{
  "schema_version": "chamgap-public-criteria-1.0",
  "title": "Routine thrombus aspiration added × Thirty-day all-cause mortality in STEMI — TASTE evidence sheet",
  "language": "en",
  "translation_date": "2026-10-10",
  "criteria_version": "1.0",
  "criteria_date": "2026-10-06",
  "condition_origin": "Chamgap's own application conditions",
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      "url": "https://www.cochrane.org/authors/handbooks-and-manuals/handbook/current/chapter-03",
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      "official_principle": "Clearly record the question, eligibility conditions and reasons for changes, and distinguish variations in interventions.",
      "review_level": "Existing stored methodological links reused for preparation; no current review, reassessment of methodological content or external-link testing"
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      "official_principle": "Distinguish studies from reports and link them; do not omit a study solely because results are unreported.",
      "review_level": "Existing stored methodological links reused for preparation; no current review, reassessment of methodological content or external-link testing"
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      "id": "M08",
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      "url": "https://www.cochrane.org/authors/handbooks-and-manuals/handbook/current/chapter-08",
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      "official_principle": "Define the outcome and effect of interest, then examine randomization, deviations, missing data, measurement and selective reporting.",
      "review_level": "Existing stored methodological links reused for preparation; no current review, reassessment of methodological content or external-link testing"
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      "version": "Cochrane Handbook 6.5 (2024), chapter updated 2023-08",
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      "section": "§15.2.4, §15.3.1–15.3.3",
      "official_principle": "Distinguish effect estimates, intervals, importance and applicability. Sample size alone does not determine precision.",
      "review_level": "Existing stored methodological links reused for preparation; no current review, reassessment of methodological content or external-link testing"
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      "id": "M19",
      "version": "Cochrane Handbook 6.5 (2024), chapter updated 2019-10",
      "url": "https://www.cochrane.org/authors/handbooks-and-manuals/handbook/current/chapter-19",
      "section": "§19.1.2, §19.2.1–19.2.4",
      "official_principle": "Harm questions may require different designs, populations and follow-up from efficacy questions. Case reports do not establish incidence rates.",
      "review_level": "Existing stored methodological links reused for preparation; no current review, reassessment of methodological content or external-link testing"
    }
  ],
  "status_dictionary": {
    "Partly verified": "Some information is present in the stored source, with detailed original materials still unverified; this does not mean review passed or clinical efficacy certified",
    "Unverified": "Detailed materials for the selected condition could not be established within the stored scope; this does not mean zero effect, zero studies or safety",
    "Review incomplete": "Awaiting user review",
    "Met": "Use only within the relevant condition's scope after user review; no automatic display in this preparation",
    "Not reported": "Distinguish only within materials actually read; do not turn unread external materials into unreported findings",
    "Inaccessible": "Not applied during this preparation because actual access was not tested",
    "Not applicable": "Use with a reason for non-applicability based on an explicit question boundary",
    "Conflicting data": "Judge after actual material comparison; review was not performed during this preparation",
    "Insufficient evidence for the conditions": "Do not use as a clinical grade encompassing currently unread materials"
  },
  "requirements": [
    {
      "item_id": "N01",
      "question_type": "Comparative efficacy",
      "question": "Were the selected claim and existing verdict record distinguished?",
      "needed": "Preservation of the existing claim wording, verdict values, history and empty values",
      "role": "Required",
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      "application_exception": "Do not use unread materials, other questions, institutions or periods, or out-of-scope outcomes as substitutes for meeting a condition, a zero effect or safety.",
      "criterion": "Preservation of the existing claim wording, verdict values, history and empty values",
      "basis": "Selected claim: Reduced thirty-day all-cause mortality in ST-elevation myocardial infarction",
      "condition_origin": "Individual preparation condition; completed review or automatic fulfillment of a common definition is not implied",
      "proposed_research": "Link original materials and decisions to the actual MAIN question and root verdict record."
