same participants kept from being counted as independent replication?",
      "needed": "Study-family connections among original bibliography, trials, participants, and endpoints",
      "role": "Required",
      "role_reason": "An individual production condition recording original values, direct comparisons and application boundaries for the selected question",
      "application_exception": "Unread external materials, different comparisons or out-of-scope results do not substitute for fulfilled conditions, zero effect or safety.",
      "criterion": "Study-family connections among original bibliography, trials, participants, and endpoints",
      "basis": "Sixteen-week weight loss versus no diet change",
      "condition_origin": "Question-specific application conditions; existing content review remains incomplete and common definitions are not automatically fulfilled",
      "proposed_research": "Connect additional reports through original trial identifiers while retaining same-population relationships."
    },
    {
      "item_id": "N20",
      "question_type": "Comparative efficacy",
      "question": "Are PCRM, public grants, and organizational author roles distinguished?",
      "needed": "Separate records of support, organizational roles, affiliations, design, analysis, and writing",
      "role": "Required",
      "role_reason": "An individual production condition recording original values, direct comparisons and application boundaries for the selected question",
      "application_exception": "Unread external materials, different comparisons or out-of-scope results do not substitute for fulfilled conditions, zero effect or safety.",
      "criterion": "Separate records of support, organizational roles, affiliations, design, analysis, and writing",
      "basis": "Sixteen-week weight loss versus no diet change",
      "condition_origin": "Question-specific application conditions; existing content review remains incomplete and common definitions are not automatically fulfilled",
      "proposed_research": "Obtain original funding, affiliations, study roles, data-access, and analysis disclosures separately."
    },
    {
      "item_id": "N21",
      "question_type": "Comparative efficacy",
      "question": "Are no food provision and gaps in other interests or external analysis roles distinguished?",
      "needed": "Separate materials on product provision, monetary support, affiliated authors, and external analysis services",
      "role": "Required",
      "role_reason": "An individual production condition recording original values, direct comparisons and application boundaries for the selected question",
      "application_exception": "Unread external materials, different comparisons or out-of-scope results do not substitute for fulfilled conditions, zero effect or safety.",
      "criterion": "Separate materials on product provision, monetary support, affiliated authors, and external analysis services",
      "basis": "Sixteen-week weight loss versus no diet change",
      "condition_origin": "Question-specific application conditions; existing content review remains incomplete and common definitions are not automatically fulfilled",
      "proposed_research": "Connect original disclosures of sponsorship, products, affiliations, and external analysis and writing roles."
    },
    {
      "item_id": "N22",
      "question_type": "Comparative efficacy",
      "question": "Is the level of funding information preserved separately for the other two active-comparison trials?",
      "needed": "Original support, provision, affiliations, and analysis roles for each trial",
      "role": "Required",
      "role_reason": "An individual production condition recording original values, direct comparisons and application boundaries for the selected question",
      "application_exception": "Unread external materials, different comparisons or out-of-scope results do not substitute for fulfilled conditions, zero effect or safety.",
      "criterion": "Original support, provision, affiliations, and analysis roles for each trial",
      "basis": "Sixteen-week weight loss versus no diet change",
      "condition_origin": "Question-specific application conditions; existing content review remains incomplete and common definitions are not automatically fulfilled",
      "proposed_research": "Obtain each trial's original support, affiliation, provision, and analysis disclosures separately."
    },
    {
      "item_id": "N23",
      "question_type": "Supplementary harm evidence",
      "question": "Are prespecified safety outcomes, adverse-event comparisons, and unread materials distinguished?",
      "needed": "Harm collection, group events, exposure, denominators, and prespecified plans",
      "role": "Required",
      "role_reason": "An individual production condition recording original values, direct comparisons and application boundaries for the selected question",
      "application_exception": "Unread external materials, different comparisons or out-of-scope results do not substitute for fulfilled conditions, zero effect or safety.",
      "criterion": "Harm collection, group events, exposure, denominators, and prespecified plans",
      "basis": "Sixteen-week weight loss versus no diet change",
      "condition_origin": "Question-specific application conditions; existing content review remains incomplete and common definitions are not automatically fulfilled",
      "proposed_research": "Obtain original harm-collection methods, group events, exposure, discontinuations, and denominators."