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      "item_id": "N02",
      "question_type": "Comparative efficacy",
      "question": "What are the actual population, eligibility and baseline for primary PCI in STEMI?",
      "needed": "Original STEMI, entry time, PCI, eligibility, institutions and denominators",
      "role": "Required",
      "role_reason": "An individual preparation condition recording the population, endpoint, denominator, period, efficacy, harm and report relationships of the existing native MAIN claim",
      "application_exception": "Do not use unread materials, other questions, institutions or periods, or out-of-scope outcomes as substitutes for meeting a condition, a zero effect or safety.",
      "criterion": "Original STEMI, entry time, PCI, eligibility, institutions and denominators",
      "basis": "Selected claim: Reduced thirty-day all-cause mortality in ST-elevation myocardial infarction",
      "condition_origin": "Individual preparation condition; completed review or automatic fulfillment of a common definition is not implied",
      "proposed_research": "Obtain original population, diagnosis, eligibility, time points, institutions, baseline and denominator materials."
    },
    {
      "item_id": "N03",
      "question_type": "Comparative efficacy",
      "question": "Do routine aspiration added, PCI itself and selective aspiration involve the same comparison?",
      "needed": "Original additional procedure, comparator, common PCI, actual exposure and concurrent treatment",
      "role": "Required",
      "role_reason": "An individual preparation condition recording the population, endpoint, denominator, period, efficacy, harm and report relationships of the existing native MAIN claim",
      "application_exception": "Do not use unread materials, other questions, institutions or periods, or out-of-scope outcomes as substitutes for meeting a condition, a zero effect or safety.",
      "criterion": "Original additional procedure, comparator, common PCI, actual exposure and concurrent treatment",
      "basis": "Selected claim: Reduced thirty-day all-cause mortality in ST-elevation myocardial infarction",
      "condition_origin": "Individual preparation condition; completed review or automatic fulfillment of a common definition is not implied",
      "proposed_research": "Obtain original aspiration, comparator, actual implementation, rescue, crossover and common-treatment materials."
    },
    {
      "item_id": "N04",
      "question_type": "Comparative efficacy",
      "question": "Are SWEDEHEART registry randomization and observational associations distinguished?",
      "needed": "Original recruitment, randomization, registry follow-up, analysis and institutions",
      "role": "Required",
      "role_reason": "An individual preparation condition recording the population, endpoint, denominator, period, efficacy, harm and report relationships of the existing native MAIN claim",
      "application_exception": "Do not use unread materials, other questions, institutions or periods, or out-of-scope outcomes as substitutes for meeting a condition, a zero effect or safety.",
      "criterion": "Original recruitment, randomization, registry follow-up, analysis and institutions",
      "basis": "Selected claim: Reduced thirty-day all-cause mortality in ST-elevation myocardial infarction",
      "condition_origin": "Individual preparation condition; completed review or automatic fulfillment of a common definition is not implied",
      "proposed_research": "Obtain original registry recruitment, allocation, follow-up, ascertainment and denominators."
    },
    {
      "item_id": "N05",
      "question_type": "Comparative efficacy",
      "question": "Were the 7,244 participants and each group's mortality denominators preserved in their original form?",
      "needed": "Original allocation, groups, deaths, analysis and follow-up denominators",
      "role": "Required",
      "role_reason": "An individual preparation condition recording the population, endpoint, denominator, period, efficacy, harm and report relationships of the existing native MAIN claim",
      "application_exception": "Do not use unread materials, other questions, institutions or periods, or out-of-scope outcomes as substitutes for meeting a condition, a zero effect or safety.",
      "criterion": "Original allocation, groups, deaths, analysis and follow-up denominators",
      "basis": "Selected claim: Reduced thirty-day all-cause mortality in ST-elevation myocardial infarction",
      "condition_origin": "Individual preparation condition; completed review or automatic fulfillment of a common definition is not implied",
      "proposed_research": "Obtain original allocation, analysis, group denominators, events and follow-up tables."
    },
    {
      "item_id": "N06",
      "question_type": "Comparative efficacy",
      "question": "What are the thirty-day all-cause mortality definition and national-registry ascertainment?",
      "needed": "Death definition, reference point, thirty-day window, registry and external events",
      "role": "Required",
      "role_reason": "An individual preparation condition recording the population, endpoint, denominator, period, efficacy, harm and report relationships of the existing native MAIN claim",
      "application_exception": "Do not use unread materials, other questions, institutions or periods, or out-of-scope outcomes as substitutes for meeting a condition, a zero effect or safety.",
      "criterion": "Death definition, reference point, thirty-day window, registry and external events",
      "basis": "Selected claim: Reduced thirty-day all-cause mortality in ST-elevation myocardial infarction",
      "condition_origin": "Individual preparation condition; completed review or automatic fulfillment of a common definition is not implied",
      "proposed_research": "Obtain original death definitions, time points, ascertainment, registry linkage and denominators."
    },
    {
      "item_id": "N07",
      "question_type": "Comparative efficacy",
      "question": "Are HR 0.94, the 95% CI of 0.72–1.22 and the original −0.2 percentage points preserved?",
      "needed": "Original time-to-event effect, comparison direction, interval, absolute difference and model",
      "role": "Required",
      "role_reason": "An individual preparation condition recording the population, endpoint, denominator, period, efficacy, harm and report relationships of the existing native MAIN claim",
      "application_exception": "Do not use unread materials, other questions, institutions or periods, or out-of-scope outcomes as substitutes for meeting a condition, a zero effect or safety.",
      "criterion": "Original time-to-event effect, comparison direction, interval, absolute difference and model",
      "basis": "Selected claim: Reduced thirty-day all-cause mortality in ST-elevation myocardial infarction",
      "condition_origin": "Individual preparation condition; completed review or automatic fulfillment of a common definition is not implied",
      "proposed_research": "Obtain original effect direction, models, tests, CI and denominators."
    },
    {
      "item_id": "N08",
      "question_type": "Comparative efficacy",
      "question": "Were the null result and CI tails allowing benefit and harm distinguished?",
      "needed": "Original interval, clinical boundaries, precision and interpretation",
      "role": "Required",
      "role_reason": "An individual preparation condition recording the population, endpoint, denominator, period, efficacy, harm and report relationships of the existing native MAIN claim",
      "application_exception": "Do not use unread materials, other questions, institutions or periods, or out-of-scope outcomes as substitutes for meeting a condition, a zero effect or safety.",
      "criterion": "Original interval, clinical boundaries, precision and interpretation",
      "basis": "Selected claim: Reduced thirty-day all-cause mortality in ST-elevation myocardial infarction",
      "condition_origin": "Individual preparation condition; completed review or automatic fulfillment of a common definition is not implied",
      "proposed_research": "Obtain original clinical boundaries, precision, denominators and assumptions."
    },
    {
      "item_id": "N09",
      "question_type": "Comparative efficacy",
      "question": "Were the roles of online allocation, unmasked procedures, objective mortality and ITT distinguished?",
      "needed": "Allocation, concealment, blinding, event ascertainment, analysis and missingness",
      "role": "Required",
      "role_reason": "An individual preparation condition recording the population, endpoint, denominator, period, efficacy, harm and report relationships of the existing native MAIN claim",
      "application_exception": "Do not use unread materials, other questions, institutions or periods, or out-of-scope outcomes as substitutes for meeting a condition, a zero effect or safety.",
      "criterion": "Allocation, concealment, blinding, event ascertainment, analysis and missingness",
      "basis": "Selected claim: Reduced thirty-day all-cause mortality in ST-elevation myocardial infarction",
      "condition_origin": "Individual preparation condition; completed review or automatic fulfillment of a common definition is not implied",
      "proposed_research": "Obtain original allocation, ascertainment, actual procedures, analysis and missing-data materials."