    },
    {
      "item_id": "N24",
      "question_type": "Supplementary harm evidence",
      "question": "Are gaps in short-term and long-term nutritional harms and rare events preserved?",
      "needed": "Actual dietary exposure, discontinuation, group harms, and long-term follow-up",
      "role": "Required",
      "role_reason": "An individual production condition recording original values, direct comparisons and application boundaries for the selected question",
      "application_exception": "Unread external materials, different comparisons or out-of-scope results do not substitute for fulfilled conditions, zero effect or safety.",
      "criterion": "Actual dietary exposure, discontinuation, group harms, and long-term follow-up",
      "basis": "Sixteen-week weight loss versus no diet change",
      "condition_origin": "Question-specific application conditions; existing content review remains incomplete and common definitions are not automatically fulfilled",
      "proposed_research": "Direct materials on actual exposure, discontinuation, nutrition-related measurements, rare harms, and long-term follow-up are needed."
    },
    {
      "item_id": "N25",
      "question_type": "Supplementary harm evidence",
      "question": "Was new certainty avoided for application to special populations, concomitant treatment, and replication of harms?",
      "needed": "Population-specific direct comparisons, exposure, harms, and follow-up materials",
      "role": "Required",
      "role_reason": "An individual production condition recording original values, direct comparisons and application boundaries for the selected question",
      "application_exception": "Unread external materials, different comparisons or out-of-scope results do not substitute for fulfilled conditions, zero effect or safety.",
      "criterion": "Population-specific direct comparisons, exposure, harms, and follow-up materials",
      "basis": "Sixteen-week weight loss versus no diet change",
      "condition_origin": "Question-specific application conditions; existing content review remains incomplete and common definitions are not automatically fulfilled",
      "proposed_research": "If direct materials and trial–harm relationships for those populations are provided, connect them separately."
    },
    {
      "item_id": "N26",
      "question_type": "Comparative efficacy",
      "question": "Are external links and registration identifiers separated from actual access status?",
      "needed": "Separate access records for summaries, abstracts, full texts, registrations, protocols, and SAPs",
      "role": "Required",
      "role_reason": "An individual production condition recording original values, direct comparisons and application boundaries for the selected question",
      "application_exception": "Unread external materials, different comparisons or out-of-scope results do not substitute for fulfilled conditions, zero effect or safety.",
      "criterion": "Separate access records for summaries, abstracts, full texts, registrations, protocols, and SAPs",
      "basis": "Sixteen-week weight loss versus no diet change",
      "condition_origin": "Question-specific application conditions; existing content review remains incomplete and common definitions are not automatically fulfilled",
      "proposed_research": "Connect only materials obtained by the user, with separate access status for each."
    },
    {
      "item_id": "N27",
      "question_type": "Comparative efficacy",
      "question": "Are the reference date, Korean and English text, original axes, corrections, and empty values preserved?",
      "needed": "Separate records of the full original text and subclaim and parent histories",
      "role": "Required",
      "role_reason": "An individual production condition recording original values, direct comparisons and application boundaries for the selected question",
      "application_exception": "Unread external materials, different comparisons or out-of-scope results do not substitute for fulfilled conditions, zero effect or safety.",
      "criterion": "Separate records of the full original text and subclaim and parent histories",
      "basis": "Sixteen-week weight loss versus no diet change",
      "condition_origin": "Question-specific application conditions; existing content review remains incomplete and common definitions are not automatically fulfilled",
      "proposed_research": "Proposal: Link new materials or decisions to separate change events while preserving original text."
    },
    {
      "item_id": "N28",
      "question_type": "Comparative efficacy",
      "question": "Are production status, original content review, and independent certification distinguished?",
      "needed": "Separate records of existing candidate history, production, and review status",
      "role": "Supplementary",
      "role_reason": "An individual production condition recording original values, direct comparisons and application boundaries for the selected question",
      "application_exception": "Unread external materials, different comparisons or out-of-scope results do not substitute for fulfilled conditions, zero effect or safety.",
      "criterion": "Separate records of existing candidate history, production, and review status",
      "basis": "Sixteen-week weight loss versus no diet change",
      "condition_origin": "Question-specific application conditions; existing content review remains incomplete and common definitions are not automatically fulfilled",
      "proposed_research": "Reflect only user-provided decisions and materials as separate events."
    }
  ]
}