    },
    {
      "item_id": "N10",
      "question_type": "Comparative efficacy",
      "question": "What are the access gaps for registration, prespecified thirty-day mortality, hierarchy and subgroups?",
      "needed": "Registration, protocol, SAP, hierarchy, changes and models",
      "role": "Required",
      "role_reason": "An individual preparation condition recording the population, endpoint, denominator, period, efficacy, harm and report relationships of the existing native MAIN claim",
      "application_exception": "Do not use unread materials, other questions, institutions or periods, or out-of-scope outcomes as substitutes for meeting a condition, a zero effect or safety.",
      "criterion": "Registration, protocol, SAP, hierarchy, changes and models",
      "basis": "Selected claim: Reduced thirty-day all-cause mortality in ST-elevation myocardial infarction",
      "condition_origin": "Individual preparation condition; completed review or automatic fulfillment of a common definition is not implied",
      "proposed_research": "Obtain original registration, plans, hierarchy, subgroups, changes and models."
    },
    {
      "item_id": "N11",
      "question_type": "Comparative efficacy",
      "question": "Was the finding extended to longer periods, specific patients, rescue aspiration or procedural mechanisms?",
      "needed": "Periods, populations, selective exposure and direct clinical outcomes",
      "role": "Required",
      "role_reason": "An individual preparation condition recording the population, endpoint, denominator, period, efficacy, harm and report relationships of the existing native MAIN claim",
      "application_exception": "Do not use unread materials, other questions, institutions or periods, or out-of-scope outcomes as substitutes for meeting a condition, a zero effect or safety.",
      "criterion": "Periods, populations, selective exposure and direct clinical outcomes",
      "basis": "Selected claim: Reduced thirty-day all-cause mortality in ST-elevation myocardial infarction",
      "condition_origin": "Individual preparation condition; completed review or automatic fulfillment of a common definition is not implied",
      "proposed_research": "Obtain original direct subgroup and period-specific outcomes, interactions and actual exposure."
    },
    {
      "item_id": "N12",
      "question_type": "Comparative efficacy",
      "question": "What are the 1791 cross-citation, trial question and relationships within the same report?",
      "needed": "Original bibliography, related verdict, additional-procedure question and cohort relationships",
      "role": "Required",
      "role_reason": "An individual preparation condition recording the population, endpoint, denominator, period, efficacy, harm and report relationships of the existing native MAIN claim",
      "application_exception": "Do not use unread materials, other questions, institutions or periods, or out-of-scope outcomes as substitutes for meeting a condition, a zero effect or safety.",
      "criterion": "Original bibliography, related verdict, additional-procedure question and cohort relationships",
      "basis": "Selected claim: Reduced thirty-day all-cause mortality in ST-elevation myocardial infarction",
      "condition_origin": "Individual preparation condition; completed review or automatic fulfillment of a common definition is not implied",
      "proposed_research": "Link new reports by original identifier, cohort and question."
    },
    {
      "item_id": "N13",
      "question_type": "Comparative efficacy",
      "question": "Were public and regional support distinguished from unrestricted grants from three companies?",
      "needed": "Cash, devices, in-kind support, affiliations, external analysis and research roles",
      "role": "Required",
      "role_reason": "An individual preparation condition recording the population, endpoint, denominator, period, efficacy, harm and report relationships of the existing native MAIN claim",
      "application_exception": "Do not use unread materials, other questions, institutions or periods, or out-of-scope outcomes as substitutes for meeting a condition, a zero effect or safety.",
      "criterion": "Cash, devices, in-kind support, affiliations, external analysis and research roles",
      "basis": "Selected claim: Reduced thirty-day all-cause mortality in ST-elevation myocardial infarction",
      "condition_origin": "Individual preparation condition; completed review or automatic fulfillment of a common definition is not implied",
      "proposed_research": "Obtain original funding, devices, in-kind support, affiliation, design, analysis and writing disclosures."
    },
    {
      "item_id": "N14",
      "question_type": "Supplementary harm evidence",
      "question": "What is the window for stroke or neurological complications of 0.5% and P=.87 at discharge?",
      "needed": "Harm definitions, observation window, people and events, original denominators and tests",
      "role": "Required",
      "role_reason": "An individual preparation condition recording the population, endpoint, denominator, period, efficacy, harm and report relationships of the existing native MAIN claim",
      "application_exception": "Do not use unread materials, other questions, institutions or periods, or out-of-scope outcomes as substitutes for meeting a condition, a zero effect or safety.",
      "criterion": "Harm definitions, observation window, people and events, original denominators and tests",
      "basis": "Selected claim: Reduced thirty-day all-cause mortality in ST-elevation myocardial infarction",
      "condition_origin": "Individual preparation condition; completed review or automatic fulfillment of a common definition is not implied",
      "proposed_research": "Obtain original harm definitions, people, events, periods, denominators, CI and tests."
    },
    {
      "item_id": "N15",
      "question_type": "Supplementary harm evidence",
      "question": "What are the original Good safety label, no-increase finding and gaps in rare or long-term harms?",
      "needed": "Other harms, relatedness, actual exposure, collection and long-term follow-up",
      "role": "Required",
      "role_reason": "An individual preparation condition recording the population, endpoint, denominator, period, efficacy, harm and report relationships of the existing native MAIN claim",
      "application_exception": "Do not use unread materials, other questions, institutions or periods, or out-of-scope outcomes as substitutes for meeting a condition, a zero effect or safety.",
      "criterion": "Other harms, relatedness, actual exposure, collection and long-term follow-up",
      "basis": "Selected claim: Reduced thirty-day all-cause mortality in ST-elevation myocardial infarction",
      "condition_origin": "Individual preparation condition; completed review or automatic fulfillment of a common definition is not implied",
      "proposed_research": "Obtain original overall-harm, exposure, relatedness, discontinuation, denominator and rare or long-term materials."
    },
    {
      "item_id": "N16",
      "question_type": "Comparative efficacy",
      "question": "Were the summary, paper and related-verdict URLs, registration identifier and actual access distinguished?",
      "needed": "Original bibliography, URLs, registration, material-specific access and cross-citations",
      "role": "Required",
      "role_reason": "An individual preparation condition recording the population, endpoint, denominator, period, efficacy, harm and report relationships of the existing native MAIN claim",
      "application_exception": "Do not use unread materials, other questions, institutions or periods, or out-of-scope outcomes as substitutes for meeting a condition, a zero effect or safety.",
      "criterion": "Original bibliography, URLs, registration, material-specific access and cross-citations",
      "basis": "Selected claim: Reduced thirty-day all-cause mortality in ST-elevation myocardial infarction",
      "condition_origin": "Individual preparation condition; completed review or automatic fulfillment of a common definition is not implied",
      "proposed_research": "Link user-provided original materials by material type and actual access."
    },
    {
      "item_id": "N17",
      "question_type": "Comparative efficacy",
      "question": "Were MAIN languages, dates, corrections, empty arrays, false/null, empty values and candidate history preserved?",
      "needed": "Original root verdict, Korean and English, cut-off, corrections, history and presence or absence",
      "role": "Supplementary",
      "role_reason": "An individual preparation condition recording the population, endpoint, denominator, period, efficacy, harm and report relationships of the existing native MAIN claim",
      "application_exception": "Do not use unread materials, other questions, institutions or periods, or out-of-scope outcomes as substitutes for meeting a condition, a zero effect or safety.",
      "criterion": "Original root verdict, Korean and English, cut-off, corrections, history and presence or absence",
      "basis": "Selected claim: Reduced thirty-day all-cause mortality in ST-elevation myocardial infarction",
      "condition_origin": "Individual preparation condition; completed review or automatic fulfillment of a common definition is not implied",
      "proposed_research": "Link user materials and decisions to full original preservation and separate events."
    }
  ]
}